LOCUS       DAVKZI010000001       101877 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKZI010000001 DAVKZI010000000
VERSION     DAVKZI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 101877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.001"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..2648)
                     /locus_tag="VXB18_000001"
     CDS             complement(<1..2648)
                     /locus_tag="VXB18_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0381301.1"
                     /translation="MLLTIHDANLQKVAFIDNEKQGTLNYYDDTWTRSLATGSSTFEF
                     TVFKKAVKSDLPLAKAYHHLNEHAFVSFKYKGKSFVFNIIIVEENEQTIKCYCENLNL
                     ELINELANPYKSNKAMTFKEYCEAMDLLNYTHLSIGINEISDYKRTLEWEGQETKLAR
                     LLSLAKRFDAEIEFDTQLNADSTIKKFSVNVYHENDDNHQGVGRVRNDVIVKYGKNIH
                     SITRKVDKTGIFNTIRPTGKMPTVEEELSGDKGSKSETVKNADGSTTKTTISTASDGT
                     KSKTIVHTKVTKLADKTRITTTTTTRSDGSIEQTVTTSKKGGASTSETKVLKKPNPKE
                     KTNTTEDVLTIEGLDEWEVKNEKGIVEFYQRGQALYAPISMQLYPSTFTHSTGELDQW
                     TRKDFHFETDEPNELRRLGYLKLKKYCYPAITYEVDGFVDADIGDTVKVHDDGFAPLL
                     MIQARVTDQKISFTNPVRNKTIFDNFKALENKLSADIQSAFERLFEAAKPYTIKLSTD
                     NGVIFKNQIGQSLVTPTLYKGGKPVVVGVTWRWALDGEVTTGMTYLVRGSNVTDTVTL
                     TVAAYIGNKEVAVDEISLVNVADGKLGTPGTPGRDGRTPYVNTAWANNATGTDGFSLD
                     SSINKLYIGIYTDFEPNDSTDPKKYKWAKVKGDKGEKGDKGEPGQRGLDGLQGARGEQ
                     GLPGRNGADGRTQYTHIAYSNSADGTKDFSVSASDRAYIGMYVDFNSADSNTPSDYNW
                     TLVKGADGANGVAGKAGTDGRTPYLHIAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQ
                     ADSTDYRVYKWTLIKGADGTGISNVTNYYLATTVSTGITRTSAGWTTTPQPITSDKRY
                     LWNYRVELYTNGTSKTTEPTVIGVHG"
     gene            complement(2650..4164)
                     /locus_tag="VXB18_000002"
     CDS             complement(2650..4164)
                     /locus_tag="VXB18_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEV0381302.1"
                     /translation="MTKIMTFNGVDMSKFFRITDIIRPIGNKRSVSTDNAPLLGVNIQ
                     QVKIGEKEHIIKFDIKTTNAIEMEQLKHDLAGILNVLEPVKITYGDEPDKYYMGLPVD
                     EITPENLTRWFQRSELKIIIPDGVAHSTTLKNFDIDTNETSAPDRIVFNLTNTGTEPA
                     YPIIRIKHNSENGYIGVVNNRAAFELGNREEADTEKYRDSETLIDYRGTNILKGFQNG
                     TKGVAVTNDNKERLVGTLSTTSMWGRNHIELSNRGTVEKNRNNAQSLTWAIPVDSSGE
                     VGSLNDYLLWRQVFMAAVANQYGFIKVTVSDTDGNFLYGVETYKRYQTLDCEYSFFTT
                     DGKGGYKFIKWWYFTGTGAQVGKLDPFSAEKGWSELKRNDDRVQVFFDGSHYDFIIPE
                     IKDKKSAKIHITLGALRDWPLVSHMYVDEFMYRKDFVTKSRDIPNRYPIGSNVVINSE
                     DDSVYIDGISKVSEVVDGSHWPAIPPGKSQLELYFSRFVKKKPTVTIEFEERWI"
     gene            complement(4161..7442)
                     /locus_tag="VXB18_000003"
     CDS             complement(4161..7442)
                     /locus_tag="VXB18_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEV0381303.1"
                     /translation="MADGKVTIVVDVDGNKVKVLNDELDKTAQKGDRGSDSLKKFAIG
                     GAAFKLASKAVDLLTDSLDGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEG
                     LPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLQQFSQMLS
                     AGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSSKLVE
                     LNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATSKTIAENFD
                     ALKVIINAAFGVIVNVIKASTPVFQTLFSILGTGASVISSLTPVIISLVSALVAMRAA
                     NEAITATKNLINSWQTFKTTATGAIQIINLMTAAQATCGSVTKAQMVANLANNGALTA
                     SNLLYGVLTGSISLQTAATIAATAATTAFKAALTALTGPIGLVVAGVGLAVGALVGLW
                     QWLTADSEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTESYQKLADE
                     IVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLVYDKNTDSLSHNNDQIKARISAME
                     AESTWETSQKNLLDIEQKRAEIGEQLKKIAEQRKKWNEESNVSDSVRKERLQELNDKE
                     TELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVISYEGMSKAQQKAVDDMR
                     SKYNELLETTTNMFDQIQMKSAISVDEMIANLQKNQEAVNNWATNLNTLAERGVNEGI
                     LAKLQAMGPQGGLYVQELVNASDEKLATLNEVFTQGGESAMNGLTAGMDTGALGITDK
                     IKGIVQSQVSSLQEEIAAADFPEKGKNIPEGVGDGIKAGAKIASEASKNMANDIKESF
                     TSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFDSLQSDFT
                     YIGEMAMSGLNAGLWSGSGSVMATANSIAERVKATIKSALDIHSPSRAMRDEVGRFIP
                     QGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSSKQTIAEK
                     IKVTMDKSSELLKKALDVAETAVRRPNEMYLNDGTLVAKTGDKFAKYQSEQLRRDNRM
                     KGVLS"
     gene            complement(7435..8004)
                     /locus_tag="VXB18_000004"
     CDS             complement(7435..8004)
                     /locus_tag="VXB18_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381304.1"
                     /translation="MSMKLNDALITNFSIADKEYDIDLSFNKVLDVFEILKEDEMTRL
                     EQAQLIVHLLTGQELYDIKEVVDCWIYIKEHFLGIEKETVQYDLLGNPMPKAKGEEEQ
                     EKLIDFEQDAEYIYASFLQAYGINLLKVQNELTWTEFKALLNALPDNTIMQQIIEIRA
                     WKPEYGGDKNKMRKLQAKYSLGKEGEDNG"
     gene            complement(8017..8505)
                     /locus_tag="VXB18_000005"
     CDS             complement(8017..8505)
                     /locus_tag="VXB18_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381305.1"
                     /translation="MTDIQIELKRTGFPVKIGEVELWFDTSQESLMRFYDMEEELKRR
                     LVQYELDVVSANINNKIERDGVTKEVVAGAIELEKKQLEIQYDLIFGDGTFDKLYSIY
                     PDYNALNNALEQTAIMLHDKLEEVAEQHKTVVKERASHYLNKGKVTPIKNNKKQKKNK
                     KK"
     gene            complement(8570..9019)
                     /locus_tag="VXB18_000006"
     CDS             complement(8570..9019)
                     /locus_tag="VXB18_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0381306.1"
                     /translation="MTRQKNALRGHFVAPYNGGTEPSTEDTWLELAKWISDVSDDTDE
                     KTDDQAYYDGDGVEETTVVSVKGAYTFEGTYDPDDKAQALIAGMKYKTGDDRKLWHKV
                     VSSDRKKQWVGAATATEIKAGSGAASDYEAFGCKLSYNSTPKETGIG"
     gene            complement(9016..9423)
                     /locus_tag="VXB18_000007"
     CDS             complement(9016..9423)
                     /locus_tag="VXB18_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0381307.1"
                     /translation="MRENDFQNVLLKHIKTLNLPVEPRFDYFEDDKDDLVINQIPGGK
                     VDREYMDGTQEVSLPFEIAVKAKKNSVANDTIWLVTSELAKIDLVLPSDNNSYEYMGM
                     EVSRPAMKGKDEQGYYYYTIEIVAKIVIERNKQ"
     gene            complement(9423..9767)
                     /locus_tag="VXB18_000008"
     CDS             complement(9423..9767)
                     /locus_tag="VXB18_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0381308.1"
                     /translation="MSIAIKVDLQKAKQKLSNESMTRGKIAVASKILLDNEQYIPLRG
                     GELRASGRIVGQGDAVVYGTVYARAQFYGSNGIVTFRRYTAPGTGKRWDQVATSKHAE
                     EWARAFVKGMGL"
     gene            complement(9767..10159)
                     /locus_tag="VXB18_000009"
     CDS             complement(9767..10159)
                     /locus_tag="VXB18_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0381309.1"
                     /translation="MIDKRLLKGIDKRLLKDVLTIKKVADKNDYGDEVYSEPLTIKNV
                     RFDRSVGGSGNRNSKTGTGNSKTGTGNSKSRQKQGVIYLYPSLSFVTVDNSWMGAKVN
                     DGIGDYTINGFQTNYYDGEIFSQEIEVI"
     gene            complement(10149..10541)
                     /locus_tag="VXB18_000010"
     CDS             complement(10149..10541)
                     /locus_tag="VXB18_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013794407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381310.1"
                     /translation="MTYLTQEEFDELGFDEVTNFEKLAKRAKIAIDLYTNGIYQKDID
                     FEKEIAYRKSAVKLAMAFQIAYLDASGIMSADDKQLANSVSIGRTSISYSTSQSTSAG
                     QRFNLSMDAENALRQAGFSLVVGVAYDR"
     gene            complement(10584..10817)
                     /locus_tag="VXB18_000011"
     CDS             complement(10584..10817)
                     /locus_tag="VXB18_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381311.1"
                     /translation="MALYKATKNLFFEQLNMDVIVDDIIELDEDYAKEVNKKLKNAFP
                     DVKNVLELVDKNGTLEPEDAPSVEDASQATVED"
     gene            complement(10828..11709)
                     /locus_tag="VXB18_000012"
     CDS             complement(10828..11709)
                     /locus_tag="VXB18_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEV0381312.1"
                     /translation="MPSNQNNAVRRYEKQYAGILETVFGVRAAFSNALAPIQILDGVQ
                     ENSKAFSVKTNNTPVVIGEYKTGENDGGFGDNSGAQSRFGGLTEVKYENTDVNYDYTL
                     TIHEGLDRYTVNNDLNAAVADRLKLQSEAQTRTVNKRIGKYLSDNATKTEALADFTDD
                     KVKALFNKLSAFYTNNEVTAPITVYLRSEFYNAIVDMASVTSAKGATISLDENGLPKY
                     KGFTLEETPAQYFETGVIAIFSPNGIIIPFVGISTARVIEAENFDGVKLQAAAKGGTY
                     TLDDNKKAIYKVTGTIV"
     gene            complement(11727..12290)
                     /locus_tag="VXB18_000013"
     CDS             complement(11727..12290)
                     /locus_tag="VXB18_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEV0381313.1"
                     /translation="MAFTTEELLNLGLTEEQAKSVFALRGKELNEDKSALETIKQERD
                     SLKSQLQKAEEQVEHLKSLENISAEQKDAIDKLQAEYDKYKNEAAAELAQTKKVSAIS
                     LALKDTNAFNPDKLMKFIDVDAIQLDDNGKPQIDEVINGLKESDPYLFKAEESKPSPN
                     ILPQGNPAGEGTSDVDPFQAIIDGYGK"
     gene            complement(12429..13580)
                     /locus_tag="VXB18_000014"
     CDS             complement(12429..13580)
                     /locus_tag="VXB18_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEV0381314.1"
                     /translation="MKKKRKQLTFNDQQFPLQMQGVGDIYEKLQIDIFDRMIKRLKER
                     GSIDLMRNPYIWQLEKLNDMHMLNEQNLKLISERTGIAERLLRDVIENEGLKVYKDTK
                     QQLEEDLNKIPEGEISNGVTDSLEAYSRQAVSDLNLINTTLPKSLQVAYKSIVEETVA
                     QVVAGTKTSDVALHDTIMKWQKNAFTGFVDKGGRHWKADSYARAIIKSTTYKVYNEMR
                     TRPAEELGVDTFYYSMKAMARPACSPLQGQIVTKGAGRKIDGITIYSLLDYGYGTAAG
                     CLGIHCGHYLTPFIVGVHELPNLPDYLKNLTPEQAEENARIEAGQRGLERLIKTHKER
                     LHYAHTLQDDKMIQAERLKVRGYQTKIRNLINQHDFLTRDYRREKLYIS"
     gene            complement(13623..13796)
                     /locus_tag="VXB18_000015"
     CDS             complement(13623..13796)
                     /locus_tag="VXB18_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381315.1"
                     /translation="MTKVKFGVTSVDYSASIEDTPTIKLGLIIRGSGRLDASSVIKKL
                     IKDVSELEYELEE"
     gene            complement(13783..15351)
                     /locus_tag="VXB18_000016"
     CDS             complement(13783..15351)
                     /locus_tag="VXB18_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0381316.1"
                     /translation="MSLFQKVKDFFSRGRYYMQTSNLNSILEHPKIAVTQEEYDRIKR
                     NLVYYQSKWDDVQYKNTDGDIKSRPMNHLPIARTASKKIASLVYNEQATITTKNEILQ
                     KFLDDMLTNDRFNKNFERYLESCLALGGLAMRPYIDGDKVRVAFIQAPVFFPLESNTQ
                     DVSSAAILTKTIKSEGRKNVYYTLVEFHEWVTADGQETGSTNDKKYYRITNELYRSDV
                     NDVLGQRVNLSELDKYKNLEPVTVFENLSRPLFTYLKTPGMNNKDINSPLGLSIFDNA
                     KTTIDFINRSYDEFMWEVRMGQRRVIVPEHLTQRQYQRPDGTIDFRPRFDVEQNVYMQ
                     IGGSSMDAGGITDLTSPIRANDYILAISEGLKLFEMQIGVSSGMFTFDGQGMKTATEI
                     VSENSDTYQMRSSIVALVEQSIKELCVSMCELGKAVGVYSGEIPELDDISVNLDDGVF
                     TDRHAELDYWAKMVAAGFSTKKRAIGKTLNISGVEAEKELNAINSELLPMNDAELAIY
                     GMYDQNEEEEDDKG"
     gene            complement(15364..16674)
                     /locus_tag="VXB18_000017"
     CDS             complement(15364..16674)
                     /locus_tag="VXB18_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0381317.1"
                     /translation="MTFNVQKNINPHFKSVWISSLPYNVLKGGRNSFKSSVIVLKLAY
                     MMIRYIIAGEAANIVVIRKVANTIRDSVFNKVWWALNLFGIAEQFTKTVSPFKIVHKT
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFNDQEDFDQSNVTFMRQKHPRAKF
                     VQFFWSYNPPRNPYSWINEWFESIKTNKNYLAHSSTYLDDELGFVTEQMLEDIERIKE
                     NDYDYYRYLYLGEAVGLGNNVYNMSMFHAIDALPSDDKLIGISFALDGGHQQSATACC
                     AFGITAKGKVILLDTWYYSPAGQVVKKAPSQLSKEIYAYMRSVIEKYRVQALQYTIDS
                     AEGALRNQMFLDFGLKWHPVAKLRKVTMIDSFQSLLAQGRFYYLNTENNKIFIEEHKM
                     YRWDEKTIKSDNPSVIKEDDHTCDTTQYFVLDNAKLLGLRVGNV"
     gene            complement(16664..17119)
                     /locus_tag="VXB18_000018"
     CDS             complement(16664..17119)
                     /locus_tag="VXB18_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein"
                     /protein_id="HEV0381318.1"
                     /translation="MPRDGTKNLKPVTERTKDEARAISSKGGKASGIARRKKADLKKA
                     FEILLSLDVTDSKIKKQLEEMGMAGNNEALLAFATFQQAVKGNQKATENIIKLTNTKD
                     KYDIQEQKERIKALKYENRERAEAEKGSSETIEIVDAWAEDVRGATDDL"
     gene            complement(17323..18069)
                     /locus_tag="VXB18_000019"
     CDS             complement(17323..18069)
                     /locus_tag="VXB18_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381319.1"
                     /translation="MAQKLTKLKDIFKHVSSIDLGKEILFEDLELYNKETETSKQYQS
                     IEEAENDLSLMEKVNKINFTLGGGRGANFEKGKDGKYPGFRGAGGARDSGSSKALHPA
                     SLNNQGRFSSVEGTIQEFIKKHGGSRTEYSTAVDSQGFAHNYVHGGKNSVQILPISGG
                     FTAIHNHPNGSNFSSTDLHSFAALKGMNTLVATNSSKAYRITKGANFDAKGFDKAVSK
                     SRFTTKDYNKGADLWLKKNAKKYGYTYSYE"
     gene            complement(18050..19144)
                     /locus_tag="VXB18_000020"
     CDS             complement(18050..19144)
                     /locus_tag="VXB18_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4417 domain-containing protein"
                     /protein_id="HEV0381320.1"
                     /translation="MEMLQIEYVDIKSIKPYHKNARHNDGEATEKVAASIKAFGFQQP
                     ILVDDNNIIITGHTRLKAALSLGIDTIPIAHAVNLTDEQIKAYRLADNRVAEYSTWDS
                     ELLNIELSQFETIDMAQFGFELSVTGFNFGNEEEQQEETENEEEDAEDFHRDTTINQY
                     NLFHYDDTRVEGFYNMPKIEGVDHIPKDFQGFNYVLNKPDYSSCVHFFLDDYQFERIW
                     QRPDFYIEKLLEFDSALAPDFSLYLDMPIAMQVWNIYRSRLIGQIMQDYGLTVIPTVS
                     WASEESFDFCFDGLPKNSTLAISTIGVKQNKEQFEVWKNGVTEMIKRLTPKRIVVYGG
                     KVEYDYKDIEVVYFENATTERMKESGTKTN"
     gene            complement(19210..19602)
                     /locus_tag="VXB18_000021"
     CDS             complement(19210..19602)
                     /locus_tag="VXB18_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381321.1"
                     /translation="MTKKKIERLSVIHRREINWLKWYFLRDKKNPKRTILEQKIIVSH
                     IKTDRLEAKFLSNLKKSTEDFIDKSDPKYLRAIKEVYVYENMNVIGACQKILFYSPTQ
                     AYVLLNAWFNDYFRATYTELLENAILDK"
     gene            complement(19602..19895)
                     /locus_tag="VXB18_000022"
     CDS             complement(19602..19895)
                     /locus_tag="VXB18_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381322.1"
                     /translation="MTQTLEQAAKAESERIKIPKEIRPSDVGYRIVNKHGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEEVIHD"
     gene            complement(19916..20287)
                     /locus_tag="VXB18_000023"
     CDS             complement(19916..20287)
                     /locus_tag="VXB18_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381323.1"
                     /translation="MRPCKYPFLGRRKKQETSSPLFSARPIFNEVPIMEEVKVELGVE
                     AKIGRSYPEMLIHLDISGYGNRVHSVHRFPGIFLTVGESIQLKILFYKRIRNLTADHF
                     LTFRESDWKFLISDLVNEFVR"
     gene            complement(20284..20496)
                     /locus_tag="VXB18_000024"
     CDS             complement(20284..20496)
                     /locus_tag="VXB18_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381324.1"
                     /translation="MTKFVKIQSCYRGHTDDELINIDDISRLCLGPNILFLRTPYNLG
                     EHHISITQNSVDKLLKVLDIIGEDGK"
     gene            complement(20497..21081)
                     /locus_tag="VXB18_000025"
     CDS             complement(20497..21081)
                     /locus_tag="VXB18_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0381325.1"
                     /translation="MNKDLIETPRFNFFIGDEVLLKGKIVGFDVDENKCVENVVRLEY
                     GQTLNVPNNNIYITDDIVDKSKIKVVVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDK
                     KVPDWFYENNIEKFCLAWLNGYEVEKEKRYFVKIKGNIKGNMLVYGELLKRYFFTKNF
                     SLDNVIYSHTRKELEDANFGWVFDCPGIEIEEVE"
     gene            complement(21074..21484)
                     /locus_tag="VXB18_000026"
     CDS             complement(21074..21484)
                     /locus_tag="VXB18_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381326.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMNKDKGRAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGGLSEEKGHYRLEFDIEEVENE"
     gene            complement(21495..21707)
                     /locus_tag="VXB18_000027"
     CDS             complement(21495..21707)
                     /locus_tag="VXB18_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381327.1"
                     /translation="MSDYKQRMIEEYKQLKERTNKLSLMISNYYVGTLDFKLKCPIEL
                     LETQHYTMCAYLKILEQRAEIENIEF"
     gene            complement(21724..22461)
                     /locus_tag="VXB18_000028"
     CDS             complement(21724..22461)
                     /locus_tag="VXB18_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381328.1"
                     /translation="MTTENLKSALEYAVELNEHGLEILTAADGTEYYDANKFNLKELD
                     PKRYPKTLELSTLTSLVDYLKTDLNNLKNQRLIVAVEKNDEVCVWSENDELERRTLLV
                     DVKARIPELSFGRFLSSEQFNIMLQSNFIDDNDRGTLLEFASALKIENGAEIEDNGVS
                     QVATVKTGVASLAKGKAPNPVTLRPYRTFSEVEQPASLFVFRIDKQANMALFEADGKR
                     WVADAVGNIAAYLKEQLADQKHITVLA"
     gene            complement(22463..22897)
                     /locus_tag="VXB18_000029"
     CDS             complement(22463..22897)
                     /locus_tag="VXB18_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381329.1"
                     /translation="MDKKLIGLDLTHIADGGLQEKLDKELEKVFDNILDLNTDAKAKR
                     KVTITLTMSANEERTVVDTAMEVKSKFAPQNGVATTILIGRDFDTGQVHANELKSTVP
                     GQMYFDENGEILTDIGQPVAEIEQQAETKSDIIDFNKKKVGN"
     gene            complement(22951..23154)
                     /locus_tag="VXB18_000030"
     CDS             complement(22951..23154)
                     /locus_tag="VXB18_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381330.1"
                     /translation="MTKIEIVMVLTTLMSITWAAIVTIHTMQAIKKHKAKVDYYQKPQ
                     VQCEIARHVLKNKWYSDGGEVFR"
     gene            complement(23189..24337)
                     /locus_tag="VXB18_000031"
     CDS             complement(23189..24337)
                     /locus_tag="VXB18_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0381331.1"
                     /translation="MKFLDLFAGIGGFRIGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGHVDVICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILKPRYLFLENVKGLLNHDRGNTFEVILSALDELGYDVEWQVLNSKNFGVPQNRER
                     VFIIGHLRREHTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIRVKE
                     ATKQGYQEAEIGDSVNLSHPNSKTRRGRVGKQIANTLLTGESQGVVEPDFRIRKLTPR
                     ECWRLQGFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN"
     gene            complement(24351..24635)
                     /locus_tag="VXB18_000032"
     CDS             complement(24351..24635)
                     /locus_tag="VXB18_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381332.1"
                     /translation="MEFIKVKVDLQCPFCGNCKVVKVGAHRKAITCPSCKQAVFLSWA
                     TGIEGETDEHGYYFHAVEPFNIRKINQEFQDAFEDAPPKHSFTIRNKMRG"
     gene            complement(24649..25224)
                     /gene="ssb"
                     /locus_tag="VXB18_000033"
     CDS             complement(24649..25224)
                     /gene="ssb"
                     /locus_tag="VXB18_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0381333.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQSAENLVNWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQGSSFQNGNNQGNNFQNGNSYGQQGSFFEGN
                     TTNLVPDFTRDNNPFGRPTNPLDISDDDLPF"
     gene            complement(25214..25390)
                     /locus_tag="VXB18_000034"
     CDS             complement(25214..25390)
                     /locus_tag="VXB18_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381334.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTGLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            complement(25412..26404)
                     /locus_tag="VXB18_000035"
     CDS             complement(25412..26404)
                     /locus_tag="VXB18_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0381335.1"
                     /translation="MVKDVTNSLTEIKVDFQPAVINVDREAIEAQVAAAIAQYSGREV
                     TIDNYKEVYEERTRFNKLIGGLDTQRKDFNRQINEPAKDFDKWVKEKVIKPIEGVTDA
                     MSAGLNAIDEHERLMRVDVVRATFEDKCMVAGIEKSTFADKYDEYSLKKYFKTGKYEL
                     KKTTLDEMDGLVLSEFDALEEYKANKQAIQEQAQEYDLPADSYIRHLEDGKSLVDILK
                     MMKTDRDAEIARKEQKEAQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTI
                     TPEPQNNAREVAKFEPSEPLVKLVRLELHGGLEQWENTQEYFEDNFIGFETLED"
     gene            complement(26407..27108)
                     /locus_tag="VXB18_000036"
     CDS             complement(26407..27108)
                     /locus_tag="VXB18_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEV0381336.1"
                     /translation="MADLTFAELQRKMQIEKQTKQGVKYPFRTAEDINNKFKSLDSGW
                     SVSFPEDDIIQKGDKLYYKAVAVAKRESDGTIEKAIGWAREEDVPIFHTQKGDVKQMQ
                     DPQWTGAVGSYARKYALQGLFAIGGEDVDEYPVEESQEQGQNNQQQKPNNQQAQGQNQ
                     VRYIDNTQYQEINDLINDIAKIKGMPFDTLANYVLSEKLKGLQDFHRVQVGDYEVLKN
                     YLTEQLAKAKAKRGN"
     gene            complement(27114..27566)
                     /locus_tag="VXB18_000037"
     CDS             complement(27114..27566)
                     /locus_tag="VXB18_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381337.1"
                     /translation="MPNWAEGTLKLRGRRENVASALKEMLLGNKGATLEEEYDGTLLR
                     FKNEYDYFYINGTRRAFISSKDIEIWLDDDFVIIELEDFKQAWAALADNYTEISSKFD
                     VDIKIFTFEMGMEFTQEIEISKGEIIKNIVNENFTNYSWDVPFSRLGG"
     gene            complement(27649..27915)
                     /locus_tag="VXB18_000038"
     CDS             complement(27649..27915)
                     /locus_tag="VXB18_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381338.1"
                     /translation="METVQIVRIKDVIIEKISANDEELERIFGCSKRQAGDMRREMKK
                     LPSQQKYLRNDGQLVTIKGFDAYLQYRGSQPWKKEMAKTVKMTR"
     gene            complement(28072..28413)
                     /locus_tag="VXB18_000039"
     CDS             complement(28072..28413)
                     /locus_tag="VXB18_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0381339.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVNRKTIDKYFKIFEEAGYLRK
                     IRKKPPGNGGSHIFRFFSDVKISDFQFDIMKQRLNLSIKRASMNYNSDIPKSEMSESE
                     MSESEMSDFGH"
     gene            complement(28599..29306)
                     /locus_tag="VXB18_000040"
     CDS             complement(28599..29306)
                     /locus_tag="VXB18_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEV0381340.1"
                     /translation="MNEVIKVTVNDNHEPIVSGRQLHEALGVKTEYRKWFGRMAEYGF
                     EENQDFARVTQKCPTPGGLQDMTDHIIKLDMAKEIAMIQRTDKGKEVRQYFIQVEKDF
                     NSPEKIMARALLMADQKVHKLEAQIEADKPKVLFADAVSASHTSILVGELAKLISQNG
                     YKIGANRLFSWMRENGYLIKRKGSDWNMPTQRSMDLKLFEIKETNVQHADGHITVNKT
                     PKVTGKGQQYFIDKFLN"
     gene            complement(29318..29527)
                     /locus_tag="VXB18_000041"
     CDS             complement(29318..29527)
                     /locus_tag="VXB18_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015997031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0381341.1"
                     /translation="MSQQHLKWIELVKERIEKRGWSQTDLATVVGVSPSAITQLLKDG
                     KGSDDLKLRINKKLRINESWERFEE"
     gene            29637..29729
                     /locus_tag="VXB18_000042"
     CDS             29637..29729
                     /locus_tag="VXB18_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0381342.1"
                     /translation="MMELILKTIIGPIVVGVVLRLADKWLNKDK"
     gene            30129..30488
                     /locus_tag="VXB18_000043"
     CDS             30129..30488
                     /locus_tag="VXB18_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0381343.1"
                     /translation="MFPTYEKIKELADKHGISLMKLEEDLGYSRNTLYKLKSQKPNAE
                     RISEIADYFNVSTDYLLGRTDNPTIANKKEQFFFEGKEVDVEELASTAMRFNGKPLTE
                     EDKKAIQNIIEIYLRKQ"
     gene            30510..30890
                     /locus_tag="VXB18_000044"
     CDS             30510..30890
                     /locus_tag="VXB18_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0381344.1"
                     /translation="MTEKEFSQNLGIDIEIFEDGLFPDEAFYIPALKTMFLSDAISDE
                     KRVQVALHEIGHRNHAPDTYQLFREKCELEANRNMIHHLMKAELDIAEDATTFNYLVF
                     MEKYNLKTIADEIMVKEEYLALLN"
     gene            30904..31254
                     /locus_tag="VXB18_000045"
     CDS             30904..31254
                     /locus_tag="VXB18_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381345.1"
                     /translation="MNIIAIIIIVIFVGGVIGAVIDNQKKSPEQRERELETFRANQEK
                     KKQEKKQNIITCPNCKSKDVTFLQQDKKAFSVGKAVGGAVLTGGVGALAGFAGKKGNK
                     QWHCQNCGNFFETK"
     gene            31373..32515
                     /locus_tag="VXB18_000046"
     CDS             31373..32515
                     /locus_tag="VXB18_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0381346.1"
                     /translation="MWMEELSNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIE
                     GDYLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFV
                     ETPRKVITSDELRKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMR
                     YGELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQ
                     IIENATNGFDTDFIFINTLGEPITNARVICALKRHGQKIGIEKNITTHTFRHSHISLL
                     AELGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLDKIKF"
     gene            complement(32606..32881)
                     /locus_tag="VXB18_000047"
                     /pseudo
     CDS             complement(32606..32881)
                     /locus_tag="VXB18_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(32992..33246)
                     /locus_tag="VXB18_000048"
     CDS             complement(32992..33246)
                     /locus_tag="VXB18_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381347.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(33586..34032)
                     /locus_tag="VXB18_000049"
     CDS             complement(33586..34032)
                     /locus_tag="VXB18_000049"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0381348.1"
                     /translation="MDETGIDRYLYRPYARAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNASFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDVLREVSTIFECLECFFKTR"
     gene            complement(34105..34431)
                     /locus_tag="VXB18_000050"
     CDS             complement(34105..34431)
                     /locus_tag="VXB18_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0381349.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            34665..36383
                     /locus_tag="VXB18_000051"
     CDS             34665..36383
                     /locus_tag="VXB18_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0381350.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            36494..36841
                     /locus_tag="VXB18_000052"
     CDS             36494..36841
                     /locus_tag="VXB18_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0381351.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(37120..37956)
                     /locus_tag="VXB18_000053"
     CDS             complement(37120..37956)
                     /locus_tag="VXB18_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0381352.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(37969..38598)
                     /locus_tag="VXB18_000054"
     CDS             complement(37969..38598)
                     /locus_tag="VXB18_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0381353.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(38608..39249)
                     /locus_tag="VXB18_000055"
     CDS             complement(38608..39249)
                     /locus_tag="VXB18_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0381354.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(39395..40624)
                     /locus_tag="VXB18_000056"
     CDS             complement(39395..40624)
                     /locus_tag="VXB18_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0381355.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(40614..41780)
                     /locus_tag="VXB18_000057"
     CDS             complement(40614..41780)
                     /locus_tag="VXB18_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0381356.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            41924..42937
                     /locus_tag="VXB18_000058"
     CDS             41924..42937
                     /locus_tag="VXB18_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0381357.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(42982..43401)
                     /locus_tag="VXB18_000059"
     CDS             complement(42982..43401)
                     /locus_tag="VXB18_000059"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0381358.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(43412..44818)
                     /gene="atpD"
                     /locus_tag="VXB18_000060"
     CDS             complement(43412..44818)
                     /gene="atpD"
                     /locus_tag="VXB18_000060"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0381359.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(44904..45782)
                     /locus_tag="VXB18_000061"
     CDS             complement(44904..45782)
                     /locus_tag="VXB18_000061"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0381360.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(45798..47303)
                     /locus_tag="VXB18_000062"
     CDS             complement(45798..47303)
                     /locus_tag="VXB18_000062"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0381361.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(47318..47854)
                     /locus_tag="VXB18_000063"
     CDS             complement(47318..47854)
                     /locus_tag="VXB18_000063"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0381362.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(47854..48348)
                     /gene="atpF"
                     /locus_tag="VXB18_000064"
     CDS             complement(47854..48348)
                     /gene="atpF"
                     /locus_tag="VXB18_000064"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0381363.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(48362..49078)
                     /gene="atpB"
                     /locus_tag="VXB18_000065"
     CDS             complement(48362..49078)
                     /gene="atpB"
                     /locus_tag="VXB18_000065"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0381364.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(49113..49313)
                     /locus_tag="VXB18_000066"
     CDS             complement(49113..49313)
                     /locus_tag="VXB18_000066"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0381365.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(49388..50395)
                     /locus_tag="VXB18_000067"
                     /pseudo
     CDS             complement(49388..50395)
                     /locus_tag="VXB18_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(50901..51251)
                     /locus_tag="VXB18_000068"
     CDS             complement(50901..51251)
                     /locus_tag="VXB18_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381366.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSL"
     gene            51379..51456
                     /locus_tag="VXB18_000069"
                     /pseudo
     CDS             51379..51456
                     /locus_tag="VXB18_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(51624..52106)
                     /gene="greA"
                     /locus_tag="VXB18_000070"
     CDS             complement(51624..52106)
                     /gene="greA"
                     /locus_tag="VXB18_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0381367.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(52177..53832)
                     /gene="mltG"
                     /locus_tag="VXB18_000071"
     CDS             complement(52177..53832)
                     /gene="mltG"
                     /locus_tag="VXB18_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0381368.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVSTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(53913..54407)
                     /locus_tag="VXB18_000072"
     CDS             complement(53913..54407)
                     /locus_tag="VXB18_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381369.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(54404..54868)
                     /locus_tag="VXB18_000073"
     CDS             complement(54404..54868)
                     /locus_tag="VXB18_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381370.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEMAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(54878..56212)
                     /locus_tag="VXB18_000074"
     CDS             complement(54878..56212)
                     /locus_tag="VXB18_000074"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0381371.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(56223..56840)
                     /locus_tag="VXB18_000075"
     CDS             complement(56223..56840)
                     /locus_tag="VXB18_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0381372.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(56888..59986)
                     /locus_tag="VXB18_000076"
     CDS             complement(56888..59986)
                     /locus_tag="VXB18_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0381373.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNMAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(60079..61245)
                     /locus_tag="VXB18_000077"
     CDS             complement(60079..61245)
                     /locus_tag="VXB18_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0381374.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(61253..62347)
                     /locus_tag="VXB18_000078"
     CDS             complement(61253..62347)
                     /locus_tag="VXB18_000078"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0381375.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(62504..63049)
                     /locus_tag="VXB18_000079"
     CDS             complement(62504..63049)
                     /locus_tag="VXB18_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381376.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     IDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            complement(63085..63624)
                     /locus_tag="VXB18_000080"
     CDS             complement(63085..63624)
                     /locus_tag="VXB18_000080"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381377.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            complement(63633..64178)
                     /locus_tag="VXB18_000081"
     CDS             complement(63633..64178)
                     /locus_tag="VXB18_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381378.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            complement(64350..66308)
                     /locus_tag="VXB18_000082"
     CDS             complement(64350..66308)
                     /locus_tag="VXB18_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0381379.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(66511..68133)
                     /locus_tag="VXB18_000083"
     CDS             complement(66511..68133)
                     /locus_tag="VXB18_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0381380.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            68239..69684
                     /locus_tag="VXB18_000084"
     CDS             68239..69684
                     /locus_tag="VXB18_000084"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0381381.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QQPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(69730..69912)
                     /locus_tag="VXB18_000085"
     CDS             complement(69730..69912)
                     /locus_tag="VXB18_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0381382.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGLKNVFTK"
     gene            complement(70013..70608)
                     /locus_tag="VXB18_000086"
                     /pseudo
     CDS             complement(70013..70608)
                     /locus_tag="VXB18_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(70645..71157)
                     /locus_tag="VXB18_000087"
     CDS             complement(70645..71157)
                     /locus_tag="VXB18_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0381383.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(71244..72179)
                     /locus_tag="VXB18_000088"
     CDS             complement(71244..72179)
                     /locus_tag="VXB18_000088"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0381384.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(72250..72549)
                     /locus_tag="VXB18_000089"
     CDS             complement(72250..72549)
                     /locus_tag="VXB18_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0381385.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(72539..73288)
                     /locus_tag="VXB18_000090"
     CDS             complement(72539..73288)
                     /locus_tag="VXB18_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0381386.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(73342..73701)
                     /locus_tag="VXB18_000091"
     CDS             complement(73342..73701)
                     /locus_tag="VXB18_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0381387.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(73703..75103)
                     /locus_tag="VXB18_000092"
     CDS             complement(73703..75103)
                     /locus_tag="VXB18_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0381388.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(75398..75637)
                     /locus_tag="VXB18_000093"
     CDS             complement(75398..75637)
                     /locus_tag="VXB18_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0381389.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(75669..76139)
                     /gene="ssbA"
                     /locus_tag="VXB18_000094"
     CDS             complement(75669..76139)
                     /gene="ssbA"
                     /locus_tag="VXB18_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0381390.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(76151..76441)
                     /locus_tag="VXB18_000095"
     CDS             complement(76151..76441)
                     /locus_tag="VXB18_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0381391.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(76594..77940)
                     /gene="asnS"
                     /locus_tag="VXB18_000096"
     CDS             complement(76594..77940)
                     /gene="asnS"
                     /locus_tag="VXB18_000096"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0381392.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(77956..78321)
                     /locus_tag="VXB18_000097"
     CDS             complement(77956..78321)
                     /locus_tag="VXB18_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0381393.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(78314..79501)
                     /locus_tag="VXB18_000098"
     CDS             complement(78314..79501)
                     /locus_tag="VXB18_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0381394.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVAPNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEKRLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(79498..79986)
                     /locus_tag="VXB18_000099"
     CDS             complement(79498..79986)
                     /locus_tag="VXB18_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0381395.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            80307..80855
                     /locus_tag="VXB18_000100"
     CDS             80307..80855
                     /locus_tag="VXB18_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0381396.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLAADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLIEAIK"
     gene            complement(81132..81860)
                     /gene="yaaA"
                     /locus_tag="VXB18_000101"
     CDS             complement(81132..81860)
                     /gene="yaaA"
                     /locus_tag="VXB18_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0381397.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(81939..82103)
                     /locus_tag="VXB18_000102"
     CDS             complement(81939..82103)
                     /locus_tag="VXB18_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0381398.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(82170..83765)
                     /locus_tag="VXB18_000103"
     CDS             complement(82170..83765)
                     /locus_tag="VXB18_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381399.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(83777..84187)
                     /locus_tag="VXB18_000104"
     CDS             complement(83777..84187)
                     /locus_tag="VXB18_000104"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0381400.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(84303..85094)
                     /gene="yghU"
                     /locus_tag="VXB18_000105"
     CDS             complement(84303..85094)
                     /gene="yghU"
                     /locus_tag="VXB18_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0381401.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(85107..87803)
                     /locus_tag="VXB18_000106"
     CDS             complement(85107..87803)
                     /locus_tag="VXB18_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0381402.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            88107..89291
                     /gene="mntE"
                     /locus_tag="VXB18_000107"
     CDS             88107..89291
                     /gene="mntE"
                     /locus_tag="VXB18_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0381403.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(89434..91305)
                     /locus_tag="VXB18_000108"
     CDS             complement(89434..91305)
                     /locus_tag="VXB18_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0381404.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQIKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(91302..92486)
                     /locus_tag="VXB18_000109"
     CDS             complement(91302..92486)
                     /locus_tag="VXB18_000109"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0381405.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKDIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(92498..93265)
                     /locus_tag="VXB18_000110"
     CDS             complement(92498..93265)
                     /locus_tag="VXB18_000110"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0381406.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELITGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(93542..94390)
                     /locus_tag="VXB18_000111"
     CDS             complement(93542..94390)
                     /locus_tag="VXB18_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0381407.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(94392..94766)
                     /locus_tag="VXB18_000112"
     CDS             complement(94392..94766)
                     /locus_tag="VXB18_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0381408.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(94840..96192)
                     /locus_tag="VXB18_000113"
     CDS             complement(94840..96192)
                     /locus_tag="VXB18_000113"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0381409.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKKTGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(96216..96995)
                     /locus_tag="VXB18_000114"
     CDS             complement(96216..96995)
                     /locus_tag="VXB18_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0381410.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(96982..97839)
                     /locus_tag="VXB18_000115"
     CDS             complement(96982..97839)
                     /locus_tag="VXB18_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0381411.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERW
                     LGGWKHEKK"
     gene            97975..98943
                     /locus_tag="VXB18_000116"
     CDS             97975..98943
                     /locus_tag="VXB18_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0381412.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(99196..100152)
                     /gene="lytA"
                     /locus_tag="VXB18_000117"
     CDS             complement(99196..100152)
                     /gene="lytA"
                     /locus_tag="VXB18_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0381413.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGFYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGSMADKPEFTVEPDGLITVK"
     gene            complement(100156..100488)
                     /locus_tag="VXB18_000118"
     CDS             complement(100156..100488)
                     /locus_tag="VXB18_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0381414.1"
                     /translation="MQQITEIIIAFATSFLTVAVGGIVKAVKDYLLRKGGEKAVIIAE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(100492..100908)
                     /locus_tag="VXB18_000119"
     CDS             complement(100492..100908)
                     /locus_tag="VXB18_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0381415.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            complement(100917..101267)
                     /locus_tag="VXB18_000120"
     CDS             complement(100917..101267)
                     /locus_tag="VXB18_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381416.1"
                     /translation="MAETNQNTDNLLDLTKITEPFELASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            complement(101270..101473)
                     /locus_tag="VXB18_000121"
     CDS             complement(101270..101473)
                     /locus_tag="VXB18_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381417.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(101454..101570)
                     /locus_tag="VXB18_000122"
                     /pseudo
     CDS             complement(101454..101570)
                     /locus_tag="VXB18_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
     gene            complement(101567..>101877)
                     /locus_tag="VXB18_000123"
     CDS             complement(101567..>101877)
                     /locus_tag="VXB18_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0381418.1"
                     /translation="KYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDFIENKKHE
                     EIGLIAQEAETIVPKIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA
                     "
BASE COUNT        29093 a        22601 c        18257 g        31926 t
ORIGIN      
        1 tccccgtgca caccaataac agtaggctct gttgtcttac ttgtaccgtt tgtgtatagc
       61 tcaactcgat aattccataa ataacgcttg tctgatgtga taggctgtgg cgtagttgtc
      121 caccctgcgc ttgttcttgt gatacctgtt gagactgtag tagctaaata ataattagtt
      181 acattagaaa taccagtacc atctgcccct tttatcaacg tccacttata cactctgtaa
      241 tctgtgctat ctgcctgagt gtaatctgtg tatgttccga tatacgtttt atttgtactg
      301 tcagtagttg aaaaaccttg tgatccatta tttgatgtgg cgtaagctat gtgtaagtat
      361 ggtgtcctac catctgtacc agccttacct gccacgccgt ttgcgccatc agctcctttt
      421 acaagtgtcc aattgtaatc agatggagta ttactatcag cactattaaa atcaacatac
      481 ataccgatat aagctctatc agaggcgctt acagaaaaat ccttagttcc atcagcgcta
      541 ttgctgtaag ctatgtgagt gtattgagta cggccatctg caccattgcg accaggtaat
      601 ccttgttcac ctcttgcacc ttgcaagcca tctaaaccac gttgtcccgg ttctccttta
      661 tctccttttt ctcccttgtc tccttttact ttagcccact tgtatttttt agggtctgtg
      721 ctatcgtttg gttcaaagtc tgtataaata ccaatataga gtttattgat tgagctatca
      781 agactaaatc catctgttcc tgttgcatta ttagcccatg ctgtattgac ataaggagta
      841 cggccatctc gccctggagt tccaggtgta ccaagttttc catcagcaac attaacaagc
      901 gatatctcat caacagcaac ctctttattt ccaatgtaag ctgcaactgt cagagtaact
      961 gtatcagtta catttgagcc tctaactaag taagtcatcc ctgttgttac ttctccatca
     1021 agtgcccatc gccaagtaac accaacaacg actggttttc ctcccttgta taaggttggg
     1081 gttactagac tctggccgat ctgattttta aagataacac cattgtccgt tgataatttg
     1141 atagtatatg gtttagcagc ttcaaacaat ctctcaaagg ctgactggat atcagctgat
     1201 agtttgtttt caagtgcctt gaaattgtca aatattgtct tatttctcac tggatttgtg
     1261 aaactgattt tttgatcagt aacccgtgct tgaatcatca atagaggggc aaaaccgtca
     1321 tcatggactt taacagtatc tccaatatca gcatcgacaa agccatcaac ttcataagtg
     1381 atagctggat aacaatactt tttcaatttg agataaccta aacgtcttaa ctcgtttggc
     1441 tcatctgttt caaaatgaaa atcttttctt gtccactggt caagctcccc tgttgaatga
     1501 gtaaaggttg agggatatag ttgcattgaa ataggcgcat acagtgcttg ccctctttga
     1561 taaaattcaa ctatcccttt ctcgttcttt acttcccatt catccaatcc ctcaatcgtc
     1621 aaaacatcct cagttgtatt tgttttttct tttggatttg gttttttcaa gacttttgtt
     1681 tcagacgttg atgctccgcc ttttttgctg gttgtaacag tttgttctat ggaaccatca
     1741 gaacgagtcg ttgtggtcgt tgtgatccgt gtcttgtccg ctaactttgt aactttagtg
     1801 tggacaatag ttttgctctt agtcccatct gaggctgtag agattgtggt tttcgtcgtt
     1861 gaaccatctg cattttttac agtttcgctt ttggagccct tatctccgct cagttcttct
     1921 tcaaccgttg gcattttacc agtcggtctg attgtattga aaataccagt cttatccact
     1981 tttcttgtaa tagagtggat gttttttccg tatttaacaa tgacatcatt tcttacacgt
     2041 cccacccctt gatggttgtc atcgttttca tgataaacat taacactaaa ctttttgata
     2101 gtgctatcag catttaactg tgtatcaaat tcaatctcag catcaaatcg tttggctagg
     2161 cttaatagac gggctagttt ggtttcttgc ccctcccatt ccagagtacg cttataatct
     2221 gatatttcat tgataccaat agaaaggtga gtataattta aaagatccat cgcctcacaa
     2281 tactctttga aagtcatcgc tttgttagat ttataagggt tcgcaagctc attgattaac
     2341 tcaagattga gattttcaca ataacatttg attgtctgct cattttcttc aacaataatg
     2401 atattaaaca caaagctttt acccttgtac ttaaatgaga caaatgcatg ctcattcaaa
     2461 tgatgatagg ctttagcaag aggtaaatca gactttacag cctttttaaa taccgtaaac
     2521 tcaaacgttg acgaacctgt tgcaagactt cttgtccaag tatcatcgta ataatttaac
     2581 gtaccttgtt tttcgttatc aataaatgct accttttgta aatttgcatc atggattgtc
     2641 aaaagcatct tatatccacc tttcttcaaa ttcgattgtt acagttggtt ttttcttaac
     2701 aaaacgtgaa aaatacaact ctagttgaga ttttcctgga ggaattgctg gccaatgtga
     2761 accgtctaca acttcgctta ctttagatat cccgtcaata tacacactat cgtcctcact
     2821 gttgattaca acatttgaac ctattggata gcgattagga atatctctac tctttgtcac
     2881 aaagtctttt ctatacatga actcatcaac atacatatgt gatacaagag gccagtctct
     2941 gagtgctcca agcgtgatat ggatttttgc tgattttttg tcttttatct ccggaataat
     3001 aaagtcataa tgagagccat caaaaaacac ttgaactcta tcatcgtttc tttttaactc
     3061 tgaccagccc ttttccgcgc taaatggatc aagtttgcct acttgagccc ctgtcccagt
     3121 aaaataccac catttgataa acttgtatcc acctttgccg tcagtggtga aaaaactata
     3181 ctcacaatca agtgtctgat agcgtttgta agtttccacc ccatacaaga aattgccgtc
     3241 tgtatccgat acagtaacct ttatgaaacc atattgatta gcgactgctg ccataaaaac
     3301 ttgtctccaa agcagatagt cattcaatga accaacttct ccactactat caacaggaat
     3361 agcccatgtc aaactttgtg cattatttcg atttttttca actgtaccac ggtttgataa
     3421 ttcgatatga ttacgccccc acatacttgt tgtactcaaa gtgccaacaa gacgctcctt
     3481 attatcattt gttacagcta ctcctttagt gccattttga aatcctttta gaatattagt
     3541 ccctctataa tctatcaatg tttcagagtc tctgtatttt tcagtatcag cctcttcacg
     3601 atttcctaac tcaaacgccg ctctgttgtt aacaactcca atatatccat tctctgagtt
     3661 gtgtttaatt ctaataattg gataagctgg ctctgttcct gtatttgtta aattaaatac
     3721 tatcctatcc ggtgcgcttg tttcatttgt atcgatatca aaatttttta aagtcgtgct
     3781 gtgagccact ccatcaggaa ttattatttt taactctgag cgctggaacc atcttgtcaa
     3841 attttctgga gtaatctcat ctaccggcaa ccccatatag tatttgtctg gctcatcgcc
     3901 ataagtaatc tttactggct ctaaaacgtt tagaatgcct gccaaatcat gctttaattg
     3961 ttccatttca attgcatttg tggttttgat gtcaaatttt atgatatgct ctttttctcc
     4021 aatcttaacc tgttggatat tcacgcccaa taagggagcg ttatcagttg atacgctcct
     4081 cttgttcccg atagggcgga taatatctgt tatacgaaag aatttagaca tatcaactcc
     4141 gttgaaagtc attatctttg tcatgacaat acccctttca tcctattatc tcgtcttagt
     4201 tgttccgatt gatatttagc aaatttatcg cctgttttgg cgactaaagt accatcgttt
     4261 aagtacattt catttggtcg tctaacggcc gtctcagcta catccagggc ttttttgagt
     4321 agttcgctag acttgtccat agtaactttg attttttcag ctattgtctg cttactactt
     4381 tgtttaacag tcacttgagc acctagtttc ttgtttaagc caagtgcaat ttctggtcta
     4441 gtatcaatca tcatgctttc ttttaatcgc aacattgatt tttcaacaac ccctgcatct
     4501 gcttcaatac caacagcgat accttgagga atgaaacgtc cgacttcatc acgcattgct
     4561 ctagatggcg agtgaatatc taatgcgctc ttgatggtcg cttttaccct ttcagcaatt
     4621 gaattagctg ttgccataac agaaccagag ccactccaaa gccctgcatt aagaccagac
     4681 atcgccattt caccaatgta cgtgaaatca ctctgcagac tatcaaatgg tttcttaatt
     4741 tgattggcta aattagtaac agatgataca ggttgattgg tacctttatc taccccctca
     4801 gctaaaccag tagtgataaa accaccatac tcattgaaaa cacgagatgg ggaattgata
     4861 tccatttcac ttgtaaagga ttcttttatg tcatttgcca tgtttttaga agcttcactt
     4921 gcaattttag ctccagcttt tataccatca ccaacacctt caggaatatt tttccctttt
     4981 tcagggaagt cagcagctgc aatttcctct tgtaagcttg aaacttgact ttgtacaata
     5041 cccttgattt tgtctgtgat acccaaagca cccgtatcca taccagcagt taagccattc
     5101 atagctgact caccaccttg agtaaagact tcgttcaatg ttgccaattt ttcgtctgat
     5161 gcattaacga gttcttgaac gtacaaccca ccttgaggcc ccatcgcttg caatttagct
     5221 aaaatcccct cgtttacccc acgttcggcc aatgtattga ggtttgttgc ccaattatta
     5281 accgcctctt ggtttttttg gaggttggca atcatttcat cgacactaat agctgacttc
     5341 atttgtatct gatcaaacat gttcgttgtg gtttcaagca actcattgta tttagagcgc
     5401 atatcatcaa ccgctttttg ttgagcttta gacatacctt cgtatgatat aacttgtcga
     5461 ttagatccat tttcggcagc agcagccatc gcttcagatg ccgcctgttg aacttgagac
     5521 gttttttcgt actcagtttg caattctgtc tgagtatttt ttagctcagt ttccttgtcg
     5581 ttgagttctt gcagtctttc tttacggaca ctatcgctaa cattggattc ttcattccat
     5641 tttttgcgtt gttcagctat cttctttagc tgttcgccaa tttcagcacg cttttgttcg
     5701 atatcaagca ggttcttctg ggatgtctcc catgttgatt ccgcctccat cgctgagata
     5761 cgagctttga tttggtcatt gttatgagac aaagaatcag tgtttttgtc atagactaga
     5821 ttcaatccac taacagaggc atttaaagca tcaatctttt tcttgagatt tttcttgtct
     5881 gctgctgtct tatttgtctt ttgtgataac tggacaattt cgtcagccaa tttttggtaa
     5941 gattctgtat taccttttac agactcaaga tttttttgac gttcttttgc gctttgttta
     6001 acagaatccg ttaattgatc cgtactcttg actaactcct cttgttctga tttgaggcgt
     6061 ttggtctcct cactatcggc agttagccat tgccacaacc ctaccaatgc cccaacagca
     6121 agacctacac cagcaacaac caaaccaatc gggccagtta aagcggtcag tgctgcttta
     6181 aatgcggtag ttgcagcagt cgcagcaata gtagcagcag tctgtaagct gatagagcca
     6241 gttagaaccc cataaagcaa attggatgct gtcaaagctc cgttattggc caagttagca
     6301 accatttgag cctttgttac tgagccacaa gtagcttggg cagctgtcat tagattgatg
     6361 atctgaatcg ctcctgtggc tgttgttttg aatgtctgcc aggaattaat taagtttttt
     6421 gttgctgtta tagcttcatt agcggcacgc atagccacca aagcagaaac caaactaata
     6481 ataactggtg tcaaagatga gattacagaa gctccagtac ccaaaatact aaacaaagtc
     6541 tgaaaaacag gtgtgctagc tttaattacg ttgacaataa caccaaaagc cgcattgatg
     6601 attactttca atgcatcgaa gttctcagca atcgtcttac ttgttgctgc ctttgttaaa
     6661 tcgtcaagag ccttgatagt attagctaca cctttaacaa ccgcattctt taagttccca
     6721 aaagatgtct ggatcccttt actgttagtt ttagcaagtt ctgcaaaacc accaacgcca
     6781 ccattcaatt caaccaattt gcttgaaaat tggttgaaag tgatacgccc ctcttttaat
     6841 gcagaataga aatcattctg agcagattgg ccagcaaaac cgaatgattc agcagtcttt
     6901 tgcaaagcat aaggcatggt ttcctgtaac gttttccaac tttgcatgtc aaccttacca
     6961 gctgataaca tctgactgaa ctgttgtaaa ccacggcttg catcagcact agaagatcca
     7021 gaagcaagaa aggcattatt aagagcaagt gttaaatctg ttgatttgtt tatatcgcca
     7081 gtaatcgagg taaggcgttg agctgtgcct accacttcat ttaaagtcgt aggcaaaccc
     7141 tcaatacctg ccgctagttt cttagttgag cgcgtgacat cttctgtact atgccccata
     7201 gcttgcatca ctcttggata actttcaaga gtatcaaaac gttgaatcgc tccgtccaag
     7261 gaatctgtta gaagatctac cgctttagat gccagtttaa aagcagcacc accaatcgca
     7321 aacttcttta gagaatcgct ccctctgtca cctttctgtg ccgttttatc taactcatcg
     7381 tttagaacct tgactttatt accatccaca tcgacaacga tggtaacttt tccatcagcc
     7441 attatcttct ccctcctttc ctaaactata tttagcttgt aatttacgca ttttattctt
     7501 atccccacca tattctggtt tccatgctcg gatttctata atctgttgca tgattgtgtt
     7561 atctggcaaa gcgttcaaaa gtgctttaaa ttctgtccat gtcaactcat tttgaacttt
     7621 caaaagattg atgccgtagg cttgtaaaaa actagcgtaa atgtactctg catcttgttc
     7681 aaaatcaatc aatttttctt gttcttcttc accttttgcc tttggcatgg gattgcctag
     7741 caaatcatac tgaacagttt ctttttcgat ccctagaaag tgttctttta tgtaaatcca
     7801 acaatctaca acctctttga tgtcgtataa ttcttggcca gttagcaaat ggacaatcaa
     7861 ctgagcttgt tctagacgcg tcatttcatc ctcttttagg atttcaaaga catctagaac
     7921 tttattaaaa gacaggtcta tgtcgtactc tttatcagca atagaaaaat ttgtgattaa
     7981 ggcatcattt aatttcatag acatattttt tacctgctat ttctttttgt tctttttttg
     8041 tttcttgttg ttcttgattg gagtgacttt tcccttgttt aaatagtgac tagcacgctc
     8101 tttcaccacc gttttgtgtt gctcagcaac ttcttccaac ttgtcatgca acatgattgc
     8161 ggtctgttct agagcgttat ttagggcgtt ataatctgga tatatagaat ataacttgtc
     8221 aaatgtaccg tcgccaaaaa taagatcata ttgaatctca agctgtttct tctccaattc
     8281 aatagcccca gcaactactt ctttagttac tccatcacgc tcaattttgt tattgatatt
     8341 tgcagatacc acatctaatt catattggac aaggcgacgt tttagttctt cttccatgtc
     8401 ataaaagcgc attaagctct cttgacttgt atcaaaccat agctctactt ctccgatttt
     8461 tactggaaat cctgtacgtt ttagttcaat ctgaatatct gtcatgtctt tactcctttt
     8521 cctgttgtta aaaagggcaa ggctcaatgc ccgcccttat caaaagctat tacccaatac
     8581 cagtctcttt tggcgttgag ttgtaagaaa gcttacatcc aaacgcctca tagtcagagg
     8641 cagcgccaga acctgctttg atttctgttg cagttgcagc tcccacccat tgtttcttcc
     8701 tgtcagaaga aacaaccttg tgccatagct tacggtcatc ccctgtcttg tacttcatcc
     8761 cagcaataag agcctgtgct ttatcgtctg gatcgtaagt gccctcaaag gtataagcac
     8821 cttttacgct gaccacggtt gtttcttcaa ctccatcacc gtcatagtat gcttgatcat
     8881 ctgttttctc gtctgtatca tctgatacgt ctgagatcca tttagcaagt tccaaccatg
     8941 tatcttctgt tgatggttca gttcctccat tgtatggagc tacaaaatgg ccacgtaggg
     9001 cgtttttttg tcttgtcatt gtttgttcct ctctattacg attttcgcca caatttcaat
     9061 tgtgtaataa taatagcctt gctcatcctt gcctttcatg gcaggcctgc tgacttccat
     9121 tcccatatat tcataagaat tattgtcact tggtaaaact aagtctatct ttgctagttc
     9181 tgaggtgact aaccaaatag tgtcattggc tactgagttc ttttttgcct ttacggcgat
     9241 ttcaaacggc aaagaaactt cttgtgtgcc atccatatac tctctatcca ctttcccgcc
     9301 tggtatctga ttgataacca gatcatcttt gtcatcctca aagtaatcaa agcgtggttc
     9361 aactggtaaa tttaaagtct tgatatgctt taaaagtaca ttttgaaagt cattctctcg
     9421 catcaaagtc ccattccttt cacaaaagct ctagcccatt cttcagcatg tttactagta
     9481 gcaacttgat cccatcgttt tcctgtacct ggagcggtat atctcctaaa ggtgacaatg
     9541 ccgtttgatc cgtaaaattg cgctctagca taaactgttc catagacaac agcatcacct
     9601 tgtccaacaa ttcggccaga agctctcaac tctccacccc tcaaggggat atattgctca
     9661 ttgtctagca agattttgct agcgactgca atctttcctc ttgtcatgga ttcgttcgaa
     9721 agtttctgtt tagctttctg caagtcaact ttaatggcga tactcattag atcacctcaa
     9781 tttcttgact gaatatctca ccatcataat agttagtttg aaatccatta attgtataat
     9841 ctcctatccc atcgtttact tttgcaccca tccaactgtt atcaactgtc acaaaagata
     9901 gcgagggata gaggtatata accccttgtt tttgccttga ttttgaattt cctgtaccag
     9961 tttttgaatt acctgtacca gtttttgaat tacgattacc agatcccccc actgatctat
    10021 caaaacgtac atttttaata gtcaacggtt ctgaatatac ttcatcccca taatcgtttt
    10081 tatcagctac tttttttatg gttaggacat cctttaacaa acgcttgtca atccctttta
    10141 ataaccgctt atcgatcata ggcaactcca acaactaggc taaagccggc ttgtctcaaa
    10201 gcattttcag catccataga caaattaaat cgctgacctg ctgatgtgct ttgtgaggtg
    10261 ctataagaga ttgatgtacg gccaatagag acactattgg ctagctgttt gtcatcggct
    10321 gacataatac cagaggcatc gagataggct atttggaatg ccatagcaag ctttacagca
    10381 gatttgcgat aggcaatttc tttttcaaaa tcaatgtctt tctgataaat accgttagtg
    10441 tataggtcaa tcgctatctt tgcccgtttt gccaattttt caaagtttgt aacttcatca
    10501 aaacctaact catcgaactc ctcttgtgtc aaataagtca tgtgtaacct cccttaaaaa
    10561 taaagggtgt tgccacccct tatttaatct tcaacagttg cctgagatgc atcttctaca
    10621 gatggggcat cttctggttc aagcgttcca tttttgtcaa caagttctaa aacatttttc
    10681 acatctggaa aagcattttt tagtttcttg ttgacttctt tagcataatc ttcatcaagt
    10741 tcaataatgt catcgacaat cacatccatg ttgagttgct caaagaaaag attttttgtt
    10801 gctttgtaaa gtgccatgtt ctacctccta tacaatagtt cctgtaactt tgtaaattgc
    10861 tttcttattg tcatcaagag tgtaagtacc acccttagca gcagcttgca atttcacacc
    10921 atcaaagttt tcagcctcaa ttacacgggc tgttgagata ccaacaaacg gaatgataat
    10981 accgtttggt gagaagatag cgataactcc tgtctcaaag tattgtgctg gcgtttcttc
    11041 caaggtaaag cccttatatt ttggtagccc gttttcatca agggagatag ttgccccttt
    11101 ggcgcttgta actgatgcca tatctacgat ggcgttgtaa aattcagaac gcaagtaaac
    11161 agtaatcggc gctgtaactt cgttgtttgt gtaaaaagcc gacaacttat tgaataaagc
    11221 ttttactttg tcatctgtaa aatcagcaag ggcttccgtc ttagtagcgt tgtcagacaa
    11281 gtatttacca attcgcttgt tcactgttcg agtttgtgcc tcggattgca acttcaagcg
    11341 gtcggcaaca gcagcgttaa gatcattgtt tactgtgtaa cggtcaagcc cctcatggat
    11401 tgtaagggta tagtcatagt tgacatctgt attttcatat ttaacttctg tcaaaccacc
    11461 aaagcgtgac tgagcccctg agttatcacc aaaaccacca tcattttcac cggttttgta
    11521 ctcaccgatt acaactggtg tgttgtttgt tttaactgag aaagccttag agttttcttg
    11581 taccccatcc aaaatctgaa taggtgctag agcgtttgaa aatgctgccc gcactccaaa
    11641 aactgtctca agaatgcccg catattgttt ctcatagcgg cgcactgcgt tgttttgatt
    11701 acttggcatt tgtaatctcc tttctgttat ttgccatacc cgtcaataat cgcttggaac
    11761 ggatcaacat cacttgtacc ctctcctgcc ggattacctt gaggtaaaat attggggcta
    11821 ggcttacttt cttcagcttt gaacagatat ggatcacttt cttttaaacc gttgattact
    11881 tcatcaatct gaggtttccc gttgtcgtct aactggatag catcaacatc aatgaatttc
    11941 atcaatttgt ctggattgaa agcatttgta tctttcagag ctagactgat agcactaacc
    12001 ttttttgttt gtgcaagttc agctgcagct tcgtttttat acttgtcata ttcagcttgc
    12061 aatttatcaa tcgcatcttt ttgttcagcg ctgatattct caagtgattt caagtgttca
    12121 acttgctcct ctgctttttg caactgtgat ttgagactat ctcgctcttg tttgatagtt
    12181 tctaaggctg atttgtcctc attcagctct tttcctcgca aagcaaagac tgacttagcc
    12241 tgttcttctg tcaacccaag attgagtagt tcttcagttg taaatgccat ttgtaccctc
    12301 ctagttcttt tttaggtgga taactcccac ctaaagcaaa atattattta ctctctcaat
    12361 atacctttga tggataggga ttttttacgg ttttaaacac aaaaaaggac ttgtgaaaca
    12421 caaatccttt atgaaatata taatttctct cgtctgtaat ctcttgttaa gaaatcatgc
    12481 tgatttatca agttacggat cttagtttga taccctctaa ctttcaaacg ctcagcttgt
    12541 atcatcttgt catcttgcaa ggtatgagcg taatgcaacc gctctttatg tgtcttgata
    12601 agtctctcaa ggcctctttg acctgcttca atgcgtgcat tttcttcagc ttgttctggt
    12661 gttagattct tcaggtagtc tggtaagttc ggtaactcat gaactccaac aataaacggt
    12721 gtcagataat gaccacaatg gattcctaaa catcctgctg ctgttccata cccataatcc
    12781 aataatgaat agatagttat cccgtctatc ttcctaccag ccccttttgt aactatctgc
    12841 ccttgtaacg gactacaagc tggtctagcc attgctttca tcgaatagta aaaagtatct
    12901 actcctaact cctcagcagg tctagtacgc atttcgttat aaactttgta tgttgtgctc
    12961 ttgataatag ccctcgcata gctatcagct ttccaatgcc tcccaccttt atcgacaaag
    13021 cccgtaaaag cgttcttctg ccatttcatg atggtatcat gcaaagcaac atcgcttgtt
    13081 ttagttcctg caactacctg tgcgactgtc tcctccacaa tcgatttata agctacttgc
    13141 aagctcttag gtaatgttgt attgataagg tttaaatcac taactgcttg cctcgaataa
    13201 gcctctaagc tgtccgttac gccatttgaa atctctccct caggtatttt attcaaatct
    13261 tcttcaagtt gctgtttagt gtccttatag actttcaaac cttcattctc aattacatca
    13321 cgcaacaatc tttcagcaat tcctgtacgc tctgaaataa gctttagatt ctgttcattg
    13381 agcatgtgca tatcatttag tttctctaac tgccagatat aagggtttct cattaaatca
    13441 atagacccac gctcttttaa gcgttttatc atacggtcaa agatatcaat ctgtaatttt
    13501 tcgtaaatat ccccaacgcc ttgcatttgc aaaggaaatt gttggtcgtt aaacgtgagc
    13561 tgttttctct tttttttcat tcaaaagccc tctcttgaaa gaaaattggc caattgacca
    13621 gtttattctt ctaattcgta ttctagttca gaaacatcct tgattagttt tttaataact
    13681 gaagaggcat ctagtctccc gctccctcta attattaaac ctagttttat tgttggcgta
    13741 tcttcaatgc ttgctgagta gtcaacacta gtaactccga atttaacctt tgtcatcttc
    13801 ttcctcctcg ttttggtcat acataccata aatagcaagt tcggcatcat tcataggtag
    13861 caactcacta ttgatagcat tgagttcttt ttctgcctca acaccagaaa tatttaatgt
    13921 cttaccaatt gcccgttttt tggttgagaa tcctgcggct accattttag cccaataatc
    13981 aagttctgca tgcctatcag taaatacacc atcatccaaa ttaactgaaa tatcatcaag
    14041 ttctggaatt tctccgctat aaacccctac cgccttaccg agctcacaca ttgaaacaca
    14101 aagctccttg atagattgtt caacaagtgc gacaatacta cttcgcatct gataagtgtc
    14161 tgagttctcg ctgacaattt ctgttgcggt tttcattcct tgaccatcga atgtaaacat
    14221 gccacttgat acaccaatct gcatttcaaa gagtttcaat ccctctgaaa tcgccaaaat
    14281 ataatcattt gctcgaattg gtgaggtaag gtctgtaatg cccccggcat ccatactaga
    14341 gccgccaatt tgcatataaa cattctgctc aacatcaaac cgtggtctaa aatctattgt
    14401 tccatctgga cgttgatatt gtctttgtgt tagatgttcg ggcacaataa ctcgtctttg
    14461 tcccatcctc acttcccaca taaattcatc gtaagaacga ttgatgaagt caatagtcgt
    14521 ctttgcgtta tcaaagatag acaatccaag agggctgttg atgtctttgt tattcatacc
    14581 tggagttttt agataagtaa atagaggtct tgataggttt tcaaagactg ttacaggctc
    14641 taaatttttg tacttgtcta gttcactcaa gttcacacgt tgacctaaca catcattcac
    14701 atctgaccta taaagttcat ttgtaatacg ataatacttt ttatcgtttg tgctacctgt
    14761 ttcttgtccg tctgctgtta cccattcgtg aaattcaaca agggtatagt aaacgttctt
    14821 acgcccctca gatttgatag tcttagtaag gattgcagca cttgaaacat cttgtgtgtt
    14881 gctttctagt ggaaagaaca caggcgcttg aataaatgcc actctgacct tatccccgtc
    14941 aatataaggg cgcatagcta ggccaccaag tgccaaacag ctttctaaat accgctcaaa
    15001 attcttattg aatcggtcgt tagttagcat gtcatccaaa aatttctgta aaatttcgtt
    15061 ttttgttgtg atagttgcct gttcattgta aactaagcta gcaatcttct tcgatgctgt
    15121 tcttgcaatt ggcaagtgat tcattggacg ggatttaata tctccatccg tattcttgta
    15181 ctgaacatca tcccattttg attgatagta gactagattt ctcttaatcc ggtcatactc
    15241 ctcttgagtc actgcaattt ttggatgttc caaaatacta ttaagatttg atgtctgcat
    15301 gtaatacctc cctcgactaa aaaagtcttt tactttttga aataggctca tgatcgtcct
    15361 cctctaaacg ttaccaacac gcaaaccgag caattttgca ttgtctaaca caaaatactg
    15421 tgttgtgtcg catgtatggt catcttcttt gataacgcta ggattatcag atttgatagt
    15481 cttttcatcc caacgataca tcttgtgttc ttcaataaat atcttgttgt tttcggtgtt
    15541 gagatagtaa aagcgacctt gagcaagcaa agattgaaaa ctgtcaatca tagtcacttt
    15601 tctaagttta gcgactggat gccatttcaa accaaagtca agaaacatct ggtttcttaa
    15661 cgctccctca gcactatcta ttgtgtattg caaggcttgt actctgtact tctcaataac
    15721 tgatcgcata taagcatata tctctttaga taactgacta ggcgctttct ttaccacttg
    15781 tccagctggt gaataatacc aagtatctag taatataacc ttacctttag ctgttattcc
    15841 aaaagcgcaa caagcggttg ctgactgttg atgtccgcca tctagcgcaa atgatatgcc
    15901 aatcagctta tcatcgctag gcaaagcatc aatagcatga aacatactca tgttatacac
    15961 gttgttacct aatcccactg cctcacctag atataagtat ctgtaataat cgtagtcatt
    16021 ctctttgata cgctctatat cttctagcat ctgctcagta acgaatccga gttcatcatc
    16081 aagataggtg cttgagtgag ctaaatagtt cttattcgtt ttgatgctct caaaccattc
    16141 attgatccaa ctatatggat ttctaggtgg attgtaactc caaaagaatt gtacaaactt
    16201 ggcgcgtggg tgtttctgcc tcatgaacgt cacgtttgat tggtcaaagt cctcttggtc
    16261 attaaattca gcagcctctt cataccaaac cgctatgata tttccaatgt cgtttgattt
    16321 gagtttttga aagtcatctt gtccgtaaaa gtaaaatgtt gagccggtcg ttttgtgtac
    16381 gattttaaac gggctaactg tttttgtgaa ctgctcagct ataccaaaaa ggttcaatgc
    16441 ccaccaaact ttattgaaaa cactgtctct aatagtattg gccaccttac ggataacaac
    16501 gatattggcc gcctctccag cgataatata ccttatcatc atatacgcta gtttaagtac
    16561 aataaccgat gatttaaaag agttacgccc acctttcaaa acattataag gtaagctaga
    16621 aatccaaaca gatttgaaat gagggttgat gttcttctgg acattaaagg tcatccgttg
    16681 cccccctcac atcttcagcc catgcatcca ctatctcgat agtttcactt gagcctttct
    16741 cagcttcagc acgctctcta ttttcatatt tgagtgcttt aatacgctct ttctgttctt
    16801 gtatatcgta tttatcttta gtatttgtca gcttgattat gttctcagtc gctttctgat
    16861 tgccttttac agcttgctga aaggttgcaa aggctagcaa agcctcgtta ttgccagcca
    16921 tacccatctc ctcaagttgt ttcttgattt tactatccgt cacatccaaa gataagagga
    16981 tttcaaatgc tttttttaga tcagcttttt ttcttcttgc tatgccagat gctttacctc
    17041 cttttgagct aatagctctt gcttcatctt tggttcgttc tgtaactggt tttaaatttt
    17101 tagttccatc tctaggcaat ttccaccctc ctttcaaaca aaaaaatcac aagcatttta
    17161 tacttatgat ttcattgtat atgttaaaaa aggggatgtt ttacgctatt cctaataact
    17221 tttcgatttt gttaatcaag tctctatatt ttgagttgtc attttcgttg ttgacaagtt
    17281 taattttgct cctctaccac ccatacctta gcctcttttc ttttactcgt atgagtaagt
    17341 gtacccgtat ttcttagcgt ttttcttgag ccataggtca gctcctttat tgtaatcttt
    17401 tgtagtaaaa cgtgacttgc tcacagcttt atcaaagcct ttagcatcaa agttagcccc
    17461 ttttgtaatt cgatacgctt tagagctatt cgttgcaact agtgtattca taccttttaa
    17521 tgctgcaaag ctatgtaaat ctgtacttga gaaattgctg ccattcggat ggttatgtat
    17581 tgctgtaaat ccaccagaga taggcaaaat ttgtacgctg tttttcccac cgtgtacata
    17641 attatgagca aagccttgag agtcaactgc tgtactgtat tctgttctag agccaccgtg
    17701 ttttttaata aattcctgga tagttccctc aacacttgaa aagcgccctt gattgtttaa
    17761 agatgctgga tgtaaggctt ttgagctccc actatctctt gcaccaccag cacctctaaa
    17821 acccggatac ttaccgtctt tccctttctc aaaatttgca ccacgtccac cgcctagagt
    17881 gaaattgatt ttatttactt tttccatcaa agataggtca ttttctgcct cctcgataga
    17941 ttggtattgt ttgcttgttt ctgtttcttt attgtaaagc tcaagatctt caaataaaat
    18001 ctctttacct agatcaatac ttgaaacatg tttaaaaata tcttttagtt tagttagttt
    18061 ttgtgccact ttctttcatc ctttccgttg ttgcattttc aaaatataca acctctatat
    18121 ctttataatc gtattccact tttccgccat atactacaat tctttttgga gtcaaccgtt
    18181 ttatcatctc agtaactcca tttttccata cctcaaactg ctctttgttt tgctttacgc
    18241 ctattgtact gattgctagc gttgagtttt taggcaagcc gtcaaaacaa aaatcaaagc
    18301 tttcctcact agcccacgat acagtaggga taactgtaag gccgtaatct tgcataatct
    18361 gacctatcag ccttgacctg taaatgttcc atacttgcat agcgataggc atatcaagat
    18421 ataagctaaa atccggagct aaggcgctat caaattctag cagcttttca atgtaaaagt
    18481 ctggtctttg ccatattctt tcaaattgat aatcatctag gaaaaaatgc acgcatgagc
    18541 tgtaatctgg tttatttaaa acataattaa agccttgaaa atctttagga atatgatcca
    18601 cgccctcgat tttaggcatg ttataaaaac cctcaaccct tgtatcgtca taatgaaaaa
    18661 gattgtactg atttatagtt gtgtctctgt gaaaatcctc agcatcttcc tcctcgtttt
    18721 cagtttcctc ttgctgctcc tcctcgttac caaagttgaa ccctgtaact gataactcaa
    18781 aaccaaactg agccatatct attgtttcaa attgagaaag ctcaatattt aataattctg
    18841 agtcccacgt tgaatactca gcaactcgat tatctgctag tctataagct tttatctgct
    18901 catctgtgag gtttacagcg tgagcgatag gtattgtgtc tatacctaaa gaaagagcag
    18961 cctttagcct agtatgtcct gtaataatga tgttattatc atctactaag ataggttgct
    19021 gaaaaccaaa agcttttatg gatgcagcaa ctttctctgt tgcctctccg tcattatgcc
    19081 tagcgttttt gtgatatggt ttaatggatt ttatatctac atattcaatc tgtaacatct
    19141 ccatatctct cctttcgaaa aagcttatat atcttgatta tagatacata agctttggat
    19201 tttttacggt tatttatcta agatggcgtt ttctagtaat tctgtgtaag tcgcacgaaa
    19261 ataatcgtta aaccacgcat taagtaatac ataggcttga gtcggactat aaaatagtat
    19321 tttttgacaa gctccaatga cattcatgtt ttcgtaaaca taaacctctt ttattgcccg
    19381 caaatattta ggatcagact tatctataaa atcttcagtt gattttttta agttgcttaa
    19441 aaacttagct tcaagcctat cagttttgat atgagaaact ataatctttt gctccaaaat
    19501 ggttctcttt ggatttttct tatccctcaa aaaataccac tttagccaat tgatttccct
    19561 gcgatggata actgacaagc gctctatttt tttcttcgtc atcagtcatg tatcacctcc
    19621 tcaaaataac tatgaaattt acttaaattg acaatagcaa cctcttcaac agaatgcttt
    19681 ccgatgtcaa agtctggatc attcttccca aactcttttt ctatagcttt ttcagccaga
    19741 aaaggcaaat cgaatatact tgccccattt cttaaagcga gcgcttgacc gtgtttgttt
    19801 actattcgat aacccacatc ggacggtctg atttccttag gtatttttat gcgttcgctt
    19861 tcagcttttg cagcttgttc aagtgtttgt gtcattactt cacctcatta actttctaac
    19921 gcacaaattc gttgaccaga tcgctgataa ggaacttcca atcagattct ctaaaggtca
    19981 aaaaatgatc tgcggtcaaa tttctaatcc ttttataaaa gagtatcttt agttggattg
    20041 attcaccaac agtaaggaag ataccaggaa atcgatgtac agaatgcact ctatttccgt
    20101 atccagaaat atctaaatgt attaacattt ctggatatga acgtccaatc ttagcttcaa
    20161 ctccgagctc aactttgacc tcttccataa ttggaacctc gttaaaaatt ggtcgtgcag
    20221 aaaataatgg cgacgatgtt tcttgttttt ttcttcttcc caaaaatgga tatttacaag
    20281 gtctcatttg ccgtcctccc caataatatc caatactttc aaaagtttat ctactgaatt
    20341 ttgagtgata gaaatatgat gttctcctaa attgtaaggt gttcttaaaa acaagatatt
    20401 agggcctaga cagaggcgac taatatcatc tatgttgata agctcatcat cagtatgtcc
    20461 tctataacaa gattgtattt taacaaattt tgtcatttat tccacctcct caatctcaat
    20521 acctgggcaa tcaaacaccc agccgaagtt tgcgtcttct agttctttac gagtgtggga
    20581 atatataaca ttgtctaaac taaagttttt tgtaaagaaa taccttttca aaagttctcc
    20641 ataaaccaac atatttcctt taatattccc tttaatctta acaaaatacc gcttctcttt
    20701 ttcgacctcg tagccgttaa gccaagcaag acagaatttt tcgatgttat tttcgtaaaa
    20761 ccaatcagga actttcttat cataatgatc ttcaattact ctcattgcac cgtaaacatg
    20821 aaaattgttt ttctttttaa attctatata ttccgccaca cactgcggta ctacgacttt
    20881 aattttggat ttatcaacga tgtcgtctgt aatataaata ttattgttgg gtacattgag
    20941 agtttgcccg tattccaatc taacaacatt ttcaacgcac ttgttctcat ccacatcaaa
    21001 accgactatt ttccctttca agagaacttc atcccctata aaaaagttaa agcgtggtgt
    21061 ttcaattaga tctttattca ttttccacct cctctatatc aaactctaat ctataatgcc
    21121 ctttttcctc acttaagcca ccataaacaa aggataactt tttgataacc ttatgattat
    21181 catctgtcca aatacctgca tcagtcatgc catcaatgat agccttgact gtcggataca
    21241 agttaggtgg atctaattta gacttagtag ggctgtaaat tgtaactgta acctcacaag
    21301 ggttagaggg gctaaaagca gccctccctt tatccttgtt cattgatgta tgccaataag
    21361 caaaagctct aatgcgctta gtaactttag ccttatctgt ttgatgttgt ctgtcattac
    21421 tattgataac catgtttaga gattttagct tagtattccg aggcaaagaa aactcaaatt
    21481 tcattttgat taccttaaaa ctcaatgttt tcaatttctg cacgctgttc aaggatcttg
    21541 agatatgcac acattgtata gtgttgagtt tcaagtaact caataggaca ttttagttta
    21601 aaatcaagtg ttcctacgta atagttacta atcatcaaac ttaacttatt ggtgcgctct
    21661 tttaattgtt tgtattcttc aatcatccgt tgtttgtaat cactcatttt aatttccact
    21721 ttcttatgct aatactgtga tatgtttttg gtctgctagt tgctctttta gataggctgc
    21781 aatgtttcct actgcatcag ctacccaacg cttaccatct gcctcaaata aagccatatt
    21841 ggcttgctta tcaatcctaa agacaaatag gcttgccggt tgctcaacct cgctaaatgt
    21901 acgatatggg cgcaatgtaa ccggattagg tgctttgcct ttagcaaggc ttgccacccc
    21961 tgttttaact gttgctactt gagatactcc attatcttca atttcagccc cattctcaat
    22021 tttcaatgcg ctagcaaatt ctagcaatgt gccacgatcg ttatcgtcaa taaagtttga
    22081 ttgcaacatg atattgaact gttccgatga taggaaacgg ccaaaagata actctgggat
    22141 gcgtgcctta acatcaacaa gtaatgtgcg acgttctaac tcatcatttt cagaccacac
    22201 acaaacctca tcatttttct caactgctac aatcaagcgt tggtttttca aattgtttag
    22261 gtctgttttg agatagtcaa caaggcttgt caaggttgat agctccagag ttttaggata
    22321 gcgtttaggg tcaagttctt tgaggttgaa tttgttggca tcataatact ctgttccatc
    22381 tgcagctgtt aaaatttcca aaccatgctc atttagttct actgcgtatt ccaatgctga
    22441 tttaagattt tctgttgtca tattagttac ctactttctt tttgttgaaa tcaataatat
    22501 ctgattttgt ttctgcttgt tgttcaattt ctgccactgg ttgcccaata tccgtcagaa
    22561 tttctccgtt ttcatcaaaa tacatttgac caggtactgt acttttcagc tcgttagcat
    22621 gtacttgtcc tgtatcaaaa tcacgcccaa taagaattgt tgtagctact ccattttgag
    22681 gcgcaaattt tgatttcacc tccatggcag tatcaacaac tgtacgctct tcatttgctg
    22741 acattgtaag tgtgatagtc acttttcgtt ttgctttcgc atctgtattt aggtcaagga
    22801 tgttatcaaa gactttttca agctctttgt ctagtttctc ctgtaatcct ccatctgcaa
    22861 tgtgggttag atctaaccca ataagttttt tatccatatt gtcctcctgc tttaaattaa
    22921 gctaatttga aatagcgcca tcaaatactt tcatctaaac acctccccac catctgagta
    22981 ccatttgttt ttaagtacat gacgtgcaat ctcacattgc acttgtggtt tctgataata
    23041 atccactttt gccttgtgct ttttgatagc ttgcatagtg tgaattgtaa caatcgctgc
    23101 ccatgtgata gacatcaaag ttgtaagtac cataacgatt tcaatttttg tcattttctg
    23161 tttccttttc aaattggttt aaatagggtt aatttcctcc taacccctgt gctattgcag
    23221 aaataacgtt tactgttacg ctattgcctg cttgcttgta taattgactg ttagagttga
    23281 cctcctgcgc cttatcaaaa gcccaatcag gaaaaccttg taacctccag cattctctag
    23341 gtgtcagctt tctaatccta aaatcaggct caaccacacc ttgactctct ccagttaaga
    23401 gagtatttgc tatctgctta cctactcgcc ctctgcgtgt tttagagttt ggatgcgata
    23461 ggtttacact atctccaatt tcagcctctt ggtagccttg cttggttgct tcttttactc
    23521 tgattttagg ctcaagtcct ccaccttgat aggctctgat agttggtgcg ataccgtctg
    23581 tttcgtaaac caccccacat tggttaaaat tgggttgcaa taccccaaat tgttttatag
    23641 tattgctttt tatagctatc ttttgcccct ctcccttgtt tgttgttagc gtgggagcta
    23701 gaccatcagc ttgatagact tccccattca ttccgttgcc agatgggttt atattcccaa
    23761 ttttcatgac tgattggtta ctagttgact gattttttcc gctgagagga aaaattcttc
    23821 tggtatgttc tcttctaaga tgtccgataa tgaacactcg ttcccgattt tgggggactc
    23881 cgaaattctt gctgttaagc acttgccatt ccacatcata ccccagttca tccaacgctg
    23941 agaggatgac ctcaaaggta tttcctctgt cgtggttgag gagtcccttg acgttttcaa
    24001 ggaatagata tctgggtttg agaatagatg cgaaccttgc gatttcaaag aagagagttc
    24061 ctcttgtatc ttcaaatcct cgtctgtttc ctgcaatgct gaaagcctgg cacggaaatc
    24121 ctccacagat aacatcaaca tgtccgattc ctcgaatagt gtcatctgat actgttgtga
    24181 tgtcatgtaa ttcaatttct cctttcgtat cgtgtatagc tttataacta gctctagcga
    24241 atttgtctat ttcacaaaat cctatacatt catgcccggc tgattccatg ccgatcctaa
    24301 aacctccaat gccagcaaat aagtctaaga atttcatttt ctgcactata tcaccccctc
    24361 atcttatttc tgatggtgaa agagtgttta ggtggtgcat cctcaaaagc atcttgaaac
    24421 tcttgattga ttttgcgaat attaaacggc tcgacggcat ggaaataata accatgttca
    24481 tcagtttccc cctcgatacc agttgcccac gacaagaaaa cagcttgttt acacgatggg
    24541 caagtaatag ccttgcgatg cgctcctacc ttaaccacct tacagtttcc acaaaatggg
    24601 cattgtaagt cgactttaac tttgataaat tccattcagc acctctttct aaaacggtaa
    24661 atcatcatca ctaatatcca atggatttgt gggtctgcca aatggattgt tatcacgggt
    24721 gaaatcagga actagatttg ttgtgttccc ctcaaagaaa ctgccttgtt gcccgtaact
    24781 atttccattt tggaaattgt tcccttggtt atttccattt tggaaagaac tgccttgatt
    24841 actgtagccc tgctgctgat aaccgccatg atggtcttga tgaccttgat tattttgctg
    24901 actgttacga ctttccaaca gttgaaaatt actggcaaca acttctgtga cataaacacg
    24961 ttgaccttgc tggttatcat agctacgtgt ttgaattact cctgtaactc cgataagaga
    25021 acctttttta gcccaattaa caagattttc agctgactgt ctccagataa cgcaattgat
    25081 aaaatcagcc tcacgctctc cagcctcgtt cttaaatgga cggtttacag caagagtaaa
    25141 cgtagcaacc gcaatattag attgcgtgta tctcagttcg gcatctcttg taagtcgccc
    25201 tactaaaaca acgttattta tcattttgca cctcctctac ttctgatacc ttgatttcat
    25261 ttgaaccaaa ctttaataag ccggtatatc gtttcacaaa ctcaatagcg gccataaatg
    25321 aattttctgc attgatttct gaccccaaat caagatctgc aattttaccg ctgacataaa
    25381 aacatctcat aggtctgact ccttattcta cttaatcctc caaagtttca aaaccgataa
    25441 agttatcctc aaaatattct tgtgtatttt cccactgttc taaaccaccg tgcaattcaa
    25501 gacgtactaa tttgaccaaa ggctcgctag gctcaaattt tgccacctct cgcgcattgt
    25561 tttgaggttc tggtgtaatt gtaccctgtt ccaaaatctc gcctgtttcg gcatcgtaag
    25621 ccttgatatt cgcattagca tttttcttgg ccgattgagc aatttcttca agtcgttcag
    25681 cttttgcttt ttcttgagcc tctttctgct ctttgcgtgc aatctcagca tctcggtcag
    25741 ttttcatcat cttgagtata tcaacaagac tcttaccatc ttcaagatgt ctgatatagc
    25801 tatcagctgg caaatcgtac tcttgagctt gctcttggat agcttgcttg ttagccttgt
    25861 attcttccag ggcatcaaat tctgaaagta ctaagccatc catttcatca agtgttgtct
    25921 ttttcagctc atacttgcct gttttaaaat atttcttgag gctgtactca tcgtatttgt
    25981 cagcgaatgt ggatttttca atccctgcga ccatacactt atcctcaaat gtagcacgca
    26041 cgacatccac gcgcatcaat cgttcatgtt catcaatcgc attaagtcct gctgacatag
    26101 catctgttac gccctcaata ggcttgatga ctttttcttt gacccactta tcaaagtctt
    26161 ttgccggctc attgatttgt cggttaaaat ctttgcgttg agtgtctaag cccccaatca
    26221 gcttattaaa gcgggttcgc tcttcataaa cttctttgta attatcaata gtaacctcgc
    26281 gaccgctata ctgtgcaatg gctgcggcta cttgtgcctc gatcgcctca cggtcaacat
    26341 taattactgc aggttgaaaa tccaccttga tttctgtcaa gctattagtt acatctttta
    26401 ccatgtttaa ttacctctct ttgcttttgc ttttgctagt tgttcagtta aatagttttt
    26461 caatacctcg tagtcaccaa cttgtactct atgaaaatct tgtaaacctt ttaatttttc
    26521 agatagtaca tagttagcaa gcgtatcgaa cggcatccct ttaatttttg caatatcatt
    26581 tataaggtcg ttaatttctt gatattgagt gttgtcaata taccttactt gattttgtcc
    26641 ttgggcttgc tgattgtttg gtttctgttg ctgattattc tgtccttgct cttggctttc
    26701 ttctactgga tactcatcaa catcctcacc tccaatggca aataaacctt gtaaagcata
    26761 ttttctagca taagaaccaa ccgcacctgt ccattgtgga tcttgcatct gtttcacatc
    26821 ccctttttgt gtgtgaaaaa ttggtacatc ttcttctcta gcccatccaa tagctttttc
    26881 aatcgtgcca tcactttctc ttttagcaac agctaccgct ttataataca gtttgtcacc
    26941 tttttgaatg atgtcatctt ctggaaatga tacactccaa ccgctatcca aagacttaaa
    27001 tttattattt atgtcctctg cggttctaaa cggatatttc actccctgtt tcgtttgttt
    27061 ttcgatttgc atttttcgct gtaattctgc aaatgttaaa tcagccatat tatctatcct
    27121 ccaagtctac taaaaggcac atcccatgaa tagttagtaa agttttcgtt tacaatattc
    27181 ttgatgattt caccttttga aatttcaatt tcctgtgtaa attccatacc catttcaaaa
    27241 gtgaaaattt taatatcaac atcaaactta ctagaaattt ctgtgtaatt gtcagctaat
    27301 gctgcccatg cttgtttgaa atcttcaagt tcgataatca caaaatcatc atccaaccaa
    27361 atttcaatat ctttactaga aataaacgca cgtcttgtac cgtttatata aaaataatca
    27421 tactcgtttt taaatcttag tagagtgcca tcgtattctt cttcaagcgt tgcgccttta
    27481 tttcctaata gcatttcttt taaagctgat gcaacgtttt cgcgtctgcc tcttaattta
    27541 agagtcccct ctgcccaatt tggcatattt ctttcctcct ttaaaaactc tataaatccc
    27601 ttatttctat aaggatgagt ttgttatttg ttagtagtta ttattctgct atcgtgtcat
    27661 cttaacggtt ttagccattt ctttcttcca tggttgactg cctcgatatt gcagataagc
    27721 atcaaaacct ttgattgtga caagctgacc atcatttcta aggtattttt gctgactagg
    27781 caattttttc atctctcgcc tcatatctcc cgcttgccgt tttgaacatc caaagatgcg
    27841 ctctagttct tcatcgtttg cagaaatctt ctcgatgatc acatctttaa ttctcacgat
    27901 ttgaactgtt tccatttttc ccctttcatg ctataattaa gttagatttt tttagaaagt
    27961 gtctgagttt ctcagatact tttttgtata ctctctttta tttattaaga gtagtacttg
    28021 ttgttagtta gtatttattg ttatttaata cttgttgtta attagtattt attagtgccc
    28081 aaaatctgac atctcacttt ctgacatctc actttctgac atctcacttt ttggaatgtc
    28141 agaattataa ttcatagacg cccttttgat agataggttc aatctctgtt tcataatatc
    28201 gaattggaaa tcagatattt ttacatctga aaagaatctg aatatatgac tccctccatt
    28261 tccaggaggt ttttttctga tttttcgtaa atatccagcc tcttcaaaga ttttgaaata
    28321 cttatcgatt gtctttcggt taacaccttt tcttttagct atctcatccg gatagacttg
    28381 ccaatttggg tgattagcca gcaccaccat catgatgcca accgctgtaa aatccagcgc
    28441 aggatcgttg ataaaactat tactaacagc agtataattt tcagtcgcat tcttgaaaga
    28501 taaattgaca atctaaattt ttaaagtctg tcatacagtc tcctttctct tcacttattt
    28561 tcaatcattc tttctacttt ctaacctgtc aggtattcct aattaaggaa cttatcgata
    28621 aaatactgtt gtcctttgcc tgtgaccttt ggtgtcttgt tcacagtgat atgtccatct
    28681 gcgtgttgca cgtttgtttc cttgatttca aagagtttca agtccatgct acgttgggtt
    28741 ggcatgttcc aatctgagcc tttgcgctta atcaggtagc cattttcgcg catccaagaa
    28801 aagaggcgat tggcaccgat tttgtagccg ttttggctaa tgagcttggc aagttcgcca
    28861 accaagatag atgtatggct tgcacttact gcgtctgcaa agaggacttt gggtttgtcc
    28921 gcttcaatct gagcctccag cttgtggact ttctgatcag ccatgagcaa tgctcttgcc
    28981 ataatcttct cagggctatt aaagtctttt tctacttgga taaagtattg tcggacttct
    29041 tttcctttgt ccgttcgttg aatcatggcg atttctttag ccatgtctag tttgatgatg
    29101 tggtcagtca tatcttgcag acctccaggg gtcggacatt tttgggtcac ccttgcgaaa
    29161 tcctgatttt cttcaaaacc atactccgcc attcttccaa accattttct atattctgtt
    29221 ttaactccca atgcctcatg caactgacga ccagatacaa tcggttcatg attgtcattc
    29281 acagtcactt taataacttc attcatgtta ttccctccta ctcctcaaat cgttcccatg
    29341 actcgttgat tcgcaatttt ttattaatgc gaagcttcaa gtcatcactt cctttaccat
    29401 ctttcagcaa ctgcgtaata gctgatggac taacacctac gacggtagct aggtccgtct
    29461 gcgaccaccc acgtttttca attcgctctt ttacaagctc aatccattta agatgttgtt
    29521 ggctcatgcg acctcctcct ttttgaaaat aaaaaatgcc ctatctaact gatagagcat
    29581 gtggtataat agtgacggca cttctacacc gcctacgaaa ggaggtgaga tagcccatga
    29641 tggaactaat ccttaaaact atcatcggac cgattgtggt cggtgtcgtt cttcgtttag
    29701 ctgataaatg gctgaacaag gacaaatagt gtcaaaaaaa gaccccaagc ttaatgtgga
    29761 agttagcctg gggtcttttc tagtccatga tatagaacta atccttaatt cccctttatt
    29821 atctcacatg ctctattcaa ttgtcaagga acaaagttaa agagttagta aattatttta
    29881 taaaatgctt gacatatctc acccaaaagg ttaaaatgaa agcataatta aaaaccttga
    29941 taaaacctta tatctatcaa cttatttgct cgccaaagct atttattttt agataagttt
    30001 taacttagtt ttttactaac tcattaactt acaaaaacta ttttacaccc agttaggtga
    30061 tatgtcaaca cttttcaccc aaaaagttga aatatttttt gtcatgttcc agaaaggttg
    30121 atttaacaat gtttccgaca tacgaaaaaa tcaaagaact tgctgataag catgggattt
    30181 ctcttatgaa gttagaagaa gatttgggtt acagtagaaa tacactctat aagttgaaat
    30241 cacaaaagcc caatgctgaa cgaatttcag aaatcgccga ctacttcaat gtctctacag
    30301 attatttact tggtcgcaca gataatccta ccatcgctaa taaaaaagaa caattctttt
    30361 tcgaaggcaa agaagtcgat gttgaggaac ttgcctctac tgctatgcgc ttcaatggta
    30421 aaccactaac tgaagaagat aaaaaagcaa ttcaaaacat aatagagatc tatctcagaa
    30481 aacaataata atcaaaggtt ggattgttta tgactgaaaa agaattttct caaaatctag
    30541 gcatagatat agagattttt gaagatggtc tatttccaga tgaagccttt tacatcccag
    30601 ccctcaaaac tatgtttttg agtgatgcta tatctgatga aaaaagggta caagtcgctt
    30661 tacatgagat aggccataga aaccacgcgc cagatactta tcagcttttt cgggaaaagt
    30721 gtgagcttga ggctaatagg aatatgatcc atcaccttat gaaagctgag ttggatatag
    30781 ccgaagatgc cactacattt aattacctgg tatttatgga aaagtataat ttaaaaacca
    30841 ttgccgatga aatcatggtc aaagaagaat atttagcact acttaattaa aaaaggagag
    30901 aaaatgaata taattgctat tatcataatt gttatttttg ttggaggtgt cataggtgca
    30961 gtaattgata accaaaaaaa atctccagag cagagagaac gtgaacttga aacatttaga
    31021 gcaaatcaag agaagaaaaa gcaagagaaa aagcagaata tcatcacttg ccctaattgt
    31081 aagtctaaag atgtgacttt cttacaacaa gacaaaaaag ccttttctgt tggaaaggcc
    31141 gttggtggag ctgttttgac tggtggagtt ggtgctttag ctggatttgc tggcaaaaaa
    31201 ggaaataaac agtggcattg ccaaaattgc ggaaatttct ttgaaacgaa ataaaaaaat
    31261 ccccacactc gtcatcgcca aatcttgagt gtgaggaaat catgtatagg aaacaaccat
    31321 tcaaaaggtc gttttcttat acccatttta tcaaaaaagt gaggtaaaat caatgtggat
    31381 ggaagaactt tccaacggaa aatacaaatt ttttgagcga tataaagatc catatactga
    31441 gaaattaaaa aaagtttcag taaccatgga gaagaaaact ccacaagcaa gaaatcaagc
    31501 cgccatcttg ttgcaggaaa agataaaaca aaagttaggg gaaaaacaac attctgtttc
    31561 taatataact tttgaaaaac tatatgagga atttgaggaa aattggaaac atggtgttaa
    31621 aaattcaaca gtctatgctt caaaaaatgt aaaaaaagag attttaaagc agatagaggg
    31681 cgactaccta gttagaaata ttgatagacg tttattacaa aaagtaatag atcaactatt
    31741 acaagatggg agatctcata actatgtttc taaaatcaag ttcaagctca atcagataat
    31801 gaaattcgct atcagaatga attatattga tacaaatgaa atgctatttg ttgaaacgcc
    31861 tagaaaagta attacatccg acgaactcag aaagaaaaat acaaaatact tagaccaaaa
    31921 agagtttaag ttattcatcc aaaatttaaa agacgaggcc ctatgtgatt atcgaattac
    31981 aaagtatatc cgaatagcta aagttctttt tcttactggc atgaggtatg gagagctggc
    32041 agccttaaac tacaaggaag atatagattt ttctaaaaag actattcaca tcaagcatac
    32101 atacgatttc agacaaaaag agagaactac accaaagaca atcaagtccg atagggttat
    32161 aacagcacct caaaaagtgt tagatattat caaagagcaa ataatagaga atgcgacaaa
    32221 tggatttgat acagatttta ttttcatcaa tactctagga gaaccaataa caaatgccag
    32281 ggttatttgt gcattgaaaa gacatggtca aaaaatcggc atagaaaaaa acataactac
    32341 acatacattt agacattctc acatatccct acttgctgag ctgggcattc ccttgactgc
    32401 catcatggac agagtagggc atagtgactc aaagaccaca ctagagattt attctcacgt
    32461 tactcaaaaa atggtatcag acatatctag caagttagac aagataaaat tttaaattgt
    32521 gcccctcgtc tgcccctttt tcttatacaa gataaacaaa aaccccttaa agtgttgatt
    32581 ttaaagggtt tttaaagtgc acgaaaaaag agcacacatc ttttcctaat agaacatccc
    32641 cagtagagaa atagccgcct tttcctagtt tgctatctcc agagcccact tctttcctaa
    32701 tcttatcaga tagtttttta ccagtcagta cattcgttcg cacaatccct ttgtctaccc
    32761 ctacaaagtg ggagaacttt ttgaactctt cagaaccaga tctagcccaa ccattattaa
    32821 gggcatttgc ttttgtattt gtattctctc tcaaaagttt ggcgattaga attatattca
    32881 tcggcactta gagttgctgc tatatctgac tcttgaatac caacttcctt actaccattt
    32941 ctagcggcag tatatgtgta tttatctgtt tctacttcta gctgattatc cttaacatga
    33001 taggtaattt tctcctggta taagagtctt cagtagttta tatgctctgt catcatcttt
    33061 agctttagaa gcagctgagt ttagccaagt tggggtatta ggagtatctt tatcagcctg
    33121 tttcaagaca ttattcaagt catttgctag cctattggtt gtcctcactg tgaaagtttt
    33181 cttccagtct gaaccacttt tattagactt agatatgctc atgaaatcct ggtcaacatt
    33241 caacacaata tcgccttgtt ttttagcatc ttccgttgct tctgcttcaa attgatcatg
    33301 gagtttttgt tgctctggtg tatagttttt ttatttacac gatttaatgt actatttttt
    33361 attttagtat taagaactcc attaatacga tttttaaact ctgcttcaaa aaatccctta
    33421 atttgttggt gcgcaagttc aacattcaaa cctttcttat acaagtcttc attctgaacg
    33481 atttcggcta cacggtgaat ggtttgatcg tataccgtct tctcttaacc agcagtatcc
    33541 ttagttttaa tgactactcg ataggttcct ttagaaccgt tatagtcatc tagttttaaa
    33601 aaagcattcc aaacattcaa aaatagttga aacttccctt aatacatccg tcactttctt
    33661 tttcaagata gcccaagctt gctcaatagg attcaaatct ggtgaataag gtggtagagg
    33721 taagaaaaag tgtttatctt ggatgcagag ttcatccaaa atgttcttgg gatgaaaact
    33781 agcattgccc atgacaataa catgaggtgt cttcaaagca ggtaggagtt gcgttttgaa
    33841 ccactccaca aagaaatcgc ttgtcatgct tttcttgtaa atcatgggag ctataaactc
    33901 tccgtctact tgtcctgcaa caattgaagt tcgctcaaaa cgacgtccgc taatcttttc
    33961 atagactttc tcccctctag gagcccgtgc ataaggacga tagagatagc ggtcgattcc
    34021 tgtttcatca atataaacag gtgctaggtg ctttaaacta ttaaaattct taagaaataa
    34081 ggctactttt ctgggtcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat
    34141 ctgctttaaa gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg
    34201 taaaaaagca tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg
    34261 ctttttgacg actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac
    34321 gtgaagagag ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc
    34381 tcctttgatg gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt
    34441 agaccatgct tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact
    34501 ttttttactg aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct
    34561 gacctggttt gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat
    34621 ataatcaaat tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa
    34681 attaccagaa atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa
    34741 atatggacga aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag
    34801 gtatgcgtgg cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag
    34861 ctactgaagg attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg
    34921 tagcaattgc ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag
    34981 ttcttgctaa acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac
    35041 tatcatttgc agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca
    35101 accctgctcc atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac
    35161 acgatgcgga cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag
    35221 ttgctgatgt ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg
    35281 acgtagaata ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat
    35341 ttggtaaaga catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc
    35401 gtcgtgctct tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg
    35461 ctgacccaga cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc
    35521 ttgctgaaga acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg
    35581 ctgaccgtgt tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta
    35641 accaaatcgg tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc
    35701 ttcctgaaaa tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg
    35761 ctgaaagcta cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa
    35821 aaatccaaga attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct
    35881 tcggttactt gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg
    35941 ttgctgaact tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag
    36001 aaatctataa agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg
    36061 tcgatggtgc tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaacag
    36121 aatggaacgc aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg
    36181 ctgacggtac tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg
    36241 ctgacggttc atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca
    36301 ttgcagttgt aggggaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag
    36361 aaatcaatgc atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt
    36421 tttcgtatca aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa
    36481 gcgaggtaat ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt
    36541 tgtgcgtgcg caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa
    36601 aacttgccct tactgccgta aattttcagg tacattgtca ggtgtcgtag ctgaaaccaa
    36661 agctcacatt tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt
    36721 ccgctcacgc tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat
    36781 caacgtccgt tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta
    36841 aaaaatcagc taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt
    36901 gatattatgc gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt
    36961 taattttgga agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca
    37021 tattcaatta tccagattca atcgctatta tcgttttcct agattacaaa aaaaactacg
    37081 ttttgctaat caaaacgtag tctcagccac tattttatct tactgtcctt cttttacttc
    37141 tttggttgct acatcttctc caaaccattt ttggctgatt tcttggaact tgccgtcctt
    37201 gtaaagacta gaaaaagctt catttatctt cttaaccaag gttgtatctt ccttacgggc
    37261 tccaaccgca aaagcttctg tttctagtcc aactgtaaag acattataat cgtttaaaac
    37321 accttctgct tctaaataat agtttgcata gacacggtca atcaatagac catcaattcg
    37381 atcgtttttc aaatcaatca aggcttcatt aaaggtttgg tattgattcg cttccttatt
    37441 agcgacaata ttcttcaaaa gttctggatt tgcttcaaag tccgcataac cagatgaacc
    37501 agcttgagct cctaatgtct ttccagtcat atcctttgca gtcgtgatac cagatgattt
    37561 cttcgtaacc aatacctgct cattcttcat atatgagtta ctgaaagcca ccttttcacg
    37621 gcgttcgtct gtagcggaat agccattcca aatcagatca atcgttcctt ttgtcaattc
    37681 agcttctttc aaatcccaat caatcggttg ccaatttacc gtgattccgt atttttcaaa
    37741 aacagctgta gctaaatcaa tatcaaatcc tgcataagaa ccatctttct gagcaaatcc
    37801 cattggaaca aaagtactat caaatccaat agtaatagac ttgttagact ggtactttga
    37861 ccaattatct ccactagttt cgctagaatt tttcccacaa gctactaaga acaaagcagt
    37921 catcagactg actaatacaa gcatccattt tttcatccat ttttcctcct atttaggttc
    37981 tactttcaat aatacatctg cgatattttc agcaaactgc aaatcatggg taaccacaat
    38041 ctgggtcatc ccaagttccc tattttgcaa gattagcttc tccacttcca aacgtaattc
    38101 tggatccagg gcagaagttg gttcatcgta gccaatgatt tctgggtcaa tcatcatagc
    38161 acgcgccaaa gccactcgct gcttttgccc accagatagt gagaaaggat aggcctctgc
    38221 gtgtcctcct agtcctaact gttccaagag tccactcgcc ttcttctcag cctcttcctg
    38281 cttcattccc atggtcttca caggcgataa agtcaaattt tccagaactg atagatgagg
    38341 aaatagttga aaatcttgga agacaaatcc cagtaggttg cgcttctgca attcatccag
    38401 ctctaaaggt tgtccattat aaaagatttg ccctgaatca atggtttcaa gacctgcaag
    38461 catacgtaaa agagttgtct tacctccacc agaaggtcca acgatagcca ggatttgctt
    38521 ttcaggaata cttagactga aattagacag gatttgtttg tctccaaaga ctttattgat
    38581 atttcgtaat tctaacatgg cagcctccta tctataataa ctatacttct tctcaacttt
    38641 tttggaaata attgtcacaa tcccaatcaa aatcaaataa atggctcctg ccaagaacat
    38701 aggaactaga ctagcatcgc ggttagcagc tgttcgacta gccaagataa ggtctgaaat
    38761 tccgagagca tagaccaaag aagtatcctt gaccaaactc ataacttcat taaagacact
    38821 aggaagaaca atcttggtca cttggggcaa gataatatag cgcactctgt caaaagggct
    38881 aaactttaag accttggcag cctcatactg tcctcttgga atagtgtcaa ttcccccacg
    38941 gaaaatttct gcaaagtaag ctgcatagtt gagaacaaag gcaataatag ctgcaggaag
    39001 gcggtctaaa cgaatcccaa tacttgggag cacataatag ataaaaatca gttgcaagag
    39061 taagggggtt cctcgcataa cccagatgta aatgttaatc agataatgga ggggcttcca
    39121 atggacttgc aaggcaaagg caatcaaaac gcccaaggga atcgaaaata gcaagaccag
    39181 tgcaaagacc tgtacagtcg tgctcgcacc attcagtaaa ctcggtaata tctcaaataa
    39241 ataagacata ctgcacctcc taaaagtaat tgttcctatt atagcatgaa taaacaagat
    39301 taccaagtat ttttgtaaaa agattctacc atatacaaat aaaaaccgta gctatcaaaa
    39361 gagataaact acagttctat atgtttaaac attcttacaa tctctcaaac agttcttgca
    39421 tttgcacatc atctggaacc agttttaagt aagtgtgagc atggactttt gcttcttcaa
    39481 aatgtcccaa ttcacgcaag agatagatat agtgttccag aaattctgga ttgtccttca
    39541 aatctcctgt caactcttga taatgctcat aagcagtatc caaatcgtcc atttcttgat
    39601 aagaacgagc aatcatccac ttggtcaaaa gattttctgg ctcctcactc tgcaagtcta
    39661 gaatatcctc ataacgctcc tgctccagat aaatagtggc taaacgaagc aagatttctt
    39721 ctgtatcctc agcgtcttct tttgcagtaa ggagataatt ttctgcacca ctagcatcat
    39781 gcaattcata agaaaattgt gaagcagcta gcaagaggcg agtttcaaag ggatttttct
    39841 ctaatccttg cttagcgata cgcagggctt cttgaacttg atgttcctta tgtaaagcct
    39901 gactgtaccc atactcatag ccttcaaagt caggagaaat ggtatcaagc tgcttaaagt
    39961 agagggtggc tttttgatat tcttcttgat caaaataaag actggccaac tcaaaagctg
    40021 ttaagtcatc gtattctaac tccagggctt tttctaaaaa ctcagtagcc gtttcaaatt
    40081 tccctaactg agcataggca aagccaattc gttgataggt ggaaatgccc gtttgctcat
    40141 aaatcgagcg attatctaac tgggcatagg cttgaatagc cgcttggtaa ttttccaact
    40201 cactatccaa ctctgccaaa cccaatatca agagagaatc ctctgagtag gtcaaggcct
    40261 ccaataattt ctcacgtgcc acatctgtca aaccttccag ctggtaaagg tctgccttca
    40321 aaaccaaaga cgagacatac cagtcactgt cagcttggat ttcctcaaga taggtaaagg
    40381 cttcttctat ttgaccatcc tcgctagcaa ttgcagctag attaagatga acctctggaa
    40441 aatcctctac aattttcagg taaatttcct tggcctgagg atagaaacca atcccttcaa
    40501 gataagttgc caactcatac agaagattac ttgaatcatt ttctaaagct ttggcgaaat
    40561 aatgctcagc cttagttaaa tcttgctcct ccaaagcctg taacatctgt tgactattgt
    40621 tcactcttga cttcctcacc ctctaattca tatagaccac tgactacctt ataccattcg
    40681 aaaatggctg aaatgacaac cttagcagag gcataaaccg gaataccaag taaaactccc
    40741 cagataccaa acatagatcc tgaagttaac aaaacaaaga gaacattaat agggtggatg
    40801 tttaattgac ttcccaaaat caatggagag acaaaacggc cttcaatagt ttgttctacg
    40861 ataaagacaa tcactacttt caaaagcatg actggaccag caatcaaacc caatactaga
    40921 gcaggaagca tggctagaaa gctaccaaga taagggacca gatttaaaat accagcagta
    40981 acccccagcg taaccgcata gcgtagacca ataatcttga agaagatgat aaacattact
    41041 gctacaataa tagccactgt cacttgccct cgaacatagt tggacaactg ttgattcaca
    41101 tctgatagaa cttgtccaac aggttccttc aattttcttg gaatgaattg ggtcaaatag
    41161 ttacgcaagc ctttcccatc acgcaagaga taaaagagca tgaaaggaac gataatcaag
    41221 gcaacaatca cttgagaagc tccgctaata aaggcactca cccagttgac tgcctgagat
    41281 gaaaccttac ttgccaaaac tgtagcctgg ctagaaaaat tggtcaaaac ttgctctaat
    41341 tgaggtctga aatcatctgg caggtgctgg gctaccaatc cattaacaat cctatctata
    41401 tcttctaagt aaacaggaac gtttcttgca aaggtcaaaa cctgacgttg cagatttgga
    41461 atggcgactg ccaagcccca aatgataaag agagcgatga taacaaagac aatagtgata
    41521 gctataacac gattaacctt atgcttctcc atccaatcaa caataggatt caacaaataa
    41581 tataacaaac cagacaaaat gactggcaac atcacaactg ctaaaaagtc taaaacaggt
    41641 gaaaatagaa aactaatctt acttaaaata aaaagattca gtcccaataa taaggttact
    41701 aaaaataccg taattgcctt gttatctaaa aaccacttga aaaaccaaga taggctaaaa
    41761 tgtttctctt tttgctccat aaatacttcc tttctattgt cctctcatta taccattttt
    41821 gaaacaaaat aactcttttt taaagtgctt acatctaatt ggatatcttt aatttacttg
    41881 tttttgtgat ataatagtct tatctttaca cagaggtata gtaatgaaag aaactgttta
    41941 ttttggaact tatacacgtc gtacttctca agggatttac aaggcagact ttgatacaga
    42001 aactggtcag ctttcaaatc tagaactttt tgcagctgag ccaagtccaa cctaccttgc
    42061 ctttgaccag caccaacatt tatacactgt tggtagccaa gacgataagg ggggaattgc
    42121 agcctatcaa actgacggga ctgtgttaaa tcatgttgtt gaagaaggag ctccccactg
    42181 ttatgttgct gtcgatgaaa agcgtgattt ggtttacgca gccaactatc acaagggaca
    42241 agtccttgtt tataaacgcc aggaagatgg tagtcttcta cttagtgata tggatcaaca
    42301 cagtggccaa ggtccacatg aaaatcaagc ttccccccat gttcactata cagatttaac
    42361 acctgaccac tatctagtga cctgcgactt gggaactgac caagtcatca cctatgacct
    42421 cgatcaagaa ggaaaattat ctaagctcta tacctatcac agcaagccag gagcaggctc
    42481 acgccatatc attttccata accactataa aatcgcttat ctcatttgtg aactcaatag
    42541 tactatcgaa gttttaatct acgatggcgt tggcgaattt gtacgtatgc aggttatttc
    42601 aactttacca gaagcttacg aaggctttaa tggaaccgct gctattcatc tctctaaaga
    42661 cggtaaatac ctctacgctt ctaaccgtgg ccatgattct atcgcagtat ataccatcct
    42721 tgcggacggt agcttagagt tattagaaat cgttccaacg catggtcaga ctccacgtga
    42781 ttttgatttg acacccgacc aaaaatttct cattgttgtc catcaagact ctgacaatgc
    42841 aactgtcttt aaacgtaatt gtgacaatgg tcgtctagca gaactctcca acgacttcca
    42901 tgttcccgaa gcagtctgca tccgttttgc tccttaaaac accataaaaa atgaacttgg
    42961 tattttcaag ttcatttttt cttatagtct atttccgaca ttaatacggt taatggcacg
    43021 ttgcaaagca atcttagcac gacgttcttg gtcaatcaaa tgtttgtctt gtgcttcttc
    43081 aattgcacgt tctgcacgaa gtttggcacg ttctgcacga ctgatatcga tatcacgagc
    43141 acgttctgca gagtcagcga cgattgtgat catatcattg gcaatttcaa taacgccacc
    43201 gtttactgca atccagttca cgtgatcttt atcatcgata cgttttacct ttacttcatc
    43261 aactgctaaa accgcaatca tattttcatg tcgtggcaag atccccatct caccatccag
    43321 agttcgaacc gatacatagc tggcatggtg atcatagacg agaccatctg gtgtcacgat
    43381 ctggacagtt aactgagcca taggtcacct cttaaaatcc cattttttca gcttttgcaa
    43441 tcacatcttc gatagaacct acaccacgga aggcatcttc tggcaagtgg tcgtatttac
    43501 catcaaggat ttccttaaag ccacgtacag tttcagcaac tggaacataa gaacctggct
    43561 gaccagtaaa ttgttccgca acgttgaagt tttgtgacaa gaagaactgg atacgacggg
    43621 cgcgagcaac caaggtcttt tcttcatcag aaagctcatc cataccaagg atagcaatga
    43681 tatcttgcaa ttcatggtaa cgttgaagaa cacgttttac ttcagcagca actgcatagt
    43741 gctcttctcc aacgatttca ggtgccaagg cacgtgagct tgaagcaagt gggtcaacgg
    43801 ctgggtagat acccaattgt accaacttac gttccaagtt tgttgttgaa tctaagtgag
    43861 cgaaggctgt tgctggcgct gggtcagtat agtcatccgc tggcacatag atagcctgga
    43921 tagaggttac agaacccttc ttggttgatg tgatacgttc ttgcaattga cccatttccg
    43981 tagcaagtgt tggttggtaa ccaacggctg atggcatacg acccaaaagg gcagatactt
    44041 ctgaaccagc ctgagtgaaa cggaagatat tatcgataaa gagaagcacg tcttggcctt
    44101 ccacatcacg gaagtattca gcgattgtca aaccagtaag ggcaacacgc atacgtgctc
    44161 ctggtggctc attcatctga ccaaagacca tggctgtttt ctcgataacg cctgattctt
    44221 tcatttccca gtaaaggtca ttcccctcac gagtacgttc cccaacacca gcaaatactg
    44281 aaataccacc gtgctcttgg gcaatgttgt gaatcaattc ttggattaag acagttttac
    44341 caactccggc accaccgaaa agtccaactt taccaccttt aaggtaaggg gcaagaaggt
    44401 caataacctt gatccctgtt tcaaggattt cagaagaggt agacaactca tcaaaagttg
    44461 gagctttttt atgaattggc tgacgctctg cgtcttctgt aaaaggagct tccaagtcaa
    44521 tggtatctcc caaaacgttg aagacacgtc ccaaagtttc tttacctact ggtacagaga
    44581 ttggacgacc tgtgtccaat acttccattc cacgagtcaa cccatctgtt gattccatgg
    44641 cgatagtacg aaccatacca tctcctaact ccaaggctac ttcaaggacg atttttgttt
    44701 ttctttcgtc atttttgtag acgacaagtg cattattaat ctcaggaagt ttttcccctg
    44761 ctgcaaacaa aacgtctaca acgggaccga taacctgagc aattttacct gaactcatct
    44821 ccttctccta ttctatataa gatactgtcg gttcctagct caactaggtc ctaagttcat
    44881 tttcatacga gctggactag agcctattct aaggcactag cacctgctac gatttctgta
    44941 atttcttgtg taatagccgc ctgtctggca cggttatact gaattgtcaa atcattgatg
    45001 actttcttag cattatctgt cgctgtttgc atggctgtca tacccgcagc attctcagct
    45061 gtcttggcat cgataatggc accgtaaatc atactttctg caaactgagg caacaactgc
    45121 tccagaattt cttctcggct ggtttccaat tcaaaagtca agctgtactc ttcatccgct
    45181 tcatttggat ccaagtcaac aatcggaagc atttgttcca cacgcatttg actggttagc
    45241 gtattgacat ggtggttgta gcaaacataa agctcatcaa agagttcatt ttggtacatt
    45301 tcaacagttt ttgaaataat cttacgaact tgatcaaagc taggttggtc tgccaagcca
    45361 cgtaattcat aaagtggttg aataccgcga gccttaaaga aatcagctcc catcccaccg
    45421 atacagatca tttcaaaacc tttaccgtct gggtggtatt cttctttcaa ctccataaca
    45481 gctttcaaaa tagaggaatt ataacctcca accaaaccgc ggtctgaagt gataacgata
    45541 tagcctgtct tcttcacaga acggctaatc aacatcggat tagttgaagc accagctcca
    45601 ttaccatgaa ggatatctgt caaaagttta cgcactttct gagcgtaaac ttggaagttg
    45661 cgagcagctt cttcagagcg acctagctta gcagccgata ccatttgcat ggcattagtg
    45721 atttgactcg tattttttgt tgaggcgatt tttgttttaa tatcatttag agacactgcc
    45781 atctgacacc tctattctta ttggaagcta gattgattga gaaactctgt aatcgcagca
    45841 tccaagactg cttcttctgg caagtctttt gtatcacgaa tggtttccaa aatctctgga
    45901 tgttgagcat caaagaaggc atggaactct tcctcgaaac gaacaatatc atctactgga
    45961 acagtatcca agaaaccatg tgtcaaagca taaagaatgg ttacttgttt ctcaacaggt
    46021 aatggtttgt gaacaggttg tttcaagacc tcaacggtac gacgtccacg gttcaactta
    46081 gcctgtgttg ctgcgtccaa gtcagaacca aacttagtaa aggcttccaa ctcacggtat
    46141 gaagcaaggt cgatacgaag tgtaccagca accttcttca tggctttgat ttgtgcagaa
    46201 ccacctacac gagatacaga tgaacccgca tcgatggctg gacgaatacc tgcattgaag
    46261 aggccatcgc caaggaagat ttgtccatca gtgatagaaa tcacgttggt tgcgatatag
    46321 gctgagatat ctcctgcttg tgtctcgata aatggtaggg ctgtaattga tccaccacca
    46381 agttcatcag aaactttagc tgagcgctca agcaaacggc tgtggagata gaaaacatcc
    46441 cctgggaagg cttcacgacc tggaggacga cgaagcaaga gcgacagttc acgataagct
    46501 accgcttgtt ttgatagatc atcatataca atcaaaacat gcttaccttg atacataaat
    46561 tcttccgcca tagcaacccc agcataagga gctaggaaga gcaatggaga tggttgtgaa
    46621 gcagaggctg tcacaacgat tgtgtagtcc aaggcaccgt actgacgaag tgtttctact
    46681 tgcgtacgaa ctgttgattc tttttgtcca atcgcgacgt agatacagat catatcttga
    46741 tctttttggt tcaagattgt atcaatcgca atggttgttt tccctgtctg acggtcaccg
    46801 ataatcaact cacgttgacc acgaccaatc ggtacaaggg cgtcaatagc tttcaaacca
    46861 gtttgcaatg gttctgaaac agacttacgt tgcataacac caggagctgg tgcctcaact
    46921 ggacgagttt tatcagtgtg gatttctcca agaccgtcaa ctggacgacc aagcggatcc
    46981 acaacacgac caatcagact ttcacctaca gggacttcca tgattttccc tgtacggcgg
    47041 attgtatcgc cttcacggat atctgtaaag tcacctagga tgataatacc aacgtctgtt
    47101 gactccaagt tttgagccat accataagag ccgttttcaa aattcaacaa ctctccactc
    47161 atggcatttt caaggccgtg agcacgcgcg ataccatccc cgatataggt tacaacacct
    47221 gtttcagtca catcaaaatt gggtttgaaa ttttcaattt gttgcttaat taaagcgctg
    47281 atttcttgtg cgttaattgc caaaagaaca ccactttcta tttcaaattt tctttaacaa
    47341 ctttaagttg ttgtttaata ctcacatcaa ttgtcttgtg attggcaaaa atgacaaaac
    47401 caccaatgag actttcatcg atttgttctt ttacactcct tactttcaga gacatttttt
    47461 tctcaatcaa aggtagcaaa cgagtcttct gttcatcagt tagaggatga gcagacgtaa
    47521 tcgtcacttc aaatcgattt gtttcttttt caagtcggtt caagcaatct acaagcacat
    47581 cataaaaaag atttgctctg tgattgtagg ccagaacctg gataaagttt tgtaataaag
    47641 gtgacacaga atcttggaaa aaagcaattg ttttttcctt atccgactcg tctactgcca
    47701 cttgttttaa aaaagaaggc agacctgttt tttcaacaac ttgcttgatt tgagtcaagt
    47761 ctgaaaagat acggtcttct tctccttttt caagtaccaa ttggacaaaa ggcatgctgt
    47821 atttttcaat tacctttact gttttcttgt ccattaagct tctcctagct gatcgatata
    47881 ctgatcaatg agtgctttat gggcatgact gtcaaggttt tgtgagatga ttttaccagc
    47941 taagctgatg gtcaaatctg cgacctcacc cttaacactc tgtaaagctt ctactttatt
    48001 ttgagcaatt tcttgattgg ctttttcttt taagtgtcct gcttctagtt tagcatctgc
    48061 taagatatta gccttacttt gctcagctgt ttcctttgca ttttcaatga ttgtcttagc
    48121 ttctttacgg ctaccagcca attcatcttc gcgtttttga gccaatactt ctgctttttg
    48181 acgggcttct tcagctctgt caatatctga agcaattttt tcagctcttt cttcgaaaat
    48241 gcctgtaata ttagaccatg caaatttttt aatcaagact agcaaaagaa taaaagagcc
    48301 agtgattaaa ataaaattac caattaattc acctactgtt acgtgcatca gttactcctt
    48361 tctattcctc ttcaatatta atcttattcc ctaaatacac agatgtcaaa agagtaaaaa
    48421 cataagcttg gatgcaggaa ataaagacag aaaatgcagt ccaagccaaa ttagctccaa
    48481 aggctactgg ataccaataa atagcttggt gggaaagaag aagtaacaaa ctcgtcatga
    48541 cctctcctgc aaagatattc ccaaaaatcc gcaaagccaa agataagaag tttgtaaatt
    48601 cttccaagat attcatcggt atgacaaaaa caggactcat aaaagatttt atactttttt
    48661 taaatccacg acgacgaacg ctttctatat gtgtcaacaa aatgacaaga aaagataagg
    48721 ttaagtcata cggtaaatta gcggttggcg aactccacca gttagtccca tcgatcgttt
    48781 gaagctttgt cattaagcca aggttattgg caatcaccat gaaaaggaat aaacaaagga
    48841 aaaagagtga gtaatctttc atgtagcgcg aaccaatgtt aggttctgta aatccaataa
    48901 caaagtcata gacatactca agtacatttt gctttccttt gggtttcaag gtcatattgc
    48961 ggcttgccca ataaataaag acaaaaataa ctcccacaat caacaaagtc atggctaaca
    49021 tagtcagatt gaagataaca ggaccaatag agatgattgg attaatactt tcttccatct
    49081 aaaatcctcc cttttcttct cgttccatgt atttatttga taataaatga gaagacaaga
    49141 gttacaaaga aagttccttc aataaaggca acacctaaaa acatcaaact acgaaactca
    49201 gaaagcatat ctggttggcg tgctactgat ttaaacagtc cattcatcaa taaaccttca
    49261 ccgacagata cgcccataca ggcaatacat aagcctaaaa atgttaaatt cataacaaat
    49321 tctcctttaa aataaaattt acttacttag tgtagtccta aaatttaaat ttgtcaactt
    49381 ttaaccgcta ttggaagcgt ttaataaaaa ttatttccat tttgctaaat ttcaagttca
    49441 agttagccat ccagaagtct tctctgggtg acttgtagtc caagcatttt ttaggatagt
    49501 tgttaatcca cttttcgatg aatgcgactt ctttgggagt cattttcttg gttcccttag
    49561 gtaaccatct acgaatgagc ctgttgtgat tctcattagt tcccctttcc caagaggcat
    49621 agggatgtgc ataataaatg tgctcctcag aaaatacatt agacaagcga ttgaattccg
    49681 ttccattatc tgccgtgatg gaaagaatct tgtgttgttt taagatgagt tttagagcct
    49741 gattgaccac ctcagcactt ttatttggaa tcaatcggat gatctgatgt ctactttttc
    49801 gatccgtcaa gacaagcaag cagtagtttt tcgctctcgt aagtagaacc gtatcaatct
    49861 cataatgccc attctccaag cgaaaattga tagcttcagg ccgctgttcg atggattgac
    49921 cagcaggttt aaagttggtg ctggcctgtt tcttaagcgc ttttcctttt ctagggtaaa
    49981 gcagatcctg cttgctttac cccaattttc catgatgaat ccaatagtaa atggttgaaa
    50041 ttcccacgtt aaccccttta gccataacca tcatttcagg caaaaatttt tggttatgat
    50101 agtggagaat cttttccttt agttccttgg tcacgcttga tctcttgacc gagtgcttgc
    50161 gattattttc ataagactgt tgagcatagt cggcagaata aacctctttg aagcgccctt
    50221 ttccaagaca ttttcggact gtcctacgct tgattttagt gtggatagtt tgaggagctt
    50281 ttccaagtag agaggcaatt tctctatttg attttccttc ttttttccat ctttcgatta
    50341 agcgacggct atcgattgtc aaatgtttac cttttgtagt ataattgtct tgcatttctg
    50401 tgcctttctt gtgtttgtgg ttgaacaaca agtataacac agaggtgttt tcttatgcct
    50461 acaagagctt tcattatttc cattttcttt cggatttcac tctattctga aaaacttgtg
    50521 tatatttact gaagctagca agtcttacct gtaaatttaa tgaaagcaac acaaaatccg
    50581 agaggggaat ctcggattaa tgtcaattta aaaagataga gagtttttag tttaaataaa
    50641 ttgttttaaa atatcaacaa catcacttct tttcttaacc tgataagcct tgattcctaa
    50701 ttttggagct acgattatat tgtcctcaat atcgtctaga aagacacaat ttctaggtta
    50761 taactggtat ttatcgatag ttactcatat acatcagtcc acctccatac ttatgtgcga
    50821 gcctctcttt gtattatacc tccatactca ccttacagat tcttttggta ataatatctt
    50881 tgcctaatgt agagatagtc ttacaaagaa aaaacttcct tgtagccatg tttctgataa
    50941 aagtccggtg cctggaactg ataagtattg acaaaggcaa aacaacaatt tcgattctta
    51001 gcttcacttt ctgcctgttg caatagtttt gaaccgattc cttgccctcg cagttcctct
    51061 tttacaaaca aatactcgat ttctagccaa tttccaaaag tctctgctat caaacccgca
    51121 aggagattgc ccttttcatc ttcgacataa agattaagtg gctcactttc agcctcttcc
    51181 ctttttgaac ggttataaac acgaatcaga ttccctattt cttgcgattt atgtgattcc
    51241 ttattttcca atctaaagta taatgaaatg aaataaaaca tgcgcaaatc gattaaggaa
    51301 tttaatctaa tttctaataa tgtcttagaa atcaaagttt actattttaa cttcaatgca
    51361 ctatacatct aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc
    51421 tcaaaacact gttttgaggt tgtagataga actgacgaag tcagctcaaa acatggtttt
    51481 gaggttgtag atgaaactga cgaagtcagt aaccatatat acggcaaggc gacgctgacg
    51541 tggtttgaag agattttcga agagtagcaa aatggaaaaa ggagtgagtg aagcacatcg
    51601 cctccccact cctttttctg tttttaggct gttttttcaa ccttcaagat ttttacatca
    51661 tagctaccaa caggcgtttc aattgttgct gtgtcacctg ttttcttgcc aatcaaggcc
    51721 tgcccaattg ggctttcatt tgaaacctta cctgcaaagg catccgcacc agctgaacct
    51781 acgataatat aaacttcttc ttcgtcctcg ccaatttctt ggatggtgac tgttttacca
    51841 atcgctactt cgtcctgggc aactgcgtcg ctattgacga tttcagcata gcggattttt
    51901 gtttctaagc tagagatttg tccttcgaca aaggcttgtt catccttagc tgcttcgtac
    51961 tcactgtttt ctgaaagatc accgtatgaa cgggcaatct taatgcgttc taccacttct
    52021 ggtcgacgaa ccaatttcaa ttcttctaat tctttttcaa gtttttcctt ttcctcaagg
    52081 gtcataggat atgttttttc tgccattttt ctcaactttc ttctgataat attttctaaa
    52141 gaaaattatg tgacgtatca cataatttta gtttgtttag tttaatttgc tgttgacatg
    52201 ttcagcgaca ttgcggtcgt ggtcttcttg attgttagca tagtagacct tgccttctgt
    52261 gacatctgct acaaagtaga ggttatcgct cttagtttga ttgatgcttg actcaatcgc
    52321 atccagactt ggactatcga ctggaccagg catgagacct acatttttat aaacattata
    52381 aggtgaatca atgttggtat caatcgcaac atcctcagct agactgatat tttgccccag
    52441 ttttccttgg gcatacaaga ttgcaatatt actttgaagt ggcatatcac gatttaaacg
    52501 attgtagaat acacctgcaa tgagcttacg atcttctgtc ttggcacctt ctttttcgac
    52561 caaggaagca atggtcaaca actcattgac agtcaaattt ttagatttga tagtactata
    52621 gtaaggagat aggttcttat ccatagcagc taacatctca tcaatcaagc tctcaatagt
    52681 tgtgctttcc ttgatagagt atgtagctgg gaaaaggtat ccttccaaac gataacgcgc
    52741 accgctgtct tttacaggca aactttccag taaagtagga tatttcgcta ctgcttgact
    52801 gataaacgtc tcatcttgaa ctttagccaa gaaagcctcc gctgtcaaag actctttgaa
    52861 gtcaccttgc aattgaccca cagcttgagc aatctgatcc aaggtataac cttctggaat
    52921 tgtcaaagtc gcaagtacag gttcttgcgg ttcatctgtt ccaccttttt gcaactcttt
    52981 gagtaagtct tctgtactca tactcttttg caaattgtag taacctgctt tcaagtcggt
    53041 ataattttta tacttggcat aaaaactaaa aatcagacca tgctttacca aaccagcttt
    53101 ttcaagcgtc gtaccgattt cttgaacgtt tgaaccttct ggaattccaa ccgtcacata
    53161 tttcttagaa ttagcatcga taggtaacaa agaatctagc acgtactggt aaccaaagta
    53221 accacctgct gagagcaagg caaggaatac aaggaatgaa atcacaaaag ctttcacatg
    53281 tgacttcttc tctttcttag gattaacggg ttttgctcct tctctacggc tacgacgtga
    53341 tgtatcgctg atgatatcca ctgtttctgt agcaggcgta ggtgtttctg gacctgcttg
    53401 ttctgctttt ttctctgccg tcgtatagga aacagctacc cttgttgggg tttcattgta
    53461 ttctctttca agtttcttag gtctaacagg acctggacct ggtcttgatc cactttcttc
    53521 cgctggagaa gaaggtacat cttgacttgg atgacttgga acaccaggag tttctctttg
    53581 aatctcatct gctggagaag ctggtacacc ttgacttggg tgagtagaca cggtaggagc
    53641 ttttctcata atctcctcta ccgttgacaa ggaatcagcc atgagttctt cagctgaagg
    53701 ttcatttgca ggagtgcgaa ctactgcctc atcttctttc agaacttcat catagccttt
    53761 tactttttct aaatctctca gaatctgctc tttaaagctt aatttctctt cttctcttga
    53821 cttttcactc aaaagttttt cctccttgtt gataatccat aatattatat cttaaaagtc
    53881 caaaaaaagc aatctatgat acttttccta acttattttt tcatttccca gaccatatca
    53941 taccatgttt cccctgcaaa ggttgactgg gactggcctt cgttgacaaa tccatgtttt
    54001 tcatagtagg cgatgagata gtcatgacag gttagattaa tgccatctct ctcatcttca
    54061 agagcaactt ctttcaaggc tgtcagcaat ttctgaccca gtccgagtcc ctgtgcctcc
    54121 ttggcaatag acagacaggt cacagagata taaccaccag gctcatgact atagtctttt
    54181 atttcttctg taaaagactg gtcttgcaga tggcggtgca ggccaactgg tccttcgata
    54241 taacccatga ttcttccttc tttttcagca accagaaaag aggtctgaat ttctctcaaa
    54301 tgtgcttcaa agacagaagg aggaatggct tcttcgaccg aaaaattttc aaattcaagt
    54361 tcaacaatcc gatccaaatc ttctaatctt gcttgtctga ttttcattgt tcctccagat
    54421 aaaagggatt aaaccaaatc atactatagc cctggctagt tgcatagagc aaagttgctt
    54481 cttcatcaac aaaaccgttc atttcaaaat aggaaagcag ctcatcagga ctctccaaac
    54541 gaatcccttt gtaatccagc tcaactgcca tctctttcaa ggctgcaaga agaagtgttc
    54601 ccaagccctg tctctgatgg tcagactcga tgactaaaga atgtactttt agatattgcg
    54661 gattgtctga ctggggactt gataaaatat agcctaaaag ttgattttca tccctagcta
    54721 gaagaaaggt atccgcacac ttacggatac tttcttctaa aatatgggaa agttgctgct
    54781 tttcagctgg aaaagacgag gtctgaagtg cccctatctc aggcaaatca gacttgcttg
    54841 cctgaatgat cttaattgga atttccatgg gaacatccta ttgaacattg cttgtcaagt
    54901 tagacaagag acgctcaaat gagtattcat aggtttggat gtctcctgct cccataaaga
    54961 cgtaaacagc attgtcatgg tctaggagcg gagaaacatt ttcaacagta atcacttggt
    55021 gttttttgtt gattttgttg gctaggtctt ctaccttaac gtcaccatga tctacttcac
    55081 gagccgagcc ataaatttgc gctagataaa cagcatctgc ttggtttaaa gcatgggcaa
    55141 agtcgtccaa caaggcaatg gttcttgtaa aggtatgcgg ttgaaagact gctacaattt
    55201 ccttgcttgg gtatttctga cgagccgcat ccaaggtcgc aataatttct gttggatggt
    55261 gggcaaagtc atcgataatc actgtatcat tgacaatttt ctcagtgaaa cgacgtttaa
    55321 caccggcaaa tgttttcaag tgctcacgca ccaagttcaa atcaaatcct gctgtgtaaa
    55381 gaagaccaat aacggctgtc gcattcatga tattgtgacg accaaaggtt ggaatgtgga
    55441 attgccccaa gttttgtcca cggaaatgaa cggtgaaggt tgaaccagtt attgaacgaa
    55501 gaagatcact agctacaaag tcattgcctt caacttcaaa accataataa taaattggtg
    55561 catcagacgt aatcttacgc aattcagcat cttcaccata gacaaaaaga cccttggtga
    55621 tttgtttggc atagtcgtta aaggcattaa aaacatcctc gagacttgtg aaataatctg
    55681 gatggtcaaa gtcaatgttg gtgataatag agtattctgg gtggtaaggc atgaagtgac
    55741 gctcatattc gtcagattca aagacaaaat atttggcatt ggccgaacca cgacctgtcc
    55801 catctccaat caagaagctg gtatctgtaa tgtgagacaa gacatgagac aacatacctg
    55861 tcgttgaagt ttttccatgt gctcctgcta ctcccatgct aacaaagtca cgcataaagc
    55921 tacctagaaa ctcatggtaa cgtttgtagc tgataccatt ttggtccgca taggcaattt
    55981 cgacgttgtt atctggacga aaggcatttc cagcgataat ttccatatca ccgtctagat
    56041 tcttttcatc aaaaggaaga atggtaattc ctgcctgctc aagaccgcgt tgggtaaagt
    56101 agtacttttc aacatctgat ccctgaacct tgtgccccat ctggtgcaac atcaaggcca
    56161 aggcactcat ccctgatccc ttaattccga taaaatgata tgtctttgac atgttttctc
    56221 ccctattctg tcattctggt cagattcaac tcttgggcaa cccgacgttc ttgttctgtt
    56281 tgtttacttt ttttattgta gatttggctc ttctttagaa aatcataatt gtttttcttt
    56341 ggagcaggtg ctgacacttc ttcattcttg gtagggatag aatgaacttc ttccgccaag
    56401 atataatgag actgggtcaa tttttggcta tatttgacaa attcaccagg attttccttt
    56461 tggaaaggag ttgtcggttg attgccctgt ctaactagac tgggctgaga atgacgtctc
    56521 gcaaggctga aatcctgagt taggtagtta gcagagcgtt tctttttcaa gtccgcacgc
    56581 gcttcttcac gcgccacctc cgcatagctc tttccttctt ttttaacccc taaaggagcc
    56641 tttttaggtt tttcgacttg cttttcaatc ggttttactg gtttttcttc agcaatagga
    56701 gcccattcta aataattttt atctcgatac tcacccttga tattactgat cagatcagac
    56761 tcatcataga gattcatgac tggcatttca gtcaacatga cctcgtcatc tgacaccaat
    56821 ggaaatcgtt cttgtttcat tttctatttc ctttcaacac ttcattatag cgtattgtct
    56881 tgatttttca agtgctggct tcagaaattc ccaaaatttc tctaatttct gctagggtca
    56941 gactaccacg tgactctgtg ccgtccaata cttgtgacac cagatgtttc ttttgttctt
    57001 ggagttcctg aattttttct tcaatggttc ccttggtcac caagcgatag acctcaaccg
    57061 tttcttcctg acccatccga tgggcacggc caatggcttg cgcttccacc gcaggattcc
    57121 accaaaggtc aaccaagatc actgtatctg cacctgtcag gttcagaccg accccaccag
    57181 ccttgaggga aatcagaaag gcatctcttt ctccttggtt aaaggccttg gtcatgtctt
    57241 gtctttcctt ggctggggtt gaacccgtaa ttttaaagga agtcaggccc aagtctggca
    57301 gttcttgttc aattttttcc aacattccct tgaactgaga gaaaatcaag acacggtgtc
    57361 cgccgtctgc cacctgtacc agtaggtctc ggagactatc tagtttgccg ctggctccct
    57421 gataatcttc cataaacagg gcaggagtgt cacatatttg acgcaagcgc atcaaaccag
    57481 ataaaatttc cacacgactt cgctgaaatt cctgttctga cacttgagcc agatggtctc
    57541 gcatctgttg taactgggca aggtaaatag ccttttgctg gtcttccagt tcatttttat
    57601 aaaccacctc aatcaagtct ggcaattcag tcagaacttc ttctttcttg cgtcgcatca
    57661 cgaaaggctt gataaactga gccactcgct ctgctggcaa tttcataaat tctttcttgc
    57721 ttggcaaaag tccgggcatg acgatttgga aaatagacca caactcaccc agatggtttt
    57781 caatcggagt tcctgacaag gcaaagaccg acggcaccac aaattgtctc aaggtctggg
    57841 caatcttggt ctgggcattt ttcatgacct gagcttcatc taagaaaagg aagtcaaagg
    57901 ccatcccctg ataaagctca ctgtcctgac ggaaggtggc atagctagtc acatagattt
    57961 gatggctctc ggcaagaatc tcctcacgac ttgctttcaa accatgaaca acagccacat
    58021 ccaactgtgg ggcaaatttc tgaaactcat ctgcccagtt gtaaatcaaa cctgacggag
    58081 cgagaatcaa aacccgactt tcttttgtca cttgactagt caaaaaagca atggtctgaa
    58141 gggttttccc aagtcccata tcatcagcca aaatcccacc aaaaccataa tgatggagca
    58201 tctgcaacca gccaattccc ttttcctgat aatctcgcaa gtcagcctga acctgagttg
    58261 cctgtcgagg aaagtcctct ggatgtgtca aatcctgggc catattctgg aattcttgtg
    58321 aaaaagaaac acggtctcgc ccttcaaaga gatgagctaa actgtaggcc aaggatttcc
    58381 gagcctgcaa ggtcccatct tttaattcaa attgccccag ttcctgtaga ttttggcgaa
    58441 ttttcttggt ttcttcatcg aaaaagtaaa cttgattaga cgaatcaata taaaaatcct
    58501 gattggcaac caaggcctgc atggcttggt cgatttcctc ctgggcaata tcttgaaaat
    58561 caaactggat ttccaagaga cctcccttgg aggcaatctg cacctgagga ctcgctaggc
    58621 tataaagctc ttctagttta tctgataggt caacatgccc gagtttttca aagactggaa
    58681 tgatatcatg aaaaaaatga tagacagact ccgcttttaa ggcctgacgc caagattgaa
    58741 aatcggcttc aaagcccgca gccaaacaga cttggaaaat tctttcttct aagtccgcgt
    58801 cacttgaaaa tggtaattct tctagctctt gtcggctaga tacctgtcta tttccataat
    58861 caaactgaat ttctaaacga atccgattat cttcttccct gtcaaagtaa aaagagggcg
    58921 caaaagtttt gatttgtaga cgttctggag ctgaaacggt gcccatctgg ataaaaagag
    58981 tcagacagga ggccaatttg tctcgatcac tgctatcaaa ttgcaggtat ttctttcctt
    59041 gttgacccac aggtaacgct ttaatttcct tgagaagacg catctgctgg tctgttaaaa
    59101 aataaacctg acctttatgg aaaagtactg ctccctgata aaagacattg accctaggac
    59161 tctcactgat ttccatttca aaatagtccg agtattctgt tactgtaaag gcaaatagat
    59221 tggcatcagc atgcatatcc tgaaaaagca gggtttggta gctatccact tgatggtcaa
    59281 attgaaaatg gggcaaggcc atcagtaaat tcacaccctg ctcaaaaaag gtcagaggga
    59341 aaaagaggtg ccgaccttgg ttttggaaaa agaggtctga aaccagccct tcctccgtta
    59401 gtccgtgcaa gaaagtcaaa agttcttggc tggcatcatc aaaggcttcc caagaaagag
    59461 actcctcata aatcttgcca atcatatacg actttctctg ctcgacaatc cttaaaaaaa
    59521 gtggaatatc ccgaatgaca tagtattttt ggctattgat ttgaccgatt ctcagagtcc
    59581 acaagatatg attggttcct gcttccacct gacccacagc tgataactca taggcgcatt
    59641 ctgattttgg agataaaatt cgatccaaaa acttgccacc caaggtcacc ttggtttcaa
    59701 cagcctcttt ttcttcatga ccttcttcca gactccacaa gatttcctga ccacgctcat
    59761 catttttcag aaaatgctct agcgctgcca aatgcacaca gtaacccctc ttttgaaaaa
    59821 aatcacaggc acaaaaaacc aaatcatcct ctaaactata gcgcagttct tcttctgcaa
    59881 cgcgagcgta gagccgattg ttcttttcct tgatgatatc aaccttacca gtttcataaa
    59941 gggcaacacc ttcgatacga attttccccg gaatcaattt agccatattt tcacctttac
    60001 cttatctttt tattatacca tattttcgcc tatgaaaata gccttctagg aagacttttc
    60061 tcctagaagg ctggattttt aacgtttggc aaaagtagcc acaatccgct gacagacttc
    60121 ttgcaacaga gatttgggca tagctatatt gatgcgggca tggagacttc cttcctctcc
    60181 aaaatccaaa ccacggttga ggataacctt ggcttcattt ctcaacaact cttgcaatgt
    60241 ttcatcagtc aggtcataag ctgaaaagtc aagccaaatc aagtaggtac cttgcggttt
    60301 catgaccttg attttagtct cttttccaaa tagatccacc acataattga tgtggtcttc
    60361 aaagacttgc ttgagttcct ctagccaatc tttaccgtat cgataggcag cttctgtcgc
    60421 caaataaccc aagcctgaaa tttcatgctg attattggcc aacaggcgtt tctggaaagc
    60481 tagtctcaac ttaggatttt caatgactgc ataggaattt tttgttccag caatattaaa
    60541 tgttttagtg gcactgctca agacgatagc aaaatttttg aaggcaggat tgatggtatt
    60601 gaaagactgg tgtttgtgac caaagagggt caaatcttgg tgaatctcat ccgaaactaa
    60661 caaaacaccg tgtttttggc agagttggcc aatcttctcc aacacttctt tttcccaaac
    60721 acgtccacca ggattgtgag ggttgcaaag aatatagagt ttaacctcct cttccaccaa
    60781 atccttttca agttggtcaa agtcaatctc aaacagacca tccttttcca ctaaggaatt
    60841 agtaatcaat ctacgattat tcaacttgac actgcgagca aagggtgggt agacaggcgt
    60901 gttaattaaa accgcctcgc cttcttttgt aaaggtttga atagctgttg agatggctgg
    60961 taccacaccc tcgataaaga caagagcctc tttgtcaaag ttgtaaccgt attgtgtagc
    61021 ttcccacttt tgaacttcct taattaagtc ttcactggca taggtataac cataaaccag
    61081 ttggtctgcg taagtttgca cggcttggcg gatttcaggc aagaccacaa agtccatatc
    61141 cgctatccaa gctggtagaa cttcactatc cgtttctgtt tctttccatt tataggtatg
    61201 gtgccctaaa cggttgggca ggcttgtaaa atcatatttt cccatctttg tcttatcctt
    61261 ctaaggcttg gcgcaaatct gcaatcaaat ctctagcatc ctcaatccca atagacaaac
    61321 gcaagaggtc atctgtcaaa ccataagaat ggcgtacttc tgctggaata tcagcatgag
    61381 tttgagtcgt tggataagta ataagacttt ccactccgcc caaactttcc gcaaaagaga
    61441 agaccttgag actgttcaaa atatgaggaa tgcgtgtttc atcggctact ttaaaggaaa
    61501 tcatgcctcc acgaccagtg tagagaactt ccttaactgc tggagaatcc ttcaaaaagg
    61561 caaccacttc ttgggcgtta gctgttgagc gctccatacg aagagacaag gtcttgagac
    61621 cacgaagcaa ctggtagctg tcaaatggag acaagactgc ccctgttgta ttgagattgt
    61681 aaaaaagctt ctcgtatagt tctaaactat tggtcacaac cactccagcc aagacatcat
    61741 tgtggcctgc tagatacttg gttgctgaat ggagaacgat atctgctcca tcttcaatcg
    61801 gacgttggta gatagggcta tagaaggtat tgtccaccac cactttggca cccttagcat
    61861 gagccaattt tgctagtttt tcgatatcaa attccaacat caagggattg gttggggttt
    61921 cgatatagag aacatccaca tccttttcta actcggcaat caactcttct tctgtattgg
    61981 cataggtaaa atggaaacga ccttcctgct ccacttggtt aaaccagcga aaagaaccgc
    62041 cgtaaagatc acgcactgcc aagaccttac ttcctactgg aaagccgcta aaggccagta
    62101 caatagctga catccctgag ctagtcgcta aggcatagtc tgctgactca atagtcgcca
    62161 agacttcctc agccttacta cgagttggat ttttagtgcg cgtatagtca aacccagtag
    62221 atcgaccaaa ctctggatgc tgataggtcg ttgaaaaatg aagcggtgtc accaatgcac
    62281 ctgtcgcttc atctgactta atacccgcct gggccaaaat tgtgttaatg tgtaattcct
    62341 tgctcataca atacctccaa atctatagta actattgtac cacttatttt catcaactca
    62401 ttttcttctt ttcaagagct agttatagtt tcaaactata taaaaaggga gtttttcctg
    62461 ctccctttaa tagactataa aatggtgaat ctcaaaagac acttcactct atcatttgct
    62521 cctgcacaaa acgagcataa cgctcatgat tttccagtag ttccttatga gttcctgagc
    62581 cagtgatttt cccctcctct aagaagaaaa tacaatccac atcttttacc gttgacaaac
    62641 tatgcgctat aatcacaacc gtcttctcct ttaatacaga atagaggcta ctgataatcg
    62701 catactcaga atccgcatca agattagcag tagcttcatc aaatataaga atttcagcat
    62761 cttttaagta ggttctagct atttgaagtc tttggctttg cccccctgac aagaatcgtc
    62821 cgcgttcacc aacttcagta tctagtccct ctttcatgga gcgaatctca tcacctagtg
    62881 atactaagtc tagcactttc atcaattcat catcaattac taagcgattc aaaccgagac
    62941 aaagattgtc acgaatactg ccagataaga ctgcattatt ttgtgaaacc caagcgattt
    63001 tacttctcca ttcttttaag ttaaaatcat atatacttga ttgctccatt agaatatctc
    63061 ctgaaagcgg tttataaaac cgctctaaca aacgcacaat cgttgatttt cctgatccag
    63121 atggtccaac aaaagcaatt tttgcccctt gaaaattgaa caagtaatat cctttaagac
    63181 aggtcgattt tcatcataac caaaatagac atggttaaaa ttcaaccctt gtcctgatac
    63241 cgattttcct ccctcaaatt tttctttagg aactgcaagc aagttatcca gtgcaactga
    63301 agatcccttg ctcctagaat aaacagttac aaaattagct atattactaa taggattaag
    63361 taattgaaag aggtaaatca aaaacgaaac caaggttccc acagatatat atcctgcgct
    63421 gacccgataa cccccatagg ttagcatcac agctatagtc gcaaagataa ataagagagc
    63481 aaacggggtc tcaaaagaag taaccctatc tgatttcagt gaattgtttt gtaccctttc
    63541 aatacaatta tccaaaacat cctgtacact tttctctgct tggttagtct taattaattc
    63601 atgttcttga atcttttcag tcaattgccc tgttaaattt cctcctgtaa acgacgacta
    63661 tacttttcac tgatattgga aaggggcaag ataataaaca tcatacaagg aagagtgatg
    63721 aataaaagta gagaaagatt ccaatcaaga ctaaataaga ctacaatgga accaagtacc
    63781 ataactaaac tcagaataat atttgggaaa gtcgtaatta aaaactcacg aatgacactc
    63841 atgtcattga caatggcaga agtcaactcc ccactttggc tcttatcaaa gaaggatttc
    63901 tctgcataaa tcaacccctc tatcactttt ttcctgattt ttgctatctt tttttcaccc
    63961 gattgactaa acagatagta accaatagaa gaaaacaagg cttgaccaat aaaaatcaaa
    64021 aacgattgaa atactttgga acctatattt tcaatagaac tcccatctat taaacccttt
    64081 aagataaggg gaagcaacaa agcaagtaga ctagacagaa caagtaagaa actccccata
    64141 atcaccttag tatctactct taataatttt aatttcataa atactcctta taatatttca
    64201 acggataaag tcgggaataa ctcaatttga ggataaaatc taataaatct tcctataaca
    64261 aaacgcataa catctaggat tttatatacc tgatattatg cgtttttaag cacaaagact
    64321 tcttacacaa acttatctac aattagattt tatttgacat gttttgccaa ttcttcttgg
    64381 gcttttttat tggattcttc tttttctttc aaccattttt ctctggcttt tgcatattcg
    64441 tctgttgtga caatcttatc ttgtactttg aggtatttat atgattcaac cccttttgta
    64501 ccggttaaac cataggcagc agcaaatggt acggttcttc tcaatgatgg tgttccccca
    64561 cgcgaaacac ttggaagaac taaagaacta tcaatcaacc aagcttgaat atcagcatat
    64621 ttctcataac gtttggctgg atcttgctct ttattagctt cttccaacat ttgagtatag
    64681 acatccagtc caactgcctt agccttgtca ttggcttctc caggctctag tccaagattt
    64741 tgtagaactc ctccactatt agtattaaaa atatcgagat aggttgacgg gtcttgataa
    64801 tcaggtcccc aaccgccatg atataaatca tagtctttct gagcagctgt ttgagcaaag
    64861 tagcctgaac tgtcaaactc atctgatgtt aattgctgaa tgtcaatcac tacattatca
    64921 gaacctaaaa cagattcaat tgattgtttg atagaactaa ctccttgtat gcctacttta
    64981 tctgttactt ccacagtctt atccaagtgg attgggaatt gaacaccctt tgcttcgagt
    65041 tctttcttag cttccgcaaa cttagccttg gctttctcag gattgtagta agggtcttga
    65101 ccatccgcaa agttgatacc ttgccattcc ttaccatagt tgaccatctt agaggctaca
    65161 acttcaccaa agtcttttcc cttgatactg acaaagtttg gaggaaccac taggttacgc
    65221 aaaatctttg ttgcaccttc tttcccttca gactgagccc cataagatgt tctgtcaaaa
    65281 gcaaaattga tagcctgacg gaagttttta ttgagaactg cttcctgagt cgatttcttt
    65341 tcaatgtcac ttgttttaga agtataattg taagacttcc tatctaggtt aaaattaaag
    65401 aaatatgaag ttgaattttg catactatag atgatattgt ttttgtattt ttctttaatc
    65461 ccttcatagc tggagctgtt aggaaaaaga cgagccgtag tataagcacc agctgtaaaa
    65521 ttacgttcca gtgattcttg gtcgctacca tcatagtagg tcaatttcac atcgtctaca
    65581 aagacattct tagcatccca gtaattaggg tttttcttat attcaatagc agattttgag
    65641 acaagtgctt tcatcaagaa aggtccattg tacaaaatac tagatggatc cgccttccca
    65701 aaatcatccc cttttgattt caggaaatct gcattaacag gaaaaagtat cgttgcaagt
    65761 gtttttgaat tccagtaaag ttctggttta accaaagtat attgaaccgt ttggtcatca
    65821 agtgccttga caccgacagt tgaaaagtcg cttgttttac cagtgatata gtcatccaaa
    65881 ccagcaacag agtcctgcac tagatacaag gcttctgatt ttttatcagc tgcatattgc
    65941 aaacctgtca caaaatcctg ggcagttaca ggcgcatatt cttctccctc agaagtaaac
    66001 cacttggcat ccttacgaag tttgtaggta taggtcaaac cgtcctgaga aacagtccaa
    66061 tcctctgcta atgatggaat aatattccca tattggtcat tttctaataa cccgtctacc
    66121 aaatttgcaa caatatcgga tgttgctgcg cggttttctg ctagatagtt caagctagat
    66181 ggatcacttg aataaacata gttgtaggtt tttgacgccg tgctagaatt tccacacgcg
    66241 ctcaataaaa ctcctgtacc caggacaaga cctgccaagg ttagatattt gctcttagac
    66301 tttttcattt ccagaacctc ctgctttaaa tatttgtttt attatacaac tcttggtttg
    66361 tttagtcaat tgttttttcc aaaaaatcaa aaaaacctca ttttatattt ttgaaagata
    66421 attttagcta ttttgacgct aaaaaaggaa taagtttcaa gttctcctaa aagattgttc
    66481 aacttattcc ttttatttat aaatgctacc ttacgaaagc ttaaattttg ctcgcaggcg
    66541 atctgcttgg gcttttccta ttaccttatc taataaatag gtacgcagac tcataaccat
    66601 ataaagtcca ccccccatgg caccgacaag agctacataa aagaagctcc acaaacgtcc
    66661 acttggttgg aagaaaaatc ctaacagcca ctggatggtt cctattaaca gaaacatgac
    66721 tagggtcagc aaactgatta aaatggttcg cttcaaaatc accttgcgct tgacaccagt
    66781 tactttacaa atatcccgat acatcaagac gttaggaatg atgagagcaa tggttgttga
    66841 aatcaaagga ccataactgt ggaagagggc gatggtaggt agttgcaaga ctagcttggc
    66901 aatagaacca tagataaaat agagaacggc cttgcggttg cggaacatgg cctgaagcat
    66961 tggagacaag accatgtaca agcctaaaat aatagactgc aaaactgcaa agacaaataa
    67021 gcccagagcc aaactatctg gcttaccata gaagaccgta taaagaggtt ctcctaccat
    67081 aaccactcca accgttgctg gtagcaagaa cataaagagt agggtgagac tgtcctgaac
    67141 gagacgagaa gccgctttca agtccccctt gacatagttt tccgtcaaaa gtggcaaacc
    67201 aacactccca atcgaaaccc ctacagaaat caaaatcatc gtgattttat taggattggc
    67261 tgagaaataa gaaaacatga caaccaagtc ctcattgctg tagttggtaa accagctcat
    67321 actattgata aaggtcagct gatccaaaat ctggaagagc tggatggcag accctgtcag
    67381 gataaaagga atggcttcct taatggtatc aaccaagaga cgcttactgt taatcttatc
    67441 tcctgtttca aagactcttt tgagtgaacc ttcttgggca aggaaataaa tcaagactgc
    67501 aaaactggct accataccga caaaggcagc aaaggttgat tgggtaacgg ctgctagata
    67561 atctcctgaa ccgagcttca taatgataaa ggttgctagg agcatccaga taacacgaat
    67621 gacctgctca gcaatttggc tcatggcata gggtttgagg ttattcatcc cttggaaaaa
    67681 tcctcggata acactcatag acgggaaaat caagactccc caagccaagc tttgcatgat
    67741 tgggatcaag tctttgccca cgccagacaa gtctgctagc caaggagcaa agacatacaa
    67801 gactaaagca aaaaccaggc ctagtcctgt cataaagcct aagaagctcc gaatcagggc
    67861 aaagctatgc tcttcttctc gcatggtatt atacttggca acttgcttgg ccaccgcaac
    67921 tggaatcccc gctgttgaaa ccaacaagaa ccaagcatag atattgtaac ccatggtaaa
    67981 gagaccattt gccttagctg cataagcccc catccagatg taccaaggga taatgtaaac
    68041 agccccgagt aggcgactga taaagttact agccgttagc caagcagtcc cccgtaacat
    68101 ctgggcctgc tggtgattgt tttcgtgcga catagattcc tcattcaatt ttgataacta
    68161 ggaaaaactc cttatcttcc attataaact tttccttgtt acttgtaaat ttacgacttt
    68221 cggtttacaa tagaaagtat gattaagatt gaaaccgtat tagatatttt aaagaaagat
    68281 ggcctttttc gcgaaattat tgaccaaggt cattaccact acaactacag caaagttgtt
    68341 tttgatagca tcagctacga tagccgaaaa gtaacagaag acactctttt ttttgcaaaa
    68401 ggcgctgcct ttaaaaaaga ataccttctt tctgctataa cacaaggatt agcttggtat
    68461 gtagctgaaa aggactacga agtcggtatc cctgtcatca ttgtgaacga tataaagaaa
    68521 gccatgagtt tgattgccat ggagttctat ggtaatccac aggaaaaact caaactcctt
    68581 gcctttactg gtactaaggg taagacaaca gcagcctatt tcgcctataa catcttatct
    68641 caagggcata gacctgctat gttgtcgacc atgaacacaa ctcttgatgg cgagactttc
    68701 tttaagtcag cgttgacaac ccctgagagt attgacctct ttgacatgat gaatcaggct
    68761 gtgcaaaatg accgtaccca cctcatcatg gaagtctcca gtcaagccta tctggtcaaa
    68821 cgtgtctatg gtctaacctt tgatgtggga gttttcctaa atatcagccc agaccatatc
    68881 ggcccgattg aacaccctag ctttgaagac tatttctacc acaagcgtct cttgatggaa
    68941 aatagccgag cagtcatcat taacagtgac atggaccact tctcagtctt gagagaacag
    69001 gttgaagatc aagaccatga tttctatggt agccaatttg ataaccaaat cgagaattcc
    69061 aaagccttta gcttttcagc tacaggtaaa ctcgctggag attatgatat ccaactcatt
    69121 ggcaacttca accaagaaaa tgcagttgct gctggacttg cttgtctccg tctcggagca
    69181 agtcttgagg acatcaaaaa aggcatcgct gcaacccgcg ttcctggtcg tatggaagtc
    69241 ctcactcaga aaaatggagc caaggtcttc atcgactatg cccacaatgg ggatagtctg
    69301 aaaaaactca tcaatgtggt ggaaactcat caaaccggaa agattgctct ggttctggga
    69361 tcaacaggaa acaagggaga aagtcgtcgt aaggactttg gcctcctcct caatcaacag
    69421 cctgagattc aagtctttct gactgctgat gaccctaact atgaagaccc aatggccatt
    69481 gcagatgaaa ttagtagcta catcaatcat cctgttgaaa agattgcgga tcgccaagaa
    69541 gccatcaagg cggcaatggc tatcacaaat catgaattag atgcagttat tattgcgggt
    69601 aagggagccg attgttacca aatcatccag ggcaagaaag aatcctaccc aggagataca
    69661 gccgtcgcag aaaattattt ataagaatag aaaaaatcaa gggaaaatga aacccttgat
    69721 tttttcctat tatttagtaa aaacgttttt caaaccttct acagcacctt ttgcgtcttc
    69781 tacaacgtct tttgccttag caactgtttt ttcaacagct ccttcaagtt ctgtcttgct
    69841 gtctccagta actttaccaa aaccttcttt gacagcgcct gttgcttgtt ccaatttgtt
    69901 ttcaagtgac atatgattgt ctcctttagt ttattccgat atgtgttacc ggttacatat
    69961 agtttatacc gaatactaag gaaagtcaaa caatgtgctc agaaacaaga aatcacgcta
    70021 agtagaaagt taatctctcc ttatcaaaat cgatagccaa ctcatacttt ctatcttcat
    70081 tttgcacaat atagcctaag acaaccaaac tgtccacaaa gatatcacgg catttctgca
    70141 taagctggtc ttttttgaga aatttcaaca aaaaagccgt catatacttg agggcatact
    70201 caggattaac atctcctaaa atgtcataga gctcctgctg tttttctgtc aaaggatact
    70261 gctgtttgac cttgtaaaaa taattggaca gggtcatttt aatgcgcgca aagtccgtct
    70321 ttcaactaaa atagctgcat tgatttgatt gcgcaattcc gtctcaaaac tctgctccaa
    70381 caaggcttga tagaccggac tagcttctct gacaaaaatc tcttgatcca gttcaagact
    70441 atcaagtgat tcaagcgtag gaaaattgag gtaatagcgc ttattttcac gtagaatcaa
    70501 gcctgccttt atatactctt ccatgagttt atcaactgca acatctggaa attgagcctt
    70561 aatttcccgt agaatcacat cctcatactg gtccagatag cggatcaatt ctccaaaaat
    70621 ggctgtctcg tcaaacgaga tggattaaaa atctgaatca tgaagattcc tttctttaca
    70681 ttgtaacaga ggcgatgctg ccaactgact aggattggtc ccagcttggt tcagaggaac
    70741 aggcagacct agttctatgt aatactccct ccaaaaatca ctaatctcct gttccccatc
    70801 tccaaatttc ataggaatag tttcaaaaat aggtaggatt tctgctatat actgggagca
    70861 gtagaaacca gctgcatctg gatagaaaga agcattgtag ggtgctccaa gatgtctgca
    70921 agctctttcc ttcaccgact ggatatccat ttctgggtaa acatagaggt cgtataaatg
    70981 attggactca aagaagtctg ccggttcttg acagacaaca ccagcctgtc cactagcatg
    71041 ataaatcatc ccatccaaat aaatggcaac atggctatag ttacctgtgg aagtctggat
    71101 ggcctgtccc atgtctgacc catctctcac aaaaatcaaa tcgccatttt ctaacatact
    71161 tcactcctag aaaaaaagga gccgaaactc ctttcgatat aaggcaaact agactttccg
    71221 attttgagct gacacccaaa atcttacgca ttaaagcttt cagttaattg aggtaccact
    71281 tgtttcttac gtgaaacggc accagcaagg aaggcatgat tgttttcaag tttgaaattg
    71341 aaagccgctt cgaccttgtc catattggca ccaagagcca atatttctga gtttgagttg
    71401 acgatatctg taatcatcaa gacaaagtca gagtagccgt ttgattcgtt ggcagcttgc
    71461 attgcagctt caatttctgc ttggcgttcc aaaacttcag cgatgtcaac tgtgttcact
    71521 tgggcaacac ggacattatt tccgttgagt tcaaaagtct tagcatcgat gtcaatcaat
    71581 tcttcagcag atttgctagc caagttggta ccagctttca acattgccaa accatattct
    71641 tccaagttta caccagccaa ttcagccaat tcaggagcaa tgattttatc tgttgggtgt
    71701 gttgttggtg atttcaaaag aagggtatct gaaatcaaac ctgaaagcat caaacctgca
    71761 atctctttag gcacagctac accatgttct ttgaacatac ggtaaacgat tgaagacgct
    71821 gatccaactg gctccaaacg catgtaaagt gggcttgcag tttcaaagtt agccacacgg
    71881 tggtggtcta caacaccgta aacttctact tcagcgatat ctgatacaga ttgttggaat
    71941 tcattgtggt cagtcaagat aacttgctct gccccctctg ctttggcaga agtgataaca
    72001 cgtggtgctt ccacaccaaa atagttcaag acaaaggctg tttcttcatt tggagttcca
    72061 agggcaacag cttccgtatc caaaccgtaa gcttcttttg caaggtaggc aaaagctaca
    72121 gatgatccga tggcatctga gtctggattt tggtgaccaa atactagaat cttggacatg
    72181 ataatacctc attttgttta ttttctttat tgtagcattt ttttcgcttt ttgacaaagg
    72241 taagaggagt caaaggactc cccacgattc ttcaaaataa ctgagtaaat ttctatcttg
    72301 attttcagat aaaaattctt ccttctgtgg cctcttctta cgcttgagaa gagcttcagc
    72361 cgacatggct tcttccttac tggcaaaacc ttgagcatag ataagtttga ctggcaagcg
    72421 tgctcgtgta tatttggctc ccttcccact attgtggata gcgaggcgtc ttctcatatc
    72481 agtcgtatag cctatatagt aggatccatc acgacactcc agaacgtaca tataagcctt
    72541 atgatccata ataaatctct tcgatttcgg gcgtataaga gccatcatca ttgtggacaa
    72601 tcaaaggagg taagacctta aagccacttg ttgagccatc cttgatcgcc tcaatcaaaa
    72661 gcatattggc ttccttttct ctttttggat aaacaaactg caggcgctta ggggctagat
    72721 tatgtcgttt taacgtatcc aaaatatcca gaagtcgatc aggacgatga accatggcca
    72781 aacgcccatt agacttgaga atactctggg cactacgaca gatttcttcc aaattagtcg
    72841 tgatttcgtg tcgagccaag agataatgtt cactctcgtt cagattagaa taaggattca
    72901 ccttgaaata gggtggatta cacaaaatca tatccacctt actcccctga atgtgagcag
    72961 gcatattttt caaatcatcg cagatgacct gcatttgctc ctctaatcca ttcaaacgga
    73021 cagagcgttc agccatatcc gccaaacgct cctgaatctc aacagacaat atctgtgctt
    73081 gagtacgagt gctagcaaaa agccccactg ctccattccc agcacagaaa tccacaatca
    73141 accccttctt aggaaaacgt ggaaatcgtg ataagagaac actatccacc gaatagctaa
    73201 aaacctctct attttgaatg attttgatat ctgtcgaaaa gagctggtta atgcgctctc
    73261 ctgattttaa taattgttct tcttccatgg tcctattata gcaaattcat attaacatta
    73321 caaaaaatat aaaactctaa actacttctt cttttttaaa tggtgcaggg cttctccagt
    73381 ccagattggt agcattcgtc gaaagggagc aaaaccgtag ttaaagcggt cgcttgaaaa
    73441 gcgtctccgt ctaggaaact ggtacttttc ttcctccaaa gtgcggatag aaagactggc
    73501 tttccccgta aattcatcta aatccactac ctgaacttga acctcttcat cgactttcaa
    73561 ggtttcgtga atattttcaa taaatcctgt ccgaatttct gaaatgtgaa tcagccccgt
    73621 atcacccgtc tctaactcaa caaaggcacc gtagggctga atccctgtaa tacgcccctt
    73681 tagcttatca ccgattttca tcttagtcct cgatttcaat agtttcaatt acaacatctt
    73741 caactggctt gtccatagct cctgtctcaa cagcagcaat gacatccaag acagcgtaag
    73801 atgcttcatc agctaactga ccaaaaaccg tgtgacggcg gtctaggtga ggtgtcccac
    73861 cttgattggc atagatttct gcaatcggtt ctggccaacc accacgagta atttctttct
    73921 tagaataagg taggtgttgg ttttgcacga taaagaactg gctgccgttg gtatttggac
    73981 cagcatttgc catggaaaga gcaccacgga tattgtaaag ctcttctgag aattcatcct
    74041 caaaagattc gccgtagatt gactcgccac ccataccagt tccagttggg tctccacctt
    74101 ggatcataaa gtccttgata atacggtgga aaatgacacc atcatagtag ccatcttttg
    74161 aaagagatac aaagttagcc actgttttag gagcatgttc agggaaaagc ttgatacgta
    74221 agtctccgtg attggtctta atagtcgcaa gaggaccttc tactgtttca atgtctactt
    74281 gtggaaaatg caattctttt tctaccatac caaatacttc taaggcatca aaaatgccat
    74341 cttcttctaa tgtttttgta atataatctg ctttttcttt gattttatca tgagaaattc
    74401 ccatggcaac gctgattcca gcataatcaa agagttccaa gtcgttgaga ccatctccaa
    74461 aaaccatgac cttctctggt ttcaagccaa ggtgttccac aaccttttcc acccccgtcg
    74521 ctttggagcc tgaaatcggc acaatatcag acgaatgttg atgccaacga accatgcgaa
    74581 gtttgtctga gagactgtca ggcaagtgca agtcatctcc cttatcttca aaagtccaca
    74641 tctgatagat atcttctttt tcatggaaat cgggatctac atctaagtcg ggataaattg
    74701 gattgatagc ttcactcatc atatcggtgc gagtcgacaa cttggcatca tgactcccaa
    74761 ccaagccata ctcaattcct tcttgcttag cccaagagat atactcctca acatatgact
    74821 tttcaatctg atgctgataa atgacctgac cttttttatc ttcgatataa gccccattca
    74881 aagttacaaa aaagtcaggc ttgagatcac gaatctctgg aacaacacca aaaatgccac
    74941 gtccagaggc gattcctgtt aaaattcctt tttcacgcaa ctgtttaaaa acagtgggaa
    75001 ttgtagttgg aataaaccct gtctttgaat tccgcaatgt atcatcaata tcaaaaaaga
    75061 caatcttgat cttctttgcc ttgtatctta atttcgcgtc catctcacta cctctttcaa
    75121 tctaactctt tccattatat cataaagtag gcaaatcccc tattttcaaa aagtttatca
    75181 tttttatttt aatttcttgg atgagaaaaa agacatattt atgaaaaagc tccatcgtgc
    75241 ttttaatgtg ttctcttgtt ttcaaactcg taaaaaggga gccactgagc ctaactcgct
    75301 ctctcatttc aaagcttgtg aaaaaagacc cgttggggtc ttaattcgct ttcttgtttt
    75361 caagctcatg aaaaagagac ccaaccgggt cttttcttta atcttcgttt acgaaaggca
    75421 tcaaagccat tacgcgagcg cgtttgatag ctgttgttac tttacgttgg tttttagctg
    75481 aagttcctgt tacacgacga ggaaggattt tcccacgttc tgaaacgaaa cggctaagaa
    75541 gctcagtatc tttgtaatca acatattcaa ttttgtttgc tgcgatgtaa tcaacttttt
    75601 tacggcgttt gaatccgcca cgacgttgtt gagccatgtt ttttctcctt tataagttta
    75661 gttgtccatt agaatggtaa atcatcatct gaaatatcca atgggtttgt tgctccaaat
    75721 ggattttcat tacgtgaaaa gtctggtact gaatttgtag gtgctgaata gtttgcagtt
    75781 ggtgcagagt aagctccacc tgtgtggccc tcacgcacac tacggctttc caacatttgg
    75841 aaattctcag ccacgacctc tgtcacgtag acacgttgtc cttgctggtt atcgtaacta
    75901 cgagtctgga tacgacctgt caccccgata agtgagcctt ttttagccca gttagcaaga
    75961 ttttcagcct gttggcgcca cataacgaca ttgataaaat cagcctcacg ttcaccattt
    76021 tgactcttaa atgtacggtt tactgcaaga gtaaaagtcg caactgctac atttgatggg
    76081 gtataacgca actcagcgtc acgtgtcata cgccctacaa gtacaacatt gttaatcata
    76141 gtttaccttc ttacgcgtca attttgacga tcatgtgacg aagaatgtca gcgttgattt
    76201 ttgaaagacg gtcaaactct ttaagagctg catcgtcatt tgcttcaacg ttaacgatgt
    76261 ggtaaagtcc ttcacggaaa tcttggattt cgtatgcaag acgacgtttt tcccaagttt
    76321 ttgattcaac aacagttgca ccgttgtcag tcaaaataga gtcaaaacgt gctaccaaag
    76381 cgtttttagc ttcttcttca atgtttggac gaatgatata aagaatttcg tatttagcca
    76441 ttgatatgtt cctccttttg gtctaatgac cccaagactt tgcaaggggt aagtgaggtt
    76501 cgctcacaat aaactattat actagaaaaa atttttttac gcaagtaaaa acactagaat
    76561 tcgaaaaaac gccacatggg cgttttcctg ttcttatggt ttgatacggt gcaacatacg
    76621 tgggaatgga atagcttcac ggatatgttt tgttcctgct gcgaaggtta ccatacgttc
    76681 gataccgata ccaaatcctc cgtgtggaac tgtaccgtat ttacgaaggt caaggtagaa
    76741 ttcatattct gtacgatcca tgccaagttc atccatctta gcgacaaggg catcgtaatc
    76801 ttcctcacgc atagacccac cgataatttc tccatagcct tctggagcaa gcaagtctgc
    76861 acaaagcacg cgctctggat ttccaggaac tggtttcatg tagaaggcct tgatggctgc
    76921 tggatagttc atgacaaatg ttggcacacc aaagtggttt gaaatccaag tttcgtgtgg
    76981 tgacccaaag tcatcaccat gctcaagatg ctcgtagtca gcatcttcat cattttcatg
    77041 ctcttgcaag aggtcaatgg cttgatcgta agtgatacgt ttgaatggct ctgcaatgta
    77101 gcgtttcaag agttctgtat cacgttccaa ggtttccaag gcttgaggcg cgcggtcaag
    77161 aacaccttgt agaagagctt tcacataagc ttcttgcaag tcaagcgact catcatgtgt
    77221 caagtatgag tactcagcat ccatcatcca gaactcagtc aagtgacggc gtgtttttga
    77281 tttttcagca cggaaaactg gaccaaagtc aaagacacga ccaagagcca tagcccctgc
    77341 ttctaggtaa agctgacctg attggctcaa gtaggctggc gttccgaagt agtcagtttc
    77401 aaagagttct gtagaatctt ctgccgcatt tcctgaaaga attgggctgt caaacttcat
    77461 aaaaccgttc ttgtcaaaga actcataagt tgcatagata atagcgttac ggatttgcaa
    77521 cacagctact tgcttacgag agcgtagcca caagtgacgg ttatccatca aaaagtctgt
    77581 tccgtgttct tttggtgtga ttgggtagtc ttgagattca ccgatcactt cgatgtctgt
    77641 gatgtccaac tcatagccaa atttagaacg ttcgtcctct ttgacaatac ctgtcacata
    77701 aacagacgtt tcttggctca agcgtttgat aacatcaaac ttctcaagtc ccacttcttc
    77761 accaaatttt tcgacaaagt ttggtttaaa agccacacct tgaaagaagg ctgttccatc
    77821 acgcaattgt aagaaagcga tttttccttt tcctgatttg ttggcaaccc aagcgccaat
    77881 cgtcacttcc tgaccaacat agtcttttac gtcaataatc gttacacgtt ttgtcattat
    77941 ttttcctttt cttttttatt ctttatggca aaccacctct atattgttcc catccaggtc
    78001 aatcataaaa gcagcatagt aaatcggatg ctcacttcga taaccaggaa ccccattgtc
    78061 tcgcccacct gcctctatgc cagcctcata acaagcctga acttcttcct tattttctgc
    78121 taaaaaagca aaatgaacag gatcttgtgt tccctgagtc agccaaaaat caccaccagg
    78181 atgagggctg ttcggggata gaaaactaat tagagaacta gtcttaaaag ccaatttata
    78241 gtccaaagga gcgagaaaac tcctataaaa tccttctgaa atttgtaaat cctttacctt
    78301 aatctcaaaa tgatcaatca ttctcactac ccataaatgc tttcaagcgt tcgactgctt
    78361 ctttaagcgt gtctaggtct gtcgcatagc tgaggcggac attttctggt gctccaaatc
    78421 cagctcctgt taccaaggcc acttcggctt cttctaatat agcagttgta aagtctgtca
    78481 catccgtgta gcctttcatc tccatggcct ttttgacatt tgggaataga tagaaagccc
    78541 cttgtggttt gaccacttca aatcctggca cctctgcaag gaggggatag atggtattaa
    78601 gacgtttctc aaaggcctga cgcatgcttt ctacagtatc ttgctcacct gatagagcct
    78661 caactgctgc atattgggct actgctgacg gattcgaagt tgtttgacct gcaatcttgg
    78721 acatggcagc gataatgtct gcttctccaa cggcataacc aatccgccaa ccagtcatgg
    78781 cataggtttt agacacacca ttgatgacca ctgtttgctt gcgaatcgct tccgataggc
    78841 tagaaatcgg tgtgaactca tgaccattat aaaccaagcg gccatagata tcatctgcta
    78901 ggatgagaat atcattttct acagcccagt ttccaattgc caagagttcc tcacgggtgt
    78961 aaatcatacc tgtgggatta gatggcgaat tcagcaccaa aaccttggtc ttgtcagtgc
    79021 gagctgcttc taactgctct acggtcacct taaagtgatt gtcttcctta gcagaaacaa
    79081 agacgggaac gccttctgcc atcttgacct gatctccata gctaacccag tatggggttg
    79141 ggatgatgac ttcatcacct ggattgacca cagccataaa gaaggtatag agagaatatt
    79201 tggctcccgc agcgactgtc acttgatttg gcgctacaga atagccgtaa aagcgctcaa
    79261 agtagctatt gaccaccgcc ttaagctctg gcagacctga ggttactgta taaaaagaag
    79321 cacgcccatc tcgaatcgat gcaatggcgg catcttggat atttttggga gtagtgaaat
    79381 ctggctcacc caaggttaga gacaaaatat ctctgccctc agccttcagt gctttggcac
    79441 gggctccagc agccaaagtc acactttctt ccatttctaa aacacggttg gataatttca
    79501 taggccctcc ttgttgacca atgctcctgt ttcaaaatct actagataaa aatcagatcc
    79561 tgacttgact tcccagattg gcttatcttg ataacgacca aagataatct tgtcaatttc
    79621 gccagctccc ttttccttag aaaccgtttc tgctttttct tgtgaaacac cctgatttag
    79681 ctgataaacg taaatcttat gatcatcttt tccaatcaga acagcaagtg cttcttgctg
    79741 tttattacga ccaagaacgc tgtaataaga ttccaagcca ttgtataaat caacctgatc
    79801 ggcctgctct aatcctgcat actgctgagc taatttttct ccttcacttt tagctgtttg
    79861 atagggtttc atgctaagag aaaccatata cagaaaggaa gcactgataa ccacaaacaa
    79921 aatcgtcatc cctagaccat actgccacag tagattattt tttgctttgt tttgtctttt
    79981 tttcactcgt ctattttacc atctattaag ctttattaca agtgaatata agaatactct
    80041 tcgaaaatct cttcaaacca cgtcagcttt atctgcaacc tcaaagctgt gctttgagca
    80101 accaattcta tttctccctt caaacaaaac cgattttgaa agtgaaacag ttcttacttt
    80161 ttcagtcaca agtgactaga gtttcagcaa ttttataatt ttcaaataaa ctctgagcaa
    80221 atttcttgca agttgttttg ctttgttgta atatatttta taacaacgag aaaattctcg
    80281 taaatttaag aaaaaggaga cacatcatgt ctaaaaaagt attatttatc gtcggatcac
    80341 tacgccaagg ttctttcaac caccaaatgg ccctcgaagc tgagaaagca cttgctggta
    80401 aagcagaagt tagctacctt gattattcag cccttcctct cttcagccaa gatttggaag
    80461 ttccaactca tccagctgta gcggcagctc gtgaagctgt ccttgctgcg gatgccatct
    80521 ggatcttctc tccagtctac aacttctcta tccctggaac agtgaaaaac ttgcttgact
    80581 ggctatctcg tgcccttgac ttgtctgata cacgcggcgc ttctgccctt caagacaagt
    80641 tcgtcacagt atcatctgta gccaatgcag gtcacgatca actcttcgct atctacaaag
    80701 acctcttgcc atttatccgt acacaaggcg ttggtgattt cactgctgca cgtgttaatg
    80761 actctgcctg ggcagacgga aaattggttc ttgaagaaac agtcctaaac tcacttgaaa
    80821 aacaagctca agacttgatc gaagctatca agtaactaac actcaataaa aatcaaaaag
    80881 caaactagga agctagccgc aagctactca aagcactgct ttgaggttgt agatagaact
    80941 gacgaagtca gtaacatata tacggtaagg cgacactgac atggcttgaa gagattttcg
    81001 aagagtataa cataataaaa gcgaacaaga ctacttttct gacgctcaga agactagctt
    81061 gttcgctttt ttctcattta taaactaaaa tagctgatga tacatattgc caaatacaaa
    81121 atatctgatt tctatacttc ctttacaaaa accaatccct gtggttgtga caaatcttct
    81181 cggtaaacaa atccagcaaa gttcaagcga cgtgcttccc ccacagtttg tacttgattt
    81241 tctattaaag ctgttagaaa ggccccgcgc gctttcttgg agatagttga gtgaatcttc
    81301 agctgaccgc ctctatcctc catgaatttg aaggtcacca tctttgctct gatttcctta
    81361 gaaaatacag tctcaaactc tgatgacaag agagagaaaa tcacttcttc cttcttcaga
    81421 gcttcatcat agactgcctt ccaatggctc ttcaaagtct taccagcaac ttttaatttc
    81481 atcaaaaaat ccaaacggtg aggagccatg ggtgacaagg ctggaacaac accgtacaaa
    81541 gccgaggtaa tgaagacatg attttcaaga taatcttgtt ccgcctcggt cagcttatct
    81601 ctcttaatgt tgcggtacat aagcccatca aaaagtttca aggctggata gtgttgagta
    81661 gtttgccttt tcaaagcttg gatattttga aattcttccg ccgctttctc agctgatacc
    81721 ttgtagaaac tctccaattg actggcagaa tagagagcca aggcatcaag cacggcctga
    81781 ctttctggtt ttaaagaaat tgcctcgata cttggcaagt ctgtgttcat ttcttttgct
    81841 gttgggatta aaattttcat attgatagtg tagcatattt tttagccaca accaagaaat
    81901 tcatttgaaa aacctcggtt tgaccgaggt ttttctattt atttgggcca tcctaaccag
    81961 acagccacga gaacaagggc tgtgccagct aaacttgtta agatagataa gaatttatct
    82021 tttttctcct tgaactgaga aaaacctatc ttcaaagcga gcagtccgag tagcattgaa
    82081 gcaaccatca aataaaaacc catttctttg tcctccatta ggcttaattt accttattat
    82141 aacatatact ttctgaaaaa aacctatttt taccgtagct taaaggtctt gagataattg
    82201 tcttttccta cttgaccttc gaaggtttta ccattttcaa ggtaaggaag gtcatcggat
    82261 actgaagcct tgaccttgta tatcttgcca tcaactttaa agaagtagac agtgtctccc
    82321 ttgataacag ctgatttgag gtctgctact actccattga tgctttctgt cgttgcattg
    82381 tcaatttcaa ggtcgttttt attggcatac ttgctgagca tctcttccac tgtagtagca
    82441 acgataacat tttggtactc gactgcgtct accagggcgt actctttgac caagccagca
    82501 ttgtccttca agcccatgat gtagagaggc ttgtcattga ggttgatgag gattgggaag
    82561 gttgctttgt aggatttctc ctgaacagca ccttctgctg attcacgggc tgattcttct
    82621 gtcgcagaag ccaagctata cttagtgatt tctcctgttc gcatattttc aaggatgaaa
    82681 ccaagattac tctcatccgc attagccgac gtcacacctg tgtagagata gatgtcatta
    82741 ccgatagaca agtaattata gcccttggta gtctgggtca cgtttttctt ggaaatcatg
    82801 gcattcaaga aaccgtcctt gtacttgccg ttgtagttga tttgctcaat ggtttcctct
    82861 gctggataga tcctgtccac ccattctgga acatctgata agctgtattc cttggtttct
    82921 ccatttgtag catccaagat aatgactgaa gcaggacgag gaacagcaag tccaaattgc
    82981 ttttggtaaa ccgttgctac atagaaagga ttgccctcat cgtccacctc aaaagatgga
    83041 gttttaaaga ttttggtcgg gtacttcaag cgcaggtgac gtttgacatc acggttaaaa
    83101 tactccgagt ctgaatactt gattggtgtc ttcaagtcca ccaaatccgc atttccagtt
    83161 accatgtcca ccttgatata ctcaccgatt cccttggctt gattgttaaa ccatttgata
    83221 gggtctgcat attctagtgg tgtgacccga taaggtttcc catcaattgt caattgggta
    83281 taggtatctg ccgctacgta ttgcgacacc ttatcggtta gggaacccaa gtagcggtct
    83341 ccaatttttt cagcagtact tctatctagg ataggaacct tactggtgtc actcttagga
    83401 aattcagtaa agtctttttc cgtaaccgtg actacattgg cataattttt agcctgaaac
    83461 atgctggaag ttaccaagga aaccaaagct gccaagagaa gaattcctcc aatcgaagct
    83521 aacagaattt tccctaaccg attgattttg aaaccctcaa gatttaaggc agcttccgcc
    83581 ttaccgtggc gcacatgaac cgttttgaca aggtttatcc ccttgccaaa gccaaataag
    83641 attgccacaa ctaacaaatg cccacagagg aagaagagaa attcccagct ggtcaggtta
    83701 aggggcggta aaaagatata ccaggtcgtt gcgataaaaa taagttcaaa gactattcgt
    83761 ttcatttgct ttcctcctaa atgattcgtc cttccaagtg atccagctca tgctggcaaa
    83821 tctgagctgg gaagcctgtc aaggtaatgg tctgttcctg ccacttgctg tcacgatagg
    83881 caacccttat ggtttcataa cgcttagttg atctcacacc taccaaggac aaacagcctt
    83941 cttctgcctc ataggatcct tcaaaggaca gaagcactgg gttaaacatg accacgggaa
    84001 ccaagccaag attaaagata atcacgcgct tctgcacccc aatcatattg gcagctagac
    84061 caacacaggt atcacgattt gctaagagtg tatcctgcaa atctctggca agataaaggt
    84121 cctcctgact tgccggctga gacacttgag ataaaaataa gatatccttc acaattttct
    84181 tttccacttc ctcacactcc tcttgctttt tactatatta tagcaattat agcacaaaag
    84241 ccgataactg caaacccttt ccctcaactg tagcaaaaag ccatccgaag atgacttttt
    84301 tgctatttaa tttctgtata agttacttcc aagccacgct taacagctgg acgattggca
    84361 attttttctg cccattttac tagattttga taacttgagg catccaagaa ttttgcagaa
    84421 ccttggtaaa gatttccttg aactaactgt ccataccaag accagatagc aatatctgca
    84481 atcgtatagt cattgcctgc aatataaggt ttctgagcca attccttatc caataaatcc
    84541 aactggcgtt tcacttccat cgtaaaacgg ttaataggat attccaattt ttcaggagca
    84601 taattgaaga aatgtccaaa tcccccacct agaaaaggtg ctgcacctgc ttgccagaat
    84661 agccaattca aaacttctac cttttccaca ggattacttg gtaaaaaggc tccaaatttc
    84721 tcagcaaggt aaagaagaat atgagcagac tcaaagactc ttacgttttc agtacctgac
    84781 tggtccaata aggctggaat cttggaattt ggattgagct tcacaaagtc tgagccgaat
    84841 tgatccccat ccatgatagc aatcttatac aagtcgtaag ccgcttcctt aaaaccagct
    84901 tctagtaatt cttccaataa gatagtaacc ttcacaccat ttggtgttcc cagtgaataa
    84961 agctgaaaag cttgttctcc ttttggcaag ttttgttcga aacgggcacc tgctgttggt
    85021 ctgtttagcc ccgtaaaagc tccttgatta ctagcttcat cctgccatac ggtcggtaat
    85081 tgatatgctg acatccgaaa cctcccttaa atcgcattct tgtcaaaacc gagtttgcgt
    85141 tgaataaact taacgatttc gacgatgata atcattgaga agcttccagc cataacaatt
    85201 ccccattgtg acaagtctag tttggttacg tggaagattc cttcaagcgg ttctacaacg
    85261 attgttgcca tgagaaggat aaaggatacc aagatggacc agttaaaggt cttagacttg
    85321 aatgggccaa ctgtcaagat ggattggtag acagacttga cattgtaggc atggaagagc
    85381 tgaatcaaac caagggttgc aaaggccatc gttagggcat ctgcatgaat agcatgattg
    85441 tcacccacat gaactgggta agcaatcgca aggccataaa cactcataac aagagctgct
    85501 tggagtacac cttgataaat gatagaactc aaaacaccac ctgagaagaa gcttgccttg
    85561 cgtccacgtg gtttatgatt catgacacca ggttccgcag gttcaacacc tagtgcaatt
    85621 gctgggaagg tatccgttac caagttaatc cacaaaagat gaactggctg caagacgtcc
    85681 caaccaaaca aggttgatag gaagatggtt aatacttcag cagtattggc agaaagtagg
    85741 tactgaatag tcttttgaat atttgagaag accttacgtc cttcttccac tgcgacgata
    85801 atagtcgcaa agttatcatc tgcaagaatc atatcagaag cccccttaga aacctctgta
    85861 ccagtgattc ccataccgat accgatgtct gctgttttca gagctggggc atcattgaca
    85921 ccgtcacctg tcatggcaac gaccttacct tgtttttgcc aagccttgac gatacgaacc
    85981 ttgtgctctg gagacacacg ggcataaaca gagtattgac caacaacttt ttcaaagtct
    86041 tcatcagata attcgttgag ctcagcacca gttaaaacgt ggtcttctgt atcgtttgcg
    86101 tcaatgattc ccaaacgttt ggcaatagct tctgcggtgt cttggtggtc acctgtaatc
    86161 ataattggac gaattccagc ttccttagcc acacgaacag cctcagcagc ttcaggacgt
    86221 tcaggatcaa tcatcccaat caaaccagta aaaattaaat cattttcaag ctcttcagaa
    86281 gtgagatttt ctggaatact atcgataatc ttataagcac ctgcaaggac acgcaaggct
    86341 tgatgagcca tttcagaatt gtttgtatga atgagatttg taaccttctc atcaatcgga
    86401 gcaatatccc cagccttatc acgaagaaga caacgtttta agagttggtc tggcgcaccc
    86461 ttgactgcta caaggaaacg accatctggc aatgggtgaa ctgttgacat gagcttacgg
    86521 tcagagtcaa atggcaattc agctacacga ggatatttct ctaagaaacc tttgacatca
    86581 tagcccttgt ccaaggcata ttggataaag gctgtttcgg ttgggtcacc aatcaagtta
    86641 ccttccacat cgattttcgt atcattggcc aagacaactg aacgaagtag tggcatttca
    86701 agacctagtt caatatcatc agctgagtca tgtagaaccg catcgtagaa gactttttcg
    86761 actgtcatct tgttcatagt cagcgtacca gtcttatcag aagcgatgat ttcagttgaa
    86821 ccaagtgttt caactgctgg caacttacga acgatggaat gtcgtttggc caaaacttga
    86881 gtaccaagag aaagaacgat ggtaacgata gcaggaagtc cttctggaat ggctgcaaca
    86941 gcaagggcaa cagaagtcaa caactcacca agtggatttt tcccttgaat gaagacaccc
    87001 actacaaaag taacaagggc aatgaccaag atagcatagg tcaagacctt agaaaggttg
    87061 ttcaagtttt gtttgagtgg tgtatcagtc tcatccgcat cttgaagcat accagcaata
    87121 tgaccaactt cagtgtacat acctgtattg acaacaacac ccatcccacg accataggtt
    87181 acgtttgagt tttggaaggc catgttgaca cggtcaccaa taccagcatc tgtcgcaagc
    87241 tcgactgaca agtctttttc gactggtaca gattcacccg tcaaggctgc ttcttcaatt
    87301 ttaagagagt tggcttctag caaacgtagg tccgctggta ccacgtcacc tgcttcaagg
    87361 gcaacgatat cgcctggtac caattcttta gagtcaatct ctgccatgtg tccatcacga
    87421 agaacgcggg caactggact agacatggat ttgagggctt caatagcttc ttcagctttt
    87481 ccttcttggt aaacaccaaa ggcagcgttg atgataacca cagctaggat gataatggca
    87541 tctgcgatat cttccccacc agaagtcacg actgacaaga ttgctgccgc aactaggatg
    87601 ataatcatca aatccttaaa ttgctcgatg aatttgacca agattgatcg tttctcgcct
    87661 tcttcgagtt cattgtgccc aaattcggca aggcgctttt ccgcctcact tgatgacaaa
    87721 ccttgctcgg tcgcatccac agcctgcaag acctcttcag ggctctgagt ataaaacgct
    87781 tggcgttttt gttcttttga catgtgtctc ctccttgaca ttgtgtgcaa aacagactct
    87841 ctttctgtca tatcttttca cgacaaacaa aaagagacct gttaatcata acaagtctcg
    87901 ctgtttaaga tagggccgga aagcatactt ttcagcataa aattcggaat gacgacacta
    87961 tcacaggttt ctgccagcta ctcccttgag tagtaccatt ataccaaatt ttggggagtt
    88021 ttcaaagagt aaaaactgcc ttatttgaat ttttccttga aaaccagtat aatggtagaa
    88081 tgctatgtga ctagaaagga agttgaatga agcaatctat ctcaaatctc aagttagctg
    88141 agcgtggagc cattatcagt atttcgacct atttgatctt gtctgcagcc aaattagcag
    88201 ctggtcatct ccttcattca tccagtttgg tggccgatgg ttttaataac gtatcggaca
    88261 tcattggaaa tgtggccctc ttaatcggga ttcggatggc gcgccagcct gcagaccgtg
    88321 accaccgttt tggtcattgg aagattgaag atttggcaag cttgatcact tctatcatca
    88381 tgttctatgt cggtttcgat gttctaagag ataccattca aaagattctc agtcgggaag
    88441 aaacggtcat tgatcctctt ggtgcaactc taggaatcat ttctgcagcg attatgtttg
    88501 tggtctatct ctacaatact cgcctcagta agaaatccaa ctccaaggcg ctgaaggcag
    88561 ctgctaagga caatctttct gacgctgtta cctcacttgg aaccgccatt gccatcctag
    88621 ctagtagttt caattatccg attgtggata aactggttgc tatcatcatc actttcttta
    88681 tcttgaagac tgcctatgat atcttcatcg agtcttcctt tagtctttca gatggctttg
    88741 acgaccgcct gctcgaggac taccaaaagg ctatcatgga aattcccaaa atcagcaagg
    88801 tcaaatcgca aagaggtcgc acctacggta gcaacatcta cctggatatt acactagaga
    88861 tgaatcctga cttgtctgtt tttgaaagcc atgaaatcgc ggatcaggtc gagtctatgc
    88921 tggaggagcg ttttggcgtc tttgataccg atgtccatat cgaaccagca cctatccctg
    88981 aggatgaaat tttagacaat gtctataaaa aattgcttat gcgtgaacaa ttgatcgacc
    89041 aaggaaacca actagaagaa ctcttgactg atgattttgt ctatattcgc caagatggag
    89101 agcagatgga taaagaggct tataagacca aaaaagagtt aaattctgct atcaaggaca
    89161 ttcaaattac ttccatcagt caaaaaacca aacttatctg ctatgagtta gatggtatca
    89221 tccataccag tatctggcgt cgccacgaaa cctggcaaaa tatctttcat caagaaacca
    89281 aaaaagaata gagaaatcct ttcatgagac gggatttttc tattctttta tactcaataa
    89341 aaatcaaagt gcaaattagg aagccggtca caggctgtac ttgagtcggc aatgtgaagc
    89401 cgacatagtt tgcactttga ttttcgaata gtcttaacta tcaaattcac tgagatactc
    89461 atagcgttcg tatttttcaa ggagtgcttc atttttctca tccaattctt tttggagagt
    89521 agccagctta ccaaagtcag agccgttagc ctgcatttcc tcttcaatag cagcgatacg
    89581 tttttccaag gtttcaatat caccttcaat acttgcccac tcctgctttt cttggtaggt
    89641 catgcgtttc ttgtcttctc gaaccttgac cactttttcc ttttcggcct tttgcacttg
    89701 attggccata tctgtttcaa aagctttttc atcaagatag tcggtgtaat gaccaaagaa
    89761 aggacgaatc ttgccatcct caaaagcgag aatcttggtc gctaccttat ccaagaaata
    89821 gcggtcgtga ctgactgtta aaacgggacc tgcaaaacct tgcaagaaat tctccaagac
    89881 tgtcaaagtt gcaatatcta ggtcattggt tggctcgtct aaaagaagaa catttggttt
    89941 ttccaaaagc agtttgagga gataaagacg ttttttctca ccccctgaca atttctcaat
    90001 caaggttcca tgcgtcgaac gtgggaaaag gaactgctcc agcaactctg caatcgaagt
    90061 cgtagaaccg ccactggtct tgacctcttc tgccacttcc tgcaggtaat tgataactct
    90121 cttgctttca tccaaaccct caatttgctg agagaaatag gcgatgcgaa cagtttcccc
    90181 aatcacaact tgtcctttag ttggctcaag acttcctgca atcaagttga gcagggttga
    90241 ttttccaaca ccattgtccc caacgattcc gatacggtct ttggcctgca ccaagagatt
    90301 aaaatcttgc aaaataggct tgttttcata ggcaaaggaa acagcctgaa actcgatgac
    90361 tttcttccca atccgactgg tttcaaagtt catggtcaag tctgtctcag cactactgcc
    90421 tgaaacttcc tttttcagat catggaatcg attgatacgg gcctgctgct tggtcgcacg
    90481 cgcctgcggt tgtctgcgca tccaggccaa ttcttgtttg tagagttgtt cttttttgtg
    90541 aagaagagcc gcgtcgcgct catcctgttc cgcctttagg cgaacatagt cctggtaatt
    90601 tccctggtac tcggtcaagc ctgcacgatc caactcgaaa atccgtgttg acaaagcgtc
    90661 taagaaataa cgatcgtgag tgataaaaag gacggtcttc ttagaatttt tcaaaaagag
    90721 ggtcagccac tcaataatcg caatatccag atggttggtc ggctcatcca aaagcaagag
    90781 atcgtggttg ccaagtaaga cttgtgccaa ctgtacccgt cttctcagac cacctgacaa
    90841 ttccccaaca ggagtagata agtcttgaat gcccaatttg ctaagaacgg tcttgatctg
    90901 actttcgatt tcccaagctt ggagagagtc catctctgcc atgacacgtt ccaaacgcgc
    90961 ctgcttgtcc tcactatagt cgagcataat caattcatac tcacgaatga gctggatttc
    91021 cttgagttca ctagatagaa ccgtatccaa aactgtcttt ctatcatcaa aatcaggatc
    91081 ctgagtcaag taaccaatct ggtaatcatt tttagctgaa aaaggactga catccccatc
    91141 aaatccagaa acaccagaaa ggacgtccaa aagggtggtc ttgccagtcc cattgacacc
    91201 gattaaacca attctgtcta agtcatggat aataaaggaa atatccctaa aaacggtctt
    91261 gtcaccaacg gatttactta gtttttcaac gataaaatca ctcatttttt ctccctcagg
    91321 taagcatgga tggcttcacg attattctcc aattctccat cgacaatggc aaactcaatc
    91381 tctgttaaaa tctctcccaa gtctgggcct ggctgatagc catattcctt gatcaaaata
    91441 ccgccattaa tctgaatatc tttcttgtca tggatagtca agctttggta tttttctgtg
    91501 atggcttgtg ggttgacttc ttttccttga gcttgacgaa gattttcagc ctgtaaaagc
    91561 aaatctatgt caaagcgata acaatctcgc ttgctcaatt ctccattttc acgcagagcc
    91621 aaaataatca gcaaatcctg aacttgcttg gcaaactggc gtgaggtctt ccaagatttc
    91681 aaaaatgact gcgcattttc aatctccaaa gcccatagta aagccgccca ggcttgttca
    91741 gaggattcaa aagtaaaatc agtctccaaa tcaaacagtc tgttgagctt gtcctggcta
    91801 gatgccatat cagggagata gtcataagct tgactctcaa tcatggaagc caagcccctt
    91861 ctccaaaatg gagccagcaa gagtttatca aactcgacga aggtacgctc tacagaaatt
    91921 ttctccaaaa gcggcgtcaa ggtcttcata gctttaaatg tttctggctc aagtgcaaaa
    91981 ccaagactag cctgaaaacg gaaaccacgc ataatccgta aagcatcttc gttgaaacgc
    92041 tcactagcca ctccaactgc tcgcaagact tgcttttcca aatcttctaa accatggaac
    92101 aagtcaacga tttctcctgt ctcatccaag gcaaaggcgt tgactgtgaa atcacggcgt
    92161 ttgaggtctt cttctagcga gcgcacaaag gaaaccgcac tgggtctgcg atagtccaca
    92221 tagacatcct ctgtccgaaa ggttgttacc tcatactcct catccccatc taagaccaag
    92281 acggttccat gctcgattcc gatatcggct gttcgcggaa aaatctgctt ggtctcttct
    92341 ggataagaag acgtcgcaat atccacatcg tggatagggc tatggagaag ggcatctcga
    92401 acagagcccc caacaaaata agcctcaaag cctgcttctt taattttttc taatactggt
    92461 aaagccttct gaaattcaga aggcatttgc attaatctca taataagtgt tctaatccat
    92521 agacaagctc atgacgcttg acaacttctt taattcccaa attgactcct gtcatgaagg
    92581 agatgcgatc ataggagtca tgacggaggg tcaatccttc tccttgattg ccaaagatga
    92641 cttcctgatg ggctaccaaa cctggcaaac gaactgagtg gatgcgcata ccatcaaagt
    92701 cagcaccacg agcaccagta atcagctctt cctcatctgc tgcaccttgc tgaattgact
    92761 ctcgaatctc tgccatcaac tcagctgttt taatggctgt tccactcgga gcatcctttt
    92821 tcttgtcatg atggagctca ataatctcca catttgggaa atatttggca gcctgcgtcg
    92881 caaattgcat gagtaagaca gcacccaagg caaagttagg ggcaatcagg ccacccaagt
    92941 cttgggtacg agaaaattct tttagctctg caatttcttc actcgtgaaa ccagtcgttc
    93001 caactactgg agcaaagcca ttttcaagag caaaacgtgt attttcgtag gcaacagctg
    93061 gagtagtaaa atctacccag acatccgctt caaaacaagc taaatcagcc ttatccttga
    93121 aaacaggaat accctgccat tctgactcag actcaaaagg atccaaaact gctaccaagt
    93181 ccaagtctgg atcagtcaat accatctgac aagcagcctg gcccatcttt cccttaaaac
    93241 cggcaataat tactcgaata ctcatctcta ctcctgtcta agatacaaag tccgtaagaa
    93301 cacaaagtga aaataggaat tccaatcaag aagtgtctac ttcttggaag aactatcttt
    93361 ttcacacagg gttccaggcg tgttcaatta ttaagataca aaggacctta gctgcctctg
    93421 aaaaataggg aatggcactg actttccacg aaaggcaaga caggcatctt ttttcaagag
    93481 gcaggtagtc cgtgttcaat ttctaagata caaggcatct taactagcct agaagcgcca
    93541 actaaatcac tggaatataa cccagagcaa tacttcctgc tcctaggtgc gttccaatga
    93601 cactaccaaa tgtagcaagt gaaacatccg aacccaagcc aaaatcaagc aagtgctgac
    93661 gcaattcttc agccttttca ggagcattcc catgaatgac aatgacccgg tattgacctg
    93721 aagccgttgt ttccttgata atttcaatta agcgcttggt ggccttcttt tcagtacgaa
    93781 ctttttcgta aacttcaatc acaccttgat cgttaaaata aaggattggc ttaatgctaa
    93841 gcaaattgcc caaaatggca gccccatttg aaaggcgtcc accttttacc aaatgatcca
    93901 agtcatctac catgataaag gctgacgtac ggctgatttg aatggctagc ttatcctgaa
    93961 tgctggcaaa atcatcgccc tgatcacgcc aattaaagac gctttcaacc atgatgccta
    94021 ggggagcact tgtaatcaaa gtgtctggga aagcaatggt taagccctca tagtcatcga
    94081 ccatatactg gatattttgg taaaaacctg aaattccaga agataggaaa agccccaagg
    94141 catgtgtata gccttgttct ttgagcgaag ttaagatctc atctaacttg gcaatacttg
    94201 gttgactggt cttaggcaat tcagaagcct gagccatttt ttggtaaaat tcctcagcag
    94261 acagattgat gccttcgaca tattcctcac catcaatatt gacaggaata tccaagacaa
    94321 acaagtcttc tctttgcaag gtctcttcac tgagataagc agaggaatct gtgaaaacag
    94381 ctaatttcat attagaactc caaattaatt cctggtaagt ctaatgcaat ttcagtcact
    94441 tcgtaagtca aacgattgag catgttcaaa catggacgag ccaaggtttc cacctcttct
    94501 tggttcaatt cacttggttc attgacaata cggccatcga tatggtttac ttgtgagatt
    94561 gttccactaa tgacaaactt atcaaataca atcataaagc tcaagatgac aatcaaggaa
    94621 gtcacttgat tttcttggtc atgttggagc aattggaaat tcacatccac cttggtttca
    94681 ggagctccat tttcattttc ccattcaaaa ttacgcgcat caaaatgata ctgactaaca
    94741 aattcttgtt cacgtttaag attcatgtct ttctccatcg gctacaatat tataagctat
    94801 tgtaccataa ttttttattt tcatctagtt ttctaggatt tagtcaatcc caatttcagc
    94861 acgaactaca tctgtgatag tatcaacata gtagtccact tcttctgttg taggcgcttc
    94921 tgccataaca cgcaagaggg gctctgttcc acttggacga acaaggatac ggccgttccc
    94981 cgccatttct tcttccatct tctcgatgat ggccttgata gctggcactt ccatggcctt
    95041 ttccttcatg acgttttcca ctcggatatt aactaatttt tgtggataaa tcgttacttc
    95101 tgccgccaac tctgataagc ttttaccagt tttcttcata attttagtca attgaactgc
    95161 tgataattga ccatcacctg tggtattgta atccatcaag ataacgtgac cagactgttc
    95221 accaccaagg ttgtagcctg attttctcat ttcttcaaca acgtagcggt caccaactgc
    95281 agtaactgcc ttgttaatac cttcgcgatt caaggccttg tggaaaccaa ggttagacat
    95341 aacagttgtc acaattgtat tttgagccaa ttgtcctttt tcagaaaggt attttccgat
    95401 gatgtacata atcttgtcac catcgacgat gtcaccattc tcatcaacag caatcaagcg
    95461 gtcactgtct ccatcaaagg ccaaaccaat agctgaccca ctttctttga ccacttcttg
    95521 aagggcttct ggatgtgttg aaccaacatt aaggttgatg ttaagaccgt ctggtgtttc
    95581 cccgataacc gtcaattggg caccaaggtc tgcaaagatt tgacgggcac tggtagaagc
    95641 tgctccatta gctgtatcca aggcaacctt cattccatca agaggagttc cagttgaaac
    95701 aaggtatcct tcatacttac gcaagccttc tggataatct accaaaattc ctaagccttc
    95761 tgcacttgga cgaggaagag tgtcttcctc agcatctagc aaggcttcaa tttctgcttc
    95821 tttttcatca tctagtttga agccatcacc gccaaagaac ttgattccgt tatcaagggc
    95881 tgggttgtgg ctagcagaaa tcatgacacc ggcacttgct ccttcagttt caaccaagta
    95941 agctactgct ggtgttgcaa ggacaccaag tttgtatacg tgaatcccta ctgaaaggag
    96001 acctgccacc aaggccgatt ccagcatttc ccctgaaata cgtgtgtcac gtcctacaaa
    96061 gactttcggc gcttccgttt catgttgact aagaacatag cctccaaaac gtcctagttt
    96121 aaaggctaat tctggtgtta gttctaggtt agcttctcca cggactccat cagtcccaaa
    96181 atatttaccc attgttataa aatccttttc tatttttaat tcgtttttga actagttgct
    96241 ttcgttgacg aagatgtctc cgatgaactg cttgtacttg aatttgatgt gcttgaactt
    96301 ggtgctactg gttttgtagt caccttcatt attgtatcaa acggagtgat aactgccggt
    96361 aagacaacac cattgcggtc gattgcctgc aaaggtactg aaccactgta attacctgtt
    96421 atacgttcgc tagttggcaa gacagcgata atcttatcaa ttctatccaa tgtctcttgg
    96481 tcactcgtaa tcgacacttc tttatctgac accatgacat tttcaatttg tacccgacta
    96541 tcaatttgac tagggtcaat ctctggtaca atctttacct tatccttctg agccttctta
    96601 ccaatcttga ctgtaatttt ttgcggagtc gccacagcgg tcagcccatt gggtaaatct
    96661 tcaatgctca aaggaacttc aatcgttcca acaccggcat ctgttaggtc agcagtaacc
    96721 ttgaatttac gtgtactttc ttgcatttca ctagctagcg ataggcgatt tgcaccagtc
    96781 aagaccactg atacttctga agcaaaaccg ctaataaaat acttatcact attatagcgt
    96841 atgtcaatag ggacatttgt tactgtatta gtataggttt ccgtttttac ctgcctagca
    96901 ctggtactgt tttgaaaatt cgtcgccgta gcatagacaa ataagacaca agcaaaaaag
    96961 agtgaggata tgatatataa actatttttt ttcatgtttc catcctccta gccatcgttc
    97021 tttaaaacta agacccactt cctcttttgg aagtaagatt tcacgtaatt ctgtttcaaa
    97081 ttcatcaagt gttaggttgt gcttaaacct tccattatag gttatcgaaa ttcctcccgt
    97141 ttcctctgat acgacaaaag tcaaggcatc tgagacttct gataaaccga tagccgcccg
    97201 gtgtctggtc ccaaattcct tggaaatacc tgtgtttttt gtcaagggca gataggcaga
    97261 cgtcacagcg atacgttctt ctttgataat caccgcaccg tcatgtaggg gagtgttggg
    97321 aataaaaatg ttaatgagaa gttctgcaga aatcttagca tccaagggga ttcctgtcga
    97381 aatatactcc tgcaaggtac gtacacgctg aatagcaacc aaggccccga ttttacgagg
    97441 actcatgtat tcaacagact taacaaaggc acgaatcatc tgttcctcag cactaatagg
    97501 ggcattggaa aagaaatctg tcgctcttcc caaacgttcc aaaccagtcc gaatctctgg
    97561 agagaagata acaaccgccg caataacccc ataagtaata atttgattga ttaaccaaga
    97621 aatcgtagtc aaaccaatca tatttgcaag gatttgagct aaaataaata ccaaaactcc
    97681 acgtaccaaa atcataatct tggttcctgc aatagctttt gtaaaatggt ataaaatata
    97741 agcaacaatc aaaatatcaa tcagattgat agctatcgtc catggacttg caaacaaact
    97801 ggtccaatat tgcagattgg ataattgttg aaaattcatc cctgatatcc tccctatcaa
    97861 aacactttcg tcctattata ccattttcgg gcattttttt ccctatccta gtccatttta
    97921 cattgaacaa aaatatgata aaataaactg actagaaaaa acaaaggaga aactatgtct
    97981 caactctatg atattaccat tgtgggtggt ggtcctgtcg ggctttttgc agccttttat
    98041 gcccacctac gccaagccaa ggttcaaatc atcgactctc ttccccagct aggtggacaa
    98101 cctgctattc tctaccctga aaaggaaatc ctagacgtac caggcttccc aaacctgact
    98161 ggagaagagt tgactaaccg cttgattgaa cagctaaatg gatttgatac ccctattcat
    98221 ctcaatgaaa cggttcttga gattgacaaa caagaagaag aatttgccat cacaacttct
    98281 aaaggaagtc acctgactaa aacagttatc atcgctatgg gtggcggtgc cttcaaacca
    98341 cgtccgctgg aacttgaagg ggttgagggc tatgaaaata tccactacca cgtttctaac
    98401 attcagcaat acgctggtaa gaaagtgacg attcttggtg ggggagactc ggctgtggat
    98461 tgggctttgg cttttgaaaa aatcgcacca actacccttg ttcaccgcag agataatttc
    98521 cgtgccttgg aacacagtgt tcaagccttg caagaatcat ctgtaaccat caagacacca
    98581 ttcgcccctg gccaactcct tggaaatgga aaaacacttg ataaacttga aatcacaaaa
    98641 gtcaaatctg atgaaactga aaccattgac ctagaccacc tctttgtcaa ctatggtttc
    98701 aaatcttctg tcggtaacct taaaaactgg gggctcgacc tcaaccgtca caagattatc
    98761 gtcaacagca aacaagaatc cagccaagca ggtatctatg ctatcggtga ctgctgctac
    98821 tatgacggaa aaattgatct gattgcgaca ggcctcggag aagctccaac tgctgtcaac
    98881 aacgctatca actacattga ccctgaacaa aaagtacaac caaaacactc taccagttta
    98941 taaaaaagaa ccacgagtca cataggattc gtggttttat aattcatccg catttaaaaa
    99001 tacctttaca tcgttttact atatcttaca atacctttta aaacagctat attttgagct
    99061 tttaaataaa tgtttttaca tcattttaca gagatttacg acacttttgc cccttttttg
    99121 ccccttttga gcaaacaaaa aaaccgcaag cctgagcctg cggtgaaaga acaatttaga
    99181 aagtttcctt tctatttatt taactgtaat caagccatct ggctctactg tgaactctgg
    99241 cttgtctgcc atgctaccgt ctggtttgag gtagtaccag cctgttccgt ccgctgactg
    99301 gataaaggca tttgatacca tggcgccttc tttagcgtct aagtagtacc aggtgtcctt
    99361 gtacttgacc cagcctgtct tcatggcacc ttctacatca aaatagtacc acttctcagc
    99421 gattttcttc cagcctgtgg ccatttcgcc tgagttgtcg aaccagtacc aattaccgtc
    99481 tgtgtgcttc ttccagcggt ctgaaagcat atagcctgag ccatcgaaat aataccaggt
    99541 accgttgatt ttctcaaact tatcttttgg ataaaagccg tctgagtgta cgtaccagta
    99601 gccagtgcca tttttctgcc agcctgttgc agcgctcaag ccgttttcga tgtcttgctt
    99661 aaactgttca cggctaatgc cccaacttgc aagatatgga taagggtcaa cgtggtctga
    99721 gtggttgttt ggttggttat tggtacagta ttcatgcgtc ttgatacctg ccaagtcgtc
    99781 tgtatcaaga gtcttcggca agcctgcttc gtccgctaga ttgcgtagca attcgatata
    99841 gaggcgatag tcagccataa actcttcctt agttgaatgg ctttcaatca gttcaaccgc
    99901 tgcataggtc tcagcattcc aaccgccccc aacatcccaa cttccgttgt tcacaggtcc
    99961 tacctgcatg atgcgaccgt ttccgacaac gtgcgagaaa aaacctaatt ctgggtcttt
   100021 ccgccagtga taatccgctt cattctgtac ggttgagttg cggttacctg ttgagtgagc
   100081 atgtacttgt cgataaggct gcaccccaac ctgtggcaag cctgtacgta gtctgtttct
   100141 atcgatatcc attccctatc gtcctttcca tgcgtcattc atctgcttca ctgctgactc
   100201 tacgaaggtg tctaagtctt tgtcagtcat gctaatattg tattttgtaa gctcagcacg
   100261 gactttagcg cgagcctgtg ccagtttttc atctcccttg tagccagttt cagcagctac
   100321 ctgctccacg gcatttactg catttttagc tagaatttca gcgatgatca ccgctttctc
   100381 tccgccttta cgcaaaagat aatcttttac tgcttttaca ataccgccta ctgctactgt
   100441 taaaaagctt gtcgcaaaag caatgatgat ttcagtaatt tgctgcattt gttattctcc
   100501 ttttttcgtg tcatcatctt tttcaagtaa tcgctgaaat acttttacaa tcggctgaaa
   100561 aagagtaaca tttcctttta atttgcgata attttcaatg agagattgaa aagtaaatgc
   100621 gatgtacccg agatagattg agtgcaagaa tacaaaacct gtcttttcag gcaacaaaac
   100681 ggacgccgga atgaggatca tcagtaagag aacccctgaa atcttacgaa ggagcccgtt
   100741 aatgccgatt ttgctcttgt actcgatgtc aggattgata atcgccgcaa tcgtccctgt
   100801 cacaaaatca atgatttcca ttgagacaat cagtgctaga gcgtacaaaa ccaaaccatc
   100861 ttcagtctgt acgacacttc ttagaaaatt gaaaaattca atttgcatac aacctcctat
   100921 tctttaggtt ctaccgttgg aaccgtccag tcaggattgc cctctgcatc aaatttcatg
   100981 atatagaatt catgattcaa cagaacggct acgttgattg ttgcgattgt accaccccac
   101041 tggttgaacg cccaaacggt ttcaacatcc ttgaattggc gacggccatt tacgatcaca
   101101 ggacgttttt gaacgtcacg atacatatag aagtcatcgc ttacattctt gcaacgaatg
   101161 aactctccat tttctttcat gtagcgcaaa gcgctcgcaa gctcaaatgg ttctgtgatt
   101221 tttgtaaggt ctagtaagtt atctgtgttt tgatttgttt ctgccatgtc tattctcctt
   101281 tgtctgctgg tttagtttgt tcatcaagca gagcttccag ctcatccact cgtgcttgaa
   101341 gtctttgatt ctcttccctt tgctcattca actgaatact caagatatta cttgtaatca
   101401 tcgaatttgt tgaagttgtt gacatttcac taattgtcat ttgtaaggct tggttaagct
   101461 gttctgtgtt cattttctaa gttctccaat ctgtgtgttc gttttctatt ttcaagagca
   101521 agctcctaaa ttgctttaag tgcgatattg gtcaacatgt tgttattcat gctattgttt
   101581 tctccatttt ttctattttt tgatttaatt cttgaatagc cttgattaag taaggaacta
   101641 aagcggtata gtcgatatgc agatagccat ctggattctc aggatctcgt gagacaattt
   101701 ttggaacgat ggtttcagcc tcttgagcta ttagaccaat ctcctcatgt ttcttatttt
   101761 cgatgaaatc aaatgcaacc attcttaatc tgttgatttt gtccaaggct ttcacagctg
   101821 tatctgtgat gttctctttt aagcgtctat ctgatttttg ttccatccaa tacttca
//
LOCUS       DAVKZI010000002        87720 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKZI010000002 DAVKZI010000000
VERSION     DAVKZI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 87720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.002"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(21..971)
                     /locus_tag="VXB18_000124"
                     /pseudo
     CDS             complement(21..971)
                     /locus_tag="VXB18_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1048..1503
                     /locus_tag="VXB18_000125"
     CDS             1048..1503
                     /locus_tag="VXB18_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0381419.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYSNPAYFY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            1668..1967
                     /locus_tag="VXB18_000126"
     CDS             1668..1967
                     /locus_tag="VXB18_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0381420.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            2227..2550
                     /gene="tnpB"
                     /locus_tag="VXB18_000127"
                     /pseudo
     CDS             2227..2550
                     /gene="tnpB"
                     /locus_tag="VXB18_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(3279..5006)
                     /gene="ezrA"
                     /locus_tag="VXB18_000128"
     CDS             complement(3279..5006)
                     /gene="ezrA"
                     /locus_tag="VXB18_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0381421.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(5088..7034)
                     /gene="gyrB"
                     /locus_tag="VXB18_000129"
     CDS             complement(5088..7034)
                     /gene="gyrB"
                     /locus_tag="VXB18_000129"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0381422.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGYTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(7049..7612)
                     /locus_tag="VXB18_000130"
     CDS             complement(7049..7612)
                     /locus_tag="VXB18_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0381423.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(7697..8251)
                     /locus_tag="VXB18_000131"
     CDS             complement(7697..8251)
                     /locus_tag="VXB18_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0381424.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(8262..9485)
                     /locus_tag="VXB18_000132"
     CDS             complement(8262..9485)
                     /locus_tag="VXB18_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0381425.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(9522..11972)
                     /locus_tag="VXB18_000133"
     CDS             complement(9522..11972)
                     /locus_tag="VXB18_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0381426.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(12172..13101)
                     /locus_tag="VXB18_000134"
     CDS             complement(12172..13101)
                     /locus_tag="VXB18_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0381427.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQVFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            13241..13528
                     /locus_tag="VXB18_000135"
     CDS             13241..13528
                     /locus_tag="VXB18_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0381428.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(13562..14896)
                     /gene="ciaH"
                     /locus_tag="VXB18_000136"
     CDS             complement(13562..14896)
                     /gene="ciaH"
                     /locus_tag="VXB18_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0381429.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(14886..15560)
                     /gene="ciaR"
                     /locus_tag="VXB18_000137"
     CDS             complement(14886..15560)
                     /gene="ciaR"
                     /locus_tag="VXB18_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0381430.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(15669..18215)
                     /locus_tag="VXB18_000138"
     CDS             complement(15669..18215)
                     /locus_tag="VXB18_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0381431.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISAFERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(18338..18778)
                     /locus_tag="VXB18_000139"
     CDS             complement(18338..18778)
                     /locus_tag="VXB18_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0381432.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(18753..19622)
                     /locus_tag="VXB18_000140"
     CDS             complement(18753..19622)
                     /locus_tag="VXB18_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0381433.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTTPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(19600..20100)
                     /locus_tag="VXB18_000141"
     CDS             complement(19600..20100)
                     /locus_tag="VXB18_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0381434.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(20111..20809)
                     /locus_tag="VXB18_000142"
     CDS             complement(20111..20809)
                     /locus_tag="VXB18_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0381435.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPSGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(20802..21068)
                     /locus_tag="VXB18_000143"
     CDS             complement(20802..21068)
                     /locus_tag="VXB18_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0381436.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(21134..22060)
                     /locus_tag="VXB18_000144"
     CDS             complement(21134..22060)
                     /locus_tag="VXB18_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0381437.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(22135..22950)
                     /locus_tag="VXB18_000145"
     CDS             complement(22135..22950)
                     /locus_tag="VXB18_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381438.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVILGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKETVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(22954..23274)
                     /locus_tag="VXB18_000146"
     CDS             complement(22954..23274)
                     /locus_tag="VXB18_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0381439.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(23481..23561)
                     /locus_tag="VXB18_000147"
                     /pseudo
     CDS             complement(23481..23561)
                     /locus_tag="VXB18_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(23605..25602)
                     /gene="metG"
                     /locus_tag="VXB18_000148"
     CDS             complement(23605..25602)
                     /gene="metG"
                     /locus_tag="VXB18_000148"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0381440.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(25726..26985)
                     /locus_tag="VXB18_000149"
     CDS             complement(25726..26985)
                     /locus_tag="VXB18_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381441.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(26987..27688)
                     /locus_tag="VXB18_000150"
     CDS             complement(26987..27688)
                     /locus_tag="VXB18_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381442.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(27672..28871)
                     /locus_tag="VXB18_000151"
     CDS             complement(27672..28871)
                     /locus_tag="VXB18_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0381443.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            29157..30503
                     /gene="gor"
                     /locus_tag="VXB18_000152"
     CDS             29157..30503
                     /gene="gor"
                     /locus_tag="VXB18_000152"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0381444.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            30700..31236
                     /locus_tag="VXB18_000153"
     CDS             30700..31236
                     /locus_tag="VXB18_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0381445.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            31291..31371
                     /locus_tag="VXB18_000154"
                     /pseudo
     CDS             31291..31371
                     /locus_tag="VXB18_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(31440..31655)
                     /locus_tag="VXB18_000155"
     CDS             complement(31440..31655)
                     /locus_tag="VXB18_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0381446.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            31753..32073
                     /locus_tag="VXB18_000156"
     CDS             31753..32073
                     /locus_tag="VXB18_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381447.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(32104..32442)
                     /locus_tag="VXB18_000157"
     CDS             complement(32104..32442)
                     /locus_tag="VXB18_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381448.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(32454..33173)
                     /gene="trmD"
                     /locus_tag="VXB18_000158"
     CDS             complement(32454..33173)
                     /gene="trmD"
                     /locus_tag="VXB18_000158"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0381449.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGRYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(33163..33681)
                     /gene="rimM"
                     /locus_tag="VXB18_000159"
     CDS             complement(33163..33681)
                     /gene="rimM"
                     /locus_tag="VXB18_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0381450.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(33786..34071)
                     /locus_tag="VXB18_000160"
                     /pseudo
     CDS             complement(33786..34071)
                     /locus_tag="VXB18_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(34072..34500)
                     /locus_tag="VXB18_000161"
     CDS             complement(34072..34500)
                     /locus_tag="VXB18_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0381451.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKKLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEE"
     gene            34640..34849
                     /locus_tag="VXB18_000162"
     CDS             34640..34849
                     /locus_tag="VXB18_000162"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381452.1"
                     /translation="MLVINGCGFVFLKDSLGKVNMINSYDCDGVVNDISQFSGKFLVR
                     ILSLLFDQSAYSKPRLLLRLPPLTS"
     gene            complement(35077..35316)
                     /locus_tag="VXB18_000163"
     CDS             complement(35077..35316)
                     /locus_tag="VXB18_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0381453.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(35336..35608)
                     /gene="rpsP"
                     /locus_tag="VXB18_000164"
     CDS             complement(35336..35608)
                     /gene="rpsP"
                     /locus_tag="VXB18_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0381454.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35778..35987
                     /locus_tag="VXB18_000165"
     CDS             35778..35987
                     /locus_tag="VXB18_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381455.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            36466..36678
                     /locus_tag="VXB18_000166"
     CDS             36466..36678
                     /locus_tag="VXB18_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381456.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            36762..37565
                     /locus_tag="VXB18_000167"
     CDS             36762..37565
                     /locus_tag="VXB18_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0381457.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(37621..39162)
                     /locus_tag="VXB18_000168"
     CDS             complement(37621..39162)
                     /locus_tag="VXB18_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0381458.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(39164..39646)
                     /locus_tag="VXB18_000169"
     CDS             complement(39164..39646)
                     /locus_tag="VXB18_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0381459.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(39646..40731)
                     /gene="rlmN"
                     /locus_tag="VXB18_000170"
     CDS             complement(39646..40731)
                     /gene="rlmN"
                     /locus_tag="VXB18_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0381460.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRGVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(40752..41282)
                     /locus_tag="VXB18_000171"
     CDS             complement(40752..41282)
                     /locus_tag="VXB18_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0381461.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(41438..42043)
                     /locus_tag="VXB18_000172"
     CDS             complement(41438..42043)
                     /locus_tag="VXB18_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0381462.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(42216..43253)
                     /locus_tag="VXB18_000173"
     CDS             complement(42216..43253)
                     /locus_tag="VXB18_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0381463.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(43287..44222)
                     /locus_tag="VXB18_000174"
     CDS             complement(43287..44222)
                     /locus_tag="VXB18_000174"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0381464.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(44775..45965)
                     /locus_tag="VXB18_000175"
     CDS             complement(44775..45965)
                     /locus_tag="VXB18_000175"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0381465.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(46180..47523)
                     /locus_tag="VXB18_000176"
     CDS             complement(46180..47523)
                     /locus_tag="VXB18_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0381466.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(47663..48478)
                     /locus_tag="VXB18_000177"
     CDS             complement(47663..48478)
                     /locus_tag="VXB18_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0381467.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLDLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(48530..50710)
                     /locus_tag="VXB18_000178"
     CDS             complement(48530..50710)
                     /locus_tag="VXB18_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0381468.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DVDKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIVISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(50996..51922)
                     /locus_tag="VXB18_000179"
     CDS             complement(50996..51922)
                     /locus_tag="VXB18_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381469.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(51915..52607)
                     /gene="ftsE"
                     /locus_tag="VXB18_000180"
     CDS             complement(51915..52607)
                     /gene="ftsE"
                     /locus_tag="VXB18_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0381470.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(52625..53720)
                     /gene="prfB"
                     /locus_tag="VXB18_000181"
     CDS             complement(join(52625..53647,53649..53720))
                     /gene="prfB"
                     /locus_tag="VXB18_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0381471.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVILSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGKKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(53828..54484)
                     /locus_tag="VXB18_000182"
     CDS             complement(53828..54484)
                     /locus_tag="VXB18_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0381472.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(54792..55502)
                     /locus_tag="VXB18_000183"
     CDS             complement(54792..55502)
                     /locus_tag="VXB18_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381473.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(55502..56266)
                     /locus_tag="VXB18_000184"
     CDS             complement(55502..56266)
                     /locus_tag="VXB18_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381474.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(56266..57222)
                     /locus_tag="VXB18_000185"
     CDS             complement(56266..57222)
                     /locus_tag="VXB18_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0381475.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(57226..58095)
                     /locus_tag="VXB18_000186"
     CDS             complement(57226..58095)
                     /locus_tag="VXB18_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0381476.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(58363..59523)
                     /locus_tag="VXB18_000187"
     CDS             complement(58363..59523)
                     /locus_tag="VXB18_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0381477.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(59624..59872)
                     /locus_tag="VXB18_000188"
     CDS             complement(59624..59872)
                     /locus_tag="VXB18_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0381478.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(59951..60541)
                     /gene="clpP"
                     /locus_tag="VXB18_000189"
     CDS             complement(59951..60541)
                     /gene="clpP"
                     /locus_tag="VXB18_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0381479.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(60715..61344)
                     /gene="upp"
                     /locus_tag="VXB18_000190"
     CDS             complement(60715..61344)
                     /gene="upp"
                     /locus_tag="VXB18_000190"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0381480.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(61433..61900)
                     /locus_tag="VXB18_000191"
     CDS             complement(61433..61900)
                     /locus_tag="VXB18_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0381481.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(61919..62476)
                     /locus_tag="VXB18_000192"
     CDS             complement(61919..62476)
                     /locus_tag="VXB18_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0381482.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            62601..63446
                     /locus_tag="VXB18_000193"
     CDS             62601..63446
                     /locus_tag="VXB18_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0381483.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            63505..64677
                     /locus_tag="VXB18_000194"
     CDS             63505..64677
                     /locus_tag="VXB18_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0381484.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGANPI"
     gene            64692..64937
                     /locus_tag="VXB18_000195"
     CDS             64692..64937
                     /locus_tag="VXB18_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0381485.1"
                     /translation="MEQSPQKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(64934..65738)
                     /locus_tag="VXB18_000196"
                     /pseudo
     CDS             complement(64934..65738)
                     /locus_tag="VXB18_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            65777..66694
                     /locus_tag="VXB18_000197"
                     /pseudo
     CDS             65777..66694
                     /locus_tag="VXB18_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(66734..67678)
                     /gene="manA"
                     /locus_tag="VXB18_000198"
     CDS             complement(66734..67678)
                     /gene="manA"
                     /locus_tag="VXB18_000198"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0381486.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(67810..68091)
                     /locus_tag="VXB18_000199"
     CDS             complement(67810..68091)
                     /locus_tag="VXB18_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0381487.1"
                     /translation="MDTPDEKGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            68262..68504
                     /locus_tag="VXB18_000200"
                     /pseudo
     CDS             68262..68504
                     /locus_tag="VXB18_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(68621..68968)
                     /locus_tag="VXB18_000201"
     CDS             complement(68621..68968)
                     /locus_tag="VXB18_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0381488.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(69079..70854)
                     /gene="spxB"
                     /locus_tag="VXB18_000202"
     CDS             complement(69079..70854)
                     /gene="spxB"
                     /locus_tag="VXB18_000202"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0381489.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(71061..73304)
                     /locus_tag="VXB18_000203"
     CDS             complement(71061..73304)
                     /locus_tag="VXB18_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0381490.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNADVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(73314..73685)
                     /locus_tag="VXB18_000204"
     CDS             complement(73314..73685)
                     /locus_tag="VXB18_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0381491.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(73696..74091)
                     /locus_tag="VXB18_000205"
     CDS             complement(73696..74091)
                     /locus_tag="VXB18_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0381492.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      74275..74373
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            74457..75263
                     /gene="thiD"
                     /locus_tag="VXB18_000206"
     CDS             74457..75263
                     /gene="thiD"
                     /locus_tag="VXB18_000206"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0381493.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCT
                     FAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(75472..76104)
                     /locus_tag="VXB18_000207"
     CDS             complement(75472..76104)
                     /locus_tag="VXB18_000207"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0381494.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(76097..76900)
                     /locus_tag="VXB18_000208"
     CDS             complement(76097..76900)
                     /locus_tag="VXB18_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0381495.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MPFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(76900..77424)
                     /gene="thiW"
                     /locus_tag="VXB18_000209"
     CDS             complement(76900..77424)
                     /gene="thiW"
                     /locus_tag="VXB18_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0381496.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(77429..78121)
                     /gene="tenA"
                     /locus_tag="VXB18_000210"
     CDS             complement(77429..78121)
                     /gene="tenA"
                     /locus_tag="VXB18_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0381497.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLESAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHVEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(78132..78782)
                     /locus_tag="VXB18_000211"
     CDS             complement(78132..78782)
                     /locus_tag="VXB18_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0381498.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(78784..80169)
                     /locus_tag="VXB18_000212"
     CDS             complement(78784..80169)
                     /locus_tag="VXB18_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381499.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELRLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(80170..80730)
                     /locus_tag="VXB18_000213"
     CDS             complement(80170..80730)
                     /locus_tag="VXB18_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0381500.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLFGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGVTLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(80992..81080)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(81289..81918)
                     /locus_tag="VXB18_000214"
     CDS             complement(81289..81918)
                     /locus_tag="VXB18_000214"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0381501.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     ESALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(81920..82702)
                     /gene="thiM"
                     /locus_tag="VXB18_000215"
     CDS             complement(81920..82702)
                     /gene="thiM"
                     /locus_tag="VXB18_000215"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0381502.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            82793..82879
                     /locus_tag="VXB18_000216"
                     /pseudo
     CDS             82793..82879
                     /locus_tag="VXB18_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(83029..83697)
                     /locus_tag="VXB18_000217"
     CDS             complement(83029..83697)
                     /locus_tag="VXB18_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0381503.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(83912..84000)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(84254..85390)
                     /gene="lctO"
                     /locus_tag="VXB18_000218"
     CDS             complement(84254..85390)
                     /gene="lctO"
                     /locus_tag="VXB18_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0381504.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(86015..87505)
                     /gene="lysS"
                     /locus_tag="VXB18_000219"
     CDS             complement(86015..87505)
                     /gene="lysS"
                     /locus_tag="VXB18_000219"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0381505.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(87632..>87720)
                     /locus_tag="VXB18_000220"
     CDS             complement(87632..>87720)
                     /locus_tag="VXB18_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0381506.1"
                     /translation="EPMAQQVIPKAAFGYIASGAEDTFTSFQ"
BASE COUNT        26040 a        19093 c        15984 g        26603 t
ORIGIN      
        1 cttatttcaa tctgctatag tcaattgaaa caagaacagg acaaaagagc ctcgtaaaag
       61 gtattgcaac ttggtaatac ctttttgagg tgctttttga tatgagccca tgttttctca
      121 ataggattgt actcaggcga gtagggagga agaggtaaaa gtttatgccc aaactcttcg
      181 cataaaagtt ctagcttccc cattctatgg aatcttgcat tatccataat atagtagatt
      241 gaaactagaa tagtacacat ctacttctaa aacattgtta gaattcgatt ttactatcct
      301 gatcgattta tcctattctt attttatttt actataataa ccgatggtgt ggttaatgtt
      361 ggtaagagaa acttctgaaa ccaagcttca aaaaagtcgc tcgtcatcgt ctcttcgtaa
      421 gtcattggag cgattaattc accatttgtt agacctgcaa ccaaagaaat cctctgatat
      481 cttcttccag atactttgcc tcttattaac tgacctttta atgagcgacc atattctcga
      541 taaaaataag tatcaaatcc tgtttcgtca atctaaacag gtgctaggtg ctttaaacta
      601 ttaaaattct taagaaataa ggctactttt tctggctctt gttcatagta ggtgtggttc
      661 ttttttcgag tgtagcccat agctttgagc gcatagtgga tggtagttgg atgacagcca
      721 aattcagaag ctatttcagt caaataagcg tctggattgt cagtaagata gtttttaagt
      781 ctatctctat caacttttct tggttttgtt ccttttactt ggtggtttag ctctcctgtt
      841 ttctctttta gctttaacca gccataaatg gtattacgtg agatttggaa aacgtgtgat
      901 gcttctgtta tactacctat tcgctcacaa taagagagaa cttttttacg aaaatctatt
      961 gaatatgcca taagaagatt ataccacatt gtgtactatt tttggttcat ttcactataa
     1021 taataacgat actagataat gaggaaaatg caatggcaaa cccaactttc ggagaaaaaa
     1081 gcgaatacag actatattgc tcgctatggc gtatatgcag ttatccctaa tcctgaacaa
     1141 aaacaaattg ttcttgttca agaaccaaat ggtgcttggt tcctaccatg tggagaaatt
     1201 gaagcaggtg aaaatcatca ggaagcccta aagcgtgagt tgattgaaga gcttggtttc
     1261 acagcagaaa ttggtaccta ttacggacaa gctgacgaat atttctattc tcgtcatcgt
     1321 gatacctact actccaatcc tgcctacttc tatgaagcaa ctcctttcaa agaagtacaa
     1381 aagccactag aaaactttaa tcatattgcc tggttcccta ttgacgaggc tatcaaaaac
     1441 cttaaacgtg gtagccataa atgggccatt gaatcttgga aaaaacagca taagattgac
     1501 taatactctt cgaaaataaa attcaaacca catcagcgtc gccttaccat actcaagtat
     1561 agcctgcggc tagcttccta gtttgctctt ttattttcat tgagtataaa tcaagcgact
     1621 ttattcaaaa agtgctataa tagaattaga aaaccggagg aaatattatg aagcttatca
     1681 atacgacaaa ctcacactcg caacttgtaa aaagtcagct agaaagtacc gatgcaaccc
     1741 ttgttgaggt ttattctgca gggaatacag atgttatttt tacccaagct ccgcttcact
     1801 atgaaatcct catctcaaac aaacaccgtg ctattcgtga gcctgaaatc gaaaccattc
     1861 aagaattttt cttgaaacgt aaaattgata agacctctgt tgatgaagcc aatatcaaga
     1921 cactctactc agagaaatta attggaattt caatcccaat caagtaagaa aattgagtaa
     1981 aaactcgatt tgagagaaag tccaataagt ctttccataa caaaacgcat agtaacaaga
     2041 gtttctacac ccactattat gcgtttttat cattttgaaa tctactgcaa tcaatgaaga
     2101 agcaaagatc aaactaggca gctagttaca agttacgtaa gcgcgtcata acaaggtatc
     2161 tatcctaatt ccccaacttc cagtatacta gataaaaaat aattatcgga ggaaaggtat
     2221 tgtactatga taattcaact aagtgattta ggtcaagttc accttgtttg tggtaagaca
     2281 gatatgaggt agggaataga ctcattagcc tatgtagtta aaacccactt tgaattggat
     2341 tctttctccg gtcaagtctt tctcttttgt ggtggacgta aagaccgctt taaagccctt
     2401 tactgggatg gtcaaggatt ttggctacta tataaacgct ttgagaacgg aaaactgact
     2461 tggctaagta cagaaaagga tgtcaaagct ctcgcacctg aacaagtaga ttggctgatg
     2521 aagggctttt ctatcactcc aaaaatatag tagattgaaa ctagaatagt acacctctgc
     2581 ttctaaaata ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct gttcttgttt
     2641 cgttttacta tagaacgatt tgaaggcgtt tatgatattt agctgtacga gagtctttta
     2701 aaagtgtttt gatggtttgg atttcttctt taattgattt catattacta ttgtataatg
     2761 ctttttgatt ttagtctagt ataaatagcg agaaatatct atcctatctt ctagaatgtc
     2821 ttccaaacga gaaaactctc gtaaacaaag aggttttaga ggcctattta ccgtggacta
     2881 aagttgtaca agaaaagtgc aaataagaaa tctccagatt aggaactatc cgtgagttct
     2941 ctagtctgga gatttttcaa tagacttcgt tattggacgg ttaccaagtt actcaaagta
     3001 cagatttgaa gctgcagata agactgacga aatcacttta atactaaatg aaaatcaaaa
     3061 agcaaactaa gaagctagcc tcaggctgta cttgagtacg gtaaggcgac gctgacgtga
     3121 tttgaagaga ttttcgaaga gtataaaaca ctgttttgag gtggtggata aatcggctgg
     3181 gtaaaaactc aatctcagga gaaaatgaag taaatctccc cacaactata gaaaaagatt
     3241 tgattctgct cctcacacaa taaaatcttt ttcttttatt aaaaacgaat cgtttcacgt
     3301 gttttctcat atgaggtaac aaagcgattg gttacaccag gctctgccac ttccaatgct
     3361 tgagaaatct tgtcaaatga agcgtgataa tcaaattctt tttcaaaaat atctaaagct
     3421 tcgttaaatg cttcttgaat gcgttcatca aatgagcgat agcggttaga atattgcaag
     3481 agttgctctg tcaaagttgc atattgtaca atattataag tttccgtttc taaagcttcc
     3541 atatcattcg ttgcaatttc aagaactcgg gtaacagatt caatgttaat cattttttgt
     3601 tctaactcaa ccattaaatc ctcggtatta ttgcttgccg taaagaataa cttcaagaaa
     3661 gtttgtggaa tacctggcag attgcgtttt tccatgtatc gcttgatagt atggagacga
     3721 ttgacataaa cattggcctt ttgacgtgca ttaatatcat ctttctcaat ttgtgtcagg
     3781 cgctcactaa ctgaaatttg ctcatcttca atatctttta gttgagtttg taaatcctca
     3841 agattttctt caagaactga ataagcttgg gttggttctt cttgatttga agttacctca
     3901 acaatagctg cctcaaaact ctctaattct gtctgaatac gacgaacatg gcttgcagct
     3961 gtctcaggaa gtaaataggt cttgttcaaa cgtgcaatat cttctcccaa taaagtatta
     4021 ttctctttca tatgttgaag gtaagttgga agagttgcaa gtagattttc cactactttc
     4081 tgagcagcaa tttctcgagt aaaaatatca tacaaggcat tgatttcctc ttgtgcctgt
     4141 ccattctcat attcggcatt atccaattcc aactgacgaa tattctcttg gtttttcttg
     4201 aatgcttcat aaagcaagtg gaaacgcgct tcaatatccg tttcaacaaa atgataatta
     4261 gcatcaatta gtttacgata accggattcc aaatcctgta attgatctgg caattctgta
     4321 gaaagcgtcg taaccaaggc tggaacacga tccacaatat gacttaaggc caaaatgtga
     4381 ttttctgtat tatccaaaat cactgcggct tccacagggt cacccgatga attcaaggtt
     4441 acaaattgtg aaaattcaga ttggatattt tctaattgtt tttcaatttc atccaaggct
     4501 tgaccatact gttctgaatt ttcagcaact ctatgctgaa gttcctcaaa taaatccaaa
     4561 gcatgaagaa cacgaccact atttttagat tcttgcttct ctaagtctgc caaagcattg
     4621 cgaattgccg caatatcttc ttcaatcaaa gtaatttgac tctcaatttg gtcaatttga
     4681 tgactggcct tgagaaaacg aaatgaatgg ttataacctt ctgcttcaaa gagattattt
     4741 tcaatatcgg caaaagagtt gagagataaa tcgacccatt tttgattcca ttcacggaaa
     4801 gccacttgac tttgtccaat caagtgcata ttttttacag cttctacttc atcatttact
     4861 ggaagattgt atagttcttc ttttctttct tctagcgcct ctaatctccc ctcgtttcgc
     4921 ttacgtagaa agattgccac tacataagcc agaactaaaa tgactgcaat tgcaaccatt
     4981 aaataaatta gttgtccatt agacatatca aactcctttt ttacttgaaa caatcgtaac
     5041 gattatatca tattttttag accaagggaa ctacttctcc ctatttttta gacatcaagt
     5101 gtactataga cagcattttc ttcgataaac tcacgacgag gctctactcg atcccccatc
     5161 aacatatcaa agattttatc tgcttctgca gcatcatcta cagaaactct agccatcaag
     5221 cgatgttcgg gatccatggt tgtttcccac agctgatgat cgtccatttc acctagcccc
     5281 ttataacgct gaatagtcgg tttggtacga ccttcactat aacgggctaa agcttcttgg
     5341 agtttgattt cttgatctgc acccggctgg atatattctt taatctcgct tccaaccttg
     5401 acaccataga ttggtggttg ggcaatataa acataaccag cttctaggat tggtttcata
     5461 taacgataaa tcaaggttaa aagaagggta cgaatgtggg ctccatcgac atcggcatcg
     5521 gtcatcaaaa cgagtttttg gtaacgggct ttcgaaacat caaattctgc gccaaatcct
     5581 gttcccatgg ctgtgaaaag actacgaatt tcttcgttgg ctagaatctt atccatactt
     5641 gctttttcaa cattcaaaat cttaccgcga attggaagga tagcctgaaa ctcacggtta
     5701 cgaccagatt tggctgatcc accagctgag tctccttcga cgatgaagag ttctgtttca
     5761 gcagggttat tagaagaaca gtctgctagt ttccctggaa ggttggaaat ttccaaacca
     5821 gattttttac gtgtgacttc acgcgcacgc ttggcagcca cacgagcctt ggcagccaaa
     5881 attccttttt ctacgatacg tttggcaatc tgtggatttt ccatgaggaa atcggagaag
     5941 gcttcactga agaggcgatt ggtaatcttg accacttcgc tatttcccaa tttggtcttg
     6001 gtttgtcctt caaactgtgg atttgggtgt ttaactgaga taactgcagt taagccttcg
     6061 cgaacatctt cccctgttaa attatcttca ttgtctttca gtaacttatt cttacgagca
     6121 taatcattga taacacgagt cagtgccgta cggaaacctt gttcatgcgt tccaccttca
     6181 tgggtatgaa tattattggc gaaactcatg acattttcat ggtaacctgt tgtgtactgc
     6241 atggctacct caactgtgat atcatccatc tcaccgtctg tatagattgg tgtatcaaag
     6301 attacatcct tgttctcgtt gatatattca acgtaactag caatcccacc ttcataatga
     6361 taatgcttgg tttgttccaa accttggcgc ttatctgtaa ttgaaatttg aagaccgcga
     6421 tttagaaagg ccaactcttg aatccgttta tttaatttat caaaatcaaa gattgttgtt
     6481 tcagtgaaaa tttctgggtc cggtgtgaag tgaaccgttg ttccagttct atctgtatac
     6541 ccaaccacct caaggtctgc aacaacatga ccacgacgat attcttggta atgaatctta
     6601 ccgtttttat ggacatgaac gtctaattga gtggaaaggg cattaactac tgacgacccc
     6661 accccgtgaa gaccacctga aaccttgtat ccaccaccgc cgaactttcc tccagcatga
     6721 aggactgtaa agacggtctc aacagcagga cggcctgttt tttcctgaat atcgactggg
     6781 ataccacgcc catcatccac aacagtaatc gaatcatctg gctcaataaa aacttgaata
     6841 tggctggcaa atcctgccaa ggcctcgtca attgagttat caacaatttc ccagactaga
     6901 tggtgaagac cttcttttga ggttgatcca atgtacatcc ctggacgcat acgaacagcc
     6961 tctaagccct ctaaaacttg aatttgactg gcatcataat cctgtgcctg cagatttttg
     7021 atttcttctg tcatcttatt cctttttctt atatgtctaa tacttgtctt aaattcacga
     7081 tactggtaaa caagtgggta tcaagtcctg cagcttgacc tgcttcgata tcaatcggcc
     7141 gatcaccaat gacaagacca gagctaatct gatacttttc tcttaaataa agcatggatt
     7201 cgggatttgg ctttctctta aagcctgaac tagaagtcac cacttctgta aaataagctg
     7261 ctatagaggt tttttctaaa atttccaaaa cctgatcatt tcgatgagag accaaaaaat
     7321 gacggccacc ttgatttaaa atgtcttcca ataggtcaga aactccttca aataaaatcg
     7381 ggtgttcaag ctctctggct tcattttcct tgtacttttc taaaaaattc tctaaattgg
     7441 gagcgaatgt ctcaatcgca aaaggagtag aaacctttaa agcttgatag acactgtcat
     7501 ggtcttgtgt gataccatac agtgccaatg tttcaacaaa tgcagctgtt gaagtttcat
     7561 aattatccag taaagttcca cctaaatccc agatgtaatc gtgatatttc atacccttca
     7621 ttatagcatt tttttatgaa aaaagcgatg atttccctga gttttccaca taaaaaacga
     7681 gagaataact cccgttttac tgatttttac caaagacatc tcgatagagc attcctgttc
     7741 gtaaactctc tgcgtcccct cctagttgct ccaccaactc gtaggcaaag gcaagggctg
     7801 ttgaaggacc ccgactggtt gtcaactgac catctaccac tactgtttcc ttgacgtagt
     7861 gaccatcaag gatttgctct tgaacgccgt cataacaagt gtatcgctta tttttcaata
     7921 tctctgcttg attgagggca attggtgccg cacaaatggc tgctagtttc ttcccttctt
     7981 gctcgaagct ttgcaattct tgaatcaagg tctgattatc acgtaaatgt gcagaaccag
     8041 gcatacctcc aggaagaaca atcatatcat agtctgataa atctccatca aagacatgat
     8101 ctgctcttac ttggattgca tgcgaacccg ttacttgctc ttcaaaacca accatatcac
     8161 atgtgatatt ggctcgacgc aagacatcta caactgtcaa ggcttcaatt tcttcaaagc
     8221 cctgagctaa cataactgct acttttacca tgattttctc cttatttaat ttgttttaat
     8281 acaacctttt tccgtttgaa tgggactttt ccgctctttt cttcagctag attagtctgg
     8341 taactcatcg ataaaagcaa accaacacca atcagattac tgataatagc tgatccccct
     8401 tgcgaaatga aaggcaaggg aatccccgtc aaaggaagta gtccagtcac agcaccgata
     8461 ttctcaaaga tgtggaagag caacatcata atcaaacctg tggaaatata agtgtagaac
     8521 tggttatttg atttaagagt aatcttcaac atacggtaaa tcaacatgag atagagggca
     8581 ataaccagga cagagccaat aaagccaaaa tcttctgcaa taaccgtaaa aatcatatct
     8641 gactctcgaa ctgggataag cagattcgaa gcattaaatc cctgaccaaa taagccacca
     8701 ctcccaatgg caatctgccc ttgagcctgc tggtaagtcg ttgtttgggc aaactcaaag
     8761 ggattgagcc aagccaaaat ccgattaatt tggtaggtcg gcattccaat ctggtgaaga
     8821 aaagctcgtc cgtccttgct aataaagata gctaagaaac cagcaactcc tgttacagca
     8881 gtcacaaata ctgggataat aattttccaa gaaacccctg ataataaaac gattcctgag
     8941 aaaatggcta caaaaaccaa agccgtcccc aagtcacttt gaagtgctaa aagaactagg
     9001 actggaatgg taaagagaat catccagaaa attaacaaaa agtccagcgg aaccgtgcgt
     9061 ctccattcct tatgtttctt tgtaaattgg acaatgacac gagccaacat gaggatatag
     9121 gatatcttca taaattctga cggttgaaat agggtaattc catttattga tacccagttt
     9181 ttggcacccg ttgatgcaac taagcttgga ttataaaata caatcggcaa gatcataagt
     9241 cccaagccta aaatatatag aaagggggtc accttccaaa gaaattctgt attaaagagc
     9301 atgaccacaa aaccaatcac aagccccaag gcaatccagg cgacctgctg ccctaaaatg
     9361 ggcagaatat tattgggata atcatgacta acggctatat agatagccac cacaccgatg
     9421 accagtagaa aaaatactgg caagagcaaa ctgtaatcga ctcttgagtc gagagaacgt
     9481 ttcatatata ctaaccttat actttcatac aatactattt atcaaagttc attaaaaaat
     9541 ctatcaatag cctcgtcaac ttcggatcga gagatggttt taacagtcgc ttcttctgct
     9601 agagatgcta ctatttgttt gccgtatcgt tttccgacga ttctcctatc caaaataaga
     9661 gttaaggaac gttggtattc acgtctcata cttcttccca aagcctgttt taaacgaata
     9721 atggccattg gcaattgata atcataaaag gcatttttcc cttcttgatt cagttcttga
     9781 ttaatctttt tcgtcaaggg ttcttgagga ttttggaaag gaagcctcgg tacaacttga
     9841 atcacaaaag gatggcttga aaaatcaact ccctcccaga aacttgctgc accaagcaag
     9901 atttgttgtt cacctttttc aaagcgtttc tttagctgat gaacatcccc atttttatac
     9961 tgggccaagt ggctaactgt aagtaaatcc gatactgcta gaagcatgtc tttagcggta
    10021 aagagaacca aaatcggttg ctggaaagct tgaatttcca ctagtaaagc agctacctct
    10081 ctggcataga cttctaagga ggtttctgtt accagaggga aatctttgac catgaccact
    10141 tcttgttcct gttttccccg agattcaatc ttgacaaatt tagcttcagg atagcctaaa
    10201 aggtctgcca aagaaaccct ctgactaatc tcaagagtag ccgatactcc caggacttgg
    10261 caactctcag gaagtaaaga ggacagaaga gtacggcctg attttgtaga agaaatctga
    10321 attttctttt gactcgtttc agttacttca agccagtaat caccttcagc tgtaaaatag
    10381 cgaaccagct catcaaagcc ttctacttct aattctgaaa aatactgatg gagattgtcc
    10441 agagaatcta agatattttt cctagattta ccagactgaa attgttctat caagtagaga
    10501 cactcaaagc gaatactttc tagtatccgt tgttgaaccc tgttttcttc tcctactaaa
    10561 gccttatcaa ttaaatcgat aatagattgt atatcgtagg tctcttgaag cagattttct
    10621 agagctaaca aaatcttttg gacttcatca ataatcagta aacggtcact gacaaattca
    10681 ggattatctt caagtctggt cacgagatag gcatgattag tcactaaaag cttgcaagtc
    10741 tctgcccttt cttgactacg tttccaaaaa tcttccgtca caaataagct ctgggatgat
    10801 aaattcccat catgacgaag gtctgctaga aaatgttggt aacggtagag ttgcccgatt
    10861 tcatccaaat ctcctgtctc tgtctcagta agccagacca agacttgcat tttaaagcgt
    10921 ctaaataagc gattttcatc attttcctgc aaggaatgat aaaaggcatc caacttcaga
    10981 taattttgtg gtccctttaa gctatgaata tctgtatgga acacttcctt gagacgttta
    11041 ccttcttctt ccatgatttg attttgaaga atctttgtcg gaacactaag aacaatttgt
    11101 cgctctttgg attgagataa agcgggtaag agatagccat aggttttccc aatccctgtc
    11161 ggcgcttgaa tcagaaagac aggttcatct ttcaatagca agccaacctc tttagcaaaa
    11221 ctttcttgtt cctccctcac ttcaaggttc aacagagaaa tatttttaga aaagtcttga
    11281 gatagttttc gtagctccag agaagctgcc gttttcttaa aatacagacc ttgaacttgg
    11341 accaagtctg gagaactcag gatagattgg ttgcgataag tttcctcaat aaccaggtag
    11401 gactcatata ggagagcgtc agccatttcc agcaagcgtt ccaagagacc tttaggaagc
    11461 tgggtcatct tttcccgtaa aaaaagaagt aattctgctg tagcttgggc atctgaaagg
    11521 gctgtgtgtg cgtgtttaag aggaattcct aattctcgac acaaaatcgg caagctatat
    11581 ttttccagtt cagggaaaaa gacctgggcc aattcgaccg tatcaacacg agggtttctt
    11641 agctcatagc cttcaaaaaa taaattttcc gccaagagat tagcatcaaa ctgaacatta
    11701 tgggctacaa aaatcccatc ctccaccaag tcaaatattt ttctggcaac ttgcgaaaaa
    11761 tcaggtgctt gcgccagacg ttggtctgtc aatcctgtca gttctttgat atgagcatcc
    11821 aagggttcat gtggattgac atccgtcgta tagtgatcga cgatttctcc gtcctcaatc
    11881 acgacaattc ccacttggat aattttagcc ttactacctg tgctagttgc ctctaaatcc
    11941 accacaacat agcgattacc aatcgttttc attataaaaa attataccaa aaaaagggcc
    12001 atttggcacc tgcaaacata ggataatttt caaactcaag aacactactt ttcttaaaaa
    12061 tcccatcgaa tagagcattc tagcctgctg atttttgtaa aatagtgaag aaatacgaaa
    12121 aattgagaga aaaaatgttt gcatcttcct tctctcaacg aatcatgtat tttatctaac
    12181 catgtcagga tcgtagtcat aaaatcctgt atcaaggaaa cggtttttag ggtgaagttt
    12241 acgaacttct tcatccagca agaagacttg atcatggcta aagttgccct cttgaatcaa
    12301 gttacgcgct tggataaaga gttttgcaat ctcaacaaag ttctgaccag gagtgtagag
    12361 cccttctagt ttccagcgag taaagccatg ctccaccaat tctgttaatt tgatcatcaa
    12421 atcaaggtca ttgttggcaa agatatgggt cccatgatta tcttcaaaaa tggaatagtg
    12481 gctctctgga tcacttggct cagccaagaa gaggtcacgt ttatgcgtct tttcatcatc
    12541 gatatgtgta aagttatagt agttttgcaa gagtggacgt ttagaatgat ggatgacgct
    12601 agcaccgtaa accaaaactt cagcaggaat ttccaaaatc tctggcattt tgaaaagttc
    12661 agctgatgga atttcacgcg ccaaaacagc ctcagatgcg ccagcctttt gtccccagaa
    12721 gttaatctga cgactgctag ttaccatggt tgaagcatcg tagatggtct taaatgaata
    12781 accatcgcgg ttaactacgt aaaagacgcc tgcatcccca atcgtaatat agtctgtctt
    12841 gatttcttcc aagaagtcta agaaaggctt gatacggtcc atcatatctt ggtgcatgag
    12901 agcattgacc gcaacgagca attccttacc agcatcatga accaacttag cgatttcacg
    12961 taattggtca taactaaagg tcgttggcag acgaaggcca aaatctttct caccgacata
    13021 gatacggtct acgccagctt cgagtagttg ttcaacttgt tcaatacttt cagcagttgc
    13081 tgtaatgaca atcttttcca taagaaaaat tataccacat ttctccaaaa tcagccatgt
    13141 tttgaaaatg aaaagggact ttattctttt tgtaaccttt ctgtaataat tctctgccga
    13201 aaaaatgata aaataggtat gtactgttaa ggagagaatc atgcccgtaa gaaaattaca
    13261 atcctatgag gtagactatc aagaagaatt aaaccagcag cttcctcatt accaagctta
    13321 tacacctgaa gcgcaatctg atgccaatct caaggaaatc ctatttttta ttaatatcgc
    13381 tgttttttgt atctgtattg ctatctttag ttttatcttt ttagcattaa aattatcaac
    13441 tgctcttgcc tttgccgcag caatcggatt cagcttactt gttttaaaag ttcaacggtc
    13501 tattatcaaa cgaaaacgta gaagataaat ccaaaatatc gccccaattg gagcgatatt
    13561 tttatttttt ctttttagat ggtgtctgaa tggcaatctt cacttcaaag attgttccct
    13621 tgggtttatt atctttgaca gtaacagttc cttttagagc atctacaatt tgcttggcta
    13681 gggataatcc taatccaaaa ccaccttttt gccgggttct agccttgtct actcgataaa
    13741 aacggtcaaa aattttcttt ttatcttctg tcgaaatacc gattccatta tcagaaacaa
    13801 gtaaataaag attgcgatcg gtcgccgaga taagaaaatc aatttcacca tcctcctcag
    13861 tatacttgac ggcattatcg aaaagaatgg tcatcagttg tttcagaaga agctgatctg
    13921 tgacaattgt tcgatggata cgattttcaa aacggaagac acgattattt tccgaagcaa
    13981 tcatctcgta gtttgtgaaa gttgtattaa aaaagctagt tggaacttct gcaagctccg
    14041 gcttaatccc atcatctctc cgagctaagt tcagcaagct tgtcgttaaa aaacgcatat
    14101 ttcggacttc ttccaaactc gatgcaatgc tttcgctcac atccataatg gtagcttctg
    14161 gcttacgaaa aagggtctct aagcgatttt gcaaaactgc gagtggagtt cgtaactcat
    14221 gactggcatt ttccacaaaa gactgttgct tctgcatact ctcaagcagg ggcctaacac
    14281 tgaccctagc tagatagaga ctggcaagta aagacaaaat ccagaaacta gccatcacga
    14341 ccacaatcaa ttgctcatgc ttttgactag cctgctccaa ctgactggta ttaatcaaga
    14401 cagcagcata ctttatattg gttgaaaccg aactaatatt ggtctccatc aaaatcacac
    14461 gatagatttc ttcctgccca tagctattaa aaacctgaat ctggtagata tgtcctagtt
    14521 ctttcttttc taacttaatc ttatccaagc ccaaaaatcg atttccagaa agaagttgag
    14581 taaagtcttt atcaaagaga atgacttccg tattggaact gacattaggt tttatttcta
    14641 ctttactagc gtccgcccta gcattttcta aatctttaat ctcttctgtt gccctattta
    14701 tagccagctg aataactgct tgaggatttt cactcagtcc atgaagctta tcgtccaccg
    14761 aagtataaag actcgaatgc atgacttgta aaataatcag agtcattgta gaaaaaatca
    14821 gggtgaagac accgaagttg cggataaaat aactaaagtc atccgcatac catgtttttt
    14881 taagtttact gaacatcttt taaaagatac ccaacactac gcaaggtttg caaattctct
    14941 gcaaaagtgg ttccctttaa tttcttacgg acttttgaaa catagacttc gacaaccgaa
    15001 atcgttgtat cactatcaaa tccccataga cggtcaaaaa tctgcgtctt aggcaaaatc
    15061 acattttgat tttgaaggaa ataaactagt aaatcgaact ctttccccag caattcgaca
    15121 ggagtatctt caactttaac ggtattggtt gataaattaa ccacgatatt cccataagtc
    15181 aaggtgtttt cattaaactt ccctgaacgt ttgagaaggg cctgaatccg cattttaagt
    15241 tcttctaggt agaaaggttt ggtcagataa tcatccgctc ccagttcaaa tccatgtccc
    15301 ttgtcatcca aactttcctt ggcagtcata atcagaactg gtgtcgtaat tcccttttca
    15361 cgcaattctt ttaagacttg gaaaccattt ttttctggca acatcaaatc cagcaaaatc
    15421 aagtcataga caccactctc agcttcgtag agaccttctt ctccatcaaa tacctgcata
    15481 acatccgcaa aatcgtctaa aaagtcaaat actgaatttg acagacctag gtcatcctca
    15541 accaataaga tttttatcat gagaaactcc tccttattaa aactattata ccaaatttgc
    15601 cttaaaaaaa actcaactct ctgcatttta catgagatag ctgagttttc tttttatttt
    15661 aggcttattt atgcatttcc gtattgaaga acaactgctt cgactgcagc tttttcacgg
    15721 ctaatcaagt caacacgcgc tgcaatttcc ttgattccca taccgatgtt acggctaaga
    15781 gcaaggtcag aaagttgcgg ttcaaagaac tccttgtatt ccgccaagcg ttgctgagtc
    15841 ttaaatacat gagcaggaag gataacaaag ctatcaaagc tcatatctcc tccaagggct
    15901 gccttaatcc aagcccagtt ttcacgcgcc caagaccaag ctgttttctg agttgcttga
    15961 tgagctagga attggtaata ccaagcagac aagtcctgtg gtttgaccac aaatttgtcc
    16021 ttccaagaag taatcaagtt ttggatatta tccgcatctg tactgtatgc aagagctgct
    16081 gccaactggc gtttaaagac agcatctgtt gcgtgagtat aagtatcaag ataaagtgct
    16141 aacaagtctt tagtctcatg atgtttcatc tcattaatca gaacttgtga gcgaatagct
    16201 gctgggagtc ctgcaagatt ctccttgtgt gttgcgaaga tttggctagc gacttgacta
    16261 gcttctgcat catttgagcg aatcatcatc gaaacagcca gctgacgaac caattcatcc
    16321 tcatctgatt ctccgtcttt agcttcaaaa ccaagacggt catagttatg acgagccaat
    16381 ttagcaacca gtcctttgaa ggctgtttca gcatccgttc cttcatcaat aaagcgctca
    16441 aaggctgaaa tcacttgaga aacagctgaa accaccagat aagactcttc cttagcaagt
    16501 ttatcaagaa ctggaagcaa gtctgcataa gaaatgtgcc ctgcctcagc caacaaacga
    16561 cgttcttgaa caatttgcag tttgcttgtg ttatcaagtg tctctagctc agcaagaaca
    16621 gcttctaaca agtctccttg atagtcggta atatagtggg cagtattttc agtgttgaga
    16681 cgaagagctc cttcattttc agcaagaaga gctgcgtagc cagggatttc gatactttca
    16741 gtttcgagtg tatcaggcaa gcctttccag ttgctattga ggggcaccac ccagagacgg
    16801 ttcttgtctt cgttctcacc gatgaagaat tgtttttgtg aaatcttcaa gacatcattt
    16861 tcaactttaa cagtaagaac tgggtaacca ggctgttcca accaagaatc catgaaggct
    16921 gcgacatcac gtcctgacgc ttgaccaagg gcatcccaaa ggtcactacc aatggtgttg
    16981 ctgtattggt gtttttcaaa gtaggcgtgc aaacctttag caaaatcagc atctcctagc
    17041 caacggcgaa gcatatgcat gagacggctt cctttggcat agacgatagc gccgtcaaag
    17101 agtgtattga tttcatctgg atgtttaact tcgacgtgga cagactgaac gccatcagta
    17161 gcgtcacgtt caagagcaag aggtactcca cctgtttgga aatcttcaaa gatattccag
    17221 cttggttcga tggtatccac acagacgtat tccatcatat tagcgaaact ttcattgagc
    17281 caaaggtcat cccaccattt catagtcacg aggttcccaa accattggtg agccaattca
    17341 tgggccacaa caagggcaac ttgttgacgg ctagcaaatg tagagttctc atcgacaacc
    17401 aagtaaactt cacggtaggt cacaagaccc cagttttcca tagcaccagc tgagaagtca
    17461 ggaagggcga tgtggagaga ttgaggaatt ggatacttaa ctccatagta atcttcgtaa
    17521 aactcgatag agcgaacagc gatatccagt gagaaatcaa gatttgaaag tggatgtgct
    17581 ttggttgagt agacacctac cagggtacca tttttagttt tagcggtcac cccttgcaaa
    17641 tcaccagcaa caaaggccaa caagtaagaa gacatgcgag gtgttgtctc aaacttccag
    17701 atacctgttt ccttacggtt ttcaacatcg atttctggca tgtttgacaa ggccaattca
    17761 ccttctgctt ggtcaaagcg aagagagagg tcaaaagttg ctttggcttc aggctcatcc
    17821 acacatggga aagcttcgcg cgcaaaatgg ctctcgaact gagtagacaa gacctccttc
    17881 ttgactccat caactgtata ataagaaggg taaatccctg tcatgttgtc tgtaatttta
    17941 ccagaaaagg caagaaccaa ttcaacttga ccagcctcag ccaattcgat atgaagggct
    18001 tcattgtcat ggtcaactgt aaatggacga gcttgacctg caacttctac agaggtgatt
    18061 tccaagtctt tttggtggag ggagatgcgg tcactctgtg cttgaccagt gatggtcact
    18121 ttcccagaaa aagtcttggt ctcacgactc aaatctaaaa ataaatcata atgttcagga
    18181 acaaattgct taataaaatg ttcaactgct tgcatagttt tctcctattc taagtttaag
    18241 agctgctgct cttcttcaaa caaacttatt atatcatatt ttgcttgaga aaaaaggatt
    18301 ggacagcgat ttccaaaact ttcttccttc taatagtcta cagtgggtag accttgcgaa
    18361 attcttctaa aacaaccttg ctttcaggtg taaaagtcaa tcctgcttca cccaagcagt
    18421 ctctgaaaaa atcctcatga acctggcgcc aatagacaag tgtcttgttt ccctcacctt
    18481 ccttataggc atggtcagct gacactcgat tgaagggttt aacagaaacc tttgtaattt
    18541 cgacaatgca gacagcctga ttttgactat ctaaaatgac atcgaaggtc cctacttggg
    18601 gaagtggttc gtcttctagt acatagaggt cataggctga tgctgttgct gtcttttctc
    18661 ctttaaacac caaatccgct aaaaggtctg gttcaactcc aaaagcccag gcatcgattt
    18721 catctccgat agaaggattg atttgtttgt atttattcca catttcttgc ggtatcatgg
    18781 gtactccttt gtaatttttt actttcttct tttatgtgtt taagatgatc tggatggtca
    18841 atctctaaat caaaaatctc tggaatagaa ctgtagtgga taatgcactt gatacccaac
    18901 tgattcattt tttgtatgaa agaagtattc agatagcctg ctacagcaaa attaatcttg
    18961 ttctttcttg ctttatcctg catatctctt agcatatcta acattattgg actttccata
    19021 tcatgccatt gactgtttct catagtcgca aaaacaaagg aagtcaaatc attcattcca
    19081 actacaatct ttgaaatgcc cgtttccagt atactagata agtcaaaata cgctgacggt
    19141 aattcaatca tcgttccgac tttcccagta aagccatact gacgcaatac tgtaatagct
    19201 tgttttaatt ggtcggcatc attgacaaaa ggaaagataa cagatagatt gggggtggtt
    19261 tgataaactt ctgtaacgac atgtgcttca gcctgaaatt catccaaaca cgccagtaaa
    19321 cgcctagttc ctctatagcc aaacaaggga tgcccttcgt caaaaaactc tttagtcccc
    19381 actaaacaat tggcttctgt attcgttaat tcagtaaaac gataccaaac ttcttcatct
    19441 gagtacaggg agcagatagt ctctagataa tcttttacaa attgctgaca acttgctaat
    19501 atgatgtttt gattaagctc tctcaacaaa tattccccac gaatcatgcc gacgtggtga
    19561 aatagttgag gataaatttt ttcaagaatt ttttcgccac taagggcaag ttgatttctc
    19621 atcattcacc ttccaattca tgtaagaagt cttgtccagt tctggaaatc ctaataattc
    19681 agacttaacc ttcaagacta atggcgatgc attttcttct gtaatctctt gaatatccat
    19741 ccaaatatat ccaagtgaat cattcgcacc atcagacaca gcttccgaaa tcgtaacttg
    19801 aggtgcactc tcattcattt caacatcata caaggccatg acatggtgaa ccataaaatt
    19861 ttttaactct tctctgacga aaacatcgta gattcgagga ttagagtagc ttctaacagt
    19921 aaatcccgtc tcttccataa cttctctagt cagcgtttcc gtcagtcctt caccaagttg
    19981 ctgactgcct ccaggtagat cataccgatg ttgataaggg cctctcgttt tttcaatgca
    20041 aagtaacttt ccattttcaa agcaaacaca gtagacccca aagtgatttt tgatttccat
    20101 ccaactcctc ctacttcaaa gaccagccac catctattgt caagatttgt ccttgcatgg
    20161 cgctcgcttt tccacttgct aaaaaaagac taagctctgc tatttcctct ggttcaatcc
    20221 agcgcttgat tggtgtttca ctagccaccc agtcagctaa gccacttggt tcaaaatccg
    20281 cagcggtcat agctgtcttg actgctcctg gagcgatacc aaagacctga atcccagctt
    20341 cagcatagtc tagagccaac tgcttggtga agccagccaa ggcatgcttg gatgaagtat
    20401 aggcgtgacc acctccacct gctaggctag aagcaatgga acacatattg atgatgattc
    20461 cctttttatt ttccagcatt tgtgtcaaat aataccgagt caactctact ggaataatgt
    20521 agttgatttc aaaaatctct tgaatgtcct gcgccgtttg ttccaacagt ggtttgtaat
    20581 catccaaaac tccagcagta ttacacaaaa catccacctg agggcaccag tcaaaaatag
    20641 gttccaagtc caaggtcaaa tctctctgta aaaagtgaaa atcaccctct aagagtggct
    20701 tttcaccttg gtcaactcca taaacttgat agcccttctc taaaaagagg cgagcttgag
    20761 ccaatccgat ccctgaactc actcctgtaa tgagtacacg tttagtcatg cacttctacc
    20821 caatccgttg ccaaaacatc acaaactgtc gggctccaca tggaaaaacc ttctccttcg
    20881 ccagaaacgt tgattaggaa ataaggtgtc atttcaagtg caagcccatt ttgctcgatg
    20941 gtatcaaaga gttggacata gttttccgca cctccccaac cagttcgtac atattttctc
    21001 ttagccttta acccaggcag gatctcttca aatgtcatgt ttttctcctt taattctaca
    21061 ttcttcattt aattatagca aaaaaccgct ttatacggct ttttgaatgt gagttattca
    21121 aacctgctac tacttacggc aaattattcc ctgcagcaag ataaatttca taccattctt
    21181 ttcttgttaa gctaaagttt gccgctcggc taacttctct caagtgctta ggatttgttg
    21241 tacctacgac tgcctgcatt tttgctggat aacgcaatat ccaagaaatg gcaatagttg
    21301 aagaggttac tccatattta atagctaaac gatcaagtac ttgatttaaa gcttgaaatt
    21361 tctcatttcc aacaaaattc cctttaaaat acccgaattg taagacagac catgcttgaa
    21421 tgaccacatc gtgtaattgg caatattcaa aaatgctgcc atctcgcata gctgcttgac
    21481 tatcttccat attaacatga aaagctgatt caaatcctgg agtaaaagcc gcactcaatt
    21541 gtagctgatt aacagctaac ggctgcttga catctttttt aagcaactcc atcatcatag
    21601 gattttgatt agaaactcca aaatctcgaa ctttaccttg tttataaagg agattaaagg
    21661 cttctgctac ttggtcagat tccatcaaag catctggtcg atgaaggagc aagctatcta
    21721 gatgatcaat cttcaatctt tgcaaaatac cgtctactga ttttataata tagtccttag
    21781 aaaaatcaaa ataggtaaat tcttcaatgc gaatgccaca tttggactga atccacatct
    21841 tttctcttaa atctggacga ttttttagga caagacctaa cagttcttca caacgaccac
    21901 gaccataaat atcagccaag tcgaaggcat tgattccaac agaaagtgct gtttctacaa
    21961 gctcttcaac ttcttttaca gacttatctt ttattctcat cattccgaga acaatttctg
    22021 ataattcttt gtcatcttga ccaagagtta tgtatctcat caaatttttc tcctttaatt
    22081 tctaacattc ttcccttcat tataacaaaa aaccgctttg caacggcttt ttgactatac
    22141 ttcactccat tttatcttct taaacccacg gaacaagaca aagattccaa taaagaggac
    22201 agctaaagga ataacttttg taaggaaaac atttgaaatt cccatccact cataataacg
    22261 gagcagagaa cccaccacaa gatgggcaat aatcatactg acaaatggac gaaagaccgt
    22321 ttctttccaa ttccaaatac cgataactag cgaaatcgta aagacagaca aactatccca
    22381 gggagccgga atataaaagg ctccttcttg tatgaagctt gccattccta catatcctaa
    22441 aataactaga agaactatag tcccaacaac aatgtaagtg ccaattttca ttttaggaga
    22501 atcttggact aaacttcttc gtaaaattgt ggccacaagt ccaaatccaa tcagaaaaat
    22561 aagaagttgc cctaaaaatg tgagcaaatt gactgttaag agaggacctt tagaaaaatc
    22621 acttagtagt tgataataac gtaataccgc caggacaaga attggcgtca aaagggactc
    22681 tttgatagaa ctgcgaggtg ctcccttgag aatctctttc attatttttt taggattctt
    22741 acctagataa tcctctgcac tcatgccatc tcgttctgct tctgagaaat ctagcatcat
    22801 caaatagatc tgctctctga gatagtcttc atcatagaga aatccagcaa gattaaaact
    22861 ttcccacaac tcctcaaaat acttttgatt ctcctcagaa aactcatgta gcaaagcgct
    22921 tgtttcttcg taatacttca ttttcttcat ggtttaaccc ccattcttaa tcccttctac
    22981 tttttgactc aaatcgtccc attgttgcca aaagactgag acacgctctt ctccttcttt
    23041 cattaatgaa aaatacttcc gatctggacc atctggcgac gggcgcatgt cgcctcttat
    23101 ccattgattt ttttctaact tttgcaacaa aggataaata gttcctggaa cgatagtatc
    23161 aaatccagcc tctcgcaaag tctgaaccaa ctcataacca taccgctctt tttgaccaat
    23221 catatccaag acacaacctt caagaacacc ttttaatagc tgagtttctt tcatcacttc
    23281 tcccttctaa tctattttgt aatacctact agtaacttca cctatagtat atcacttcta
    23341 cactagtttg taaagcataa tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    23401 gtcgccctac cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacag
    23461 tgttttgagc tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagcaacct
    23521 gcggctagct tcctagtttg ctctttgatt ttcattgagt ataaataaaa aaacagaact
    23581 agtctgaact agtcctgtct acttttaccc aatcacactt ccatttggta cagctggatc
    23641 aactgtgaga agggttaatt tgccatcatg ttcagctgag agaatcatac cctggctgac
    23701 atattttttc atcattttac gtggtttgag gttagcaacg atttgaactt tcttgccgac
    23761 caattcttgt tcatttggat agtattttgc aattcctgaa agaatctgac gatcttctcc
    23821 atcaccagca tccaagcgga attgaagcaa cttatctgaa ccttctactt tagacacttc
    23881 tttgacttct gcgacacgga tttcaacctt gtcaaagtct tcaaacttga tttcatcctt
    23941 gtttagtttg agctcaactt cgtccggatt ccattctttt tcgactgctg gtttattgcc
    24001 ttccatttgt tccttgatat aggcgatttc ttcttccata tttagacgtg gaaagatagg
    24061 tgttcctttg gcaactacag tcacatctgc tgggaagtca gccaaactca agttttcaag
    24121 actagaaact tcttccaaac caagttgagt caaaactgca cgactagttt ccatcataaa
    24181 tggttcaatc aagtgagcaa ctacacgaat gctggctgcc aagtggctca tgacacttgc
    24241 caattggtca cgaagagctt catccttggc caagacccat ggtgcggtct catcgatgta
    24301 tttattggta cgagagatca gagtccagac tgcttcaagc gcacgtggat agtcaactgc
    24361 ttccatgtgt gtatggaagt ctgcgattga ttgttctgca acctcagcaa gaacatggtc
    24421 aaattcagtc acaccttcta cataggcagg gatttgtcca tcaaagtact tattaatcat
    24481 ggaaaccgta cggttaagga ggttcccaag gtcattagcc aattcatagt tgatacggcc
    24541 gacatagtct tcaggagtaa aggttccgtc tgaaccaact ggaaggttac gcatgaggta
    24601 gtaacgaagt ggatctagtc cataacgctc taccaacatt tcagggtaaa cgacattccc
    24661 ttttgactta gacatttttc cgtctttcat gacaaaccaa ccatgggcaa tcaaacgatc
    24721 aggtaattta acatccaaca tcataagaag gattggccag tagatagagt ggaagcgaag
    24781 gatatctttt cctaccatat ggaagactgt tccattccag aacttgtcaa agttaccatg
    24841 ttcgtcttga gcgtagccaa gagctgtcgc atagttaaga agggcatcaa tccaaacgta
    24901 gacaacgtgt tttggatttg atgggacagg cactccccat gtaaaggttg tacgagatac
    24961 cgccaaatct tccaagcctg gctcgatgaa gttgcgtagc atttcattaa ggcgaccatc
    25021 tggcgtgata aattcaggat gagctttgaa aaattcgacc aaacggtctt ggtatttgct
    25081 aaggcgaagg aagtatgatt cttcagaaac ccattcaacc tcatgacctg atggagcaat
    25141 accaccagtc acatttccag cttcatcacg gaaaacttct gccagctggc tttctgtaaa
    25201 gaattcttcg tctgatactg aataccaacc agagtattca cccaagtaga tatcatcttg
    25261 agcaagtaag cgttcaaaga cctgtgcgac aactttttca tggtagtcat cagttgtacg
    25321 gataaattta tcgtatgaga tatctagtaa ttgccagagt tctttaactc caaccgccat
    25381 tccatcaaca taggcttgag gtgtaatacc agcttcttcc gctttctgct ggattttctg
    25441 accatgttca tcaagacctg tcagataaaa tacatcgtag cccatcaggc gtttgtaacg
    25501 tgctaggaca tcacatgcga tagttgtgta ggcagaaccg atatgaagtt tcccagatgg
    25561 atagtaaatc ggcgttgtaa tataaaaatt tttttcagac ataatttttc ctttccaggc
    25621 aaatgaaacc tgtttttcta acacttcatt atatcacatt tttaatgaat ttcgataggg
    25681 aaatccatac aaaaacaaga tagacgagtg tccatcttgt tgatctcatt cataacgaag
    25741 ggcttcaatt ggatcaagtt tcgatgcctt gttggctggc aagactccaa aaatcatacc
    25801 aacactagcc gaaactgcaa gactaaatag ggcaactggg attgatactc caacttctat
    25861 accttctatt aaaccttgca gtaacaaacc tgctaaggca gttaaaccac ttgcaattgt
    25921 caagccaatt aagccaccta acaaggtcaa aatcatggat tcaatcaaaa actgaattaa
    25981 aatattggca cgtgttgcgc ccaaagcctt acgaagacca atctcacgag tgcgctctgt
    26041 caccgaaacc agcatgatgt tcatgacacc agttcctcca acaaagagag aaatccctgc
    26101 gatggaacta ataatcgtcg tcataaaact aaacgattgt tgaatttctg caaatacaac
    26161 ggactcatct gccacctggt attctccctg ttgtaagcct gcaagctctg tcatttttcg
    26221 tgccagttct ggacccagag ttggggttaa actggtatca ttcactcgaa agacaatact
    26281 agctatttca tctatattaa aattcgcagc aagggagata ttggtagtaa taggcaagcc
    26341 accaaaccca tatatttttg accttttagc ctccggacta gtataaaccc caatgacccg
    26401 gtaactaaat ccattgactt ctacaacctt gttaatagcc tcttgaggag attcaaataa
    26461 actaatggac aattcctcat ctagcaaaat aacacttgca aactctttga aatcttgctc
    26521 tctcagacta cgacctgcaa taatttcatt cttaacagcg tccatgtaag ttctgtttcc
    26581 acctgtcaaa ttagcattct caaccttttt atcttgatag gtcaagatgg cattcgttga
    26641 attggttaca tagtaactat ccactccctt cagtttagct gcctcttgga cccaggattc
    26701 ttgcggtttt ggcggttcaa caggaatttc ctcttccttt ccagaaaccg taaaagatga
    26761 ttgtttctga gtaaaagaac catctttact ttttttagga gagaaaaaga cgctaatatt
    26821 tttctgagat ttagtcatat ctttattgac ttgacgagat agggaatcac ccaaagccat
    26881 aatcacaaca actgatgaaa caccgataat aatcccaatc atagtaagca aagaacgcat
    26941 cttgtgagcc atgatagatg aaaaggcaaa tttcagattc tgcatcttag ttttcctcct
    27001 ttcctaactg agcactgtca gacgaaatga ccccatcccg aatgacaatc tgacgtttag
    27061 cataggcagc aatctcaggc tcatgcgtta ccatgataat ggtttttcct tctttattca
    27121 aatcaaccaa taattgcata atttggttac ctgttttggt atccaaggct cctgtcggtt
    27181 catccgctag gataatagaa ggattgttta ccaaggcacg cgcaatggct acacgttgct
    27241 tttgaccacc agataattct gaaggtaaat ggtgactacg ttctgtcaat tcaaccttgt
    27301 ctaaatattc ctcagccaac ttgcgacgtt ttgaagacga aactcctgcg taaatcaagg
    27361 gcaattctac attttgcaga gcattgagct tcgatagaag aaagaactgc tgaaagacaa
    27421 aaccgatttg ttggttacgg accttagcca gttgtttttc accaagccca gccacttctt
    27481 gaccttcaag ataatattct ccactggttg gtgtatccaa catgccaatc gtattcatca
    27541 gagtggactt accagaccca gatggtccca tgatggctac aaattcaccc tcattcactt
    27601 ctagattgat atttttgaga acctgcagtt cttggtcacc attacggtag cttctgaaga
    27661 tattttttag actaattagt tgcttcatca gccttcacct cttttccttc ttccaaggaa
    27721 gatgttggat tactgatgac cttagcacca ttcgttaaac cagaagtgat ttcttgattt
    27781 tctgcgtcag catttcccaa tgaaacctca acttttttag ccttttgttg ttcatccaca
    27841 atccagacat aatttttact atcatccatt actagactgc taacaggaac aagaatagcc
    27901 ttagttttgc ttttaacctc aatgttgaca gaaaaaccct gtttcaaatc accaacctcg
    27961 cctgtcacat caatagtata agggtattta gaacctgtat tattcccggc tgctggacta
    28021 gctgcttcac cattgttttt aggatagtca gaaatatagc ttaatttccc agtccatttt
    28081 ttatcaggat acactttaga agtaaagctt acttcttgac ctacagaaag gttggctaga
    28141 ttgtactcag acaattctcc cttgacttgt aaattttcat tgctgacaat atgaaccata
    28201 acttggctcg cccctgttgg agatttagaa acattgctat tgacttcgac tacagttccc
    28261 tctagggtac tgagaacagt tgttgcatcc aattgacttt gagccttgct taattgcgcc
    28321 gcagcatctg cacgcgcatc acgggcatca cccaattgag catcaataga agcaacagaa
    28381 tttccagcca ctggagttgg gctttgcacc gttgcatctt ctcctcctac tggcgctggt
    28441 aactgtggag ccggagctga agcggcttca tttcgtgctt gattgagttc attgatatga
    28501 cgatctgccc tagctactgc tcgactagct gaatcatagg ccgcctgcgc ttctgaacta
    28561 ctgtacttga ctaaagcctg cccttcgctg accttatcgc ccacagaaac aaggatttca
    28621 tctaaatcac ccttactagc atcaaaataa acatattgtt cattttttgc tgttactgtc
    28681 cctgacaata aaacagagga ggccacgctt ccttccttgg caacaacaag atgagtaggc
    28741 tcatctttta gagcagtctg agaaggttgt ctaaagagta aaatcccccc ggcacccaat
    28801 acaactacac tcgcagcacc gattgctgca tacagttgcc actttttagc tttaccattc
    28861 tttttcttca taatgaaact ccttttcttt tttacaatac tttgctatta taccaaattt
    28921 ccctccagca aacaatgcag ttcagatgga aataatggca gttcaggatt aaacaatcgt
    28981 tcggaatttt gcttttctat tgtactagat atataataca ccatcttgac ttatttggca
    29041 agcttttttg caattttttg tgcgtagcag atttttgcaa tcaaatcaaa aaaagaataa
    29101 aatataacta tcaaaaaaga cgctctacta tttaaaagat tacaaaggag ttttcaatga
    29161 gagaatatga tatcattgct atcggtggag gtagcggagg aatcgctacc atgaaccgtg
    29221 ctggtgaaca tggagccaaa gcagccgtta ttgaggaaaa gaaattaggt ggaacttgtg
    29281 tcaacgtcgg ttgtgttcct aaaaaaatca tgtggtacgg ggcacaaatc gctgagactt
    29341 tccatcaatt tggagaagac tacggcttta agactactga tcttaacttt gactttgcaa
    29401 ccctacgtcg caatcgtgaa tcctacattg atcgcgctcg ttcttcttat gatggcagtt
    29461 ttaaacgcaa cggtgtagac ttgattgaag gtcatgctga atttgtagat tctcatactg
    29521 tcagtgtaaa tggtgaactg attcgtgcta aacatatcgt gattgctact ggtgcccatc
    29581 caagtattcc taatattcct ggtgctgagc taggtggctc ttctgacgat gtatttgcct
    29641 gggaagaact tccagagtca gttgccattc taggcgctgg ttatatcgcc gttgaattag
    29701 ctggcgtact ccacactttt ggtgtcaaga cagacctctt tgttcgccgc gatcgtcctt
    29761 tacgtggttt tgattcctac atcgttgaag gtttggtcaa ggaaatggaa agaacaaact
    29821 taccacttca cactcacaaa gtccctgtca agttagaaaa aactactgac ggcattacca
    29881 ttcatttcga agatggtact agtcacacag ctagccaagt tatctgggct acaggccgcc
    29941 gtccaaacgt taagggcttg caacttgaaa aagctggagt gactctgaac gaacgtggct
    30001 ttatccaagt ggatgaatac caaaatactg ttgttgaggg aatctatgct ctaggtgatg
    30061 taacgggcga gaaagaactg actccagttg caatcaaggc cggacgtacc ctatctgaac
    30121 gtctctttaa cggaaaaact actgcaaaaa tggattactc aactattcca actgttgtct
    30181 tttcacaccc tgctatcgga actgttggtt tgacagaaga gcaagctatt aaagaatacg
    30241 gtcaagacca aatcaaggtt tacaaatcaa gctttgcatc tatgtactct gcttgcactc
    30301 gcaaccgtca agaatcccgt ttcaaactca taacagctgg ttcagaagaa aaagttgtcg
    30361 gacttcatgg aattggctac ggcgttgatg aaatgattca gggatttgcc gttgctatca
    30421 aaatgggagc aaccaaggct gactttgacg caactgtagc gattcaccca acttcatctg
    30481 aagaatttgt aaccatgcgt taatcgaaac aaaagaagct gatataaata tgtctgcttc
    30541 ttttttaatg attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg
    30601 gctgttacag tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag
    30661 tataatagtt actatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat
    30721 gctatccctg ctattggggc tgctctcatt gctgttttgg cacaaatcag tcttccaatt
    30781 ggacctgttc ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga
    30841 ccgagagagg ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct
    30901 gtctttgcag gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt
    30961 tggttttatc tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt
    31021 gttaagattt ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc
    31081 agcttgcatt tcctagctgg aatggcattt gaaaaagctc ttgttgtggg ggttcttccc
    31141 tttatcattc cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt
    31201 caacgcctta aaaatcaggc ttactttact aactaaaaaa ggataccgag ttatcatgac
    31261 tcaatatcct ttttttattt tgaaaactta tactcaatga aaatcaaaga gcaaactagg
    31321 aagctagccg caggctgctc aaaacactgt tttgaggttg tggatgaaac tgacgaagtc
    31381 agtaaccata catacggcaa ggcaaagctg atgcggtttg aagagatttt cgaagagtat
    31441 tagttgcctt taaaggcatc caccatcgtt tgaaattctt catttgagag agtaatccct
    31501 ttgcccattt tagtatggtc tggactccaa gcacgaatat caaactttgc aggggcacca
    31561 ttaaagctca cacggttaat ttccttggtc caaccttttt cgttttcaga aagagtcaac
    31621 aagtgctctt cgatttcaaa tgtaaattct gccattttct tctccttttt tagtttcatt
    31681 agtttattcg taaaatcttg tagattttag gaaaatttta tataatattg atataaaaga
    31741 agggaggcca atatgagaca taaattccag caagttctag ataaaataca tgatttttta
    31801 aatggacatg accaacctga ccagactgaa accaactccc ttacagccac tattgaagag
    31861 gctatccaga aacaaaccgc tgttcacctt atcttgtctg aaacaagctt tacaggtgat
    31921 atcatcaaat atgatcagca aggccagcaa attatcgtga aaaattttgc caaaaatgtg
    31981 agccggatta tccgtataag cgatattcaa cgcctgcgat ttgtcccctc aactgtccaa
    32041 acagcccaaa aaaatagatt taagaaagag tgagatgtag ttgcttcatc ccactctttt
    32101 ttcttagcga atttgttcaa aatgtaaatg aactgcgata tgatctccat aaccacttct
    32161 ttccaagtca cgttgtaaac gataggaaat gtagtgttct gcaatggtaa tgtaacctgc
    32221 gcccaataaa cgatgttcaa ccatagattg aatcatactg atagtcgcac gttccacctt
    32281 ggcttcttgt aaatccaaaa ctaccttctt agtgacttga gcaagatttt gacgcaaatc
    32341 atctgtcaaa acataaacag tttgggctgc cttcaagatg gcttggtaaa tcttatctgg
    32401 attaaattca gcaatttcgc cattacgttt gattacttgc ataggtttct cctttattct
    32461 ttgttttctt tgatttctgc cagcattttt tcttcttcta ctgtcagttg ataatgttca
    32521 agtaaatccg gtctgcgctc gtaggttttc tttaaactct cgtacaatcg ccactgacga
    32581 atcttttcat ggtggccact catcaataca tctggcacga ccatgcctcg ataatcatag
    32641 ggacgtgtgt actgaggata ttctaaaaga cctgaagaaa aactatcatc ttggtggcta
    32701 gactccttgc caatcacttc tggaatcagg cgaactgtag catcaatcat ggtcatagct
    32761 gccaattctc caccagtgag gacatagtcg cctagggaaa tctcatctgt taccaaggtc
    32821 ttaatgcgct catcataacc ctcatagcgc ccacagataa agattagctc ttcctcttga
    32881 gccaaatctt cagcataagc ctgatcaaac tgctttccag caggatcgag gagaataacg
    32941 cgcggatttt tcttttcaat agcatcaaag gaatcgaaaa taggttgtgc tctgagcaac
    33001 ataccttgac cgcctccgta gggctcatca tctacatgac gggccttttc agcattttct
    33061 cgaaaattat gatactggat atccaagagc cctttttctc gagcctttcc aacgattgag
    33121 tgctccagtg gagaaaacat ctctggaaag agggttaaaa tatcaatctt catcgtctaa
    33181 cccttctaag atttccacat cgacccgttt atttggaata tcaacattga gaaccactgg
    33241 tgggatataa ggtaaaagca aatcacgttt gccttttcgt ttgaccaccc agacatcatt
    33301 agcacctggt tgcaggattt ccttgatggt tccaaccaag ctatcaccct catagacttc
    33361 caaaccgata atctcgtgat agtaaaattc accatcgtct aggtcattca aatcttcctc
    33421 agcgaccttg agactgtatc ccttgtactt ttcgatagta ttgatatggt acatatcttt
    33481 gaatttaata atgtcaaagt tcttctgttt acggtggcta gcgatggtca ctgtttggac
    33541 aaactgatct ttttcatcaa acaaagccag ctcagctcct tttttaaacc gttcttctgc
    33601 aaaatccgtc acagacaaga ctcgcatctc accctgtaat ccctgcgtat taacgatttt
    33661 cccaacatta aagtagttca tcttgtctcc tgtaatctcc ttttttccat cttattctga
    33721 caattctcga ataatagccg caattttttc cgattctgac cattgtaaat aatggtgatt
    33781 ccttcctaaa atgagtttag tattggaagt ccaatattct gattctctgt actctttttc
    33841 tctataagtc tgacaaaaaa taaatacagg gacatgagat tctatcgaca aattctcaaa
    33901 atcttcctca gtaatctctc cagatatctg aaattctgga tcttgatttt ccaactctaa
    33961 gcctttttct tgcattaatt cccagatttt tttattcgtt tcaggactaa atgttgcttg
    34021 agttaagttc ttaaaataaa gttcaggacc acactcgtca atcagcctca tctactcttc
    34081 catttctgga taaggatttt ctgaaaaatc agcaaacatg acttttttag ttgtcggttc
    34141 aattgctact aaagtctgac gcttaattgg tttctcgagt aatttgcaag ctaaaattcc
    34201 actccaacta tgtgcacaaa gtatatattc agaaattcct aattcttcaa gtacttcata
    34261 aaccgcatct gcaagattat ctagtttttt tccagcttgg tcatgaatcg gactcctacc
    34321 tgtgttcgga aaatcaattg tcaaataacc aattgtagga ggaggttttt caagtataag
    34381 tgaaaaattt tcataacttg gtagcaaacc tgctccgttt agacaaacta gcactttctt
    34441 ttgcttttga taagtaacag agaggctacc aatttctgta gatacttcaa acctcttcat
    34501 aaagaaatcc actcattcta tataatgaat tattaaaaat cattatcctt tattttatca
    34561 cgttccaagg attttctcaa gttggaggaa ggggacaaca tctctacttt cccttcaaga
    34621 atccttccaa attatgttta tgttggtaat taacggctgc ggttttgtct ttctcaaaga
    34681 cagtcttggt aaggtcaata tgattaatag ctacgattgc gacggtgtag taaatgatat
    34741 cagccagttc tctggcaagt tcctcgttcg aatcctatcc cttcttttcg accagagcgc
    34801 ctattcaaaa cctcggctac ttctccgact tcctccacta acttcataaa gagaccttca
    34861 tcagtccgag actgctgtta atgttcgatt aagtagtctt ggaattgcct aaacgttcaa
    34921 tcttttatag tatattgaaa ctagaatagt acacctttac ttctaaaaca ttgttagaaa
    34981 tcgatttgac tgtcctgatc gatttgtcct gttcttgttt cattttacta tatcttctat
    35041 tccacacaaa aaagcgagac atccgtcccg cccttcttat ttttcgtcaa taacgattct
    35101 tacttttttg tattcagttg ggacagagta gacaatcgtt cttatcgcag aaatagtgcg
    35161 acccttacga ccgattacac gacccacatc gctttgatca agattcaaat gatattccaa
    35221 aaattctggt gtatcctcaa tcttgatagt taaggcatct ggttgtgaaa ttaagggttt
    35281 cacaatcgca ataatgagat tttcaatcgt atccatctgt caacctactt taaacttatt
    35341 ttgaaaattt agaatcgtgg aattttttca atacgccttc ttttgaaagg atgttacgta
    35401 ctgtgtctga aggttgagct ccattagcca accatgcaag aacgcggtct tctttcaaag
    35461 ttacttggtt ttcagcaaca agtgggttgt aagttccaac tgtttcgatg aaacgtccgt
    35521 cacgtggtga acgtgaatct gctacgttga tacggtagaa aggttttttc ttagaaccca
    35581 tacgagtcaa acggatttta actgccattt ttaaagtctc atttctttaa ttttttattt
    35641 cggtgaaata gctgagctat ttagcacatg ttctattata gcagatttct ggcatgtgtc
    35701 aagaaaaaaa cttgacagac tataaatttc ttaaagtatt tagaaatttg ttagaatagg
    35761 aaataaatgt ttgaaagatg ctatccgtga atactatttt agaaaaattt tataaagaac
    35821 accaagtcaa acccttcata tcgcctgaac gagagttgga tacttggctt ctaagtccca
    35881 agcccgttcc caagcgaaat atggacttat tagtagatga ttcactagca ggagatatca
    35941 ttttactatg gagaatccag tttggtactt ttaccactga aacatgattt taaaaactcc
    36001 cattcgaata tgattcaaaa ttcgcttaga atcaatgttt tcccactttt tcaaaaaata
    36061 aattttcatc taatttaaat aactttcaat taagtgtgaa ttttgcttaa aatcattaaa
    36121 aaacacccca tggtgtgaac catgaagtgt tgtaaatgct gtgttgtagc tagttcttag
    36181 cgtttagaga actggctagc tttacgagct ttcttaagat ctggtttcca aaatactttg
    36241 agtacactta tggtattgat gcccctaaac atctaaaaac tctggtagaa aaagggtatg
    36301 ctcttgtcga aacttctttt gactcacttg accatctaaa taataccatg aaaaagaata
    36361 tcctgaagaa gaagggagtt actggacttt ctaaaatgaa atcttgcgac ctggatcaag
    36421 cccttcatga gcatttttca gaagaagaat tagctggtca ctttcatgtc cttctatgga
    36481 cttttttaca atggcattgc tatcacaccc aatacctatc taagcgcctg gttcgtaaac
    36541 tttattgcag ctcttcctct aaatttccta attgttgaac caattgctcg ttttatacta
    36601 agttcttttc agaaaccatt tactggggaa gaagttgaag attttcaaga tgatgatgaa
    36661 atcccaacta ttatctaagc cagttctgta aactactaat atttgaaatc cacttccttt
    36721 tagggtacaa tggttataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
    36781 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
    36841 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
    36901 ctgccaagga gttaaacgat gcattaacaa acgaaaacgc caatttccca caactatcta
    36961 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
    37021 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact catgccaaag
    37081 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
    37141 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
    37201 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgcggtg
    37261 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
    37321 aaaactctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
    37381 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
    37441 tgattggcgg tatggatgtt gtggataaga ttgctaaagc cgaaaaagat gaaaaagaca
    37501 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
    37561 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
    37621 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
    37681 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
    37741 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
    37801 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
    37861 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
    37921 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
    37981 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
    38041 cgagataatg cctaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
    38101 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggacggtc
    38161 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
    38221 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
    38281 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
    38341 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
    38401 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
    38461 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
    38521 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
    38581 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
    38641 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
    38701 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
    38761 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
    38821 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
    38881 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
    38941 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
    39001 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
    39061 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
    39121 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
    39181 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
    39241 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
    39301 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
    39361 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
    39421 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
    39481 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
    39541 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
    39601 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
    39661 tgcgactgcc ttctggcggt cacgtttcat tgtgttagag cgcaattgtc cacaagctgc
    39721 gtcaatatct gtaccatgct cttgacgaac cacacagttg accccttttt tcttaagcgt
    39781 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
    39841 tgggttataa ggaatcaagt ttacataaga caatttcttg atgttcttga gcaattcagt
    39901 caattccaag gcttgttcta caccgtcgtt gacttcatta agcatgatat attcaaaggt
    39961 tacaccacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tttcaatcgg
    40021 aaaggcacgg ttaatcttca tgatacttga acgaagttca ttgttaggtg cgtgaagaga
    40081 cacggcaaga ttgacctgaa ccccttcatc agcaaagtca cgaattttat gagccaaacc
    40141 tgaggttgaa accgtgatgt gacgagcacc gatagccatt cctttatcat cattgatagt
    40201 acgaaagaaa ttcaagacat tgttgtaatt atcaaagggc tcaccgattc ccatgacaac
    40261 gatatggctg acgcgttcat cctgaccacg ctcagcaaag tatttctgaa ccagcatgat
    40321 ttgcgctacg atttcaccgt tattgaggtc acgttgcttc ttaatcaaac cagaggcaca
    40381 gaaggtacaa ccgatattac agccgacctg agtggtcaca cagacagata aaccatagtg
    40441 ttgacgcatg agtacagtct caattaacat accgtcgggc aattcaaaga gatatttgac
    40501 tgtaccatca gcagactctt gcacaatacg ttgtttcaag ggattgacca caaactggtc
    40561 attgagctta gcaatcaaat ccttggaaag gttggtcatt tcttcaaatg actgcacacg
    40621 tttacggtag agccattccc agatttgatc tgcacggaat ttcttttctc cctgctccaa
    40681 tacccattcc tgcatggttt gatgtgccaa actatgaatt gagggtttca tttcttctcc
    40741 ttattctcta ctcacttctg acgaatgaca aaatgacgtt gtcccttgtc ctctttctga
    40801 gaatgctggt ctttctgacg acgtctattt ttcttatctg cattcgactt tcgtttagtt
    40861 tgagtcggtt tctttccttt tctagaaggt gtttcttctt ccgtcttacg cattttcttg
    40921 tcaaatgatg ctcgcttagg ggcttcattt tctaagacaa aataggcaca accataacta
    40981 caatactcta aaaggtagtc ttgtaaacga ctgatttttt caagtttttc ttctgttcgg
    41041 tcatccttgt aaaaacctcg taggcgaagc tgttcgttgc tccagtcccc cacgatataa
    41101 tcaaacttgg ttaatacttc tgaaaaacgc tgattaaaag tcgtcacatc aaaggcatcc
    41161 ttgatatttt caaccaagga aaaagctatc ccttccgttt cgaccttgtc cccgtgtaaa
    41221 tggaactccg gaccaggaaa cttgttatag ttgtataatt caggtgcaat ttcttttcgc
    41281 atagatatcc ttttttcacg attacttaat actttattct accataattt ctagcagtta
    41341 gcacgtttct cataaaaatg aaaaaagtct gacgattttg tcagaccaga atcttataac
    41401 ctaaaaagag aagaacaatt cttccctcca actatcatta tttagcagct gcgtacaatt
    41461 catctacttt attccagttg attactgaaa agaaagcttt gatgtagtca ggacgcacgt
    41521 tgcggtattt cacgtagtaa gcatgttccc aaacgtccaa gcccaagatt ggttttttac
    41581 cttctgagat tggtgtgtct tggtttgctg ttgaagtcac ttcaagtttc ccttctttgt
    41641 tgacaaccaa ccatgcccaa cctgaaccaa aacgagttgt tgctgctgca gtgaaggctg
    41701 cttggaattc ttcaaatgaa ccaaatgttg catcgattgc tgctgccagt tctgctgaag
    41761 gagctgtttt ctcgggagtc atcaattccc agaaaagagc gtggttcaag tgtccgccac
    41821 cattgttgat aagtgcttga cggatatcag ctgggataga ttctacatca gcaagcaagg
    41881 cttcaaggtc ttcaccgatt tcagggtgtt tttctaaagc tgcattggca ttgttgacat
    41941 aagtttgatg gtgtttgtca tggtgcaaat gcattgtttc cgcatcgatg tatggttcca
    42001 aagcgtcgta tgcatatgga agttctggta agataatagc catctgtaat acctcttttt
    42061 ctttctatat gaaaatgata acgcaaacat tcactttttt caagtttttt gcttatagat
    42121 aaggaaatca ctgacatact ttctaataaa ataagcaaat cagcaagaaa cccacgacaa
    42181 gatagtcctg acgcgggttg tagtttcaac aaatgtcaat tgacctgact agcaatctgt
    42241 aagagtgcct tttcaaaaag gaaacctttt tcataaagac ctgtcttaat ctgatagtct
    42301 gtctcaatca aataggaaat agcttgcttc aaaaagctca aagaaagtcc tctcgaatct
    42361 cttaatgcaa acttgatttg ataaggattt gggttacgtc ccagataact acctaaacta
    42421 cttgcaatct gcgattctgt ttggccagac tccgccaaaa tcttcacctg agtaaaagtc
    42481 cgaaattgtc ccagcatgac tgcaatcagt ttgatttcat cttccccttg caaggtcaag
    42541 tctctcacca aatcgcgcgc ctgatccatc tttttagtca gaataaactg agttaaatca
    42601 aaaatattgt cctgcaaggt cttgggaatt gcgttaacaa tatcctcttc ctcaataaca
    42661 gaattcgcct tataggactg taaaaagaga agatttttct ggatttcgct aaattgaaac
    42721 cccgacttga tgaggagatt ttcaaaagaa tgattggtaa actgcagacc ttgtttctga
    42781 ctccactttt ggaaatactg gcgcaattct tgttctttta cttctactgc atcgaagacc
    42841 ttggcatcac gcttaagtaa tttgactaac cgtcttttgc tatccagctt tccttctgca
    42901 aagattatca acttggttgt tggagaagaa ttgtcaaggt attcctcaaa tgacttaagc
    42961 tcatcatctg tcaaaaagcg tttcttagca gtcgtgatat ccataaaata atctaatatc
    43021 acgattttct catccgcaaa gaaaggaagg ctgaccaact ccagttccac atccttgtaa
    43081 actacttctt tcatatcaaa gtaggcaaag ttgaggtcag cagaatcata cccaatctgt
    43141 ttcaacactt gactcttcat cacttcaaac tgaccctgat ctgtccctgt aaataggctc
    43201 aggctcggta aatttgataa agtcaacttc tgactttctt caatggctag catcgtctct
    43261 cctttcttca gatttttcga tttaatttag tcaatatagc gcaatttccc acggaaatct
    43321 tctaagctct cgtagccttt ttccaccatg attgctttca gttcattggt aatgcggtca
    43381 aaagcactga cgccttcttt gtgaagggtc gttcccacct gcaccatact tgctccacag
    43441 aggatgtgtt caaaggcatc tcgaccagtc agaacgccac ctgttccgat aatttggatt
    43501 tgaggattta aacgttgata aaaggcgtga acattggcta gagcagtcgg tttgatgtat
    43561 tctccaccaa ttccaccaaa accattctta ggccgaataa cgacagattc gtcttctata
    43621 tagaggccgt ttccgataga gttaacgcag ttgacaaact tgagcggata tttgttgaaa
    43681 atagctgccg cttgatcaaa gtgaacaata tcaaaataag gtggcaattt aattccaaga
    43741 ggtttggtga agtaagcaaa cacttctgcc aaaatccggt ctgttgtctc aaaatcatag
    43801 gcaatctgag gtttacctgg aacatttgga caggaaagat ttagctcagt cagaccacga
    43861 aaatcactct cttggacttt tttcaaaata gtatgggttt cctctggaga catgccgacc
    43921 agagataaga agaaagttcg gttcgactct ttttcctgca aatctaaaag ataatccaaa
    43981 taatagtcta agccattatt tggcaagccc atagagttga tggaaccaag tggaacatct
    44041 tggtagcgtg gctcaggatt cccctgacgg aagtccaagg tcgctgtctt agtaacaaag
    44101 gttcctgccg ctgagttttt gacctcttct aactcctcta tcgtcataca agccacacct
    44161 gctgcattca tcaagcaatt gtcaaactca aaaccagcaa tttgtgtttt cgttgatacc
    44221 atgattctaa tcctccagat ttcttttatt gctaatatta taccataatt ttaattctag
    44281 gtttactaga ttctgtggtt ctatctattt attcggaaaa gaaagtctag tacagaagtc
    44341 atgctatgga aacagctagt gtattagaag tttgaacaag gcttgggtaa cagacttttg
    44401 aatgaagtcc aagcaacaag gagaaatctc aaccatgagt ccattccatg actctgttgc
    44461 tctagaaaac cttgcaatag tcaagtgata acgaataaaa ctttggattg aaatatcccc
    44521 aagattatct attacgagga gaaatcttaa cctttatcat ttttaaagaa atatagtaaa
    44581 atgaaacaag aacaggagaa atcgatcagg acagtcaaat tgattgctaa caatgtttta
    44641 gaagttgagg tgtactattc tagtttcaat ctactataca tgtaaatctc tactttcgca
    44701 aaatggattt tcagaacagt atcccagtat agttaaaaac tataaaaaag agaggacgtt
    44761 cccctcttaa aatcttattt tactgcttct ttcaaagcat ctaccttatc caaacgttcc
    44821 catggaagat caatatctgt acgtcccatg tgaccgtaag ccgatgtttg acggtaaatt
    44881 ggacgcttga ggtccagcat ttggataatc cctgcagggc gaaggtcaaa gatttgacga
    44941 gccgcttttt caagttgact ttcagctact gttcctgtac cgaaagtatc gatacgaaca
    45001 gaaacaggtt gcgcaacacc gatagcatag gccaactgca cttctgcctt cttagcaagg
    45061 cctgctgcaa cgatattctt ggcaatatag cgagccgcat aagaggctga acgatccacc
    45121 ttagtcgcat ctttaccaga gaaggcacca ccaccatgac gagagtagcc accataagta
    45181 tctacaataa tcttacgacc agtcaaacct gagtcccctt gaggaccacc gattacaaaa
    45241 cgacctgtcg gattgataaa gaattttgtc ttatcatcaa gataagaaga tggaataact
    45301 tctttgatga ccttgtcaat cacatcttga tggatttgtt cattagtggc ctctggatca
    45361 tgctgagtag aaataacgac tgtatctaca cgtaccggac ggtcattttc atcgtactca
    45421 actgtaactt gtgattttgc atctggacgg agatagctaa tttctccaga cttacgaagt
    45481 tctgccagac gacgaaccaa tttatgactg agtgcaattg gcaatggcat aagctcttct
    45541 gtttcatcta ctgcaaatcc aaacatgagc ccttggtcac ctgctccaat caagtccagt
    45601 ggatcttgat cagcatttcc acgaacctcc aaggcttcgt taacaccttg agcgatgtca
    45661 ggagattgtt ccaccaaaga tgggtgtact cccaccgtct cagcagaaaa tccatattct
    45721 gtattggtat aaccaatctc tgcaatggta tcacgaacca cacggttaat atccacatag
    45781 gcatttgtag aaatttcacc aaaaacgtgg acagaaccag tatatacagc tgtttcagca
    45841 gcaacgtgcg cctctggatc ctttgctaaa atagcatcca aaatcgcatc tgaaatttgg
    45901 tctgcaatct tatccggatg cccctcagat acagattcag acgtgaataa tttacgctct
    45961 gacataaaaa tgtcccccct taaaaaatat tgttatagag ttacaaagta ctgataggaa
    46021 aactcttcgt aataaatacc taccatctta tcgggactat ataactttat cattatacca
    46081 tttttaatcg caatttgcag tctttaatgt agtatttcgg tttagatagt tcgttctcat
    46141 aaagcaaaaa gttggagctc agtactccaa caatttctat taaaatgttt gacgtttagc
    46201 tttacgctct gcacgaccgc gagcgcgatt ttcagcacgc ttggttttac ggcgcttttc
    46261 atcaaccgcc cattgaattt tcttcttata acccggtttg acttttttct ttttcttttt
    46321 aaccaaacca atcatttcga tatcaagttt atcttgtttt ttctcacggt tggcacgacg
    46381 atcacggtca taggtatctt gaaattcccc gtctttgacc atcttaggac taaacttgat
    46441 tcccaatttc tccaactcac ggatatccga gtcatcactt ggctgataaa gggtaatagc
    46501 tgtacctggt aggccatttc gtccagtacg accaacacgg tgaacaaaaa aagataagtc
    46561 ttgcggaatg gcatcattga tgacatggct gacaccttca atgtcaatcc cacgtgctgc
    46621 caaatctgtt gcgacaatat actcaaaatc cagattttgc acctgattca tgattcgctt
    46681 gcgttcacga ggggcaatat cgccatggat ttttgcaacc ttcaagcctt gagcagtcag
    46741 atatgaatgc aattcatcag cacgcgtttt agtgttaaca aaaatcattg ccaaatacgg
    46801 ctgcatcaac tgagtcaact ggtaaatttg agcattctta tcatgtccct tggtcgaaat
    46861 caaccaatta tcaatggtgt cagaaataac cgttttggtc ttaattttct ccataacagg
    46921 atttgataag tattttttca agaatggttg cagtttttgt gggatagtcg ctgagaagac
    46981 catgaattgc aagtcttttg gaagactgcc agcaatctta tcaacagttt ccaagaatcc
    47041 catatccaag gtcatatctg cttcatcaac aacaaatgtc ttggctttat gaatagctaa
    47101 atcaccagat ttaaccaagt cgtagatacg gcctggtgtt ccaataacaa tatgaggctg
    47161 attgcttgcc aatttctcaa tctggcgagc cttatccgta ccacccacat aattaaccac
    47221 acgaacttcg acatctgagt gagctgaaat ctgacgcgct acttggtaaa tttgagtagc
    47281 caactcacga ctcggtgcag taatcactgc ttgcacacta tcgctagctt catctaattg
    47341 ctggaaaatc ggtaacaaga aagtatgagt cttacctgaa cctgtttttg attctcctac
    47401 taggtcacga cctgccaaaa caataggaat caacttgtct tgcacctctg ttggagttgt
    47461 aaattttaac tccttcaagg cttctctaat atagttttta aattgaaatt tcgtaaatga
    47521 cataacatcc tcgattctat ctatcttatc aattatacca tattttattc cattacagta
    47581 gtctcactta tttaggctat ttccagtagc ttctctagta agaaaaggct ggaattttat
    47641 agttccaacc tcttttcagt tattatttcc agtttaacat agcattcaag ccatagtgat
    47701 cactcacttg tggactcttg ttaccatcaa atacgacatg taaattttcc accgctaact
    47761 ctttggtagt aaagacataa tcgattcgaa ggggttcagt gttccctttc cagccatcaa
    47821 tttcaggcgg aacagtatag ctaccacttt tctcttgagc aacttcaaat gcgtcttgta
    47881 agtctaatgg actagctaaa atagcttggt aaccttcctg acctgctggg ttgttaaaat
    47941 ctccagctag taaaagtggc ttgttcaatt ttttcaagac agcctcaaat cgtgcccatt
    48001 cttcttggaa acctttatcc caccaagaga gatgaacact ggcaactgct agctccttgc
    48061 catcgactac agtttcagct agggcaacac ggcgagtatg atagtctgtt ggatcatcca
    48121 catctgaaac caaaatttct ctggcttcaa taggtgtttt agacaagata gccacacctt
    48181 cgtggtagcg gtcatagccg atatggttat aagcccaggt ccagtagtaa tttttccctt
    48241 gctctaacaa cttttcaacc aagagtctaa cataatggtc ttggtgaata ggctcagctg
    48301 ctggcaaagc ttgataaagg tcattaacct ccacctctga cgaggtcatc tcctgattga
    48361 tttcttgaaa acaaatcaaa tcatagtcct tttcaagaat atcttcaagc aaaatctgga
    48421 atttttcctc tgcttctttc tccatccaac tgtgagtatt gagtgttaaa aatttcattc
    48481 ttttctccca aaataagagg ttggaataca gcttccaacc tcaagtatat tacaattcta
    48541 ctttagcaac tgctgtttta gctgcaagag aacctgtttt ttctaactta actgatttaa
    48601 ttgcatcacc atttgtgaag acaactactg ttgaagtttc acgtcctgct gcacggatag
    48661 catccaagtc agctgtgaca aggagatctc ctgctgcaac tttttgtcct tcagcaacat
    48721 gaactgtaaa tggtttacct tcaagactta ctgtgtccaa accaatgtga accaatactt
    48781 caagacctgc ttccgtcaca ataccaaaag catgttttgt tgggaagatg cttgacacag
    48841 tacctgaaac tggagataca atgtttccat ttgcaggttc tactgcaaat ccatcaccca
    48901 tcattttttg agcaaatact ggatccttta cttgttccaa accaacaact tgaccgtctg
    48961 ctactgaata aacttcctca gtaagatctt tgaagtgaac agtgttttgt tgtgcttcag
    49021 tcatttggct tggaagagtt tcaggaatga tttcacctga atcaaggata tcttggatat
    49081 cagatttcaa tatgtcagct tttggaccgt agatagcttg aaccccttgt cctttcatca
    49141 caagacccat agctccttct gctttccatt gctctgcatt tcctacttta tctgcatctt
    49201 taacagttac acgaagacga gtcatacatg catcaacatc aacgatgttt acacgtccac
    49261 caagaaggtt gataatgttt acagcttgag aacctgctgc aactttcact tcgctgctgg
    49321 tttcttctga accttcagca gtttcgtagt ttccgttgcg ccctggagtt gcgtagttga
    49381 atttttgaat catgaagttt gcgataaagt acatgattac agcaaagaga acagttaccc
    49441 aaacgaagtt aacgatatcc ataccaatac cagcactgat tacaataggt gtacgagtca
    49501 agaactcgat tgaaccgaat gagtgcatac gtaggtttac gacgtcagcc atagcgaagg
    49561 cagcaccttg aacaagtgag taaacaagat acataggtgt tgcgatgaac atgaacatgt
    49621 attcgattgg ttcagtaacc cctgtcaaga atgttgcaag agctgttgca atcatcatac
    49681 ctttgtattt atgtttcttg tcaacatcaa cattacggta gatagcaaca atcacaccca
    49741 tcaagatacc gaatgaaccg atcatttgtc caactttgaa acgagctgga tgtactgtat
    49801 ctaacaagtg ttggtattga ctagcatcag tacctttaag gtttacaagg tctgttaccc
    49861 atgcaagcca tagtgggtct tgaccgaata cttgagtacc tttagctgca ccagttaaaa
    49921 tgtcataagt accaccaaga gctgtgtagt tcattgggat agtcaacatg tggtgaagac
    49981 caaatggcaa gagcaaacgt tccaaagtac catacaagaa tggtgcaaga attggagcag
    50041 tttcttgtga gttggcaatc cagataccga aattattgat acctgtttga actactggcc
    50101 agaaagcagc aagtagaatt gcagcgattg ctgaacgaag aataactaca aatggtacga
    50161 aacgtttccc gttgaagaat gaaagtgcat caggaagttt acggaagttg tagtatttgt
    50221 tgtaagcagt tgcccctaca aaacctgaga taatccctac gaataccccc atgttcaagg
    50281 ctggagcttc aagaacactg ataaagtaat cagcaacttt gattgaacca ccaaagaaag
    50341 tagttaccat agcatctgga tttttcaaca tatcgcctga tacaccaaag attgtaccag
    50401 tgatacggtt aatcaagatg aaggcaagac cagcggcgaa agcaccacca gcacgttctt
    50461 tagcccagct tcctccaatg gctagggcaa acaaaatgtg aaggttaccg ataacccccc
    50521 aaccgatttg ctcaagaatt ccacctgtga tgacaagtgg tgcaaaggtt gggttaatca
    50581 tcacgataga cttaccgatt gaaatcatca aaccagcagc cggcataacc gcgataacta
    50641 ccatcaaagc cttaccgaat ttttgccaaa attcgaaaga caagacattt ttgaatgtat
    50701 ctttcatcat tcaaatctcc tttattttta tttaggcaaa cgttttacga aaacgtttgc
    50761 actttctatg atttaattat accactttaa ttttttttgt aaaggctttt ataaaaaaat
    50821 tacacttttt tctaaaaaat ttctagcgcg ccaaatttca agttcaaatt agccatcaag
    50881 aagtcttctc tgggggactt ctttggaagc tcttttcttc tgcgcatctc ttttcaaaaa
    50941 ctcttgtagc aaaaaaggag attttacaat ctcctcataa aagcagctat tttacctaaa
    51001 tcttcaagaa tcggcgcatg gatattcctg atcccaatga accaatgaaa accccaatca
    51061 caaatagtag ggcaatcatc aacggactaa ataaatctgg actaatcatg gatagatttt
    51121 gccctaccaa cgatttgttg acagattggt aaacaatttg ataaacaata aagaccaaaa
    51181 cagatggtgc gatagctccc aataaaccga taaaggctcc ttctaacaag aacggtccac
    51241 ggatataact gtttttagct ccgaccaagc gcatgatttg aatttcgcga ctgcgggaaa
    51301 taatggtaat acgaatggta tttgaaatca agaaaactgc gataaaaatt aacaaagcgg
    51361 caatccctag tccccaaaca cggataaatg aagctaactt gaagagtctt tctgtattgg
    51421 caccgccatc ttgaacctca gagacacctt caattttttt agcatcttcg gctatagttt
    51481 ttacatcatt tggagtgttt gcctctacaa tataggcatc atagagagga ttggcatctc
    51541 cttcaaagat tttccagtta tctcccatta tctcggttaa tttttcatat tgttcttctt
    51601 tacttgaaaa ggtaacactt ttaaccgtag acatgttctt caaagaatca tataccttgt
    51661 ggtagtcatt atttgtaaca gtttgacctt ctttttcaat tgtctgacta ttatcttcca
    51721 catcctttcg gatataaact actacacgga cattattttc aatatctgta gctagtttcg
    51781 ctgtattgaa aataacagat gcaaatattg ccaccaaggt caaagtaatc atgactgaac
    51841 tgacagcagc tactgtcatc caaccatttc gtttcaaact ttttaaggct tcaaataaat
    51901 ggcgaaaaaa tctactaatc atcgtatcca tactctcctt ttgattcgtc acgaacgaca
    51961 cggccatttt caatggcaat gacacggtgg cgcaaggtat ttacaatctg gctattatga
    52021 gtcgccatca aaatagttgt tccttgtagg ttaatccgtt ccaagagatt cataatttcc
    52081 catgaattat ccggatccag atttcctgtt ggctcatcag ctatcaatac tttgggatta
    52141 tttacaattg cacgcgcaat cgcaatccgc tgttgctccc cacctgagag ttcatttggg
    52201 aaagaacgaa ccttatgctt caatccaacc aagtccaaaa cttccatcac tcgtcttttg
    52261 atattacggc gattttcccc gattacttcc atagcgtaag caatattttc atagacagtt
    52321 ttctttggta acaatttata atcctggaag acaaccccaa cactacgacg tagaagcggg
    52381 atatctttct ttttgatctt aaccagatta aaaccagcaa ctgataggct tcctttatcg
    52441 atttttactt cacgatacag agaacgaata aaagttgact tccctgctcc tgaaggtcct
    52501 acgatgtaag caaattcccc cggttgaacg ctaaccgaaa caccgcgtag agcagttgtt
    52561 ccgttgtcgt attttttaac gacatctctc atttcaataa ttgacatgtg agttcctttc
    52621 tatcttagct aattcgccac ttgagataag catcgataaa accatctagg tccccatcca
    52681 taaccttatc tacctgagca acctcaaagc tagttcggtg atcttttacc atagtataag
    52741 gcgtgaagac ataagaacgg atttggcttc cccaagtgat ctcttttttc ttacctttga
    52801 gagaatctac ctccgcagcc ttcttatctt gctccatttg atagagctta gcctgcaaca
    52861 tcttcatggc acgatctcta tttccatact gggtacgatc cactgttgat tggacaacaa
    52921 ttccagttgg aatgtgggtt aaacgtacac ctgttgaaac tttattgacg ttttgtccac
    52981 cggcaccacc tgaacggaag gtatccatct tgatatcatc ttcacggatt tccacttcaa
    53041 tagtatcatc caattctggc atcacttcta cagatgtgaa agaggtatgg cgacgtttgg
    53101 cagagtcaaa tggtgagatt cgcactaagc gatgaacacc catttctgac ttgaggagac
    53161 cataggcatt aggcccttca aatgataaaa ttaccgactt aataccagcc tcatcacctg
    53221 cttggtaatc caacacttcc actttaaagc ctttagcatt accataacga gtatacatac
    53281 gaagcaacat atcaccccag tcctgcgcct cagtaccacc agaacctgga tggatttcca
    53341 agatggcatt gttgtggtca taaggttctg acaagagtag agtcatctcg tagctggtca
    53401 ttatcttatc aagttcggct aactgcgcta ccagttcatc atgcactgac tcgtcttcag
    53461 ccaaaaaatc caataaaatt tcgacttcat cctgcaactc ttccatctta tggaaggtat
    53521 tgtaagtgtt ttttaattca ttcaattctt gcgacgtttt ttgggccgca atattatcgt
    53581 tccaaaaatc aggttctgtc atcttgtttt ccaagatggc aatctcttcc tctagccctt
    53641 cgaggtcaaa gagaccccct gaaagaagct aatttttcac gatttgcgtc aattttctga
    53701 cgaattactg aaatgtccat aaatactcct tttttacatt atttcattat agcatatttt
    53761 atcatttctt tccatctttt gctctaatcc ccttttcatg aaaaaagaag cctttgggct
    53821 tcccttctta caagactttt gctgaagtgc gagcgatttc ttccacttga ataccatttg
    53881 cttcaaattt ttctttcaag gctggtaaat caattgatcc atcgatttgc acttcgataa
    53941 tcaccttacc atccttacgc ggaatattga ctgtatggga gatattcaaa ttttcttcta
    54001 caatcaaaga aacaattttt ccaagaacac caacttcatc ttctgtaaca aagcgtacac
    54061 gaatcccttc ttcgccataa cctgcaattt caagaaaggc ttggaaaaca tcacggtcag
    54121 taataactcc gtatacttga tggttatcta cgacagggag aataccaatc ttatttttca
    54181 acatcagata agttgcatct tctagactag catagcctga gacagtgaca acatcgcgaa
    54241 tcatgacatc ttttactttt gtcttattca gaagataatt catctcatag atagaaagac
    54301 ttgttgcttt agatggactt gcttgtgcaa tggttccctc agtcaccaaa ccaaccaatt
    54361 gatcattttc gataacaggc aagcggtgca attcttgctc tctcatcaaa tctgctgcat
    54421 gagatactgt tgtatctgga ctaatataaa ctaccttgcg ggtcataaaa tctttaactg
    54481 ccatgagact tctccttttc tattcttatc cctattatac aatctttttg caaatctatc
    54541 aaacgcttac atttcttttt caaaatttag aaaagtatga ataagctagc aaaaagagct
    54601 ctaaaatcga gctctgtgaa tgaaggtaag aaacttttca ttcgattttt tcaattatta
    54661 gaaattaagc tttcaatgta gatgcagatt tgtttgcaat ctcaatctac cgactaaaaa
    54721 ggtcccccgg actatattga tgattacttc gtaatctcca tctgccgact aaaacaatcc
    54781 actggattgt tttagccacc tagatatgct tttctgactt cttctgatga agcgagttct
    54841 tttcctgttc ctgataggac gattttccct gtttccagta catatcctcg gtcagagatt
    54901 gcaagtgctt tattggcatt ttgttcaatc aagaggacgg ttgttccttg tttctgaata
    54961 tcttgaatga tatcaaaaat ttcttggata aagattgggg caagtcccat tgatggttca
    55021 tctaaaagaa gaagttttgg tgttgacatg agggcgcgtc ccatggcaag catttgttgt
    55081 tccccccctg aaagagtggc tgcatcttgg ttcttccgtt cttcaagacg aggaaagcgt
    55141 gagaaaacct tcttcaagtt agcttgattt tcttcacgat ttttctttaa gaaagctccc
    55201 atttcaagat tttccataac agtcaagcca ggaaagacgt ggcgtccttc tggaacttgt
    55261 gaaagaccac ctgccacgat tttctgagct ggcatttttt ggatttcttg acctaaaaat
    55321 tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg tgcgaagaat agttgtctta
    55381 cctgcaccgt tagcaccgat aagggaaaca acttctcctt cattaacttc aaagcttaca
    55441 tcacggactg cttggatcat accgtaatgc acagaaagat tttcaacttt taacatagac
    55501 attaggcttc acctcctaga taagcttcga taacgcgttt attggtctta atttcgtctg
    55561 gagttccttg agcgattaaa cggccatatt caagtacgta gatacgttct gttacttcca
    55621 tgaccagatt catatcgtgt tcaatcaaca tgattgtaat cttaaactca tctttgatac
    55681 gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt catacctgct gctggttcat
    55741 ctaagaagag aattttaggt tccgtagcaa gggcacgaac aatttccaaa cgacgttgtt
    55801 gtccgtagga aagattttta gcaagagtct ctgcatcacc atctaaatca aagattttca
    55861 acaattccaa agctttagcc tttaattctt tttcactctt gtaaaaagct ggtaagcgta
    55921 agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa agcaatcaaa acattgtcta
    55981 aaactgttaa atctttaaaa agacggatat tttggaaagt acgtccaagt cccaaagagg
    56041 caatcttata aggtgatttc ccattcaaaa ggtgaccatc tagggttact gttccctcgc
    56101 ttggttcata aacaccggtc aaaaggttga aaagggtggt tttcccagct ccgtttggac
    56161 cgattaatcc aaccagttcc ccttcgttca attcaagagt cacatctcca acagctgtta
    56221 gaccaccaaa atgtttggtt aactgtttta cttcaagtaa tgccattagt tttgttcctc
    56281 cttcttagat tttttaaaga aacgtgatag gctcagttcc cacgttccaa ggagtccacc
    56341 tggtctgaaa atcattacca ataccaaggc taaagcgtaa ataatcatac gcacactagc
    56401 aacatcttgg agaagcatat tcaaaattcc cagaacaata gccgaaacaa tcgcacctgt
    56461 aatggaaccg agtccaccaa atacaacaat aatcaaaacg ttgattgagt taatgaaggt
    56521 gtaatctttc ggtacaacag acccgataaa tcctgcctga agtgacccag caatacttgc
    56581 agtaatggca ccaaagacaa aagcgatgat tttaatttta gtcgtattaa ccccaactga
    56641 ctcagcagcg atttcatctt cacgaacaga gagggttgaa cggccaattg ggctacgcaa
    56701 gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag taaaccattt gccaagttgt
    56761 aaagttagga atccctaaga tacctgccgc accatttgta agacttccac cattgatgat
    56821 aaagatacgg ataatttcag aaacacctag agttgctacc gcaagatagt cccccttcaa
    56881 gcgcaaggtt ggaatgccga caagtaaggc aactgctcct gaaagcaaag cccctacaag
    56941 catagctcca aagaaggcac cgtaggttgg taatttagaa ccaataatag ctgctgcata
    57001 ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat tgtcctgaaa aaccaacgat
    57061 taagttgaga ccaacagcca aaataatatt aattccaatt tgttgtaaaa tctgtacata
    57121 gaatagatta agtactccga ctgaaaccag tacactaatc aagctatagc cagctaacaa
    57181 aaggagtaac catagaatat taacttttaa attttccttc atcgtttaca ccttctcttt
    57241 cacattctta ccaaggatac cagctgggcg gacaatcaag atcaacaaca agattccata
    57301 aacaatggca tcacggaaat ctgacatccc aaaggcagtc gcaaaggttt ccaatagacc
    57361 aatcacaaag ccaccaagag ccgcaccagg aataattccg ataccaccaa gtactgcggc
    57421 aacgaaagat ttaagacctg gagtaacccc catcaaaggc tcaagagagt tataataaag
    57481 agcaatcaga acaccagccg cacccgcaag agcagaaccc aaagcgaagg taaagctaat
    57541 cgtacggttt acattgatcc ccatcaattg cgccgcgtcg ctatctactg atactgcacg
    57601 catggctttc cccatcttag tcttttggac aatgacttgt aataaaatca tcaaaatcaa
    57661 ggaaatggcc aaaatcatta actgcacatt tgttaagcta attggtccca aatcatatcg
    57721 aactgtttga atcgcttgag ggaaggcacg ggtattggca ccaaccagat agaccattcc
    57781 atactccaat aggaaagaaa ccccaatagc cgtaatcaaa acagcaatac gagtagagtg
    57841 gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca agaatagctg tcgctagcat
    57901 agctacaata agcgctacaa agaaattcat ttggaaagaa ttgatcaaga aataaccgat
    57961 aaaggctccc atcatataaa tatcaccatg ggcgaagttg atgagcttga taattccgta
    58021 aaccatggta tatcctaggg ctaacagcgc gtaaacacta cctagaatca aaccatttac
    58081 gagttgttgg agcataagat tcactctttc tatttataat tccgagggtt ttccctcact
    58141 ttttgatagg ttcttatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
    58201 ttgctcaaag cactgctttg aggttgtaga taagactgac gaagtcagtc acatatataa
    58261 tccaaggcga cgttgacgca gtttgaagag attttcgaag agtattaaat atcgaaacag
    58321 ggagtgagtc aaaggctcat tccctatttc aacatttttc tattatggtt ttacaacttc
    58381 tgctgcttca actttaccat tgttcatggt catcatgtaa gcagttttga ctgtgttgtg
    58441 gtctgcatcg aagcttgttt gaccagttac accttcaaaa tcttttgttt tagcaaggtt
    58501 atccttgatt tcacctgaat ttttagcacc ttttgctgcg tttgctacaa ggtgaactga
    58561 atcataagcc aaggctgcaa atgttgaagg ctcttcattg tacttagcac ggtaagcgtc
    58621 aaggaaggct ttagctttag ctgaaacttc tacagtagtt gagaagcctg agataaagta
    58681 gatgtttgat gctttttcag cagttgcttg ttgtacaaac tcctcaccgt tgaatccatc
    58741 accaccaacg attggtttgt caattcccat gccacgcgct tggtttacaa tcttaccagc
    58801 ctcattatag taaccaggaa caacgatagc atcaaagtct ttccctttca tttttgtaag
    58861 ggctgcttgg aagtctgtgt cacctgctac gaaagtttca tctgcaacga tttcaccctt
    58921 gtatgactcg cggaaagatt tagcaatccc tttagcatag tcactggcat tgtcagtgta
    58981 aagaacaact ttcttagcat ttaatttttc agaaacatag tttgagataa tttttccttg
    59041 gaagctatct tggaaagttc caataaagag gtaatcttga cctttagtca atccatcttg
    59101 agtcgcactt ggtgagatca atggaacacc tgcttttgta gcgttcgcta ccgcagctgc
    59161 agtcgcacca gatgtcgcag gtcctacgac tgctgatact ttagattggg ttacaaggtt
    59221 agttgtaact gaagcagcct cagctgtttc agacttatta tctttatcga ctacttcgat
    59281 ttgttttcca tcgataccac ctgcggcatt gatttcatca acagccaatt gggcaccttt
    59341 ttgttcagct gttccgtatg cagctaaaga acctgattct tcaaagttaa acccgatttt
    59401 aattgtcttt tcctctactg agttaccagc agtgttgact gctccagact tcacttctcc
    59461 acaggctgca agaagtgcta cacttgcaag cgccacaaac gatagggcaa attttttctt
    59521 catctttttg tctccttatt tcttaaatag tctgttaaga atataccgaa ttatcagaaa
    59581 attgtcaatg ttttccttga actttttcga tgataacgtt ttcctatcga taaagattgc
    59641 ccacaaaggg tgtttccaac tcttggatat gacaaaccct aactttttta ataaattttt
    59701 ccttgctcaa gcgtccgacc aattgctcca cttcttgagt tggaacatag agttgtaagt
    59761 aacgatgttt cttggaatga taggtaatat ctccataatc ctgcagtttt ttggcatcac
    59821 gattatagta aagatagata atcaagccag agcgattgac tttttcaaac atgataaatc
    59881 ctctttctaa gaaatctctc cctattatac caaaaaaagc aaacccagtc gagtttgcct
    59941 tctatcatca ttagttcaat gaattgttgg ccataatttc atcaataaag ccatattcaa
    60001 gtgtttcctg ggcgctcatc cagttatcac gttctgcatc tgcatggact ttttccattg
    60061 actgacctga attttcagcc aagatttttt ccaaggtatt acgagttttg agcaagtgtt
    60121 ctgcagcgat agccatatca gtttgttggg taccaccacc tgtaccgccc attggttggt
    60181 gaatcatgta ttcagcattt ggaagcatga aacgtttgcc ttttgctcca cttgatgcga
    60241 tgactgttcc catagatgca gccattccca taacaatggt ttggacatct gccttgataa
    60301 agttcatggt atctacgatt gccaaaccag ctgaaacaga accacctggt gtattgacat
    60361 aaaggtaaat atcttttgta ctatcttggg catccaagaa aagcagttgg gcaataacag
    60421 agttagccat attgtcttca accggacctg tcagcataat gatgcggtct ttgagaagac
    60481 gtgagtaaat atcgtaagaa cgttctccac ggcttgtttg ttcaataact acaggaatca
    60541 ttcatttctc cttttgagtt ttaattttgt tggtcaaatg actgaagata agactattat
    60601 aatatcttgg tcaaaaaagg tcaaattttt gctctgcttt cattagacag aaacaaaaac
    60661 ccaacctcct ttcgtgactg gaaatacttt tccaagtcat tcttcttttc gatcttattt
    60721 tgtaccgaac aagcggtctc cagcatctcc aagacctgga acgatataac cgtgttcgtt
    60781 caaacgttca tccaaggctg ctgtaaagat ttctacatct ggatgagctt cttgaagggc
    60841 ttttacaccc tctggagcag atacaaggca gacaaatttg atatttgatg cgccacgttt
    60901 tttaagagaa tcaacagcca agattgctga gccacctgtt gccaacattg ggtctactac
    60961 aaaaatttga cgttggtcaa tgtcctcagg caatttcacc aagtattcaa ctggttgaag
    61021 tgtttcttca tcacggtaca taccgatgtg gccaacttta gcagctggaa ccaagctcaa
    61081 gagaccatca accatcccga tacctgcacg caagattggg acgatggcca atttcttacc
    61141 tgccaattgt ttttgaactg tttttgtaat tggtgtttcg atttccacat cttctagtgg
    61201 aagatcacga agtacttcat accccatcaa cattgcaatc tcatctacta gctcacgaaa
    61261 agcttttgta gaagtatctg tacgacgcaa gattgacaat ttgtgttgaa tcagtgggtg
    61321 attaataact tcaatttttc ccatttttgg aattccttct ttcaatttat tcttcttatt
    61381 ataccaaaaa acgggttaaa aatctttcta aaccatttat ttttgataat ttttacatta
    61441 gatcagcctc tttaagagct gtctgtactg tctcaagtgg taaatgggtc aattctgtcc
    61501 ctttttcttg ataaaggtat tgggcgtagt cgtccattcg gtactggttg atataaacca
    61561 cacgcttgca gccgacctga agcaattgtt ttgtacagtt gagacaagga aaatgggtta
    61621 cataggctgt aaaacctttg ggaacaccac gctcagcacc ttgaaggata gcattgacct
    61681 cagcgtgaag ggtgcgaaca cagtggcctt caatgaccaa acattcgtga tcaatacaat
    61741 gctcagtccc tgacaccgaa ccattgtaac cagtggaaat aaccttatta tcttttacca
    61801 gaatcgcgcc cactttagca cgtttacaag tggaacgatt cgcaattagt agagcttggg
    61861 ctgcaaaata ctcatcccag gccagtcttt tttcagtcat ctcttttctc ctttttctct
    61921 attttttaaa aaatggtaaa cctaaatctg caatcttttc agctggtacc ttcatgccat
    61981 ccttgatcca ttttagaagg acagagacga tggctgagct ccagaaggaa tgaagataag
    62041 agctgacacc ttttgatttc ccatggtatt tttctagaaa ttcctgcatg gcttggacaa
    62101 agattttttc cagatggtaa tccaaggcca attgaattac tctagcttcc tttctggcct
    62161 cccggaaaag gtgaacccaa accaaataaa ggtctgtctt taaatcgtaa tgatgcagct
    62221 gttccataat attgtggaca gttcgtttaa agacgctctc taaaatttcc tctttggagt
    62281 cataattgcg ataaaaggcc gcacgcgaaa cacctgcacg tttgaccaat tcagaaatac
    62341 taatcttggt cagttccttt ttttccaaga gttgcaagag ggctgtttca atggcttctc
    62401 tggttaataa attggattct tggtttgatt ttctgagatt ttcaagagac ttttcagaga
    62461 ttctacgttc agacataaca ttttctttct acttgtcaca acagacggat gatgcttttg
    62521 tttcaagggt tttcatgata taattgtaaa aaaagacaga acctttgtca atgtataact
    62581 gacaaagatg gagaatttct atgacttgga agattattgc tgactctggt tgtgattatc
    62641 gtcaactgcc aacaccagct attaacacaa cctttgtaag tgtcccctta accattcaag
    62701 tagctgatca ggtctttgtt gatgacgcca gtctcgatat tgaccaaatg atggaaacca
    62761 tgtatgcaac tgcagaagct tcaaaatcgg cttgtccaag cccagatgac tatttgcgag
    62821 catttgaagg tgccaaaaac attttcctag taaccatcac aggtaccctt tctggcagtc
    62881 acaatagtgc tcaactagca aagaatattt atctggaaga ccatcctgac actaagattc
    62941 atgtgattga tagtttatct gctggtggtg aagttgacct actcgtagaa aaattgaatg
    63001 acttgattga ccagggcttg tcttttgaag aagtggttga agctatcacc gcctatcaag
    63061 aaaaaactaa gttgctcttt gtcctagcca aagtcgataa cttggtgaag aacggccgtt
    63121 tgagcaagct tatcggtacg gtcgttggcc ttctcaacat tcgtatggtc ggaaaagcta
    63181 gtgaaactgg aactctcgaa ttgctacaaa aagcaagggg atcaaagaaa tcagttcaag
    63241 ctgcctatga tgagttagta aaagctggat atgctggtgg ccgtattgtc atggcccaac
    63301 gcaataacga aaaatgttgt caacagctct cagagcgaat ccgtgaaacc ttcccacaag
    63361 cggatattaa aattctacca acctctggtc tctgcagttt ctatgcagaa gatggcggtt
    63421 tgctgatggg ctatgaaatt gattaattgt attcttgaca agaggtgacc atcatctctt
    63481 gtttttttgt ggtacaatag agctatgaaa cattttgata ctattgtcat cggtggggga
    63541 cctgctggta tgatggctac gatttccagt agcttttatg gacagaaaac cctcctcatc
    63601 gaaaaaaatc ggaaacttgg aaaaaaatta gctgggactg gtgggggacg ttgcaatgtg
    63661 accaacaatg gtagcttaga caacctgcta gctggaattc ctggaaacgg acgctttctt
    63721 tacagtgttt tctcccagtt cgataatcat gacatcatca acttttttac agaaaatggt
    63781 gttaaactta aggtcgaaga ccacggacgc gtctttccag ccagtgacaa gtctcggact
    63841 attatcgaag ctttggaaaa gaaaatcact gaactaggtg gtcaagttgc tactcaaata
    63901 gaaatcgttt ctgttaaaaa agtagatgac cagtttgtcc ttaagtcagc ggatcaaacc
    63961 ttcacttgtg agaaactcat tgtcacaaca ggtggtaagt cttatccttc gactggttcg
    64021 actggttttg gtcacgagat tgctcgccat tttaagcata ccatcaccga tcttgaggct
    64081 gctgaaagtc ctttattaac agattttcca cataaagcct tacaagggat ttctctggac
    64141 gatgtgaccc taagttatgg taagcatgtc atcactcatg atttactctt tacccacttt
    64201 ggtttgtcag gtcctgctgc cctacgcatg tctagctttg tcaaaggtgg ggaggttctc
    64261 tcactcgatg ttttgcctca actttctgag aaggacttgg ttacatttct agaagaaaat
    64321 cgggaaaaat ccttgaaaaa cgctttaaaa accttgttac cagaacgctt ggccgaattt
    64381 tttgtacaag gatatcctga aaaagtcaaa cagctgactg aaaaggaacg agaacaactt
    64441 gtccagtcca ttaaagaact taaaattcct gtaactggaa aaatgtccct tgcaaagtcc
    64501 tttgttacca agggtggagt cagtctcaag gaaatcaatc ctaaaaccct tgaaagtaag
    64561 ctggtacctg gcctccactt tgcaggcgaa gttatggata tcaatgccca cacgggtggc
    64621 tttaacatca cttctgccct ctgtaccggc tgggtggcgg gagcaaatcc aatctaaata
    64681 tacattacta aatggaacaa tccccccaaa aaaagaaagg aactactttg gaacatatta
    64741 tcttgctaag gggagtcact cctaatggaa aaaatgctat ccctaaaatg tcttatctag
    64801 tagatatctt gacagaagct gattttcaac aagttcgaac ttatattcaa agtggaaata
    64861 ttattcttga aagtaactta gctctcgaag aaatacgaga acaggttcat actctattag
    64921 acttcctgca aaactagaat cctagttcat gattgataat accagcaatc aaattcattc
    64981 gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta
    65041 ctttggcaaa gatgttctca accttgcttc tctccttaga tagcgcatgg ttataggctt
    65101 tatcttcagc tgttagtggc ttgagtttgc tggatttacg tggaatttgt gcttgaggac
    65161 atatcttcat gagcccttga taaccactgt cagccaagat tttaccagct tgtccgatat
    65221 ttctgcgact cattttgaac aacttcatat catgacaata gttcacagtg atatccaaag
    65281 aaacaattct cccttgactt gtgacaatcg cttgagcctt catagcgtgg catttctttt
    65341 taccagaatc attcgctaat tcttttttta gggcgattga tttgtacttc cgtcgcatca
    65401 atcattaccg tgtcctcaga gctgagagga gttcttgaaa tcgtaacacc actttgaaca
    65461 agagttactt caacccattg gctccgacgg agtaagttgc tttcgtgaat accaaaatca
    65521 gccgcaattt cttcataagt gcggtattct cacacatatt gaagagtgcc cataagaagg
    65581 tcttctaggc ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg ataagctgtt
    65641 tttaatacag ctaacatctc ttcaaaagtg gtacgctgaa caccaacaag acgcttaaat
    65701 cgtgcatcag ttagttgttt acttgcttca tcattcatag aactactatg ccatattttg
    65761 tttcgcagga agtctgatca tttcaaatcc agccattgct ctaggagctc aagcgacctt
    65821 tatcctattg aatatcttca ttgtatcacg tggggttcaa aaagggattg aaagagcttc
    65881 gaaagtcatg atgcccctgc tctttatcat ctttgtcgtc atcatcgaac gctctctcag
    65941 tttgccaaat gccatggaag gggttcttta cttcctcaaa ccagattttt caaaactgac
    66001 tagcgctggt ctcctctatg ctctgagaca atctttcttt gccctctcac taggggttac
    66061 agccatgttg acctatgctt cttacttgga caagaaaacc aatctggtcc agtcaagaat
    66121 ctccatcgta gccatgaata tctcggtatc catcatggca ggtctagcca ttttccaagc
    66181 tcggtccccc ttcaatatcc agtctgaagg gggaccgagc ttggtcttta tcgtcttgcc
    66241 tcaactcttt gacaagatgc cttttggaac cattttctat gtcctcttcc tctttgcgac
    66301 tgtcacttct tctgtcgtta tgctggaaat caatgtagac aatatcacca atcaggacaa
    66361 cagcaagcgt gctaaatgga gtgttatttt aggaattttg acctttgtct ttggcattcc
    66421 ttcagcccta tcttacggtg tcatggcgga tgttcacatt tttggtaaag ccttctttga
    66481 cgctatggac ttcttggttt ccaatctcct catgccattt ggagctctct tcctttcact
    66541 ttttacaggc tatatcttta aaaaggctct tgcaatggag gaactccatc tcgatgaaag
    66601 agcatggaaa caaggactgt tccaagtctg gctcttcctt cttcgtttcg tcattccaat
    66661 catcatcgtg gtcttcatcg cccaatttat gtaatcaaaa ggacttgagt aatgaactca
    66721 ggtcctttct tttttatgga tgactaacaa ttaattctaa atcttgccct tctagagtcc
    66781 aagattcaac atcacttggt aggataaagt gtctcccttt ttggattgga tagtttttcc
    66841 cgtcaacagt tagttgacct tgaccagcca agacactcaa caagctgtag tcagctgtct
    66901 tttcaaagtt aacttttcca gtaatttccc atttgtaaac tgcgaagaaa tcattggata
    66961 caaggagagt ggaacgtaga tcatctgctt tgattgtcac tggacggcta tttgcaggtt
    67021 caccaatgtt caagacatcg atagattttt caaggtgaag ttcacgtaaa ttgcccttgt
    67081 catccttacg gtcaaagtca tagacacggt aagtggtatc gctagactgc tgggtttcaa
    67141 gaatcaagat acccgccccg atagcgtgca tggtaccgct tggtacatag aagaaatctc
    67201 ctgctttaac tggcactttt gtcaacagcg catcccagtt cttatcctcg atttgctgac
    67261 ggagttcttc ttttgacttg gcattgtgac cgtagataat ctctgaacct tcatctgctg
    67321 caatgatgta ccaacattct gtttttccaa gttcgccttc atgctcgagt ccataagcat
    67381 cgtctgggtg aacttggaca ctgagccagt cgttggcatc gaggatcttg gtcaaaagtg
    67441 gaaatacagg ttctggacga ttgccaaata attcacggtg ttccgcatac aaagtagcaa
    67501 gatctgttcc ctcgtaacga ccattggcaa ctttagaaac accatttaga tgagctgaga
    67561 tagcccagta ctctccgact ttttcacttg ggatgtcgta gccaaactca tcacgtagct
    67621 tggtaccacc ccagattttt tcttgcataa ctgattgtaa aaataatggt tctgacatct
    67681 taatctcctg tctgattttt ctcccctcat tatagcaaaa aaagagttcc atttgaactc
    67741 ttttttacat cttataaagc agggagaaga ttttataaaa atagtaaaca aatgtgctct
    67801 actcgatgct tacaccattg ctataaatga catgtaccaa tagaaggact tcttcttgct
    67861 acgtttgaga gtcccatttc ctacattatc tcgatctaca tagataaagc catagcgctt
    67921 attcatttcc cctgtgccag ctgaaaccga atcgatacag ccccatgtcg tataaccaag
    67981 caagtcaacc ccgtctttgt aaatggcatc tcgcatggcc ttgatgtggg cctctaagta
    68041 agtaatccga tagtcatctg ctacataacc tttctcatcc ggtgtatcca tagcaccgag
    68101 tccattttct acgataatac tatactaaaa tcaaaaagca ttatataata gtgatatgaa
    68161 atcaactaaa gaagaaatcc aaaccatcaa aacacttttt aaagactctc gtacagctaa
    68221 atatcataaa tgccttcaaa tcattctatt tcgtctgatg ggcaaatctt ataaagattc
    68281 cgactaatat tggctttgca tttattcctc catacacacc agagatgaac cccattgaac
    68341 aagtgtggaa agagattcgt aaacgtggat ttaagaataa agcctttcga actttggaag
    68401 atgtcatgaa tcaactccaa gatgtcatac aaggactgga gaaggaggtg ataaagtcca
    68461 tcgttaatcg gagatggact agaatgcttt ttgaaaacag atgagtatta tatgcaattt
    68521 ctttatataa aaagaccgga ttgctccgat ctttcaatag ttcatattct caatttctat
    68581 tttaaaaata gctaaggtta acgtcaaatg actacgcgac ctatttcata cgataaaaat
    68641 caagcactag accagcaggt ccttgaacta ataaggactc tgttccccaa tcggttacag
    68701 ttggtccgtg taaaaccttt ataccaagct cgttcaaccg tttgtagttc tggtctacat
    68761 cctcaacctc gatatgaata atgattcctg actgaaagtt ttccaaagga accaaatgat
    68821 tttgtgacaa cataaggcag tgactaccaa tcgtaaactg agcaaaacca tcatcagcat
    68881 aatctgcctt tttatccaag atatgctcca agtcagcaca gacttgggga acatttgaaa
    68941 cgataatatc taattgattt aaattcattt actctcctcc ataaaaagac cggattgctc
    69001 cgatctttta aagttctgct ctatgaaaat caaagaataa agtctacaag tttcatattt
    69061 gattttcggc gagaggaatt atttaattgc gcgtgattgc aatccttctt cttccaagaa
    69121 gagacggaat ggtacgagtt cttctgcttc gtatttttcc ttgaaggctt tgatagcttc
    69181 ttctgagtga agttttggat ccaattcaag tacttctact ggaagtggac ggtgttgagt
    69241 gatgcgagca tcgatgacaa cagttttacc ttctttgttc aatttaacag cttctgcaac
    69301 aactgcatcg atgtcttcga tacggtcaac tgtgaatcca acagctcctt gagcttccgc
    69361 aattttagcg tagtcagcgt ttgtgaagtc tacaccaaac aagtgtttgt ttgtatcttc
    69421 gtatttgttc ttgatgaagc cgtactcagc atttgagaag acaaggttga taactggaag
    69481 gtcgtattga acgtttgtga taacgtctgg gtagcacatg ttgaatgctc cgtcacccat
    69541 gatgttccat acttggcgat ctggattgtc tttcttagca gcgataccac caggaagggc
    69601 aatacccatt gtcgcaaaga gtggagatgt acgccacatg ttcttaggtg tcatgtgaag
    69661 gtgacgagta gatgtttgag tagtgttacc tacgtcgatt gagtagatag cgtcttgatc
    69721 agcatgtttg ttgattgcat tgtaaacttg atacaattgc aattcaccct cagttttacc
    69781 ttcgagtttg ttcatgtaat cacgccagtt ttggttgttc ttaacgtttg cacgccacca
    69841 tggagttgat tcaactgggt ttactttgtc aaggatagct ttagctgctt gaccagcatc
    69901 accaaggatt gaagcgtcaa gggcatgacg tttaccaagt ttgtaagggt cgatatcgac
    69961 ttggatgaat ttttcagtgt tcttgaatgc ttcgtaaact tcagcaaatg ggaagtttga
    70021 accaaggaaa agaactgtgt ctgcttcaaa gaccacttcg ttggctggtt tccaaccaac
    70081 acggtaagca gaacctgtca aaccttcata gttccattcg aaagcttcaa agtttttacc
    70141 agttgtgatg attggtgctt tgattttacg tgacaattca gtaatcactt caccagcttt
    70201 aacaccacca aatccagcat agataactgg gcgttcagca ttgttcaaga tttcaacagc
    70261 tttgtcgatt tcaacttcgt tcaaagcagg agcgatgaat gagcgttcgt atgaacctga
    70321 accgtagtat gagttttcgt cgatttcttg gaaaccgaag tttactggaa tttcaacaac
    70381 agctggacct tttttagaaa ttgcagcacg gcaggcttcg tcaattactt ttggcaattg
    70441 ctcagcgtaa gctacacgtt tgttgtaaac agcgataccg ttgtacattg ggttttggtt
    70501 aagctcttgg aaagcatcca tgttcaattc gttaactgga cgtgatccaa ggatcgctag
    70561 gaatggagtg ttatccatag ctgcatcgta aacaccgtta atcaagtgag tcgcacctgg
    70621 accacctgaa ccaactgcaa ccccgattga gccgccgaat ttagcttgca taaccgctgc
    70681 aagagcacct gtctcttcgt ggcgaacttg taagaagcgg atatctttgt cttcagccaa
    70741 agcgtccatc aatgagctga gtgttcctga tgggataccg tagattgtat ctacgcccca
    70801 tgttttcaat acgttaagca ttgctgcaga tgcagtaatt ttcccttgag tcataatgat
    70861 aactctcctt caattttttt agatttggag aatacgatta catagaattg gaaacgttct
    70921 ccaaattttt actattccac tgtatcatat ttatgctgac ttttctaaaa atctgctcaa
    70981 aactctctat tctctattct aatacagttt tgaaagttct gtcatttctg ttttataaca
    71041 aagaaatcta gtcattactt ttagtctatt ttactaaaat ttaacagaag ggaactggtc
    71101 agaacagata cagaactaaa ggccatggct agacctgcca attctgggtt gagagccagt
    71161 ccaacacctg aaaagactcc tgctgcaatc ggaattccga caacattgta gataaaagcc
    71221 cagaaaagat tgagtagaat tcgatgaaag gttttcttac tcatatcaaa ggcacgaacc
    71281 actcctaaaa gattattggt tgtcaacacc aaatctgctg actcgatggc gatatctgtt
    71341 ccagctccca tagcaatccc cacatctgct acactaaggg caggagcgtc attgataccg
    71401 tccccaacaa aggctacttt ccctgactgt tgcagtttat ggatttcatg ggctttttct
    71461 tctggcaaga cgcctgcaat gacctcttca attccgattt gatctgcaat agcacgcgcc
    71521 acatcagcat tgtctcctgt cagcatgact gttcggagac cacgtttttt tagctgactg
    71581 atggctagct tagcattttc cttaggaata tcttgcaaag caagcaagcc tttgatttca
    71641 ttgtcaacag ctaagaacac aactgtctta gcttcttttt ctagttcttc tagtttatct
    71701 tgataagtat tagaaatatc catgccatcc agcattttag catttccaag taaaacttgt
    71761 tttccattga ttcgccctga aacacctttc ccgtgcaagg cctgaaaatt ttcaacagtt
    71821 tgaaactcaa gtccagcttc actcgctcgc ttaacgatag cctcagccag tgggtgttga
    71881 gaagcatctt ccaaggaggc tgccaatcca aacacttcta cttcgtcgcc gatgatatct
    71941 gttaccacag gtttcccttc cgtcaaagtc ccggtcttat caaagacaag agtttgaact
    72001 ttctggattt cctgtaagac agttccattt ttgaggagaa cccccatctt ggcactacgt
    72061 cctgtcccca ccataagggc tgtcggtgtt gcaagtccca aggcacaagg acaggcgata
    72121 atcaaaaccg ccactccgta gagaagagag gacacaaagc tagctccaag cacgaccaca
    72181 ctatccctga gcaagacgaa ccaaacccaa aaggtcatga ttcctaaaat gacaactact
    72241 gggacaaaaa tccctgaaat cttatccgtc aagtcctgaa tcggcgcacg acttgtctga
    72301 gctttcttca caaaatccac aatctgagcc aaaacagtct ctgagccaac tttttctgct
    72361 ctaaagacaa gcgttccact atgattgatg gttgagccaa tgacagtatc tccaactgtc
    72421 ttgtccacag gcagactctc acctgtcacc atggattcgt caatactaga gacaccttct
    72481 actacgacac catcaacagc aatcttttca ccgggacgca ctcgaatcag gtcgcctacc
    72541 ttgacttgtt ccaaaggaac ttggacataa ctatcatcac tcaagacttc tgcggtttta
    72601 gcttgcaagt ccagtaattt ctccacagct tgggacgtat tttttctcat tttttcctca
    72661 aaaactgctc ccaaaagaac gaaaaagagg ataaatccag cactttcgaa gtaaacaggg
    72721 agaccagcaa agagagcaac taggctatag aaataagcca ctagagttcc cagcgcaacc
    72781 aaggtatcca tgttggcatt gtgcttttta aaactggccc aagcactctg gatatatggc
    72841 ttacctgcaa ctaacataat aggcgttgtt gctagaaagg ttccccaatg catgacttga
    72901 tgactaatgc tacctgtcaa catcccaatc atgagaatca caagaggcac agtaaagata
    72961 ctagtaatcc aaaaacgttg caggagagat agagattttc gagtcttctc aacgactata
    73021 tagcttccct tttgcatctt catgccacaa gaaaattcat gtcgccctaa ttcttgaggt
    73081 gtaaaacgaa tgactttctc ctcatctacg ccgattggtt ccaagatacc ttcttcttca
    73141 aacagaattt ccttataaca gtttgaagga gtagcacgat gaaaggtaat ctcagctgga
    73201 attccctttt gaagctggat atgggctgga tgatagcctt tttcagctcg gatacggatt
    73261 ttttgaatgc cattttctaa gcttgctttc acaatttctg tcatagtctc cacctactct
    73321 acaatcatct tgccgtgcat catgttcata ccacaagcaa agccaaactc tccagcctgt
    73381 tcaggcgtga tttccactac atactcttcc cccattggca ggttcgcatg tacaccaaaa
    73441 tctggaaaaa caatttgatc cagacatggt gaaggatcct tgcggtcaaa gacaatgcgg
    73501 gctggcactg atttcttgag gacaatcaac tcaggagtat agcctcccat gacttccact
    73561 cgaatctctt ggtatccgtt tttttgctgg gctttttgtc cagatttttc aggctttttg
    73621 aaaaaccaaa acaagataaa cgcgataagg gcaatacaaa taatggttac aatactattt
    73681 aacatgacgt ctcctttaca tacaattaca tcttacttct gttacagcac ttgatttctt
    73741 ctctgaaatc acagcttcca agtcttccaa gtcagtctga gtaaattcac attctacaat
    73801 caagtcagcc aacaaattcc taatcctacg ggaacaaacc ttgtctttga tatcttggac
    73861 aagtaaatcc cgactttggt ctagagttaa aagggctgaa taaacaaaga acttgccttc
    73921 ttttttccga gtcagacact ctttctcaac caaacgagcc aaaagagttt gaatggttga
    73981 cttggaccag tcgaaccgct ctgccaaaac cctaatcaaa tctgtactgg tctgctcccc
    74041 ctgcatccaa ataatcttca tgacctgcca ttctgcatct gaaatctgca ttaccatacc
    74101 tccaaaatct acatttgtca attacactca tcagtatact cttaaaatct acatttgtca
    74161 attatagaaa taatattttc ttcgaaaaat agaattttaa tcatttgaaa aacgatttgc
    74221 agtcaaatat tactatataa acaataaaaa tatgctatac taaagaaaaa agaaaacaac
    74281 cactaggggt gcgtaaagct gagattaacg actgttagat ccctctgact caatctaggt
    74341 aatgctagct gatggaagtg gaaatgataa tggggactag cagtcttcta ttgcctttct
    74401 aaaacagact agcttgttct taagaataca aacttcagtt ggttgggagg ttttagatga
    74461 cttatttacc cgttgctttg accattgcag ggactgaccc tagtggtggt gctggcatta
    74521 tggcagattt aaagtcattc caagcgagag atgtctatgg aatggctgtt gtaaccagtc
    74581 ttgtcgctca aaataccaga ggtgttcagc taatcgagca cgtttctcct caaatgttga
    74641 aagcccaatt ggagagtgtc ttttctgata ttccacctca ggctgtaaaa actggaatgt
    74701 tggctactac tgaaatcatg gaaatcatcc aaccctatct taaaaaactg gattgtccct
    74761 atgtccttga tcctgttatg gttgctacaa gtggagatgc cttgattgac tcaaatgcta
    74821 gagactatct caaaacaaac ttactacctc tagcaactat tattacgcca aatcttcctg
    74881 aagcagaaga gattgttggt ttttcaatcc atgaccccga agacatgcag cgtgctggtc
    74941 gcctgatttt aaaagaattt ggtcctcagt ctgtggttat caaaggcgga catctcaaag
    75001 gcggacatct caaaggtggt gctaaagatt tcctctttac caagaatgaa caatttgtct
    75061 gggaaagccc acgaattcaa acctgtcaca cccatggtac tggatgtacc tttgctgcag
    75121 tgattactgc tgaactagcc aagggcaaga gtctttacca ggcagttgat aaggccaagg
    75181 cctttatcac aaaagctatt caagatgccc ctcaactcgg tcatggttct ggtccagtca
    75241 accatacaac ttttaaagat taagaaaaaa actctctagt tcccacttta agggaattag
    75301 agagttttta tactcttcga aaatctcttc aaactacgtc agcttccatc tgcaacttca
    75361 aaacactgtt ttgagctgac ttcgtcagtc ttatctaaaa cctcaaggca gtactttgag
    75421 caacctgcga ctagctttct agtttactct ttgattttca ttgagtatta attaggaaag
    75481 aatgtcatgc aactttgtta aaaaggcttg cgtttttgcc tcaatatctt ctgcttgcat
    75541 caaatcacgt acaacagcta caccagctat gccagtgccc ataagctgat caatattctc
    75601 cgaagtcaag ccgccaatag caactattgg aatggcaacc gtttggcaaa ttgttttcaa
    75661 ggttgaaatc agggtgatgg gtgcattttc cttggtggtt gtcggaaaaa tggctcctgt
    75721 ccccaagtaa tctgcacctg atttctccgc ttccagagct cttttaaccg ttttagcggt
    75781 gacaccgagg attttttcag gacccaagac ttgtcgggca accgaaactg ggagttcgtc
    75841 atctccaata tgcagaccag cagcatcaac cgcaagacaa acatccaacc gatcatcgat
    75901 tatcaagggt acctgataag catctgttat ttccttgact tgttttgcca gttgataata
    75961 ttgattggtt gtgagatttt tttctcgcaa ttggactatg gtaacccctg aacggcaggc
    76021 cgtctcaact tttgcaagaa agctttccac ggaatcttga tagcgattgg ttaccagata
    76081 tagtctaagc gcttctctat tcataaacct ctcctttgat ggtatctagc caattttcat
    76141 ctcttcttag gagcgaaagc tgattgagta cttggtaacg aaattcttcc aatcccattc
    76201 cttgaacaac tattttctca gcagcgatat tgagataaga gactgctaag caagaagctt
    76261 caaaaccagt ctttccttgg ctgagaaaaa cagctgttaa ggctccaacc aagtctcctg
    76321 tccctgttat ccagtctaat tcagtacagc cattctcaag tacagcaact tgattctccg
    76381 aaacaataag gtccttggga cctgtgacta agaatggcat accaggatag gtctgacacc
    76441 agtctttcaa gacttgaagc aaatcctccg tttcttgatc tttagcactc gcatcgaccc
    76501 caacgccgtg atgctttaat ccaacaagac ttcgaatttc tgacatgttt cctttaagga
    76561 ccgtaggtct atagtctaaa aggtctttaa ctaagctctt acgaatggat gaagtcgtta
    76621 cgccaaccgc atctactacc atcgggagag aagattggtt tgcatacaaa gctgccatgc
    76681 ggattgcttt ttccttctca gctgacaaat gccccaaatt gatgaagaga gcctggcttt
    76741 gcttagtaaa atcaagaact tcacggggat catctgccat gacaggtttg catcccagag
    76801 ccaaaatccc atttgccagc atctcacaag aaatctcatt ggtcatacag tgaatgaggg
    76861 aactagagcc tataggaaaa ggatttgtca atgcctgcat cattctatcc tttcagcaaa
    76921 gaaatatcct tgcacttttt taaagaattc ctgcttgatt aaaaatctaa atgcaataaa
    76981 ggaaatcgct gtaccaatca aggttgctcc gaaaaatcga ggcgtgtaga taaaccaact
    77041 aagcttagca gccgatcctg taaagagcac cataacagga taggaaacaa tagaaccaat
    77101 aatacctgtt cccacaattt ctcccaaggc agaaaagtaa aattttcgac cgtacttata
    77161 aaagagacct gctagaaggg ctccaaaagt cgctcctgtg agagctaaag gcggaatccc
    77221 ttgagtcgtc atacggataa aggctgtcac tgtagccata gccaaggcat aaacaggtcc
    77281 catcatgatt cccgctagaa tattgactac actggacatc ggtgccattc cctcaatccg
    77341 aaagataggt gtaaggacta catcaagggc aatcatcata gataaaatgg tcaatttgtg
    77401 aacttgtagt tggtgctttc tcatgtttct attcttctcc tttttctaaa gactgtaaat
    77461 cgctcttcca tgtctggtgt tggtaagcca tctcccaaaa cttggcttcc acatgaacac
    77521 tgatgtggaa ggcatctagc attttttgct tatctgtctc atcactttct cgatagagct
    77581 gattgaccag tgctccctcc tctctgatct gttgctctaa ctcatccgta atataagttt
    77641 caatccattg ttgatagaga ggatttggtg atggtttaag attaagtgat ttgcctatat
    77701 catggtataa ccaaggacaa ggaagcaagc ttgcaaaagc gatggctaag ttcggttctg
    77761 caaattgcct ataaatatga gaaatgtaat gataacaggt tggagcaatt ggatgttgct
    77821 ccatttcctg gtcgctgatt tccatttcct tgaaaaattg ttggcgaata aataactcac
    77881 cctccactaa accctgagca ttttgtttca agagtctttt catctcttgg tttgaagtct
    77941 tatcagccaa aagatgatag atttctgaga aggccttcag atagtaggca tcctgaatca
    78001 ggtaatagcg gaaaatggca gattctaaat tcccctcttg taattgtaaa ataaagggat
    78061 gatgaaagga agcctgccaa gctttcttgg ataattccat cgcaatatct gtaaattcca
    78121 taataactcc tttataaaaa tagactggtt tgaagcaata aaaagaaaag caggtagatt
    78181 aattttgttt ttttaggaat ataaaaagtc cgatagctat tcttcaactg tgcatgttcg
    78241 tcatatccat gagcagacag agctctcagg taaagatggc gccacctaaa gactgtcatc
    78301 agaaccttac tgtaaatcaa gggcgaccaa aaatgcagtt cttgaccacg taataggcaa
    78361 gcttctttga gggacttgat ttcttgctga atgagaggaa aggaattgaa taccacaatc
    78421 aaggcatagg accaagagcg tgatagcccc ttttgagcca agtacaagag aagctctttt
    78481 agtgaaatag aggaaacaaa gacaaggccg atacaaactg tcacaaaggc cctcgttcca
    78541 agcatgactg cctgtgaagc atctccgtgt aactgaactg cccagtagtt ggcaaaagat
    78601 ggtaaaatgg caagtatgat catccaagct aacattttaa atcgacggta atagagcata
    78661 aagagaatac aaaatgcgac taccgaaaga ttcagagcaa tcgaaggaat gaaagatgtt
    78721 tccaaggata aaatcagcaa gaagagactg ataatcggtg tctgggttgc tactttgacc
    78781 atactatctc acctcccctt gggtattgct actctgagat gtaagtggtt tggtaatggt
    78841 cacttctttc acatgactga gcccctgact agtcatctca atccaataat caaccacaga
    78901 aatcaaaggg tctaaacgat gactaatgag cagaaaactt cttccttgat tcctctcctc
    78961 cacaatccac ttgcaaaaat aatggcaggc tctatcatcc aaacctgcaa aaggttcatc
    79021 tagcaagatc acggaagcct tactggtcaa gatggtcagg agctgaagaa ttttttgctg
    79081 accaccactt aattgatagg gactcttatc gactgcctgc tccaaatcaa aatatcgtaa
    79141 agcttgaaaa atccgctgat ttctttcaga atcaggtcca tctaatcgaa gctcctctcg
    79201 cagactgact cggataaact gcttctcagc ttcctgaaca acacccgtca gatcacggta
    79261 caaactcttt ttctttttca ggactgtccc cttccatgca atgcgcccct tatacttttg
    79321 aaattgaaga atagagcgaa agagggttga tttcccgaca ccattgtcac ccaggataca
    79381 ggaaatccct tgatagaatg tgaaatcagc aattgaaaag agggggcgat taccaagctc
    79441 accagtcaca cggttcatat ggaatagttc cgggctagaa gcaacttcct ttgaagcaac
    79501 ctgtgtcatc tcataggaag ggatttgaaa cacttccctt agttttccgt ctcttagctc
    79561 aaccatatgg tcgatatagg ctttatagtc agataaatca tggtcgcaca aaataactgt
    79621 cttcccatca agagccaact cttttagaat ctccaatatc tcgattctgc tcttgcggtc
    79681 aatagaagcg aagggctcat ccaagagata gaccctagga ttcatggcaa agaggacagc
    79741 cagcgctgct ttttgctttt ccccacctga taggtgatga atgggacggt gtaagattgc
    79801 ctcgcaacga cattgctgga caacctctgc tattttagaa tcaatttcct gaaggtgata
    79861 gccgatattc tccaaggtga aaatcagctc ctcaaacaag ttctccatgg taaattgatg
    79921 attgggattt tgaaagagaa tgccaacctt ctggacacgt gcgatgatag aaagctgact
    79981 gacctcgctc ccatctatca ggacttgacc actataggga agagaactga cttgggcaat
    80041 gacttgaaaa aggctggatt ttcctgaacc actgctccca actaacaagg taaaggcttg
    80101 cgcatgaaaa gtaaaatcaa acggctcaga gaagattggg gactgaatcg ctcgtagttc
    80161 cagacccatc tatgcttttc ctccagttgc aaactgatga tagagtttga caatggcacg
    80221 aaccaagatg gtacagaaga aataaacaga aataaaacgt accacaagta aggaaaggac
    80281 aaacggaagg gaaaaggcgt agtaacctaa cttaatgtat tcatagacaa agctaacaag
    80341 cgtaacccca atactattag cagttagaga gagccaactt tcatagcgat tcttagttac
    80401 gataaaacca aattcacttc ccaaaccttg aaccaagcca aacaaaagag ctcctagacc
    80461 aaattggcta ccataaagga cttcagcaag cgcagctagc acttctccaa tcgttgcact
    80521 tccgactctc ggaacaaaga tggcagcaat gggcgcagcc atacaccaga gaccgaagag
    80581 gatttcattg gcaaaggcct gcaaaccaag aggtgttaag agtagactga gaatattata
    80641 cacatatcct gaaccaacga aaaccccacc aaaaaagata gacaagaaag caagcaagat
    80701 aacatctttt aactgccatt ttttcaacat aaaaaactcc ttttttaaaa gaaaagtggg
    80761 gcactcaaga agaccgacct aaatactttg tatagcagat tgaatttaga acagtacaca
    80821 ggaatgctaa aatatttcta gaaattaatt tgaattttct aattgatttg ttcgcatctt
    80881 atttcaatct actatatcat cttcatccag tttcgtaaaa gaaaaaactc taattacaga
    80941 tacgaattag agttcagctt acaagattag acagttcttt tcgacatacg aaaaaaacat
    81001 ttcacatttc ccttcgccag tcttaactgt atcaggttca atgggtatca tctcagccta
    81061 aagcacccca aatgccttta ttatttaatt atgtgattat tataacacac attttatact
    81121 agttcaagaa attgaactgg agatacagcc ttgcactcac aaagacagca gatctttctt
    81181 ttgcaaaaaa caaatgacct gtttgatgaa ttagccattc aagctgaatc tagacatagc
    81241 tttttaaaaa aggaaaatcc tacttactta gaatccaagg atagatatct attgttcact
    81301 catttcccga acagtttttt ctatattttt tgcatacgat attgccgaaa tgattgaaac
    81361 gccgtcaaca ttggtcttta taatgtcttt aatatgtttc gtctgtatcc caccaattgc
    81421 aactaaaggc atttgtggca atagttttct catcaattca agaccttcat aacctatagc
    81481 accaccagca tcatcttttg actgggtatc aaatacaggc ccaacaccta cataatctac
    81541 atattcaact tttgattgtt gaaattcttc ttcgtttctt atagaaagac caattatttt
    81601 atctggcatc aattttctaa tttcatcaac accaatatca tcttgaccaa catgtacgcc
    81661 atcggcgtca atttccattg ctaaatctat atcgtcatta acgataaatg gaacattgta
    81721 ttttttacaa agttctttaa tttggatagc tagctcaagt ttttctaagc cttctaaagc
    81781 actctcacct ttttctcgaa attgaaataa ggttatacca ccttttaagg cttcctcaac
    81841 gactgtatat agattttttc cttggcaagt agtcgttcca caaataaaat atagttttag
    81901 taattcttta tgaaacatct tacttcactc ttttgaattc ctttacatct tcatctgtaa
    81961 tctcgtataa ggcatttata aattcaactt taaatgtccc aggaagatgt ccatttggac
    82021 gtttttctgc catttctcca gcgatattgt aaactaacat tgctgtttct aatgatttca
    82081 attcttgacc tttttctagt ccgataaagc ttgctactac agctcctaat aagcatcctg
    82141 tcccaatgac tttcggcatc atagcactac cattatgaat cgttaccact tctccattaa
    82201 cagcaatggc atccacttca cctgttacta ctattggaat attgaacttc tcatttgctg
    82261 ctagagcaat ttcgtcaata ttatctacgc ccgcactatc tactccttta gatgccacat
    82321 ctattcctac taaagaggca atctcgccag catttcctct aatcgctgct agtttataat
    82381 tgttgattag atcatctgct actttttttc tatattctcc tgctccacag gctacaggat
    82441 ctaaaactgc tgggacatta tatttctccg caattttcag agcagcttgg tataatttcc
    82501 aattttcatc tgtcaatgtt cctatgttta ttaataaacc accagcatac tttaacaaat
    82561 cctctaaatc tgctggaaac tcactcatgg ctggtgagac gcccagtgct actaatccat
    82621 ttgctgtgaa attttttact acatcattgg ttatacaaat gaccaatggt gctttttctt
    82681 ttaataattt taaacttgtc atattgaaat ccttcctttt cactttatac gatctactga
    82741 tttcgattta tctctatctt tcgttaagaa atttttttca tttacgttga atgatttata
    82801 ctcaatgaaa atcaaagagc aaactaggaa gctaaccgca gattgctcaa aacactgctt
    82861 tgaacctgta gataagactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag
    82921 aactgacgaa gtcagtaacc atacctacgg caaggtgaaa ctgacgtggt ttgaagagat
    82981 tttcgaagag tattacctca tcaaatttgt aaatatcatg agccttctct agacatcgta
    83041 accaatatca aaaaaagcta attctaaagc gactgcttga ttccagcgtt gctgaagttc
    83101 tgtcaaatct tctcgatttt taccgacacg attgagttcg tcaaccagaa attgaaccca
    83161 ctctgcaaag aaaggacctc tgtggagatt gatccattcc gaatgaatat agacttcagg
    83221 taaagccaaa tctttagaac cccagtctaa atagagacct tctgcaatga ccagcatgac
    83281 caaaagatgg gcatagtctg atgaagccac cgccgaatac attagatcct gaaaggcttt
    83341 tgttacaggg tgcaaagtca cttctagata gtcattctct gctactttta actctttaaa
    83401 agccttttgg aaataaccat cttcatctgc ttcaagaaag cctagttgct tggcaaaacg
    83461 aagcttggat tcaagtttat ctgcgtgagc tacgcaggca cccagcatgg ataagaaggc
    83521 atcaaagaag tgataatctt gaatcagata gtcctttaag accttattct caattgtccc
    83581 cgcaaaaagt tccttaacaa aacgatgatt gattgcagcc tgccaatcct tctgactgct
    83641 ttttaataat tctccaacag tcaaacctgg ctgaaatgca tagtcttgtg tttccatatt
    83701 tacttctcct ctctttactt gttagtaatt aataaaacac caagaaatat caagcaaaat
    83761 cgtaattcca cttgatcctt ttaaaacaca tcgagagtat ttgcagagag ctaactaaac
    83821 aagcctatcc agtttatata aacaaaaaac tccaattaca atcaagaatt agagttgact
    83881 tacaagatta gaccgttcat ttcaccatac gaaaaaactg ttcacatttc ccttcgccag
    83941 tcttaactgt atcaggttca atgggtatta tctcagccta aagcacccca aatgtctcta
    84001 ttatttaatt actgaaccag tatagcaaaa aatgaaagcc ttagcaagat atttaaccga
    84061 aaaatatctt tatatatagt agattgaaac tagaatagta cccctctact tctaaaacat
    84121 tgttagaaat cgatttaact gtcctgattg atttgtccta ttcttatttc attttactat
    84181 agttttcgat agcgatttat tcttccaata cacgaagaaa aacctccaca ttcagtgaag
    84241 gcaatctgtt ttatcaatac aattttaagt cacgagggtc aactgggaag gttgggttgt
    84301 atggattgtg acggagctta aagtgtttga catcttcaat ggtctgagct ccagacaatt
    84361 gcataactgt cttcaattcc gcattcaagt gttcaaagac ttgacgcaca ccgacactac
    84421 caccgagagc caagccataa ataacagggc gaccaatagc taccaagtct gctcctgaag
    84481 ccaaggcttt aaagacgtgt tgaccacgac gaacaccaga gtcaaagaca atcggcacac
    84541 gtctatcaac tgcttctgcc acttcttgaa gcgagtcaaa ggcagctggt ccaccgtcga
    84601 tttgacgacc accgtggttg gttacccaga taccagaagc tcctgcagca agtgaacgtt
    84661 caacgtcctc acggcattgt ggtcccttga catacacagg aagaccagag tattcagcga
    84721 taaattctac atcgcgtgga gacaagcgtt gtttagctga tttgtaaaca aagtccattg
    84781 atttaccagc accttctggc aggtattctt caacaatcgg catgccaact gggaagacaa
    84841 aaccattacg cttatccact tcacgattcc cccctacagt agcatctgcc gtcaagacaa
    84901 tcgctttata accttcagcc ttcacacggt ccatgatgtg gcggttgata ccgtcatcct
    84961 tactaaagta aaattggaac caatggggtg tcccttgaag ggcttcagaa atctctggaa
    85021 ggtcaacagt agagtaagag ctggttgtat aaagagaacc aaactcatgc acaccacgcg
    85081 cagtcgccac ttccccctgt tcatttgcca atttatgagc cgcaacaggc gccataatga
    85141 ttggtgaaga tagtttttca cctgcaaatt caatctctgt acttggattt tcaacatcgc
    85201 aaagtgtatg aggaacgatg agtttgtggt taaaggcgcg gatattctct cttaaagtga
    85261 aagtatcttc cgccccacta gcgatatagc caaatgctgc tttaggaata acttgttgcg
    85321 ccattggctc caaatcatag gtattgatga agtctacatg accttctgca ttgcttgttt
    85381 tgtatgacat aaaatgccct ccttgattaa gtaagcgttt gctttttact acacaactat
    85441 aataactctt ttttcaatca ttttcaagag ttttgcttaa aaaccatctt attttttcat
    85501 acaatatact agccctactt tccttaaact ctaaacttta gtctatatta agtgaatcgt
    85561 tgagattttt tgctgccagg catttgaact acttttttat ttgcggattc tatctactaa
    85621 tactataaaa aaacaagtga ataagacacc agaacatcct ctaataggac ctatggactt
    85681 atatcaatcc catatatact gtttaagcaa gatactatcc tagttgacgc taacttccta
    85741 tcccacttat taatttttta tttatagtga atctgaacaa atcaattggg gaatccaagt
    85801 caatttctag tactttttga acagtttcag cgtactatcg taaaatgaaa taaaacatgc
    85861 acaaattgct tagggaattt aaaccaattt ctaacaatgt cttagaaatc aaagtgtact
    85921 atttcaactt caatatacta cacttcattt tctccttaaa ttcagtctct ttttgaatca
    85981 aaaaatcctc tggtaagagc cagaggataa gaatttattt cattgttggg aagagcaata
    86041 catcacggat agttgttgta tcagtgagga gcatgcagag acggtcgata ccgattccca
    86101 aaccacctgt tggtggcata ccgtattcaa gagcttcaat gtagtcatag tcgattcctg
    86161 tcgcttcatc atcaccaagt tctttggctt tagcttgggc ttcaaaacgg ctaagttggt
    86221 cgattgggtc gttgagttca gtaaaggcat taccgtactc cttagtcatg ataaagagct
    86281 cgaaacggtc agtaaagcgt tggtcttcag gatttttctt agcgagtgga gatacagcta
    86341 ctggatgtcc atagacaaag gttggttgga ttaaagtttc ttcaacaaac tcttcaaaga
    86401 aggcattgat gatgtgacca acctcagtgt agtgtttctc aactggaact ttcttctcag
    86461 cagcgatagc tttagcttct tctaaagtca tgtcttgcca gaaatcgaca ccagtaattt
    86521 ctctgatagc atccaccata tgaacacgct taaatggttc gttaatcttg atttcagtac
    86581 cttggtagtt gactgggcca tcgcccttaa ctgatttagc agcgtgttgg ataatgcctt
    86641 ccgtcaagtc catgatgtct tggaagtctg cataagcttg gtaaacttcg atagaagtaa
    86701 actcagggtt atgagtagcg tccattcctt cgttacggaa gatacggcca atttcataga
    86761 cacgttccat accacccacg ataaggcgtt ttaagtgaag ctcagtcgcg atacgaagca
    86821 ccatgtcaat gttttgggca ttgtggtggg tgataaatgg acgggcagca gcaccaccgg
    86881 cttcattatg aagaacaggt gtttccactt caaggaatcc tttttggtca aggtaacgac
    86941 ggatttcaga gatgattttt gaacgagtga caaagcgttc aaagctttca cgattagaaa
    87001 tcaagtcaag gtaacgttta cggtaaattg tttcaacatc tgtcaaacca tggaatttct
    87061 caggaagagg acgaagagcc ttagacaagt gtgtgatgtg ggttgccttg atagagagtt
    87121 ctcccatatc cgtacgcatc acttcacctt cgacaccaag gaagtcacca aggtctgctt
    87181 ttttgaagat ttcgtagttt tcttcaccga cagcatcctt acgaacgtag atctgaatct
    87241 ggccttcgcg gtcttgaagg tgggcaaaac caacttttcc tttaccacgt ttggttacca
    87301 agcgtcctgc gatagtagct gtttcgtttt tatcgtgtaa ttgttcttta tcgaggttgg
    87361 catatttatc ttttaattct tgtgaatttg cagtacgttc aaaacgtttt ccgaaaggat
    87421 cgattccttg ttcgcggagc gcagccattt tttcacggcg aacaatctgc tggtcattta
    87481 gttcttccat atgttctgta gacatgggat cctcctagtt ttactcaaaa ttgaatacga
    87541 tgagtcattt tttgcgatac cccattttat cataaataag caagaaattc acggataatc
    87601 tttaaaaact aaaaagaacc tgacgctaaa atcactggaa agaagtgaaa gtatcttccg
    87661 ccccactagc gatatagcca aatgctgctt taggaataac ttgttgcgcc attggctcca
//
LOCUS       DAVKZI010000003        73393 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKZI010000003 DAVKZI010000000
VERSION     DAVKZI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 73393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.003"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            167..823
                     /locus_tag="VXB18_000221"
     CDS             167..823
                     /locus_tag="VXB18_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0381507.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            813..1022
                     /locus_tag="VXB18_000222"
     CDS             813..1022
                     /locus_tag="VXB18_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0381508.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIK"
     gene            1240..2070
                     /locus_tag="VXB18_000223"
     CDS             1240..2070
                     /locus_tag="VXB18_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0381509.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2224..3078
                     /locus_tag="VXB18_000224"
     CDS             2224..3078
                     /locus_tag="VXB18_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0381510.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3178..4551
                     /locus_tag="VXB18_000225"
     CDS             3178..4551
                     /locus_tag="VXB18_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0381511.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4544..5605
                     /locus_tag="VXB18_000226"
     CDS             4544..5605
                     /locus_tag="VXB18_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0381512.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5607..6299
                     /locus_tag="VXB18_000227"
     CDS             5607..6299
                     /locus_tag="VXB18_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381513.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6329..6898)
                     /locus_tag="VXB18_000228"
     CDS             complement(6329..6898)
                     /locus_tag="VXB18_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0381514.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7033..7647
                     /locus_tag="VXB18_000229"
     CDS             7033..7647
                     /locus_tag="VXB18_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0381515.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7649..9295
                     /locus_tag="VXB18_000230"
     CDS             7649..9295
                     /locus_tag="VXB18_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0381516.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9307..10593
                     /locus_tag="VXB18_000231"
     CDS             9307..10593
                     /locus_tag="VXB18_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0381517.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10645..11178
                     /locus_tag="VXB18_000232"
     CDS             10645..11178
                     /locus_tag="VXB18_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381518.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11256..11726
                     /gene="nrdI"
                     /locus_tag="VXB18_000233"
     CDS             11256..11726
                     /gene="nrdI"
                     /locus_tag="VXB18_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0381519.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12019..13281)
                     /locus_tag="VXB18_000234"
     CDS             complement(12019..13281)
                     /locus_tag="VXB18_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0381520.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13591..14049)
                     /locus_tag="VXB18_000235"
     CDS             complement(13591..14049)
                     /locus_tag="VXB18_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0381521.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14046..14486)
                     /locus_tag="VXB18_000236"
     CDS             complement(14046..14486)
                     /locus_tag="VXB18_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0381522.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14842..16791
                     /gene="mutL"
                     /locus_tag="VXB18_000237"
     CDS             14842..16791
                     /gene="mutL"
                     /locus_tag="VXB18_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0381523.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMALVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17117..17584)
                     /locus_tag="VXB18_000238"
     CDS             complement(17117..17584)
                     /locus_tag="VXB18_000238"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0381524.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17585..18790)
                     /locus_tag="VXB18_000239"
     CDS             complement(17585..18790)
                     /locus_tag="VXB18_000239"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0381525.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDILGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYNSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18810..19445)
                     /gene="ribE"
                     /locus_tag="VXB18_000240"
     CDS             complement(18810..19445)
                     /gene="ribE"
                     /locus_tag="VXB18_000240"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0381526.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19430..20530)
                     /gene="ribD"
                     /locus_tag="VXB18_000241"
     CDS             complement(19430..20530)
                     /gene="ribD"
                     /locus_tag="VXB18_000241"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0381527.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYTFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20664..20778)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20935..21528
                     /gene="ruvA"
                     /locus_tag="VXB18_000242"
     CDS             20935..21528
                     /gene="ruvA"
                     /locus_tag="VXB18_000242"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0381528.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21538..22101
                     /locus_tag="VXB18_000243"
     CDS             21538..22101
                     /locus_tag="VXB18_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0381529.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLYDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22098..22775
                     /locus_tag="VXB18_000244"
     CDS             22098..22775
                     /locus_tag="VXB18_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0381530.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22912..23943)
                     /locus_tag="VXB18_000245"
     CDS             complement(22912..23943)
                     /locus_tag="VXB18_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0381531.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDAYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24198..24881)
                     /locus_tag="VXB18_000246"
     CDS             complement(24198..24881)
                     /locus_tag="VXB18_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0381532.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDIDCSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24893..25837)
                     /locus_tag="VXB18_000247"
     CDS             complement(24893..25837)
                     /locus_tag="VXB18_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0381533.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25969..28800
                     /gene="uvrA"
                     /locus_tag="VXB18_000248"
     CDS             25969..28800
                     /gene="uvrA"
                     /locus_tag="VXB18_000248"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0381534.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVVEKIQKDGYVRVRVDGEVYDVTEVPDLSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDSSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVEMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVNNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGENGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28793..29854
                     /locus_tag="VXB18_000249"
     CDS             28793..29854
                     /locus_tag="VXB18_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0381535.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29986..30384
                     /gene="spx"
                     /locus_tag="VXB18_000250"
     CDS             29986..30384
                     /gene="spx"
                     /locus_tag="VXB18_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0381536.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30450..31019
                     /locus_tag="VXB18_000251"
     CDS             30450..31019
                     /locus_tag="VXB18_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0381537.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31106..31372
                     /locus_tag="VXB18_000252"
     CDS             31106..31372
                     /locus_tag="VXB18_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0381538.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31376..31795
                     /gene="ruvX"
                     /locus_tag="VXB18_000253"
     CDS             31376..31795
                     /gene="ruvX"
                     /locus_tag="VXB18_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0381539.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31811..32116
                     /locus_tag="VXB18_000254"
     CDS             31811..32116
                     /locus_tag="VXB18_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0381540.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32371..33621
                     /locus_tag="VXB18_000255"
     CDS             32371..33621
                     /locus_tag="VXB18_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0381541.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGDLAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33618..34163
                     /locus_tag="VXB18_000256"
     CDS             33618..34163
                     /locus_tag="VXB18_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0381542.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            34309..35841
                     /gene="cls"
                     /locus_tag="VXB18_000257"
     CDS             34309..35841
                     /gene="cls"
                     /locus_tag="VXB18_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0381543.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            35919..36062
                     /locus_tag="VXB18_000258"
     CDS             35919..36062
                     /locus_tag="VXB18_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381544.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36099..37637
                     /locus_tag="VXB18_000259"
     CDS             36099..37637
                     /locus_tag="VXB18_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0381545.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37757..39964
                     /gene="nrdD"
                     /locus_tag="VXB18_000260"
     CDS             37757..39964
                     /gene="nrdD"
                     /locus_tag="VXB18_000260"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0381546.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALRKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            39976..40116
                     /locus_tag="VXB18_000261"
     CDS             39976..40116
                     /locus_tag="VXB18_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381547.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40160..40666
                     /locus_tag="VXB18_000262"
     CDS             40160..40666
                     /locus_tag="VXB18_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381548.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40659..41249
                     /gene="nrdG"
                     /locus_tag="VXB18_000263"
     CDS             40659..41249
                     /gene="nrdG"
                     /locus_tag="VXB18_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0381549.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41246..41863
                     /locus_tag="VXB18_000264"
     CDS             41246..41863
                     /locus_tag="VXB18_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0381550.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42129..42437
                     /gene="rpsJ"
                     /locus_tag="VXB18_000265"
     CDS             42129..42437
                     /gene="rpsJ"
                     /locus_tag="VXB18_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0381551.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42654..43280
                     /gene="rplC"
                     /locus_tag="VXB18_000266"
     CDS             42654..43280
                     /gene="rplC"
                     /locus_tag="VXB18_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0381552.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43305..43928
                     /gene="rplD"
                     /locus_tag="VXB18_000267"
     CDS             43305..43928
                     /gene="rplD"
                     /locus_tag="VXB18_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0381553.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            43928..44224
                     /locus_tag="VXB18_000268"
     CDS             43928..44224
                     /locus_tag="VXB18_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0381554.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44242..45075
                     /gene="rplB"
                     /locus_tag="VXB18_000269"
     CDS             44242..45075
                     /gene="rplB"
                     /locus_tag="VXB18_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0381555.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45179..45460
                     /gene="rpsS"
                     /locus_tag="VXB18_000270"
     CDS             45179..45460
                     /gene="rpsS"
                     /locus_tag="VXB18_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0381556.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45472..45816
                     /gene="rplV"
                     /locus_tag="VXB18_000271"
     CDS             45472..45816
                     /gene="rplV"
                     /locus_tag="VXB18_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0381557.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45829..46482
                     /gene="rpsC"
                     /locus_tag="VXB18_000272"
     CDS             45829..46482
                     /gene="rpsC"
                     /locus_tag="VXB18_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0381558.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46486..46899
                     /gene="rplP"
                     /locus_tag="VXB18_000273"
     CDS             46486..46899
                     /gene="rplP"
                     /locus_tag="VXB18_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0381559.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46909..47115
                     /locus_tag="VXB18_000274"
     CDS             46909..47115
                     /locus_tag="VXB18_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0381560.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47140..47400
                     /gene="rpsQ"
                     /locus_tag="VXB18_000275"
     CDS             47140..47400
                     /gene="rpsQ"
                     /locus_tag="VXB18_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0381561.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47426..47794
                     /gene="rplN"
                     /locus_tag="VXB18_000276"
     CDS             47426..47794
                     /gene="rplN"
                     /locus_tag="VXB18_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0381562.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47872..48177
                     /gene="rplX"
                     /locus_tag="VXB18_000277"
     CDS             47872..48177
                     /gene="rplX"
                     /locus_tag="VXB18_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0381563.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48201..48743
                     /gene="rplE"
                     /locus_tag="VXB18_000278"
     CDS             48201..48743
                     /gene="rplE"
                     /locus_tag="VXB18_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0381564.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48761..49030
                     /gene="rpsN"
                     /locus_tag="VXB18_000279"
     CDS             48761..49030
                     /gene="rpsN"
                     /locus_tag="VXB18_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0381565.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49315..49713
                     /gene="rpsH"
                     /locus_tag="VXB18_000280"
     CDS             49315..49713
                     /gene="rpsH"
                     /locus_tag="VXB18_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0381566.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49905..50441
                     /gene="rplF"
                     /locus_tag="VXB18_000281"
     CDS             49905..50441
                     /gene="rplF"
                     /locus_tag="VXB18_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0381567.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50525..50881
                     /gene="rplR"
                     /locus_tag="VXB18_000282"
     CDS             50525..50881
                     /gene="rplR"
                     /locus_tag="VXB18_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0381568.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50899..51393
                     /gene="rpsE"
                     /locus_tag="VXB18_000283"
     CDS             50899..51393
                     /gene="rpsE"
                     /locus_tag="VXB18_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0381569.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51365..51589
                     /gene="rpmD"
                     /locus_tag="VXB18_000284"
     CDS             51365..51589
                     /gene="rpmD"
                     /locus_tag="VXB18_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0381570.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            51734..52174
                     /gene="rplO"
                     /locus_tag="VXB18_000285"
     CDS             51734..52174
                     /gene="rplO"
                     /locus_tag="VXB18_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0381571.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52187..53497
                     /gene="secY"
                     /locus_tag="VXB18_000286"
     CDS             52187..53497
                     /gene="secY"
                     /locus_tag="VXB18_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0381572.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53648..54286
                     /locus_tag="VXB18_000287"
     CDS             53648..54286
                     /locus_tag="VXB18_000287"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0381573.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAQALDKTLA
                     ELGIELEGVINIEVNPNSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54403..54621
                     /gene="infA"
                     /locus_tag="VXB18_000288"
     CDS             54403..54621
                     /gene="infA"
                     /locus_tag="VXB18_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0381574.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54646..54762
                     /gene="rpmJ"
                     /locus_tag="VXB18_000289"
     CDS             54646..54762
                     /gene="rpmJ"
                     /locus_tag="VXB18_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0381575.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54780..55145
                     /gene="rpsM"
                     /locus_tag="VXB18_000290"
     CDS             54780..55145
                     /gene="rpsM"
                     /locus_tag="VXB18_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0381576.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55163..55546
                     /gene="rpsK"
                     /locus_tag="VXB18_000291"
     CDS             55163..55546
                     /gene="rpsK"
                     /locus_tag="VXB18_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0381577.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55589..56524
                     /locus_tag="VXB18_000292"
     CDS             55589..56524
                     /locus_tag="VXB18_000292"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0381578.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56536..56922
                     /gene="rplQ"
                     /locus_tag="VXB18_000293"
     CDS             56536..56922
                     /gene="rplQ"
                     /locus_tag="VXB18_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0381579.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57187..57453
                     /locus_tag="VXB18_000294"
     CDS             57187..57453
                     /locus_tag="VXB18_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0381580.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAIVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57463..58800
                     /locus_tag="VXB18_000295"
     CDS             57463..58800
                     /locus_tag="VXB18_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0381581.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59044..59736
                     /locus_tag="VXB18_000296"
     CDS             59044..59736
                     /locus_tag="VXB18_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0381582.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59839..61474)
                     /locus_tag="VXB18_000297"
                     /pseudo
     CDS             complement(59839..61474)
                     /locus_tag="VXB18_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(61464..62087)
                     /locus_tag="VXB18_000298"
     CDS             complement(61464..62087)
                     /locus_tag="VXB18_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381583.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTIRDSVYLGLNTDYFIETGFASK
                     IQVSEESTFEEDLQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(62073..62195)
                     /locus_tag="VXB18_000299"
                     /pseudo
     CDS             complement(62073..62195)
                     /locus_tag="VXB18_000299"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(62172..62542)
                     /locus_tag="VXB18_000300"
                     /pseudo
     CDS             complement(62172..62542)
                     /locus_tag="VXB18_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62555..63571)
                     /locus_tag="VXB18_000301"
     CDS             complement(62555..63571)
                     /locus_tag="VXB18_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0381584.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKVELIQAGTGELFKKLESEKEVPVADVIFGGSYTQYTTHGELFENYTS
                     KENDNVIKEYQNTTGYSTPYTLDGSVLIVNPDLTKGMNIEGYNDLFKPELKGKIATAD
                     PANSSSAFAQLTNMLQAQGGYKDDKAWSYVKDLFTLIDGKIGSSSSSVYKVVADGEMA
                     VGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQE
                     VQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDI
                     QSKQ"
     gene            complement(64158..64934)
                     /locus_tag="VXB18_000302"
     CDS             complement(64158..64934)
                     /locus_tag="VXB18_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0381585.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65056..65802
                     /locus_tag="VXB18_000303"
     CDS             65056..65802
                     /locus_tag="VXB18_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0381586.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65815..66795
                     /locus_tag="VXB18_000304"
     CDS             65815..66795
                     /locus_tag="VXB18_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0381587.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            66990..67310
                     /locus_tag="VXB18_000305"
     CDS             66990..67310
                     /locus_tag="VXB18_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0381588.1"
                     /translation="MEMIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67356..67664
                     /locus_tag="VXB18_000306"
     CDS             67356..67664
                     /locus_tag="VXB18_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0381589.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67681..68979
                     /locus_tag="VXB18_000307"
     CDS             67681..68979
                     /locus_tag="VXB18_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0381590.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69130..71568
                     /locus_tag="VXB18_000308"
     CDS             69130..71568
                     /locus_tag="VXB18_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0381591.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71587..72255
                     /locus_tag="VXB18_000309"
     CDS             71587..72255
                     /locus_tag="VXB18_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0381592.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72273..73361
                     /locus_tag="VXB18_000310"
     CDS             72273..73361
                     /locus_tag="VXB18_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0381593.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        22240 a        13325 c        16088 g        21740 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgcggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttggc ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt
      661 tcagattatg caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc
      721 ggtgtccttc tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac
      781 gctacttggt tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag
      841 ttattttctc tggcttggtg acttggattc tccgtatgat tcccttcatc ttagtcaagt
      901 ataagggctt gccggcaatc gttgagcgtt ttttgaagtt cttgcccgtt tccattatct
      961 ttgccctgat tctttcaagc gtagtgacag gtaaggttgg cagtcttcct caaatcaaat
     1021 gactggactt cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag
     1081 tcggaacagt tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta
     1141 cccataaaaa aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc
     1201 tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac
     1261 tcatctcttg cagcccttgc tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt
     1321 gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca
     1381 ccaaagccat ttatctatga agaaaatggc gaattgactg gttatgagat tgaagtcgtt
     1441 cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca
     1501 ggtgtctttg ctggtcttga cgctgatcgt tacaatatgg ctgtcaacaa tcttagctac
     1561 actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc
     1621 cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg
     1681 acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa tgctgaacac
     1741 acggacaacc caactatcct taactatact aaggcagact tccaacaaat catggtacgt
     1801 ttgagcgatg gacaatttga ctataagatt tttgataaaa tcggtgttga aacagtgatc
     1861 aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac
     1921 gtttacccac ttcttgctca gggtcaagat gagttgaaat cgtttgtaga caaacgcatc
     1981 aaagaacttt ataaagatgg aactcttgaa aaattgtcta aacaattctt cggagacact
     2041 tatctaccgg cagaagctga tattaaataa tttcttgaaa tcatccattc tgagtaaggt
     2101 gggtggtttc tcagttttta gggatatagt tttaaactat atatctgact atctaataac
     2161 aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga
     2221 atcatgaaaa tcaaaaaatg gcttggtcta gcagcccttg ctacagtcgc aggtttggct
     2281 cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca
     2341 actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa
     2401 aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca
     2461 actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg
     2521 aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc
     2581 ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca
     2641 aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt
     2701 caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac
     2761 atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt
     2821 tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg
     2881 gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac
     2941 atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta
     3001 atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg
     3061 gatcaaccag tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt
     3121 ttgtatagag cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg
     3181 gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat
     3241 tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga
     3301 ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag
     3361 attgatgaga gctatacagc gccctttgta atggcacatt tcaagagttc gcgtccagat
     3421 gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc
     3481 tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt
     3541 gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac
     3601 catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca
     3661 acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg
     3721 gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag
     3781 gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat
     3841 ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct
     3901 gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga
     3961 gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat
     4021 ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc
     4081 gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact
     4141 attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg
     4201 catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa
     4261 ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc
     4321 aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca
     4381 gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc
     4441 ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat
     4501 tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat
     4561 caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatca cagcggttaa
     4621 ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat attctggagc
     4681 agggaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat
     4741 taccattgac gacgatgtga tttttgatgg taaggtcacc ttgacggcag agcagttgcg
     4801 tcgtaaacgt caagatatcg ggatgatttt ccagcatttt aacctgatga gtcaaaagac
     4861 agcagaggag aatgtagcct ttgcccttaa acactctgga ctcagcaagg aagaaaagaa
     4921 ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc
     4981 ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga
     5041 tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gaccctaaga caaccaagca
     5101 gattttggcc ttgttgcaag atttgaacca aaaattagga ttgacagttg tcttgattac
     5161 gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca
     5221 tttgattgaa gagggaagtg tccttgaaat cttctcaaac cctaaacaac ctttgactca
     5281 agactttatc tcaacagcca caggtattga cgaagccatg gtcaaaatcg agaagcaaga
     5341 aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc
     5401 aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct
     5461 ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggttttgtc
     5521 aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact
     5581 aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg
     5641 tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt
     5701 atatgacagt tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc
     5761 tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca
     5821 aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac
     5881 tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt
     5941 ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg
     6001 gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc
     6061 tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg
     6121 gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt
     6181 atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccatcatt atcattttga
     6241 ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagc cataaataaa
     6301 aaagagccgt gtggctcttt ttaactgatc agattttctg ggcaaatttt ttactcaagg
     6361 cttgtccaat caaggcaccc actagggctc cgatgacaat acttgcgata aatagaagga
     6421 cagttccagg gtttggagtg accatgatac ggtcgatata ttcttgggat tttcctcttg
     6481 ccagaagagt agccatatag gctttgggcg caatccacat aagcaagatt ggtcctgttg
     6541 tactaaaggc gaaaataatg aaagaaagga agttctttgt tttgtccttg tattttccta
     6601 aatgagctac ttcatctgct aggaggccac agataattcc aggaaggaag gaaccagcac
     6661 cgtgtttagt tcccaagaaa aagaaggcaa tgacaaggcc gatagtggta atggctccaa
     6721 agcgcggaac ttttgcgact aggatcatat agacgctacc gccgacaagg gcagtaaagg
     6781 caggcgcata aaacatgttt ccagtttggt caaagagatt gcccaaaagg acaccaatcc
     6841 ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt taagatagat tttttcatga
     6901 attgtctcct gataattttt tcacaattct cattgtacca cggtttggtg ggattgtaaa
     6961 tggatactag aagtttttga aaacgcttga aatatgatat aatggtttca tagttatttt
     7021 taggggaata tcatgggtag atttttagac tttgtcttta atcgtttctt tttagggatg
     7081 attgcgacag ccttcttttg gctattaact ttagcaggag ggattatcct tggtctagcg
     7141 ccggctagtg ccaccttgat gagcttatat gcagaacatg gttatagctt tcgggaatac
     7201 agtttgaagg aggcttggtc tctttacaag caaaattttg tctcaagcaa cctgattttc
     7261 tatagctttt taggtgtggg tctagttttg acctatggtt tgtatctctt ggtgcaattg
     7321 cctcatcaga ccattgttca tttgattgcg acccttttga atgtcctagt agttgccctg
     7381 atctttttgg cttatacagt atctttaaaa ttacaagttt attttgcctt gtcctatcga
     7441 aatagtctca aattatcctt gattggcatc tttatgagtc tagcagctgt ggccaaggtt
     7501 ctccttggga ctgtgctact tgtagcaatt ggttactata tgcctgccct gctatttttt
     7561 gtaggaattg ggatgtggca tttctttatc agtgatatgt tggaacctgt ctatgaaatc
     7621 atccatgaaa aattggcgac aaaatagaat gaagcagttt tggctacata cgcttctaag
     7681 aacctatagt tcagtgatga tcattatcat tgcgagtttt gcaatcttac tctcttacgc
     7741 tgactgggat tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa ctgctagaac
     7801 agtgagtgaa attgaatatt accatagaga gtcaacccag atagctcagg ctttagttga
     7861 aaatcaagct cgtatcgagg gaatctataa atactttagc cttagcatgc cagactattt
     7921 ttactggcaa ttagagcgga aagcttcgcc ttatatatca gtctctctgt atgaaaatgt
     7981 tgatgacctc tatgttcgaa atgattttgt aactggggtg gccattgctt ttcaagatta
     8041 caaggaagtc tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca gggctgagga
     8101 tttcaaacca gcaggaaata gttttgccat tccagtgtca gatccagtgt cagatcaaga
     8161 cttaggagtg atttacatct ccttggatcc tgctgtttta taccatgcca ttgataatac
     8221 tagaggtcat actccgatgg cagtaacagt gacctcacct tttgatacgg agatttttca
     8281 tatgggtgag acagttgata aggagagtga aaattggcta gttggcttaa cttctcatgg
     8341 ttatcaggtt caggtggcag ttcccaaaaa ctttgtttta caaggaacgg tgaccagctc
     8401 tgctttgatt gtgggcttga gccttctctt tattgtcatt ctttatctga ctttgaggca
     8461 gacctttgct aattatcaaa agcaggtagt ggatttggtg gattccatcc aagctattgc
     8521 ccaaggacaa gaaggtcttc gcattgatac gcttgaaaag gatcaggaat tgctcctaat
     8581 cgcggagacg accaatgata tgttggatcg attggaaaag aatatccatg atatttacca
     8641 gttagaactc agtcaaaaag atgccaatat gcgggccttg caggcgcaaa tcaaccctca
     8701 cttcatgtat aatacgctgg agttcttgcg tatgtacgca gtcatgcaga gtcaagatga
     8761 gttggcagat atcatttatg aattcagtag tctcttgcgt aacaatattt ccgacgaaag
     8821 agagaccctc ctcaaacagg aattagaatt ttgccgtaaa tacagctatc tctgcatggt
     8881 tcgctatccc aagtccattg cctatggttt caagatagat ccagagttag agaatatgaa
     8941 gattcccaag tttaccttgc aaccgctggt agaaaactat ttcgcgcatg gtgttgacca
     9001 caggcggaca gataatgtga ttagcatcaa ggctcttaaa caggatgggt ttgtggaaat
     9061 tttggtggtc gataatggta gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa
     9121 attaagtcag aaatattttg aacaccaagc cagctacagt gatcaaaggc agtctatcgg
     9181 gattgtcaat gtacacgagc gttttgtgct ctattttgga gaccgctatg ccattactat
     9241 agagtctgca gagcaagccg gtgttcagta tcgtattaca attcaagatg agtagaaagg
     9301 gagaaaatgt ataaagtatt attagtagat gatgagtaca tggtgacaga aggtctgaag
     9361 cgtttgattc cctttgataa gtgggatatg gaggtcgtcg caacagccag tcatgccgat
     9421 gaagctctag aatatgttca ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg
     9481 ccagacaaaa cagggcttga tatgattcgg gagatgaaag agatcttacc agatgctgcc
     9541 tatatcctgc tctcaggtta tcaggagttt gattatgtaa aaagagcaat gaaccttagt
     9601 gtggtggact atttggtcaa gcctgttgat aaggtagagc tgggaaatct gctggagaag
     9661 attgcaggtc agctcggcga gagagggaag aaaagtcaga ctcttagtca agaattagac
     9721 gaggctggat ttgttagtta tttaggggat aaggagaatt ggtggatagg tctatccaag
     9781 gaaaaacaag gttccttcac cattccctac tatgtcttgg gccaagactg gcagattttc
     9841 atttctgacc aacccctaga tggtttagtc gttacacctt ttgaagctcc ttatcaagaa
     9901 cactttgaac gctggaagct gaatgctgag aaaaccctct tttacggttc tgtaaatttg
     9961 cagcagtctg agagtctctt tgcctattac gaaccgattt atagggttat tattcaggga
    10021 aatctcaatc aaatcgtaga agagttaaat ctcttggaga aggtagttct tgaaaatacg
    10081 ccgcgtgttc cgattactaa acagcttttt attcagtttg tcatggatgt tttccattta
    10141 tttgaacatc tcaaagctga tgacctgaca gacatcgtca aaaccattca tgctattcaa
    10201 tccttcgatg aattggttcc ttatatcaag gaaactctga gcagcttttt cggtcaatac
    10261 cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta ccaaaaagag
    10321 ctttccctca aggatatcag taaggctctc tttatcaatc ctgtctatct agggcagttg
    10381 attaagcgtg aaaccgattc gacttttgca gagttactaa acaaacaacg tattaaggct
    10441 gcccaacaac ttttgctttc aactagtgac agcatcgaag atatttgtta tgctgttggt
    10501 tacagtaacc ttggatattt ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa
    10561 gcctaccgaa aacaggtaga aactatacta taagatttgt attcctttac aaaaggtgct
    10621 ataatattat caggaggtcc tatcatgaaa aagaaaccaa tttatctatg ggttttgcta
    10681 atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc cttgcctagt
    10741 aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca gcaattagaa
    10801 gaccagctta attataccta tagagtagca gaagcatctc attctatttt taatgttgct
    10861 ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt tcgtaaaaat
    10921 ttgcaatatg caaactatac ttacgttggc tatgttttgt tagctattat tggttcgatt
    10981 tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag catgcgtttg
    11041 acagtgagta ttggttcaaa agctgttagc attttctata tcgtcatcaa tgttctcttc
    11101 ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga agaagaggaa
    11161 acagaagagc ttacctaagt attgacaaaa aagaactatc aagatacaat cttggtagtt
    11221 gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct ttagtttata
    11281 ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat ctcttgtccc
    11341 agtacaaagg gattgaggtt caaaagattc atatcaagga tttggtcaag gaaggcaaaa
    11401 atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc gaaggtggga
    11461 atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat tttattgcct
    11521 atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt aactttaata
    11581 accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct gtattggctg
    11641 actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt atcgcagatt
    11701 tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa actaggaagc
    11761 tagtcgcagg ttgctcaaag cacagctttg aggttgcaga tagagctgac gtggtttgaa
    11821 gagattctcg aatagtataa agttcttata agaggtggtt gaagttgttc aactgttttt
    11881 tgagtataaa cagtctttaa gaacgtaaaa aagcataagt tcaggtcttc aaaaccttgt
    11941 tcttatgctt tttatcatag aaatatttgc tgaattttct cttgaaatga aaccttatct
    12001 tcatctcgcg cttgtccctt accctgcttt tccgattgcg agtgcgtaga taaagaagat
    12061 ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc aagaaggaag
    12121 atttttgttt tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag gtgttgtcag
    12181 gaaagagcca atcatggcaa agcggagcat ggttgaaacc tgaccagcga agaacttgat
    12241 aatgacgata ccgatgatag cagtgatggt catccagatg ttcaaagatt tacgattgtc
    12301 ctctttttga ctgattagca gtcggagaga ttcctgatta acgcgagaat agccatcgat
    12361 aacagttata actgttccaa agatacagag gaaggcaata aaggtaatca agtaacggga
    12421 ccattcgcca agaacagagg catacatgcc cacgaattga gagatgtatt tggctgaagc
    12481 agcttcaacc gcctgccctg taggatactg aatcagtgct cccagtgcca caaagaagac
    12541 ggctaggata gctgttccaa tataaccagt gttaaagtca aacagagcgt cttctgtgtt
    12601 aaagttgacg gtctttctct tttcagctga ccaaagtgaa ttgatggctg aaatttcaat
    12661 aggagccggc atccatccta ggagggagac gatgaagggc agagctgcca tttgccaagg
    12721 tgtcttctcg acaaaatcag aactgtattc tggatgcttg accgccgcaa tgataactgc
    12781 aagaacagtc gcaatggtta aggcagacat aatccatttg accatgccgt ctaaaagttt
    12841 gtagcctcca aagagtagca tagcccaaat gattgcaacg agaatgaggg accactgagt
    12901 aatgctaagt ccaatcattg ggaaggcact ggcgatgata gctgagcaca gaatggcaac
    12961 accagccgtg ttgaccatag ccgaaaagac attgaggata aagaaaatcc agagatagag
    13021 ttttcctttt tcggcataac cttcaaccaa agtctttcca gtatcagctg tgtattcagc
    13081 accaaaacgg aaaaatggat atttaaagac attggctaag atgaccaaga gaagtagaga
    13141 ccaaccgtaa gaaccgccag cttgagttga ggatacaatg tgggaacctc caacagcggc
    13201 agttgccatt aggattccag gtcccattgc ttttagcttg cttgcccagg ttgattgatt
    13261 taaggaaata gcttgcgaca tgataaatac tcctttttga attttcagaa taatctgtat
    13321 atgtaatcta tattctacaa aaaattttgg aaaaatgcaa gagtattttg aaaaaagata
    13381 gaaaatttac aaagaaaatc tgaaataact gttatgatat agaggattga aactagaata
    13441 gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttatc
    13501 ctgttcttat ttcatttcac tatagtaagg tgcagcagga taaagaaaaa ccgagaagtt
    13561 tctttctcgg atttgcttat tatgaggttc ctattttcta tgctccaaga gttgattgat
    13621 gtgatctact tttttagcct ctcttttata gagaatagcc cagatgatga gatagacaat
    13681 cgcaaactcg ataatgagct ggaggtagaa aatccagtgg aaagggaacc aaccagcaag
    13741 agttgctagt gggacaaagc cagccagcat aaggaagaaa tgagtcagag tggcacgaag
    13801 catgctccag tcacggctaa ataagcggtt gccaaagttg aagagcatac cgatggttgc
    13861 ccagataagt gtgcagtaga gcaagaccag ggcaccgtga acctgatgct gatccatcac
    13921 ttggccgatg agagagtagg gatttagtgg tgcgtaggta tttggtgcat aaatgagtga
    13981 aaagaggata gagaggatga ggccgataag aacaccggta gctgcatcgt gaaatacttg
    14041 ttttttcata gttctaattt ctccttgatg gtttttagat aacggcgtga agagtaggtg
    14101 aagctttcgt ttttcaagaa aatttctacc agaccgtttg gcgtgagctt gaggtgagag
    14161 atggaatcga tattgatgat ttctgattgg gaaatttgga taaaattggt tggcaagagt
    14221 ttaagaacct gatagagtcg caaatcaatg ctgtaggtct gactcgcggt ttctgctaga
    14281 accttccgat tctcgatata gaagcgctga atcttgccaa tctcaactag atagacctga
    14341 tcatcgattt ttcctttgat tttttctctt tggtccagat tttctgcgaa ctcgatgact
    14401 ttctggactt tttcggtttc ttgaggtgct tggacaatca gcttttcctc ctcgtaagtc
    14461 tcactaatct gtagttctac tttcataaat ttctctcctt gtttttcata caaaattaat
    14521 ctcacttctt gtacaccttt attaatactc ttcaaaaatc tcttcaaatc acgtcagcgt
    14581 cgtcttgccg taggatagtt gttgactttg tcagttttat ctacaacctc aaaacagtgt
    14641 tttgaactgt ctgcgcctag ctttctagtt tgctctttga tttttattga gtataccact
    14701 attttactcc ctctggcaag ggactttgtc tatgtggagg gattgggctc ctatgtggtg
    14761 gagcttttct gttctttctg aaatatggta taatagcact aattaatttc taggaaaata
    14821 gatacagaaa ggggctgaaa gatgtctcat attattgaat tgccagagat gctggcaaac
    14881 caaatcgcag ctggagaggt cattgaacgt cctgccagtg tggtcaaaga gttggtagaa
    14941 aatgccattg acgcgggctc tagtcagatt attattgaga ttgaggaagc tggtctcaag
    15001 aaggttcaaa tcacggataa cggtcatgga attgcccacg atgaggtgga gttggccctg
    15061 cgtcgccatg cgaccagtaa gataaaaaat caagcagatc tctttcggat tcggacgctt
    15121 ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta gtgtcttgac tctgttaacg
    15181 gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc gtgggggtga agttgaggaa
    15241 gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg tggaggatct ctttttcaac
    15301 acgcctgccc gtctcaagta tatgaagagc cagcaagcgg agttgtctca tatcattgat
    15361 attgtcaacc gtctgggctt ggcccatcct gagatttctt ttagcttgat tagtgatggc
    15421 aaggaaatga cgcggacagc agggactggt caactgcgcc aagcaatcgc agggatttac
    15481 ggtttggtca gtgccaagaa gatgattgaa attgagaact ctgacctaga tttcgaaatt
    15541 tcaggttttg tgtccttgcc tgagttgact cgggctaacc gcaattatat cagtctcttc
    15601 atcaatggcc gttatatcaa gaacttcctg ctcaatcgtg ctattttgga tggttttgga
    15661 agcaagctta tggttggacg ttttccactg gctgtcattc acatccatat cgacccttat
    15721 ctagcggatg tcaatgtaca tccaaccaag caagaggtgc ggatttccaa ggaaaaagaa
    15781 ctgatggcgc tggtctcaga agctattgca aatagtctca aggaacaaac cttgattcca
    15841 gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc gtgagaaggt ggagcaaact
    15901 attctcccac tcaaagaaaa tacgctctac tatgagaaaa ctgagccgtc aagacctagt
    15961 caaactgaag tagctgatta tcaggtagaa ttgactgatg aagggcagga tttgaccctg
    16021 tttgccaagg aaaccttgga ccgattgacc aagccagcaa aactgcattt tgcagagaga
    16081 aagcctgcta actacgacca gctagaccat ccagagttag atcttgctag catcgataag
    16141 gcttatgaca aactggagcg agaagaagca tccagcttcc cagagttgga gtttttcgga
    16201 caaatgcacg ggacttatct ctttgcccaa gggcgagatg gactttacat catagatcag
    16261 cacgctgctc aggaacgggt caagtacgag gagtaccgtg aaagcattgg caatgttgac
    16321 cagagccagc agcaactcct agtgccctat atctttgaat ttcctgcgga tgatgccttg
    16381 cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg tctttctagc agagtacgga
    16441 gaaaatcaat ttattctacg tgaacatcct atttggatgg cagaagaaga gattgaatca
    16501 ggcatctatg agatgtgcga catgctcctt ttgaccaagg aagtttctat caagaaatac
    16561 cgagcagagc tggctatcat gatgtcttgc aagcgatcta tcaaggccaa tcatcgtatt
    16621 gatgatcatt cagctagaca actcctctat cagctttctc aatgtgacaa tccctataac
    16681 tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt cggatatgga aaagatgttc
    16741 cgacgtattc aggaaaatca caccagtctc cgtgagttgg ggaaatatta aaagtataaa
    16801 aaagtctggg aaaaattttc aaaatcagaa aaacgcataa aatcaggtgt tcaaaaacct
    16861 tgatttttat gcgttttatc atggaaatag ttacttcatt ttttcctaat tcttttcgaa
    16921 actcttttta aacgacgtca gttttatcag taatctcaaa acagtgtttt gagctaattt
    16981 tgccagtttt gtctgtaaca tcgaagttgt gttttaccac tctgcgactg gtttcctagt
    17041 ttgctctatg attttcacag agtattaaat tgcgattttg ccaagtttct ttattcgtct
    17101 aaaagtagag tctgttctat gcgtctaatg tacgaattag gttgaccatt tcaatagctc
    17161 cttgtgcaca ctcagaaccc ttatttcctg ctttggtacc agctcgttct atggcttgtt
    17221 caattgtatc tgtcgttagc acaccaaaca taacaggaat ttcgctattt aaactgattt
    17281 gggcgattcc cttagatacc tcgctacata cataatcata atgacttgta ttccctctaa
    17341 tgacagctcc caagcagata attgcatcat attttttact ttttgccatt tttgatgcaa
    17401 tcagtggtat ttcaaaagct cctggaaccc aggctacctc gatatctttc tcgtttacat
    17461 tctctctttt gagattatct agtgctccag ataataattt tgaagttata aattcattaa
    17521 atctcgctac aacaatacct attttaatat tgtttgctac taaattacct tcataagtgt
    17581 tcatttattt ttcctccata tttaaaatgt gacccattcg atttttcttt gtttctaaat
    17641 aaaaactatt gtaaggattg gcttctattt cgattgatat tctactggaa atggtaattc
    17701 catatttttc taactgttca accttgtcag gattatttgt cagtaaatga agtgactgaa
    17761 gtcccagatc tttaagcatt tgtgctccaa tatgatattc tcttaaatca ccttcaaagc
    17821 ctaatgcaag attagcatca agcgtatcca tgccttgatc ttgtaaatga taggctttta
    17881 atttattgat aagtccaatt cctcgtccct cctgtcgcaa gtaaagtaag acacccgaac
    17941 cattctcaac aatcattttc atagctttat cgaattgctg tccacaatcg caacgtaaag
    18001 agcctaaaat atcccctgtt aaacattcgg agtggacccg acataataca ttggcttcat
    18061 cctctatgtt tcccataata agagcaagat gatgttcccc atttagttta tctatatagc
    18121 taattgcttt gaaattaccg tatctagtag gcatattgac agttgaaact cgttctacca
    18181 gctgatcata tacttttcta tattcttgta attctttgat ggtaattagt ggaatgttgt
    18241 gtttcttcga gaactgaatt aaatcatctg ttctcatcat tttgccatca tgattcatta
    18301 tttcacaaca taggccacac tcttttagtc cagctaattt taataaatca acagttgctt
    18361 ctgtgtgtcc atttctttct aggacaccac ctttttttgc aattaaagga aacatgtgtc
    18421 ctggcctgcg aaaatcagag ggtgttatat cttcagctac acacatacgt gcggtcagtc
    18481 ctctttcctc ggcagaaata cctgtggtcg tttctttata atcaattgaa actgtaaaag
    18541 cagtcttatg attatctgta ttgttttcaa ccataggtga aagcattaat tgattagcta
    18601 aactttcgct cataggcata caaattaatc ctttggcata agtagccata aaattaacat
    18661 tttctgttgt agctgcttgt gcagaacaaa ttaagtctcc ttcattttct ctatccttgt
    18721 cgtctataac aagaacaagt cgtcccttct gcaatgcttc taatgcttct tgtatttttc
    18781 gatattccat tgactaatta tcctttctgc taaaatccat tttgatataa tagttcctta
    18841 gatatttctg attttggaga gttatccatc agtttttgca catatttacc taagatatca
    18901 ttttcaagat ttactgtact cccgacttgt ttactcttaa gaatggtttg ttccaaggta
    18961 tgagggataa cagatactga aaagtttact ttggagactt tagcgacagt cagactaatg
    19021 ccgtcaattg taatagatcc tttttcaact attaaatcta aaatttcttt ttgtgtgttg
    19081 atttgatacc atacagcatt atcatctttt tttattgacg agatttttcc tgtaccatca
    19141 atgtgtcctg taacgacgtg acccccaagt cgaccgttga cagataaggc tctttctaga
    19201 ttcacctcac ttccatgttt taatagagta agagctgttc gactccatgt ttcattcatt
    19261 acatcaactg taaaggattg atgattgaaa tgagtaactg taagacagat accatttact
    19321 gctatactat cgcctaaatg gatatccgtt aatatttttg aggctttaat tgatagttta
    19381 caattacgag agtctttctg tattctttca acttttccga tttcttcaat tattcctgtg
    19441 aacatggata aatcacttca ctttctatga gatagtcatt tcctatttga gaaaaagtat
    19501 aaggtttcaa tctaatagcg tcatttggca aagaaatgcc ttcacctccg acaggaaact
    19561 tggcactgcc tccaaaaatt tttggtgcaa tatatatttt cagctcatca acaatttgtt
    19621 gttccaaagc actccaattc attagactgc ccccttctag aactaggcta tcaatctgca
    19681 tgtttcctag atgttgcatt aaactcgata agtctatatg attgcctttt ttctttatgg
    19741 aaagtatttc acagccatga ttttgatata gcttcatttt atttttgtct tcagaggaag
    19801 tggcaatgta agttttaata tcatttgctg tttttacgat tttagaggta agaggagttc
    19861 gtaaatgtgt atcgcatatg atacggatag gatttttccc ttcctccaat ctacatgtca
    19921 gcaaaggatc gtcttgaata acagtattga ctcccaccat aattgcacta acatggtgtc
    19981 gtaactgatg cacgtgcttt cttgcttctt cttcagtaat ccatttggat tgatttgttt
    20041 tagtggctat ttttccatcc attgacattg catatttcat aaaaacatag ggtacatgct
    20101 gggtaatata ctttctaaaa ctttttatta agttaagaca ctcattttct aaaattccaa
    20161 cagtaacttg aagattattt tcctcaagta tctttactcc ttttccagat acaataggat
    20221 tacagtctag gcttccaatg actactcttg taataccact atcgattata gcatctatac
    20281 agggaggtgt tttcccgaag tgacaacagg gttcaagtgt tacataaagc gtcgctccga
    20341 caggggattt tctacagttt ttaagagcat ttctctcagc atgtgggcca ccaaaaaact
    20401 catgataacc ttgtccgata atgtgattat cttttacaat aattgcgccg accataggat
    20461 tggggttgac gtaaccagcc cctttttgtg ccaattttat tgctaatttc atatattttg
    20521 aatcgctcat ctcgctacct ccaaaaaaat ataccttgaa taggggacta ctcaaggcat
    20581 acaaaagaaa acttatgcga ttaacaaaaa tgctctgaaa tgacaagtaa tcatttcaga
    20641 gcacgcaaaa agcacaaata tacttttatc ttctttcatc cagactatac tgtcggcttt
    20701 ggaatttcac caaatcatgc ctttcggctc gtgggctata ccaccggtag ggaattgcac
    20761 cctgccctga agatagttat tcaattacag atgattatag tacttaattt tgaatatgtc
    20821 aacagataaa taccgattgt ttttgatata ctgtatttgt gataatcgat tctcgctcct
    20881 cggataaaga aaatatgata tactagataa acgaaataag agagaaggaa cactatgtac
    20941 gcatatttaa aaggaatcat taccaaaatt actgccaaat acattgttct tgaaaccaat
    21001 ggtattggtt atatcctgca tgtggccaat ccttatgcct attcaggtca ggttaatcag
    21061 gaggctcaga tttatgtgca tcaggttgtg cgtgaggacg cccatttgct ttatggattt
    21121 cgctcagagg atgagaaaaa gctctttctt agtctgattt cggtctctgg gattggtcct
    21181 gtatcagctc ttgctattat cgctgctgat gacaatgctg gcttggttca agccattgaa
    21241 accaagaaca tcacctactt gaccaagttc cctaaaattg gcaagaaaac agcccagcag
    21301 atggtgctgg acttggaagg caaggtagta gttgcaggag atgaccttcc tgccaaggtc
    21361 gcagtgcaag caagtgctga aaaccaagaa ttggaagaag ctatggaagc catgttggct
    21421 ctgggctaca aggcaacaga gctcaagaaa atcaagaaat tctttgaagg aacgacagat
    21481 acagctgaga actatatcaa gtcggccctt aaaatgttgg tcaaatagga gcagagaatg
    21541 acaaaacgtt gttcgtgggt caagatgacc aacccgctct acatcgccta tcatgatgag
    21601 gagtggggcc agcccctcta tgatgaccaa gcattgtttg agttgttgtg tatggaaacc
    21661 tatcaggcag gcctgtcttg ggaaacggta ctcaacaaac gccaagcttt ccgagaagcc
    21721 tttcatagct atcaaattca ctcagtcgca gagatgactg acactgaatt ggaagccatg
    21781 ctggagaatc cagctatcat tcgaaataga gccaagattt ttgctacacg cgctaacgcc
    21841 caagcttttc tacagttaca ggcagagtac ggctcttttg atgcctatct ttggtctttt
    21901 gttgagggga aaactgtcgt taacgatgtt cctgattatc gccaagcccc agctaaaaca
    21961 cccttatctg agaaattagc caaagatctc aaaaaacgag acttcaagtt cacaggccca
    22021 gtcgccgtat tgtcttttct acaggctgca gggctagttg atgaccacga gaatgattgt
    22081 gagtggaaag gtcttaaatg atgtctaaca aaaataaggg aattctgatt tttgcgattc
    22141 tctatacaat cctctttgtg tttgatggcg ttaaattgct ggcttcttta atgccatctg
    22201 ccattgcaaa ttatcttgtt tatgtagttt tagctttata tggctccttc ttgttcaagg
    22261 atagattgat ccaacaatgg aaggagatta gaaagactaa aagaaaattc ttctttggcg
    22321 tcttaacagg atggctcttt ctcattctga tgactgttgt ctttgaattt gtatcagaga
    22381 tgttgaagca gtttgtggga ctagatggac aaggtctaaa tcagtctaat attcaaagta
    22441 cctttcaaga acaaccacta ctgatagctg tttttgcttg tgtcattgga cctctggtag
    22501 aagaattatt tttccgtcag gtcttattgc attacttgca ggaacggttg ccaggtttac
    22561 taagcattat tctggtagga cttgtttttg ctctgactca tatgcacagt ttggctctat
    22621 cagagtggat tggtgcagtt ggttacttag gtggaggcct tgccttttct attatttatg
    22681 tgaaagaaaa agagaatata tactatcccc tacttgttca catgttaagc aacagcctct
    22741 ccttaatcat tttagctatc agtatagtaa aatgaaatga gaacaggaca aatcgatttc
    22801 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatatattgt aatatgtgat
    22861 gaaaatgcca gtaatgatac cgagaaaaaa gctgagaaac ttttcccagc tttatttgtt
    22921 atagtcaaag agaatgactt gttcctgtgc atctacatga gcatggaccc caaagggtac
    22981 aattgctctt ggagttgcgt ggccgacatt cagattatag acaatcggga tattgctgtc
    23041 aatgatatcc aatagtgcct ctttatagtc gtcatggaaa gtttcatcca taggttttcc
    23101 gaccaagagt ccattgatga ccgcgaatat gccagtgtcc tttaaagtta gcaacatctt
    23161 tttgaagtct tctggcttag gcttttcttc gcttgtttcg agcaagagga ttttcccttc
    23221 ccagtctgac aagtcaggga aaagtttgta tttttggcag agttccgtgc tatctgcgta
    23281 tcgagagttg tcaaagatat cgtagaggga ttcgaggcaa ccaccgagga ttttcccctc
    23341 gaactgggca cttccttgca acaagtcaaa acctgtattt gtatgactga cacgaggtgt
    23401 tcccagggcc gtgggactaa aatcagttcg ttcctcatac caaacgtcac tagggcggat
    23461 ttctgaaatt cttcccgtct caatcaattc tttaaagtag tgaaggctat aggctagcat
    23521 ttctttgtct aattcacaaa tgtctgctaa aaaggattga ccataaaaag tcttgattcc
    23581 taatttatgc aacatgaggt ggttcatggt tgtatccgag aagccaagaa aaattttttg
    23641 tttgataacc ttttggagtt ggtcattttc aaaaagataa ggtagcaagc gataggcatc
    23701 gtctccaccg atggcacata ggatcatgtc gatgctatca tcagaaaagg catgaatcaa
    23761 atcctctgca cgagcttcag gatggtcctt gataaagtct aatcctttta acgaatgggg
    23821 caaaaagatg ggattgagtc ccagatcctt gagacgttgg atacccaagt ccacttcgtg
    23881 tttgacaaaa tcctctccga taatgccact agataaacta acaataccaa tagtagaaac
    23941 catatctcat cctcctagaa atagattgag cctattttat cacaaaatat aagagaaagc
    24001 tatgtgggat ttcagaagaa tacttttaat actcttcgaa aatctcttca aaccacgtca
    24061 gttttatttg caacctcaaa gctgtgcttt gagcaacctg cagctagctt cctagtttgc
    24121 tctttgattt tcattgagta taactcaaaa aagtaagtga aaaagcaacc gcacctgcag
    24181 ttgcttttat cgttttctta ttcttgatag cgtgttggtc ctgcacttgc actacggata
    24241 ttcaagcgtt tcttgagata gaagcgaagg gctaggaggg ctgctccaat aatagctagt
    24301 ggcaatggat ccagtactgg gttaaggcta gctggtagga agcttgttgc aaagaagaca
    24361 agcaaccaaa ggaacataga agctaggata actagtacag atttccagaa aggtggacgt
    24421 tgactgcaat ctatatctgg tccatagtat tggtaaacaa agtagtacat caagtagaag
    24481 gcaaatccac caaccagtcc aactaataga agagtaatca atccatagcc gaaagcttga
    24541 tctgccgcaa agaaggttgt gagggcgctg acaagggcaa agaggctagt gatgaaaaga
    24601 gctgagtcca taatcatcag ttttggatca tcattttctt ttggatgctc tttttcgtac
    24661 tgctctttga cagtgaagct atgagcccaa tgagttggtg cgccgtatag ggaacgggca
    24721 gttgtacctt tagattgctc ctcaaggatt tggggaatga cttcctcaaa aatagtctgg
    24781 atttcagcgt ctgttttccc atctttgatg aattgttggg tagcaatgtg gacaaactct
    24841 tggtttttct tagttaattt ttgtagatca atttgagaca taggaactcc tcttagaacc
    24901 attttttatg gatgagatag agagtgagcg agacactcat agcaaaggcg ataaagacga
    24961 ttaaccagaa ggcatttggc tctccgttta gggggatttc attatcctta aagttcatcc
    25021 cgtaggcaga aaagaccatg gttgggatgg acatgacgat ggtcacaagg gccaaggttt
    25081 tcatgatgtt gttctggttg ttagaaatga tagaggcaaa ggtctctgtc atagaatgca
    25141 agacgtttcc ataaatatct gccatctcga tggcctgttg ggtttcaatc agggtgtctt
    25201 caagcaggtc ttcgtcctca aggtatttct tgatattgct ggttgaactg gtcaatttct
    25261 taatcacgcg ctcatttgtt ttgagggagg ccttgaaata gacgatagtt ttttccaatt
    25321 ccatgagctc aatcaattct tcattacgag ttgattgatg cagttgactt tcgatttgtt
    25381 cactcttgcg gtcgattgaa cgaagggctg ttaggtaaag ctctgcattg cgataaagaa
    25441 tttgaaagat aaaacgtgaa cgcatgaagg tatagaaatt acgcaatcga cggttgataa
    25501 agacatcaag gacaggtagt ggttccaaac acgtagtgat aatggtttcc tcagtgatga
    25561 taataccaag cgggatggtt acgtagtagg tgcggttatt tctttcctcc gtgaccggca
    25621 cgtctacgat aatcagggta tactcgtctt caatggtaat acgagacatt tcttccgcat
    25681 cgagcggtgc tcgaaggtcg gcaatatcaa tatcgaaggt gttggcgatt tcgagtgatt
    25741 cattttgagt cggattgacg agattgatcc aagtacccgg ttcaagcgta tcgatctctt
    25801 taaattcagt tgttgtagag agaaaaactt gtttcatatc ccttatcctt tctcattttt
    25861 cagatttttt cacactgtac tattatacta caaaatcggc cttttgggta atagaatctc
    25921 actttttttg gtataatggt aagcaataat ggactagaaa gaacaaagat gcaagataaa
    25981 attgtcattc atggggcgcg tgcccataat ttaaaaaata ttgatgtgga gattccgcga
    26041 gacaagctgg ttgtcgtgac aggtttgtca ggttcaggga aatccagtct ggcctttgat
    26101 accctctatg cggagggaca acgtcgctat gtagagagtt tgtcagccta tgctcgtcaa
    26161 ttcttgggaa atatggagaa gccggatgtg gatgccattg atggtctcag cccagctatt
    26221 tctatcgacc agaaaacgac tagcaaaaac cctcgctcga cggtgggaac aacgactgaa
    26281 atcaatgact atctgcgtct cctctacgcg cgtgtgggga cgccttactg tatcaacgga
    26341 catggagcta tcaatgcttc ttctgtggag caaatcgtgg ataaggtctt ggaactgcca
    26401 gaacgtcagc gcctgcaaat cttagctcct gtcatccgca agaaaaaagg acagcacaag
    26461 agcgttgttg aaaagattca gaaagatggt tatgttcgtg tccgtgtgga tggggaagtc
    26521 tatgatgtga ccgaagtgcc agacttgtcc aagagcaagc aacacaatat cgatgtcgta
    26581 gttgaccgta ttgttatcaa ggagggtatc cgtagtcgtc tctttgattc cattgaggct
    26641 gcccttcgta ttgcagaagg ttatgtcatt atcgatacta tggacagttc tgagttactc
    26701 ttctctgagc attatgcttg tccagtttgt ggatttactg tcccagagtt agagcctcgt
    26761 ctcttctctt tcaatgctcc ttttggctct tgtagtgagt gtgatggctt gggcatcaag
    26821 ctggaggtgg atactgattt ggtagtacca gatgccagca aaaccttacg tgagggggcg
    26881 ctagcacctt ggaatcctat ttcatccaac tactatccaa atatgctaga gcaggccatg
    26941 acagcctttg gagtggagat ggataagcct tttgaggact tgtcagaaga agataagaac
    27001 ttgattcttt acggttcaga tggcaaggaa ttccatttcc actatgaaaa tgaatttggt
    27061 ggcgtgcgcg atatcgatat tccttttgag ggagttgtta ataatatcaa gcgtcgctat
    27121 catgaaacta atagtgacta cacccgcacc cagatgcgcc tttacatgaa tgagctgacc
    27181 tgcggaacct gtcacggcta tcgcctcaat gaccaggcct tgtctgtccg tgtgggtggc
    27241 gagaacgggc cacatatcgg agaaatttca gacctgtcta tcgcagacca cttggacttg
    27301 gtaagccagt tgactctatc tgaaaatgaa gccatcattg ctcgccctat tctcaaggaa
    27361 atcaaggacc gtttgacttt cctcaataac gtgggtctta actatctgac tctgtctcgt
    27421 tcagcaggaa ccctttcagg tggggaaagt cagcgcattc gtttggcaac ccagattggt
    27481 tccaacctat caggcgtcct ctatatccta gacgagccgt caatcggtct tcaccagagg
    27541 gacaatgacc gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa tactcttatc
    27601 gtggtggaac acgacgaaga taccatgcgt gaagctgatt atctgattga cgttggtcct
    27661 ggtgccggtg tttttggtgg tgagattgtt gcagcaggta cacctaagca agtggctcgc
    27721 aacagcaagt ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc agtaccagaa
    27781 gagcgccgtg tcggaaatgg tcgttttatt gaagtgatag gagcgcgtga gaacaacttg
    27841 caaaatgtca cggctcgctt tccactagga aaatttatcg cagtgacagg tgtgtcgggt
    27901 tcagggaaat cgactctaat caacagcatt ctcaaaaaag ccattgccca gaagctcaac
    27961 cgtaattcag acaaacctgg taagtttaag actattacag ggattgagca tgtcgaccgt
    28021 ttgattgata ttgaccagag ccctatcgga cggacgccga ggtctaaccc agctacctat
    28081 acaggagttt ttgacgatat acgtgacctt tttgctcaga caaatgaagc caagattcga
    28141 ggctacaaga aggggcgctt cagtttcaac gtcaagggag gtcgctgtga agcttgctca
    28201 ggtgacggga ttatcaagat tgagatgcac ttcttgccag atgtttatgt ggcttgtgaa
    28261 gtttgccacg gaacccgcta taacagtgaa accctagaag ttcactacaa ggaaaagaat
    28321 atttcgcagg tcttggatat gacggtcaac gatgcggtag aatttttcca acacattccg
    28381 aaaattcaac gcaaactcca gaccatcaag gatgtagggc taggctatgt gaccttggga
    28441 cagccagcta ccaccctttc tgggggagaa gcccaacgta tgaagttagc tagcgaactc
    28501 cacaaacgct cgacaggaaa atctttctac attctggatg agccgacgac agggcttcat
    28561 acagaggaca ttgctcgcct gctcaaggtt ttagctcgct ttgtagacga tggcaataca
    28621 gtcctcgtca tcgagcacaa tctggatgtt atcaagacgg cagaccatat cattgacttg
    28681 ggacctgagg gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc agaagaagta
    28741 gctgccaacg aagccagcta tacaggacac tatttgaaag gaaagttaca tcatgaataa
    28801 acgcgtacaa gcatttctag ctaaaatgca agaaaaagaa ctagatggtg tcatcatcaa
    28861 caatcttaaa aacgtctatt atttgactgg tttttggggc tcaaacggaa cagtctttat
    28921 cagccgtgac cgtcaggtct tagtgacaga ctctcgctat atcatcgcag ctaagcaaga
    28981 aaccagtggt tttgagattg tggctgatcg tgatgaattg gctgtcattg caggaattgt
    29041 taaggacatg ggcttgactc gtatcggttt tgaagatgag atttcagtgt cttattacca
    29101 ccgtatgcag gcagcttttg caggtttgga cttgcttcca caaactcagt ttgtggaagg
    29161 tcttcgtatg attaaggatg aggcagagat tgcagcgatt cgcaaggctt gttctatctc
    29221 agaccaagct ttccgcgatg cgcttgactt tatcaaacca ggaaaaactg aaattgagat
    29281 tgccaacttc cttgatttcc gcatgcgtga gttgggagca tctggcttat cttttgatac
    29341 gatcctagct agcggtatca attcttctaa accccatgcc catccaatgc acaaaccagt
    29401 ggagttggga gaagccatta ccatggactt cggctgtctc tatgaccact atgtcagtga
    29461 tatgacccgg actatctatc tagggcatgt tagcgatgag caggcagaga tttacaatac
    29521 ggttctaaaa gctaaccaag ccttgattga ccaagctaag gcaggcttag gtttccgtga
    29581 ctttgacaaa atccctcgtg atattatcat tgaggcaggt tatggtgact actttactca
    29641 cggcattggc cacggtattg gtctggatat ccatgaggaa ccctacttta gccagacttc
    29701 tacagaaact attaagacag gtatggcctt gaccgatgaa ccaggtatct atatcgaagg
    29761 caaatatggc gttcgtatcg aggatgatat cctgattaca gagacaggtt gtgaattatt
    29821 gaccctagct ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa aagtacgaaa
    29881 atgacgaaaa aagtcaaaaa aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta
    29941 taatagacta aactgatagt aacatgtagc gaaaggggta ggtacatgat taaaatttat
    30001 acagtctcaa gttgtactag ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta
    30061 agttataaag aacaaaacct tggtaaagaa ggaattacga gagaagaatt actggatatt
    30121 ctaaccaaaa cagataacgg aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa
    30181 gcccttggag tggatattga agatttgagt gtcaatgaag ttctcaatct gattatggaa
    30241 acaccgagaa ttttaaagag cccaatcctt gtagatgaaa aacgcctgca agttggctac
    30301 aaggaagacg atattcgtgc cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa
    30361 gcacgtttgc gtgcagctct ataaacatca aggctgggag cacttcccag tcttattcta
    30421 ttttaatttc aaaaagaaag aagaaagaaa tgaaaaaaat agttcttgtt agtctagctt
    30481 tcctttttgt cctggttggt tgcggacaga aaaaagaaac tggaccagct acaaaaacag
    30541 aaaaagatac gcttcagtcg gcattgccag ttattgaaaa tgctgagaag aatacagttg
    30601 taactaagac tttggtcttg cccaagtcag atgatggtag ccagcagaca caaacaatta
    30661 cttacaaaga caagactttt ttgagtctaa ctatccaaca aaaacgtcca gtctctgatg
    30721 agttgaagac ttatattgac caacatggag tggaagaaac tcaaaaagct cttcttgaag
    30781 cggaggagaa ggataagtct atcattgaag ctcgtaaatt ggcaggtttc aaacttgaaa
    30841 caaaactatt gagcgcaacg gaacttcaaa caacgactag ttttgatttt caagttctgg
    30901 atgtcaagaa ggcttcccag ttggaacatc tgaagaatat tggtttggaa aatcttttga
    30961 aaaatgaacc aagcaaatat atttcagata gattggcaaa tggcgcgaca gaacaataga
    31021 aaatccaaat aaatagactg cctgaattgt agaaggtaag gaattatgct ataatggtac
    31081 tattctaagg aaagagggtg ttagaatggg atttactgaa gaaacagtac gttttaaatt
    31141 ggacgattcc aataaaaaag aaattagcga aactttgaca gatgtttatg cttcgttgaa
    31201 cgataagggt tacaacccaa ttaaccaaat cgtaggttac gtattgagtg gagaccctgc
    31261 ctacgttcct cgttataata atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat
    31321 cgttgaggaa ttggttcgct actacctaaa aggacaagga gtcgatctat aacctatgag
    31381 aattatggga ttggacgtcg gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg
    31441 ttttacagct caagggcttg aaatcatcca gataaatgaa gaacaaggcc aatttggttt
    31501 tgaccgcgtt aaggaattgg ttgatactta caaggtggaa cgatttgtag tgggcttgcc
    31561 taaaaacatg aacaatacaa gtggaccgcg cgtagaagct agtcaagcct acggagcaaa
    31621 gctagaagag ttttttggtt taccagtaga ctatcaggat gaacgcttga caacagtggc
    31681 tgctgagcgc atgttgattg aacaagcaga tatcagtcgc aataagcgca agaaagtcat
    31741 tgataagtta gcagctcagc tgattttaca aaattattta gatagaaaat tttaatataa
    31801 aggagaggct atgtcacacg atcataacca cgaccacgaa gaacgtgaac taatcacact
    31861 agtagatgag caaggaaatg aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga
    31921 agaatttggt aaaaactatg ttcttctagt accagttaac gcagaagaag acgaagacgg
    31981 acaagttgaa atccaagctt actcattcat tgaaaatgaa gatggaacag aaggcgaatt
    32041 gcaaccaatc ccagaagact cagaagacga atggaacatg attgaagaag tcttcaacag
    32101 ctttatggag gagtaaaaac gtccggggga cgtttttagc cctgcgctag aaattagaaa
    32161 cgcaggtagt ctgggagact gtatcagccc aactccagaa atggggaaga gttggaacat
    32221 ctagtggatg tttttagccc atattcacat tcatagtagc tagttattag ctaaccaggt
    32281 aagaggtcgg gacgaaaatc ctggccttgt ttttattagt aaccatactt taatgcgata
    32341 attgattgga cttttgtcaa ggagatgtgt atgtttgaag tagaagaatg gctccatagt
    32401 cggattggtt tgaattttcg atcaggtttg ggccgaatgc agcaagcggt ggatttgtta
    32461 ggaaatcctg agcagtctta ccctattatc cacgtaacag ggactaatgg gaaaggatct
    32521 accattgctt ttatgaggga attatttatg gggcatggca aaaaagttgc gacctttacc
    32581 tcccctcata tcgtctctat caatgaccga atctgcatta atgggcaacc tatagcagac
    32641 gcagacttta tccgtttgac tgatcaggtc aaggagatgg agaaaacgct tctgcaaact
    32701 cctgcccagt tgtccttttt tgaattgctg accttagttg cttttcttta ttttagggag
    32761 caagaggtgg atttggtttt attagaagtg ggaattggtg gcttacttga cacgaccaat
    32821 gtggtaactg gagatcttgc tgtcatcacc tccattgggc ttgaccatca agaaaccttg
    32881 ggtgatagtc tagaagcaat tgcagagcag aaagctggta ttttcaaggc tggtaagaag
    32941 gcagtgattg cgaaattgcc tccagaagct aggcttgtct gtcagaaaaa agccgaatct
    33001 ttagctgtta acctttatca ggcaggtcaa gattttttaa tgctgaatgg tgatttttca
    33061 agctctttac taaatctttc acagctgaac ataggcttag aaggagtcta tcagcaggag
    33121 aatgcagcct tggcgttgca aacttttctt ctttttatgg gagaaggaaa ggaagctgtt
    33181 gatgaacagg ctgtaagaaa ggccttggaa cagacccatt gggctggtcg cttggagcgt
    33241 attcgcccac agatttactt ggatggtgct cataacctcc ctgccttgac tcgcttggtt
    33301 gagtttatca aagaaaaaga gcaggaaggc tatcgacctc aaatcctttt tggagccttg
    33361 aaacggaagg attatcaagg gatgttaggt tacctgactg aaaaattgcc tcaggtggaa
    33421 ctcaaggtga ccggctttga ctatcagggg gctttggacg aaagggatgt gacaggttac
    33481 gatatagttt cttcttaccg agaatttatc agcgattttg aagaaagagc agatgctcag
    33541 gatttgctgt tcgttacagg gtctctctat tttatctcag aagtacgggg ctacctgctg
    33601 gaccgtgagc agataaattg acccccttgt ttgaacttgt tatactaggg gaattgctgg
    33661 ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat
    33721 tcacactttc tcttgcttct ctagcaagtt ttagtctctt agtagcttgt tcacaaagag
    33781 ctcaacaggt tcaacagcct gttgctcagc agcaggtcca acagcctgct caacagaata
    33841 ccaatactgc aaatgcagga ggtaaccaaa atcaagcggc tccagtacaa aaccaacctg
    33901 ttgctcaacc gaccgatatt gatgggactt atactggtca ggatgacgga gaccgtatca
    33961 ctttagtggt aactggaacg actggtacat ggactgagct cgaatctgac ggggatcaga
    34021 aagtcaaaca ggttacattt gattcagcaa atcaacgcat gattattggc gatgatgtca
    34081 aaatttacac tgtaaacggt aatcaaatcg tcgtagatga tatggataga gacccatcgg
    34141 accaaatcgt tttaactaaa taagactatg caagtagaaa gggctggatt tttcagcctt
    34201 tttactttta cctagaaaat aatcataaat acttgccttc taccgaatac ctgcgttata
    34261 ctagtatcaa ttacttgttt ttagcattca aactatcaag gaggggatat gaaatatagg
    34321 aaatttcaat tattgatgtc caagtatggc tttagtcttt cgattatgct acttgaactt
    34381 tgtcttgttt ttggtctctt tctttattta ggacgcatgg ctcccatttt atggattact
    34441 gtcctcattc tactgagtat catcacaatc atttcgatag tcaaccgtaa tacgactcct
    34501 gagaataagg taacctggtt gttagtagcc tttgtgccag tatttggtcc cttgctctat
    34561 ctgatgtttg gtgaaaggcg attgtccaaa aaagaaatca aacaactgaa gaagctaggc
    34621 tctatgcatt tccaagaagc aaatagccag ctactaaaag agaaattaaa agaaagtgac
    34681 aaggcagctt atggagtcat caagtcctta ttgagtatgg ataccaatgc tgacatctat
    34741 gatcaaactg cctctacatt ttttcctaac ggagaagcta tgtggaaaaa gatggtagaa
    34801 gatcttaaaa aggctgagaa atttattttc ttggaatatt acattataga agaaggtttg
    34861 atgtggaatc gcatactaga tatactagag caaaaggtag ctcagggtgt agaggttaag
    34921 atgctctatg atgatatcgg ctgtatggct actttaacag gagattatgc acatcgactt
    34981 cgtcagctgg gcatcgaggc ccataaattc aataaagtta ttcctcgttt gacagtggct
    35041 tataataaca gagatcatag aaaaatattg attgttgatg gtcagatagc ctatactggt
    35101 ggggtcaatc tggcagatga gtacattaac cacgtcgaga gatttggtta ttggaaggat
    35161 agtggaattc gcttagacgg actagcagta aaagctctga cacgcttatt tttgaccact
    35221 tggtacatta atcgaggaga aattagtgat tttgatcaat atcatttaga aaatcattct
    35281 atcccgagtg acggtttaac cattccatac ggaagtggac ccaagccaat ttttcgagcg
    35341 caggtaggga aaaaagttta tcagagttta atcaatcaag caacagaatc ggtctatatt
    35401 acgacacctt atttgattat agattatgat ttaacagaga caatcaaaaa tgcagctatg
    35461 agaggggtcg atgttcgaat tatcacccct tacataccag ataagaagtt cattcagtta
    35521 gtcacgagag gagcttatcc cgaccttctt tctgctggtg ttcggattta tgagtatagt
    35581 ccaggtttta ttcatagtaa gcagatgttg gtagacgaag attttgcggt ggtggggaca
    35641 atcaatctcg actaccggag cttggtacac cattatgaaa atgcagtctt actctataaa
    35701 actccttcta taagggaaat cgcccgagat tttcgaaata tatttgcaga ttctcaggaa
    35761 gtctatcctc attctatcaa aacgagctgg tatcaaaagc ttgtaaaaga aatcgcccag
    35821 ctattcgccc ctatcttata agaaatctag aacttaggat acaaaccaga cctatttttc
    35881 ttgtctttta cgaatagaaa gaaagaggag gggaattcat gctaactaag gaagaagtga
    35941 atgatatgat tgagttcaaa cagacacatt tacaccgctt tcgggaaatt gaaacctttg
    36001 tgaaactatg caaaaaatca ctcaaacagc catcgcaagc tgacaatcct aggacttttt
    36061 gatatactaa gacagataaa ttgaacagga gaaacgatat gagtgtgtat ggtagagtag
    36121 aagaagttca taaggagaat cgtgaacctc tagaatacca aatcgaacaa gaatcgcatc
    36181 atcgtgaatc aagtcgtctt cctttggtga aaattttact atggagtacg cttgtaacgg
    36241 ggataactct aggagtgccg ctattactcg acttaatgag tgcacaagaa gtgcaggatt
    36301 tttatgcagg ttgggcgctt catcagacag ggaagattta cagcgactat tatggaagtc
    36361 aaggtttgct ttattatttg ctgacttacg tgagtcaggg cggatttttc tttgccatct
    36421 ttgagtggtt agccttggta gcaggcggat ttttcctttt tagatcagcg gacaccttga
    36481 cagagcaagg agaccaagct ggacatctgg tgactatttt ttacatgcta gttacaggtc
    36541 ttgcttttgg tggaggctat gcgactcttt tagcgcttcc tttcttattc gcagccttta
    36601 gtttagttgc ggcttaccta agcaatccaa gccatgataa gggatttgta cggattgggc
    36661 tagctttggc aggcggattt ttctttgctc ccttatcatc gctcctgttt attgctgtag
    36721 tgagtttagg cttgttggtc tttaaccttg ggcatagacg ttttgtgcat gggttttatc
    36781 agtttcttgc agtggcttta ggtttttcac ttgtctttta tccaactgcc tactatagtg
    36841 ctgcaacagg aagttttggg gatgcgatta gtggtattcg ttatcctatt gacagtattc
    36901 gctttgattt tacttctaaa attttagaga atatgttttt ttatggcttg ttgtcccttg
    36961 gtttgggatt tgtggtttgt atctttttag gtctctttca atccaaaccc tttaaactat
    37021 acgtcatttc ggttcctgca agtcttgtgg taattttagg tttgatttta cttttctttt
    37081 cacaagagcc tctgcacgct tcttatttga tggtcgtctt ccctgttttc ctacttttat
    37141 tggtaaccaa tattaagagt caacagaggg ggcgtagtgc tagaagaagc cgaagagaaa
    37201 cgccagttag cctatggagt cgtttcttca aaggaaatct atatctgcta gtttttgggt
    37261 ttgtctatct tttgtctgtt ccttttttga tgaagtttgt cctttatcca gtaccttatc
    37321 aagaacgtaa tcgtcttgct gatttggtaa aagaggagac aaatacggaa gatgctatct
    37381 atgcatggga tgatactgcg actctttatc gtaagagtga gcgcttgtcg ccatcggcga
    37441 ttttgtcccc gttgcactat acagcaactg aggaaaatcg taataagtta cttaatgact
    37501 tgaaagaaaa acaacctaag gtgattgtgg taaatgacaa ggtggtagtc tggtctgaag
    37561 tggaaacact cttaaaagaa aattaccaac aagtaaagac tgattactca gagtttaaag
    37621 tctataaaat taaataacca aatcaatatc ttgtgtattt ttaaaaattt taggattttt
    37681 aacacaagat attgattttt ctttttagag tggtataata ctttttagaa agaacatttt
    37741 agaaaagagc atgcgtatga ttgcactaga agaaaaaatt acaattttgc caactctctt
    37801 cgtcgagaaa cgagatggga gacgtgttgt atttgatgtg gacaagattg acaaggctct
    37861 ccgcaaggcg gctgacaagg ttatggatgt gacacccctg gttgaaaaac gcctcaatga
    37921 tctgactgag cgaattatta cagaaattca tagtcgcttt ccacagggaa ttaagattta
    37981 cgaaattcaa aatatcgtag aacatgaact ccttgaagcc aaagaatatg cactggctga
    38041 ggagtatatt acttatcgga cacagaggga ttttgagcgc tcaaaagcga cggatatcaa
    38101 ctttagtatt cataaacttc tcaacaaaga ccagacagtt gtcaatgaaa atgctaataa
    38161 agacagtgat gtctttaaca ctcagcgtga tttgacagca gggattgttg ggaaatcaat
    38221 cggactgcaa atgcttccta agcacgtagc caatgcccac caaaaggggg atatccacta
    38281 tcacgatttg gactacagtc cctatacccc tatgaccaac tgctgtttga ttgattttaa
    38341 gggtatgttg gaaaatggtt ttaagattgg aaatgcagag gtagagagtc ccaagtctat
    38401 ccagactgcg acagcacaga tttctcaaat cattgccaac gttgcttcta gccagtacgg
    38461 tggctgttca gctgaccgta tcgatgaaat tttggcgcct tatgcagaga agaattatca
    38521 aaaacatctc aaagatgcag aagagtgggt attgcctgaa aaacgggaag attacgcttg
    38581 gaagaaagcg caaaaggaca tctacgatgc catgcaatct cttgagtatg aaatcaatac
    38641 tctcttcact tcaaatggac aaacaccttt tacttcgtta ggttttggtc tgggaaccag
    38701 tcgttttgaa cgagaaattc aaaaagctat tttaaacatt cgcatcaagg gtcttggttc
    38761 agaacaccgt acggctatct ttcctaaact tatctttacg cttaaaagag gcctcaactt
    38821 agaggaagga actcccaact atgacatcaa gcagttggct ctagagtgtg caaccaagcg
    38881 gatgtatcca gacgtcttgt cttatgataa gattgttgat ttgacaggtt ctttcaaagt
    38941 tcctatgggc tgccgttctt tccttcaagg gtggaaggat gaaaatggtg tagaagtcaa
    39001 ttcaggtcgc atgaatctgg gtgttgtgac ggttaatctg cctcgtattg ctcttgagtc
    39061 tgaaggtgat atgaataagt tctgggaaat cttcaacgag cgaatgaata tcgcagaaga
    39121 tgctcttgtt taccgtgtcg aacgcactaa agaggcgaca ccagcgaatg ctcctattct
    39181 ttatcagtac ggtgcttttg gccatcgtct aggtaaagaa gaaagtgttg accagctctt
    39241 taagaatcgt cgtgcgaccg tttcgctggg ctatatcggc ttgtatgaag tagcgacagt
    39301 tttctttggt aacagctggg aaagtaatcc agatgctaag gaattcacgc tagacatcat
    39361 tcacgatatg aaacgccgtg tagaagagtg gtcagaccaa tatggctacc atttctctat
    39421 ctactcaaca ccatccgaaa gtctgacaga ccgtttctgc cgactagata tagacaagtt
    39481 tggctctatt cctgatatca cagacaagga atactacacc aactctttcc actacgatgt
    39541 tcgtaaaaat ccaacaccgt ttgaaaaatt ggactttgag aaagtctatc cagaagcagg
    39601 tgcgtcaggt ggtttcatcc attattgtga gtatccagtc cttcagcaaa atccaaaggc
    39661 cttggaagct gtctgggatt atgcttatga ccgtgtaggc tatctaggca ccaatactcc
    39721 gattgaccgt tgctacaagt gtgactttga aggggatttt gaaccaactg agagagggtt
    39781 tgcttgtcca aactgtggca atagcgaccc taaaacagta gatgtggtga agcgaacttg
    39841 tggctaccta ggtaatcctc aagcaagacc gatggtcaac gggcgtcaca aggaaatcgc
    39901 tgcgcgtgtc aaacatatga atggttcaac gattaaaata gctgggcatc aagtaacaaa
    39961 ttagaaagaa atgaaatggg aaaatatcaa ctagacgata aggggcgcgc acaagtgacc
    40021 cgttatcacg agaaacactc taaaggtgga gctggtaaga aagaacgctt gcttagcttc
    40081 agagaacaat ttttaaacaa gaacaagaaa aaataaaagt gagagccagc tctcgctttt
    40141 ctcatagtgg gaggtaagga tggaattacg cagaccaaga ttagcggata agaaagctgt
    40201 tttagatatg atgacagagt ttgaaaaatt tcagtcgcct cacgacggcg gtttctggga
    40261 tacagagaac tttgtgtatg aagactggtt agaaagcaat caggaacagg aaatggggat
    40321 taatctgcct gaaggatggg ttcctgcaat tcagttagtg gctttttctg agaaaggtca
    40381 agcagttgga tttcttaatc tccggttgcg cctcagtaac tttctactag aagaaggtgg
    40441 ccacattggc tactccattc gtccatctga aagaggcaag ggttatgcaa aagagactct
    40501 ccgtcagggc ttgcaagttg ctaaggaaaa gaacatcaag aaagctctgg tgacctgtag
    40561 cgtgaataat cctgctagca gagcagtcat tctagcaaat ggtggaatat ttgaggatgc
    40621 tcgcaatgga gtcgagcgtt attggataga ggtagcgaat gaataatcca aaaccacaag
    40681 aatggaaaag cgaggaactt agtcaaggtc gtatcattga ctacaaggcc tttaactttg
    40741 tggacggcga aggcgtgcgt aactctctct atgtatcagg ctgtatgttt cactgcgagg
    40801 gatgttataa tgttgcgact tggtctttta atgctggcat tccctataca gcagaattag
    40861 aagagcagat catggcagat cttgctcagc cctatgttca aggtttgact ttgttgggag
    40921 gggagccttt tcttaatact gggattctct tgccacttgt taagcggatt cggaaggaat
    40981 tgccagacaa ggacatctgg tcctggaccg gctacacttg ggaagaaatg atgttggaaa
    41041 ctccagataa actggaattc ttgtcactga ttgacattct tgtcgatgga agatatgatc
    41101 gaactaagag aaatcttatg ctccagtttc gaggttcatc taaccaacga attatcgatg
    41161 tgcaaaaatc gctcaaaagt gggcaagtag tgatttggga caagctcaat gacggaaaag
    41221 aaagctatga acaggtgaag agagaatgaa gaaaaaagac ttagtagacc aactagtctc
    41281 agagatcgag acggggaaag tcaggacact gggaatatac ggtcatggag cttcaggtaa
    41341 atcaaccttt gcacaggaat tgtaccaagc tttagattct actacagtaa atttgctaga
    41401 aacagatccc tatatcacct ccggacgcta tttggtagta cccaaggacg cgccgaatca
    41461 aaaggtgaca gccagtctgc cagtggcgca tgaactggag agtttgcaga gagatatcct
    41521 tgccttgcag gcgggtatgg atgtcttgac aattgaagaa ccttggaagg ctagtgaggt
    41581 cttgtctgga gccaaaccaa ttttgattgt cgaagggatg tctgttggtt ttctacccaa
    41641 ggaactcttt gaaaaaacca tctgtttcta cacggatgag gagaccgaat taaagcgacg
    41701 ccttgctaga gatacgactg tgagaaatcg cgatgcatcc tttatattgg ctagccatca
    41761 gatgagacgg gagcagtatc tgcgatacta taaagaaact gagtctaagg cggatatctt
    41821 agtggaccaa tcagaagata aatttgatgt caagaggact taacttatgt atagaagaaa
    41881 tatagaagaa aatccctaat tttagaaaga aaaagtagga aaacagtttc atcccaaaaa
    41941 aacgaaaaaa cctaacaaat cccttgcaat cgcaggggat ttgtgttatt ctattatggt
    42001 gctgtaaatt acagccttag ttttgatgca agaggttgcg acacgctcgg ttgcattgcc
    42061 acgcaacacc gcgtcggttt tcttgtggag ctagcctatt atcttaaata gacgaaaagg
    42121 agaaaaagat ggcaaacaaa aaaatccgta tccgtttgaa agcttacgaa caccgtacgc
    42181 ttgacacagc ggctgcaaaa atcgtagaat cagctactcg tacaggtgca caagttgcgg
    42241 gtccaatccc acttccaact gaacgtagcc tctacacaat cattcgtgcg actcacaaat
    42301 acaaagactc tcgcgaacaa tttgaaatgc gtacacacaa acgtttgatc gatatcgtta
    42361 acccaactca aaaaacagtt gatgccttga tgaaattgga tcttccaagt ggtgtaaacg
    42421 tagaaatcaa actttaatct aaaatataaa agagcagagg ctggtgtttc aatctaattg
    42481 aacacgggct aaactcggtg tgaaaaagat aaacttcctc gcgtctgcta gacactgtgt
    42541 cagtttccta ttttcacttt gagtttgacg ccctttgtat cttagacttg agcataaaaa
    42601 acgctcgtta aaaacttttt gaataaaaaa tatagaaaag gaactatttt ctcatgacaa
    42661 aaggaatctt agggaaaaaa gtgggaatga ctcaaatctt cactgaagct ggcgaattga
    42721 tccctgtaac agttattgaa gcaactccaa acgttgttct tcaagttaaa actgttgaaa
    42781 cagacggata caacgctatc caagttggtt tcgatgacaa acgcgaagta ttgagcaaca
    42841 aacctgctaa aggacatgta gcgaaagcta acacggctcc taagcgcttc attcgtgaat
    42901 tcaaaaacgt tgaaggcttg gaagttggtg ctgaaattac agttgaaaca ttcgcagctg
    42961 gagacgttgt tgacgtaact ggtacttcta aaggtaaagg tttccaaggt gttatcaaac
    43021 gccacggaca atcacgtgga ccaatggctc acggttctcg ttaccaccgt cgtccaggtt
    43081 ctatgggacc tgttgcacct aaccgcgtat tcaaaggtaa aaaccttgca gggcgtatgg
    43141 gtggcgaccg cgtaacaatt caaaaccttg aagttgtaca agttgttcca gaaaagaacg
    43201 ttatccttat caaaggtaac gtaccaggtg ctaagaaatc tcttatcact atcaaatcag
    43261 cagttaaagc tggtaaataa taaagaaagg ggaaatcagt cacaatggca aacgtaacat
    43321 tatttgacca aactggtaaa gaagctggcc aagttgttct tagcgatgca gtatttggta
    43381 tcgaaccaaa tgaatcagtt gtgtttgatg taatcatcag ccaacgcgca agccttcgtc
    43441 aaggaacaca cgctgttaaa aaccgctctg cagtatcagg tggtggacgc aaaccatggc
    43501 gtcaaaaagg aactggacgt gctcgtcaag gttctatccg ctcaccacaa tggcgtggtg
    43561 gtggtgttgt cttcggacca actccacgtt catacggcta caaacttcca caaaaagttc
    43621 gtcgcctagc tcttaaatca gtttactctg aaaaagttgc tgaaaacaaa ttcgtagctg
    43681 tagacgctct ttcatttaca gctccaaaaa ctgctgaatt tgcaaaagtt cttgcagcat
    43741 tgagcatcga ttctaaagtt cttgttatcc ttgaagaagg aaatgaattc gcagctcttt
    43801 cagctcgtaa ccttccaaac gtgaaagttg caactgctac aactgcaagt gttcttgaca
    43861 tcgcaaatag cgacaaactt cttgtcacac aagcagctat ctctaaaatc gaggaggttc
    43921 ttgcataatg aatttgtatg atgttatcaa aaaacctgtc atcactgaaa gctcaatggc
    43981 tcaacttgaa gcagggaaat atgtatttga agttgacact cgtgcacaca aacttttgat
    44041 caagcaagct gttgaagctg ctttcgaagg tgttaaagtt gccaatgtta acacaatcaa
    44101 cgtaaaacca aaagctaaac gtgttggacg ttacactggt tttactaaca aaactaaaaa
    44161 agctatcatc acacttacag ctgattctaa agcaatcgag ttgtttgctg ctgaagctga
    44221 ataatctaag gaggaaatat cgtgggaatt cgtgtttata aaccaacaac aaacggtcgc
    44281 cgtaatatga cttctttgga tttcgctgaa atcacaacaa gcactcctga aaaatcattg
    44341 cttgttgcat tgaagagcaa ggctggtcgt aacaacaacg gtcgtatcac agttcgtcac
    44401 caaggtggtg gacacaaacg tttctaccgt ttggttgact tcaaacgtaa taaagacaac
    44461 gttgaagcag ttgttaaaac aatcgagtac gatccaaacc gttctgcaaa catcgctctt
    44521 gtacactaca ctgacggtgt gaaagcatac atcatcgctc caaaaggtct tgaagtaggt
    44581 caacgtatcg tttcaggtcc agaagcagat atcaaagtcg gaaacgctct tccacttgct
    44641 aacatcccag ttggtacttt gattcacaac atcgagttga aaccaggtcg tggtggtgaa
    44701 ttggtacgtg ctgctggtgc atctgctcaa gtattgggtt ctgaaggtaa atatgttctt
    44761 gttcgtcttc aatcaggtga agttcgtatg attcttggaa cttgccgtgc tacagttggt
    44821 gttgtcggaa acgaacaaca tggacttgta aaccttggta aagcaggacg tagccgttgg
    44881 aaaggtatcc gcccaacagt tcgtggttct gtaatgaacc ctaacgatca cccacacggt
    44941 ggtggtgaag gtaaagcacc agttggtcgt aaagcaccat ctactccatg gggcaaacct
    45001 gctcttggtc ttaaaactcg taacaagaaa gcgaaatctg acaaacttat cgttcgtcgt
    45061 cgcaacgaga aataatatta aactagtcgc ttaagcaact agtaaatccg ccagctcggt
    45121 agcgctccat aggagtgcaa gccgctgtgg tacaacattt aaaggagaaa atataaaaat
    45181 gggacgcagt cttaaaaaag gacctttcgt cgatgagcat ttgatgaaaa aagttgaagc
    45241 tcaagctaac gacgaaaaga aaaaagttat taaaacttgg tcacgtcgtt caacgatctt
    45301 cccaagtttc attggttaca ctattgcagt ttatgacgga cgtaaacacg tacctgttta
    45361 catccaagaa gacatggtag gccacaaact tggtgaattt gcaccaactc gtacttacaa
    45421 aggtcacgct gcagacgaca agaaaacacg tagaaaataa ggagaacata aatggcagaa
    45481 attacttcag ctaaagcaat ggctcgtaca gtacgtgttt cacctcgtaa atcacgtctt
    45541 gttcttgata acatccgtgg taaaagcgta gccgatgcaa tcgcaatctt gacattcact
    45601 ccaaacaaag ctgctgaaat catcttgaaa gttttgaact cagctgtagc taacgctgaa
    45661 aacaactttg gtttggataa agctaacttg gtagtatctg aagcattcgc aaacgaagga
    45721 ccaactatga aacgtttccg tccacgtgcg aaaggttcag cttcaccaat caacaaacgt
    45781 acagctcaca tcactgtagc tgttgcagaa aaataaggag gtaaaatcgt gggtcaaaaa
    45841 gtacatccaa ttggtatgcg tgtcggcatc atccgtgatt gggatgccaa atggtatgct
    45901 gaaaaagaat acgcggatta ccttcatgaa gatcttgcaa tccgtaaatt cgttcaaaaa
    45961 gaacttgctg acgcagcagt ttcaactatt gaaatcgaac gcgcagtaaa caaagttaac
    46021 gtttcacttc acactgctaa accaggtatg gttatcggta aaggtggtgc taacgttgat
    46081 gcactccgtg caaaacttaa caaattgact ggaaaacaag tacacatcaa catcatcgaa
    46141 atcaaacaac ctgatttgga tgctcacctt gtaggtgaag gaattgctcg tcaattggag
    46201 caacgtgttg ctttccgtcg tgcacaaaaa caagcaatcc aacgtgcaat gcgtgctgga
    46261 gctaaaggaa tcaaaactca agtatcaggt cgtttgaacg gtgcagatat cgcccgtgct
    46321 gaaggatact ctgaaggaac tgttccgctt cacacacttc gtgcagatat cgattacgct
    46381 tgggaagaag cagatactac atacggtaaa cttggtgtta aagtatggat ctaccgtggt
    46441 gaagttcttc cagctcgtaa aaacactaaa ggaggtaaat aaccaatgtt agtacctaaa
    46501 cgtgttaaac accgtcgtga gttccgtgga aaaatgcgcg gtgaagcaaa aggtggaaaa
    46561 gaagtagcat tcggtgaata cggtcttcaa gctacaacta gccactggat cactaaccgc
    46621 caaatcgaag ctgctcgtat cgccatgact cgttacatga aacgtggtgg taaagtttgg
    46681 attaaaatct tcccacacaa atcatacact gctaaagcta tcggtgtgcg tatgggatct
    46741 ggtaaagggg cacctgaagg ttgggtagca ccagttaaac gtggtaaagt gatgttcgaa
    46801 atcgctggtg tatctgaaga gattgcacgt gaagcgcttc gacttgctag ccacaaattg
    46861 ccagttaaat gtaaattcgt aaaacgtgaa gcagaataag gagaaggcat gaaacttaat
    46921 gaagtaaaag aatttgttaa agaacttcgt ggtctttctc aagaagaact cgcgaagcgc
    46981 gaaaacgaat tgaaaaaaga attgtttgaa cttcgtttcc aagctgctac tggtcaattg
    47041 gaacaaacag ctcgcttgaa agaagttaaa aaacaaatcg ctcgtatcaa aacagttcaa
    47101 tctgaagcga aataatagac tagggaagga gaaatttcaa tggaacgcaa taatcgtaaa
    47161 gttcttgttg gacgtgttgt atctgacaaa atggacaaga caatcacagt tgtagttgaa
    47221 acaaaacgta accacccagt ctatggtaaa cgtattaact actctaaaaa atacaaagct
    47281 catgatgaaa acaatgttgc caaagaaggc gatatcgtac gtatcatgga aactcgcccg
    47341 ctttcagcta caaaacgttt ccgtcttgta gaagttgttg aagaagcggt catcatctaa
    47401 tcaaacctga aaggagaaaa ctgaaatgat tcaaacagaa actcgtttga aagtcgcaga
    47461 caacagcggt gctcgcgaaa tcttgactat caaagttctt ggtggttcag gacgtaaatt
    47521 tgcaaacatc ggtgatgtta tcgtggcatc tgtaaaacaa gctactcctg gtggtgcggt
    47581 taaaaaaggt gacgttgtta aagcagttat cgttcgtact aaatcaggtg ctcgtcgtgc
    47641 tgatggttca tacatcaaat ttgacgaaaa cgcagcagtt atcatccgtg aagacaaaac
    47701 tcctcgcgga acacgtatct ttggcccagt tgcacgtgaa ttgcgtgaag gtggcttcat
    47761 gaagatcgtg tcacttgctc cagaagtact ttaattttta ggaacaaact agtcccctag
    47821 cttcaagcta gggtgccctt atgggcgtaa gaaaaatcaa ggagaaacct aatgtttgta
    47881 aaaaaaggcg acaaagttcg cgtaatcgct ggtaaagata agggaacaga agctgttgtc
    47941 cttactgccc ttccaaaagt aaacaaagtt atcgttgaag gtgttaacat tgttaagaaa
    48001 caccaacgtc caactaacga gcttcctcaa ggtggtatca tcgagaaaga agcagctatc
    48061 cacgtatcaa acgttcaagt tttggacaaa aatggtgtag ctggtcgtgt tggttacaaa
    48121 tttgtagacg gtaaaaaagt tcgctacaac aaaaaatcag gcgaagtgct tgattaatca
    48181 cgaaggaaag gagaagtata atggcaaatc gtttaaaaga aaaatatctt aatgaagtag
    48241 ttcctgcttt gacagaacaa ttcaactact catcagtgat ggctgtgcct aaagtagata
    48301 agattgtttt gaacatgggt gttggtgaag ctgtatcaaa cgctaaaagc cttgaaaaag
    48361 ctgctgaaga attggcactt atctcaggtc aaaaaccact tatcactaaa gctaaaaaat
    48421 caatcgccgg cttccgtctt cgtgaaggtg ttgcgatcgg tgcaaaagtt acccttcgtg
    48481 gtgaacgtat gtacgaattc ttggataaat tggtatcagt ttcacttcca cgtgtacgtg
    48541 acttccacgg tgtcccaaca aaatcatttg atggacgcgg gaactacaca cttggtgtga
    48601 aagaacaatt aatcttccca gaaatcaact tcgatgacgt tgacaaaact cgtggtcttg
    48661 acatcgttat cgtaacaact gctaacactg acgaagagtc acgtgcattg cttacaggcc
    48721 ttggaatgcc ttttgcaaaa taatatagga ggtaaatcta atggctaaaa aatcaatggt
    48781 agctagagag gctaaacgcc aaaaaattgt tgaccgttat gctgaaaaac gtgctgcatt
    48841 aaaggcggca ggggactacg aaggtttatc taaattacct cgcaacgcct caccgactcg
    48901 tttacataat cgttgtagag ttacggggcg cccacattca gtttaccgca aatttggtct
    48961 gagtcgtatc gcttttcgcg aacttgcgca taaaggtcaa attcctggtg taacaaaagc
    49021 atcttggtaa tttaagatat caagggtgtc aaaactccaa gtaaaaatag gaaacttgac
    49081 gaagaaacta aagtttctag gaaagtttat ctttttcaca cagagtttag cccgggttca
    49141 attgggcttg ccaatttgaa cccgagctac agctttggca aaaaagacca atttgctttg
    49201 gagcattgct tctgcattaa attgtctatt tttgctcgtg ctgttacgct ctttgtatca
    49261 tgtattaact agcaagtgca acttgcaaac tactagtaag aggagaaaaa caaaatggtt
    49321 atgactgacc caatcgcaga cttcctaact cgtattcgta atgctaacca agctaaacac
    49381 gaagtacttg aagtacctgc atcaaacatc aaaaaaggga ttgctgaaat ccttaaacgc
    49441 gaaggttttg taaaaaacgt tgaaatcatc gaagatgaca aacaaggcgt catccgtgta
    49501 tttcttaaat acggaccaaa tggtgagaaa gttatcacta acttgaaacg tgtttctaaa
    49561 ccaggacttc gtgtctacaa aaaacgtgaa gaccttccaa aagttcttaa cggacttgga
    49621 attgccatcc tttcaacttc tgaaggtttg cttactgata aagaagcacg ccaaaagaat
    49681 gttggtggtg aggttatcgc ttacgtttgg taaaatcaag atacaaagct cgtaaagaac
    49741 aaagcaaaat taggaagttg gagaagtttg tttacaaaca agccaactta tctattttgc
    49801 acagttctta gagcgtgttc agttcagctc ttgaactaaa taagtatctg aaccccgtga
    49861 aaactggccg ttttggcctg acaatttaac aggagaaaat aaacatgtca cgtattggta
    49921 ataaagttat cgtgttgcct gctggtgttg aactcgctaa caatgacaac gttgtaactg
    49981 taaaaggacc taaaggagaa cttactcgtg agttctcaaa agatattgaa atccgtgtgg
    50041 aaggtactga agtaactctt caccgtccaa acgattcaaa agaaatgaaa actatccacg
    50101 gaactactcg tgcccttttg aacaacatgg ttgttggtgt atcagaagga ttcaagaaag
    50161 aacttgaaat gcgtggggtt ggttaccgtg cacagcttca aggatctaaa cttgttttgg
    50221 ctgttggtaa atctcatcca gacgaagttg aagctccaga aggaattact tttgaacttc
    50281 caaacccaac aacaatcgtt gttagcggaa tttcaaaaga agtagttggt caaacagctg
    50341 cttacgtacg tagccttcgt tcaccagaac catataaagg taaaggtatc cgttacgttg
    50401 gtgaattcgt tcgccgcaaa gaaggtaaaa caggtaaata atgttgagtg gttgatcatc
    50461 aaccaccaac ctattttcca actttgtgca tagcacacga tttaaaacta aagaggtgaa
    50521 aactgtgatt tcaaaaccag ataaaaacaa actccgccaa aaacgccacc gtcgcgttcg
    50581 cggaaaactc tctggaactg ctgatcgccc acgtttgaac gtattccgtt ctaatacagg
    50641 catctacgct caagtgattg atgacgtagc gggtgtaacg ctcgcaagtg cttcaactct
    50701 tgataaagaa gtttcaaaag gaactaaaac tgaacaagcc gttgctgtcg gtaaactcgt
    50761 tgcagaacgt gcaaacgcta aaggtatttc agaagtggtg ttcgaccgcg gtggatatct
    50821 atatcacgga cgtgtgaaag ctttggctga tgcagctcgt gaaaacggat tgaaattcta
    50881 ataggaggac actagaaaat ggcatttaaa gacaatgcag ttgaattaga agaacgcgta
    50941 gttgctgtca accgtgttac aaaagttgtt aaaggtggac gtcgtcttcg tttcgcagct
    51001 cttgttgttg ttggtgacca caatggtcgc gtaggatttg gtactggtaa agctcaagaa
    51061 gttccagaag caatccgtaa agcagtagat gatgctaaga aaaacttgat cgaagttcct
    51121 atggttggaa caacaatccc acacgaagtt ctttcagaat tcggtggagc taaagtattg
    51181 ttgaaacctg ctgtagaagg ttctggagtt gccgctggtg gtgcagttcg tgccgttgtg
    51241 gaattggcag gtgtggcaga tattacatct aaatcacttg gttctaacac tccaatcaac
    51301 attgttcgtg caactgttga aggtttgaaa caattgaaac gcgctgaaga aattgctgcc
    51361 cttcgtggta tttcagtttc tgatttggca taagaaaggg gataaaatgg ctcaaattaa
    51421 aattactttg actaagtctc caatcggacg cattccatca caacgtaaaa ctgttgtagc
    51481 acttggactt ggcaaattga acagctctgt tattaaagaa gataacgctg ctatccgtgg
    51541 tatgatcaca gcagtatctc acttagtaac agttgaagaa gtaaactaat gaagttttag
    51601 gggatgtgca ctgtaccatc ccctaaaact agatatagtc atctatgatg acatcgtata
    51661 ggcgagttga tgggggagac aaccttttct cccttatcgg cgctagcatt ttacaaaaga
    51721 ggagaaaata aaaatgaaac ttcatgaatt gaaacctgca gaaggttctc gtaaagtacg
    51781 taaccgcgtt ggtcgtggta cttcatcagg taacggtaaa acatctggtc gtggtcaaaa
    51841 aggtcaaaaa gctcgtagcg gtggcggagt tcgccttggt tttgaaggtg gacaaactcc
    51901 attgttccgt cgtcttccaa aacgtggatt cactaacatc aacgctaaag aatacgcaat
    51961 tgtgaacctt gaccaattga acgtctttga agatggtgct gaagtaactc cagttgttct
    52021 tatcgaagca ggaattgtta aagctgaaaa gtcaggtatt aaaattcttg gtaacggtga
    52081 gttgactaag aaattgactg tgaaagcagc taaattctct aaatcagctg aagaagctat
    52141 cactgctaaa ggtggttcag tagaagtcat ctaagagagg tgacctatgt tttttaaatt
    52201 attaagagaa gctcttaaag tcaagcaggt tcgatcaaaa attttattta caatttttat
    52261 cgttttggtc tttcgtatcg gaactagcat tacagttcct ggtgtgaatg ccaatagctt
    52321 gaatgcttta agtggattat ccttcttaaa catgttgagc ttggtgtcgg ggaatgccct
    52381 aaaaaacttt tcgatttttg ccctaggagt tagtccctat atcaccgctt ctattgttgt
    52441 ccaactcttg caaatggata ttttacccaa gtttgtagag tggggtaaac aaggggaagt
    52501 aggtcgaaga aaattgaatc aagctactcg ttatattgct ctagttctcg cttttgtgca
    52561 atctatcggg attacagctg gttttaatac cttggctgga gctcaattga ttaaaactgc
    52621 tttaactcca caagtttttc tgacgattgg tatcatctta acagctggta gtatgattgt
    52681 cacttggctg ggtgagcaaa ttacagataa gggatacgga aatggtgttt ccatgattat
    52741 ctttgccggg attgtttcct caattccaga gatgattcag ggcatctatg tggactactt
    52801 tgtgaacgtc ccaagtagcc gtatcacttc atctatcatt ttcgtaatca ttttgattat
    52861 tactgtattg ttgattattt actttacaac ttatgttcaa caagcagaat acaaaattcc
    52921 aatccaatat actaaggttg cacaaggtgc tccatctagc tcttaccttc cgttaaaggt
    52981 aaatcctgct ggagttatcc ctgttatctt tgccagttcg attactgcag cgcctgcggc
    53041 tattcttcag tttttgagtg ccacaggtca tgattgggct tgggtaaggg tagcacaaga
    53101 gatgttggca actacttctc caactggtat tgccatgtat gctttgttga ttattctctt
    53161 tacattcttc tatacgtttg tacagattaa tcctgaaaaa gcagcagaga gcctacaaaa
    53221 gagtggtgcc tatatccatg gagttcgtcc tggtaaaggt acagaagaat atatgtctaa
    53281 acttcttcgt cgtcttgcaa ctgttggttc cctcttcctt ggtgtgattt ccattttacc
    53341 gattgcagct aaagatgtat ttggtctttc tgatgttgtt gcctttggtg gaacaagtct
    53401 cttgatcatt atctctacag gtatcgaagg aatcaagcaa ttggaaggtt acctattgaa
    53461 acgtaagtat gttggtttca tggacagaac agaataaaag tatttactga atcagtaaat
    53521 actgagggag tggaggttta aactctgaca tttgtaagag ttggatctcc cctcttctat
    53581 tttgttttta aataggggtg aaaagacttt ttgcttctat ttaaaaataa aataaggaga
    53641 tcaaatcatg aatcttttga ttatgggctt acctggtgca ggtaagggaa ctcaagcagc
    53701 aaaaatcgta gaacaattcc atgttgcaca tatctcaaca ggtgatatgt tccgcgctgc
    53761 aatggcaaat caaactgaaa tgggtgttct tgctaagtca tatattgaca agggtgaatt
    53821 ggttcctgac gaagttacaa atggaatcgt aaaagaacgt ctttcacaag atgatattaa
    53881 agaaacagga ttcttattgg atggttaccc acgtacaatt gaacaagctc aggccttgga
    53941 caaaacattg gctgaacttg gcattgaact agaaggtgtt atcaatattg aagtgaaccc
    54001 taacagcctt ttggaacgtt tgagtggccg tatcatccac cgcgtaactg gagaaacttt
    54061 ccacaaggtc tttaacccac cagttgacta taaagaagaa gattactacc aacgtgaaga
    54121 tgataagcct gagacagtaa aacgtcgttt ggatgttaat attgctcaag gagaaccaat
    54181 cattgctcac taccgtgcca aaggtttggt tcatgacatc gaaggtaatc aagatatcaa
    54241 tgatgtcttc tcagatattg aaaaagtatt gacaaatttg aaataaagcg tttttcacac
    54301 ttgccaaaat ccgctacaaa tgttatactg agatagtctg acttataatt gttgtctctg
    54361 tgtctagagg catcgaatcg aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg
    54421 attgaagttg aaggcaaagt agttgataca atgccgaatg caatgtttac ggttgaactt
    54481 gaaaatggac atcagatttt agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt
    54541 attttagcgg gagatcgtgt tactgtcgaa atgagtccat atgacttgac acgtggacgt
    54601 atcacttacc gctttaaata atcgaaaaac ttggagggat aagaaatgaa agtaagacca
    54661 tcggtcaaac caatttgcga atactgtaaa gttattcgtc gtaatggtcg tgttatggta
    54721 atttgcccag caaatccaaa acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca
    54781 tggctcgtat tgctggagtt gatattccaa atgacaaacg cgtagtaatc tcattgactt
    54841 atgtttatgg tatcggactt gcaacatcta agaaaatttt ggctgctgct ggaatctcag
    54901 aagatgttcg tgtacgtgat cttacatcag atcaagaaga tgctatccgt cgtgaagtgg
    54961 atgcaatcaa agttgaaggt gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga
    55021 tggaaatcgg ttcataccgt ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa
    55081 acactaaaaa caacgctcgc actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa
    55141 aataatatag gaggtaaaag tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa
    55201 tatcgaatct ggtattgctc atattcacgc tacatttaat aacactattg ttatgattac
    55261 tgatgtgcat ggtaatgcaa ttgcttggtc atcagctggt gctcttggtt tcaaaggttc
    55321 tcgtaaatct acaccattcg ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca
    55381 agaacacggt cttaaatcag ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc
    55441 agctattcgt gcgcttgctg ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc
    55501 agtgccacac aatggtgctc gtcctccaaa acgtcgccgt gtataatcat cgcattacac
    55561 tgcttttcgt ttaagaggga gtaactaaat gatcgagttt gaaaaaccaa atataacaaa
    55621 aattgatgaa aataaagatt atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg
    55681 tacaactctt ggtaactctc ttcgtcgtgt acttctagct tctctaccag gagcagctgt
    55741 gacatctatc aacattgatg gtgtgttaca tgagtttgac acagttccag gtgttcgtga
    55801 agacgtgatg caaatcattc tgaacattaa aggaattgca gtgaaatcgt acgttgaaga
    55861 cgaaaaaatc atcgaactgg atgttgaagg tcctgctgaa gtaacagctg gtgacatttt
    55921 gacagatagc gatattgaaa ttgtaaatcc agatcattat ctctttacaa tcggtgaagg
    55981 ttcttctcta aaagcgacta tgactgttaa cagtggtcgt ggatatgtac ctgctgatga
    56041 aaataaaaag gataatgcac cagttggaac acttgctgta gattctattt atacaccagt
    56101 tacaaaagtc aactatcaag tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa
    56161 attaaccctt gaaatcttga caaatggaac aattattcca gaagatgctt tagggctttc
    56221 agcacgtatt ttgacagaac atcttgattt gtttacaaat cttactgaga ttgctaagtc
    56281 aactgaagtg atgaaagaag ctgatactga atctgacgac cgtattttag atcgtacgat
    56341 tgaggaactg gacttgtctg tgcgttcata caactgttta aaacgtgccg gtatcaatac
    56401 tgtgcatgat ttgacagaaa aatctgaagc agagatgatg aaagtacgaa atcttggacg
    56461 caagagtttg gaagaagtga aactcaaact cattgatttg ggtcttggat taaaagataa
    56521 ataaaggagg aatacatggc ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca
    56581 atgcttcgcg atttgacaac tgaccttttg atcaacgaat caatcgtgac aactgaagct
    56641 cgtgctaaag aaatccgtaa aactgttgaa aaaatgatta ctctaggtaa acgtggtgat
    56701 ttgcatgcac gtcgtcaagc agctgctttc gtacgtaatg aaatcgcatc tgaaaactat
    56761 gatgaagcaa ctgataagta cacttctact acagcacttc aaaaattgtt ctcagaaatc
    56821 gcacctcgtt atgctgaacg taacggtgga tacactcgta tccttaaaac tgaaccacgt
    56881 cgtggtgatg cagcgccaat ggcgatcatc gaattagtat aaaatcatca attttgttga
    56941 gtgttatgat gatggagtct tgtgctctta gtctagctct ggtctaccgc taggatttcg
    57001 gtcctagcgg gaacactcat cataagttgg gatagtagac gcttgtttac gaaattgttt
    57061 ttttcttaag aacaacttcg taagcaggcg tttttgagta ttttcgttag aattatgcta
    57121 tactatttga aaagaatcct gtttaatgtt aaggtttctt attttaagaa gaattggagt
    57181 ttgcttatga aagcgattat aactgttgtt ggtaaagata aatctggaat tgttgcaggt
    57241 gtttctggta aaattgcaga attaggattg aatattgacg atatctctca aactgtcttg
    57301 gatgaatatt ttacgatgat ggctattgta tctagtgatg aaaagcaaga ttttacctat
    57361 cttcgtaatg aatttgaagc ttttgggcaa actttgaatg taaaaatcaa tattcagagt
    57421 gcagcgattt tcgaagctat gtataatatc taggaggtta tcatggatat tagacaagtt
    57481 actgaaacca tcgccatgat tgaggagcaa aatttcgata tcagaaccat taccatgggg
    57541 atttctcttt tggactgtat cgatccagat atcaatcgtg ctgcggagaa aatctatcaa
    57601 aaaattacga caaaggcggc taatttagta gctgttggtg atgaaattgc ggctgagttg
    57661 ggaattccta tcgttaataa gcgtgtatcg gtgacaccta tttctctgat tggggcagcg
    57721 acagatgcga cggactacgt ggttctggca aaagcgcttg ataaggctgc gaaagagatt
    57781 ggtgtggact ttattggtgg tttttctgcc ttagtacaaa aaggttatca aaagggagat
    57841 gagattctca tcaattccat tcctcgcgct ttggctgaga cggataaggt ctgctcgtca
    57901 gtcaatatcg gctcaaccaa gtctggtatt aatatgacgg ctgtggcaga tatgggacga
    57961 attatcaagg aaacagcaaa tctttcagat atgggagtgg ccaagttggt tgtattcgct
    58021 aatgctgttg aggacaatcc atttatggcg ggtgcctttc atggtgttgg ggaagcagat
    58081 gttatcatca atgtcggagt ttctggtcct ggtgttgtga aacgtgcttt ggaaaaagtt
    58141 cgtggacaga gctttgatgt agtagccgaa acagttaaga aaactgcctt taaaatcact
    58201 cgtatcggtc aattggttgg tcaaatggcc agtgagagac tgggtgtgga gtttggtatt
    58261 gtggacttga gtttggcacc aacccctgcg gttggagact ctgtggcacg tgtccttgag
    58321 gaaatggggc tagaaacagt tggcacgcat ggaacgacgg ctgccttggc cctcttgaac
    58381 gaccaagtta aaaagggtgg agtgatggcc tgtaaccagg tcggtggttt atctggtgcc
    58441 tttatccctg tttctgagga tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat
    58501 ttagaaaaac tagaagctat gacggctatc tgttctgttg gattggatat gattgccatc
    58561 ccagaagata cgcctgctga aactattgcg gctatgattg cggatgaagc agcaatcggt
    58621 gttatcaaca tgaaaacaac agctgttcgt atcattccca aaggaaaaga aggcgatatg
    58681 attgagtttg gtggtctatt aggaactgca cccgttatga gggttaatgg ggcttcgtct
    58741 gtcgacttca tctctcgcgg tggacaaatc ccagcaccaa ttcatagttt taaaaattaa
    58801 gaaaatagga gaaattttaa gttctattta agattagatg tgtatactat aatcattaaa
    58861 taaagacctc ctaatattat ttgaaacaga taacactgaa ttagtttgaa tttgattttc
    58921 atctaatatc tttatttaat gaactcctaa actttttcat aataatctcc ttcaaaagtc
    58981 gcctgtatgg gtggctttta ttttatcatt catgatataa tagaagcaaa cggaggacgg
    59041 aaaatggtaa aagtacgatt gtatttggta cgtcatggca agaccatgtt taacacgatt
    59101 ggtcgcgcgc aaggttggag cgatactccc ttaactgctg aaggtgaacg agggattcaa
    59161 gagttaggaa tcggtttgcg agaatctgat ctacagtttg agcgcgctta ttcgagtgat
    59221 tctggtcgta ccattcagac catgggaatt atccttgaag aacttggctt gcaggggaaa
    59281 atcccttatc gcatggacaa gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc
    59341 tatgatggcg atcttttcat gggcattatt cctcgtatct ttaatgtgga ccacgttcac
    59401 caattgtctt atgctgaact ggctgagggc ttggtagagg tcgatacagc tggttgggct
    59461 gaaggctggg aaaaactcag tggtcgaatc aaggaaggct ttgaaatgat tgcaaaagaa
    59521 atggaagatc aaggtggagg taacgccctt gttgtcagcc atggaatgac tattggaacc
    59581 attgtttatc tgattaatgg catgcatccg catggtctag ataatggtag cgtgacgatt
    59641 cttgaatatg aggacggtca gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag
    59701 ctaggacgtg agaagatgga agaaggctct atttaatcag tctagacttg cttgccatga
    59761 gctagggatt tgataagaat atcaagataa gaaaaaacag ccgagggtac tcctttcggc
    59821 tgtttttgat gtggaaaact aaagtgtaat gctattgctt ttagagattt tcataaacaa
    59881 gagcaaggaa cctactgtta gaacagtcag gatagttgac aaggctgcgg ctacaccgta
    59941 atttcctctg agaacctctg tataaatagc tacagtcatt gttcttgttt tgacattgta
    60001 gaggaggata gaagtagaga gttctgaaat cagtgtgacc caagatagga tggctccaga
    60061 aataatatcc gatagcatca ttggagttgt aatcttagca aagatattga gacgactact
    60121 tcctaagctt tcagcagctt cttcaatact tggtgctatt tgttgtaagc tagcaacaga
    60181 tgagcgaata gtataaggta attttctggc agatagagac ataatcaaga tgaaagcagt
    60241 ccctgtaatc ataagaaatc cacttccaaa tagaccagag aaatgaaggc aatccctaga
    60301 acggttcctg gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa
    60361 ttccgttttc taacggctag gtaggagata aatgtcgtaa atagaacaac tagaactaag
    60421 gcaatcaaag ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctagc
    60481 ttgtaactgt ttggagaata acctttaaca aataccatac ctgatgtttt taggaaagag
    60541 gtataaatta agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca
    60601 taaatggcag ccatttttcc ttttgtagtt tttttaggct caattggatg gagcagattc
    60661 atgctgaaac tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg
    60721 ataatcgcca taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa
    60781 atcaggacag ggaaagtccg atacccttcg ccaatcaaca taggcgttcc aaagtctgag
    60841 aatgctctca taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa
    60901 caaccgttac gataggttta aatccgaagg accccatgct ttcagctgct tcaagtagag
    60961 aattgtcaat actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca
    61021 gtgtaaagac aagtacaatt cctttgaatc aataaatatc gatagctgga agataaaggg
    61081 catttgtcaa aaatttagtg atgacctcat ttcgtcccag caagagaatc caggagtagg
    61141 ctcctacgaa aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc
    61201 ccttgaagtc atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga
    61261 tagtagcggt aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac
    61321 taaagaaagt gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga
    61381 gcacggtaac gataggataa acgagaaaga taggataggt aagaaagagg aagaaagagg
    61441 aagctgtcca aatatttagt tttttacgtt ccatggttga ctccttttat caggttttgg
    61501 gaaccatctg cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg
    61561 cctttttgta gatcttcttc aaaagttgat tcttcactaa cttgaatttt tgaggcaaaa
    61621 cctgtctcaa tgaaataatc cgtatttagt ccaagataga cgctatctct aatagttcct
    61681 tcaatatctc cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct
    61741 tgctcctcaa cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata
    61801 taagcgccgt cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag
    61861 gttgccacaa actcattagc tggtttatga tagagttctt ttggtcggcc gatttgttgg
    61921 atcaccccat ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg
    61981 tgggttacat aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc
    62041 atatccaagc gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt
    62101 ggattaaccg ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta
    62161 tcgggctttc gatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt
    62221 tgaatcaatt cttcttttgc ataagaccaa aagcaacgtt gtctcggaca gtcaaatgtg
    62281 ggaaaatagc gtagttttgg aaaaccatcc cgatattgcg tttgctgggt tccatattat
    62341 tgatttttgt atcatcgaag taaaattctc catctttgat actgttgaaa cctgcaatca
    62401 tacgaagaag ggtcgttttc ccacatcctg aagctccaag aagggtaaag agacttcctt
    62461 ttggaattgt aatgttcaaa ttctcaataa cagggacatc gtggtagatt tttttggcgt
    62521 taataatttt gatctcactc atagtgaacc tcttttactg tttagattgg atatctgtaa
    62581 agacttcgtt gtatttctta acgatatctg atttattctt gatgacataa tcataatctt
    62641 cagtgagtgt tttgattttg tcaattggtt tcatgttttc gcttgtttta gcatttttac
    62701 gaacaggacg gttagtagtg gttgtaccaa gtgtatcttg tacttcttga gagataataa
    62761 aatcgataaa tttcttggca ttttccatat ttttagattt tttaacgata gcagcactag
    62821 caggtaggaa gacggttcct tcttttggat agactacctt aatgttagct ccgtcattta
    62881 agagtttaac tgctggatct tcataagaga gaccaacagc catttctcca tcagcgacta
    62941 ctttatagac actagatgaa cttgaaccga ttttaccatc aataagtgtg aaaagatctt
    63001 ttacataaga ccaagcctta tcatctttgt aaccaccttg agcttgtagc atatttgtta
    63061 attgagcaaa ggcgctagaa gagtttgctg ggtcagcagt tgcgattttt ccttttagtt
    63121 caggtttgaa aagatcgtta tatccttcga tgttcatgcc tttagttaaa tcagggttga
    63181 cgattaaaac actaccatct agtgtataag gagtagagta gccagttgtg ttttgatatt
    63241 ctttgataac attatcattt tcttttgaag tatagttttc aaagagttct ccgtgggtag
    63301 tatattgtgt ataagaacca ccaaagataa catcagctac aggaacttct ttttctgact
    63361 ctagtttttt gaaaagttct ccagtaccag cttgaatcag ttctactttg ataccatatt
    63421 tttcttcaaa ggcaggaata gttgctccaa ttaagccctc tgagtttggt gaataaacga
    63481 ctagcgaacc gccgtctcct ttatcagatg aactgtcatc ggcagattca ttagaagaac
    63541 aagcagcata atacatccat ttctttttca tgatggatac ctccgttgtg ttatttaagt
    63601 ttattttaaa acaatgtaag cgtttttaaa acatacaatt ctattctata gtgtattgaa
    63661 tctataacag tacactttga ctgctaaaat atttctataa attaatttga ctttcctgat
    63721 agagatgttc acatcttatt tcaattcact atattagagt aaaattctct acaaaaagaa
    63781 gaatagccta ttttactatt cttctgagtg atttcaattc ctttggggaa atatggagat
    63841 actttttaaa tcctgacaaa tggttgtttc tttttctaaa tcggtgatac tgtatcggag
    63901 aatgcgcgtg aggtcacaaa ggctgcgata gagcttctat ggagaatttc tttttggaga
    63961 gattttttaa aggaatgaga catccgctac ctccttggaa ggtttttttg tgataagtat
    64021 agcagtttaa aaattctaga gcaaggtaaa atagaaaagg tttggctaaa attttttagc
    64081 taaacctttt gaaaagttaa gtatgtatta tagatgcttg ttatctgcaa atagctagag
    64141 catttcaagg aaataaacta gaaataacaa ttaatatggt ggttcagaaa taccttttga
    64201 taatcaataa gatcttcagg atgaagtgcg ttgattccat ccatttcata tttccgattt
    64261 aataaacgat atttgttttc accaaattga tgaaaaggga gtagttgaac ttggtcgata
    64321 tttaatgagt taaatagagt agcgaatttt tctgcatcct ctaaactatt gttaaaatta
    64381 ggaataactg ggattcttaa aacgatagtt ttattttgtg aaaaagcata atgaatgttt
    64441 ttaataatca tttgattaaa aaccccagtc acttttttat gttttataga attataatgt
    64501 tttaggtctg tgtagataaa atccacatat tgaattaaat caataaattt ttcatgatca
    64561 acaaaggcag tagtttcaat ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg
    64621 gctttagcaa attcaaactg agcaaatatt tcacctcctg ataaagttaa acctccaccg
    64681 gattcttcgt aaaattcttt gtcttttaat acctctgtaa taatttcttc tacagtcttt
    64741 tcttcaccga ctaaggtgaa tttctctcgt tgagcatctt tcattttttc aggtttcatt
    64801 ctttgagatt caggattaga acaccatgga cagcgcagag gacatccttt taaaaaaaca
    64861 gttgtacgaa tacccgggcc gtcatgaatt gaaaagtgtt gaatattaaa aataattcct
    64921 ttagatattt ccataagagt tcctcctctt cataagtcta tcctatcaca aaaacgaaag
    64981 aaaaacaatt acgaacgaaa ggttaattta ttgttttttg ctttttattt tggtagaata
    65041 aaacggaggt gtaaaatgaa aagattggaa caaattatta aattagtatc agaatatgaa
    65101 aagatcgacg ttaatacatt atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa
    65161 gatttagata aattagagtc aaaaggttta ttacacagag agcatggata tgctgtatta
    65221 aatagtggag atgacttaaa tgtacgtttg tcaattaatt atgaaattaa gagaaaaatt
    65281 gttcaggaag cagtaaaatt ggtgtcagat aatgaaacaa taatgataga atctggatcg
    65341 acctgtgctt tacttgctga ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca
    65401 aattcatttt ttatagcaaa ttttgtgaga gcttatgatt catgtcgtat tattgttctt
    65461 ggtggagagt ttcagaagga ttcacaggtt actgtgggac ctttattaaa agaaatgata
    65521 cagacttttc atgtgcatca agcttttgtt gggacagatg gttacgataa agagatgggc
    65581 tttacaggaa aagatttaat gcgcagtgag gtagttcaat atatttcagc agcgtcggat
    65641 aaagtcattg tactaactga ctcaagtaaa tttgataaaa ggggtacagt aagaagattt
    65701 gctttaagtc aagtctatga agtaataaca gacgaaaaac tttctaaaca aaatatagct
    65761 acattagaaa atgctgggat aatggttaag gtagtttcgt aagaggttaa gtgtatgaat
    65821 caagatagga ataaactgct ctctaaaatt gcttatctgt attatattga aaacttaaat
    65881 cagtcacaaa tagcagcaaa attaggaatt tatagaacct ctattagtag aatgttaaca
    65941 gaagcaagga atgcaggaat tgttaaaatt gaaatagaga attttgatac caatatgttt
    66001 aagttggaaa attatgtaaa agaaaaatat ggtctggaaa gtttagaaat tattccaaat
    66061 gaatttgatg ataatccaac aattttatct gaaagaattt ctcaagttgc agcaggtgtc
    66121 cttaggaatc taattgatga taatatgaaa attggctttt cttgggggaa aagtttaagt
    66181 aatttagtag atttaattca cagtaaaagt gtccgaaatg ttcacttcta tcctctagca
    66241 ggtggtccta gtcacataca cgctaaatac catgtgaata cactgattta tgaaatgtct
    66301 agaaaatttc atggagagtg tacatttatg aatgcaacga ttgtgcaaga aaataaattg
    66361 ttagcagatg gtattttgca atcaagatat tttgaaaatt tgaaaaatag ttggaaagat
    66421 ttagatatag ctgtagtcgg aattggtgat tttagcaata aaggaaagca tcaatggtta
    66481 gacatgctta cagaggatga ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt
    66541 tgttgtcgat tttttgattc aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg
    66601 atagcaatct ctttggaaga tttaaaaaat attcctcaaa gtttagctgt tgcttacggt
    66661 gatacgaaag tatcttcgat tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt
    66721 acagacaaaa atacaatttt aaaagttttg gaagaagatg gggatttgac ttttagagag
    66781 attctaggtg agtgaaaatg atagactgat tcagtttatc gtttttcttt ttagttgatt
    66841 gcacatttgt gcttatataa acaaaaatag tttatctgtt gtttttggat tgacaacttt
    66901 attatgtagt tgtattctat agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc
    66961 tttttacata gtgaaatgag gaggaattta tggaaatgat tgttccagat caaattatca
    67021 tgggtttaat tttatatgct ggcgatgcga aacaacatat ttataaagca ttagattaca
    67081 taaagaacgg tacatgtgaa cgatgtgaag aagaaatcca gttagctgat gcagccttat
    67141 tagaagctca taatctacaa acaaaattct tggcacagga agcgtctggt acaaagacag
    67201 aaattacagc tctctttgtt cattcacaag atcatctcat gactagtatg acggagatta
    67261 atttaatcaa agaaattatt agtttgagaa aagaacttca taaaaaataa tactagagta
    67321 ttatcattgt tattaacata gaggaggaaa acataatggt gaagattggt ttgttttgtg
    67381 cagcaggttt ttctactggt atgcttgtaa ataatatgaa aattgcagcg caatctagtg
    67441 gagttgaggc agaaatagag gcgttttctc agtctaaatt agcggattat gcgccaaata
    67501 tagatgttgc actattgggt ccacaagttg cttatacatt agataaatca aaagaaattt
    67561 gtgataagtg tgatgttccg atagctgtta ttccgatgat ggactatggt atgttagatg
    67621 ggaaaaaagt attagatttg gccctatctt tgattagtgg gtaagaaaag gagatttatt
    67681 atgtcaaaga tggatgttca gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt
    67741 ggcattatag ctctaaaaga tgggatgtta gcaattttgc cattgacagt agttggtagt
    67801 ttgttcttga ttatgggaca attgccgttc gaaggattaa ataagagcat tgctagtgtt
    67861 tttggagcta attggacaga gccgtttatg caagtatatt caggaacttt tgctattatg
    67921 ggtctaattt cttgtttttc aattgcctat tcttatgcta agaatagcgg agtagaggct
    67981 ttaccagctg gagttctatc tgtatctgca ttctttattt tgctaagatc atcttatatc
    68041 cctaaacaag gtgaggcgat tggggacgct attagtaaag tttggtttgg aggccaagga
    68101 attatcggtg ctatcattat aggtttggta gtaggaagta tttatacctt ctttataaag
    68161 agaaaaattg ttattaagat gccagaacaa gttccacaag ctattgccaa acagtttgaa
    68221 gcaatgattc cagcatttgt aattttctta tcttctatga ttgtatatat tttagcgaag
    68281 tcattgacta atggcggaac attcatagaa atgatttatt ctgctattca agttccgttg
    68341 caaggtttaa ctggatcttt gtatggtgct attggaattg cattctttat atcatttttg
    68401 tggtggtttg gtgttcatgg gcaatcggta gtaaatggag tagtgacagc tctgctttta
    68461 tctaatcttg atgctaataa agctatgtta gcctctggta atctatcatt agaaaatggt
    68521 gcacatattg ttactcaaca atttttagat tcatttttaa ttctatcagg ttcagggatt
    68581 acgtttggtc ttgtagttgc catgcttttt gcagcaaaat caaaacaata ccaagcctta
    68641 ggaaaagttg cagcttttcc agcaatattt aacgtaaatg agccagttgt atttggattt
    68701 ccgattgtca tgaatccagt tatgtttgta cctttcattc ttgttcctgt acttgcagct
    68761 gtgatagtat atggagctat tgcaacaggt ttcatgcagc cattctcagg ggtaacattg
    68821 ccttggagta caccagctat tctatcagga tttttggtgg gtggatggca aggtgttgtg
    68881 actcagttat tagtattggt gatatctaca gtggtttact ttccattctt taagatacaa
    68941 gatcgtttag cttaccaaaa tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt
    69001 aaactcacac atttgtgcta aaaattagag agttaaaatt tttctagtta aaagcttgaa
    69061 aatttctata aaaatcggta ttatattttc gaaagaaata aaaatatttt cgaaagaaag
    69121 gtgcttacga tggtaaatac agaagtagca agaacaacaa tcaagacaga atattttggc
    69181 agccttactg aaaggatgaa caaatatcga gaagatgttt taaataaaaa accttatatt
    69241 gatgctgaga gagcagttct agcaacacgc gcctatgaac gatacaagga acaacctaat
    69301 gtcctaaaac gtgcatatat gctgaaagaa attttggaaa atatgtctat ctatattgaa
    69361 gaagaatcta tgattgcggg aaatcaagct tcttccaata aagatgctcc tatttttccg
    69421 gaatatacgc tagaatttgt tctcaatgag ttggatcttt ttgaaaagcg tgatggagat
    69481 gttttctata ttacagaaga aacaaaagaa caacttagaa gtattgctcc gttttgggaa
    69541 aataataatt tacgtgctag agctggtgcc ttattacctg aagaagtgtc tgtttatatg
    69601 gaaacaggat tcttcggtat ggaaggtaag atgaattctg gagatgctca cttagcagtt
    69661 aactatcaga aacttttgca atttggttta agaggttttg aagagcgggc tcgtaaagca
    69721 aaagtagctc tagatttaac agatccagca agtattgata aatatcattt ttacgactct
    69781 atatttatcg taatcgatgc tattaaagta tatgcaaagc gctttgttgc tcttgctaaa
    69841 agtttagccg aaaatgcaaa tcctaaacgt aagaaagaat tacttgagat tgcagatatt
    69901 tgctctagag tcccatatga accggcaact acttttgcag aagctattca atcagtttgg
    69961 tttattcaat gtattttaca aattgaatct aatggccact ctctttcata tggccgtttt
    70021 gatcaatata tgtatccata tatgaaggct gatttagaaa gtggtaaaga aacagaagat
    70081 agcattgttg aacgtctgac aaatctttgg attaagacaa ttacaattaa taaggttcgc
    70141 agtcaatcac atacattttc ttcagcagga agtcctttat atcaaaatgt tacaattggt
    70201 ggacagactc gagataagaa ggatgctgtt aacccattat cttatttggt attaaaatca
    70261 gttgcacaaa cccatctacc gcaacctaat ctaactgtac gttaccatgc aggtttagat
    70321 gctcgtttca tgaatgagtg tattgaagtg atgaaacttg gttttggtat gcctgcattt
    70381 aataatgatg agattattat tccttctttt attgcaaaag gagtattgga agatgatgct
    70441 tatgattaca gtgccattgg atgtgttgaa acggcagttc cagggaaatg gggctatcgt
    70501 tgcacaggta tgagttatat gaacttccct aaggttctac ttatcacgat gaatgatgga
    70561 attgatccgg cttcgggtaa acggtttgca ccaagctttg gtcattttaa ggatatgaag
    70621 aacttttctg aattagaaaa tgcttgggat aaaacactaa gatatttgac acgaatgagt
    70681 gttattgttg aaaattctat tgatttatca ttggaacgag aagttcctga tattctatgt
    70741 tcagcattga ctgatgattg tattggtcgt ggaaaacacc ttaaagaagg tggagcagta
    70801 tatgattata tatcaggatt gcaagttgga attgcaaatt tgtcggattc gttagctgca
    70861 attaaaaaat tggtgtttga ggaagaacgt ataagcccaa gtcagctttg gcatgcactg
    70921 gaaacagatt atgccggaga agaaggtaag gtcattcaag aaatgttgat tcatgatgca
    70981 cctaagtatg gtaatgatga tgattatgct gacaaattgg ttactgctgc ttatgacatt
    71041 tatgttgatg aaattgctaa atatcctaat acacgttatg gaagagggcc tattggagga
    71101 attcgttatt caggaacatc ttctatctca gccaacgtag ggcagggacg tggaacatta
    71161 gcaactccag atggacgcaa cgcgggtaca ccgttagcag agggttgttc accatcacat
    71221 aatatggatc aacacggccc tacatctgtt ttaaaatctg tttcaaaatt accaacagat
    71281 gaaatcgtag gtggggttct cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa
    71341 gaagataaat taaaactaat tgctttgtta cgaacattct ttaatcgttt acatgggtac
    71401 catattcaat acaatgttgt ttccagagag acgttgattg acgctcagaa acatcctgaa
    71461 aaacacagag acttaattgt tcgtgttgca ggatactctg cattcttcaa tgttctttct
    71521 aaggcaaccc aagatgacat tataggacgt actgagcata cattgtaaaa taaagaggtt
    71581 ctttttatgg aatttatgct tgacacatta aatttagatg agattaaaaa gtggtctgaa
    71641 attttgccgc tagctggggt aacttcaaat cccactattg caaaaagaga gggttctatt
    71701 aatttttttg aacgaatcaa agatgtaaga gaattgattg gctctacacc ctctattcat
    71761 gttcaggtga tttctcaaga ttttgaaggc atcttaaagg atgctcatga aattcgaaga
    71821 caagcaggag atgatatatt tatcaaagta cctgttactc cggctggatt acgtgcaata
    71881 aaggtgctaa aaaaagaggg ctaccatatc actgcaacag ctatttatac agttattcag
    71941 ggattattag ctatcgaagc aggagcggat tacctagctc catattataa tagaatggaa
    72001 aatctgaaca ttgattcaaa ttctgtcatt cgtcaattag ctcttgctat tgatagacag
    72061 aactctccta gtaagatttt agctgcatcc tttaaaaatg tagcacaagt aaataatgct
    72121 ttagctgcag gtgcgcatgc tgttacagca ggagcagatg tttttgaatc agctttcgcc
    72181 atgccatcta tccaaaaggc ggttgatgat ttttctgacg attggtttgt tattcaaaat
    72241 agtcgttcca tttagataga gaggaaatac atatgagaat ttttgctagt ccttctagat
    72301 atattcaggg ggaaaatgcc ttgtttgaaa atgccaaatc aattttggat ttgggaaatt
    72361 acccgattct attatgcgat cagttggttt atgatattgt tggaaaacga tttgaagatt
    72421 acctacatag gtatggtttc catattgttc tggcgctatt taatggtgaa gcttctgaca
    72481 atgaaatcaa tcgagttgtt gccttggctg agaaagaaaa ttgtgatagt attatcggtc
    72541 ttggtggggg aaagacgatt gatagcgcaa aagctattgc agatttgatt gaaaaacctg
    72601 ttattattgc tccaacaatt gcatcgaccg atgcacctgt atctgcttta tctgttattt
    72661 atacagatga aggtgcattt gatcattatc tattttattc taaaaatcca gatttagttt
    72721 tggttgatac aaaagttatt tcacaagccc ctaagcgttt attagcgtct ggtattgcag
    72781 atggtttagc aacttgggtt gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt
    72841 tgggacaaca gcaaacattg gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt
    72901 ttgcagatgg tttacaggct atggcagctt gtgaagctaa agtggtgaca ccagcattag
    72961 aaaacattgt tgaagctaat actttattga gtggtttagg ttttgaaagt ggaggattag
    73021 ctgcggcgca tgcaattcat aatggtttta ctgcattgac aggtgacatt catcatttaa
    73081 cacatggtga aaaagtagct tatggaactt tagtacaact attattggaa aatagaccta
    73141 aagaagaact tgataagtat attgagtttt acaaaaaaat tggtatgcca acaactctaa
    73201 aagaaatgca tttggatcaa gttggatatg atgatttaat aaaagttggt aaacaagcaa
    73261 ctatggaggg tgagacaatt catcagatgc cgtttaagat ttcgccttca gatgttgctc
    73321 aagctattat cgctgtagat gcctatgtaa attcaaaata aacaataagg actactgttt
    73381 tccaaatggt agt
//
LOCUS       DAVKZI010000004        70403 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKZI010000004 DAVKZI010000000
VERSION     DAVKZI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.004"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..182
                     /locus_tag="VXB18_000311"
     CDS             <1..182
                     /locus_tag="VXB18_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381594.1"
                     /translation="TGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTT
                     TPDGYRVNANGEWVG"
     gene            complement(674..823)
                     /gene="rpmG"
                     /locus_tag="VXB18_000312"
     CDS             complement(674..823)
                     /gene="rpmG"
                     /locus_tag="VXB18_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0381595.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(839..1021)
                     /gene="rpmF"
                     /locus_tag="VXB18_000313"
     CDS             complement(839..1021)
                     /gene="rpmF"
                     /locus_tag="VXB18_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0381596.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1173..1373)
                     /locus_tag="VXB18_000314"
     CDS             complement(1173..1373)
                     /locus_tag="VXB18_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0381597.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1376..2383)
                     /locus_tag="VXB18_000315"
     CDS             complement(1376..2383)
                     /locus_tag="VXB18_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0381598.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAALTHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNGNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2574..4604
                     /locus_tag="VXB18_000316"
     CDS             2574..4604
                     /locus_tag="VXB18_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0381599.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4608..4892
                     /locus_tag="VXB18_000317"
     CDS             4608..4892
                     /locus_tag="VXB18_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0381600.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELIIKICEEKGLI"
     gene            4905..6251
                     /locus_tag="VXB18_000318"
     CDS             4905..6251
                     /locus_tag="VXB18_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0381601.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            6255..7112
                     /locus_tag="VXB18_000319"
     CDS             6255..7112
                     /locus_tag="VXB18_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0381602.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            7109..8041
                     /locus_tag="VXB18_000320"
     CDS             7109..8041
                     /locus_tag="VXB18_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0381603.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGLFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTVFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     KRFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8274..9977
                     /gene="ilvD"
                     /locus_tag="VXB18_000321"
     CDS             8274..9977
                     /gene="ilvD"
                     /locus_tag="VXB18_000321"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0381604.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10093..10173)
                     /locus_tag="VXB18_000322"
                     /pseudo
     CDS             complement(10093..10173)
                     /locus_tag="VXB18_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10231..10572)
                     /locus_tag="VXB18_000323"
     CDS             complement(10231..10572)
                     /locus_tag="VXB18_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0381605.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10696..11547
                     /gene="rgg"
                     /locus_tag="VXB18_000324"
     CDS             10696..11547
                     /gene="rgg"
                     /locus_tag="VXB18_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0381606.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSAFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11740..12987
                     /locus_tag="VXB18_000325"
     CDS             11740..12987
                     /locus_tag="VXB18_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0381607.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFVASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGIW
                     FLALSVNNFSLVVGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLFINSLGGALGGIYNIFFLSHPLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFL
                     TLYVSGKVSPKISTMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGISLLAIILTGLNLKNDI"
     gene            13065..14354
                     /locus_tag="VXB18_000326"
     CDS             13065..14354
                     /locus_tag="VXB18_000326"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0381608.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISKNFSEIFEKLGFYTQ"
     gene            14351..14428
                     /locus_tag="VXB18_000327"
                     /pseudo
     CDS             14351..14428
                     /locus_tag="VXB18_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14695..15009
                     /locus_tag="VXB18_000328"
     CDS             14695..15009
                     /locus_tag="VXB18_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381609.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            15019..15225
                     /locus_tag="VXB18_000329"
     CDS             15019..15225
                     /locus_tag="VXB18_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0381610.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15225..15422
                     /locus_tag="VXB18_000330"
     CDS             15225..15422
                     /locus_tag="VXB18_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381611.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15478..16158
                     /locus_tag="VXB18_000331"
     CDS             15478..16158
                     /locus_tag="VXB18_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0381612.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            16170..16811
                     /locus_tag="VXB18_000332"
     CDS             16170..16811
                     /locus_tag="VXB18_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0381613.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16829..17059
                     /locus_tag="VXB18_000333"
     CDS             16829..17059
                     /locus_tag="VXB18_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381614.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17095..17175
                     /locus_tag="VXB18_000334"
                     /pseudo
     CDS             17095..17175
                     /locus_tag="VXB18_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            17410..19173
                     /gene="aspS"
                     /locus_tag="VXB18_000335"
     CDS             17410..19173
                     /gene="aspS"
                     /locus_tag="VXB18_000335"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0381615.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            19151..20092
                     /locus_tag="VXB18_000336"
     CDS             19151..20092
                     /locus_tag="VXB18_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0381616.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20096..20179)
                     /locus_tag="VXB18_000337"
                     /pseudo
     CDS             complement(20096..20179)
                     /locus_tag="VXB18_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            complement(20213..20293)
                     /locus_tag="VXB18_000338"
                     /pseudo
     CDS             complement(20213..20293)
                     /locus_tag="VXB18_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20429..21415)
                     /locus_tag="VXB18_000339"
     CDS             complement(20429..21415)
                     /locus_tag="VXB18_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0381617.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21425..22225)
                     /locus_tag="VXB18_000340"
     CDS             complement(21425..22225)
                     /locus_tag="VXB18_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0381618.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22478..23320)
                     /locus_tag="VXB18_000341"
     CDS             complement(22478..23320)
                     /locus_tag="VXB18_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0381619.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23322..24614)
                     /locus_tag="VXB18_000342"
     CDS             complement(23322..24614)
                     /locus_tag="VXB18_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0381620.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24725..25996)
                     /locus_tag="VXB18_000343"
     CDS             complement(24725..25996)
                     /locus_tag="VXB18_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0381621.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26547..28064
                     /gene="malQ"
                     /locus_tag="VXB18_000344"
     CDS             26547..28064
                     /gene="malQ"
                     /locus_tag="VXB18_000344"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0381622.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28090..30348
                     /gene="glgP"
                     /locus_tag="VXB18_000345"
     CDS             28090..30348
                     /gene="glgP"
                     /locus_tag="VXB18_000345"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0381623.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTSTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31393..31965)
                     /locus_tag="VXB18_000346"
     CDS             complement(31393..31965)
                     /locus_tag="VXB18_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381624.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNRRINF"
     gene            complement(32764..33612)
                     /locus_tag="VXB18_000347"
     CDS             complement(32764..33612)
                     /locus_tag="VXB18_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0381625.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTITILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33764..34042
                     /locus_tag="VXB18_000348"
     CDS             33764..34042
                     /locus_tag="VXB18_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381626.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            34044..36107
                     /locus_tag="VXB18_000349"
     CDS             34044..36107
                     /locus_tag="VXB18_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0381627.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQSVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36185..37441)
                     /locus_tag="VXB18_000350"
     CDS             complement(36185..37441)
                     /locus_tag="VXB18_000350"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0381628.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37583..40048
                     /locus_tag="VXB18_000351"
     CDS             37583..40048
                     /locus_tag="VXB18_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0381629.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            40113..41024
                     /locus_tag="VXB18_000352"
     CDS             40113..41024
                     /locus_tag="VXB18_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0381630.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41254..41952
                     /gene="dapD"
                     /locus_tag="VXB18_000353"
     CDS             41254..41952
                     /gene="dapD"
                     /locus_tag="VXB18_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0381631.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            42020..43150
                     /locus_tag="VXB18_000354"
     CDS             42020..43150
                     /locus_tag="VXB18_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0381632.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGIFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43162..43701
                     /locus_tag="VXB18_000355"
     CDS             43162..43701
                     /locus_tag="VXB18_000355"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0381633.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43685..44362
                     /locus_tag="VXB18_000356"
     CDS             43685..44362
                     /locus_tag="VXB18_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0381634.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(44465..45397)
                     /locus_tag="VXB18_000357"
     CDS             complement(44465..45397)
                     /locus_tag="VXB18_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381635.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(45815..46714)
                     /gene="galU"
                     /locus_tag="VXB18_000358"
     CDS             complement(45815..46714)
                     /gene="galU"
                     /locus_tag="VXB18_000358"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0381636.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(46736..47752)
                     /locus_tag="VXB18_000359"
     CDS             complement(46736..47752)
                     /locus_tag="VXB18_000359"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0381637.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            47964..48344
                     /locus_tag="VXB18_000360"
     CDS             47964..48344
                     /locus_tag="VXB18_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0381638.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(48518..48943)
                     /locus_tag="VXB18_000361"
     CDS             complement(48518..48943)
                     /locus_tag="VXB18_000361"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0381639.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(49011..49661)
                     /gene="phoU"
                     /locus_tag="VXB18_000362"
     CDS             complement(49011..49661)
                     /gene="phoU"
                     /locus_tag="VXB18_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0381640.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(49676..50428)
                     /gene="pstB"
                     /locus_tag="VXB18_000363"
     CDS             complement(49676..50428)
                     /gene="pstB"
                     /locus_tag="VXB18_000363"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0381641.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(50430..51245)
                     /gene="pstA"
                     /locus_tag="VXB18_000364"
     CDS             complement(50430..51245)
                     /gene="pstA"
                     /locus_tag="VXB18_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0381642.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(51238..52101)
                     /gene="pstC"
                     /locus_tag="VXB18_000365"
     CDS             complement(51238..52101)
                     /gene="pstC"
                     /locus_tag="VXB18_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0381643.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     IYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(52219..53094)
                     /locus_tag="VXB18_000366"
     CDS             complement(52219..53094)
                     /locus_tag="VXB18_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0381644.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(53261..54592)
                     /locus_tag="VXB18_000367"
     CDS             complement(53261..54592)
                     /locus_tag="VXB18_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0381645.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(54593..55300)
                     /locus_tag="VXB18_000368"
     CDS             complement(54593..55300)
                     /locus_tag="VXB18_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0381646.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKT
                     PQFIRTIRGYGYKFKEL"
     gene            complement(55384..55869)
                     /locus_tag="VXB18_000369"
     CDS             complement(55384..55869)
                     /locus_tag="VXB18_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0381647.1"
                     /translation="MAPTDKEDLIRTLELAPHVKGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWESTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            55855..56413
                     /locus_tag="VXB18_000370"
                     /pseudo
     CDS             55855..56413
                     /locus_tag="VXB18_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(56728..58419)
                     /locus_tag="VXB18_000371"
     CDS             complement(56728..58419)
                     /locus_tag="VXB18_000371"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0381648.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNTQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NEDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            58555..59001
                     /gene="argR"
                     /locus_tag="VXB18_000372"
     CDS             58555..59001
                     /gene="argR"
                     /locus_tag="VXB18_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0381649.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            59052..61586
                     /gene="mutS"
                     /locus_tag="VXB18_000373"
     CDS             59052..61586
                     /gene="mutS"
                     /locus_tag="VXB18_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0381650.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTVLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLRYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEHISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            61733..63427
                     /gene="patA"
                     /locus_tag="VXB18_000374"
     CDS             61733..63427
                     /gene="patA"
                     /locus_tag="VXB18_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0381651.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(63757..64020)
                     /locus_tag="VXB18_000375"
                     /pseudo
     CDS             complement(63757..64020)
                     /locus_tag="VXB18_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            64218..65984
                     /gene="patB"
                     /locus_tag="VXB18_000376"
     CDS             64218..65984
                     /gene="patB"
                     /locus_tag="VXB18_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0381652.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVSDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFK"
     gene            66123..66812
                     /locus_tag="VXB18_000377"
     CDS             66123..66812
                     /locus_tag="VXB18_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0381653.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            66816..66995
                     /locus_tag="VXB18_000378"
     CDS             66816..66995
                     /locus_tag="VXB18_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381654.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            66982..68331
                     /locus_tag="VXB18_000379"
     CDS             66982..68331
                     /locus_tag="VXB18_000379"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0381655.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            68455..69915
                     /locus_tag="VXB18_000380"
     CDS             68455..69915
                     /locus_tag="VXB18_000380"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0381656.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQIKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            69929..70363
                     /locus_tag="VXB18_000381"
     CDS             69929..70363
                     /locus_tag="VXB18_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0381657.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT        20678 a        13068 c        15130 g        21527 t
ORIGIN      
        1 ctactggttg ggttaaagac aaaggcttat ggtattactt aaatgaatca ggttcaatgg
       61 ctactggttg gtttacagtt tctggtaaat ggtactatac ctataattca ggagatttat
      121 tagtaaacac gactacaccc gatggctatc gagtcaatgc taacggtgag tgggtaggat
      181 aggtatccat tagctaaatc taatcattct gaactaaaaa atcttcttac atatgtagga
      241 agattttttg gattctcaaa actagtttaa aagactacgc tatttaaacc aattttaaga
      301 atggatatat aaggatattc agaaatctag ttggtcaact tttgtatttt gaatatacct
      361 tagatggtga cgatgtcttg gtatatctgg tactcactta catattctaa cttattttaa
      421 ctaagataca actgtagttg gtgaatttgc tacaaatagt gtagaggcgt tatttgaaaa
      481 atatacaaaa aaggaacccc aacttacatt tgagtttctc ttacttttaa tcgtccgaat
      541 ccgtattctt atttcaaaaa aggtagtgaa aaaggtagtc attcgaatga tttcccttgc
      601 aatatagtga aattaacaaa aagaaaaaac gctgatcaag cgtttttctt ctgtattgat
      661 tcgtattgaa tgcttacttc acttctgtaa acacaacgtg tttgcgaagt tttggtgagt
      721 atttcttcaa ttgaaggcgg tctggagtgt tacgtttgtt tttagaagta aggtacaagc
      781 gttcaccaga ttctttgtgt tcaagtgtaa tatttacgcg catggtatct cccttctatt
      841 attcagctga tgcagcttta gcgattttac gtcctttgta gtatccttta agtgatacac
      901 ggtgagaacg tgagtaatct ccagtagttt cgtcaaagtt tacagatgga gctgttactt
      961 tgtagtgtgt acgacgtttg tttttcttcg cttttgaagt gcgacgtgca ggtactgcca
     1021 ttttgatttc tcctttaggt atttatattc gattcaatct actgattttc atcaaccata
     1081 ctaggataac acattttttt tgtaaagtaa agttacttga caaaaaaaga tgaaaaaatt
     1141 ctcctatccg acacggcaga caggagaaga tgttaaatat caatctcaaa tggctcgtca
     1201 atggtttctg atacgtattt tccgtctttt ttccgttgct tgacacactc tgtgaggaga
     1261 tattcgattt gcccattgac tgaacgaaag tcgtcttctg cccatgatgc gagtgcagcg
     1321 tataactttg ttgagagtcg aagggggatc tgcttttttt tagcttcagc catctttagt
     1381 aaagacttcc tgtgttgaca attggttgtg catcatgatt gccacaaaga acgacaagga
     1441 gatttgaaac catggcagct tttcgttctt cgtcaagttc taccaattcc ccttcattga
     1501 gccgttctag tgccatttca accattccta cagcaccatc tacaatcatc ttccgtgcat
     1561 caataatggc agatgcttgt tggcgttgaa gcataacggc agcaatttct ggagcataag
     1621 ctaggtaagt gatacgtgct tcaaggattt ccaagccagc atcctcaaca cgactttgga
     1681 tttcttcacg aatacggtta gcaacaattt cgctagagcc acggagacta ccttcatctg
     1741 cttgcccgtc acccgtagta tccacattag gagacacatc gtaaggatag atgcggacaa
     1801 tattacggag ggcgctatca cattgcaatg aaagatattc tttgtagtta tcaacgttga
     1861 agactgcctt agcggtatcg acaactctcc aagttaccgc gataccgatt tctacagggt
     1921 ttcctaagca atcattgatt ttttgacgag aattgctcaa ggtcatgact ttgagggaaa
     1981 tgtgtttctt gccaatttca agatttacat cattgccatt tgatgattta gctcctaaaa
     2041 aaggagattt tgtgctaaca tcaccacttt gtccaagtcg agtgtggttt gcagggttga
     2101 ctgctacgct gaagggattg acaaagtaaa agccaggttc tttgatggta cctgtatagt
     2161 taccaaagag tgtcagaacc agagcctcct gaggtttgac aacttttaaa ccagcatgag
     2221 ttagcgctgc aattacgatt agtaaaggtc cgataataat tccaaaaatg ttttccgaac
     2281 caacacccat tataaatata aagacaccaa gtacgagcgt caattcaatg agaatcaatg
     2341 cgaatacacc atttggtttt gaattgatta gtttttcagt cataagaatg acctcccatt
     2401 atttgatatc taaatgatat cactttgttt ttaaaagtca atagaaagtt gaaaataatc
     2461 actaaaaagt ttcagcccaa taatttcttt taaaaggtga gattatattg tgctcaaata
     2521 ctcttttatt cttataattt ttacactata attgtagtta gaaaggaaga gaaatgtttg
     2581 attatagagc actagttatt ttgatgactt tgatggatca ttgtgagcta tcattatatg
     2641 aattatctgt taaggtgagc ttacctataa aggaagtcaa agaaggaata gattatttag
     2701 tgccttatct agctaataaa gggatagtgc tggataaaaa acaaggtcga tatagtttat
     2761 caaatcgtac gaagcagtct ttgacagata ttattaagtc ggatgaattg gttttaccaa
     2821 agtcgactcg cttagcttta atctatcttt acactttttg ccgattagat tttatatcga
     2881 ataatcatta ccaagacttt ttgaaagtaa gtaagaatac aaccttatct gatattcaat
     2941 cattaagaaa gattatgtta gataatgatt tggagctagg gtacagtaga gcaaaaggtt
     3001 atactttaca cggttcagag tggaataagc accgtttagc ttttcaaatg gttagtgagt
     3061 tgctggaatc ctccataggg atttggggtt tggattatgt tttatccagt tgggggtatt
     3121 cattaactta tgatttgatt gatcaggtag ttaaagatta ttatgagaag ctacagctag
     3181 tacctattgt taatcaatta aaagtttacc ttttcggttt agtattcatt ctgtgtaggt
     3241 atcaaaggga tgttgaaaga gtatgtcttt cagagacatt agtatctcct gttattcaag
     3301 atataaccac tattttattg gatacagtgg ttgatttggg aattatagat acggtgtttt
     3361 ctgaggatga ttatcgctat atcaccgttt tattatcaag ttgctttgaa ggtgaagtag
     3421 atgttgctcc ggtttacttt aatcaattaa cagaggctat tataagtaga atggaagata
     3481 tttctttgtt acattttaaa caaagggaag gattgagaga aaatcttcgc cgccacctta
     3541 taccggctta ctatagatta aagttcggcc tacctagttc aaatgaatat gtattgcatg
     3601 ttaaagaaca ttatcctgat ttatttgaat tagtcaaaga ttctttgatg cccttgatgg
     3661 acgctattga caatcccata cctgatagtg aaacagcata ttttgttatc catttcggag
     3721 gttatttaaa gaaagcagat actttgcctc aaaaatgcta taaagcagca atcatttgtc
     3781 ctaatggtgt tagttcttca ttgatgttaa aagagaatct attagcatta tttcctcaaa
     3841 ttgagtttat aggaacctca aagattgatg atttacaggt gaaagctagt agtgactatg
     3901 atatggtttt ttctaccata aaagtggaga cagaaaagcc aaattatcta gtttcggtta
     3961 tgatgactga agagcaagca atacaactag tagaactagt gttaaaagat tttccgaatt
     4021 tagagtatgg agattttgag attgaacaaa tcctgaatat tgtcaaaaga tatggaatta
     4081 ttacacaaga attggaatta agattggcgt taaagaatta tctttatcaa aaaaatgata
     4141 gaaaggaaat tgtaccagtg ctagaacaac ttattaccaa agaaacctat caggttagtt
     4201 cgcaaaaatt aggatggaag gaggcgattc gtttagcagc taaaccgctt ttggatcaag
     4261 ataagataac tgagaactac cctgaggcaa tgattcaaaa agtagaagag tttggacctt
     4321 ttattaattt agggaaggga gtagcaattc ctcacgctcg gccagatgaa ggtgtgaatg
     4381 aaataggaat gtcaatgtta gttttggaag aaccgattta tttattggat aatccagaac
     4441 aagaggtaag attgttgatt tgtattgcag ccattgataa tgagagtcat ttaaaggctt
     4501 tgtcacattt aacaacaatt ttaagagata aaaatcatgt tcaaacttta atatcatcaa
     4561 aaaactatga tgatattaaa atgataatta aacaggagga ttagataatg ttaaaaattg
     4621 gtacagcttg tggttcagga ttaggttcaa gttttatggt acagatgaat attgaatctg
     4681 tattgagtga tttgaatgtt tcggatgtag aagttgaaca ttatgattta ggtggagcag
     4741 atccaaatgc agctgatatt tggattgttg gtcgtgatct agctgattca gctagtcatc
     4801 ttggagatgt tcgtatctta aatagtatta ttgatatgga cgaactacga gaattaatta
     4861 ttaaaatttg tgaagaaaaa ggacttatat aggaggctag cgtcatgatg aagttcatat
     4921 tggatattgt tagtacacca gctattttag tagctttaat tgcaatttta ggattagttc
     4981 ttcagaagaa gaaattacct gatattatta aaggtggaat taagaccttt gttggtttct
     5041 tagttgtatc tggtggtgca ggaattgtac aaaattcttt aaatccattt ggtaccatgt
     5101 ttgagcatgc ttttcattta tctggcgttg tgccgaataa tgaagcaatt gtagctgtag
     5161 ctttaacaac atatggctca gctactgcaa tgattatgtt tgcaggcatg gtgttcaata
     5221 tcttaatcgc tcgttttact cgatttaaat atatcttttt aacagggcac cacactctat
     5281 atatggcgtg tatgattgcg gtcattttat cagttgctgg ctttactagc ttgcctctta
     5341 tcttactagg aggattagca ctcggtatta ttatgagtat ttccccagca tttgtgcaaa
     5401 aatatatggt tcaattaact ggaaatgaca aggtggcttt aggtcatttc agttctttgg
     5461 gatattggtt gagtggtttt actggtagcc ttatcggtga caaatcaaaa tcaacagagg
     5521 acattaaatt tccaaagagt ttagcttttt tacgtgatag tactgttagt atcactttat
     5581 ctatggcagt tatttacatt attgtagcta tctttgcagg gtcagaatat atagaaaaag
     5641 aaatcagtag tggtacaagt ggtctagttt atgctttaca attagcaggt caatttgcag
     5701 caggggtatt tgttatttta gcaggtgttc gccttatttt gggcgaaatt gttccagcct
     5761 ttaaaggtat ttcagagcgt cttgtaccta attcaaaacc tgctttggat tgtccgattg
     5821 tttatactta tgcacccaat gcagttctaa ttggatttat ctctagtttt gttggtggtt
     5881 tagtaagtat ggcaattatg attgcttcag gaacggttgt tatcttacca ggcgttgtgc
     5941 ctcatttctt ctgtggagcg actgcaggtg tcattgggaa tgcatctggt ggtgttcgtg
     6001 gagccactat tggagcattt ttacaaggta ttttaatcag ttttcttcca gtctttttaa
     6061 tgccagtttt gggaggactt ggtttccaag gatcaacttt ctcagatgca gattttggtc
     6121 tatcaggaat tattttagga atgttaaatc aatttggctc acaagcaggc attgtgattg
     6181 gtcttgttct tattttagca gttatgtttg gagtatcctt tattaaaaag ccatctgcaa
     6241 aggaggaata agggatgatt ttaagtaaaa atagagaaga tgggttaaga aaatttgcga
     6301 ctaacatccg attaaatact cttagaacat tgaatcatct tggattcgga cattacggag
     6361 gaagtttgtc tatcgtagaa gttttagcag tgctttatgg tgaaataatg ccaatgactc
     6421 cagaaatatt tgcagcacga gatagagatt atttcatatt atcaaaaggt catggaggac
     6481 cagctctata cagtacactc tatttgaatg gtttctttga caaagaattc ttatattctt
     6541 taaatacaaa tggaaccaaa ttaccgtctc atcctgatag aaatctaacg ccaggcatag
     6601 atatgacaac gggctcttta ggacaaggaa ttagtgttgc aactggactt gcatatggtc
     6661 agagaataag aaagagtccc ttttatactt acgctattgt tggagatggt gagttaaatg
     6721 agggacaatg ttgggaggct atacagtttg cttctcatca acagttatcc aacttaattg
     6781 tatttgttga tgataacaaa aaacaattag atggttttac aaaggatatt tgtaattcag
     6841 gtgatttcgt agaaaaattt tcagcatttg gatttgaatc cattagggtc aagggttcag
     6901 atattagaga aatttatgaa gggattgtcc aattaaaaca gtcaaataat tcatcaccta
     6961 agtgcattgt attagatact attaaaggtc aaggggttca agagctggaa gaaatgaaat
     7021 ccaatcatca tcttcgccct actgtagagg agaaacaaat gttaacttca gttgtagaaa
     7081 gattaagtca ggaattggag gaaacagaat gatgagaagt acgaaagaat tacggcatgt
     7141 atatagagac ttccttttag aggctaatca aagttattct gatatagtag tcttagaagc
     7201 cgatttgtca agttcgatgg ctactcataa tcttgaaaag gacttcggag accgttatgt
     7261 gaatgttggg attatggaag cagaaatggt cggccttgca gcaggcttgt ctattcaggg
     7321 gtttagacct tatcttcata catttggtct ttttgcttca cgaagagtat ttgatcaatt
     7381 atttatttct cttggatacg cacaattgga tgccactgtg attggatcag atgcaggagt
     7441 aacggcagag atgaatggtg gaacacatat gccatttgaa gaaatcggct tgttacgttt
     7501 aattcctaaa tcaatcattt ttgaagcaac tgatgatatc caatttcgtg aaatattgaa
     7561 ccagacatta gacttaaaag gactaaaata tattcgaaca attagaaaag ctccagaggc
     7621 tgtatatcaa ggtggagaag atttttctaa aggctacatt gagttaagac acggtgaaga
     7681 tgttgtaata gttgcttctg gcataatggt tgctccaagt attcgagttg cagatgaact
     7741 gtctaaatta ggttattcag taggtgtgat agatttattt agaatcaaac cgataccaga
     7801 acagataaaa acaatgttaa gtggaaaaac tgtatttact gtagaaaacc acaatcagat
     7861 aggtggaatt ggcagtgctt tatgtgaatt attctctgat gatggaataa caaaaattca
     7921 tcggatgggt gttcaaaaaa gatttggtca agtagggaaa atggattatc ttcttaatga
     7981 gtatggtttg agtgaatcga atataaaaga gaaggttcta gaaatttata atgcaagata
     8041 gatgttaaat acacttatct gaaagaattt ctgtaaaaat tacattacgt tatttaaaga
     8101 aagcggatta aaaagcatat tctggtcatc agaaagtgca ctaatccgct ttgttgtttt
     8161 taattttaaa tatttcacat gcgtatagaa ttttctgaaa attcaagaat tttattctgt
     8221 tcattgcctt taaattgtgc tataatagta aaaactgaaa tgggagggat aagatgactg
     8281 aattagataa acgtcaccgc agtagcatct atgacagcat ggttaaatca cctaaccgtg
     8341 ctatgcttcg tgcgactggt atgacagata aggactttga aacatcgatt gtgggagtga
     8401 tttcgacttg ggcggaaaat acaccatgta acattcactt gcatgatttc gggaaactgg
     8461 ctaaagaagg tgtcaaatct gcaggcgctt ggcctgtaca gtttggaacc attaccgtag
     8521 cggacgggat cgctatggga acgcctggta tgcgtttctc tctaacatct cgtgacatca
     8581 tcgcggactc catcgaggcg gctatgagtg gtcacaacgt ggatgccttc gtcgctatcg
     8641 gtggctgtga caagaacatg cctggatcta tgattgctat tgctaatatg gatatcccag
     8701 ctattttcgc ctatggtgga actattgcac cgggaaatct tgatggtaaa gatatcgact
     8761 tggtttctgt ctttgaaggt atcggaaaat ggaaccacgg tgacatgaca gctgaggacg
     8821 tgaaacgtct tgaatgtaat gcctgccctg gccctggtgg ttgtggtggt atgtatactg
     8881 ctaataccat ggcaactgct atcgaagttc tagggatgag tttgccaggg tcatcctctc
     8941 acccagctga atcagctgat aagaaagaag atatcgaagc agcaggacgt gctgttgtta
     9001 agatgttgga acttggtctc aaaccatcag atatcttgac tcgtgaagcc tttgaagatg
     9061 ctatcactgt aaccatggct ctcggtggtt ctacaaacgc cactcttcac ttgctcgcca
     9121 ttgcccatgc cgcaaatgtt gacttgtcac ttgaggactt caatacgatt caagaacgtg
     9181 tgcctcactt ggccgacttg aaaccatctg gtcagtatgt cttccaagac ctctacgaag
     9241 tcggtggtgt ccctgcggtt atgaagtact tgttggcaaa tggtttcctt cacggagatc
     9301 gcatcacatg tactggtaag actgtagctg aaaacttggc tgactttgca gacttgactc
     9361 caggccaaaa agttatcatg ccacttgaaa atccaaaacg tgcggatggt ccgcttatca
     9421 tcttgaacgg gaaccttgct cctgacggtg cagttgccaa ggtatcaggt gttaaagtgc
     9481 gtcgtcacgt tgggccagct aaggtctttg actcagaaga agatgcgatt caggccgttc
     9541 tgacagatga aatcgttgat ggcgatgtag tcgttgttcg ttttgttgga cctaaaggtg
     9601 gtcctggtat gcctgagatg ctgtcacttt catcaatgat tgttggtaaa ggtcagggag
     9661 ataaggtggc cctcttgacg gacggacgtt tctctggtgg tacttatggt ctggttgttg
     9721 gacatatcgc tcctgaagct caggatggtg gaccaattgc ctatctccgt accggcgata
     9781 tcgttacggt tgaccaagat accaaagaaa tttccatggc cgtatccgaa gaagaacttg
     9841 aaaaacgcaa ggcagaaaca accttgccac cactttacag ccgtggtgtc ctcggtaaat
     9901 atgcccacat cgtatcatct gcttcacgcg gagccgtgac agacttctgg aatatggaca
     9961 agtcaggtaa aaaataaact catactcgaa aatctcttca aatcacgtca acgtcgcctt
    10021 gccgtaggta tggttactga cttcgtcagt tctatctaca acctcaaaac agtgttttga
    10081 gctgacttcg tcagttctat ccataacttc aaaacagtgt tttgagcaac ctgcggctag
    10141 ttttctagtt tgccctttga ttttcattga gtatcaaaaa gcaagccatt ttcggcttgc
    10201 ttttttcatc tttaaaagtg attggcctgc ttaacgaggt ggtagtccaa gggcaatacg
    10261 gccatagcga ctgattcgtg tgattttcca ggcaggcgac caggtaactt caaccttgat
    10321 atctttgata ccctcgattt gtttcagacc tgccacgatt tcaataggca ggctttcggc
    10381 gcaatcacag gcagtatcgg tgaaggtcat gacaatcttg cagagccccg tttcatccag
    10441 attgatttca taaatcagac ctagattgta aacatccaat tccacatctg tatcaaaaac
    10501 tttctctagt ttttcgataa tttggtcttg caaggccaaa gcacggtcat tgattttgat
    10561 atcgtctctc atagcagtcc ctccacgtga taaatatcct ctattttctc ataattctga
    10621 caatttggca agtttttgat gaattttctg aaaaatatga taaaatgaag aaaatacgga
    10681 atcaagggga agtctatgga gcagattgga aaagtcttta gacaattacg agaatcaaga
    10741 aatatctcac tgagacaagc aaccggagga caattttcgc cgtctatgtt gtcccgtttt
    10801 gaaacaggtc agagtgagct ttcggtggaa aagtttctat ttgctctgga aaatatatct
    10861 gccagtgtgg aggagatcct ctttctggcg agaggtttcc agtatgatac agattctgag
    10921 ttgagaaaag aaattacaga tgtcttggaa ccaaagaata tagcacctct tgaggactta
    10981 tatcgcaggg agtatcaaaa gcatgcccat tctcacaaca aacagaaaca tattctaaat
    11041 gccattatga tcaagtctta tatgaagagc atggatgaaa gggtagagtt aacagcagag
    11101 gaaggaaaag tccttcatga ttatttgttt tctaccgaga tctggggaat ctatgaactc
    11161 aatttatttt cagtcagttc tgccttttta tctgtttctc tttttactag atatgtacga
    11221 gaaatggtac gtaaatctga ttttctaatg gaaatgtctg gtaatcgaaa cttttttcat
    11281 actatactat tgaatggctt tttagctagt attgagtgtg aagaatttac caatgcctat
    11341 tattttaaac gtgttatcga agagcatttc tacaaggaaa atgagaccta tttccgaatt
    11401 gtttatctgt gggcagaagg tctccttgat agcaagcaag gtagagtcaa ggaaggccag
    11461 aaaaagatgg aggatgctgt ccgtattttt gagatgcttg gctgtaataa atctgccgaa
    11521 tactatagaa atacgaccga atgttgaata tctgcaaacc aagaaaaaat ttgaagcgat
    11581 agaactattg ccctctctca ggtcattaca aaagttctat cgtttctttt tgctcatttt
    11641 atttgttgca tatattcaag agttctccct ctcaaatttc taagtgctat actatagtca
    11701 tacttcatat agaggttcga acaaggaggg agattatcta tgaaactatt gtttagaaat
    11761 ccagcttata gaattttgac tttgtcacgc ttcttcaatg cttttgttgc ttcgattttc
    11821 aacctggtct ttatcgtcta tgcatcgacc ttgtcacaag catcttttgc tgttgctatg
    11881 gcgaatattg tcatgattct tccgaccttc tttacagttt ttgcagggat tcgggcagat
    11941 tacacgaggg acaaggtcaa atggatggtc tatagcggtt tgtttcaggc ggttctattt
    12001 tttctagcag ccctagttgt tcagcaagct agtctctttg ccttttctag cctgtgtttg
    12061 atcaatgtca ttagtgatgt catcagtgat tttgcaggtg gcctgcgtat gcctcttatt
    12121 aaggaaaaag tagctgaaga tgatctgatg gaggcttatt ctttttcaca gttcatcacc
    12181 tatatttcag ctattggtgg tcaagctttc ggaatctggt tcttagctct atcggtcaac
    12241 aatttttctc tcgttgtggg aatcaatgcc tgctttttcc tagtatcagc cactatcctc
    12301 tttttaggaa aaagcaaatt gagcctgtca atgtcatctg ctgatggtga aaacttaaaa
    12361 aatgagaagc tttctatcaa agaccagttc ctaacaattt accgaaattt acgtctcgtt
    12421 tttcttaaaa gtggacagaa aaactttggt tttatgctct ttgctgtctt gtttattaat
    12481 tccttgggtg gcgctttagg tggaatttat aatatcttct ttttgagcca tcctctcttg
    12541 aatttttctt acacagaggc actatttatc aatcaattct gtgttttagt agcaatcatc
    12601 atcagtagcc ttacgggcaa tgattatttt gggaagcagt ccttgcctag attgatgatg
    12661 tgggcgaccg taggacttag tctagttggt ttggctaatt tattcaatca agtcgttctt
    12721 ggtttgctat ttctcttttt aactttgtat gtgtctggta aagtttcacc gaagattagt
    12781 accatgctca tgaaaaatct agctccagag gttctagctc gtaccagtaa ctttttaggt
    12841 ctcttgttta ccttatccat acctgtggga acagcctgtt tttcacttgt agccgtatgg
    12901 aatatacagt tgacttggat gctatttgtt ggtatttcct tgctagctat tattttgaca
    12961 ggtcttaatc tcaaaaatga tatttgaatc ctaatttttt tctcactgtt ttaatccctc
    13021 tatttatggt aaaataagac tattaagttt aaagaggatt ccctatgaaa ttacaaaaac
    13081 caaaaggaac gcaggatatt ttacctgctg aatctgccaa atggcagtac gttgagggct
    13141 ttgcccgtga aattttcaag cgctacaact acgcagaagt gcgcacgccc atttttgagc
    13201 attacgaggt tatcagtcgc tctgtcggag atacaacgga tatcgtaacc aaggaaatgt
    13261 acgatttcta tgacaagggt gaccgtcata ttaccctccg tccagaagga actgcgcccg
    13321 ttgtccgttc ctatgtggaa aataaactct tcgccccaga agtgcaaaag ccaagcaagt
    13381 tctactatat gggacctatg ttccgttatg agcgtccaca ggcagggcgc ttgcgccaat
    13441 tccaccagat tggtgttgag tgttttggct ctagcaatcc agctaccgat gtggaaacaa
    13501 tcgctatggc agcccatttt ttgaaggaaa tcggtattca aggtgtcaaa ttgcacctca
    13561 acactcttgg aaatcctgag agccgtgcag cctaccgcca agccttgatt gactatttga
    13621 caccgctcaa ggagaccttg tctaaggata gccaacgtcg cttggaggaa aatcctcttc
    13681 gtgtcttgga ctctaaggaa aaagaagaca aggtggcagt agagaatgcg ccgtctatct
    13741 tggactttct tgatgaagaa agccaagctc attttgatgc tgtgcgtcag atgttggaaa
    13801 atcttggagt agattacatc atcgatacca atatggtgcg tggtctggac tactataacc
    13861 acaccatttt cgagtttatc acagagattg agggcaatga cttgacagtc tgtgcgggtg
    13921 gtcgctacga tggtttggtt gcttactttg gaggccctga aactgctgga tttggttttg
    13981 ggcttggtgt agagcgcctg cttctcatcc ttgaaaaaca aggcgtggcc ctccctatcg
    14041 aaaatgccct agatgtctat atcgcagtct tgggtgatgg agcaaatgtc aaagccctag
    14101 aactagtcca agctcttcgc caacaaggtt tcaaagcaga gcgtgattac ctcaaccgta
    14161 agctcaaagc tcagttcaag tcagccgatg tctttgtggc taagaccctc atcaccctag
    14221 gagagagtga agtcgaaagc ggacaagtga cggtcaagaa caaccaaacc cgagaagaag
    14281 tgcaagtgtc acttgagaca atcagcaaaa atttctcaga aatctttgaa aaactaggat
    14341 tttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggtt gctcaaaaca
    14401 gtgttttgaa gttatggata gaactgatga agtcagctca aaacactgtt ttgaggttgt
    14461 ggatagaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga cgtggtttga
    14521 agagatttta gaagagtatt aatgatagat aaagtggtca ggaacttact cctgaccttt
    14581 ttcttttgca aaatgacaaa aatcataaac tttttgacaa ctatacttgt caaaaagaaa
    14641 aagatgtgtt acaatgaatt caagttaaga aataggaagc agaaaggagt tataatgtgg
    14701 gtactagtat ttatactatt tatgattttc ttttattcta ataattctaa aaaaatcaag
    14761 aaactagaga ataaaatcaa aagacttgag cgaaaagaga aaggaaacgc agaaatgtcg
    14821 agattattac aagaaatgat tggaaaggaa ccaattataa cgggagtgta tattgggcca
    14881 gataactggg aagttgtgga tgttgatgag gaatgggtaa agctacgacg tgtagataat
    14941 acgggaaaag aaaaattcaa gttgcaacgt attgaagata tccaaaccgt tgaatttgac
    15001 ggagagtagg tgtgtaacgt gcaactaaaa aatcgtctaa aagagcttcg agctcgcgat
    15061 ggtctcaatc aaaccgacct agccaaactg gcaggggttt ccagacagac cattagccta
    15121 ctagaacggg atgagtacac cccatccatt atcattgccc tgaaaatatc tcaaattttc
    15181 aacgaaacag tcgaatcggt atttcgtttg gaggaggacg agtgatgaac aagtataaag
    15241 tgatttatta tgtagtggtc atagctttat tagtcagcgt atttctactg attgggatgg
    15301 acctaagctg gtttaatccc tatcaaagcg accaatttgt ttgggtctac tttgctctca
    15361 tcccagtaat tgaatggatt gaaaagaaat ccaaaaatct agcaagtgaa aaaggagaat
    15421 gaatatgaaa aagaaacgta gattgttatt tttgatgtct attgtcttgg ggggttcttg
    15481 ggcatgtttg tagggatgtt taaggcacgt gtcgaatccc acgaaattat tttagatgta
    15541 aaagccttga tgccatggat atcagctatt tgtttactga taggtttcat tagtatgttt
    15601 ttgactttca atttcttaaa gaaaagcaga aaatttcatt ccttgtatca agaggaaatg
    15661 gatgacgatc tgaatgaaac ctattatgtg caaatgtatc ggaatcttga gtttggaacc
    15721 attgctttta atattacagg tgtagcgatt ccattggcta tttttatttc attaagtgag
    15781 gtgattatat tgcatacaaa ccctcaaaca tttttccttt ctttcttact ctttgtggta
    15841 ttcttagtcg ctcaaaaatc tctttttaaa accattgcga ttgttcgtca gtttgatttg
    15901 gaatttttcg ctacaccaaa ggatgtcttg aactatataa attcttatga tgaaggggag
    15961 cgtcaggcta atttggaaca gagttttcga attttattcc aattacacca atatgtctta
    16021 ccagccttat atatttttct tattatcatt tctttcttga caggagagat tcagttacta
    16081 gctttcttgc ttgtaggagc catccatgtt tatatcaatg tgatgcagtt acctatggta
    16141 aaacgttatt tcaaataaag gagttatcta tgaaattact taaaaacctt ggctggattc
    16201 ttctagccct tctatccttt ttatttatct atggctttat tcaggggctc gcgactgcgt
    16261 cgcttgcttt aggcgcttca ccctatgctg ttactctact ctatgtggcc ttggctggag
    16321 tatatgtgta cggcatttac aaatggtatc agaaggctcc tgttcatatt gagaagagcg
    16381 gctttaatcg atttatttgg cttcctgtct tggtttggtt cttatctctg gtcgttcaat
    16441 tcttcttgcc agatgatcct tcagtaaatc agcaaatagc gacagacttg accttgtctc
    16501 aaccactttt ctcattcttt gctgtggtta tttttgctcc tttgacggaa gagattgttt
    16561 ttagagggat gttagcacgc tatctctttc ctaagcagga caatagtaaa cgaaccctga
    16621 tttttcttct ggtatctagt cttctatttg ccttgattca ttttccaggt gatgtgcaac
    16681 aattttttgt ctattttagc cttggtttta gtttgggttt ggcttacatt agcagaaaag
    16741 gtctggtcta cagtatttct cttcacgctt tgaataattt agtcggcttt ttgatgattc
    16801 tcatgctata atagagtcag gaggtcacat gaaacgagta attttattgg cagtgattca
    16861 ggcagtcgtt ctatttttca tcattggagc gctagcttat gccttcaaag gcgatttctt
    16921 ctataactat ctagcagttg tctttgctcc tattgcaggt gtactgcgtt ttgggacggc
    16981 ttacataacg gaaattgtct tgcctcgaaa ggcagccgaa atcgctgaaa agcgtaaagc
    17041 aggcaaaaat tcaaaataaa agagtccggt gaagttcatc ggatttttgt attatactca
    17101 atgaaaatca aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag
    17161 gttgtggatg aaactgacga agtcagctca aaacatggtt ttgagattgt agatgaaact
    17221 gacgaagtca gtaaccgtac tacggtaagg cgacgctgac gtggtttgaa gagattttcg
    17281 aagagtatta gcgctaattt ttagggcttt cacctgactt ttaaagactg gcaaactttt
    17341 ctgatgattt tcatgaagag cctgcgcttt tatggtaaaa tagtaacaga ataaaagagg
    17401 agagaaataa tgaaacgtag tatgtatgct ggtcgtgttc gtgaggaaca catcggacaa
    17461 gaaataacct tgaaaggatg ggttggccgt cgtcgtgacc ttggtggttt gatctttatc
    17521 gatcttcgtg accgtgaagg aatcatgcag ttggttatca accctgaaaa agtatctgca
    17581 gaggttatgg caacagctga aagccttcgt agcgaatttg ttattgaggt gactggtcag
    17641 gtcgctgcgc gtgagcaagc caatgataag ttgccaactg gtgcggttga gttaaacgtg
    17701 acagctctta ttgtgcttaa cacagctaag acaacaccat ttgagattaa ggatggcatt
    17761 gaggcaaatg acgatacacg tttgcgttac cgttaccttg accttcgtcg tccagaaatg
    17821 ttggaaaatc ttaaacttcg tgccaaggtg acccactcta tccgcaacta cttggatgag
    17881 ttggagttta tcgacgtgga gacaccattc ctttctaagt caacgcctga aggggcgcgt
    17941 gattatttag tgccgtctcg tgttaataag gggcattttt acgctcttcc tcaaagtcca
    18001 caaatcacga aacagctctt gatgaatgct ggttttgacc gttactacca aatcgttaaa
    18061 tgtttccgtg acgaggactt gcgtggagac cgccagcctg aatttactca ggtcgacttg
    18121 gaaacgtcct tccttactga gcaagaaatc caagatatta cagaaggctt gatcgcgcgc
    18181 gtgatgaagg aaacaaaagg catcgaagta acgctaccat tccctcgtat gaaatacgat
    18241 gatgctatgg ctctttacgg ttctgacaag ccagatactc gttttgacat gttgcttcag
    18301 gacttgacag aagtggtccg aggtgtagac tttaaagtct tttcagaagc acctgctgta
    18361 aaagcgattg tggtcacagg agctgcggac aactattcac gtaaagacat cgacaagatg
    18421 acggaagtag ccaaacagta tggtgccaaa ggtcttgctt gggtcaaggt ggttgatgga
    18481 gaattaaacg gaccagttgc caagttcttg actggtatcc aagaagaatt gacaacagcg
    18541 cttgttcttg aagataagga cttggttctc tttgtggcgg atacgcttga agtggctaat
    18601 gcaacactgg gtgcccttcg tggacgtatt gctaaagagc ttggcttgat tgataatgat
    18661 aagttcaact tcctttgggt ggttgactgg ccgatgtttg aatggtctga agaagaaggc
    18721 cgctacatga gcgcccacca tcctttcacc cttccacagg aagagactgc tcacgaatta
    18781 gaaggtgatt tggctaaggt tcgtgccatt gcttatgata tcgtcttgaa cggttatgag
    18841 cttggtggtg gtagccttcg tatcaaccaa aaagaccttc aagaacgcat gttcaaggct
    18901 cttggtttct caactgaaga agccaatgac cagtttggtt tccttcttga agccatggac
    18961 tatggtttcc caccacacgg tggtttggct atcgggcttg accgttttgt catgttgctt
    19021 gctggagaag aaaatatccg tgaagtcatt gcctttccta agaacaacaa ggcaactgac
    19081 ccaatgacac aagctccatc aacagtcgct ctcaaacaac tagaggaact cagcttacaa
    19141 gtagaagaag atgaaacaag caaaacgaat taagcggtgg cgctattatc tgcgccgctt
    19201 tgcttatcag ataaaaattt tacgtgtctt acaaagtatc tctcgagaaa agtatgatga
    19261 gaagatttcg gcctctctgg tctatggttt tttatcagca gtagcagtta atttcttttt
    19321 ccaaccaggg catgtgtatt cgagtggtgc aacaggtctg gcacagatta tctctgcctt
    19381 gagtaatcac tggtttggtt ttcatattcc gatttcgcta agcttctacg ccattaactt
    19441 ccctttgatg gtcttagctt ggtatcagat tggccataag ttcaccgtct ttacctttat
    19501 cacggtatct atgagttcct tctttatcca gtttgtccct gtggcaacct tgacggagga
    19561 tcccattatc aattcccttt ttgggggtgt tgttatgggt ttggggattg gttttgctct
    19621 tcgaaacaat atctccagtg gtgggacgga tatcgtcagc ctgactattc gcaagaaaac
    19681 gggtaagaat gtcggtagta tttctttctt ggtaaatgga actatcatgc tgatagcagg
    19741 tttaaccttt ggttggaaat acgctcttta ttctatgatt accatctttg tctctagccg
    19801 tgtgacagac gcagtcttta ctaagcaaaa gcgtatgcag gccatgattg tgacaaatca
    19861 tccagagaag gtaattgaaa aaatccataa aaaattgcac cgcggagcaa ccatgatcca
    19921 cgatgcagaa ggaacctata atcacgagag aaaggcagtt ttaatcactg tcattacacg
    19981 tgcagagttt aatgaattta aacagattat gacacaagtg gatccaagct cctttgtctc
    20041 tgtctcggaa aatgttcata ttctaggaag atttgttgag atagataatt agtgattaat
    20101 actcttcgaa aatctcttca aaccacgtca gcttcacctt gccgtaggta tggttactga
    20161 cttcgtcagt ttcatctaca acctcaaaac catgttttga gctgacttcg tcagtttcat
    20221 ctacaacctc aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgcactttga
    20281 ttttcattga gtataaaaag atcttgggaa aagactcaat ttcagtagaa aaggaagtaa
    20341 atcttcccac attaaaacgc atagtatcaa gttttttcaa tacctgatag tatgcgtttt
    20401 tgcttttaac gactttttgc ccagtctctt atttttcgat aattttgtgg gcgatcaatt
    20461 gacggtaaca aatttgttta ttgtttttat tatcattaat aatctggaga atagtttcaa
    20521 gggaaacacg accaagctct aaactattga tatcgacata ggctgccaag ttgagcttgg
    20581 gattaaccga gtcaaagctg agaacaggga catccagctg gtgtttggca atatagttac
    20641 aaacaccttc agctaggagg ctatcggttg tgatgatagc atcaatttgt ggatcgtgct
    20701 tgaataatcg cttgctaaat ttatagccct tttcttccag aaactcgtcg gcaaagtaga
    20761 tgcgattgtt gtcagtggta agtttgtaat gtttaagcgc ctgttcatag cctgttaaac
    20821 ggtctttggt cacgaagagc tttttacttc ctccgataaa ggcaatgcgt ttgcagcctt
    20881 ttttgatgaa atattcagtc gcatcaaaac cagcttgaac attgccgttg tcgacaagtg
    20941 ggatgaaagg agatagagat ttacctaaga taaggaaggg gaactgttct tctgcgacga
    21001 gttttacgag agggtcttct tcttgggcat agagaaagat tagcccatct acacgcttgc
    21061 cgtagaccat ttgtgaaata gcgttgagac gctccttctc atctttccct gttgctatct
    21121 gaatggcata gtggttttca gatgcgactt gagagatgcc acgtagaacc gatggaaaga
    21181 aaggattctg gtagaaggcg tctgagtcat caggaagaac taatccgata acctgagtat
    21241 agctgcttac caagctacga gcgttgaggt ttgggtggta gttgagttcc ttcatagctt
    21301 tgcgaacgcg tttttttgtt tcgtcgctaa tggttgattt attttgaata acacgggtta
    21361 cggttgaagg cgaaacacca gcagccttgg ccacgtcttt aatcgtaacg ggcataaaaa
    21421 tctcctattt atggtaattt ggatcacgga aatgtgtttt ataaaagata gtgaccagat
    21481 acagaacaaa aagaatattt tgtacagtaa tcagggttgt catattttgg ccaaataatc
    21541 ccaaaataag tgtaatcaga gtcggcaatc ctaaacagtt caagataaag tgatagcact
    21601 ctttaaaggt tctaaatgaa aagaggcgtg atttcttagt gatataaagg agaagactag
    21661 ctcctagaga gacgataaag aaattcaaac caaagaggaa gctcgcaccg agaactagga
    21721 agaggctgat atagacacga ttttgttggt accagtcttt agaaattgct tgggtcaagc
    21781 tgtctttgct tttgaaactc tcagtctgaa tggctcggta agagatgcgg gtcagctcct
    21841 tgctttcctt gctgatgact agctcatttg tatcgaaatg cagttgcaag tccttaggta
    21901 attccttgat ttgacttgga ccaatcacaa cagaaggggt ttgactagct gttccagtat
    21961 aagttaatgt gccatcgaca attgtagcat gttcagagag atcctggaca acctcatttg
    22021 tcagaggttc atagacatta tcgataaaag tttctagcgg ataggtctcc tgggagctgt
    22081 tttggatagc aatgggtacc atagacaagc tgataaggaa gatactggta aagagaagtt
    22141 gaaaccagtt gagctcgaaa cgtttggaca ggggcttacg aaacccccaa atacttgaaa
    22201 aataggaaaa tggatatgga agcataggta tctttctaaa aggtgttttc tatatgagta
    22261 ttattatata gagaaatgcg ctttatttca agtctaggag aaaaattgct tgctacaagg
    22321 atattattta cagtgacaat tgctaataat caatgaaaat caaagtgcaa actagccaca
    22381 ggttgctcaa agcacaactt tgaggttgga gataaagctg acgtggtttg aagagatttt
    22441 cgaagagtat aaaatgaaaa agggtggcgg ggataaatta tcccttgtcg ccaccacttg
    22501 taagtcctga aacaaagttc ttttgtagga agaagaagag aatacagatt ggaagggcga
    22561 tgaggatagc acctgctgag aagtaggcaa tcttcaagtt tttcgcattg ttaacgaagg
    22621 tttggagacc tacggcaaca gtaaagtatt ctttctcacg aagcaagaaa ctagagagga
    22681 tgtagtcccc gaaaggtccc atgaaggccc agagagcttg tacggcaacc attgggcgaa
    22741 caagtggtag aacaatttgc cagaagcggc ggaagtgtcc tgcaccgtct agttttgcag
    22801 attcgtctaa agacattggc actgtatcga agtagccttt catgagccaa gcattcatcg
    22861 ggataccacc accaacgtag aggaagatga ggaaccagtt gtggttaagg gcgttcaaca
    22921 taagcgccat aacgaagaag gctgtcaaag cggccatagt tggcaccatt tggatgatca
    22981 agaagaagac caaactttgt ttacgagcca agaagttgta acggctgtaa gcataaccag
    23041 caagtacgat gatacttgtt tgaacagcca tggtaattaa ggcgataatc aaagtgttga
    23101 ggtaccaagt accgtacaag gtttcagtga agaggccttt aaagttatca aaattgaggt
    23161 cgatattagt atctagttta aaggctgaga cgttacctgc tttaaaggct gacataatgg
    23221 taatcaacag tggatagata attacaattg atagaccaat caggtaaagg taagtaaggc
    23281 tttgagtcag tctacgtttg agtttaattg agttattcat cttagacgtc ctccatatca
    23341 aatgcgtgta gtttcttgaa tgcgatcata gagattgaga tgacaatgat agagataatc
    23401 aaggtaacag ctgccgccat tgagtattga ggagatgtac ctgttgtcaa acggtagatc
    23461 catgagatca agatatcggt tgaaccagct ccacctccga cactaccagg tcctccacca
    23521 ttgaagaggt acatgataga gaagttgtta aagttgaagg tgtattggct aatcaaagta
    23581 ggtgccgcaa cagccaaaat cattgggaaa gtgatgttgc ggaatttttg ccaagcgttg
    23641 gcaccgtcaa tataagctgc ttcgtaaagg tcgttaggaa tagattgcaa gatacccaaa
    23701 gtcaaaacgt agatgtatgg gaatccgagc caaccttgca tcataatcaa ggcaatctta
    23761 gtccaagttg ggtctgtttt ccaaggaata agagctccat caaggaaagg aaggaattta
    23821 gccaagattg gcaatacttg agtgttgata gcaccgacac tatcgttaaa catgtttgag
    23881 aatgtcaaga tagtgatgaa ggctgggaca gcccaaggaa gaaggaaaat aacaccaaag
    23941 atacgttttc ctttgataaa tggttggttg gcaatgatag ctgtgaagat accaattacg
    24001 atttgtaaag tagaagctgc caaagcccaa atgatagtcc aagaaagaac agaaccaaag
    24061 gcagaacgga aggtactcaa gctccaaatg tttgtaaagt tggtcaaacc aacccagtcc
    24121 aacaacttgt ttggtggcaa gtgttggaag tcgtagttgg taaaggcgat catcaaggtt
    24181 acgataactg ggaagataat cgcgaaggtc atggcaacat aagatggaat gatcaagagg
    24241 taagggaagc cattttcata aatccctttg atcatgtctt tgagtgtgcg tggaactgga
    24301 attccattgt taatgcgttt tgcaatcgta tgtgcatctt tgatatttga gaaataaaag
    24361 agtacataaa cgattacaaa gattagatgg aaggcaccac gaatcagcat aaagagggaa
    24421 ttatcacgac ctggtttgtc accaagagtg atgaggttgc tcaattcagg ggttgcaagt
    24481 gctaggaagt aaaggacaaa tacgatggtt acaccaagga agataaaacc tttggctttt
    24541 tgtttattgt aaatctgtcc taacccagga atgatagaca gcagggctgc tttactaggt
    24601 tgttgctttt ccatattaac tcctttcata ggatactact tttttataag aaagctaaat
    24661 tatttgtgtc tctattgata aattcaaagg gggatttgat ttccaccccc cttgaacaaa
    24721 ttttttattc accaaatttt tgtttgattg tttctttgat caatgttaca gcatcgttag
    24781 cagctgtttt agcatctttt tgaccactta cagcatcaaa gagcatattt ttcgctggat
    24841 cccaaactgc agacatttga gagatgtttg gcagtggttg agtgttcttg aactgtttga
    24901 taacagctgt tgtcaactca tcgtttttac cttcagcgta tgaacgagcc tcagtattag
    24961 ctgggatttc gttagtctta tcatataata ctttttgttg ttcagttgca acaaggaagt
    25021 ctacaaattt ttgagaagct tcaaggttct taacggcttg aggaatgacc caagctttac
    25081 caccaccgaa tgcagcatat tcttttccat ttggaagagt tgggatagtt gcaactccgt
    25141 agtttacttt agcatcttta aaggcttgag ctttccaagg tccgtcgatg atagcagctg
    25201 ttttaccttc ttggaattga gtttggatta agtttccagc accttctgta tcttgcatac
    25261 ctttaggcca tttttcgtac caagatttag cgtagttgat acctgcgata gaaccgtcgt
    25321 ttgcaagacc gatgtcttta gcgtctttac cgttttggcc aaagacgtaa gcaccgttac
    25381 cggcaagaag tccatatgta tagtagaagt ttgtccagtc agctaggaag gcagtagttt
    25441 taccatcttc accagcgaat gcgtatttgc tatctttagc aaggttttcc aagtcagcaa
    25501 atgtttttgg agcatctttc accaagtctt tgttgtagta cataacaagt gactcgataa
    25561 cggcaggagc accgtaaact ttaccattag cagctgttac aagagattta gttgtgtcgt
    25621 ctgttttagc accatcgctc aatttcactt ctgaaagttg tccgtcagaa ccaaggctac
    25681 ctacacggtc gtatggagcc atcataacat cagggacatt accagattgg ttgtcaagag
    25741 aaagtttatc aagacctcct agagcatcac cagttttaag agtgactttt actccagctt
    25801 ctttttcata agctttagca acctcttcaa tatagctctt atatccctcg tctacatata
    25861 cagtgagttc tttgacttca gatgaaccag aatcagcagg cttatcagca gttttgcttc
    25921 cgcaagctac caaaagcaag ctagcaagtg tagcagttcc aagcaccgca gtgctcttca
    25981 taaatttaga tgacatagtg tattcctccc aaagaatagc aagttttatt gataaggaaa
    26041 cgcaaacgtt ttcctttatg agcttagtat agcacaaata gaaaacggtt gcaagtattt
    26101 tttgtaaaaa ttttaaaaaa tttttaagct tgatttgata gcataatttt gcattttata
    26161 tagaagaaaa gtatgaaata gataagaata cagtattttt aataaaaata tatggaatct
    26221 gtctaaagag ggaaatcagg aggggctacc tccctgtttc taatccctat ctattttcta
    26281 tagacgtttg tgctttgttg catataaatt caagctccct aaggaggttt tgtactttgt
    26341 agactgtctc gtgagagtca aactttagga ttagatagtt ttaagttatc tttgctaaaa
    26401 tgagttagtc tccttaaaaa taatcaaaaa agttttttaa aaacgcttgc aattatgctt
    26461 gaaaaggagt atacttataa gtaacgcaaa cgtttgcgtc tgcaaaatac gcaacgttcc
    26521 attattttaa cacacgaggt gctattatga aaaaacgtca aagtggtgtg ttgatgcaca
    26581 tctcttctct tccaggagct tacggaatcg gatcatttgg tcaaagtgct tacgacttcg
    26641 ttgatttctt ggtccgtaca aaacaacgtt actggcaaat ccttccatta ggagcaacta
    26701 gttacgggga ttctccttac caatctttct cagccttcgc aggaaacact cattttatcg
    26761 atttagatat cttggtggag caaggtttgt tgggagcgag tgaccttgaa ggagttgact
    26821 ttggtagcga tgcgtctgaa gttgactatg ctaaaatcta ctatgcacgt cgtcctcttt
    26881 tagaaaaagc ggtgaaacgt ttctttgaag tcggagatgt taaagatttt gagaaatttg
    26941 ctcaagacaa ccaatcatgg cttgagctct ttgctgagta tatggctatc aaagagcatt
    27001 ttgacaatct tgcttggact gaatggccag atgcagatgc tcgtgctcgt aaagcttcag
    27061 cacttgaaag ctatcgtgag caattggcag acaagttggt ttaccaccgt gtgactcaat
    27121 acttcttctt ccaacaatgg ttgaaattga aagcttacgc taacgacaac cacattgaaa
    27181 tcgttgggga catgccaatc tacgtagcgg aagattcaag tgatatgtgg gcaaatccac
    27241 atctcttcaa aacagatgtc aatggtaagg ctacttgtat cgcaggatgc ccaccagatg
    27301 agttttctgt aactggtcag ctttggggta acccaatcta tgactgggaa gcaatggaca
    27361 aagacggcta caaatggtgg attgaacgct tgcgtgaaag cttcaaaatc tacgatatcg
    27421 ttcgtatcga ccacttccgt ggcttcgaat cttattggga aatccctgct ggttccgata
    27481 cagcagcacc tggtgagtgg gtgaaaggtc caggctacaa gctttttgca gccgttaagg
    27541 aagaacttgg tgagctaaac atcatcgcag aagaccttgg cttcatgaca gatgaagtga
    27601 tcgaattacg tgaacgtact ggcttcccag gaatgaagat tcttcaattt gccttcaacc
    27661 cagaagacga aagcattgat agcccacact tggcacctgc taactcagtt atgtacacag
    27721 gaacacacga taacaatacg gttcttggtt ggtaccgtaa tgagattgat gatgcgactc
    27781 gtgagtacat ggctcgttac acgaaccgta aagaatacga aacagtggta cacgctatgc
    27841 ttcgtacagt attttcatca gttagcttta tggcaattgc aactatgcaa gatttactag
    27901 aattggatga ggcagctcgt atgaacttcc catctaccct tggtggaaac tggtcttggc
    27961 gtatgactga agatcaattg acaccagctg tcgaggaagg tttgcttgac ttgacaacaa
    28021 tttatcgccg aattaatgaa aatttggtag atttaaagaa ataagacaat aatcaggaga
    28081 caactaaaca tgttatcact acaagaattt gtacaaaatc gttacaataa aaccattgca
    28141 gaatgtagca atgaagagct ttaccttgct cttcttaact acagcaagct tgcaagcagc
    28201 caaaaaccag tcaacactgg taagaaaaaa gtttactaca tctcagctga gttcttgatt
    28261 ggtaaactct tgtcaaacaa cttgattaac cttggtcttt acgacgatgt taaaaaagaa
    28321 cttgcagctg caggtaaaga cttgatcgaa gttgaagaag ttgaattgga accatctctt
    28381 ggtaatggtg gtttgggacg tttggctgcc tgctttatcg actcaattgc tactcttggt
    28441 ttgaatggtg acggtgttgg tcttaactac cactttggtc ttttccaaca agttcttaaa
    28501 aacaaccaac aagaaacaat tccaaatgca tggttgacag agcaaaactg gttggttcgc
    28561 tcaagccgta gctaccaagt accatttgca gactttactt cgacatcaac tctttacgat
    28621 attgatgtta ctggttatga aacagcgact aaaaaccgct tgcgtttgtt tgacttggat
    28681 tcagttgatt cttctattat taaagatggt atcaactttg acaagacaga tatcgctcgc
    28741 aacttgactc tcttccttta cccagatgat agtgaccgtc aaggtgaatt gctccgtatc
    28801 tttcaacaat acttcatggt ttcaaacggt gcgcaattga tcatcgacga agcaatcgaa
    28861 aaaggaagca acttgcatga ccttgctgac tacgcagttg tccaaatcaa cgatactcac
    28921 ccatcaatgg tgattcctga attgattcgt cttttgactg cacgtggtat cgagcttgac
    28981 gaagcaatct caattgttcg tagcatgact gcctacacta accacacaat ccttgctgag
    29041 gcgcttgaaa aatggcctct tgaattcttg caagaagtgg ttcctcactt ggtaccaatc
    29101 atcgaagaat tggaccgtcg tgtgaaggca gagtacaaag atccagctgt tcaaatcatc
    29161 gatgagagcg gacgtgttca catggctcac atggatatcc actacggata cagtgttaac
    29221 ggggttgcag cacttcatac tgaaatcttg aaaaattctg agttgaaagc cttctacgac
    29281 ctttacccag aaaagttcaa caacaaaaca aacggtatca ctttccgtcg ttggcttatg
    29341 catgctaacc caagattgtc tcactacttg gatgagattc ttggagatgg ttggcaccat
    29401 gaagcagatg agcttgaaaa acttttgtct tatgaagaca aagcagctgt caaagaaaaa
    29461 ttggaaagca tcaaggctca caacaaacgt aaattggctc gtcacttgaa agaacaccaa
    29521 ggtgtggaaa tcaatccaaa ttctatcttt gatatccaaa tcaaacgtct tcacgagtac
    29581 aaacgccaac aaatgaacgc tttgtacgtg atccacaaat accttgacat caaagctggt
    29641 aacatccctg ctcgtccaat cacaatcttc tttggtggta aagcagctcc agcctacaca
    29701 atcgctcaag acattatcca tttaatcctt tgcatgtcag aagttattgc taacgatcca
    29761 gcagtagctc cacacttgca agtagttatg gttgaaaact acaacgttac tgcagcaagt
    29821 ttccttatcc cagcatgtga tatctcagaa caaatctcac ttgcttctaa agaagcttca
    29881 ggtactggta acatgaaatt catgttgaac ggagctttga cacttggtac tatggacgga
    29941 gctaacgtgg aaatcgctga gttggttggt gacgaaaaca tctacatctt tggtgaagat
    30001 tcagaaactg ttatcgacct ttacgcaaaa gcagcatata aatcaagcga attctacgct
    30061 cgtgaagcta tcaaaccatt ggttgacttc attgttagcg atgcagttct tgcagctgga
    30121 aacaaagagc gcttggaacg tctttacaat gaattgatca acaaagactg gttcatgact
    30181 cttcttgact tggaagacta catcaaagtc aaagagcaaa tgcttgctga ctacgaagac
    30241 cgtgacgcat ggttggataa agtcatcgtt aacatttcta aagcaggatt cttctcatct
    30301 gaccgtacaa tcgctcagta taacgaagac atctggcact tgaactaata ctcttcgaaa
    30361 atctcttcaa accacgtcag ctttatctgc aacctcaaag cggtgctttg agcaacctgc
    30421 ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaaa tttatactaa
    30481 tacattttgt aaaaaagcga gtttcgattg aaattcgctt ttttaaatgc tgtggatttg
    30541 ggtcaatctt gtctaaaaat agggaaatcc tagatacagt gaaggcttta aatgctggtt
    30601 tttactgtct tcagccttat attttttcgt agttggttac ctcatatctc ttgtattcgc
    30661 ttacataaag tattataata taattgtagg aaagaaggtg tttttatgat atacacactt
    30721 aaattggtgt tgtttattac ctttcttgta ataagcttgt tacctgataa gatttttgga
    30781 aaaaataaaa aaatttggaa aatagttttt gcaatattga cggcagtggc agcattgtca
    30841 tttatgtact aagttatttt aagaatgtag ggaaataaac cctacattct ttttagtttt
    30901 ttctgttttc taaattctat ttatccaagc gcttcaacat ttcttgcttc ttcgcttcaa
    30961 gttctgcacg cttttcttcg atttcggcat gttttttctc gagttcagaa caacttgcac
    31021 cattgctaaa ttcttttcgc catcaggaga tagggtgagt cgacgtgtct attactcacc
    31081 caaagcagtc ctacaaagca ggaattttct gttacttttt tggaaatagt aacgtttata
    31141 cagctttgac acttcgtatc aaagcgccaa acacactccg agggatttac agaaagcaga
    31201 aaaggaatga tctggtataa gatcattcct tttctctctt tttctttaag taattatata
    31261 caatgtacga cgaagtcgtc attgcaatgc tgatccacca cctaaaggga actttaaaca
    31321 acattgataa gataaagaat ataaacaacg aaaatacgtt atacccaatt aattttattg
    31381 tatatctcat gattaaaagt taatccttct gttgttagga atggcatcat ttttatccca
    31441 taattgtgct aaataagtcc ccggtgataa taaattcata gcgaattcta aagcaacatc
    31501 atttacaaac caactaccta gatatctaga aattgctgaa cgaatagcac tttttgctgc
    31561 atgttttcct tttactttaa ttagatttgc aaggcctgca gtagttcctc ctaatgctaa
    31621 agctattgca gtatctaata gagcacccat ttgattaact gtaatacctt gccaagctgc
    31681 tctaaatgga gagtatgtag gtgggattgt ataatcgcct tgtaattgtc ggttaattac
    31741 ttctttgatc cattgttgtg agacgtctgg atgaaaagat tggatttcgt ttgcaagtgt
    31801 attgatttgt tcttctgtta gagaagtgac aggttgaagt tccatatttg tttcaatttg
    31861 tgatacttgt tcagaagcgt atacagctga aacacttgga atcgctgata caattaacac
    31921 aattgacgtc aaaaaaaccg aaataaattt cattaatttg ttcatgaact tttctccttt
    31981 ttatttgtat ctgcttacat tttatcatat actgttatta tagtcaaaaa aatatgctat
    32041 tatgttaaaa aaatattttt caaaatataa atggacggat ttattttgga ttttatttgt
    32101 tattttgacc tgcctctata ttggtaacca tgatttgttt actctcaatc atcaagaatt
    32161 ctcttttcgt ggtagcgttt ggggtctggt actggcctta tatcacttac tattcattga
    32221 taagtttgtt atatcgaatc gaaaataaag attagagcta tgcttgactg gctactttta
    32281 ggattgattt tggaggaaga ttttgtctct attatttatt attttaaatt tatttatttt
    32341 gtataagatc tattctttga ggcgggaaaa atcgaaatac ttgatttata cggcctatat
    32401 catatttggg gtaaatgtag tatatggtat tcaatggtta ttaaaagaac tgatttcaac
    32461 tatttcccct taatgtgtat ggaaactata acaaaacgca taagattaag gtttgtgtac
    32521 ctgttcttat acgtttttgt catattgaag attttcggta agttttctac ttttgcgaag
    32581 tctagtttat actcaatgaa aattaaagag taaactagcc gtaggttgct caaagtacag
    32641 ctttgaggtt gcagataaaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga
    32701 tgaaactgac gaagtcagta accatacgta cggcaaggcg acgttgacgt ggtttgaaga
    32761 gtattagaat gctttcccaa ccaaaatctc tgcttcgatg gtaatctctg tcagttggct
    32821 ccagtcaatc ttgctctggt caacgtgaaa gaggagagga gtcatactga gtagggcttg
    32881 gagttgttct gctgtgatag tcttagtcag agaggcagtt tgactagata ggatggtaaa
    32941 gtgttcctgg aaatgctcct tgatatcttg gttagaatac tccttgtttg tcagctggtc
    33001 ctgtactctt tgacggattt ctttgaggtg attttcagtt gggataacct ttatcaagat
    33061 accatctttg gataaaacgc gacgaaattc tccatagttg gcaggtgaga agatatcaag
    33121 caggatatcc atgctagcgt cttttatagg aaggcgtgcc aagtcgccaa cgaaccaatt
    33181 gactgcccag ttgggttcac ttttagcagc gatttggact gaatctttgg agatgtcaaa
    33241 ggcatagaaa gttttttcag agtgactttc ttgtagtttg cgagaataga atccttcacc
    33301 acaaccgata tccaaaattg ttatggtagt ttttgagctt gcaagcaagt cagatacagc
    33361 atctaagata gcttggtaaa agccggcttc taggatttgt tgacggtttt gaaaattttc
    33421 cttgtcatag ttagcagatt gcttgatttg aggtgctaga ttgacatagc caaatttcgc
    33481 caagtcaaaa gaatgacggt tgcagcactt gaaattagtc tctaacagag tcagattttc
    33541 ttgacagata ggacaggcaa aggcagtcgc agaagcaaaa cgctgaagtt tgggcttgag
    33601 atttgtattc atagtttaag tgtatcaaaa gaggcaaatg aaagcaactt taggaataag
    33661 tagatgggag attcagtaga aataaaacta attctccaat ttatagaatg aaattgcttt
    33721 tatatctaaa ttgctatata ataatgataa ggaggaaata agtatgttaa aagaagtatt
    33781 aaccgttgca aaagttgcga aaaaatcttc attatttttg ggtggtgtcg catttggtac
    33841 ccttggtttg aaaatcttag caagtaagga agctaaaaaa ggttattcta aagctttggc
    33901 taaggcttac aagttgaaag acgagctaga tgcatctgtt tctgttgtga agcaacatgg
    33961 agacgatgtc ttgcaagatg ccaaatattt gtacgagcaa gagaaaaaag aagagcaatt
    34021 agatagcctt ataggtgaat aatatgtctt ttaaagtgct acatagagga taccaacata
    34081 tccgactatc atcttctttt tcacttacct tggatattca agactatctt cgttccttgg
    34141 cgagagatga aaaggggatt gagtctatcc agttttacat ggatcaacag cactttactc
    34201 tacgcataaa agaaggcttt tctgtattag ataatgcaga agccttttta aaaagaattg
    34261 ataaagggaa agtttctgag ttgatgactc ttcccattcg tagagaagag agtgcttatt
    34321 ctattgtttc aggtgcagcg gttaagcgtg tactttttcg tagttttgtg ccgtatccta
    34381 ttcgctatat atggacttgt tatcaggctt tgggttatat tagagaagcc tatcaaacac
    34441 tagcgcgtaa ggaactaacg atggaagtct tggactgttc ggctatttta ttgtctttgt
    34501 ttatgaacca atcaaagaca gctagcaata tcatgtttat gcttgatttg gggaatcatt
    34561 tagatcagtg gtccttgaaa aaaactgcaa cagatttaga acagagtctt cttgcaaaag
    34621 agagcgatgt attcctagta cagggcgata cggttgttag tatcaagagt tccgatgttc
    34681 aaataggaga tgtcttgatc ttatctcaag gaaatgaaat tctgtttgat ggacaagtag
    34741 tttcaggttt aggtatggtc aacgaaagtt ccttgacagg agagagtttt ccagttgaaa
    34801 aaagagagtc tgatttggtt tgtgcaaata cagtattaga aactggagag ttacgcattc
    34861 gtgtaacaga taatcagatg aacagccgta ttttacagct gattgagttg atgaagaaat
    34921 ctgaagaaaa caagaaaacg aaacaacgct atttcatcaa gatggcggat aaagtcgtca
    34981 aatataattt cttgggggct gggctgactt acctattgac aggttctttt tctaaggcta
    35041 tttctttcct attggtcgat ttctcctgcg ctttgaaaat ctctactcct gtagcttatt
    35101 tgacagttat caaggaaggg ttgaaccgtg aaatggtgat taaggatgga gatgttctgg
    35161 agaaatatct ggaagttgat actttcttgt ttgataagac aggaacaatc acaactagtt
    35221 atcctatagt tgaaaaggtg ttaccttttg gagactatag tgaggaagat attctcagaa
    35281 tcagtgcctg tcttgaggaa cacatttatc atcctattgc taatgccatc gtcaagcaag
    35341 ctgagataga gggaattgaa catgaggaaa tgcatgggaa actccaatat atcgcaagca
    35401 aggggatcaa atctcatata gatggccaat cagttcttat tgggaattat gtcttgatgc
    35461 aggatgagca gattcatatc agttcagaac aaaatgcttt aattgaagag tacaagagtc
    35521 actacaatct cttattcttg gcttatcaaa atgaattgat tggaatgttc tgcattcata
    35581 ctcctttgag aaaagaagca aaaacagcct tggataaact taaggcacag gggaaaaaat
    35641 tgattctggc aacaggagac accttgatta ggacagagga attagtcaaa gatttgccct
    35701 ttgatcaggt ctatacagac ttgaaacctg atgggaaatt tgagttagta gagaaactgc
    35761 agaaagcagg tcacactatt ttgatggtcg gagatggatt gaatgactca gcggctttaa
    35821 ctctatcaga tatcggtgtg gtgatgaatg agagtgcaga tatttctaag cagatgagtg
    35881 atatcttatt gttagataat cgtttggatt tcttccaaga gttggattcg ttatcatcat
    35941 ctttgcaaac actcatcaag aaaaatattc aggataccgt tgtcgtaaat agtagtttga
    36001 ttggctttgg cttatttaat tggttcagtc cttcaaatct ctctatctta cataatctaa
    36061 caaccttgcg cattgtcctg cgtagcctgt ctattaaaaa tagatagatg agagttatta
    36121 acagcaaaaa ggagttacct ttctcgaggt taactccttt gtttatagat aaatgttgaa
    36181 tagtttagta agtcaataca aagtattttt tcttcccacg acggataaca gtcagttcat
    36241 tttctaactt atcagcgtca ctcaagacat agtcaaggtc ttggatgcgg tcgccgttta
    36301 cgtagatggc tccgttttgg acgtcttcac gggcttggcg ttttgagtta actataccag
    36361 atgagacgag cagttccacg atattgttgt tttcgtctgc ctgtacttgg tagtttggca
    36421 caccacgaag tccttgtttg agctctttga cagaaaggtt tttgatgttt cctgcaaaga
    36481 gttgctcagt gatgttaagt gcttctttgt aggcttcttc tccgtgaaca agtgtaacaa
    36541 cttcacgagc caagactttt tgagccaagc gttcgtgtgg cgctgcttca aattgtttac
    36601 gaatatcttc aatctcatca agtgacaaga aagtaaagat tttcaagaag cgaacagcgt
    36661 cagcgtccat cacgttcatc cagaattggt acatttcgta tggagaagtc ttttcgggat
    36721 tgagccagac ggcatttcct tctgatttac caaatttttt accagttgca tctgtgatta
    36781 gtggaacagt gataacgtga ccagtcttgt ccgccttacg acgaagcaat tcggtaccag
    36841 ctgtcatatt tccccactgg tcagaaccac cgatttgaag agtgacatta tggtcttggt
    36901 taaggacgaa gaagtcgtac ccttgcatga tttggtaagc gaactcagtg taagaaattc
    36961 ctgtttcgat ccgtttttta acagattcct tactcatcat gtagttgacc gtgaagtatt
    37021 ttccaatgtc acggaggaag tcaatgaagc tgatgctgcc aaaccagtcg tagttgttga
    37081 ccatgacagc cttgttttcg ccattttcaa agtcaagaaa acgagaaagt tgtccttgga
    37141 tagacttgac ccagccatct actgtgtctt ttgtttggag actacgttca gcatctttga
    37201 aggacggatc tccgatgaga cctgtagcac cgccaacgag cgcataaggt ttgtgacctg
    37261 ctagttgcaa gcgacgactt gtcaagattg cgacaaggtg gcctaggtga aggctgtcag
    37321 cagttggatc gtagccagta taataagaaa cttgaccttc ttctagggct ttacgcaaag
    37381 cttcttcatc agtcgtttga aatatcaaac cacgatcttt tagctcatca aaaatgtgca
    37441 tgtgtctttt ctccttttta aaattattgt ttctacctat tgtatcacaa acttgggcaa
    37501 tagcctagca gaatagggaa gaaagtggct attttattga aaatttccct tttgtggtat
    37561 aatagataga gtgaggaaat ccatgcaaaa tcaattaaat gaattaaaac gaaaaatgct
    37621 ggaatttttc cagcaaaaac aaaaaaataa aaaatcagct agacctggca agaaaggttc
    37681 aagtaccaaa aaatctaaaa ccttagataa gtcagccatt ttcccagcta ttttactgag
    37741 tataaaagcc ttatttaact tactctttgt actcggtttt ctaggaggaa tgttgggagc
    37801 tgggattgct ttgggatacg gagtggcctt atttgacaag gttcgggtgc ctcagacaga
    37861 agaattggtg aatcaggtca aggacatctc ttctatttca gagattacct attcggacgg
    37921 gacggtgatt gcttccatag agagtgattt gttgcgcact tctatctcat ctgagcaaat
    37981 ttcggaaaat ctgaagaagg ctatcattgc gacagaagat gaacacttta aagaacataa
    38041 gggtgtagta cccaaggcgg tgattcgtgc gaccttgggg aaatttgtag gtttgggttc
    38101 ctctagtggg ggttcaacct tgacccagca actaattaaa cagcaggttg ttggggatgc
    38161 gccgaccttg gctcgtaagg cggcagagat tgtggatgct cttgccttgg aacgcgccat
    38221 gaataaagat gagattttaa cgacctatct caatgtggct ccctttggcc gaaataataa
    38281 gggacagaat attgcagggg ctcggcaagc agctgaggga attttcggtg tagatgccag
    38341 tcagttgact gttcctcaag cagcattttt agcaggactt ccacagagtc ccattactta
    38401 ctctccttat gaaaatactg gggagttgaa gagtgatgaa gacctagaaa ttggcttaag
    38461 acgggctaag gcagttcttt acagtatgta tcgtacaggt gcattaagca aagacgagta
    38521 ttctcagtac aaggattatg accttaaaca ggacttttta ccatcgggca cggttacagg
    38581 aatttcacga gactatttat actttacaac tttggcagaa gctcaagaac gtatgtatga
    38641 ctatctagct cagagagaca atgtctccgc taaggagttg aaaaatgagg caactcagaa
    38701 gttttatcga gatttggcag ccaaggaaat tgaaaatggt ggttataaga ttactactac
    38761 catagatcag aaaattcatt ctgccatgca aagtgcggtt gctgattatg gctatctttt
    38821 agacgatgga acaggtcgtg tagaagtagg gaatgtcttg atggacaacc aaacaggtgc
    38881 tattctaggc tttgtaggtg gtcgtaatta tcaagaaaat caaaataatc atgcctttga
    38941 taccaaacgt tcgccagctt ctactaccaa gcccttgctg gcctacggta ttgctattga
    39001 ccagggcttg atgggaagtg aaacgattct atctaactat ccaacaaact ttgctaatgg
    39061 caatccgatt atgtatgcta atagcaaggg aacaggaatg atgaccttgg gagaagctct
    39121 gaactattca tggaatatcc ctgcttactg gacctatcgt atgcttcgtg aaaagggtgt
    39181 tgatgtcaag ggttatatgg aaaagatggg ttacgagatt cctgagtacg gtattgagag
    39241 cttgccaatg ggtggtggta ttgaagtcac agttgcccag cataccaatg gctatcagac
    39301 cttagctaat aatggagttt atcatcagaa gcatgtgatt tcaaagattg aagcagcaga
    39361 tggtagagtg gtgtatgagt atcaggataa accggttcaa gtctattcaa aagctactgc
    39421 gacgattatg cagggattgc tacgagaagt tctatcctct cgtgtgacaa caaccttcaa
    39481 gtctaacctg acttctttaa atcctactct ggctaatgca gattggattg ggaagactgg
    39541 tacaaccaac caagacgaaa atatgtggct catgctttcg acacctagat taaccctagg
    39601 tggctggatt gggcatgatg ataatcattc attgtcacgt agagcaggtt attctaataa
    39661 ctctaattac atggctcatc tagtaaatgc gattcagcaa gcttccccaa gcatttgggg
    39721 aaacgagcgc tttgctttag atcctagtgt agtgaaatcg gaagtcttga aatcaacagg
    39781 tcaaaaacca gggaaggttt ctgttgaagg aaaagaggta gaggtcacag gttcgactgt
    39841 taccagctat tgggctaata agtcaggagc gccagcgaca agttatcgct ttgctattgg
    39901 cggaagtgat gcggattatc agaatgcttg gtctagtatt gtggggagtc taccaactcc
    39961 atccagctcc agcagttcaa gtagtagttc tagcgatagc agtaactcaa gtactacacg
    40021 accttcttct tcaagggcga gacgataatt ctctaaatga agtggccaat caatggattg
    40081 ccactttttt cctttcgtgt tacaataagg gtatgaatca gtatcagaaa aagattgtta
    40141 acggaaaaat ttattcgctc ctatccggct taatatgggg aatctgtgga attttaggag
    40201 agtacttctt tactcattat caggtgtctt cgggctggat tacctctatg cgtttgacac
    40261 tggcagggag tcttgtactc atttggtctg caatacaatt aaaatcgcaa gtgctagata
    40321 tttggcgaga caagaaaaat tacctgccct ttttagccta tgctattttg gggatttttt
    40381 cagtccagta ttttttctat ctctgtgtag aatactcaaa tgctacgaca gcaactattt
    40441 tacagtttat tagccctgtc tttatcctct tttacaatcg cttggtttat caaaaacgag
    40501 cgtcaaaaag cgctgttttc tatgttttgg ttgccatgct gggtgtttgc ttgatggcga
    40561 caaagggaga tctctctcag ttatccatga cgccgctagc tcttataaca ggtttgctga
    40621 gtgccatggg tgttatgttt aatgttatct tgccccaacc ttttgctaag cgttatggtt
    40681 ttgttcctac ggttgggtgg gggatgattt tggccggttt gtttagcaat gtcctctcgc
    40741 cggtttatca gctttccttt actcttgata tttggagtat cttgatttgc ctcattatcg
    40801 ctttctttgg aacggctttt gcttttttca tttccatgaa ggctgtgtcc ttggtttctc
    40861 ctttggtggt tgccgttatc agtgccagtg aacctctctc ttctgctctc ttgagtgttt
    40921 tgttcttagg attagtagtg gattggtccc tccttctagc tatagccttg attattttac
    40981 ccatgatatt tttgtctata gaagaagcga aagaaagtag ataaaaagtc ttttcttaat
    41041 tctaaaagtg tgctatacta gaatagtcaa taaaacacgg ggagatagtt gtgaagagtg
    41101 tttttaggtt gtatcggtag gggcttgctt ttaccgacag cacgttttat ctcacatccc
    41161 taaaaaatca tacctaaaaa cagacaaaaa ggtttcaaat ttgaggcctt ttttggtaga
    41221 ataggtatca ttataacgaa ccaggaggca cctatgactg ctacaaaaat gaacgctcaa
    41281 gaaattatcc aatttatcgc caatgctgaa aagaaaacca gtgtcaaagt aacctttgag
    41341 gggcaactcg caactgctgt gcctagctct gttgtcaaac taggaaatgt cctattcgga
    41401 gactggaagg acgtggctcc gcttcttgaa ggtttggtag aaaatcaaga ttatgttgtc
    41461 gagcaagatg ctcgtaattc tgcagttcct ttgctagata agcgtgctat caacgctcgt
    41521 atcgagccag gtgctattat ccgtgaccag gtggaaattg gtgacaatgc tgttatcatg
    41581 atgggatctg ttatcaatat cggtgctgaa atcggtgctg gaaccatgat tgacatgggt
    41641 gccatccttg gtggccgtgc catcgttgga aaaaatagcc acgttggtgc aggtgcagtt
    41701 ttggcaggtg tgattgagcc agctagtgct gaaccagtcc gtgtcggaga caatgttctt
    41761 atcggtgcta atgcagtggt tatcgaagga gtccaaatcg gtagtggttc agttgtcgct
    41821 gcaggagcta tcgttaccca agatgtccca gaaaacgtgg tagtagcagg tgttccagct
    41881 cgtatcatca aagaaattga tgcccaaacc caacaaaaaa cagcgctaga ggatgcgctt
    41941 cgtaccttgt aattgtaaaa gtaaaaaaga ggcggaaccc tttttccagc ctctttctgc
    42001 tatatcggag gacagataga tgttagattt gattcagact agacgagatt tacaccagat
    42061 accagagatt ggcttggagg agttcaagac tcaggcttat ttgctggatg tgattgagaa
    42121 attgactacg ggcaaggatt ttgttcaaat tcgtacttgg cggacaggga ttttggtcta
    42181 cctgcaggga agtcagccgg agcgaaccat tggttggcgg acagatattg atggcctgcc
    42241 tatcgtcgaa caaacaggtc taccttttgc ttctcaacac caaggtcgca tgcatgcctg
    42301 tggtcatgat tttcatatga ccattgcctt aggctgtctt gagcgcgccc ttgaggagca
    42361 acccaagaat aatctgctct ttctatttca gcctgctgaa gaaaatgaag ctggtggtat
    42421 gctcatgtat gaggacggtg cttttggaga ttggttgcca aaccaattct atggtctcca
    42481 tgttcgtcca gatttgaaag tcggccagat tgcgactaat actcatacac tctttgcagg
    42541 aacttgcgag gtgaagatcc gtttcaaagg caaaggtggc cacgcagctt ttcctcatga
    42601 agccaatgac gccttggtgg cggctagtta ctttgtgacc caagtgcagt cagttgttag
    42661 ccgcaatgtc aacccaatcg agggagcagt ggtgaccttc ggcatttttc aagctggaac
    42721 caccaacaat gtcatcacag acacagcttt tttacatgga actattcgtg ccttgacaca
    42781 ggacatgagt ctcttggtgc aaaagagggt aaaaacagtt gcagaagggg ttgcagctgc
    42841 ctttgatatg gaagtcgaag tggaactcaa acaaggtgga tacctacctg ttgagaacaa
    42901 tccagccttg gcgcgtgaac tgatggactt ctttgacgaa aaagacggaa tcgagttgat
    42961 tgatatcgaa cctgctatga caggcgagga ctttggttat ctcctttcaa aggttgatgg
    43021 cgtgatgttt tggctgggta tcgatagtcc ctacgctctt catcaccctc aaatgagtcc
    43081 taaggaagaa gtcttagcta ttggggtggc tgcggtgtct agtttcctga aaaagaaggc
    43141 agcagaatag agggcttgtc tatgaaatcg gaattacgca agcaagtctt gcatgaaatg
    43201 aaggctatat ctcaagagca aaaacaggct atagaccaag ctttaaccga gcggctttta
    43261 caccatccct tctaccaaga agccaaggtc atcgcaacct acctctcttt ttctcatgag
    43321 tttcaaacgc gggaactgat tgagcaggcg ctgaaggacg gcaagaaggt tttaataccc
    43381 aaaacttatc ccaaggggcg catggacttt gtggtctatg atccgcaaca gttggtaaaa
    43441 actgcctttg ccttactgga gccacaggga gatgtggaag tggtggatgc atctcagatt
    43501 gatttgattc atgttcctgg tctggctttt acgacgaaag gatatcggat aggatacggt
    43561 ggaggctatt atgaccgcta tttggaacat ttttctggtc gtactttgag tacgatatat
    43621 ccttgtcaaa ttcaggactt tatacctgaa aaccatgata ttcctgttca ggaggtatta
    43681 attgatgaag gaaatctttg atagacgtta ccctgtgacg agtttcttcc tcttagtgac
    43741 ggccttggta tttttactaa tgttggtcac tgcaggcgga aactttgaca gggcagatac
    43801 attatttcga tttggagcca tgtatgggcc agctattcgc ctctttcccg agcaggtttg
    43861 gcgtctcttg tctgccattt ttgttcatat tgggtgggaa catttcattg ttaatatgct
    43921 ttcactttat tatcttggaa ggcaggtaga ggagattttc ggctctaagc agttcttttt
    43981 tctctatctc ttatcaggaa tgatgggcaa tctctttgtt tttgtattta gtcctaaatc
    44041 cttagcagca ggcgcctcta cctctcttta tgggctattt gccgcgatta ttgttcttcg
    44101 ctatgcaact cgcaatcctt atatccaaca gctagggcaa tcctatctga cactttttgt
    44161 ggttaacatt attggaagtg ttctgattcc aggaatcagc ctagcaggcc atatcggtgg
    44221 tgcagttggt ggcgcatttc tagcagttat ctttccagtt agaggagaaa aacggatgta
    44281 taataccagc cagagattag gagcggtagt cttgttcgta ggactcgcca ttttgctttt
    44341 ctacaaggga atggggttgt gacaactaat atgtaaactt gaataagaaa aaagctactt
    44401 aaaaaatgag tagcttttaa tgtgttttgg aaccattcga aacaacacag ccctaaaata
    44461 gttattaacg ttgtctaaaa tctgtaatgc cccctccaaa gtttcctacg tgattgccgc
    44521 ttgtatcacg aacatctccg tttgaacggt taaaataaaa atctctttgc gatccatctg
    44581 caccagttac gtgcccaaga atatagccat catttcctcc gttgtctgta gcagctggtg
    44641 ctttatagtt actattgtct ccaccagttg aacctgaata agattggcta ttatcagctg
    44701 tgtatgtttg ttctggagca taatctgaat taccagaata tgaactaaaa gaactgcttg
    44761 atgcttgaga tgaactattt gaagattgag atgaagttga ttcttctttc ttcttatctt
    44821 ctttagcttt gtcagatgct ttttgttctt cttctttctt cagaacatca atttgttttt
    44881 ggaatttgtc tgcaatatct gtaagagatt ttacagtttc atccaatttt ttttgtttga
    44941 aagtttcatc aactttcttg ataaaatcaa tttgtttatt gatttctttt acattatttt
    45001 ctaaggttgc tttatcttta aatttgtcat ctgaatcttt aacatcataa gccaaacctt
    45061 tttgcaaatg aaaatctaca attgctttag atgattcttt gactttgtta ttaagatagt
    45121 ctttacctgc atcggtttta agtgaagttt cagatagttc ttttaattta gaaatagatt
    45181 catctgaaga tgcatcaaat gattcaaata gtttatcaac ttgttctttg tctgatttgc
    45241 tatctttttc taattgtaca atttttgctt gttgttctgc ttgttgttgg ttatatgaat
    45301 accatccaaa ccctaatacc aatacaacac caactgcaac tgatgaaatg attacttttt
    45361 tattgttttc gataaattct acaaatttgt tctccataat cttttacttt gatagtgtcc
    45421 gcaattactt taaaattaaa attacaccta tctttctccc ttattatatt tttattaata
    45481 gcttccacaa aattaaacaa cttatgttcg gctcggttga tttaatttaa ccatgactac
    45541 tccaacagtt aagtcaaatt taaaattatt tattattttg gaaccattcg aaacaacata
    45601 gcaaagttaa aataaggctt tgtccgtaca caacttgaaa aagtgcgcac cgattcggtg
    45661 cttttttgtt ttactatatt aatttattct actcttattt taatgaaaaa acaaatacaa
    45721 gtatagcgtt ttcattagtt tttattaaat aggtagattc aagtagagaa tttacttaat
    45781 ttatgtgtgg ctaatcttta tataaatgat tttgttattc cttctcagtc aattcttttc
    45841 caagttggat gaggtaattc ttcaaatcat ctttgacttg tgggtgtttg agggcgtagt
    45901 cgatggatgt tttcatgaag ccaaacttgt ctccgacatc gtaacgagcc cctttgaact
    45961 cacgagcaaa tacacgttgt gttttattga gggtgtcgat tgcatctgtc agctgaattt
    46021 catttcctgc acctggagct tgcttttcga gaatctcaaa aatttcaggc gtgaggaggt
    46081 agcgtccgat aatagcaagg tcgctaggag cgtcctctgg agctggtttt tcaacaaagg
    46141 tttcaacact gtaaagacca tcttttcctt cgccttgcgg agcaataacc ccgtaagcag
    46201 atacttcgtc atgagggact ggcatgacag cgatagtaga cgcgtgggta cgctcgtagt
    46261 catccatgag ttgtttggta agtggaacag ccttttcgtc tgtgatatcc atcaagtcat
    46321 caccaagcat aacgacaaaa ggttcatttc cgacgaaagc cttggcttgc aaaacagcat
    46381 ctccgagacc gcgtggatga gtttggcgga taaaatgcag acgcatgcca gttgtttcat
    46441 caactagctt caaaagatct gttttccctt tttctttgag gttatattcc aattcgaagt
    46501 ttgaatcaaa gtggtcctca atagaacgtt ttgatttacc agtgacaact agaatatctt
    46561 caatacctga tttgagagcc tcttccacga taaactggat agttggtttg tctacgattg
    46621 gcaacatttc tttggcaagg gccttggttg ctggtaaaaa tcgagttcct agtccagcag
    46681 cagggatgac tgcctttcta acttttgatg tcataaaaat cctttctata gagggttaag
    46741 accactcatt ttctgcttta aattcattgt tcatgatgtc ataaatggca tctttgatat
    46801 tggttccgtg ataaataact tggtaaatag cctgtgtaat gggcatatag actccaagtt
    46861 cttgggctag ttcataggct gctcgagtcg ttgaaattcc ttcgattacc atgcccatat
    46921 tagcttctat atcagctagg gattctcctc gtccgagagc atctccagct ctccagttac
    46981 gagagtggat ggaagttccc gttacgatca aatctcccac accagataag ccgctatagg
    47041 tcaatggact ggccccgagt gctaccccta ggcgggtgat ttctgctaaa cctcgagcga
    47101 tgatggctgc cttagcatta tcaccaaatc caagaccatg taaagctcca gcaccgacag
    47161 caataatatt tttaagagca ccagcagttt caaccccgat aacatccgta ttggtataaa
    47221 gtcggaagta gtgattacta aatagctcct gaacgtattg agctgtttgt aaatctttag
    47281 aagcagcagt gattaaagtt aggtcacgca caatggtttc ttccgcatga ctaggccctg
    47341 aaacaacgac aatatcactg cggagctgtt caggaatttc ttcttcaagg atagttgata
    47401 atcgtttatg gctatcaggt tctaatccct ttgaagcgtg catgatgata gccttatggt
    47461 ccaaggtttg tgcaacttgt tgggcaacaa gtcgtgtcac ttttgttggg acaacaaaca
    47521 aaatcgcatc cacatctttc aatgtttctg ctaagtcggt gtaggcaatg atattttcat
    47581 ctagaacgac atctttaaag tagtgcttgt tagtatgata ggtattaatt tcattgattt
    47641 gctcgggaag atttccccaa atacgtacct cgtgtccatt gtcatttaag acttgtgaaa
    47701 gggcagttcc ccaagaacca ggccccaaga cggcgacggt ttgtttttcc atgatttcct
    47761 ccttgataga gttctttcca ttattctatc atattctaga ggattttgca cttgcattac
    47821 tggggtatgg tggaaaaata cacaaagacc gagatgaagg gataaactct tagtctttag
    47881 ttaaagtgag aagaaatctg atagatagtt tgattcagta tatgcttata atagaggtaa
    47941 acaactcagg aggttcttgt aggttgcgag agtttggcga aaaaattaaa agattacgtt
    48001 tggctaaaaa aatcagtcgt tcagaatttt gtggtgatga gtctgaatta agtatccgtc
    48061 aattaattag aattgaaaat ggagaatcca gaccaacact aacaaagtta aaatatatcg
    48121 ctgaacgttt gggggttgag gattacaagt tgatgccaag ttatatagag ttggataagg
    48181 aatacctaga attgaagtat ttcttgatga ggactcctac atacgaagat gaaactatcg
    48241 cccaaaagaa agagagtgtt ttgataagat ttttgaagag tattatgata ggctacctga
    48301 ggaagaaaga tttatcatcc caaattattc atatctggca ctaacgaact acacagttca
    48361 aaaattacca gaaaagctag ttgaaatact gtccttctgg tgattttgct taatttctga
    48421 tgttagagac ataattgagg agatttgtct tgattttttc ctaaaaaagg gcagactcct
    48481 cccttggttt gatgctcgat ttttaaaata aggtgactta ttctgttagg catgttttcc
    48541 cctgccctct agctctatat ggaacaggga gtatcagatt tatctggcag attgtatcaa
    48601 ataaggcttg aaactgtttt gaataggcat atagacttga gaatttgaga atatgtcgtc
    48661 tagcagtaga gacatatttt ccggcaatat gaaggaagag acgtcgaaaa cgcttgatag
    48721 tcaaggcctt tacttcatca ccagctagct gctttaaaaa gaggtagaga ttataagcca
    48781 gacagcccat catcatacgt acttcattct taatcatggt cgaactatct gtcttatccc
    48841 caaagaatcc tgctttcctt tctttgataa agttttcagc attccctcgt tcacgataga
    48901 attgaaacag ctcctcacta tctacactgc ttaaattggt caaatgaact tttttacaac
    48961 cataaaaaag agcacttaat cgtactcttc tcttttaagg attagttgaa ttaattcaaa
    49021 tccactagtt ctcctgtttc taggtagact aggcgttcac aaatgttagc aatgtaatca
    49081 gcgaagcgtt ccagatgccc tatgatataa aggtattgtg ttccattggg aattgaggtt
    49141 tcttggtctt tcataagtcc aatgatttcc tttgataagg cataataata ttggtcaatc
    49201 tgttcatctt tttgagcaat actaatagct tttgaggctt ggtgcaaagg aaaggcaacc
    49261 aataaatcgg atagcatgct gagggataat ttacccattt ggtgtaactg ttcttcgtca
    49321 ggggctagtt gattttcttt tagttgcaaa acagctttag caatgcctgc catatggtct
    49381 cccatacgtt caaggtctga acaagaagac atgatgctaa tcacaaatcg aaggtcagac
    49441 acttgtggct gctgcaaggc caacaaacgg gcacaggtca attcgatagc gctttgacct
    49501 tggttgatag catgatcctt attgataatt agctctgcca tctccttgtc tttggaggct
    49561 aaggccagta aggcttttga agctgtttca aggacaagtt gccctagtcc taaaaaggat
    49621 tgttctaatt catgcaattc taagtcaaat tgatttctca taggtttttc cttccttatc
    49681 cgaaccgtcc tgaaatatag tcttctgtgc gctgatcttt tggattggta aacacgtcaa
    49741 cggtatctcc aaattcgcaa atttctcctg ttaagaaaaa agcagtttta tctgaaatac
    49801 gtgaagcttg ttgcatgtta tgggtaacaa tgataatcgt ataatccttt tttagttgct
    49861 gaatgaggtc ttcaattttt aaagtggaga tagggtctaa ggctgaagtc ggctcatcca
    49921 ttaacagaat atcaggttct actgctaaag ctcgcgcaat gcaaaggcgt tgctgctgac
    49981 cgccagataa ggacatggca ctctttttaa gatcatcttt gacttcttcc caaatggctg
    50041 ccccttttaa agatttctcc actaaggcat ctaattgttt tttgtctcga ataccatgtg
    50101 tccttggacc ataagccacg ttatcataga tagacatggc aaagggatta ggctgttgaa
    50161 aaaccatccc tacacgctta cgtagctgat taaggttgaa tttgctacta taaatatctt
    50221 gctcatctaa gaggacttgg ccttcaatat ggcaagaagg aaccaaatcg ttcatccggt
    50281 taagggtttt tagaaaagtt gatttaccac aaccagatgg gcctatcaag gcagtaatct
    50341 gtctttctgg taattgaatc gaaatatttt ttaaggcttg aaaatccccg taaaataagt
    50401 ctaggtgtct gactgaaaat gttcccatac taggaagctc ctttcacaag ttttcgagat
    50461 aataagcttg atagagtatt tatcattaaa acagtaataa tcaaaatcac accggtagca
    50521 taggcttcat tgacatgtag cccctcactt gacagcatat acatatgcag ggctagagaa
    50581 cgacctgaag acatgagact acttggcgta ttggtagagg tacctaatgt atacatgagg
    50641 gcagctgtct caccaacgat acggccaata gctagtatca ctccagctaa aatacctggc
    50701 atggcaactg gtagaacaat tctaaaaaca gtccgtaact tacctgcccc aagtccataa
    50761 cttgcttgac gcatgctatc actaacagat aaaagggctt cttctgttga gcgaataatg
    50821 actggcaaca ccatgatgac tgaggttaag attcctgata acagagagta ttgaaaacct
    50881 aagaagacta caaagaagag catgccaaac agaccaaaaa caatggaagg aatcccagac
    50941 aaggtatctg aggccaatcg catgatttta acacaaaggg aatctttttt tgtatattcc
    51001 acaagataaa aaccagcaaa aatccctatg ggcaaggcta aaagaagagc accaaagacc
    51061 agaataacgg tggaaataat cgctggcata agggaaatgt tctcagaagt ataagtccaa
    51121 gaaaagaggg atagacttag atgaggtaag cctttgatga ggataaaacc aatgattaaa
    51181 aagagagagc caaaggttaa agctgaaaaa caataaacga gaagttttag caggtattta
    51241 ctcataagat gattttcctt tcaagtaggc aaagtaggca ttaatcaaga gaataaggaa
    51301 aaagagaact gctgaggttg caataagggc ttccctatgc tgacctgatg cgtaagccat
    51361 ttccagaaca atattggttg ttaaggttct ggttcctgaa aagagtccac ttggaataat
    51421 cggctggttg cctgccacca aaataactgc catggtttca cctactgcgc gaccgattcc
    51481 taaaataact gctgataaaa taccagatct cgcagctggc aagatgacac taaaaatact
    51541 ccgttcatga ctagctccta gagccaagct accagaataa tacgttttgg gaactgttcg
    51601 gatagcagat tctgacaaac tgataatggt tggcaaaatc attattccta atagtaacga
    51661 agcggttagg acactcatgc catttcctaa aaagcttcta atccaaggca ccaataattg
    51721 taggccgaaa aaaccataaa caatagatgg aatggccgcc atcaagttga tagctgattt
    51781 taagaagcca tagatgggct ttggacaata ataaaccata aacaccgatg tcaagatgcc
    51841 tgttggcacc ccaatcacaa tcgctcctaa ggtaattaat aaggaaccaa cgatcattgg
    51901 taaaatacca tagcttgccg gaatgttcgt tggcgaccaa tcactgccta ataaaaaacg
    51961 ggcaaagccg tagttagcca tgaaaggtaa gccattacta aaaataaaga aacagattag
    52021 caaaatagct acaacagcta ctgttgcact catgaaaaaa attgccctaa aaactgcttc
    52081 tttgaaggct tgttttatca catcttgtcc tttctagtga agaaagtaag ggagatacga
    52141 cacctcccta cttgccttct ttatcttatt gtacgatgaa acgtctgcat ctctttagag
    52201 atttatggag caaacatttt atttaatctt gtcccaggtg gttaatttgc cactaaaaac
    52261 gtctgcaagt tcagccatac tgacttggct tgccttattg tcattattga ccacaacagc
    52321 aataccgtct aaagcaatag catcatgggt gagactctta ccttcttcag gagttaattc
    52381 cctagaaacc ataccaatat cagcggtttt ctccttaaca gcggtaatac ctgctgaaga
    52441 cccattagag gtaatatcaa tcgtaacttc tggattttct tttttataag cttctgctaa
    52501 tttttccatt aaagaagata ctgaagtgga acctacaaca gacaacttgc ctgataagtg
    52561 ttggcttgta tattctgtgg tttcggtttt agcttcaata aatttattat ctgtgaccac
    52621 ttgttgacct tgtttggagt ggataaagct gataaaatct tgacctagct tggaaagatt
    52681 agaggaccaa acaatgttga agggacgttg aagagggtat tcaccatcta aaactgtgtc
    52741 tcgactagcc ttgacaccat caatctctaa agccttgaca gatttcgtta aagatcccaa
    52801 ggagatgtag ccgatagcat tagcattccc ttgaactgct gagagaacac cttctgtact
    52861 attttgaatc acagctgttt tggcagtgtt gtcaattttt ttatcaccgt cttttttgag
    52921 aatccctgtg atttctgtga aggcaccccg tgttccagag ccattttctc gtgaaatcac
    52981 ctcaatcgtt cctgaagctg actgtttgga agcagctgac tgattgccac aggcaacaag
    53041 cccaaatcct gataagccaa tggctgcaag agtaagcatt tttttgaatt tcataataat
    53101 cacctttatc tctatgtatt tttcttgtgt aggcttacta catttatagt ctaacaagtc
    53161 tttgtaaagg tttatccctg attcatgtaa agattgtgta aagaatcaaa aaaagccact
    53221 tttgaaaaat ggctgctcct aaaaatagct ttaaaaatta ttagtcctgt gcgaaagatt
    53281 ggttaggaag aaaaatcgtg aagcaactgc ctctgccaag ctgactcgtc accgtgactt
    53341 ggccacctaa taattgactg agttctttga caatggcaag gccaagacca gtgccaccag
    53401 tttgtctgct tcgaccttta ttaactcggt aaaaacgttc aaaaatacga tcctgctcta
    53461 attgactaat accaatccct gtatctgata cagaaatctt aatgccttcg ttcacctttt
    53521 gggtcttgac ctcaattttc cccccttgtt cagtgtaacg gatggcattg gataaaagat
    53581 tgagtaagat ttgggaaagt aattgactat ctgatacgag ggtgacatca tctggcacct
    53641 gcacctttag ctgtaaatcc ttcttcttga gctgaggttg caagctttga gtcaaatcct
    53701 gtacaaattc tgccaaagaa agggtcgtcc attgtatagg catttgttga gccttagata
    53761 aggtaagaag atgctcaaca atatgctcaa gacgcaaact ttctttgtaa ataatgtcta
    53821 gaaagtcatc cttgagcgct tcttcttcag ctgacatccc cttaatggtt tcagcaaagc
    53881 ccttaatcga agtaactggt gtcctcaatt catgggaggc atttgagaca aaggctaaat
    53941 ttaacttttc ataagttcta atcgttgtta aatcatatag caagacgagc acagcttcca
    54001 cagattgggt ggggctaaaa acgggaactg ctgtcacttc taaaatcaag tcaccctcat
    54061 gaaacccact tacttcttgt tttaaccttg ttttttgatc aaaggcttgg tgaactaaat
    54121 ttcgaatatc catccgtttg aggtcatcaa gtgaacttat gtcgccgtcc acatcgggaa
    54181 aataatgagg cagagagcga ctggataata acatctgacc ttgagcggaa actaaaaacg
    54241 tccccatggt taggtgcgac agaagaacct ccattgtttc ggctaggtcc ttgtattgct
    54301 gatcctgttg ggagactttg gtttttaggg cagacacata ctgagccaaa gactttaagt
    54361 cttcttgccc tttttctaaa aagtattcac tactggtcaa gagaggttgg tgcaaggtct
    54421 caaaagcaac ttcccatttc caaaggcaaa agagccagta gccaccttgt cccaaagaaa
    54481 gtgctagaag aaagagaccg atgcctttac tgatccaagt taatgccatc cctgcaatca
    54541 gaatgaggct aacacttaga ttgactagcc aaaattgaag gtagcgtttc atctataact
    54601 ccttgaactt ataaccataa ccccgaatgg ttcgaataaa ttgaggggtt ttaggattgt
    54661 cttcaatttt ttccctcaac ttaccaatat gaacgtccac caaacgtgtt tcctgcccaa
    54721 agtcataccc ccagatacgt tccaaaagac gctctctagt cagtgtcatg ttgggatgtt
    54781 tcataagata gagcaagagt tcaaattctt ttggggtcaa actcagtaac ttattcgcct
    54841 tgtagacttc atgacgctca gggtatactt tcaaggtccc aaatagccaa gaatcgtcag
    54901 cgatattatc tgaatcatct ccttcttgtt ctcctttagt tcgcctgagg acagccttga
    54961 cacgcgccag caattctcta gggctaaaag gcttggtcag gtagtcatca gcccctaatt
    55021 ccaaggccaa aaccttatca aattcatcac ttttcgcaga aaccatcata attggagttt
    55081 tgacgccttt ggctctcagc cgcttacaaa cttccatgcc atctaattgt ggtaacatga
    55141 tatcaagcaa gataaaatca aagggttctg tttctgccaa agctaaggcc ttccgtccat
    55201 ttgttaccaa ttgagtagaa aagccttcct tacttaaatg gtagtcaagc aatttcagaa
    55261 tgtgttcttc atcatccact aataagactt gttttgtcat ctattatctc ctattggtaa
    55321 cattataaca caattatcag aaatcctaac attgctaaat cagattaaat ttgcttatca
    55381 agactagtat ctggtcaaac gctcaatcat ctccttgtgc tctggatagg tcgccagtag
    55441 atctaccctt tcaaataatt caaaatcctc aaattcaaaa ccaggagcaa caagacaaga
    55501 aaccagagca tcatccttat caactgttga ttcccaaata gtgcccttag gaacacagta
    55561 gtgaagttgt tgccctttgg atatgtccag gcctaaagtg actgcttcgt agtgaccatc
    55621 tgctgtaatc atgtgaacag taagtgggga tcctgcatga aaataccaga tttcatctgc
    55681 tgtcaatcgg tgaaaatgtg aaggattcgt ttcttctaat aagaaataaa tactggtata
    55741 aagcgccctt cccttaccag caaggtttat agtgtctgaa gctttttttg tttgtctaaa
    55801 atagccacct ttaacatggg gagctaactc tagagttctt atcaagtctt ctttatccgt
    55861 cggagccaat gggttgaagt aactcttgtt caaagtggtt ttacgatttc aagaactcct
    55921 ctcagttctg aggacacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa
    55981 aaaacaatta gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat
    56041 tgtcacaagt caaggaagaa ttatttcttt ggatatcact gtgaactatt gtcatgatat
    56101 gaagttgttc aaaatgagtc gcggaaatat cggacaagct ggtaaaatct tggctgacag
    56161 tggttatcaa gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa
    56221 actcaagcca ctaacagttg aagataaagc ctataaccat gcgctatcca aggagagaag
    56281 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgatttcaa caacctatcg
    56341 aaatcatcgt aaacacttcg gattacgaat gaatttgatt gctggcatta tcaatcatga
    56401 actaggattc tagttttgca ggaagtctat tatttggtta ggtgaattag tgaagcgttt
    56461 aggcaagtgt ctctggttac gacgtcatgg cctctaaatc gattatattt aggggtcatg
    56521 actagtgaag cagttagcta gttcgcatat aagcggctag cgtctaacaa ttaggaactt
    56581 tagttccaat aactttaaga ttacgacgtt ttaggacata aatcgatcat atttatgtcc
    56641 taaaactagt gaagcgccta gccaaagtcc gaataggatt tggcgttagt tacttagatt
    56701 gctttgcaat caagtaactt tggcgattta catcttctct ggcgcttcta ctccaagcaa
    56761 gcgaagggct tctttgagaa cgactgcggt tgcgtagctg agggctagac ggctgtcgcg
    56821 ttctgggctt tcatccaaga tacgtgtatg tgcatagtat ttgttaaagg attgagccag
    56881 gctaattgca aatttagcaa tgatagaagg ttcaaagtta tctgccgcac ggttgataat
    56941 acgtgggaag tcttgaatga gtttaatgat ttcccagctt tcagtatcat tcaagctata
    57001 gttgccagct gtttctggtt tgaaatcggc tttgcgtaag atagattgga tacgagcgta
    57061 ggcatattga acgtaaggtc cagtttcacc ctcgaaggat accatagcct ctaggtcgaa
    57121 gtcgtatcca tttgtacggt cggttttgag gtcatagaat ttaatggctc caaccccaac
    57181 agcatgtgct acctgatctt tattttccaa ttcaggattt ttagcctcga tttggacctt
    57241 ggcacggcta acagcctctg caacagtagg ctctagcaag atgacattcc ctttacgagt
    57301 agagagcttc ttcccttctt ttgtaaccaa gccaaaagga acgtgagtaa tgtcgtcact
    57361 ccagtcgtag cccatctctt gcaagacagc tttgagctgt ttaaagtggg cagattgttc
    57421 ttgaccaacg acatagatag atttagcaaa ttggtattcg tttttacggt aaagggctgc
    57481 agccaagtca cgtgtgatat agagagttgc accatcagac ttcttgatga gggctggatg
    57541 ttcaattccg tatttctcaa gattcacaac ttgggcacct tctgattcaa gaagtagtcc
    57601 tttttcagaa agaatgtcta caactgcatc catcttatca ttgtagaagg cttctccgtt
    57661 atagctgtca aattcaacct tcaattcatt gtaaaggcgg ttaaattcca ctaaactttc
    57721 atcgcggaac cattgccaaa gagcgagagc ttcctcatct tcattttcaa gtttacggaa
    57781 ccattcgcgc gcttcttcat ccaagctagg gtcattttca gcttcagcgt tgatgcggac
    57841 atagagttta aggagttcat cgattggatg agcttttaca gcttcttcgt cgccccattt
    57901 tttgtaggca acaatcaaca tcccaaattg tttaccccag tctcccaaat ggttgacctt
    57961 gaccgtttga taaccgattt tttggaaaat atgtgacaag ctatctccga taacagttga
    58021 acgcaggtgg ccaatagaaa atggtttagc gatattcgga ctagacatgt cgataacaac
    58081 attttcttgt ttgccaatat tttggtcagc atagtgttct ttttcagtgg taacagcttg
    58141 caatacttga gcagaaatgg cagatttatc aaggaaaaag ttaacgtaag gtcctgttgc
    58201 gacaactttt tcaaaggctt gggtgttcat tttttcagcc agttcagccg caatcatttg
    58261 tggtgcttta cgttcgactt tggcaagaga aaaagcaggg aaagcgatgt cacccatttc
    58321 tgagttttta ggggtttcca gtaactttaa aatagcctct tggtccaggc tatcaatgat
    58381 gctagccaat tcgctagcaa tcaattcttt tgtattcatt aagagctcct ttttggactt
    58441 ttctactatt ttatcacaat tttaaagaaa gaagaaaaaa tttttgaaat ctcctgtttt
    58501 tttggtataa tatggttata aatatagtta taaatataca cgcaagagga ttttatgaga
    58561 aaaagagatc gtcatcagtt aataaaaaaa atgattactg aggagaaatt aagtacacaa
    58621 aaagaaattc aagatcggtt ggaggcgcac aatgtttgtg tgacgcagac aaccttgtct
    58681 cgtgatttgc gcgaaatcgg cttgaccaag gtcaagaaaa atgatatggt gtattatgta
    58741 ctagtaaatg agacagaaaa gattgatttg gtggaatttt tgtctcatca tttagaaggt
    58801 gttgcaagag cagagtttac cttggtgctt cataccaaat tgggagaagc ctctgttttg
    58861 gcaaatattg tagatgtaaa caaggatgaa tggattttag gaacagttgc tggtgccaat
    58921 accttattgg ttatttgtcg agatcagcac gttgccaaac tcatggaaga tcgtttgcta
    58981 gatttgatga aagataagta aggtcttggg agttgctctc aagacttatt tttgaaaagg
    59041 agagacagaa aatggcgata gaaaagctat cacccggcat gcaacagtat gtggatatta
    59101 aaaagcaata tccagatgct tttttgctct ttcggatggg tgatttttat gaattatttt
    59161 atgaggatgc ggtcaatgct gcgcagattc tggaaatttc cttaacgagt cgcaacaaga
    59221 atgccgacaa tccgatccct atggcgggtg ttccctatca ttctgcccaa cagtatatcg
    59281 atgtcttgat tgagcagggt tataaggtgg ctatcgcaga gcagatggaa gatcctaaac
    59341 aagcagttgg ggttgttaaa cgagaggttg ttcaggtcat tacgccaggg acagtggtcg
    59401 atagcagtaa gccggacagt cagaataatt ttttggtttc catagaccgc gaaggcaatc
    59461 aatttggcct agcttatatg gatttggtga cgggtgactt ttatgtgaca gttcttttgg
    59521 atttcacgct ggtttgtggg gaaatccgta acctcaaggc tcgagaagtg gtgttgggtt
    59581 atgacttgtc tgaggaagaa gaacaaatcc tcagccgcca gatgaatctg gtactctctt
    59641 atgaaaaaga aagctttgaa gaccttcatt tattggattt gcgattggca acggtggagc
    59701 aaacggcatc tagtaagctg ctccggtatg ttcatcggac tcagatgagg gaattgaacc
    59761 acctcaaacc tgttatccgc tacgaaatta aggatttctt gcagatggat tatgcgacca
    59821 aggctagtct ggatttggtt gagaatgctc gctcaggtaa gaaacaaggc agtcttttct
    59881 ggcttttgga tgaaaccaaa acggctatgg ggatgcgtct cttgcgttct tggattcatc
    59941 gccccttgat tgataaggaa cgaatcgtcc aacgtcaaga agtagtgcag gtctttctcg
    60001 accatttctt tgagcgtagt gacttgacag acagtctcaa gggtgtttat gacattgagc
    60061 gcttggctag tcgtgtttct tttggcaaaa ccaatccaaa ggatctcttg cagttggcga
    60121 ctaccttgtc tagtgtgcca cggattcgtg cgattttaga agggatggag caacctgctc
    60181 tagcctatct catcgcacaa ctggatgcaa tccctgagtt ggagagtttg attagcgcag
    60241 cgattgctcc tgaagctcct catgtgatta cagatggggg aattatccgg actggatttg
    60301 atgagacttt agacaagtat cgttgcgttc tcagagaagg gactagctgg attgctgaga
    60361 ttgaggctaa ggagcgagaa aactctggta tcagcacgct caagattgac tacaataaaa
    60421 aggatggcta ctattttcat gtgaccaatt cgcaactagg aaatgtgcca gcccactttt
    60481 tccgcaaggc gacgctgaaa aactcagaac gctttggaac cgaagaatta gcccgtatcg
    60541 agggagatat gcttgaggcg cgtgagaagt cagccaacct cgaatacgaa atatttatgc
    60601 gcattcgtga agaggtcggc aagtacatcc agcgtttaca agctctagcc caaggaattg
    60661 cgacggttga tgtcttacag agtctggcgg ttgtggctga aacccagcat ttgattcgac
    60721 ctgagtttgg tgacgattca caaattgata tccggaaagg gcgccatgct gtcgttgaaa
    60781 aggttatggg ggctcagacc tatattccaa atacgattca gatggcagaa gataccagta
    60841 ttcaactgat tacagggcca aacatgagtg ggaagtctac ctatatgcgt cagttagcca
    60901 tgacggcggt tatggcccag ctgggttcct atgttcctgc tgaaagcgcc catttaccga
    60961 tttttgatgc gatttttacc cgtatcggag cagcagatga cttggtttcg ggtcagtcga
    61021 cctttatggt ggagatgatg gaggccaata atgccatttc gcatgcgacc aagaactctc
    61081 tcattctctt tgatgaattg ggacgtggaa ctgcaactta tgacgggatg gctcttgctc
    61141 agtccatcat cgaatatatc catgagcaca tcggagctaa gaccctcttt gcgacccact
    61201 accatgagtt gactagtctg gagtctagtt tacaacactt ggtcaatgtc cacgtggcaa
    61261 ctctggagca ggatgggcag gttaccttcc ttcacaagat tgaaccggga ccagctgata
    61321 aatcctacgg tatccatgtt gccaagattg ctggcttgcc agcagacctt ttagcaaggg
    61381 cggataagat tttgactcag ctagagaatc aaggaacaga gagtcctcct cccatgagac
    61441 aaactagtgc tgtcactgaa catatttcac tctttgatag ggcagaagag catcctatcc
    61501 tagcagaatt agctaaactg gatgtgtata atatgacacc tatgcaggtt atgaatgtct
    61561 tagtagagtt aaaacagaaa ctataaaacc aagactcact agttaatcta gctgtatcaa
    61621 ggagacttct ttgacaattc tccacttttt tgctagaata acatcacaca aacagaatga
    61681 aaaggagctg acgcattgtc gctccctttt gtctattttt taaggagaaa gtatgctgat
    61741 tcagaaaata aaaacctaca agtggcaggc cctggcttcg ctcctgatga caggcttgat
    61801 ggttgctagt tcacttctgc aaccgcgtta tctgcaggaa gtcttaggcg ccctccttac
    61861 tgggaaatat gaagctattt atagtatcgg ggcttggttg attggtgtgg ccgtagtcgg
    61921 tctagttgct ggtggactca atgttgtcct cgcagcctat attgcccaag gagtttcatc
    61981 cgaccttcgg gaggatgcct tccgtaaaat tcaaaccttt tcttatgctg atattgaaca
    62041 atttaatgcg ggaaatctag tcgttcgaat gacaaatgat atcaaccaga ttcagaacgt
    62101 tgtcatgatg accttccaaa ttcttttcag acttcccctc ttgttcatcg gttcgtttat
    62161 cctagcggtt caaaccttac cttctctgtg gtgggtgatt gttctcatgg tagtcttgat
    62221 ttttggtttg actgctgtca tgatgggaat gatggggcct cgttttgcca agtttcaaac
    62281 ccttcttgag cgcatcaatg ccattgccaa ggaaaattta cgtggcgttc gtgtggtcaa
    62341 gtcctttgtc caagaaaaag agcaatttgc taagtttaca gaggtctcag acgagcttct
    62401 tggtcaaaac ctttacattg gttatgcctt ttcagtagtg gaacccttta tgatgttggt
    62461 tggttacggg gcggtcttcc tctctatttg gctggtcgcg ggaatggttc agtcggatcc
    62521 gtctgttgtt ggttccatcg cttcttttgt taattaccta agccagatta tctttaccat
    62581 tgttatggtt ggatttttgg gaaattctgt cagccgtgcc atgatttcca tgcgtcgtat
    62641 tcgagaaatt cttgacgcag agccagctat gaccttcaag gatatcccag atgaagagtt
    62701 ggttggaagt cttagctttg aaaatgtgac ctttacctat ccaatggaca aggaaccgat
    62761 gctgaaagat gtgagcttta ctattgaacc tggtcaaatg gttggtgtag ttggagcgac
    62821 tggtgcagga aagtcaacct tggctcaatt gattccacgt ctctttgatc cacaggacgg
    62881 ggccattaaa atcggtggca aggatattcg agaagtgagt gaaggaaccc tgcgtaaaac
    62941 agtttccatc gttctccaac gtgccattct ttttagtgga acgattgcag ataacttgag
    63001 acaggggaag gggaatgcta ctctatttga aatggagcgc gcagccaata ttgcccaggc
    63061 tagtgaattc attcatcgta tggagaaaac ctttgaaagt ccagttgaag aacggggaac
    63121 caatttctct ggtggacaaa aacaaaggat gtcgattgcg cgtgggattg tcagcaatcc
    63181 acgtattctg atttttgatg attcgacctc agccttggat gccaaatcag agcgcttggt
    63241 gcaagaagct ttgaataagg acttgaaggg gacgacaacc attattattg ctcaaaaaat
    63301 tagctcggtt gtccatgcag acaagatctt ggttctaaat caaggacgat tgattggtca
    63361 aggcacgcat gcagacttgg ttgccaacaa tgccgtttac cgtgaaatct atgaaacaca
    63421 gaaatgaaag acaaactata agaaaagtca atagttttat ctaaactatt tcttatttca
    63481 atttgatgat ttggcgatga ttttagagca cggcaaaaag ctattgaaaa agtccatttt
    63541 ttcaaaggta atcctgtgtt aatttcagaa attatatcac tttttgttcg tcaaatggca
    63601 gctctttttt aggatataaa acagggttcg gataagtttt tttgcaaggt ggatgatggc
    63661 tacattgtaa tgttttcctt gttctaattt agtcttaaga taggccttaa aagcaggcga
    63721 aaagcgaggg catgctttgg cagcttgtat gagtacctac cgcagatgag gggaactccg
    63781 tttgaccatt cttcctgcta aatcaatctg atctgactga taaatagaag aatccagtcc
    63841 agcgaaagct tgtaattgag caggattatc aaaggcatga atatttcgaa tctcagctaa
    63901 aatgaccgcc cctaaacgat ccccaatccc agtaaccgtc gtgatgaccg agttgaactc
    63961 agccatcaag tcattgacac atgtttccgc cttgtcaatg agcctcttgt aatgtttgat
    64021 gttttcatta cacgagataa aacgtctatg cgttatcaaa ctcattacca attaaaacaa
    64081 aaagctgtgg ttagatcctt tcggaaattg tcaagcgatt ggaggaaatg aactaatcca
    64141 cagcggctta ttccaagtat accacttggg ctttggcagt agctaactgc gctaaatata
    64201 atataaggag gagtaaaatg aagacagttc aatttttttg gcattatttt aaggtctaca
    64261 agttctcatt tgtagttgtc atcctgatga ttgttctggc gacttttgcc caagccctct
    64321 ttccagtctt ttctggacaa gcggtgacgc agctagccaa tttagttcaa gcttatcaaa
    64381 atggcaatcc agaacttgta tggcaaagcc tatcaggaat catggtcaat cttggcctgc
    64441 tggttttggt tctatttatc tctagtgtaa tatacatgtg tctcatgacg cgcgtgattg
    64501 cagaatcgac caacgagatg cgcaaaggcc tctttggtaa gcttgctcag ttgacggttt
    64561 ctttctttga ccgtcgacaa gatggcgata tcctgtctca ttttaccagt gatttggata
    64621 atatcctcca agcctttaac gaaagcttga ttcaggtcat gagcaatatt gttttataca
    64681 ttggtctgat tcttgtcatg ttttcgagaa atgtgacgct ggctctcatc accattgcca
    64741 gcaccccatt ggctttcctt atgctgattt tcatcgtgaa aatggcacgc aaatacacca
    64801 acctccagca gaaagaggta gggaagctca acgcctatat ggatgagagc atctcaggcc
    64861 aaaaagccgt gattgtgcaa ggaattcaag aggatatgat ggcaggattt cttgaacaaa
    64921 atgagcgcgt gcgcaaggca acctttaaag gaagaatgtt ctcaggaatt cttttccctg
    64981 tcatgaatgg gatgagcctg attaatacag ccatcgtcat ctttgctggt tcggctgtac
    65041 ttttgaatga taagtctatt gaaacaagta cagccctagg tttgattgtt atgtttgcac
    65101 aattttcaca gcagtactac cagcctatta tccaagttgc agcgagttgg ggaagccttc
    65161 agttggcctt tactggagct gaacgaattc aggaaatgtt tgatgcagag gaggaaatcc
    65221 gacctgaaaa ggctccaacc ttcactaagt tgcaagaaag tgttgaaatc agtcatatcg
    65281 atttttcata cttgcctgat aaacctattt tgaaagatgt cagcatttct gcccctaaag
    65341 gccagatgac agcagttgtt gggccgacag gttcaggaaa aacgactatt atgaacctca
    65401 tcaatcgctt ttatgatgtt gatgctggtg gtatttattt tgatggtaaa gacattcgtg
    65461 gctatgactt agatagtctt agaagcaagg tgggaattgt attgcaagat tcggtcttgt
    65521 ttagcggaac gattagagac aatatccgat ttggtgtgtc agatgctagt caggaaatgg
    65581 ttgaggtagc agcaaaagca acccacattc acgactatat cgaaagtttg cctgataagt
    65641 acgatactct tattgatgat gaccagagca tcttttcaac agggcagaag caattgattt
    65701 caatcgctcg aaccctgatg acagatccag aagttctcat tctcgatgaa gcaacttcaa
    65761 acgtagatac ggtgacagaa agcaagattc agcatgccat ggaggtggtt gtagcaggta
    65821 gaactagttt cgtcattgcc caccgcttga aaaccattct caatgcagat cagattattg
    65881 tccttaaaga tggagaagtc attgaacgtg gtaaccacca tgaacttttg aagctaggtg
    65941 gcttttattc agaactctat cacaatcaat ttgttttcaa ataagaaaga agttgtccta
    66001 tgtgggcagc tttttcttgt ccataaaaaa tgtttatcac agccttaaaa aaaacatatt
    66061 agacgaaagt cattttgagt gatatgatag gactatcgtt agcattcgaa aggagaggca
    66121 tcatggctag aacggttgta ggagttgctg caaatctatg tcccgtagac gcagaaggca
    66181 aaatcattca ttcatctgta tcttgtagat tcgcagagat cattcgtcaa gtcggtggtc
    66241 tccctttagt cattcctgtt ggtgatgagt cagttgtacg tgattatgtg gaaatgattg
    66301 acaaactcat tttgacagga ggccaaaatg ttcatcctca gttttatgga gagaaaaaga
    66361 ccgtcgaaag cgatgattac aatctggtcc gtgacgaatt tgaattggca ctcttgaagg
    66421 aagcgcttcg tcagaataaa ccaattatgg caatctgtcg cggtgtccaa cttgtcaatg
    66481 ttgcctttgg tggaaccctc aatcaagaaa tcgaaggtca ctggcaagga ctacctttcg
    66541 ggacatctca ctctattgag acagtagaag gaagcgtggt ggctaagcta tttgggaaag
    66601 aaagtcaggt caactcagtc catcgtcaaa gcattaaaga tttggcacct aatttccgtg
    66661 taactgctat tgattcaaga gaccaaacta ttgaagcgat tgagtctatc gacgagcacc
    66721 gcattatcgg tttacagtgg catccagagt ttctggttaa tgaagaagat ggcaatttag
    66781 aattatttga gtatttattg aatgaactgt aacgattgga acatctggtc gttctttctt
    66841 ttattttttc aaaattttta gaatgtggca ttttacgcaa acgtttgaat tctgataaaa
    66901 attggagaaa ttcgacaaaa aaacttgaaa aaaacgaagg taagcgttat gatagaaaag
    66961 aagaaatatt ggaggaagaa catgtcacat attaaatttg attattcaaa agttttagac
    67021 aaatttgttg caccacatga agtggaatac atgcaatcac aagtaacagc agcagatgaa
    67081 ttgatccgta aaggaactgg tgctggtagc gacttcttgg gatggttgga ccttcctgaa
    67141 aaatacgatc gcgaagaatt tgaccgcatc ttgaaagctg ctgagcaaat caagtcagac
    67201 agcgatgttt tggttgtgat cggtattggt ggatcttacc ttggtgcaaa agcagcaatc
    67261 gacttcttga atcaccattt tgctaacttg caaacaaaag aagaacgcaa agctccacaa
    67321 atcctttacg caggaaactc aatctcatct acttaccttg ctgacttggt agagtatgtt
    67381 gcagacaaag acttctcagt aaacgtaatt tctaaatcag gtacaacaac tgaaccagcg
    67441 attgctttcc gtgtctttaa agaactcttg gttaagaaat acggtcaaga agaagctaac
    67501 aaacgtatct atgcaacaac tgaccgccaa aagggtgctg ttaaggttga agcagatgct
    67561 aacggttggg gaacatttgt tgttccagat gatatcggtg gacgcttctc agtattgaca
    67621 gccgttggtt tgcttccaat cgcagcatca ggagctgaca tcaaagctct tatggaaggt
    67681 gcgaatgcag ctcgcaaaga ctacacttca gacaaaatct ctgaaaacga agcttaccaa
    67741 tacgcagctg ttcgtaacat cctttatcgt aaaggctatg caactgagat cttggtaaac
    67801 tatgagccat cacttcaata cttctcagaa tggtggaaac aattggctgg tgaatcagaa
    67861 ggaaaagacc aaaaaggtat ctacccaact tcagccaact tctcaactga cttgcactca
    67921 cttggtcaat ttatccaaga aggaactcgt atcatgtttg aaacagttgt ccgtgttgac
    67981 aaacctcgta aaaacgtgct tattcctact ttggaagaag accttgacgg acttggttac
    68041 cttcaaggaa aagacgttga ctttgtaaac aaaaaagcaa ctgacggtgt tcttcttgcc
    68101 cacacagatg gtgatgtacc aaacatgtat gtgactcttc cagagcaaga cgctttcact
    68161 cttggttaca ctatctactt cttcgaattg gcaattgccc tttcaggtta cttgaatgct
    68221 atcaacccat ttgaccaacc aggtgttgaa gcttataaac gtaacatgtt tgcccttctt
    68281 ggaaaaccag gatttgaaga attgagcaaa gaacttaacg cacgtctata atagaagaaa
    68341 agagtggttt gcccactctt tttactctct ttatccatag aaattggact cagccaagac
    68401 ttgtgatata atatagaaag caaaaaggca gacgcctaga taataggaga aactatgtca
    68461 aaagatatcc gcgtacgtta cgcaccaagt ccaacaggac tactacacat cggaaatgct
    68521 cgtacagcat tgtttaatta cttgtatgcg cgccatcatg gtggaacatt tctcatccgt
    68581 atcgaagata ctgaccgtaa acgccatgtc gaggatggtg aacgttcaca acttgaaaac
    68641 cttcgctggt taggcatgga ttgggatgaa agtccagaat cacatgagaa ttatcgccag
    68701 tctgagcgtt tggacttgta tcaaaaatac attgaccaac tattagctga aggaaaagcc
    68761 tataaatctt acgttacaga agaagagttg gcagctgaac gcgaacgcca agaagtagct
    68821 ggcgaaacac cacgctacat caatgaatac cttggtatga gtgaagaaga aaaagcagct
    68881 tacatcgcag aacgtgaagc agcagggatc atcccaactg ttcgtttggc tgtcaatgag
    68941 tcaggtatct acaagtggca tgatatggtc aaaggcgata tcgaatttga aggtggcaat
    69001 atcggtggtg actggattat ccaaaagaaa gacggttacc caacttacaa ctttgccgtt
    69061 gccatcgatg accacgatat gcaaatctct catgttatcc gtggagatga ccatattgct
    69121 aatacaccaa aacagcttat ggtctatgaa gctcttggtt gggaagctcc agagttcggt
    69181 cacatgacct tgattatcaa ctctgagact ggtaagaagt tatctaaacg tgatactaat
    69241 acacttcaat ttatcgaaga ttaccgaaag aaaggttacc ttccagaagc agtctttaac
    69301 tttattgctc ttcttggttg gaacccaggt ggtgaagatg agattttctc tcgtgaagaa
    69361 ctcattaaac tttttgatga aaaccgcctc agcaagtcac cagcagcctt tgatcagaaa
    69421 aaactagact ggatgagcaa tgattatatc aagaatgcag accttgaaac catctttgaa
    69481 atggcaaaac cattcttaga ggaagcaggc cgtttgactg acaaggctga aaaattagtt
    69541 gagctctata aaccacaaat aaaatcagta gatgagatta tcccattgac agatcttttc
    69601 ttctcagatt tcccagaatt gacagaagca gagcgcgaag tcatgacggg tgaaacagtt
    69661 ccaacagttc ttgaagcatt caaagcaaaa cttgaagcga tgacagatga taaatttgtg
    69721 acagaaaata tcttcccaca aattaaagca gtccaaaaag aaacaggtat taaagggaaa
    69781 aatcttttca tgcctattcg tatcgcagtt tcaggcgaaa tgcatgggcc agaattacca
    69841 gatacaattt tcttgcttgg acgtgaaaaa tcaattcagc atatcgaaaa catgctaaaa
    69901 gaaatctcta aataaagagg atacaataat ggacatctgg gaaaagatgt acgaagaagc
    69961 acagaaacta tacaatccac atgaagtatc agactttgtt tatgccaatc atgttgtagc
    70021 tgcagtagaa gcagaagatg gacaaatatt tacaggattc tgtatggagg gaacctgtgg
    70081 tgttttccat ctctgcgcag aacgggcggc cctcttcaat atgtaccaat tttcaggaca
    70141 aactaaggtt aagaaagtat tagcctttcg agacaaacca ccttatggtg gaagttcagc
    70201 catgccttgc ggtgcttgta gagaattcct tttagagctt aatgctgaaa ataaagatgc
    70261 agaattcatg atggactata atataagaaa aacagttaaa gtcgcagaac taatccctta
    70321 ttggtgggga aaagaacgtg cttctaagtt taatgagcga tagaagagtc agtataattc
    70381 tggctctttt tactataagt tgc
//
LOCUS       DAVKZI010000005        69193 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKZI010000005 DAVKZI010000000
VERSION     DAVKZI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.005"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            2..74
                     /locus_tag="VXB18_000382"
     tRNA            2..74
                     /locus_tag="VXB18_000382"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VXB18_000383"
     tRNA            99..171
                     /locus_tag="VXB18_000383"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VXB18_000384"
     tRNA            177..258
                     /locus_tag="VXB18_000384"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VXB18_000385"
     tRNA            277..349
                     /locus_tag="VXB18_000385"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VXB18_000386"
     tRNA            372..443
                     /locus_tag="VXB18_000386"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VXB18_000387"
     tRNA            451..536
                     /locus_tag="VXB18_000387"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VXB18_000388"
     tRNA            546..619
                     /locus_tag="VXB18_000388"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VXB18_000389"
     tRNA            635..708
                     /locus_tag="VXB18_000389"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VXB18_000390"
     tRNA            714..787
                     /locus_tag="VXB18_000390"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VXB18_000391"
     tRNA            801..874
                     /locus_tag="VXB18_000391"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VXB18_000392"
     tRNA            885..974
                     /locus_tag="VXB18_000392"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            985..1058
                     /locus_tag="VXB18_000393"
     tRNA            985..1058
                     /locus_tag="VXB18_000393"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1019..1021,aa:Met,seq:cat)
     gene            1062..1134
                     /locus_tag="VXB18_000394"
     tRNA            1062..1134
                     /locus_tag="VXB18_000394"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Phe,seq:gaa)
     gene            1154..1224
                     /locus_tag="VXB18_000395"
     tRNA            1154..1224
                     /locus_tag="VXB18_000395"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Gly,seq:tcc)
     gene            1260..1333
                     /locus_tag="VXB18_000396"
     tRNA            1260..1333
                     /locus_tag="VXB18_000396"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1294..1296,aa:Ile,seq:gat)
     gene            1340..1427
                     /locus_tag="VXB18_000397"
     tRNA            1340..1427
                     /locus_tag="VXB18_000397"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1374..1376,aa:Ser,seq:gct)
     gene            complement(1560..1997)
                     /locus_tag="VXB18_000398"
     CDS             complement(1560..1997)
                     /locus_tag="VXB18_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0381658.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2204..3139)
                     /locus_tag="VXB18_000399"
     CDS             complement(2204..3139)
                     /locus_tag="VXB18_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0381659.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKA
                     KAASLFKATAPITRNELIIEIWRAFFETPSEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3136..3996)
                     /locus_tag="VXB18_000400"
     CDS             complement(3136..3996)
                     /locus_tag="VXB18_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0381660.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVNLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4104..6266
                     /locus_tag="VXB18_000401"
     CDS             4104..6266
                     /locus_tag="VXB18_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0381661.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRTTPLETRGHVAMMGNLGYELDLTSLSDEEKAEIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYKNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     ELQENGEVYSGAELMYAGLTVILSQGDFLSKQYIFRRL"
     gene            6301..7560
                     /locus_tag="VXB18_000402"
     CDS             6301..7560
                     /locus_tag="VXB18_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0381662.1"
                     /translation="MKWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7574..8440
                     /locus_tag="VXB18_000403"
     CDS             7574..8440
                     /locus_tag="VXB18_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0381663.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            8454..9287
                     /locus_tag="VXB18_000404"
     CDS             8454..9287
                     /locus_tag="VXB18_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0381664.1"
                     /translation="MKQDERKALIGKYILLILGSVLLLVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            9288..9368
                     /locus_tag="VXB18_000405"
                     /pseudo
     CDS             9288..9368
                     /locus_tag="VXB18_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9507..10949
                     /gene="gtfA"
                     /locus_tag="VXB18_000406"
     CDS             9507..10949
                     /gene="gtfA"
                     /locus_tag="VXB18_000406"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0381665.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGGDLIRLDAFAYAVKKLYTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKVLLNLFSFRNRSEAFDLEGTTEIETPTAQSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            11087..12280
                     /locus_tag="VXB18_000407"
     CDS             11087..12280
                     /locus_tag="VXB18_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0381666.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12967..14946
                     /locus_tag="VXB18_000408"
     CDS             12967..14946
                     /locus_tag="VXB18_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0381667.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15013..16509
                     /locus_tag="VXB18_000409"
     CDS             15013..16509
                     /locus_tag="VXB18_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381668.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16509..17435
                     /locus_tag="VXB18_000410"
     CDS             16509..17435
                     /locus_tag="VXB18_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381669.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINVVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17444..18511
                     /locus_tag="VXB18_000411"
     CDS             17444..18511
                     /locus_tag="VXB18_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381670.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18522..19448
                     /locus_tag="VXB18_000412"
     CDS             18522..19448
                     /locus_tag="VXB18_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381671.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(19523..20722)
                     /locus_tag="VXB18_000413"
                     /pseudo
     CDS             complement(19523..20722)
                     /locus_tag="VXB18_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20878..21588)
                     /gene="treR"
                     /locus_tag="VXB18_000414"
     CDS             complement(20878..21588)
                     /gene="treR"
                     /locus_tag="VXB18_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0381672.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21773..23740
                     /gene="treP"
                     /locus_tag="VXB18_000415"
     CDS             21773..23740
                     /gene="treP"
                     /locus_tag="VXB18_000415"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0381673.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEATKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELISPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            23918..25543
                     /gene="treC"
                     /locus_tag="VXB18_000416"
     CDS             23918..25543
                     /gene="treC"
                     /locus_tag="VXB18_000416"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0381674.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIKGPIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25799..26047
                     /locus_tag="VXB18_000417"
     CDS             25799..26047
                     /locus_tag="VXB18_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0381675.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26254..27048
                     /gene="racE"
                     /locus_tag="VXB18_000418"
     CDS             26254..27048
                     /gene="racE"
                     /locus_tag="VXB18_000418"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0381676.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27045..28016
                     /locus_tag="VXB18_000419"
     CDS             27045..28016
                     /locus_tag="VXB18_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0381677.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27992..28513
                     /locus_tag="VXB18_000420"
     CDS             27992..28513
                     /locus_tag="VXB18_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0381678.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28510..28971
                     /locus_tag="VXB18_000421"
     CDS             28510..28971
                     /locus_tag="VXB18_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0381679.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVLPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28962..29702
                     /gene="xerD"
                     /locus_tag="VXB18_000422"
     CDS             28962..29702
                     /gene="xerD"
                     /locus_tag="VXB18_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0381680.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASKRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29702..30430
                     /locus_tag="VXB18_000423"
     CDS             29702..30430
                     /locus_tag="VXB18_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0381681.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30449..31018
                     /locus_tag="VXB18_000424"
     CDS             30449..31018
                     /locus_tag="VXB18_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0381682.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31005..31727
                     /locus_tag="VXB18_000425"
     CDS             31005..31727
                     /locus_tag="VXB18_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0381683.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31727..31969
                     /gene="yidD"
                     /locus_tag="VXB18_000426"
     CDS             31727..31969
                     /gene="yidD"
                     /locus_tag="VXB18_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0381684.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32194..33159)
                     /locus_tag="VXB18_000427"
     CDS             complement(32194..33159)
                     /locus_tag="VXB18_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0381685.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEISFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33255..34007)
                     /locus_tag="VXB18_000428"
     CDS             complement(33255..34007)
                     /locus_tag="VXB18_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0381686.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIDSWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34004..34960)
                     /locus_tag="VXB18_000429"
     CDS             complement(34004..34960)
                     /locus_tag="VXB18_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0381687.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(34950..35909)
                     /locus_tag="VXB18_000430"
     CDS             complement(34950..35909)
                     /locus_tag="VXB18_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381688.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36332..37033)
                     /locus_tag="VXB18_000431"
     CDS             complement(36332..37033)
                     /locus_tag="VXB18_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV0381689.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKVYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPINPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKTFGDDYDTH
                     DGSCIRDYIYVLDLA"
     gene            37433..38497
                     /gene="pepA"
                     /locus_tag="VXB18_000432"
     CDS             37433..38497
                     /gene="pepA"
                     /locus_tag="VXB18_000432"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0381690.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38519..38815
                     /locus_tag="VXB18_000433"
     CDS             38519..38815
                     /locus_tag="VXB18_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0381691.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39497..39940
                     /locus_tag="VXB18_000434"
     CDS             39497..39940
                     /locus_tag="VXB18_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0381692.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            39944..40708
                     /locus_tag="VXB18_000435"
     CDS             39944..40708
                     /locus_tag="VXB18_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0381693.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40723..41451
                     /locus_tag="VXB18_000436"
     CDS             40723..41451
                     /locus_tag="VXB18_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381694.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41444..42964
                     /locus_tag="VXB18_000437"
     CDS             41444..42964
                     /locus_tag="VXB18_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0381695.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43309..44115
                     /locus_tag="VXB18_000438"
     CDS             43309..44115
                     /locus_tag="VXB18_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0381696.1"
                     /translation="MHTYLQKKIENIKATLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
     gene            complement(44281..44817)
                     /locus_tag="VXB18_000439"
     CDS             complement(44281..44817)
                     /locus_tag="VXB18_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0381697.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            44950..45840
                     /locus_tag="VXB18_000440"
     CDS             44950..45840
                     /locus_tag="VXB18_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0381698.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            46084..46437
                     /locus_tag="VXB18_000441"
     CDS             46084..46437
                     /locus_tag="VXB18_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0381699.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46438..47475
                     /locus_tag="VXB18_000442"
     CDS             46438..47475
                     /locus_tag="VXB18_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0381700.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47521..48528)
                     /gene="galR"
                     /locus_tag="VXB18_000443"
     CDS             complement(47521..48528)
                     /gene="galR"
                     /locus_tag="VXB18_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0381701.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVVEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48692..49870
                     /locus_tag="VXB18_000444"
     CDS             48692..49870
                     /locus_tag="VXB18_000444"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0381702.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYKVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49889..51370
                     /locus_tag="VXB18_000445"
     CDS             49889..51370
                     /locus_tag="VXB18_000445"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0381703.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEETVRLETIEDSQTAREILGTELMDLVTPCPSQVNSDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDETPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            51440..51844
                     /locus_tag="VXB18_000446"
     CDS             51440..51844
                     /locus_tag="VXB18_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0381704.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEDRQVRI"
     gene            52001..52855
                     /locus_tag="VXB18_000447"
     CDS             52001..52855
                     /locus_tag="VXB18_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV0381705.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            52881..53651
                     /locus_tag="VXB18_000448"
     CDS             52881..53651
                     /locus_tag="VXB18_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0381706.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            53638..54504
                     /locus_tag="VXB18_000449"
     CDS             53638..54504
                     /locus_tag="VXB18_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HEV0381707.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(54591..55853)
                     /locus_tag="VXB18_000450"
     CDS             complement(54591..55853)
                     /locus_tag="VXB18_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0381708.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(55853..56434)
                     /locus_tag="VXB18_000451"
     CDS             complement(55853..56434)
                     /locus_tag="VXB18_000451"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0381709.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(56834..56929)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(57312..57551)
                     /locus_tag="VXB18_000452"
     CDS             complement(57312..57551)
                     /locus_tag="VXB18_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0381710.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(57551..57694)
                     /locus_tag="VXB18_000453"
     CDS             complement(57551..57694)
                     /locus_tag="VXB18_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0381711.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(57706..58533)
                     /gene="xth"
                     /locus_tag="VXB18_000454"
     CDS             complement(57706..58533)
                     /gene="xth"
                     /locus_tag="VXB18_000454"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0381712.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            58667..59123
                     /locus_tag="VXB18_000455"
                     /pseudo
     CDS             58667..59123
                     /locus_tag="VXB18_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            59195..59572
                     /locus_tag="VXB18_000456"
     CDS             59195..59572
                     /locus_tag="VXB18_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0381713.1"
                     /translation="MKCLIDGKPTLLIKNGNIDPEACRSVGLSASDVALKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYK"
     gene            59778..61523
                     /locus_tag="VXB18_000457"
     CDS             59778..61523
                     /locus_tag="VXB18_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381714.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAAVEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMAGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            61513..63264
                     /locus_tag="VXB18_000458"
     CDS             61513..63264
                     /locus_tag="VXB18_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381715.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            63437..64129
                     /locus_tag="VXB18_000459"
     CDS             63437..64129
                     /locus_tag="VXB18_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0381716.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTKKGLSVDQAYVEHVLPEKMHYNLAYLREFSFLGDI
                     KIMFQTVFEVLK"
     gene            64172..65398
                     /locus_tag="VXB18_000460"
     CDS             64172..65398
                     /locus_tag="VXB18_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0381717.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWRANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            66529..68688
                     /gene="pfbA"
                     /locus_tag="VXB18_000461"
     CDS             66529..68688
                     /gene="pfbA"
                     /locus_tag="VXB18_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0381718.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVMN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            68672..68968
                     /locus_tag="VXB18_000462"
     CDS             68672..68968
                     /locus_tag="VXB18_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381719.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
BASE COUNT        20250 a        12670 c        15418 g        20855 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt gagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttaacgcggg atggagcagc tcggtagctc gtcgggctca
     1021 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
     1081 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattttat
     1141 tgatagtatt tatgcgggtg tagtttagtg gtaaaactac agccttccaa gctgttgtcg
     1201 cgagttcgat tctcgtcacc cgctttgaac tttgttcaaa ttaccaagtt ttttaacttg
     1261 ggcgcgtagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt
     1321 ccactcgtgc ccattaattg gagaattact caagaggctg aagaggacgg tttgctaaat
     1381 cgttaggtcg ggtaactggc gcaagggttc gaatccctta ttctccgttt taatgagagt
     1441 ttgtaactct cttttttatt tttagagaca ataaagcttc agatccgtaa aacttaattg
     1501 aattactaat ctgaagttat ttttatggct ctttgtcaac tgtagtgggt tgaagtcagc
     1561 taagctcgag aaaggacaaa tttcgtcctt tcttttttga tgttcaaagc gataaaaatc
     1621 cgttttttaa agttttcaaa gtttcgaaaa ccaaaggcat tgcacttgat aagtttgatg
     1681 agattattgg tcgcttccag tttggcgtta gaatagtgta gttgaagggc gttgacaatc
     1741 ttttctttat ctttgaggaa ggttttaaag acagtctgaa aaataggatg aacctgctta
     1801 agattgtcct caataagtcc gaaaaatttc tctggttcct ttttcttcat tagacttcca
     1861 caatcagggc aagatggagc ctcataatcc agcttagcga taatttcttt gtgggtatcc
     1921 atattgatga tatctagaat cttgatgttt gggtctttaa tatcgagcag ttttgtgata
     1981 aaatgtaatt gttccatatg aatctttcta atgatggttt tgtcgctttt cattataggt
     2041 catatgggac tttttttcta caacaaaata ggctccataa tatctataag ggatttaccc
     2101 actacaaata ttatagagcc aataaaactt cagatccgta aaacttaatt gaattactaa
     2161 tctgaagtta tttttatatc gtttatatta taattgtgtt attttacttc caactattga
     2221 gagaaatttc gccactattt agccagattt cttttccgtt atcacattga actaaaagtt
     2281 ttccattctc tgagatgtct ttagcaagtc ccttgtagtc tttttgctct agtgtgaaag
     2341 tgacttcttt tcctagaatg aatgactgtt ttttgtatag gtataatagc tcttctgatg
     2401 gtgtttcgaa gaaagcacgc cagatttcta tgatcaattc attccttgtt ataggagctg
     2461 tagctttaaa taagctggca gcttttgctt ttaattcctg agggaagtct ttaatagtga
     2521 aattgatacc tactccaata atgatatctg tgactaagcc agtttctaca gaggtcattg
     2581 cttcagtaag gattcctcca attttatgat tgtttagata gatatcattg acccatttta
     2641 tgtcgacatc tattaaagtt aggttcttaa tggctttgta gacagctcca gctacaagta
     2701 gtgtgtagga tggtaatttg tcatagggga gatttggttt aagatggagt gtcatataaa
     2761 taccaccttg tggtgagtag aaggaacgtt gaaaacggcc tcggcctgct gtttgatagg
     2821 aagctagata gagggtattt gcttcatggc ctaaatcaat tgcttctttt gcatctagtt
     2881 gtgttgattt tgtttcgggt ttaaagctga ctttaattgg aagattttct tctagaatct
     2941 ctggaagaat aaggtcacca ttcattagtt tatatcctct atttttgata ctatcaattt
     3001 caatgccttc ttgttctagt cgcttgatag ctttccaaat tgatgttcgg cttagggata
     3061 gtttttctgc gattttttct ccgctgatat agtcggtttc tttagatagg atttggtaga
     3121 cagcttggta ggatttcata atgttgcctt tctcactagt tggtattgag agtattcttt
     3181 tcttgtatga cttggagtct gattaaagta ttgtttataa gctttcgaaa aatggagtgg
     3241 atctgaaaaa cctaccgagt atgcaattac cttgatggac tcttgggtat tttcgagaag
     3301 ttgtctagct cggtgcattc gaacgtagag taggtattct ttgggtgata aggtattaaa
     3361 ttctttgaat acgcttgata agtagcttct gtgaacggat agttcttttg ctaaatcttg
     3421 aattgtaagt gattgaggat agtggctatc aattaatcgt ttgcattcaa gatagagttg
     3481 gtgggttgat gaaatattct tttttttctg attgggagca atagttccca gatgaaacat
     3541 cagttcatga agttgtccca tgatatggag ttgagctaat tcacttgatt ttgtaatctg
     3601 agcgaagcgg acaatgtctg agatgagttt tgcagtagtc tgggtatgac aagtttcaga
     3661 ttggatgaga taggattgat cagaaatttg agaaagagca aaataatcag gggatttccc
     3721 tccagtgatt cctaaccagt agtaggccca aggttcttta ctatctgctt gataaaaggt
     3781 tagttcctct ggttttaata gaaagaaatc tccttctttt aaattaacaa ttttaccctt
     3841 gtaatgaaat tttccttgtc ctttagtaat gtaatgtagg acgtatgtat cacgaatggc
     3901 tggaccaaaa gagtaattag gtgtgcattc ctcatatcca taaaagctta gggcaaggtc
     3961 gattgttcca gtctggtatt ctgaaaaaac taacatgtgc tacctcctac ctaacatttt
     4021 accatattct tgagacattt ttctatttta gaaagcgatt tcaggtgata aaatataatc
     4081 aataaagtga tgaggtgaag taaatgggag ttaggataga gaataatcta ttttatgttg
     4141 agagtaaaaa tctaagtttg attattgaaa atcgaaatgg ctacttactt ttgaaacatt
     4201 taggaaagac tattaagaac tataaaggtt ccaatagtgt ttatgaacga gaccatgcct
     4261 tttcaggaaa tccaacggct actaatcgaa cctttagttt agatactcag cgacagattt
     4321 ttggacaaca tggcttagga gattttagga aaccaaccat acaggttcag catagtgtaa
     4381 ctgaagtaac agactttcga tttgtagaag caaagatttt aaaaggtcag aatggtccac
     4441 agggcttacc ttctccacat agcatggacg atacagagac tcttgtctta atgttagaag
     4501 attctaaggc tcaacttagt ctgactttgt attatactac ttttaataat gatgcgacta
     4561 ttgctagcta cagtaaatta gataataata gtaatcagga agttgtcatc cataaagatt
     4621 tttcttttat ggctgatttt ccagctgcag attacgaaat agtaactctg cagggtgctt
     4681 atgctcgtga aaagactgtt agacgtcaac aggtagaaca aggaatcttt tcgattagct
     4741 caaaccgagg tgcttctggt catgctcaaa caccagctct tctactatgc gaacaaggag
     4801 tcacagagga tgctgggaat gtgtttgcta ttcaactaat gtatagtggc aactttgaag
     4861 cttttgttca aaaaaatcaa ttgaatgaag ttcgggtggc tattggcatt aatccagaaa
     4921 acttttcttg gaagttagcc cctgaggaat actttgaaac accggtagct ttagtgactc
     4981 attcagatca gggattaact ggtattagtc atgaaagtca gaattttgta ctgaagcaca
     5041 ttattctaag tgaattttct aaaaaagaac gtccaattct aatcaataac tgggaagcta
     5101 cttactttga ctttcagaga gaaaaactgt tagagttagc agatgaagct aagaaagttg
     5161 gcattgaact ttttgtatta gatgatggtt ggtttggcaa tcgttttgat gataatcgtg
     5221 ctttaggtga ttgggttgtt aatgaggaaa aactgggtgg aagtctagaa agtctgattt
     5281 cagctatcca tgaaagaggt ttgcagtttg gactttggtt agaacccgaa atgatttctg
     5341 tagatagtga tttgtatcgt caacatcctg actgggctat tcaggttcct gattatgagc
     5401 atacttattc tcggaatcaa ttagtactta atcttgccaa tcctcaggta gtagaatact
     5461 tgaaaagtgt cttagatcaa ctcctatctt atcatgagat tgattacatt aaatgggata
     5521 tgaaccgcaa tatcactaag ctagggaatg gattaactta tctagagaca cagatgcaat
     5581 ctcatcagta catgctgggg ctttacgaac tcgtttctta tctgacagag aagcacagcc
     5641 atattctctt tgagtcctgc tctggtggtg gtggacgaaa tgatcttggt atgatgcgct
     5701 atttcccaca agtctgggct agtgataata cagatgctat tgcacgttta ccaattcaat
     5761 acggttcatc ctatctctat ccaaccattt ctatgggggc tcatgtgtca gcagtaccga
     5821 atcatcagat ggggcgaacg acaccattag aaacacgtgg acatgtagca atgatgggaa
     5881 atttgggcta tgagcttgat ttgacaagtt tatcagatga agagaaagct gagattgcta
     5941 atcaggtgaa cttgtataaa gaattacgac cagtagttca gttaggacaa cagtatagac
     6001 taattaatcc tgatactgca tccaatgaag ctgctgtaca atttaattac aaaaatcaaa
     6061 cgattgtaac ctacgttcgc gttttgtcag ttgtagagac catggaaaca actttaaagt
     6121 taaaagattt ggatgaagag ggactatatg aattacagga aaatggcgaa gtttactcag
     6181 gtgcagaact catgtatgcg ggtttaactg ttattttatc ccaaggagat tttttgagta
     6241 aacagtatat ttttagaaga ctataattaa ggtgtataaa tttataaagg aggctttcca
     6301 atgaaatggt ataaaaaaat cggacttctt gcaactacag gtttagcttt ggttgggctc
     6361 ggcgcttgct ccaactatgg taaatctgcg gatggcacag tgaccatcga gtatttcaac
     6421 cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc gtgattttga gaaggaaaac
     6481 cctaagatca aggtcaaagt cgtcaatgta ccaaatgctg gtgaagtatt gaagacacgc
     6541 gttctcgcag gagatgtgcc tgatgtggtc aatatttacc cacagtccat cgaactgcaa
     6601 gaatgggcaa aagcaggtgt ctttgaagat ttgagcaaca aagactacct gaaacgcgtg
     6661 aaaaatggct acgctgaaaa atatgctgta aacgaaaaag tttacaacgt tccttttaca
     6721 gctaatgctt atggaattta ctacaacaaa gataaattcg aagaactggg cttgaaggtt
     6781 cctgaaacct gggatgaatt tgaacagtta gtcaaagata tcgttgctaa aggacaaaca
     6841 ccatttggaa ttgcaggtgc agatgcttgg acactcaatg gttacaatca attagccttt
     6901 gcgacagcaa caggtggagg aaaagaagca aatcaatacc ttcgttattc tcaaccaaat
     6961 gccattaaat tgtcggatcc gattatgaaa gatgatatca aggtcatgga catccttcgc
     7021 atcaatggct ctaagcaaaa gaactgggaa ggtgctggct ataccgatgt tatcggagcc
     7081 ttcgcacgtg gggatgtcct catgacacca aatgggtctt gggcgatcac agcgattaat
     7141 gaacaaaaac cgaactttaa gattgggacc ttcatgattc caggaaaaga aaaaggacaa
     7201 agcttaaccg ttggtgcggg agacttggca tggtctatct cagccaccac caaacatcca
     7261 aaagaagcca atgcctttgt ggaatatatg acccgtccag aagtcatgca aaaatactac
     7321 gatgtggacg gatctccaac agcgatcgaa ggggtcaaac aagcaggaga agattcaccg
     7381 cttgctggta tgaccgaata tgcctttacg gatcgtcact tggtctggtt gcaacaatac
     7441 tggaccagtg aagcagactt ccataccttg accatgaact atgtcttgac cggtgataaa
     7501 caaggcatgg tcaatgattt gaatgccttc tttaacccga tgaaagcgga tgtggattag
     7561 gagtagagag actatgaaaa aagtattaca aaaatattgg gcatgggctt ttgtggtcat
     7621 ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg tttcaaggag ccttttacag
     7681 ttttaccaac tggacaggat tgacttacaa ctacaaattt gtcggcttaa acaactttaa
     7741 gctcctcttc atggatccaa aattcatgaa tgcgattggc tttaccgcaa tcattacgat
     7801 tgccatggtg gttggtgaga ttgcactcgg gatcttcatt gcgcgtgtct tgaactctaa
     7861 aatcaaaggc caaaccttct tccgtgcttg gttcttcttc ccagctgttt tatctggttt
     7921 gacagtggct ttgatcttca agcaagtctt caactacggt cttccagcga ttgggaatgc
     7981 ccttcatatt gaatttctcc aaaccagtct tttagggact aagtggggag caatctttgc
     8041 ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc atcatcatct tcctagctgg
     8101 tttgcaatct attccaactg agattacaga ggcagcaagg attgatggtg cgactagcaa
     8161 gcaagttttc tggaacattg aattgcctta cttgctacca agtgtctcta tagtctttat
     8221 cctagcccta aaaggtgggc tgactgcctt tgaccaagtc tttgccatga ccggtggtgg
     8281 tccaaacaat gccacaacct cacttgggct cttggtttat aactatgcct ttaaaaacaa
     8341 ccaattcggt tatgccaatg ccattgccgt aatcttgttc ttcttaattg tagtgatttc
     8401 gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa gaggagaagc atgatgaaac
     8461 aagatgaaag aaaagccctg attggcaaat acattctatt gattctagga tcggttctgc
     8521 ttttagtgcc gctccttgct accctcttta gttccttcaa acccactaag gatattgtag
     8581 ataatttctt tggctttcca accaacttca catgggacaa ctttagccgt ctcttagctg
     8641 atgggattgg aggctattat tggaactctg tcgtcatcac tgtcttgtct ttacttgcag
     8701 taatgatctt tatccctatg gcagcctact ccatcgctcg caatatgagt aaaagaaaag
     8761 cctttaccat catgtatacc ctcttaatcc tcggaatctt cgtacctttc caagtcatca
     8821 tgattccgat tacggttatg atgagtaaac tcggtttggc taataccttt ggtttgatct
     8881 tgctctactt gacctatgcg attccacaga ccctctttct ctatgttggc tatatcaaaa
     8941 tctcgattcc agaaagtctg gatgaagcag cagagatcga tggggctaat caatttacaa
     9001 cctatttccg catcatcttc ccaatgatga aaccgatgca tgcgacaacc atgatcatca
     9061 atgccctttg gttctggaat gacttcatgt tgccactcct tgtcttgaac cgggattcca
     9121 aaatgtggac tctgcctttg ttccaataca actacgcagg ccaatatttc aacgactacg
     9181 gaccaagctt tgcctcttac gtggtcggca ttatcagtat caccattgtc tatctcttct
     9241 tccaacgcca tatcatttca ggaatgagca acggggcagt gaagtaatac tcaatgaaaa
     9301 tcaaagagca aactaggaag ctagccgcag gttgctcaaa acactgtttt gaggttgtgg
     9361 atgaaactga cgaagtcagt aaccatacct acggtaaggc gacgctgacg tggtttgaat
     9421 ttgattttcg aagagtataa catgaatttg atttacgaag ccagattata tgagacttgg
     9481 cttcaattag aaaaaggaga gtaatgatgc caattcaaaa taaaaccatg ttgattacct
     9541 attctgatag ccttggaaat aatcttaaag acttatatga taatttggaa gagcattttg
     9601 gagatgctat tggaggagtt caccttttac catttttccc atcaacaggt gatcgtggat
     9661 ttgcgccagt tgactacgac gaagtggact cagcttttgg tgattgggag gatgttaagc
     9721 gtttaggtga gagatattat cttatgtttg attttatgat taatcatatt tctcgtcaat
     9781 ccaagtatta taaggactat caagaaaaac atgaagccag tgaatttaaa gatctctttt
     9841 taaactggga taagttttgg ccagaaaacc gtccgacaca gtctgatgta gatttaattt
     9901 acaagcgtaa ggatcgtgca ccaaagcaag agattgtgtt tgaagatggt tcagtggaac
     9961 atttgtggaa tacttttggt gaggagcaga ttgatcttga tgtgaccaaa gaagtaacta
    10021 tggaatttat ccgtaagacc attcagcact tggcaagtaa tgggggtgat ttgattcgtc
    10081 tagatgcctt tgcttatgca gtgaagaaat tgtatactaa tgatttcttt gtggaaccag
    10141 atatttggga tttattggac aaagttcgag atatcgctgc tgagtatggg acagagcttt
    10201 tacctgagat tcatgaacac tattcgattc agtttaaaat agcagaccat gattactatg
    10261 tttatgattt tgctcttcca atggtgacac tttatactct ttacagttcc agaacagagc
    10321 gtttggctaa gtggttaaag atgagcccga tgaagcaatt tacgacgcta gatacccatg
    10381 atgggattgg agtagtagat gtcaaggata tcctgaccga tgaggagatt gactatgctt
    10441 caaatgaact ctataaggtt ggagccaatg tcaaacgtaa gtactctagt gccgagtata
    10501 acaacttaga tatctaccaa atcaattcaa cctactattc agcgcttgga gatgatgatg
    10561 tcaagtattt tctcgctcgt ctaattcaag cttttgcccc aggtattcct caggtttact
    10621 atgtgggtct attagcaggc aagaatgact tgaaattatt agaagaaact aaagaaggtc
    10681 gaaatattaa tcgtcattac tatagcaacg aggaaatagc aaaagaagtg caacgatctg
    10741 ttgtgaaggt ccttctcaat ctattttctt tccgtaaccg ttcagaagcc tttgatctag
    10801 aagggactac tgagatagag acaccaacag ctcagagcat tgtaatcaaa cgtcaaaata
    10861 aagataagtc cgtaacagca gtagcagaaa ttgatttgca aaatcagact tatcgggtaa
    10921 ttgagaatgg agttgaagta acattttgaa gccttgatat ggtggataaa atagggtttt
    10981 tattttggaa aacgtttcct ttgttttcaa attgctaaaa aagtggtaca atataggata
    11041 gcttactatt atctgaatca gctgatttgg agagaaagga ttcattttga aatcaatagg
    11101 ctttattgaa aagctgaagg ggttgtctag taaagagctg attttattgg gaattatcct
    11161 gagtatcttt ttaccctttt atctttttgt agttgtactc tgtttatata ttatcagttt
    11221 gatttttaca ggagacatga aaagtattct tcagaaaatg ggggagcatc cgatgctgct
    11281 tctttttctt agctatagta ctgttatatc cattcttgca caaaattgga tgggtcttgt
    11341 ggcttcagta ggaatgtttc tatttactat tttctttttg cactatcagt cgattttatc
    11401 ccataaattc tttcgattga ttttgcagtt cgtcttgttt ggtagtgtct tgtcagctgc
    11461 ttttgccagt ttagaacatt tccaaattgt gaagaaattt aactatgctt ttctttcacc
    11521 caatatgcag gtgtggcatc agaaccgggc agaagtgacc ttctttaatc ctaattatta
    11581 tggaattatt tgttgtttct gtattatgat tgctttctat ctgtttacaa cgaccaagtt
    11641 gaattggttg aaagtattct gtgtgattgc aggctttgtt aatctctttg gtttgaactt
    11701 tactcaaaat cgaactgcct ttcctgctat tatcgctgga gcaattatct atctctttac
    11761 gactattaaa aactggaagg ccttttggct tagtattggg gtcttcgcga ttggtttgag
    11821 tttcctcttt tctagtgatt tgggagttcg aatgggtact ttagactctt ctatggaaga
    11881 acgcatttct atctgggatg ctgggatggc cttgtttaag caaaatcctt tttggggtga
    11941 agggccattg acctatatgc actcttatcc tcggatacat gctccttatc atgaacatgc
    12001 ccacagtctt tatattgata cgattctgag ttacggaatt gtgggtacca ttttattagt
    12061 tttgtcttct gttgctcctg ttcgcttgat gatggatatg agtcaggagt cggggaaacg
    12121 tccgattatc ggcctttatc tatctttcct tacagtggtt gctgtgcacg gaatttttga
    12181 cttggctctc ttctggattc agtcaggctt tattttcttg ctagttatgt gcagtattcc
    12241 attggagcat cgaatgttgg tatcggacat gacggattaa gttttataag tttgaaatct
    12301 tctaccttgg gtaggagatt tttttatacg atgggcatgt cgtgcatctg aggtgtaagt
    12361 cctctgtagg gatccactgc cggtgaatac aatagcgctc cccaagcctg actatcgtga
    12421 ggtagcggat taaaatggtc tggggataga tcgttttaag tctgacgcag gaaataagaa
    12481 ttgtcagaga aagcaatagt gaaatcgtag gctatgaata gaaacgtgat agcgaggagc
    12541 atatagtgga taaggtagcg agaaatttta aagtataaaa gatagtctta atctatatat
    12601 gtaaatcaca aaagtaattg aattcggaat aaggttggtg tgaaaagaca tagtaaactg
    12661 aatcttgaat actagaatga tacttctaca atattgttat aatttaattt gaattccaaa
    12721 atcacattgt tccgtccgta tttcatttta ctgtatgtct tcctaaactc caaagtttct
    12781 gcgtcaaatt tcctattttc actgtagtct ttgacacttc gaacgacaat ttgaatcata
    12841 tattcaaaaa aaaatgaaaa atttgtgcca acaagcctaa atattctgaa aatttgtttg
    12901 atttttaatg gataatgtga tataatggtt gtcaatctat aattcacata aacagaggag
    12961 tagaaaatga aaaaaaatcg tgtatttgct acagcaggtc ttgttttatt agcagcaggt
    13021 gtacttgcag catgcagttc ttcaaaatca tctgactcat cagcccctaa agcttatggc
    13081 tatgtttata cagcagaccc agaaaccttg gactacctga tttcaagtaa aaatagtaca
    13141 acagtagtga cttcaaatgg gattgatggt ttattcacta acgataatta cggtaatctt
    13201 gctcctgcag ttgcagagga ttgggaagtc tctaaggatg gtttgaccta cacttataag
    13261 attcgtaaag gggttaaatg gtttacctct gatggagaag aatatgcaga ggtgacggct
    13321 aaagatttcg tgaacggttt aaaacacgca gcagataaaa aatcagaagc tatgtattta
    13381 gctgaaaatt cggttaaagg cttggcagat tatctatcag gaacttcaac agatttttca
    13441 acagttggtg tcaaggcggt tgatgattat acgttacaat acactttgaa ccagcctgaa
    13501 ccgttctgga actctaagtt gacctattct attttctggc ctctgaatga agaattcgaa
    13561 acatcaaaag gaagcgattt tgctaaacca acagatccga catccttgct ttataatggt
    13621 ccattcttgt tgaaagggtt gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa
    13681 tattgggata aagaaaatgt ccacctagat actatcaatc tagcttacta tgatggatca
    13741 gatcaggagt cgctagagcg taacttcact agtggagctt atagttatgc ccgtctttac
    13801 cctaccagct ccaactattc taaggttgca gaagaataca aggacaatat ctattacaca
    13861 caatcaggct ctgggattgc tggtctgggt gtgaatattg atcgccaaag ttacaactat
    13921 acttctaaaa ctacagattc agagaaagta gctactaaga aggcattgct taacaaagat
    13981 ttccgtcaag ccttgaattt tgctcttgat cgctcagctt actcagctca aatcaatggt
    14041 aaagatggag cagctttagc agttcgtaat ttatttgtaa aaccagactt tgtttcagct
    14101 ggtgagaaga cctttggtga tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg
    14161 aaaggtgtga atttagctga tgggcaggat ggtttattca atgctgacaa ggccaaggca
    14221 gagtttgcga aagctaagaa agctttagaa gcagacggcg ttcagtttcc tattcatctg
    14281 gacgttccag tagaccaagc atcaaaaaac tacatatctc gtattcagtc ctttaaacaa
    14341 tctgtagaaa cagttcttgg tgttgaaaat gtcgttgttg atattcaaca aatgacaagt
    14401 gatgaattcc ttaatattac ttactatgct gccaatgctt catctgagga ttgggatgta
    14461 tcgggaggag tttcatgggg gccagactat caagacccat ctacttacct ggatatttta
    14521 aaaacaacta gcagtgaaac tacaaaaaca tatttaggat ttgataatcc aaatagccct
    14581 tcagtagttc aagttggttt gaaagaatac gataaattag ttgatgaagc tgccaaagag
    14641 acaagcgact tgaatgtccg ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat
    14701 agttcactct ttattcctgc tatggcttct tctggtgcag caccagtgct ttcacgaatt
    14761 gttccattta ctggagcttc tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa
    14821 tatttgaaat tacaagataa agtggtgact aaggaagagt atgaaaaagc tcgtgaaaaa
    14881 tggttgaaag aaaaagctga atcaaatgag aaagctcaaa aagaattggc aagtcatgtg
    14941 aagtaaataa tttctaatag aactttctct ccatgaggag aaggttcttt tgggattttt
    15001 aaaggaaata atatgaaaaa atatattttt atgcgtgttt tgcggtcatt ggtttcgatt
    15061 ttcttagtaa cgactttgac ctacacgatt atctatacct tggttcctcg aaaattgatt
    15121 ttcaagcagg atcctaacta taataaaatt gcgacaacgg ctgataaacg tgataactat
    15181 gaaaatactg tgtttgagcg tatgggctac attgagtatt acgatactaa agagttgcaa
    15241 gaaaaggcaa gtagcatgga ttcttctgta acagtagaag caaatgcgac caataaagct
    15301 atttatgaaa agtacatcaa tcaattaggt catggttgga ctttgggaga atttactgaa
    15361 agtggtcaat tctatgctac tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat
    15421 gctaacttga ttgacattga ccatacaaat aaaatccaag accctgaaaa tccagacttg
    15481 aaacgctacc ttcgttttga aaatgatcca gctatcggat ggtcattggt cggttcagga
    15541 actaaacata aatatctctt gtactttaac agtcagttcc catttgttca tcaaaacttt
    15601 gtgaacttga atttaggtga ctcttaccca acctatgcta atacaccagt tcttcaggtt
    15661 attactcaag gtcaaggaca aaccaaaact gcccaagttc agttcccaac aggtaagaaa
    15721 acgtcttctg taaatattta ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt
    15781 gaagtagcta gctatgggaa agatgatcct tatacagcga ctgaaagtaa ttaccaatat
    15841 ccatctatga ttgtcagctc tgctattact ggtttgattg gtttggttct tgcctatgct
    15901 cttgccgtgc cacttggttc agccatggct cgtttcaaga acacttggat tgatagcctc
    15961 tcaacaggga ctttgacctt cttgcttgct cttccaacga ttgccttggt ttacatcgtt
    16021 cgattgattg gatcatctat tgcccttcca gattcattcc ctatcttggg agctggagat
    16081 tggcgttctt acgttttacc agcagtcatc cttggtttgt tgggtgctcc tgttacagcc
    16141 atttggattc gtcgttacat gattgacttg caatctcaag actttgttcg tttcgctcgt
    16201 gcaaaaggtt tgtctgaaaa agaaatttca aacaaacaca tctttaaaaa tgccatggtt
    16261 ccgctggttt caggaattcc tggtgccatt attggggtta tcggtggtgc aacccttact
    16321 gaaacagtct tcgccttccc aggtatgggt aaaatgttga ttgactctgt aaaagcatct
    16381 aataactcta tggtcgttgg tcttgtcttc atctttacat gtatttctat cttctcacgt
    16441 cttttgggag atatttggat gactattatt gacccacgta ttaaattgac tgagaaagga
    16501 ggcaaataat gtctacaatc gataaagaaa aatttcagtt tgtaaaacgt gacgattttg
    16561 cctctgaaac tattgatgcg ccagcatatt cttactggaa atcagtgttt aaacaattta
    16621 tgaagaaaaa atcaactgta gtcatgttgg gaatcttggt agccatcatt ttgataagtt
    16681 tcatctaccc aatgttttct aagtttgatt tcaatgatgt cagcaaggta aacgacttta
    16741 gtgttcgtta tatcaagcca aatgcggagc attggttcgg tactgacagt aacggtaaat
    16801 cgctctttga cggtgtctgg ttcggagctc gtaactccat cctcatttct gtgattgcga
    16861 cagtgattaa cgtggttatc ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag
    16921 ttgaccgtgt catgatggaa gtttacaacg tcatctcaaa catcccacct cttttgattg
    16981 ttattgtctt gacttactca atcggagctg gattctggaa tctgattttt gccatgagcg
    17041 taacaacatg gattggtatt gccttcatga tccgtgtgca aatcttgcgc tatcgtgact
    17101 tggaatacaa cttggcgtca cgtactttgg gaacaccaac cttgaagatt gttgccaaaa
    17161 atatcatgcc tcaattggta tctgttattg tgacaaccat gactcaaatg cttccaagct
    17221 ttatctcata cgaagccttc ttgtctttct tcggtcttgg attaccgatt acagtgccaa
    17281 gtttgggtcg tttgatttcg gattattcac aaaacgtaac aaccaatgct tacttgttct
    17341 ggattccatt gacaaccctt gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact
    17401 tagcggatgc tagtgatcca cgtacacata gataggagta gaaatgacaa aagaaaaaaa
    17461 tgtaattttg actgctcgcg atattgtcgt ggaatttgac gttcgtgaca aagtattgac
    17521 agccattcgc ggcgtttccc ttgaactagt cgaaggagaa gtattagcct tggtaggtga
    17581 gtcaggatca ggtaaatctg ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg
    17641 tcgtattgcc caaggtagta ttgactaccg tggtcaggac ttgacagctt tatcttctca
    17701 caaggattgg gaacaaattc gtggtgctaa gattgcgact atcttccagg acccaatgac
    17761 tagtttggac cccattaaaa caattggtag tcagattaca gaagttattg taaaacacca
    17821 aggaaaaaca gctaaagaag cgaaagaatt ggccattgac tacatgaata aggttggcat
    17881 tccagacgca gatagacgtt ttaatgaata cccattccaa tattctggag gaatgcgtca
    17941 acgtatcgtt attgcgattg cccttgcctg ccgacctgat gtcttgatct gtgatgagcc
    18001 aacaactgcc ttggatgtaa ctattcaagc tcagattatt gatttgctaa aatctttaca
    18061 aaacgagtat catttcacaa caatctttat tacccacgac cttggtgtgg tggcaagtat
    18121 tgcggataag gtagcggtta tgtatgcagg agaaatcgtt gagtatggaa cggttgagga
    18181 agtcttctat gacccttgcc atccatatac atggagtctc ttgtctagct tgcctcagct
    18241 tgctgatgat aaaggggatc tttactcaat cccaggaaca cctccgtcac tttatactga
    18301 cctgaaaggg gatgcttttg ccttgcgttc tgactacgca atgcagattg acttcgaaca
    18361 aaaagctcct caattctcag tatcagagac acattgggct aaaacttggc ttcttcatga
    18421 ggatgctcca aaagtagaaa aaccagctgt gattgcaaat ctccatgata agatccgtga
    18481 aaaaatggga tttgcccatc tggctgacta ggaggaagga aatgtctgaa aaattagtag
    18541 aaattaaaga tttagaaatt tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa
    18601 atgctaactt ctttatcaac aagggagaaa ctttctcgct tgtaggtgag tccggtagtg
    18661 ggaaaacaac tattggtcgt gctatcatcg gtctaaatga tacaagtaat ggagatatca
    18721 tttttgatgg tcaaaagatt aatggtaaga aatcgcgtga acaagctgcg gaattgattc
    18781 gtcgaatcca gatgattttc caagaccctg ccgcaagttt gaatgaacgt gcgactgttg
    18841 attatattat ttctgaaggt ctttacaatc accgtttatt taaggatgaa gaagaacgta
    18901 aagagaaagt tcaaaatatt atccgtgaag taggtcttct tgctgagcac ttgactcgtt
    18961 accctcatga attctcaggc ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca
    19021 tgcaaccaga ctttgttatt gcagatgagc caatttcagc cttggacgtt tctgtacgtg
    19081 cccaagtctt gaacttgctc aaaaaattcc aaaaagagct cggcctgacc tatctcttca
    19141 tcgcccatga cttgtcggtt gttcgcttta tttcagatcg tatcgcagtt atttacaagg
    19201 gtgttattgt agaggttgca gaaacagaag aattgtttaa caatccaatt cacccatata
    19261 ctcaagcctt gctttcagcg gtaccaatcc cagatccaat cttggaacgt aagaaggtct
    19321 tgaaggttta cgatccaagt caacacgact atgagactga taagccatct atggtagaaa
    19381 tccgtccagg tcactatgtt tgggcgaacc aagccgaatt ggcacgttat caaaaaggac
    19441 taaactagta atggttttat aatttccatg tcaattttta tggaaattag gctctttgtc
    19501 aactgtagtg ggttgaagtc agctaagctc gagaaaggac aaatttcgtc ctttcttttt
    19561 tgatgttcaa agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg
    19621 cattgcgctt gataagtttg atgagattat tggtcgcttc cagtttggca ttagaatagt
    19681 gtagttgaag ggcgttgata atcttttctt tatctttgag gaaggtttta aagacagtct
    19741 gaaaaatagg atgaacctgc ttaagattgt cctcgataag ttcgaaaaat ttctctggtt
    19801 ccttattctg gaagtgaaaa agcaagagct gatagagctg atagtggtgt ttcaagtctt
    19861 ccgaataact caaaagcttg tttaaaatct ctttattggt taagtgcata cgaaaagtag
    19921 gacgataaaa acgtttatca ctcagtttac ggctatcctg ttgtatgagc ttccagtagt
    19981 gcttgatagc cttgtattca tgggattttc gatgaaactg attcatgatt tggacacgca
    20041 cacgactcat agcacggcta agatgttgta caatgtgaaa gcgatcaaga acgattttag
    20101 cattcgggag tgaaacagtc taggagactg tttcagcctg agcctagaaa tttgaaagcg
    20161 aagctgttta gccaagtcat agtaagggct aaacatatcc atagtaatga ttttgacgcg
    20221 acatcggacg gctctatcat atttaagaaa gtgatctcgg atgacagctt gtgttctacc
    20281 ttcaagaaca gtgatgatat cgagcttttc aaaattttgc gcaataaagc tcatctccat
    20341 ctcccgattg aaacagtcac tccccggact gtttcaacgt cccaagacat aatcttaggc
    20401 agatttctaa aattacactc aaagtgaaag tcattgagct tgcgaatgac agttgaagtt
    20461 gaaatggcca gctgatgggc aatatcagtc atagaaatct tttcaattaa cttttgagca
    20521 atcttttggt tgatgatacg agggatttgg tgattcttct tgacgataga agtttcagcg
    20581 accatcattt ttgaacagtg atagcactta aagcgacgct ttctaaggag aattctagta
    20641 ggcataccag ttgtctcaag gtaaggaatt ttatagggtc tttaatgtct agtaattttg
    20701 tgataaaatg taattgttct atatgattct ttctaatgag ttgttttgtc gcttttcatt
    20761 ataggtcata tgggactttt tttctacaca aaaataggct ccataatatc tataggggat
    20821 ttacccacta caaatattat agagccgaaa aaggctgaga tctggtgtct cagtctttta
    20881 tttcttgcgt tttgcaaaat ctacaaatct aaatttttct aacttatggc gactttcggt
    20941 aaactgaaat tggcgtccgt cttggagata gacttttgat ttaatcgaaa cgacataagg
    21001 gtctttgcca atgtccatga gaatcttgtc tcggtcgctt gagtggtcaa tggtgatttc
    21061 cttctgagca taatcaataa ggagtttgag gccattttct atataagaat agatagactg
    21121 ctcagcaatt tggcgagtga gatttggaat tagttccata tccagatagt ctgtatccag
    21181 aacggatacc agatcatcca ccacacgctg gcggaccacc ttccaaacca tccgaaactc
    21241 tgggaaaccg gttatcagcg aggatttttt atcaataata atcttgtcca gactgaccac
    21301 gttggtttta gagcgcagtc caagttcttt aactagttct tggtagctgg ttaggttgga
    21361 tacagggaaa ttgacggttt cttctttgac gacttgagaa ccttgccctc ttatcttttt
    21421 gatcaatcct tcctcttgga ggagagacag ggcctttcgg acggtatcac gactcacttg
    21481 atattgctcc ataaggtcgt gctcgctagg aaggaaatct ccgacagcgt aagtctcgtt
    21541 ttgaatggtt tcttggattt gcttaaataa ttgttggtat ttcttcattt tgcctgctta
    21601 aataggtttt tagtctagtt taatgaacac ctgtatctat tttaccatac aagtgctaga
    21661 aaatttacaa aaaaacaccc tttttatacc aaacaagttg tagacaagtt tggtatcgtt
    21721 tacaatatac ttatcaaatc aaacttgctt tgacaagtat aaggagaatc aaatgggaaa
    21781 atttgaacaa gaagccaaag atctgcttca ggcaattgga ggcaaagaaa atgtgactgc
    21841 cgtaactcac tgtgcgacac ggatgcgctt tgttttaaga gatgataaga aggctaatgt
    21901 taaagctatc gagtcaattc cagctgttaa aggaactttt acaaatgcag gtcaatttca
    21961 ggtaatcatt ggaaatgacg tgcccatctt ttataatgat tttacagccg tttcaggtat
    22021 tgagggtgtt tccaaagaag caaccaagtc tgcagctaag agtaatcaaa acgtggttca
    22081 aggtgttatg accactctgg cggaaatctt tactccgatt attccagcct tgattgttgg
    22141 tggattgatc ctcggtttcc gtaatgtctt ggaaggtgtc cattggtcga tgttggatgg
    22201 caagaccatc acagaatcct ctcagttttg ggcaggggtt aatcacttcc tctggttgcc
    22261 tggtgaagct atcttccagt tcttaccagt agggattact tggtctgttt ctcgtaagat
    22321 gggaaccagc caaattttgg ggattgttct cggaatctgt ttggtatcgc ctcagttgct
    22381 caatgcctat gcggttgctt caacgccagc agctgatatc gcggcaaact gggtttggaa
    22441 ttttggttat tttactgtta atcgtattgg ttaccaagcc caagttatcc cagccttgct
    22501 tgcaggtttg agtctgtctt atcttgaaat tttctggcgc aaacatatcc cagaagtcat
    22561 ttccatgatt tttgtacctt tcttgtcatt gattccagcc ttgattttgg ctcatactgt
    22621 tttgggacca atcggttgga caattggaca aggactttca tcagttgtct tggcaggttt
    22681 aactggtcca gttaaatggc tcttcggtgc aatttttggt gccctctacg ctccatttgt
    22741 catcacaggt ctgcaccata tgaccaatgc cattgataca caattgattg cggatgctgg
    22801 tggcactgcc ctatggccaa tgattgctct ttctaatatt gctcaaggct cagccgtgtt
    22861 tgcctattat ttcatgcatc gccatgatga gcgtgaggct caggtttcac ttcctgcaac
    22921 catttcagcc tatctcggtg ttacagaacc agctcttttt ggggttaacg taaaatatat
    22981 ttatccattt gttgctggga tgactggttc agcccttgca ggcatgttat ccgttacttt
    23041 taatgtaact gcggcttcta ttggtatcgg tggtttgcca ggtattctct ctattcaacc
    23101 tcaatacatg ctgccatttg caggaactat gctagttgcg attgttgttc caatgctctt
    23161 gactttcttc ttccgcaagg ctggtctctt tacaaaaaca gagggcgata cgaacttgca
    23221 ggcagaattc gttgctcaag aagaagcaga atttgtgagc catgaactag tagaacttac
    23281 ttcggtagaa attatcagcc cactaactgg ccaagtgaaa gaattgagtc aagcgacgga
    23341 tcctgttttt gcatcaggtg tcatggggca aggtctggtc attgaaccaa gccaaggtga
    23401 gttgatctct ccagttaatg gaacagtgac ggttcttttc cctaccaagc atgccatcgg
    23461 cattgtctct gacgagggag ttgaattgct catccacatc ggtatggata cagtaggtct
    23521 tgatggcaaa ggttttgaaa gtcttgtagt ccaaggagat cacgttacag ttggtcagca
    23581 actgattcgt tttgatatgg atgtcattaa ggctgcaggt ctggtgacag aaactcctgt
    23641 tatcatcacc aaccaagatg cttatacagc gactattact ggaacttatc cgacaacgat
    23701 ccaagctgga gcatctctca tggtcgctac acgaatctaa tactcttcga aaatctcttc
    23761 aaaccacgtc agctctatct gcaacctcaa aatagtgttt tgagcaacct gtggctagct
    23821 tcctagtttg ttctttgatt ttcattgagt ataattgaaa tagcacaaat agggacggaa
    23881 tactgcttcc tcccttttat cagaaaagga gaaacagatg acacttgata aaggaaaagt
    23941 agtctatcaa atctatccaa aatcttacaa agacaccact gaaaacggta ttggggattt
    24001 ccgtgggatt atcgaaaaaa ttccctattt agccaaacta ggtgtggata tggtctggct
    24061 caatccattc tatccaagcc ctcaacggga taatggttac gatatttcag attatatggc
    24121 agtggatcct ctttttggtg atatggctga ttttgaggaa atggtgtgtg tcggtaaaga
    24181 gcacaagatt gactttatgc tggacatggt acttaatcat tgttcgacag agcatgaatg
    24241 gtttcagaaa gccctagctg gtgataagta ttatcaagac tttttcttca tccaagacca
    24301 accaacagat tggcagtcta agtttggtgg ttctgcatgg gcgcctttcg gggatactgg
    24361 gaaatactat cttcacctat ttgatgagac ccaggctgac cttaactggc gcaatcccaa
    24421 tgtccgtaag gagcttttca aggttgttaa tttctggcgc gacaagggtg tcaaaggttt
    24481 tcgatttgat gtgatcaatt tgatcggtaa ggacgaggtt tcagtggact gtcctgaaaa
    24541 tgaagggaag ccagcttata cagacaaacc tatcgttcat aactatttgc gtatgatgaa
    24601 ccaagccact tttggatctg acgatagctt tatgacagtt ggggaaatgt cttctaccac
    24661 catggaaaac tgtgtccttt attcgtcgcc tgatcgtcag gaattatcca tgacctttaa
    24721 ttttcatcac ctcaaggtgg actataagga tggacaaaag tggaccttgg ctccctttga
    24781 ttttgaagag ttgaagagtc tttaccatag ttggggtaag gaaatgagtg ataaagacgg
    24841 ttggagtgcc ctcttttgga acaatcacga tcaaccacgt gccttgaacc gttttgtcga
    24901 tattcaaaac ttccgcaagg aaggagccac catgctagca gccagcattc acctgtcacg
    24961 tgggacacct tatatctaca tgggtgagga aatcgggatg attgacccag actatgattc
    25021 tatggctgat tatgtggatg tcgaatcgct taatgcctat cagatgctct tagaagaagg
    25081 aaagagtcag caagaagcct tccagattat tcaagctaag tcgcgtgata attcacgcat
    25141 tcccatgcag tgggatgctt cggaaaatgc aggattttca acaggcactc catggttgaa
    25201 agctggtaaa tcctataaag atatcaatgt agaaaatgaa atcaaaggtc cgattttcac
    25261 cttctatcaa gacttgattc gactgcgtaa ggaaatgcca atcatttcag aaggaaatta
    25321 caaaccagcc tttgaagata gcaaacaagt ctacgctttt gaacgccagt ttgaggatca
    25381 aaagttacta gtgctcaata acttttatgc taaagaagtg gaaatcgact tgccagcagt
    25441 ctaccaaaat ggacagattt tgatatcaaa ctatgaagat gcagaagtgt ctgagaaaat
    25501 tctactcaaa ccctatcaaa cactggctat ttatgtaaat taatactctt cgaaaatctc
    25561 ttcaaaccgt gtcagtttta tctgcaacct caaagcggtg ctttgagcaa cctgtggcta
    25621 gcttcctagt ttgctctttg attttcattg agtataaact tagcaaggag acctcttttt
    25681 cagaaaagca gggttctttt tgctgtctat tccatccttg aaagtgtaga acaaactggt
    25741 cagggtggct agtttgtggt ataatgaaag ggattcaaaa agaaacagga gaaaaatgat
    25801 ggatttactt ttagcaattg tattgattgt gctagctttt ctaggaggag ctcttggagg
    25861 aatgtacttg gttcgtaagc aaatcgaaaa agaatttgct gacaacccac gtttgaatgc
    25921 tgaagcagtt cgtactcttt tgagtgcaaa tggtcaaaaa ccaagcgaag ctaaggtaca
    25981 acaagtttac caccaaatca tccgccaaca aaaggcagcc cttgctaaca ataaaaagaa
    26041 aaaataaata aggaaaagtc tgggatgaaa gttccagact tctcactatg ttggttatgg
    26101 tttagggatg agactttttc cttgcattct attgatattt gattatgatt aagagagagg
    26161 tagttgacat tctatcaagc tgtcggtcag ttcgttcagt acaaggaatc ataatgaacg
    26221 atcaatcaga aaaaagacta gaaagaagac tgtatggata atcgaccaat tggttttttg
    26281 gattcgggtg tcgggggctt gaccgttgtg cgcgagctca tgcgccagct tccccatgaa
    26341 gaaatcgtct atattggaga ttcggcgcgg gcgccctatg gcccccgtcc tgctgagcaa
    26401 attcgtgaat atacttggca gctggtcaac tttctcttga ccaaggatgt caaaatgatt
    26461 gtcattgctt gtaacactgc gactgcggtc gtctgggaag aaatcaaggc tcaactagat
    26521 attcctgtct tgggtgtaat tttgccagga gcttcggcag ccatcaagtc cagtcaaggt
    26581 gggaaaatcg gagtgattgg aacgcccatg acggtacaat cagacatata ccgtcagaaa
    26641 atccatgatc tggatcccga cttacaggtg gagagcttgg cctgtcccaa gtttgctccc
    26701 ttggttgagt caggtgccct gtcaaccagt gttaccaaga aggtggtcta tgaaaccctg
    26761 cgtcccttgg ttggaaaggt ggatagcctg attttgggct gtactcatta tccactcctt
    26821 cgccctatta tccaaaatgt gatggggcca aaggttcagc tcatcgatag tggggcagag
    26881 tgcgtacggg atatctcagt cttactcaat tattttgaaa tcaatcgtgg tcgcgatgct
    26941 ggaccactcc atcaccgttt ttacacaaca gccagtagcc aaagttttgc acaaattggt
    27001 gaagaatggc tggaaaaaga gattcatgtg gagcatgtag aattatgaca aataaaattt
    27061 atgaatataa ggatgaccag gactggtatg ttgggtctta tagtattttt ggtggcgtta
    27121 acagtttgag cgactatcag acagattttc ctctgtttga attctccaaa atatttggag
    27181 atgaagagta tggtttcccg ctttcagtta ctgttttacg ctatggttct acctaccgtt
    27241 tgttctcctt tgtggtagat atgcttaatc aagaaatggg acgaaacttg gaagttattc
    27301 aacgtcatgg ggccctgctc ttggttgaaa atgggcaact cttgtatgta gaattgccta
    27361 aagaaggggt caatgttcat gatttctttg agacaagcaa ggtcagagaa accttgttga
    27421 ttgcgactcg taacgaaggc aaaaccaagg aattccgagc tatctttgat aagttaggct
    27481 acgatgtgga aaatcttaat gactaccctg acctgcctga agtagcagaa acaggtatga
    27541 cctttgaaga aaatgcccgc cttaaggcag aaaccatttc tcaattaacg ggcaagatgg
    27601 ttttggcaga tgattctggt ctcaaagtcg atgtccttgg tggcttacca ggcgtctggt
    27661 cagctcgttt cgcaggtgtg ggagcaactg accgtgaaaa taatgccaaa ctcttgcacg
    27721 aattggccat ggtctttgaa ctcaaggacc gctcggctca gttccacaca accctagtcg
    27781 tagccagccc aaataaggaa agtttagttg ttgaagcaga ctggtcaggt tatattaact
    27841 ttgaacctaa gggtgaaaat ggctttggct atgatcccct cttccttgta ggagagacag
    27901 gtgagtcatc agctgaatta accctggaag aaaaaaatag tcaatctcac cgtgccttag
    27961 ccgttaagaa acttttggag gtatttccat catggcaaag caaaccatca ttgtaatgag
    28021 cgattcccat ggcgatagct tgattgtgga agaagtccgt gatcgctatg tgggcaaagt
    28081 cgatgccgtt tttcataacg gcgattctga actacgtccg gattctccac tttgggaggg
    28141 catccgcgtt gttaaaggga acatggactt ctacgccggc tacccagaac gtctggtgac
    28201 tgagcttggt tcgaccaaga ttatccaaac tcatggtcac ttgtttgaca tcaatttcaa
    28261 ctttcaaaag ttggactact gggctcagga ggaagaggcc gctatctgcc tctatggtca
    28321 cttgcatgtg ccaagtgctt ggttggaagg caagatcctc tttctaaatc caggctctat
    28381 cagtcaacca cgaggtacca tcagagaatg tctctatgct cgtgtggaga ttgatgatag
    28441 ttacttcaaa gtggactttt tgacacgaga tcacgaggtg tatccaggtt tgtccaagga
    28501 gtttagccga tgattgccaa ggagtttgag actttcttgt tggggcagga ggaaactttt
    28561 ttgacccctg ctaaaaatct agctgtgttg attgatactc acaatgcgga tcatgcgacc
    28621 ctcttgctca gtcagatgac ctatacccgt gttcccgttg tgacagatga aaaacagttt
    28681 gttgggacga ttggactcag agatattatg gcttatcaga tggagcatga cttgagccaa
    28741 gaaatcatgg cggatacgga tatcgttcat atgacaaaaa cggacgtagc ggttgttttg
    28801 cctgatttca ccattacgga ggtcttgcac aagctagtag atgagtcctt cttaccggtt
    28861 gtggatgcag agggtatttt ccaagggatt attacgcgca agtccatcct caaggccgtt
    28921 aatgccctct tgcatgactt tagtaaggaa tatgagattc gatgccaatg agagacagga
    28981 tttcagcctt tttagaggaa aagcagggct tgtctgtcaa ttccaagcag tcctataagt
    29041 atgatttgga gcaattttta gacatggtag gtgagcggat ttctgagacc agtctcaaga
    29101 tttaccaagc ccagctagcc aatctaaaaa tcagcgccca gaagcgaaag atttcggcct
    29161 gtaaccaatt tctatacttt ctctatcaaa aaggagaggt ggacagcttt taccgcttgg
    29221 aattagccaa acaagctgaa aagaagacgg aaaagccaga gattctatac ctagactctt
    29281 tttggcagga aagcgaccat ccagagggcc gcttgctagc gctcttaatc ctagaaatgg
    29341 ggctcttgcc cagtgagatt ttagccatca aggttgcgga catcaatctg gattttcagg
    29401 tgttgcgaat cagcaaggct tccaaacgga ggattgtcac cattcccacg gccttgcttt
    29461 cagaattgga acccttgatg gggcagacct atctttttga aagaggaggg aaaccctatt
    29521 ctcgtcagtg ggcctttcgt cagttagaat cttttgtcaa ggagaaaggt tttccatcct
    29581 tatcagctca agtcttacgt gaacagttta ttctaagaca aatagaaaac aaggtcgatt
    29641 tgtacgaaat tgcaaaaaaa ttaggattaa aaacagtcct gaccttagaa aaatatagat
    29701 aatggatatt aaattaaaag attttgaagg acccctggac ttactcttgc atctggtttc
    29761 taagtaccag atggatatct acgatgtgcc cattacggaa gtcatcgaac agtatctagc
    29821 ctatgtttca accctgcagg ccatgcgtct ggaagtgacg ggtgagtaca tggtcatggc
    29881 tagtcagctc atgctgatta agagtcgtaa actccttccg aaggtagcag aagtgacaga
    29941 cttgggggat gacctggagc aggacctcct ctctcaaatc gaagaatatc gcaagttcaa
    30001 gctcttgggt gagcacttgg aagccaagca ccaagaacgg gcccagtatt attccaaagc
    30061 gccgacagag ttgatttacg aagatgcgga gcttgtgcat gacaagacga ccattgacct
    30121 ctttttggct ttttcaaata tactagccaa gaaaaaagag gagtttgcac aaaatcacac
    30181 gacgatcttg cgggatgagt ataagattga ggacatgatg attatcgtga aagagtcctt
    30241 gattggacga gatcaattgc gcttgcagga tttgttcaag gaagcccaga atgtccaaga
    30301 ggtcatcacc ctctttttgg caaccctaga gttaatcaaa acccaggagc tgatcctcgt
    30361 gcaagaggag agttttggag atatctatct catggaaaag aaggaagaaa gtcaagtgcc
    30421 tcaaagctag acttgataga gaggaaagat gagtacttta gcaaaaatag aagcgctctt
    30481 gtttgtagcg ggtgaagatg ggattcgggt ccgccagtta gctgaactcc tctctctgcc
    30541 accgacaggc atccagcaaa gtttaggaaa attagcccag aagtatgaaa aggacccaga
    30601 ttccagtttg gctttgattg agacaagtgg tgcttataga ttggtgacca agcctcaatt
    30661 tgcagagatt ttgaaggaat actctaaggc gcctatcaac cagagcttgt ctcgggctgc
    30721 ccttgagacc ttgtccatta ttgcctacaa acagccgatt acgcggatag aaattgatgc
    30781 catccgtggg gttaactcga gtggagcctt ggcaaagttg caggcttttg acctgataaa
    30841 ggaagacggg aaaaaggaag tattggggcg ccccaacctc tatgtgacta cggattattt
    30901 cctagattac atggggataa accatttaga agaattacca gtgattgatg agcttgagat
    30961 tcaagcccaa gaaagccaat tatttggtga aaggatagaa gaagatgaga atcaataagt
    31021 atattgctca cgcaggtgtg gccagtagga gaaaagcaga agagctgatt aagcaaggct
    31081 tggtgacggt taacggccaa gtggtgcgtg aactggcaac cactatcaag tcaggcgaca
    31141 aggtcgaagt tgaaggtcaa cctatctaca acgaagaaaa ggtctactat ctgcttaaca
    31201 aaccacgtgg tgtgatttcc agtgtgacag atgataaggg tcgcaagacg gttgtcgacc
    31261 tcttgcccaa tgtcaaagaa cgtatttacc ctgtgggtcg tttggactgg gatacatcag
    31321 gtgtcttgat tttgaccaat gatggggact ttacagacga gatgattcac cctcgtaatg
    31381 agattgacaa ggtttatgtc gcgcgtgtta aaggtgtggc caataaggac aatcttcgcc
    31441 ccttgacccg tggtcttgag attgatggta agaaaaccaa gccagctgtt tatgaaattc
    31501 tcaaagtgga cccagtcaaa aatcgctctg tggtgcagtt gaccatccat gaagggcgta
    31561 accatcaagt taaaaagatg tttgaagctg ttggtctcca agtagataag ttgtctcgga
    31621 ctcgtttcgg acacctagac ttgacaggac tccgtccagg agaatctcgt cgtcttaata
    31681 aaaaagaaat cagccaacta cacaccatgg ctgtaactaa gaaataatga aacgaatttt
    31741 aatagcgcct gtgcgctttt accaacgttt tatctcacca gtctttccac cctcttgtcg
    31801 ctttgatctg acttgttcca actacatgat tcaggctatt gaaaaacatg gttttaaggg
    31861 ggtattgatg ggcttggctc ggattttacg ttgtcatccc tggtcgaaaa caggtaagga
    31921 ccccgttcca gaccgctttt cccttaaacg aaatcaagaa ggggaatgag gttgggtaaa
    31981 tagatttcaa aatgataaaa acgcatccta tcaagtttga gtgaacttga taggatgcgt
    32041 tttagaatgt caaaatttta tactcttcga aaatctcttc aaaccgcgtc agctttcatc
    32101 tgcaacctca aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat
    32161 tttcattgag tattaaattg agtttgaagt ggcttatttc aaagcttttt gtatgtcttc
    32221 aatcatgagt tttgttgatt caagtccgcc tccgcttaga taccagaggt ctggtgttag
    32281 ttggataatc ttaccatttt tagcagcagg tgtttcagcg ataagggcat tttctaggac
    32341 accgtcgttg ctagagttgt ccccaccgat ggcaagggta cggttgatga caaagaggat
    32401 gtcagggttg atttctttga cactttcaaa gctgatttct tgtccgtggc gtgagtcttc
    32461 aaattttgta tcagttggtt tgaatttcaa ggtttggtac aagaaagaga aacgagattt
    32521 ggcaccaaag gctgccattt ttccttcatt aaggaggatc gcaagggctt ttttgtcaga
    32581 gctttcattt ttagtagcga cttcttggat gctcttgtct agcttggcca attcttcctt
    32641 ggctttctgt gtaccagttt cgccgaaggc acttgctaag gattcgatat tagccttggt
    32701 agaagtccag tagtcgtcct tgcttgcttg gaagagaacg gttggggcga tttctttgaa
    32761 tttgtctacg aatttttgtg tacgtggtga agcgataatc aaatcaggct caagggcggc
    32821 gatagcttct aaatcaggtt ctttcataga accaacattt ttgacagttc ccactaggtc
    32881 ttttagataa gtcggaacag tttttgtagg cattccgacg atattttttt caaatcctaa
    32941 agcgcgaata gtatccgcag cgccgaggtc aaaggtcaca atcttttcag gaactttgga
    33001 aagtttgacc tcgtccagtg aacttttaat ggttacctct gttggagcag agctactggt
    33061 ctctgtctga ctagtgcttg agtttgtact acatgcacca agtaggagca agaagctggc
    33121 cactagggca gtgaaataaa gtttaaggga tgttttcata atttctcctt tttaaaatgt
    33181 gataacgatt tagggagtct cttgatctta ttgactaaga gactgaaggt tctctaactt
    33241 gagcttttat gttactagct atagatacag atctttttgt cattgatatc agctagcgtg
    33301 atgggaatct cataaagttg actgagcagg tcagcctgca tgatttgatc ggttcttccc
    33361 ttgctaaaga cctggccgtc cttgaaggcg acaatttcat ctgcatactg actggccatg
    33421 ttgatatcgt ggaggacgat gataatggtc ttgccgagtt cctccaccag tcgtcgaaga
    33481 atctgcatca tgctgacgct ttgcttgata tcgagattgt tgagtggttc gtccagcaag
    33541 ataaagtccg tatcctgggc cagtaccata gcgataaaga cgcgctggag ttgcccccct
    33601 gacaggctat tgatgtagcg gtcttttaag ttggtcagtt ccaaatagtt cagagtttct
    33661 cggatttttt cccagtcttc tgatctaagt cgacctcggc tgtagggaaa acgtccaaaa
    33721 ctgaccagtt cttcaacagt caatttggct tggtaattga ttttctgttt taggatggtt
    33781 agttcttggg ccagttcttg cgaattccag ctatcgattt cacgtccttt gatactgaga
    33841 actccctgat ctttcttggt tagtctgctc atgatggaga ggagagtcga ttttccagca
    33901 ccatttggac caataaaggc tgtcagtttt tgaggactga cttcaagcga aatgccttgc
    33961 aaaatatcct gtttttgaat ggatttgtca atgttttcca gtttcactga cgagacctcc
    34021 tatatagtaa gataaagaat aagaagccac ccacactctc aatgatcata ctgatacgaa
    34081 tttccagtgc aaagactcgt tcaatcaagg cttgccccaa ggttaagcta ataaatccaa
    34141 tcagaatggc cactataaag agtaacttgt gctgatagtc tttgacaatc aggtaggtga
    34201 ggttggccag cataaagccg aagaaggcca taggtcctac caaggcagtg gccgttgagg
    34261 tcaaaagcac gattccccag aggagctctt tctgttcttt ttcaacatcg agtcccaata
    34321 tctgagccgt ttctctttgc aggtgcaaga catctagaac gactgctttt cgaaagaaaa
    34381 agattgtcaa agcgaggatg atcagagaac cgatggctag gatggaagtg ttgagatgtt
    34441 gaaaggaggc aaaaagacta ttttgcagtt tatcgtattc gtttggatcc attaggactt
    34501 gaaggaaggt gctgatattt cgaaagagac ttctgagcgc tagacagatc agcaggatga
    34561 agaccaggtc ttgcttcatc agtgtcttca agtaaccttg taaggcgaga aagaagaggg
    34621 actggacaag aagtaagact aggaattcta agatagggga tttgccaagt tgaagaaact
    34681 tgctttcaaa aaccagtagt agggtttgta gtaggacgta gaaggattca attcccaaaa
    34741 tactaggcgt caggaagcga ttttccgtca gggtttgaaa actaatggtc gaaatcccag
    34801 tcgcgatggc taccaagaga taaacgatga tcttttggga acgcaacttc caagcaaagg
    34861 ctgacaagtg agtgatgggc caaaagtaga gaagacaagc tccgatggca agaataatga
    34921 gaatccagaa gagcttggta tgtttgcttt tagtctgcat cttttcgtcc ccctctccag
    34981 agaagtagga taaagacgag actaccgatg attcctagca agagactgac agacaactca
    35041 tagggcctaa tcagaactcg ggataggata tcgcaagcca gaactagatt ggcaccaacc
    35101 agtgcgacca tgagtttggt ttgacttaga ttatctccat agcacttgcg aacaagattg
    35161 ggaacgataa ctccgagaaa tggtaggcca cccacggtaa tcatggtgac gcttgtcgtt
    35221 agcgccacca gaaagagggc cagtttttca agtagggagt aggaaatccc caaactctcg
    35281 ctggtttctt tccctagatt catgatggtg aaggtttggg ataatttcca aacggttatc
    35341 aggatgatga ggcctaagaa gagccactca tactgatggg tctgaatcat ggagaaggag
    35401 ccctgggtcc aggcagtcat actctgaacc agattgaaac gataggcgat aacttctgtg
    35461 actgagccga taatcccgct atagatgatc ccaatcagag gcaacatcca cctttccttt
    35521 acagtaaaaa tggtcataaa ggctaggaag aagagggtga atacgatgga tgaaacaaaa
    35581 gcgaagagca tcttttgggt cagactagcc gatggaaaga caaaaaggct cagcaccatt
    35641 cccagtttgg cggcttcagt cgttccaact gtactcggtg cagcaaactg attttgggta
    35701 atagtctgca tgagaaggcc tgccatactc atactagagg cagtcaggag aatactgata
    35761 gttcttggga gacgggactc ttgaaagagg agccaggtct gctggtcgaa atcaaatagc
    35821 tttccccatg aaaaatcact ggtcccaatg ctaatagaga gaaagactag gagtagaagt
    35881 aagccaatta aataatgaga aagtttcata ccccgtcctt tcatgtagat ttggtatcga
    35941 aagatatctg cggatataaa tgtaacatta tttttctaat ctgtcaataa aatttctgac
    36001 aatttaataa atacaacaag gagagagcaa caagactttc tcctttgtta tcctattcta
    36061 aaatgttttt accttaatct gataaaataa tatcttcgag ggagtagcta gccgtccaat
    36121 caagatattg tttagctttt gaagcatctg ctaggacact ggctgggtca ctagcacgtc
    36181 gagcaacaat ctcgtgtggg attttttaat ttagtaattc ttcagcagtt ttaaagattt
    36241 ctttgatagt atagcctttt ttagttccta agttaaagat ttgagaagaa ctgtcttctt
    36301 gaaataggta gttcattcct ttaacatgag cctatgcaag gtccaagaca taaatgtaat
    36361 ctcgaataca tgaaccgtca tgtgtatcgt agtcatctcc aaatgttttt aagctatcat
    36421 tttgtcccaa tgcggtcttg ttgatatttg gaatgatgtg agttggattt ttcacacgca
    36481 gaccgtttga agcatccatt tcagccccag caacattaaa gtaacggaaa ataacatatt
    36541 tccagtcgta gcgattggcc atccagtaaa tcattcgttc gcccatcagt tttgtctctg
    36601 cataagggtt gatagggtcg agcagggtat cttcagtcac cggcttgtca atacagttat
    36661 ttccatagag agaagcagtc gaagagaaca tgattttttg aatgccaact tcagataaga
    36721 ctttgagaac ttggttcata ccagcaacgt tggcagtgaa gtatttactt ggattttcaa
    36781 tactttcgct cacaacaatt tcacctgcac aatggaggac agcatcaatc tgattttctt
    36841 ctaagtaaac cttcaaggcg ctagcatcat aaacatccag ttctttaaag ctagcacgac
    36901 tatccacagc cgctcgattt cctgtggaga gattatcgag gacatgcacc ttatagccag
    36961 catttaaaag agctttaacg gtatgggagc caatgtagct agtcccacct gtaacaagaa
    37021 ttgttttggt catgattttt tccttttcta gttttgtact atagtaaatt gaaataagat
    37081 atgaacaact ctattaggaa agtcaaatta atttctagaa atgttttagc agctacagcg
    37141 tactattcca aactcaacca actatatatt taaagaaaga agaaagggaa gccaactatt
    37201 ttctgtaaat ttcatgaaaa atccaaacaa ctttgatggt gtattgtttt ttgtttggaa
    37261 ataaatattc gagttaattt tggaatgttt actagatttt gcactacatg caagagaata
    37321 ctatcctttt ctaagataga gcaggactaa gatactaact tagaaatcca ccttcccact
    37381 atccttctcc tataaaaagt ggtaaaatgg atgaaagaaa gaaggaactg aaatgacaac
    37441 attattttca aaaattaaag aagtaacaga acttgctgca gtctcaggtc atgaagcgcc
    37501 tgtccgtgct tatcttcgtg aaaagttgac accgcatgtg gatgaagtgg tgacagatgg
    37561 cttgggtggt atttttggta tcaaacattc agaagctgtg gatgcaccgc gcgtcttggt
    37621 cgcttctcat atggacgaag ttggttttat ggtcagcgaa atcaagccag atggtacctt
    37681 ccgtgtcgta gaaatcggtg gctggaaccc catggtggtt agcagccaac gtttcaaact
    37741 cttgactcgt gatggtcatg aaattcctgt gatttcaggt tctgttcctc cgcatttgac
    37801 tcgtggaaag gggggaccaa ccatgccagc cattgccgat atcgtttttg atggtggttt
    37861 tgcggacaag gctgaggcag aaagttttgg catccgtcct ggtgatacca tcgtaccaga
    37921 tagttctgca attttgacag ccaatgaaaa aaatatcatc tcaaaagctt gggataaccg
    37981 ctacggtgtc ctcatggtaa gcgagctagc tgaagcttta tcaggtcaaa aactcggcaa
    38041 tgaactctat ctgggttcta acgtccaaga agaagttggt ctgcgtggcg ctcatacctc
    38101 tacaaccaag tttgacccag aagtcttcct cgcagttgat tgctcaccag caggtgatgt
    38161 ctacggtggt caaggcaaga ttggagatgg aaccttgatt cgtttctatg atccaggtca
    38221 cttgcttctt ccagggatga aggatttcct tttgacaacg gctgaagaag ctggtatcaa
    38281 gtaccaatac tactgtggta aaggcggaac agatgcaggt gcagctcatc tgaaaaatgg
    38341 tggtgtccca tcaacaacta tcggtgtctg cgctcgttat atccattctc accaaaccct
    38401 ctatgcaatg gatgacttcc tagaagcgca agctttctta caagccttgg tgaagaaatt
    38461 ggatcgttca acggttgatt tgattaaaca ttattaaacc ataagggagg tggtagggat
    38521 ggtagaacca aacctagaaa gccttataaa agatctttac aatcatgctc gacatgattt
    38581 gagtgaagat ttagttgctg ctctcctaga gactactaaa aaactgccta ctacaaatga
    38641 gcaattgcag gcagttcgtc tctcaggcct ggtcaatcgt gaattgctcc taaatcccaa
    38701 acatccagca cctgagttgc tcaacttggc tcgctttatc aaaagagaag aagccaagta
    38761 cagaggaact gcgacttctg cgcttatgta tgaggaactc tttaaaatgc tttgattcca
    38821 ttgtggatca aagcattttt tgtaagatct atctcgtgag cgttcaaata gtagtaacaa
    38881 ggaatcatga gaagtcagcc gagcccatag tagtgaagaa acttctgtaa tggaagtgga
    38941 gcgaagtgag gaatcgtcaa acggtagggg ataggctgtt tgaagggtgc tacgaaaaag
    39001 atagggtaag gtgaaattat agcgggatga aataagatat gaacaaattg attaggaaaa
    39061 tcaaatgaat ttatagaaat cttttagcag tcatggcgtc ctattctagt ttcaaaatgc
    39121 tataaatacg aacaaattga ttgggaaatt caaatcgctt tctatcaatg ttttagaaga
    39181 tacagtgctc tagtctaact tcaatatact ataaaagaac agatggaagc aattatgatt
    39241 tacttctatc tttaaaataa atggtctgat aggaaaaatg tgtcccctca taaaatatag
    39301 gatagtacga atggaaggct tttgtagact ggaggacgaa ggagtttaga aactctcgtt
    39361 aaaagttagt tgagccggag tatggtggtg tggataatta tcaaaaatta tttctaaatc
    39421 gaaatagttg acagttagaa cgatgagtgt tacaattatt ttattcattt cgatatcgaa
    39481 ataaattgga ggtgttatga aagatggtca tttgctagcc catcatattc gtttgttgaa
    39541 tgggcggatt tttcaaaagt tactgagtca agatcctgag gctctttata ggggtgaaca
    39601 gggcaagatt ttagcggttt tatggaatag tgaaactggc tgcgcaactg cgacagatat
    39661 cgcgcttgcg actggacttg cgaataatac gctgacgact atgataaaaa agctagagga
    39721 acaaaagctt gtaattgtta gtccgtgtgg aaaagacaag cgtaagaagt atttagtttt
    39781 aacggagtta ggcaagtccc agaaagaagt ggggcatcgt gtcagtcaga aattggatac
    39841 tatcttttac aaaggatttt cagaggaaga aattcaccaa tttgaaggtt ttcaagaaag
    39901 aattttggcg aatctgaaag agaagggaaa tgaggtttag aatatgtcac aacaagtgaa
    39961 aaatgctcac aacctataca tccatgccat tcaagacgga cgagttgctg aggctcaagc
    40021 ccagtctgta ggggatacct atatccaaca ttcgacaggt gttcctgacg ggaaagaagg
    40081 atttgcagcc ttctttgcag atttctttga gcgtcatcca gagcgtcaga ttaagattgt
    40141 ccgcaccatt gaggatggca atctggtctt tgttcatgtt catcaatatc tgaatggtgg
    40201 agaagctcaa tgggtgacga cggatacttt ccgtgcggat gagaatggtc gtattgttga
    40261 gcattgggat gtcattgact actatcgaac acctgaaaat gaccaactag atcaaatttt
    40321 tggagatttt gaaatcaagg atttggacaa gaaagcagaa aataaaaagc tggttcgccg
    40381 tttcttgaca gaaattttcc aaaatgggga gctagagcag tggagtgatt atgtggcaga
    40441 cgatttgatt cagcataatc atgatattgg acaaggaagt gctgcttata aaaactatgt
    40501 ggctgaatat agtgtcactt ttgactttgt tttccaactc ttaggacaag gaaactatgt
    40561 ggttagctat ggtcagactc agattgatgg cgttgcttat gcccagtacg atatcttccg
    40621 tttagagaac gggaaaattg tggagcattg ggataataag gaagtcatgc ctaaggtaga
    40681 agacttgacc aatcgaggga agttttaaat tgaggacaaa gaatgattga atacaaaaat
    40741 gtagcactgc gctacacaga aaaggatgtc ttgagagatg tcaacttaca gattgaggat
    40801 ggggaattta tggttttagt agggccttct gggtcaggta agacgaccat gctcaagatg
    40861 attaaccgtc ttttggaacc aactgatgga aatatttata tggatgggaa gcgcatcaaa
    40921 gactatgatg agcgtgaact tcgtctttct actggttatg ttttacaggc tattgctctt
    40981 tttccaaatc taacagttgc ggaaaatatt gctctcattc ctgaaatgaa ggggtggagc
    41041 aaggaagaaa ttacgaagaa aacagaagag cttttggcta aggttggttt accagtagcc
    41101 gagtatgggc atcgcttacc tagtgaatta tctggtggag aacagcaacg ggtcggtatt
    41161 gtccgagcta tgattggtca gcccaagatt ttcctcatgg atgaaccctt ttcggccttg
    41221 gatgctattt cgagaaaaca gttgcaggtt ctgacaaaag aattgcataa agagtttggg
    41281 atgacaacga tttttgtaac ccatgatacg gatgaagcct tgaagttggc ggaccgtatt
    41341 gctgtcttgc aggatggaga aattcgccag gtagcgaatc ccgagacaat tttaaaagcg
    41401 cctgcaacag actttgtagc agacttgttt ggaggtagtg ttcatgacta atttaattgc
    41461 aacttttcag gatcgtttta gtgattggtt gacagctcta tctcaacatt tgcagttgtc
    41521 acttttgacc ttgttactag ctattttgct tgcgattccc ttggctgttt ttcttcgcta
    41581 tcatgagaag ctggccgact gggtcttgca gattgcaggt attttccaga ccatcccgtc
    41641 tctggccttg ttgggactct ttattccctt gatgggaatt gggactttac cggcattgac
    41701 agctctagtg atttatgcga tttttccgat tttacaaaat actattactg ggctgaaggg
    41761 aattgatccg agtcttcaag aggctgggat tgcctttggg atgaccagat gggagcgtct
    41821 caagaagttt gaaattccac ttgccatgcc tgttatcatg tctggaattc ggacggcagc
    41881 ggtcttgatt atcggtacgg ctaccttggc gaccttgatt ggggcagggg gactgggttc
    41941 ctttatcctg ttgggaattg accgtaataa tgccagtttg attttgattg gggccctttc
    42001 ttctgcagtg ctagctattg cctttaactt cctactaaaa gtaatggaaa aagcgaaatt
    42061 gcggacgatt ttctctggtt ttgccttggt ggctttatta ctgggtctgt cttatagtcc
    42121 agcccttttg gctcaaaaag agaaggaaaa cttggttatt gctgggaaaa taggcccaga
    42181 accagaaatt ttggctaata tgtataaatt gctgattgaa gaaaatacca gcatgactgc
    42241 gactgttaaa ccgaattttg ggacgacaag tttcctttat gaagctctga aaaaaggtga
    42301 tattgacatt tatcctgaat ttaccggtac ggtgactgaa agtttgcttc aaccatcacc
    42361 caaggtgagt catgagccag agcaggttta tcaagtggcg cgtgatggta ttgccaagca
    42421 ggatcatcta gcctatctca aacctatgtc ttatcaaaat acctatgctg tagctgttcc
    42481 gaaaaagatt gctcaagaat atggcttgaa gaccatttcg gatttgaaaa aagtggaagg
    42541 gcagctgaag gcaggcttta cgcttgagtt taacgaccgt gaagatggaa ataagggctt
    42601 gcaatcaatg tatggtctca atctcaatgt ggcgactatg cagccagctc ttcgttatca
    42661 ggcaattcag tcaggggata ttcaaatcac ggatgcctat tcgactgatg cggaattgga
    42721 gcgttatgat ttacaggtct tggaagatga caagcaactc ttcccacctt atcaaggggc
    42781 tccactcatg aaagaagctc ttctcaagaa acacccagag ttggaaagag ttcttaatac
    42841 attggctggt aagattacag aaagccagat gagccagctc aactaccaag tcggtgttga
    42901 aggcaagtca gcaaagcaag tagccaagga gtttctccaa gaacaaggtt tgttgaagaa
    42961 atgatgggac agagacttta aacatactga actcaacttc cttaaacgac tagataaaag
    43021 aatgctcaga cagtttcgtc tgggcttttt tgatgtgaga atgactgaat gtcacttaaa
    43081 atggaaagaa agagaaaatt ttcatgattt tctaaaattt tactgtaaag acagttgact
    43141 attcataaaa taggtgtata atattttgtg aactacttaa caaataagag gtttcagctc
    43201 atgtcgacta aggttagaaa tcttgtgtat aggcagttca ttatctaata gagcgttgcg
    43261 tccgaaagtc tatccagaca cggctcttta aaaacaaaag gagaaatgat gcatacttat
    43321 ttgcaaaaga aaattgaaaa tatcaaagca accctaggtg aaatgtcagg tggttaccgt
    43381 cgtatggttg cggctatggc tgatttagga ttttcaggaa ctatgaaggc tatctgggat
    43441 gacctctttg cccatcgtag ttttgcccag tggatttatt tgctggtttt aggaagtttt
    43501 cctctctggc tggagttggt ttacgaacat cgtattgttg actggattgg gatgatttgt
    43561 agcttgacag ggattatctg tgtaatcttt gtatcggaag gtcgagcaag taattatctt
    43621 tttggcttga ttaactctgt tatttacctt attttggccc tacagaaagg cttttatggt
    43681 gaggtgctga cgacacttta cttcacagtc atgcagccaa ttggacttct agtttggatt
    43741 tatcaggcac agtttaagaa ggaaaagcag gagtttgtcg cgcgtaaact ggacggcaag
    43801 ggctggacaa agtatctttc cattagtgtg ctttggtggt tggcctttgg cttcatttat
    43861 cagtctattg gtgccaatcg tccctatcgt gattcaatca cagatgcaac caatggggta
    43921 gggcaaatcc tcatgacagc tgtttaccgt gaacagtgga tattctgggc ggctaccaat
    43981 gttttttcaa tctatctctg gtggggagaa agcctgcaaa ttcaagggaa atatctaatt
    44041 tatctcatta acagtctagt tggttggtat caatggagca aggcagctaa gcagaatact
    44101 gatttaccta actaggaaaa gatgtttgaa agtgctgttt tgagatttcg attaaaacag
    44161 atatagttga taatcaagga tttatagtat gaaaaagagg atcggcgggt cctcttttgt
    44221 tgttgaaaag ataaaaaact cagtaaccta gaaataagac aactgagctt tactctatat
    44281 tcaattttta ggaatgagaa ggtctagata aaattggaca acttcctggt ctgtgaaatc
    44341 ttgacctttt ttgagccacc aggtcaatgt ctcgataaag ttggacacga ccaagtgttg
    44401 gaggtaagaa gtaggcatat tagggtgggc ttcttttaaa ttatcagcta gcacggaata
    44461 gacatggtgt tctagctctt tatggagttg acggaggaag tagtcatttt tggaaaatag
    44521 cagactggtg atatggtctt ggtttttatg aaaatggaga aagaggtggg cgaggtagtc
    44581 ctcggttgaa atggcttgct ctctttcaaa aagatgatgg aagaggtagc ggcagagctg
    44641 gtccagaaga agctccttac tttcatagtg acagtaaaag gtggatcttc ccacatctgc
    44701 gagatcaatg atatcctgaa cagtagtggc ctcgtagccc ttagcattca aaagttgtat
    44761 aaaagcttga tagatggctt ttttggtttt gctgatacgg cggtcaatgt tagtcatatg
    44821 gacacttaag gcaaattgtt cagaactgaa taaagctgac gttttgcttc tatcctttct
    44881 ttgagtttta gtggataatg ataatgaaca aggtgttcat aaacctatta taacaaagga
    44941 atgagaaata tgaaggcaaa atatgctgtt tgggtggctt ttttcttaaa tttgacttat
    45001 gccattgttg agtttattgc aggtggagta tttggttcta gcgctgttct tgctgactct
    45061 gtgcatgact tgggagatgt gattgcaatt ggaatatcag cttttctaga aacaatctcc
    45121 aatcgtgaag aagacaatca gtacaccttg ggctataagc ggtttagcct gctaggagcc
    45181 ttggtaacag ctgtgattct cgtaacaggc tctgttctag tcattttgga aaatgtcacg
    45241 aagattttgc atccgcaacc agtcaatgat gaggggattc tctggttagg aattattgcg
    45301 attactatca atctgttagc gagtctggtg gttggtaagg gaaagacaaa gaatgagtct
    45361 attctgagtc tgcattttct ggaagatacg ctagggtggg tagctgttat cctgatggcg
    45421 attgttcttc gatttacgga ctggtatatc ctagatcctc ttttgtccct tgtcatttct
    45481 ttctttattc tttcaaaagc cctttcacgt ttttggtcta cactcaagat tttcttggat
    45541 gctgtgccag aaggtcttga tatcaagcaa gtaaagagtg gcctggaacg attggacaat
    45601 gtggccagcc ttaatcagct taatctctgg actatggatg ctttggaaaa aaatgccatt
    45661 gtccatgttt gtctaaaaga aatggaacat atggaaactt gtaaagagtc tattcgaatt
    45721 ttcctaaaag attgtggttt tcaaaatatt accattgaaa ttgatgctga cctagaaact
    45781 caccaaaccc ataagcgaaa ggtgtgtgac ttggaacgga gttatgagca tcaacattag
    45841 aaaaaagtga aaaatacttg ggtactatct tatttggaat agagtaattt ctttattatt
    45901 taaatatttc aaaaattggt aagagaagag cattgtataa actccagata tatgattgtt
    45961 aatgataaaa atttttcgat tagatacaaa atgcttgact tggagtcaac tcaaagttat
    46021 ataataagat aagtgagtta gaatagcgtg aattcagtga atgaaatgag aggaggttag
    46081 cgtgtgaata ttaaatctgc cagtgatttg ttgggaattt cagcggatac gattcggtat
    46141 tatgaacggg ttggtcttgt gccaccgatt actcgtactg ctactgggat tcgtgatttt
    46201 caagatcagg atatcgaagc gctggaattt attaagtgtt ttcgttcggc gggtgtctct
    46261 gtagatagtt tagttgacta tatgtcgctc taccaaaagg gagatgaaac gagagaggag
    46321 aggcttggta ttttagaaga ggaaaagcaa aaattagagg agcgcttgtc tcagctacag
    46381 acagctttaa atcgtttaaa tctcaaaatt aaactttata aggaaggaaa attttaaatg
    46441 aaatcagcag tatatacaaa ggcaggtcag gttggacttg ctagcattga acgtccgcaa
    46501 ataatagaag cggatgatgt gattattcgt gtggttcgtg cgtgcgtttg tggttcagat
    46561 ttatggaggt accgtaatcc agaaacgaaa gctggacaca aaaatagtgg acacgaagcg
    46621 attgggattg ttgaagaagc tggggaagcc attacgacgg tgaaaccagg tgattttgtg
    46681 attgtccctt ttacacatgg atgtggtgag tgtgatgcct gtcttgctgg atttgacggt
    46741 tcttgcgaca atcatattgg caataatttg gggggtgatt ttcaggcaga atatattcgc
    46801 ttccactatg caaactgggc gctggttaaa atccctggtc aaccttctga ctatacagaa
    46861 gggatgctca agtccctttt gactcttgca gatgtcatgc cgacaggcta tcatgcggcg
    46921 cgtgttgcaa atgttcaaaa aggggacaag gttgttgtta tcggtgatgg ggctgttggt
    46981 caatgtgctg tcatcgcggc taagatgcgt ggagcatcac aaattatcct tatgagccgt
    47041 catgaagacc gtcaaaagat ggctatggag tcaggtgcga cagctgttgt tgcagaacgt
    47101 ggtcaagaag gaattaccaa ggtgcgtgaa atcctcggtg gaggagcaga tgcagcactt
    47161 gaatgtgttg gtacggaggc tgctatagaa caggcgctag gtgttcttca taatggaggg
    47221 cgtatgggct ttgtaggagt cccacactat aataatcgtg ctcttggttc gacatttatg
    47281 caaaatatct ctgtagcagg tggggcagct tctgctacaa catacgataa gcaattttta
    47341 ctaaaagccg tccttgatgg tgatatcaat ccaggtcgcg tctttacttc aagttataaa
    47401 ctggaagata tcgaccaagc ctataaagat atggatgaac gtaagacaat taagtctatg
    47461 attgtaatcg aataaaaaac gaataggagt tttagaactc tattcgtttt ttatgttatc
    47521 ctattcttga tttagggtac tttctcttaa tgtcagtctg gttcccagca tggtcaggct
    47581 aggaattttg cgaccgtgga ggacttcctt gttaagaata tccatacctg ctcgccccat
    47641 ttcttcagta taaactgtga tgctggagag gggaggataa acctgcttgg tcaggctggt
    47701 gtcgttaaag gaaatgaggc tgacacggtc tggtaggctg attccagctt cttggagcgc
    47761 acgaagggca ccgatggcta aactatcgct ggctgcgaaa aatgctggtg ggagttggtc
    47821 tcccaagctc tgaatggctt ccttcatcaa gtcatagcca gactgggcag taaagtttcc
    47881 ttgaaagacc agttcatcat gatagattcc ttttgcttga ctgtagtttc tgaaattttc
    47941 cagccgctta tcctgaatga tttcttcttg gtcagtcgtt tcttcaaggc ctgttagaat
    48001 cccgatacgg tccattcctt ggctgaggaa ataatcgaca acctgtttca tagcagtgta
    48061 aaaatccgtg ataatacagg tatgtcccag ggaaagtgta tcactgtcta gaaagaccag
    48121 gggtttttgg tattcttcaa aggcagaaat ctgagctcgg ctaaattttc caatgcagag
    48181 aatcccaatc acttcctcgc ttaaggtaaa aggatggtca ttaaaatagc gcaagatatc
    48241 atagtccaac tcttgggctc ttttttctat tcctaggcga atctggtagt agtagaggtc
    48301 gtccagctcc ccttgttcgc tgacccattg tataatggca atcttttgct tgggtttatg
    48361 ggactcgcct gtcttgaggt gcttggtgta gcccagctct tcaacaacgg ttaaaatacg
    48421 gtgtctggtt tcttctgtaa cagataggct ctggtcgcgg ttgaggacac gggatacggt
    48481 cgcgatagag acagaggcta gctgtgcaat gtcttttaag gtagccataa atcctccttg
    48541 attaggttag tatatcatat ttttctgctt tttactgata ttttagtaaa attttagtaa
    48601 aaaggattga ccttgggaaa tcccttggat acaatagaag aaaacgatta cacgttaagg
    48661 tggcttaacg gacagtcaaa ggagaaatca tatgacacaa catcttactg ctgaaactct
    48721 tcgcaaagac tttcttgctg tttttggtca agaagcagac caaactttct tttcaccagg
    48781 tcgtatcaat ttgattggtg aacacacaga ctacaacggt gggcacgttt ttcctgctgc
    48841 tatttccttg ggaacttacg gtgcagctcg taagcgtgac gaccaagttt tgcgtttcta
    48901 ctcagctaac tttgaggaca agggcattat cgaagtgcct ctcgctgacc tcaagtttga
    48961 aaaagagcac aactggacca attatccaaa aggtgtcctt catttcttgc aagaagctgg
    49021 gcacgtgatt gacaaaggtt ttgattttta tgtttatggg aatataccaa atggtgctgg
    49081 tttgtcttct tcagcatcct tggagctctt gacaggagtc gtggcagagc atctctttga
    49141 tttaaaatta gagcgtctcg atttggttaa aatcggaaaa caaacagaaa acaactttat
    49201 cggagtcaac tctggtatca tggaccagtt tgctattggt atgggggctg atcaacgtgc
    49261 tatttacctt gataccaaca ccttagagta tgatttggtg ccacttgatt tgaaggacaa
    49321 tgtcgttgtt atcatgaaca ccaacaaacg ccgtgaattg gcggactcta aatacaatga
    49381 acgtcgtgct gagtgtgaaa aagcagtgga agaattgcaa gttgccttgg atattcagac
    49441 cctgggtgaa ttggacgagt gggccgttga ccaatatagc tatttgatta aagatgaaaa
    49501 tcgtttgaaa cgtgctcgcc atgctgtgct tgaaaaccaa cgtaccctta aagctcaagc
    49561 agcccttcaa gcaggtgatt tggaaacatt tggtcgtttg atgaatgcgt cacacgtttc
    49621 tctggagcat gattataaag taactggttt ggaattagat acccttgttc acacagcttg
    49681 ggcacaagaa ggagttctcg gtgctcgtat gacaggggct ggttttggtg gctgtgccat
    49741 tgccttggtt caaaaagata ctgttgaggc ctttaaggaa gctgtaggca aacactacga
    49801 ggaagtagtt ggatacgctc caagcttcta tatcgctgaa gttgcaggtg gcactcgcgt
    49861 ccttgactag tcaaaaggag gatctatagt gaccttagta gataaatttg taacacatgt
    49921 catttctgaa agttcatttg aggaaatgga tcgaatctac ctgaccaatc gtgttttggc
    49981 acgagtggga gaaggtgttt tggaagttga gaccaatctg gataaattga ttgacctcaa
    50041 ggaccagcta gttgaggaaa ccgttcgatt agagacgatt gaggatagtc agactgcgcg
    50101 tgaaatcctt ggtactgaac tgatggactt ggtgactcct tgtccgagtc aggtcaatag
    50161 tgacttctgg gaagcctatg cctactctcc tgagcaagcg atagaggatt tttatcaact
    50221 cagtcagaaa aatgactaca tcaaactcaa ggccattgct aaaaatatcg cttatcgtgt
    50281 tccatctgat tatggagaac ttgaaattac catcaatctc tctaagcctg aaaaggatcc
    50341 gaaagagatt gcggtagcca agttggtgca agctagtaat tatcctcagt gtcaactttg
    50401 tttagagaat gagggttacc atggtcgggt caaccaccca gctcgcagca accaccggat
    50461 tatccgtttt gaaatggttg gtcaggaatg gggtttccag tattcgccct atgcttactt
    50521 taatgagcat tgtatctttt tagatggcca gcatcgtccc atggccatta gtcgtcagag
    50581 ttttgaacgt ctgttggcta tcgtagagca gtttccagga tattttgctg gatctaatgc
    50641 cgacctgccg attgtggggg gctctattct aactcatgat cattatcagg gaggccgtca
    50701 cgtatttcct atggaattgg ctcccttgca aaagaccttc cgatttgctg gttttgagca
    50761 ggtcaaggct ggaattatca agtggccaat gtctgtccta cgcttgactt cggattccaa
    50821 agaggatttg attaacttag ctgataagat tttccaggaa tggcgtcagt attcagattc
    50881 tagtgtgcag attttagcag agacagacga gacaccgcat cacaccatca caccaatagc
    50941 gcgtaagcgt gatggacagt ttgagttgga cttggtcttg cgagacaatc agacttcagc
    51001 agagcatcct gatggcatct atcatcccca caaggatgtc caacatatca agaaggaaaa
    51061 tatcggcttg attgaggtca tgggcttggc aatcttgcca ccacgtctga aagaagaagt
    51121 ggagcaagtc gctagctatc ttgtaggaga agctgttaca gttgccgatt atcatcagga
    51181 gtgggcagac caactcaaat cccaacatcc agacctaacg gataaagaaa aagcccttgc
    51241 aatcgtcaag gactctgtgg gtgctatctt tgtgcgtgta cttgaggatg caggagtcta
    51301 caagcagaca gaacaaggtc agacagcctt tatgcgcttt gtggaacagg tcggaatttt
    51361 actagactag gagctttctc cttgcacagt cctataaaaa gtagtatcat agtgtcgttt
    51421 gaaatatcag gaggaaacga tgaaagactt tcattttgac gctatatctg cctttgaaaa
    51481 ttacgaaatt gaaaaaatga gagatggtca cgttgtggtg acgaccaaag tagtgaactc
    51541 gtcgctcaac tactatggca atgcccatgg tggctatcta ttcacgctat gtgaccaaat
    51601 cagtggtttg gtggttatct cgctgggact tgatggggtg acactccaat cctctatcaa
    51661 ctaccttaag gcaggaaaac tcgacgatgt attgaccatt aaaggagaat gtgtccatca
    51721 aggtcgtaca acctgtgtaa tggatgtgga tatcaccaat caagaaggca gaaatgtctg
    51781 caaagcaacc tttaccatgt ttgtcacagg ccagcggtca gaagacagac aggtaaggat
    51841 ataaagagta atttaataga gtgaggtgaa ttttggaatt tataagattt gccttactca
    51901 ttttttgata ttgatatgat ttaattctaa aatagaaaat ttagtaatgt ggtagaaaat
    51961 acaagagttg tgttttaatt tctatggtat aattaaaagc atgaagataa aagaaataaa
    52021 gaaagttact ttacaaccgt tcacgaaatg gacaggtggt aaaagacaat tattgcctgt
    52081 tattagagaa ttaataccta aaacctataa caggtatttc gaaccttttg ttggaggtgg
    52141 agctttattt tttgatttgg ctcctaaaga tgcagttatt aatgatttta acgctgaact
    52201 aataaattgc tatcaacaaa ttaaggacaa tcctcaagaa ttgattgaaa ttttgaaagt
    52261 tcatcaggaa tataattcaa aagaatatta tttagattta cgttctgcag atcgtgatga
    52321 aagaatagat atgatgtccg aagtacaaag agctgcacgt attctatata tgttgagagt
    52381 gaactttaat ggtctatatc gtgtgaattc taagaatcaa tttaatgttc catatggacg
    52441 ttataagaat cctaaaattg ttgatgagga attgatatct gctatttcag tttatataaa
    52501 taacaatcaa ctagaaatta aagtgggaga ttttgaaaag gcaattgtag atgttcgaac
    52561 aggagatttt gtgtattttg accctccata tattccattg tctgagacga gtgcatttac
    52621 gtcttatact catgagggat tctcttttgc agatcaagta agattaagag atgcctttaa
    52681 gagattgagt gatacaggag cttatgttat gttatcaaat tcttctagtg ctttagtaga
    52741 ggagttgtat aaggatttta atatacatta tgttgaagct acccgaacta atggagcaaa
    52801 atcttcaagt cgaggaaaaa tttctgaaat tatagtcaca aattatgaaa aataacgaat
    52861 ataagtatgg aggtgttctt atgacaaaac catactacaa taaaaataag atgattcttg
    52921 ttcattcaga tacgttcaag ttcttatcaa aaatgaaacc agaaagtatg gatatgattt
    52981 ttgctgatcc accttatttt ttaagtaatg gtggaatatc taattctggg ggacaagtag
    53041 tttctgttga taaaggagat tgggataaaa tttcttcatt cgaagaaaaa catgagttta
    53101 atcgtaaatg gattcgccta gcaaaagaag ttctgaagcc taatgggacg gtatggattt
    53161 caggtagttt gcacaacata tactcagttg gaatggcatt agaacaagaa ggttttaaaa
    53221 ttctgaataa tattacttgg cagaaaacaa accctgcccc caatttatct tgtcgttatt
    53281 ttacccattc tactgaaacc attttatggg ccagaaaaaa tgataaaaaa gctcgtcatt
    53341 actacaatta tgatttaatg aaagaattga atgatggaaa acaaatgaaa gatgtctgga
    53401 ccggttcttt aacaaagaaa gttgaaaaat gggctgggaa acatccaact caaaaaccag
    53461 agtatttgtt agaacgtatt attttagcct ctactaaaga gggtgactat attctagacc
    53521 catttgttgg tagtggcact acgggtgttg ttgcgaagcg gttaggtaga agatttatag
    53581 gtatcgatgc tgaaaaagaa tatttaaaaa ttgcaaggaa gaggttggag gcagaaaatg
    53641 aaacaaacta gaaattttga tgagtggttg tcaacgatga ccgacacagt agctgactgg
    53701 acttattata cagattttcc taaggtttat aaaaatgtat ctagtataaa agttgctcta
    53761 aatattatga atagtcttat tggtagtaaa aatatacaag aggatttttt agacttatat
    53821 caaaattatc cagaaatttt gaaagttgtg cctctactta ttgctaaacg tttgagagat
    53881 acgattattg ttaaggatcc gataaaagat ttctattttg attttagtaa acgaaactat
    53941 agtattgaag aatatactat gtttttggaa aaatcaggta tatttgattt attgcaaaat
    54001 catttagtat caaatttagt tgactacgtt acaggtgttg aggttggtat ggatactaat
    54061 gggcgcaaaa atcggactgg agatgcgatg gaaaatattg ttcaaagcta tcttgaagct
    54121 gaagggtata ttttaggaga gaatttattt aaagagattg aacaaaatga aatagaggaa
    54181 attttttctg tcgatttatc tgctattacg aatgatggga atactgtgaa acgttttgat
    54241 tttgtcataa aaaatgaaca agtgctttat ctgattgagg ttaattttta ttcaggaagt
    54301 ggttcaaaat taaatgagac ggctagatct tacaaaatga ttgctgaaga aactaaagct
    54361 attcctaatg ttgagtttat gtggattact gatggacaag gttggtataa ggctaagaat
    54421 aatttacgag aaacatttga tattttacca ttcttatata atattaacga tttggaacat
    54481 aatattttaa agaatttgaa ataggtccaa ttcaattaga tgggaattgg gattgattgt
    54541 atttataatc aatttgtgat aaacaaaaaa gaggctcgca cctctttttc ttatttcttt
    54601 ttatgattta atacggcatt gaggacaatg gcgagtaggc tggctacgac gattccgttt
    54661 gagaagaaca tttggaaggc tgtcggcatg ctgacaaaga gattactgtt gttgagaccg
    54721 acacctgcag cgattgaaac agctgcgata aggaagttgt gttcattgtt agcaaagtca
    54781 actcgggcga ggatttgcat cccttgaata gatacaaaac caaacatcac cagcatggca
    54841 ccgccgagga cggagcttgg aatgatttgg gcaagggcac caaacttagg aagcagtcca
    54901 aggagaacca ggaaaccagc tgcgtagtag attggcaggc gttttttgat gcctgacaat
    54961 ttaaccaaac caacgttttg tgaaaatccg gtgtaaggga aggtgttaaa gattcctccg
    55021 agaagtacgg ccaaaccttc tgcgcggtaa ccgttgcgaa ggcgcgtgct gtcgattgga
    55081 tcttttgtga tatcagacaa ggctagataa acaccagttg actcaaccat agacaccgtt
    55141 gcgataatac acatcatgac aatagatgag atttcaaagg ttggcatccc aaagtagagt
    55201 ggagttggga catggacaag tggagctacc gcaacaggag agaagtccac caagcccata
    55261 gtagcagcaa tggcagttcc aacaaccaga ccaatcaaaa tagagataga cttgataaat
    55321 cctttggtaa agatgttgat caagaggata atcagaacag taatagctgc aagcaagaga
    55381 ctttgaccag ttggctctgg aacgttattt cccatatttc caatagcgac agggatcaag
    55441 gttaaaccaa tcgtggtaat aacagatcct gttacgatag atgggaagag attggctact
    55501 tttgagaaga tgcctgaaac aagaaccacg taaatcccag atgcgataag ggcaccaaac
    55561 atagcgccac taccatggct ttgcccaatc ataatcaagg gagcgaccga ctggaatgca
    55621 actccaagaa cgactgggag tccaatccca aagtatttgt tgagttggag ttggaggaag
    55681 gttgccaccc cacacatgaa gatatctgta gaaatcaggt aggtcaactg ctcagctgaa
    55741 tagccaaggg ctgtcgcaat catgatggga accaggatag atcctgagta catggctagt
    55801 aagtgctgca agccaagaac ggctgcttgc gagtgttttt cttgagtttg cattagagat
    55861 ctgcctcctt aaatacgacc tgaccatttt caaaacgatc caaacgagca agtgatagga
    55921 cagggtagcc tgctttttca agcaaatcac ggccatcttg gaaggatttc tcaatcacga
    55981 taccgatagc ttggactgtg gcaccggcct gttcgatgat ttgaatcaag cctttagcag
    56041 cttggccatt agcaaggaaa tcgtcgataa tcaaaacctt gtcctctggt gagaggaatt
    56101 ttccagcgat agaaacggtg ctggtcacct gtttggtaaa ggagtagact tgagcagtta
    56161 agatgccttc gttcatggtg atgttcttag cttttttggc gaaaatcatg ggaacgttta
    56221 aggcttcagc tgtaaaaacg gctggggcaa tacccgacgc ttcaatggtt acgaccttgg
    56281 taatgccagt agcagcaaat ttttccgcaa aaaccctacc aatctctcgc atcaagctaa
    56341 agtcaacttg gtgggttaaa aaggaatcta ccttgaggat gttatcaccc aagatatgcc
    56401 catccttgag gatgcgctct tctaataatt tcataagacc tcctaaagtc taaaagttaa
    56461 tttacttgtt gtttaaatat ttctatagtg atcccttttg ctaatactat atatttgata
    56521 aaactattac gagcgaagcg agtcttatca aatatttccc gttgtagtgg tatcatagac
    56581 aataatcttg ttattgtcta tgacgggatt tttgagagta aaatagttcg gggaactatt
    56641 ttagcctaag cctagaaatg aaagagctag gggctcaaaa attagggatg aaattccctg
    56701 gattcctgaa attattcaca ggataatttc acctcccgtc cgcactaatt aagggaaata
    56761 ttaaaaatat tcaaaaaaga cctacttaat ctctaagtaa gtcccctaaa tagacatggc
    56821 aaaaacggcc atatctcact gctgacttac ttattgttag gtgttccggc accttgtaga
    56881 aacgtcgtgc caattcacga cataaacaag taaaacgata ttcaatttta aataggcttg
    56941 agccaatgtt tttattttac actaaataac tttataaatc aactattttg ttagtgtttt
    57001 ggtttaaaaa acgaacaaac agaagagggg gtgaacaaaa actccattgt aagctaacat
    57061 ttatactaaa tgaaaatcaa agagcaaact aggaagctat ccacaacctc aaaacactgt
    57121 tttgaggttg tggatagaat tgacagagtc agtatcatat acctacggta aggcgacgtt
    57181 gacgtggctt gaagagattt tcgaagagta ttagaagatt tttctatcat aaaaggcata
    57241 ctatcaagtt tttagacacc tgacaatatg cctttttcta actttaaaga cttttcccaa
    57301 tttttattat tctactcgct aaatcttaaa aaatagccat ctggatccaa aactgcaaat
    57361 ttatgaggat agatataggg atcactgaca cgaaactttc ttttggtcaa gggacgataa
    57421 ataggatagt ttgcctccat cactttttga tagagttttg gaacatcctt tatgccaaag
    57481 gagagattga ctccacgacc aaaggggtag gtcagttcag ctagttgatc ctttgttccc
    57541 tcctctaaca ttagttgaca ctcttcaaga gaaagagaaa gttttcttct ggacgttggt
    57601 attcaatcct aaaacccagt aaaccacagt agaaggaccg ggactgttcg atattcgata
    57661 caagaaactc gggaatgacc gcattgtagt ccatatagaa aatccttaca agtcaatttc
    57721 caagacaatc ggtgtatggt cttggcgagc acctgagtca atcatatcag atttagtgac
    57781 cttgtcagcg atacggttac ttgtgagcca gtagtcgatt ctccagcctg tattgttgat
    57841 tttagaagtt ttgctgcgtt gtgcccacca agtgtagcgt tcaggaacat cgccatgaac
    57901 atggcggaag gtgtctgtaa atccagttgc caaaaggttg gtaaatccag cacgttcctc
    57961 gtcagtaaat ccaggtgaac ggcggttgct agcaggattt gcaaggtcga tttcattgtg
    58021 ggctacgttg tagtcaccgg tcgcaaggac tggtttttct ttgtctagtt cagccaaata
    58081 ctcagcatat ttaacatccc agacttggcg ttcttccaag cgtttgagac cgtcaccagc
    58141 gtttggagtg taaacttggg ttacgaaaaa tgcatcaaat tctagagtga tgatacggcc
    58201 ttccaagtcc atggtagaag gggcaccgat ttctgggaag ctgatcgtag gtgtaagttc
    58261 tttcttataa aggaacatgg ttccagcata gcctttacgg gcaggctctt gggaagaacg
    58321 ccacgtgttt tcgtagcctg ggaagagttc ttctaaaatt tccacgtgtt tctttgtagg
    58381 tcctttggca gaaagcttgg tttcttggat agcaatgata tcagcatttt cagcgaccaa
    58441 ggtttgtagg acttcttggg acaatttggc acgagctgag tcactagtta gggcagcgtt
    58501 tagggaatca atattccatg agataagttt cataaagtta cctttttcat tcagattata
    58561 gattttatta taccaaaaaa agatctattt ccccaacgta tagtttgaaa aattactctc
    58621 tttcgtttat aattaagaat gattttatga aagggagtga aaatacatga aattctactc
    58681 ttatgactat gtactcagcc aaatcggtca gcaaaatggt atcatggttg gctttgggat
    58741 tgttctatta gctgtgacag ttttttttgc ttttaaggca taccatgata aaaagggaac
    58801 cgaatttcgt gagttggtca tgatttcagc tctggcctta tttagctctg cttttggtca
    58861 gcatcacgac ttatcaaaac aatcaagttt ctaacaataa atttcaaact tcacttcatt
    58921 tcatcgaggt tgtttccaaa gatttgggag tagacaagtc agaagtctat gttaatactt
    58981 ccacaaacac agatggcgca cttatcaagg tgggagatcg ctattatcgt gccctaaacg
    59041 gaagtgagcc agacaagtac ctgttagaga aagtcgaatt gtataagaca gacgcaattg
    59101 aactggtgga tgtgaacaaa tgacacttaa ttatatcgaa attttaatca aactggtctt
    59161 gactctcaaa tagctcaaca acaatgttca ctttgtgaaa tgtttgattg atggtaagcc
    59221 aactctcctt atcaaaaatg ggaatattga cccagaagcc tgtcgttcag ttggtttgtc
    59281 tgcatcggat gtagccctca aacttcgtag ccaagggatt ttccagatga agcaagtcaa
    59341 acgagctgtg caagagcaaa atgggcaact catcgttgtg caaatgggag atgaaaatcc
    59401 taagtatcca gttgtgactg acggtgtgat tcaagtagat gtcttggaat cgattggtcg
    59461 tagcgaagag tggttgcttg ataacctcag taaacaaggg catgacaatg tagccaatat
    59521 ctttattgct gaatatgaca agggtgctgt tacagtcgta acttataaat aagaaaaacc
    59581 tggggtcttg tactcttcga aaatctcttc aaaccgcgtc aacgtcgcct tgccgtatgt
    59641 aggttactga cttcgtcagt tctatctaca acctcaaagc agtgctttga gcagcctgcg
    59701 gctagtttcc tagtttgctc tttgattttc attgagtatt ggcctcaggt ttccatttgc
    59761 aatcagaaag ggattttatg tccattattc aaaaactctg gtggtttttc aagttagaaa
    59821 aacgccgtta tctagtcggg attgtggccc tggtcttggt ttccgtcctc aatctcattc
    59881 ctcctatggt tatggggcga gtcattgatg ccatcacatc ggggcaatta acccagcagg
    59941 acctccttct tagcctattt tacttgctac ttgcagcctt tggtatgtac tatttgcgct
    60001 atgtgtggcg tatgtatatc cttgggacct cttattgctt gggacagatc atgcggtctc
    60061 gcttgtttaa gcatttcaca aaaatgtcgt cagcctttta tcaaacctat cggacgggtg
    60121 atctgatggc acacgcaacc aatgatatca atgccttgac tcgtttagca ggtggcggtg
    60181 tcatgtctgc ggtggatgcc tctatcacgg ctctggtgac tttgttgacc atgctcttta
    60241 gcatctcatg gcagatgact cttgttgcca ttctccccct acctttcatg gcctatgcga
    60301 ctagtcgcct agggagaaag actcataagg cctttggcga atcccaagct gctttttctg
    60361 aactcaataa caaggtacag gagtccgtat caggtatcaa agtgaccaag tctttcggtt
    60421 atcaggcaga cgagttgaag tcttttcagg cagtcaatga attaaccttc caaaagaacc
    60481 tgcaaaccat gaaatatgat agtctctttg accctatggt tctcttgttt gttggttcgt
    60541 cctatgtttt aacgcttttg gttggctcct tgatggttca ggaagggcag attacagttg
    60601 gtaatctagt cacctttatc agctatttgg atatgctggt ctggcctctt atggccatcg
    60661 gcttcctctt taatactact cagcgaggga aggtttctta ccagcggatt gaaaatcttt
    60721 tgtctcagga atctcctgta caagaccctg agtttcctct ggatggtatt gaaaatgggc
    60781 gtttggagta taccattgac agctttgctt ttgaaaatga ggaaacactg acggatattc
    60841 actttagttt ggcaaaaggg caaacactgg gcttggttgg gcagacaggc tctgggaaaa
    60901 cgtccttaat caagctcctc ttgcgtgaat acgatgtgga taagggtgcc atttatctaa
    60961 acggtcacga tattcgggac tatcgtctga cagaccttcg cagtctcatg ggctatgttc
    61021 ctcaggacca gtttctcttt gcaacttcaa tcctagacaa tatccgcttt ggcaatccta
    61081 acttgcccct ttcagcggcc gtggaagcta ctaagctagc ccgagtttac caagatattg
    61141 tagacatgcc tcaaggattt gatacgctga ttggtgaaaa aggagtcagt ctttctggtg
    61201 gtcaaaagca acggttggct atgagtcggg ctatgatttt agaccctgat atcttgattt
    61261 tagatgattc cttatccgcc gtagatgcca agacagagta tgcgattatc gacaacctca
    61321 aggagacgcg aaaggacaag acaaccatta tcactgccca tcgcctcagt gctgttgtcc
    61381 atgcagattt tattttagtt ctacaaaatg gtcaaattat cgaaagaggc aggcacgaag
    61441 acttgctagc gatggctggc tggtatgccc aaacctacca gtctcagcag ttggaaatga
    61501 aaggagaaga agatgcagaa taaacaagaa caatgggctg tattgaagcg cttgatgtct
    61561 tatctcaagc cttatggact cctgaccttt ttggcactca gttttctcct agcgacgacg
    61621 gtcattaaaa gtgtcatacc cctcgtggct tcccacttta tcgaccagta tctcagcaat
    61681 cttaaccaac tagccgttac cgttttgctg gtctactatg gtctctacat cctacaaact
    61741 gtagttcagt atgtcggcaa tcttctcttt gcgcgcgtgt cttacagtat tgttagggat
    61801 attcgtcggg atgcctttgc caatatggag aaactgggca tgtcttactt tgacaagacg
    61861 ccagcaggtt ctatcgtttc tcgtttgacc aacgataccg agacgattag tgatatgttt
    61921 tctgggattt tatccagctt tatctcagca gtttttatct ttctgacaac cctttatacc
    61981 atgttggtgc tggattttcg tttgacggct ttagtcttgc tctttctccc tttgattttc
    62041 cttttggtca atctctatcg aaaaaagtca gtgaaaatca tcgagaaaac cagaagtctc
    62101 ttgtcagata tcaatagtaa gctggcagag aatatcgagg gaatcagaat aatccaggcc
    62161 tttaatcaag agaagcgcct gcaggcagaa tttgatgaaa tcaaccaaga gcacttggtc
    62221 tatgccaacc gttctgtagc cttggatgcc ctctttttga gacctgccat gagtttgttg
    62281 aaacttctag gttatgctgt cttgatggcc tattttggct atcgtggtct ttctatcggg
    62341 ataacggtcg ggaccatgta tgcctttatc cagtacatca accgcctttt tgaccccttg
    62401 attgaggtga cgcaaaactt ttcaactctg caaacgtcta tggtttctgc aggccgtgtc
    62461 tttgccttaa tcgatgagag gacctatgaa cctcttcaag aaaatgggca ggctaaagtc
    62521 aaagaaggca atatccgttt tgaacatgtg tgtttctcgt atgacggtaa acatccgatt
    62581 ctggatgaca tttctttctc tgttaataag ggtgaaacca ttgcctttgt aggtcataca
    62641 ggttcaggga aatcgtctat tatcaatgtc ctcatgcgct tttatgaatt ccagtcaggg
    62701 agagttctct tggatgatgt ggatatcagg gatttcagtc aagaagagct gagaaaaaac
    62761 atcggtttgg ttttacagga acccttcctc tatcatggaa ctattaagtc caatatcgcc
    62821 atgtaccaag aaatcagtga tgagcaggtt caggctgcgg cagcctttgt ggatgcagat
    62881 tcctttattc aagaacttcc tcaggggtac gactcccctg tttccgagcg tggttcgagc
    62941 ttctctactg ggcagcgcca gcttcttgcc tttgctagaa cagtcgccag ccagcctaaa
    63001 atcctgattt tggatgaagc gacagccaat attgactctg aaacagaaag cttggttcaa
    63061 gcttctctgg cgaagatgag acagggccga acaactattg ctatcgctca ccgcctttct
    63121 actattcaag acgccaactg catctatgtc ttggataagg gacgcattat cgagagtgga
    63181 acccatgagg aactcttggc tctgggagga acctatcaca agatgtatag tttgcaggca
    63241 ggggccatgg cctatactct ttgaaaatct ctttaaacca tgtcagcttt atctgcaatc
    63301 tcaaagctgt actttgattt tcattgagta ctagaaggaa atccttcaaa ttacagattt
    63361 ctttcaccgc cttttccatt ttgtggtata atgaaaaatg ttgacaaata gtataataaa
    63421 aacaaaggag aacagcatgc tgaaatggga agacttgcct gtggaaatga aatcaagcga
    63481 ggttgagtct tactaccagc ttgtctctaa aaggaagggt tcgctgattt tcaagcgttg
    63541 cttggactgg tttttggcct tggtcttact ggttctaacc tctcccatct ttctcatctt
    63601 gagcatttgg atcaagttgg atagtaaggg gccagtgatt tacaagcaag agcgtgtgac
    63661 ccagtacaac cgtcggttca agatttggaa gttccgtacc atggtgacgg atgcggataa
    63721 aaaaggaagt ctggtgactt ctgctaacga tagccgtatt accaaggttg gaaatttcat
    63781 ccgacgtgtc cgtttggacg aactgcctca gttggtcaat gtccttaaag gtgagatgtc
    63841 ctttgtcggt acacgacctg aagtgccacg ttatacagag cagtatagcc ctgaaatgat
    63901 ggcaaccttg ctcttgcaag cagggattac ctctccagcc agcatcaact acaaggatga
    63961 ggacaccatc atcagtcaaa tgacgaagaa aggtctgtca gttgatcagg cctatgtgga
    64021 gcatgttctt cctgaaaaga tgcactataa cctcgcctat ctccgagagt ttagtttcct
    64081 tggggacatc aaaatcatgt ttcaaaccgt atttgaggta ctaaaataaa gtagtcataa
    64141 gaaaatgagt acagataaaa ggagcaaatc aatgccaaat tacaatattc cattttcacc
    64201 gcctgatatc acagaagcag aaattgctga agtagcggat accctgcgtt ctggttggat
    64261 cacaacaggt cctaaaacaa aagaactgga gcgccgcttg tctctttaca cacagacacc
    64321 taagactgtt tgtctcaact ctgcgacagc cgctctggag ttgattttac gcgttttgga
    64381 agtgggacct ggtgatgaag tcatcgttcc agccatgacc tatacggctt catgtagtgt
    64441 cattacgcac gtgggagcaa cccctgtcat ggtggatatc caagcagata cgtttgagat
    64501 ggactatgac ctgcttgagc aagctatcac tgagaaaact aaggtgatta tcccagtaga
    64561 gctcgcaggg attgtttgcg attatgaccg tttgttccaa gtcgtggaga aaaaacgtga
    64621 cttctttact gcttcaagca agtggcaaaa ggcctttaac cgtattgtca ttgtctctga
    64681 tagtgcccac gctttgggat ctacttataa aggacaacct tctggttcta tcgctgactt
    64741 tacttccttc tcattccatg ccgttaagaa ctttacaacg gcagaaggtg gaagtgcgac
    64801 ttggagagcc aatccagtga ttgatgacga agagatgtac aaggaattcc aaatcctttc
    64861 ccttcacggg caaactaagg atgctcttgc caagatgcaa ctggggtcat gggaatacga
    64921 tatcgttaca ccagcctata agtgcaacat gaccgatatc atggcttcac ttggtttggt
    64981 acaattggac cgctatccaa gtttgttgca acgccgtaag gacattgtgg accgctatga
    65041 tagtggtttt gcaggttctc gcatccatcc tttggcacac aagactgaaa ctgtcgaatc
    65101 ttcacgccac ctctacatca cccgtgtaga aggagcaagc ctagaagaac gcaacctcat
    65161 catccaagaa ttggctaaag caggaattgc aagtaatgtt cactacaaac cgcttcctct
    65221 cttgacagcc tataagaatc ttggatttga tatgacgaac tatcctaaag cctatgcctt
    65281 ctttgagaat gaaattaccc tccctcttca tactaaatta agcgatgaag aagtagacta
    65341 tatcattgag actttcaaaa cagtttctga aaaagtgcta actttatcaa aaaaatgaca
    65401 aactacagtc aagcgaaagt gatcctgtcc ctaaaaagtc taattgagtg taaaaactgt
    65461 tgttttcaat tgataatagt ttacacctgt agttgaggcc tctttctcct cagagagaga
    65521 atttttatag gattttcctt tcttgtggga gtcccgtggt ttgaaataag atgtgagcaa
    65581 tttggtgtag catttagaat ccttactaga catcatttag aaaatctagt gtcttgttct
    65641 agttttcaat tcaccctatt ttttgaaaga cgtgagtttc catgagtgag attgtggaaa
    65701 ctcgcgtctt ttttttgttt tcagaatatt gttcaaagtt ttgtgcctgt ctttcatgtt
    65761 ctagtcattc ttttgcatga tagaatttat aacatgttga tattataata atgcaaatat
    65821 tctatatgtt tagtgatgct tgctatacat cattagatct cctgcgagac aatctataaa
    65881 acacttgtct actattacct atatgcccta ttccagtatt ttagaagcac tgcatctatt
    65941 tttatcgagg ttaaatctag cttttataga aggtctattt aagaaatata ttgtagtgtt
    66001 ttagtttcaa tccgccatat gagcgatatt catgtaaata tccctggcga atgcttgtat
    66061 gacaaggtat ttgttctttc atttataatt tacaacatat caataaattt aaatatagta
    66121 aatgggatat tttatattca agctaagaaa gatagcatca cttttgaatg gaaggctaaa
    66181 gagcaaacta ggaagttggc catagatagc tcaaaaccct gctttgaggt tgtagatata
    66241 gtaaaaggaa ataagaatag gacaaatcga tcgggacagt caaatcgatt tctaacaatg
    66301 ttttagaagt agaggtgtac tattatagtt tcagtctact atagaactga ccaagtcagt
    66361 aacctagact tagggcaagg cggcactgac ctagtttgaa gagatttccg aagagtataa
    66421 attttaatat tttcttgtgt tattccttga caattcaatt tggaaaatat atgataaaga
    66481 taatgacagc ggtgtcattc tatctatttt aagaaaagta ataatcaatt gttaaaaata
    66541 gtaaaaaaat tggaggttct gatgaaatat tttgttccta atgaggtatt cagtattcgt
    66601 aaattaaagg tggggacttg ctcggtacta ttggcaattt caattttggg aagccaaggt
    66661 attttatcgg atgaagttgt tactagttct tcaccgatgg ctacaaaaga gtcttctaat
    66721 gcaattacta atgatttaga taattcacca actgttaatc agaatcgttc tgctgaaatg
    66781 attgcctcta attcaaccac taatggttta gataattcgt taagtgttaa tagtatcagc
    66841 tctaatggta ctattcgttc caattcacaa ttagacaaca gaacagttga atctacagta
    66901 acatctacta atgaaaataa gagttataag gaagatgtta taagtgacag aattatcaaa
    66961 aaagaatttg aagatactgc tttaagtgta aaagattatg gtgcggtagg tgatgggatt
    67021 catgatgatc gacaagcaat tcaagatgca atagatgctg cagctcaagg gctaggtgga
    67081 ggaaatgtat attttcctga aggaacttat ttagtaaaag aaattgtttt tttaaaaagt
    67141 catacacact tagaattgaa tgagaaagct acaattctaa atggtataaa tattaagaat
    67201 cacccttcca ttgtttttat gacaggttta tttacggatg atggtgcgca agtagaatgg
    67261 ggcccaacag aagatattag ttattctggt ggtacgattg atatgaacgg tgctttgaat
    67321 gaagaaggaa ctaaagcaaa aaatctacca cttataaatt cttcaggtgc atttgctatt
    67381 gggaattcaa ataacgtaac tataaaaaat gtaacattca aggatagtta tcaagggcat
    67441 gctattcaaa ttgcaggttc gaaaaatgta ttagttgata attctcgttt tcttgggcaa
    67501 gccttaccca aaacgatgaa ggatgggcaa atcataagta aggagagcat tcagattgaa
    67561 ccattaacta gaaaaggttt tccttatgcc ttgaatgatg atgggaaaaa atctgaaaat
    67621 gtgactattc aaaattccta ttttggcaaa agtgataaat ctggggaatt agtaacagca
    67681 attggcacac actatcaaac attgtcgaca cagaacccct ctaatattaa aattttaaat
    67741 aatcattttg ataacatgat gtatgcaggt gtacgtttta caggattcac tgatgtatta
    67801 atcaaaggaa atcgctttga taagaaagtt aaaggagaga gtgtacatta tcgagaaagc
    67861 ggagcagctt tagtaaatgc ttatagctat aaaaacacta aagacctatt agatttaaat
    67921 aaacaggtgg ttatcgccga aaatatattt aatattgccg atcctaaaac aaaagcgata
    67981 cgagttgcaa aagatagtgc agaatattta ggaaaagtat cagatattac tgtaacaaaa
    68041 aatgtaatga ataataattc taaggaaaca gaacaaccaa atattgaatt attacgagtt
    68101 agtgataatt tagtagtctc agagaatagt atattcggtg gtaaagaagg aattgttatt
    68161 gaggattcaa agggtaaaat aaccgtttta aataaccaat tttataattt atccggtaag
    68221 tatatatcat tcatcaaatc taatgcaaat gggaaagaac ctgttatacg tgatagcgat
    68281 ggtaatttca atattgtaac ggagaatggg ctttacaaaa ttgtaacaaa taatttaagt
    68341 gataaaaacg aaaaagaaaa aaacaaagag gaaaaacaat ctaattcaaa taatgtaatt
    68401 gatagtaacc agaagaacgg agagtttaac tcaagtaaag ataatagaca aatgaatgac
    68461 aagatcgaca ataaacaaga taataagaca gaagaagtaa actataaaat agttggagat
    68521 ggcagagaaa ctgaaaatca tattaataaa tctaaagaaa tagtagatgt aaaacaaaaa
    68581 ttaccaaaga ctggttcgaa caagattatg gaactattct taacagtgac aggaattggt
    68641 ttacttttga cactaaaagg gttgaagtat tatggtaaag ataaataaaa tttgttcgat
    68701 acaaggaagt tccgtagaaa atgaggatat tgtaggttca caaaatcagt atttttggat
    68761 tattggtgga gctacagatt tatataattc taaagaggag ataggttatt cagtctcaga
    68821 agttgtacat attttatcag aaagtttgtc ggttaattgt aaagaatcaa aaactcttaa
    68881 acaaatattt gaaactgctt tactcgaggt taaagatgaa atcggtttaa actcatatga
    68941 attaacagag tatagtaaaa tgaaataata ataggacaaa tcaatcagga cagtcaaatc
    69001 gatttctaac aatgttttag aagtagacgt gtactattct agtttcaata tactatatta
    69061 tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt tggagtatat
    69121 gatgctaggt gactgcgtca tgttagtaaa cgaaatggaa ataactgatc atagagtaga
    69181 taacttattt gaa
//
LOCUS       DAVKZI010000006        63127 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKZI010000006 DAVKZI010000000
VERSION     DAVKZI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.006"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VXB18_000463"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VXB18_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0381720.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VXB18_000464"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VXB18_000464"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0381721.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VXB18_000465"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VXB18_000465"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0381722.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VXB18_000466"
     CDS             complement(3795..5063)
                     /locus_tag="VXB18_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0381723.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VXB18_000467"
     CDS             complement(5183..5551)
                     /locus_tag="VXB18_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0381724.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VXB18_000468"
     CDS             complement(5544..5810)
                     /locus_tag="VXB18_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0381725.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VXB18_000469"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VXB18_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0381726.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VXB18_000470"
     CDS             complement(9378..9947)
                     /locus_tag="VXB18_000470"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0381727.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VXB18_000471"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VXB18_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0381728.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRVAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VXB18_000472"
     CDS             complement(11217..11411)
                     /locus_tag="VXB18_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0381729.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VXB18_000473"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VXB18_000473"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0381730.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VXB18_000474"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VXB18_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0381731.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VXB18_000475"
     CDS             complement(14345..15103)
                     /locus_tag="VXB18_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0381732.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VXB18_000476"
     CDS             complement(15161..16342)
                     /locus_tag="VXB18_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0381733.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VXB18_000477"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VXB18_000477"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0381734.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VXB18_000478"
     tRNA            17048..17121
                     /locus_tag="VXB18_000478"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VXB18_000479"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VXB18_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0381735.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VXB18_000480"
     CDS             17432..18757
                     /locus_tag="VXB18_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0381736.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VXB18_000481"
     CDS             18754..19506
                     /locus_tag="VXB18_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0381737.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VXB18_000482"
     tRNA            19558..19629
                     /locus_tag="VXB18_000482"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VXB18_000483"
     tRNA            19635..19708
                     /locus_tag="VXB18_000483"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VXB18_000484"
     CDS             complement(19749..20291)
                     /locus_tag="VXB18_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0381738.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..22032
                     /locus_tag="VXB18_000485"
                     /pseudo
     CDS             20470..22032
                     /locus_tag="VXB18_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(22062..24614)
                     /locus_tag="VXB18_000486"
     CDS             complement(22062..24614)
                     /locus_tag="VXB18_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0381739.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTKAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24676..26298)
                     /locus_tag="VXB18_000487"
     CDS             complement(24676..26298)
                     /locus_tag="VXB18_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0381740.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26504..27529
                     /gene="trpS"
                     /locus_tag="VXB18_000488"
     CDS             26504..27529
                     /gene="trpS"
                     /locus_tag="VXB18_000488"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0381741.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27681..29159
                     /gene="guaB"
                     /locus_tag="VXB18_000489"
     CDS             27681..29159
                     /gene="guaB"
                     /locus_tag="VXB18_000489"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0381742.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29210..30307)
                     /gene="recF"
                     /locus_tag="VXB18_000490"
     CDS             complement(29210..30307)
                     /gene="recF"
                     /locus_tag="VXB18_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0381743.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30310..30678)
                     /gene="yaaA"
                     /locus_tag="VXB18_000491"
     CDS             complement(30310..30678)
                     /gene="yaaA"
                     /locus_tag="VXB18_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0381744.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30837..32087
                     /locus_tag="VXB18_000492"
     CDS             30837..32087
                     /locus_tag="VXB18_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0381745.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32084..33367
                     /locus_tag="VXB18_000493"
     CDS             32084..33367
                     /locus_tag="VXB18_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0381746.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33409..34230
                     /locus_tag="VXB18_000494"
     CDS             33409..34230
                     /locus_tag="VXB18_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0381747.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34241..34786
                     /gene="pgsA"
                     /locus_tag="VXB18_000495"
     CDS             34241..34786
                     /gene="pgsA"
                     /locus_tag="VXB18_000495"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0381748.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34783..35610
                     /locus_tag="VXB18_000496"
     CDS             34783..35610
                     /locus_tag="VXB18_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0381749.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35595..36434
                     /locus_tag="VXB18_000497"
     CDS             35595..36434
                     /locus_tag="VXB18_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0381750.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPVKIEEFKES
                     LNG"
     gene            36427..37221
                     /locus_tag="VXB18_000498"
     CDS             36427..37221
                     /locus_tag="VXB18_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0381751.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37280..38098
                     /gene="mreC"
                     /locus_tag="VXB18_000499"
     CDS             37280..38098
                     /gene="mreC"
                     /locus_tag="VXB18_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0381752.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38098..38592
                     /gene="mreD"
                     /locus_tag="VXB18_000500"
     CDS             38098..38592
                     /gene="mreD"
                     /locus_tag="VXB18_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0381753.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38686..39864
                     /locus_tag="VXB18_000501"
     CDS             38686..39864
                     /locus_tag="VXB18_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0381754.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40088..40867
                     /gene="rpsB"
                     /locus_tag="VXB18_000502"
     CDS             40088..40867
                     /gene="rpsB"
                     /locus_tag="VXB18_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0381755.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            40933..41973
                     /locus_tag="VXB18_000503"
     CDS             40933..41973
                     /locus_tag="VXB18_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0381756.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(42094..43020)
                     /gene="cysK"
                     /locus_tag="VXB18_000504"
     CDS             complement(42094..43020)
                     /gene="cysK"
                     /locus_tag="VXB18_000504"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0381757.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(43305..43940)
                     /locus_tag="VXB18_000505"
     CDS             complement(43305..43940)
                     /locus_tag="VXB18_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0381758.1"
                     /translation="MEFRIIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            43996..45294
                     /locus_tag="VXB18_000506"
     CDS             43996..45294
                     /locus_tag="VXB18_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0381759.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            45291..45953
                     /locus_tag="VXB18_000507"
     CDS             45291..45953
                     /locus_tag="VXB18_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0381760.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            46033..46581
                     /gene="raiA"
                     /locus_tag="VXB18_000508"
     CDS             46033..46581
                     /gene="raiA"
                     /locus_tag="VXB18_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0381761.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            46717..48690
                     /locus_tag="VXB18_000509"
     CDS             46717..48690
                     /locus_tag="VXB18_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0381762.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNIQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            48687..49139
                     /gene="rplI"
                     /locus_tag="VXB18_000510"
     CDS             48687..49139
                     /gene="rplI"
                     /locus_tag="VXB18_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0381763.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            49183..50535
                     /gene="dnaB"
                     /locus_tag="VXB18_000511"
     CDS             49183..50535
                     /gene="dnaB"
                     /locus_tag="VXB18_000511"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0381764.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            50537..50803
                     /locus_tag="VXB18_000512"
     CDS             50537..50803
                     /locus_tag="VXB18_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381765.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            50892..52238
                     /gene="cbpD"
                     /locus_tag="VXB18_000513"
     CDS             50892..52238
                     /gene="cbpD"
                     /locus_tag="VXB18_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0381766.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      52321..52423
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            52494..52784
                     /locus_tag="VXB18_000514"
     CDS             52494..52784
                     /locus_tag="VXB18_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0381767.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            52747..53505
                     /locus_tag="VXB18_000515"
     CDS             52747..53505
                     /locus_tag="VXB18_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381768.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            53543..54550
                     /locus_tag="VXB18_000516"
     CDS             53543..54550
                     /locus_tag="VXB18_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0381769.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            54550..55278
                     /locus_tag="VXB18_000517"
     CDS             54550..55278
                     /locus_tag="VXB18_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381770.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            55397..55855
                     /locus_tag="VXB18_000518"
     CDS             55397..55855
                     /locus_tag="VXB18_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0381771.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            55857..58289
                     /locus_tag="VXB18_000519"
     CDS             55857..58289
                     /locus_tag="VXB18_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0381772.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            58610..59263
                     /gene="rr06"
                     /locus_tag="VXB18_000520"
     CDS             58610..59263
                     /gene="rr06"
                     /locus_tag="VXB18_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0381773.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            59260..60600
                     /gene="hk06"
                     /locus_tag="VXB18_000521"
     CDS             59260..60600
                     /gene="hk06"
                     /locus_tag="VXB18_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0381774.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGG
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            60683..61210
                     /locus_tag="VXB18_000522"
     CDS             60683..61210
                     /locus_tag="VXB18_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0381775.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            61310..61441
                     /locus_tag="VXB18_000523"
                     /pseudo
     CDS             61310..61441
                     /locus_tag="VXB18_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            61488..>63127
                     /gene="pspC"
                     /locus_tag="VXB18_000524"
     CDS             61488..>63127
                     /gene="pspC"
                     /locus_tag="VXB18_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0381776.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVGGRN
                     TPTVTSSGQDISKKYADEVKSHLEEMLSGIQLDRRKHTQNFNFNLKLSKIQTKYLREL
                     SVLKSKSELTLETKEELLSKTKAELDAAFEQFKKDTLKLGEKVAEAEKKVEEAKKKAK
                     AQKEEDHRNYPTNTYKTLELEIAESDVKVKEAELELLKEEAQTRNEDTINQAKAKVKS
                     EQAEATRLKKIKTDREEAEATRLKKIKTDREEAEEEVKDKPKKRTKRGALGEPATPDK
                     KENDAKSSDSSVGEETLPSPSLKPGKKVAEAEKKVAEAEKKAKAQKEEDRRNYPTNTY
                     KTLELEIAESDVEVKKAELELVKEEAKKPLNEGTIKQAKAEVESKKAEATRLEKIKTD
                     RKKAEEEAKRRAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPVPAPKPEKPAEQPK
                     AEKTDDQQAEEDYARRSEEEYNRLTQQQPQKPEQPAPAPKIGWKQENGMWYFYNTDGS
                     MATGWLQYNGSWYYLNSNGAMATGWLQNNGSWYYLNANG"
BASE COUNT        19845 a        10719 c        12552 g        20011 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga gtttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaagca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 tgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacggccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 cttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgttccttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcataatc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa gtccaaagga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctt
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca cattaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 aacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gccagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atagaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctag cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacattttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataggagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatac tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aatcccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattc cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt gctaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccaacttttc atctgacaaa cccaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt agcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttgaacatca aatacaagct ccattaattc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 agtcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgatttg accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctcc
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tgtcaacttt gttgtaaaga
     6901 taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gataaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caatattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt cgatccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttga tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggaa tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcacgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagttcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccctctat taagtttaca gattctttac agatatttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaaa aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagagt ctgcatgact ttgtttttgg
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gatatttcaa aaatatctaa aatatctcct cgaagactaa attcgccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgatcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga tataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacatcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatatac
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctacacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttctgaa accacatcct cgtccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccgtct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaattaatt ccagattaat
    10741 tgtatcaata tctgcaagtg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cttctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 cgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 taggcgttca tctggaactt ccaccattcc aacatttgga tcaatagtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag tcgacttgat tgtacaagcg tgtgattttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatta acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgaaatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt catatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcaa ctttttttcc gctgagtgac tggatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagttataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgatgagt
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa tcaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaactacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat cttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttctcca ggtactttag tcccatctga caatcgaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaactgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 cgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacctataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt ctctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcata agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctaa aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gggataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaaggttt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca agctaatcaa gtattaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagctgtta ctagcaaatt agttcctgcc
    21061 agtcagttga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacac aaaaatcttc tagattgaca
    21181 gcaggagttg ataaattaca atcaggatct gggcaattag cagacaaatc cagtcagtta
    21241 ctttcaggtg cttcttcatt agagaatgga gctaataaat tggcagatgg atctgggaaa
    21301 ctagcagaag gtggaacaaa gttaacttct ggattggaag atttacagac aggacttgct
    21361 tctttaggac aaggactagg taatgctagt gatcaactca aatcagtatc aacagaatct
    21421 aaaaatgcag agattttgtc aaatccactc aatctttcaa aaagcagaca atgatcaagt
    21481 tcttgtaaat ggaatcgcaa tagctcctta tatgatatca gttgctcttt ttgttgcagc
    21541 aatatcaaca aatatgatat tttcgaaatt gccttcagga cgtcatccag agatccgttg
    21601 ggcttggttg aaatctcgag ctgaaataaa tggtattata gctgttttgg caggaatttt
    21661 ggtatatgga ggagttcatc ttattggttt aactgctaat catgagatga gaatatttat
    21721 tctcatcatc ctaacaagtt tagtattcat gtctatggtg accactttaa caacgtggaa
    21781 tagccgtata ggagctttct tctcacttat tttgctttta ctacagttag catcaagtgc
    21841 aggtacttat ccacttgctt tgacaaatga tttctttaaa tctattaatc cctggttacc
    21901 aatgagctat tcagtttcgg gattacgaca aacaatctcc atcaacaagt cattttccta
    21961 gctgtcatac tagctctatt tactggttta ggtatactag cctatcaaca taagaaaatg
    22021 gaagaagatt aaaaaaatcg accgattaac tggtcgattt tttatgcctt agatgacttt
    22081 cgtctgtgat tatagattcc aaatagtaag agagaagtaa aggaacagat tgctccagta
    22141 ataaaaccat tgggaatgaa ggaaagtgta atagttcctt tccccttggg aatgtcaact
    22201 ttcataaatc cagtttgagc ttgtttaatt tctattttct taccatcttg gtaggcagac
    22261 caacctttgt cataaggaat ggtgaagaaa atagatgtat cttgttggac atcatatgta
    22321 gcaaaaacct tgtttttaga agttgatact gtgacaggtt gttctttaat tttttgaatt
    22381 gccttggtga aagttttggt atctaaacga tagaaggtag gagattcaaa tgatacttgt
    22441 gaatttccag ggaaactaac attgatattg aaagtttttt tctctttagt atatcctaga
    22501 ttaaagaagg agaagacatt atcagttgta aaagtctttt tttcaccatt tacaaggatg
    22561 tcaaccttct tttgtttatc gttagaaaag tgaaggttta tgaaagagag ataaacttgg
    22621 ctgttttctg gaacttcaat ttgatactgg attgctgcat cttcatttga agaacttgtg
    22681 acactaatca aatcattagt attttctatt ttttctgttt tttcataagg tattggagaa
    22741 aaataatcaa aattgacgtt agcaagttga tttaaaaatg aggcctgatt atccaaggta
    22801 tgttcattga acttgacatc attgtaaaca gattgactag caactgcaat cggaagagag
    22861 tattgatttt catatagggt aagattatct ttttgataga tatctttaaa gccatactta
    22921 tcaataggac tgtctgagat attgtactgg ataccaaata aactatcagc caaaatacta
    22981 ttatttgcat atcggagatt gagattagtc ccagaggatt taaaaccaag tttatctaaa
    23041 gtagagcttg atgaacgatt tcgaacagat gaaaattgag agattccatt gtagttgaat
    23101 ttcatactgt catttcctgt ctgagtttgt agtttttcag tacgagtaaa ttgatttcca
    23161 atatatgttg agaaagattc catagctggg atatctcgac tataagcact tcgagaagca
    23221 aatccccatt ccttagcaat tccgtccatt tgagatgaag catttaaact catttcaacc
    23281 agtataaata aagagattag aatggcaaat agattcacag atataaactt tttgataact
    23341 gcaaggagta aaagagaata gacaaccaaa aattcaagag taagcagaat attcaaatct
    23401 gttaaaaaag aataatgcga ttttagatag atggtagcta aaaatcctgt tactacaaga
    23461 aaaagcgaaa ctaaaaaatt ccagacttta agttctttca gacgctttaa gacttctgct
    23521 gctgtgtaaa ttaacaaggt agagaaaatc caagcatagc gatgtaaaaa catgtttgga
    23581 gtatgcatgc cttgccaaaa taagtcaaga gcttctatgt aaaagcttgc aattagaaat
    23641 gcaaagaata ttacatatat gagtttcacg tgaaacttaa tagatttcag cgtaaaaaat
    23701 aaaatggtca aaataaaggg aaatagtcca acaaaaatca ttgggatggc cccatacttt
    23761 gttgtgtcaa aggaaccaat gaattgctta gcaaagagat caagatacca gctactttca
    23821 gtttgaaact ttgtaacttc agtcaatttt tccccatgtg tctgtaaatc aaatagagtg
    23881 ggaagagtca taatcaaact agccatacca gctaaaaagg agataactat gaaatcaaga
    23941 acagatgatt ttcgagtctt aaagtcccac gaaatttgac agagatacca gaaaataaga
    24001 aacaatactg tcatatatcc aaaataataa ttttgaataa ataagattga cagacttgta
    24061 aagtacaata ggagtttctt ttcagttatc agtagatgta aaccagttat aattaaagga
    24121 atcaagataa aaacatctag ccaggttttt atctctaatt gactgacagt gaaactcatc
    24181 agagcatagg aagtagataa ggctagtttt aaagtctgag ggatagattg aaacaattta
    24241 ttcaaactaa aaaaggttga cagaccaatc aatccaaatt ttaagagagt ggtcagatag
    24301 acagcatctg gcatgttcgt tagatcaaaa aagtaaacta gaggcgcgag aaaactaccc
    24361 aagtaataac tagatagggc atagaagttt agccctagac cacttgtaaa ggtgtaaaac
    24421 agactactat ttccatgtag gatatttcgt aaggctacat caaaaataac gtattgatga
    24481 aagccatctc ctaatagagg agagttgtcg ctattccagt agataccttg agatagatat
    24541 actccagaca taatcactac aggaatgatg agagaaataa aataggttcg atatgttttt
    24601 aaaaatgatt tcatgttacc tcgtagaatg atagaaaact cagttggtta acccaactga
    24661 gttttgaagt tttatttagt ctttccaaag ttctttaact tttgcttgta cttctgcatt
    24721 ttctaggaat tcatcgtagg tttcatcgat acggtcaatg acgccatttt tagataagac
    24781 aatgatatgg ttagccaaag tttgaataaa ttcgtggtca tggctagcaa agatgattga
    24841 ttctttaaag tttttcaatc catcattcaa gcttgagata gattccaagt ccaagtgatt
    24901 tgttggatca tcaagtacaa ggacatttga ttttaagagc atgagttttg aaagcatgac
    24961 acgaactttt tctccccctg acaagacatt tacaggtttg ttaacttcat ctccagagaa
    25021 gagcatacgg ccgaggaagc cacgtaggaa agtattgtca tcttcttctt tacttgcgaa
    25081 ttgacgcaac cagtcaagaa ttgattctcc tcctgcaaaa tcagctgagt tatcttttgg
    25141 taggtaagat tgactagttg taactcccca cttgacagtt ccttcatagt caatatctcc
    25201 catgattgca cgaattaatg cagtcgtttg aatatcattt tgtccaataa gtgctgtctt
    25261 atcatctgga cgcaagatga aactaatatt atccaagata gtttcaccat caatctttac
    25321 agttagattt tctactgtca agagatcatt accaatctca cgttccgctt taaagttgat
    25381 aaatggatat ttacgactag atggtacaat ctcttctagc tcaatcttat caagcatttt
    25441 cttacgtgat gttgcctgcc ttgacttaga agcattggca gagaaacgag caacgaattc
    25501 ttgcaattgt ttaatttttt cttctgcttt agcattacgg tctgctagca atttagcagc
    25561 aagctcagaa gattccttcc agaagtcgta gtttccgaca tagagtttga tttttccaaa
    25621 gtcaaggtcg gccatgtgag tacaaacttt gtttaagaag tgacggtcgt gggatactac
    25681 gataactgtg ttatcaaagt caatcaagaa gtcttctaac caagtaatcg attggatatc
    25741 caaaccgtta gtaggctcgt ccaagagaag aacatctggt ttaccaaaaa gtgctttggc
    25801 gaggagaacc tttacttttt caccgttggc caattcgctc atgttttggt agtgtaattc
    25861 ttctggaatg tttaggtttt gaagtagttg agaggcttca ctctctgctt cccaacctcc
    25921 aagttcggca aactctcctt cgagttcggc agcacgaacc ccgtcctcgt ctgagaaatc
    25981 ttccttcatg tagatagcat ctttctcttt catgatgcta taaagttttt catttcccat
    26041 gataacgaca tcaatggcac gttcatcttc gtagtcaaag tgattttgac gaagaacaga
    26101 gagacgttca tctggaccaa gagagatgtg accagtagta ggttcgatat ctccagctaa
    26161 aatttttaaa aaggttgatt ttccggcacc attagcaccg attaatccgt aagtatttcc
    26221 ttctgtaaat ttgatattga catcatcaaa aagtttgcga tcactaaaac gtagtgaaac
    26281 atcagatact gtaagcaata tttttctcct atatgtgtaa tatatttatt ctactagaaa
    26341 atacagaaat attcaaattt ttatttgtca attttgtgta aattatattt acagtatcct
    26401 ttacacaaat ctgtaaaaag caaggctgat ttattttgat aaattacggt tatttcatta
    26461 aaaaaatgct ataattgaaa ggactatatc gaaggagaac aaaatgacta aacccattat
    26521 tttaacagga gaccgtccaa caggaaaatt gcatattgga cattatgttg gaagtctcaa
    26581 aaatcgagta ttattacagg aagaggataa gtatgatatg tttgtgttct tggctgacca
    26641 acaagccttg acagatcatg ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt
    26701 ggctttggat tatcttgcag ttggattgga tccaaataag tcaactattt ttattcaaag
    26761 ccagattcca gagttggctg agttgtctat gtattatatg aatctagttt cgttagcacg
    26821 tttggagcga aatccaacag tcaagacaga gatttctcag aaaggatttg gagaaagcat
    26881 tccgacagga ttcttggtct atccaatcgc tcaagcagct gatatcacag ctttcaaggc
    26941 taattatgtt cctgttggga cagatcagaa accaatgatt gagcaaactc gtgaaattgt
    27001 tcgttctttt aacaatgcat ataactgtga tgtcttggta gagccggaag gtatttatcc
    27061 agaaaatgag agagcagggc gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc
    27121 actaaataat ggtatttatt tagctgatga tgcggatact ttgcgtaaaa aagtaatgag
    27181 tatgtataca gatccagatc atatccgcgt tgaggatcca ggtaagattg agggaaatat
    27241 ggttttccat tatctagatg tttttggtcg tccagaagat gctcaagaaa ttgctgatat
    27301 gaaagaacgt tatcaacgag gtggtcttgg tgatgtgaag accaagcgtt atctacttga
    27361 aatattagaa cgtgaactgg gtcctattcg tgagcgccgt attgaatttg ctaaggatat
    27421 gggagaagtt tataatatga ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca
    27481 aaccctatct gaggtaaaag gggcaatggg acttcattac tttaactaag tttattttac
    27541 aagaaactat catttctatc tcgaagaaaa gatagttttt tatttacccc tgtaacattt
    27601 gacaaatttt tatagaatgg tatgatagat acaatataaa aagagtcaag ctcaaaaaga
    27661 aagaaaagag gaaacttcga atgtctaatt gggacactaa atttttgaaa aaaggtttta
    27721 cctttgatga tgtattgctt attccagctg aaagtcatgt gttgcctaac gatgcagatt
    27781 taacaactaa attggcagat aatttgactt taaatatccc aattattacc gctgccatgg
    27841 acacagttac agagagtcaa atggccattg ctattgctcg tgcaggtggt ctcggagtta
    27901 tccataaaaa catgtcaatt gctcaacaag cagacgaggt tcgtaaggta aaacgttctg
    27961 aaaatggagt tattattgat ccgttcttct tgacgcctga acatacaatt gctgaagcag
    28021 atgagcttat gggtcgttac cgcatcagtg gtgttccagt tgttgaaaca cttgaaaatc
    28081 gtaaattggt tggtattttg acaaaccgag atcttcgttt tatttcagat tataatcaac
    28141 caatttcaaa ccatatgact agtgaaaatc ttgttactgc tcctgtgggt acggatcttg
    28201 caacggctga gagtattctt caagagcatc gtattgaaaa acttccgttg gtcgatgaag
    28261 aaggcagtct ttctggtttg atcactatca aagatattga aaaagttatt gagtttccaa
    28321 atgcggctaa agatgaattt ggtcgtcttc tagttgcagg tgcagtaggt gttacttcag
    28381 atacatttga acgtgcagag gctctttttg aggcaggagc ggatgcgatt gttattgata
    28441 ctgcacatgg tcattctgca ggtgtcttgc gtaaaattgc cgagattcgt gctcatttcc
    28501 cagatcggac tttgattgct ggaaatattg ctactgctga aggtgcacgt gccctttatg
    28561 aagcgggtgt agacgttgtt aaggttggta ttggaccagg ttctatctgt actactcgtg
    28621 tgattgctgg tgttggtgtt ccgcaagtaa cagctatcta cgatgctgca gctgttgcgc
    28681 gcgaatatgg taaaacgatt attgctgacg gtgggatcaa gtattctgga gatattgtaa
    28741 aagcacttgc tgcaggtgga aatgctgtta tgcttggatc tatgtttgct ggaactgatg
    28801 aagctccagg cgaaactgaa atcttccaag gacgtaaatt caagacttac cgtggtatgg
    28861 gatcaattgc tgctatgaag aaaggttcaa gcgaccgtta tttccaaggt tctgtcaatg
    28921 aagcaaacaa gctcgttcca gaaggaattg aaggtcgtgt tgcttataaa ggagcggcag
    28981 ctgatattgt tttccaaatg attggtggta ttcgctctgg tatgggttac tgtggtgcag
    29041 ctaaccttaa agaactacac gataatgctc aatttattga aatgtctggt gctggtttga
    29101 aagaaagcca tcctcatgat gtgcaaatta ctaatgaggc accaaattat tctatgtaaa
    29161 aaacaatgaa aagaactcca gtgaaaacag gagttctttt acaatgttgt caatttccat
    29221 ttacagaagc tttaccatcc tgaatagtga agatacttag attttctggc agattttgaa
    29281 gatggtctaa gcttgttgtt gtgataaagg tttggattga ttgagaaatc gtttctaata
    29341 attttaactg tctagtgttg tcaagttcac tcatcacatc gtcaagcagt aatataggag
    29401 attctgtggt aatgctttcc attaattcga tttctgctaa ttttatcgag aggacgagac
    29461 tacgatgttg accttggctt ccgaaactag catccatccc atttatataa aaagaaatgt
    29521 catctcgatg aggaccgaca ccagtattct ttttaaataa atctctggat ctactttttt
    29581 ctaaagcaat tttgaaagat tcggataagt tttgtttgtc agttatattg acagaagatt
    29641 gataggatat tgacaactct tcgatctgat tagagagttc aaaatgtttc ttacgcccaa
    29701 atgattctag tttttttatg aaatctaagc ggtgattcat tacacgacat ccataatcaa
    29761 ctagctgatc atctaacaca gaaaggaatg tttcatctat tttttgagct gattttaggt
    29821 aagtgtttct ttgctttagg atgtggttat aattggttaa gtcagataaa tagattggct
    29881 taatttgccc aagttccata tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta
    29941 gttgtaaatc ttcaggagca aataagacaa cattcatgtg tcctacataa tctgaaaggc
    30001 gtgcctgttt taagtgatta acttttgtta cacggccttt ttgtgttagt tcgatttcta
    30061 ggggaatgga tccagttttt ttctgaacga gacctgaaag atgaagttgt tcctcatcaa
    30121 aatgaatgag atttttatct gttcgagttc gatgactacg cgttaaggct aaaaaataga
    30181 tagcctctaa catgtttgtt tttccttgtg cattacgtcc caaaaagaca ttcaatttag
    30241 gattaaagtc tattttcgtt tctttgtaat tacgaaaagt cttgagagat agatgttgta
    30301 gccacatgat tatctaccag ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg
    30361 tttcgatttg tcttttttaa ctcccttatt catctttttg acaagtttag cgatccgttc
    30421 tttttcaact ttatcagctt ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa
    30481 gatgtcaatg ttcatgtcag ggatgtcaac tttatcgcca atacgaagtt tttttccacg
    30541 acgactctct aattccctat taaagtaaac agaatgttca gagagaaatg atttaatagc
    30601 tcctccgcta tgtgtaattc caagttcttt gagtagtgct tggagggtaa taaattcttc
    30661 aaataatttg tattccataa ttcacctcaa tctttggtat tataccatat tttcctaaaa
    30721 atagtgagag agacagcgag aaatgtaagc gatttttatt tcaaaagtgt tacagggaac
    30781 aagaaaattt caggttttcg tgatataata gaagtctgta tataaggagg taaatcatgg
    30841 agttagtgca tggaatttca acacatttta tccaatcaaa aaagtttaaa acaaacaaaa
    30901 ttaccgtgcg ttttaccgct ccattatccc ttgatacgat tgcaggtcac atgttgagtg
    30961 caagtatgct agagactgct aatcagatgt accccacttc tcaagatttg aggagacact
    31021 tggccagtct atacggtaca gatatgtcaa ccaattgttt cagaagaggg caaagccaca
    31081 ttatagaatt gacatttacc tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa
    31141 cctctcagat tttggaactt gtaaaagaaa ctcttttttc acccgcagta gttgataatg
    31201 ggtttgatcc ggccttattt gaaattgaga aaaaacaatt gctagcaagt ttagcagctg
    31261 atatggatga ttctttttat tttgcacata aagaattgga taaattgttt tttcatgatg
    31321 aacgtcttca attggaatat agtgatttac gaaatcgtat tttagctgaa actccacaaa
    31381 gttcttattc ttgtttccaa gaatttttag ccaatgatcg aatagatttc tttttcctag
    31441 gtgattttaa tgaggttgaa attcaaaatg tattagaatc atttggcttt aaaggtcgaa
    31501 aaggagatgt gaaggttcag tattgtcaac cttattctaa tatccttcag gaaggtatgg
    31561 ttcggaaaaa tgtgggacaa tccattttgg aattaggtta tcattaccgt tctaaatatg
    31621 gtgatgagca acatttaccc atgattgtaa tgaatggttt acttggtgga tttgctcact
    31681 ctaagctctt tacaaatgtc cgtgaaaatg ctggattagc ttataccatt tcaagtgagc
    31741 ttgatttatt tagtggattc ttgaggatgt atgctggtat caatcgagaa aatcgtaacc
    31801 aggctcgtaa aatgatgaat aatcaactgc ttgatttaaa aaaaggttat tttacagagt
    31861 ttgagttaaa tcagaccaag gaaatgattc gttggtcgtt gttactttct caagataatc
    31921 aatcttcatt gattgaacgt gcttatcaaa atgccttatt tggaaaatct tcagcagact
    31981 ttaaaagttg gattgcaaag cttgaacaaa ttgacaaaga tgctatttgt agagtagcta
    32041 ataatgtgaa actacaagcg atttacttta tggaaggaat agaatgacaa aggttgtttt
    32101 tgaagaaaaa tactatccag ctgtaaaaga aaaggtttat cgaactcgtt tggccaacgg
    32161 attgacagtt gctcttttgc ctaaaaagga atttaaagag gtttacggga gtgtcactgt
    32221 acagtttggt tcggtagata cgtttgtcac agaagttgac ggatatgtaa aacaatatcc
    32281 tggaggaatt gctcattttc ttgaacataa attatttgag agagaagatt ctagtgattt
    32341 gatgtcggct tttacgagtc taggtgcaga tagtaatgcc tttacaagct ttacaaaaac
    32401 aaactatctt ttttcagcaa cggattattt tttagaaaat ttagatttac ttgatgaatt
    32461 ggtaacatca gcacacttta ctgaagcttc cattctgaca gagcaggata ttattcagca
    32521 agaacgagaa atgtaccaag atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa
    32581 tttgtatcct ggtacacctt tagcaactga tatagttgga agtgaggagt ccatttccca
    32641 aatcaatcta actaatttgc aagaaaattt tacaaagttt tacaaacctg taaacatgtc
    32701 tctgttttta gttggtaatt ttgatgtgga gcgagtacag gactattttg aaagcaaaga
    32761 actgaaagat tcagattttc aggaagtagc aagagaaaag ttgtttttac agcctgtaaa
    32821 gccaacagat agtatgagaa tggaagtatc ttctcccaaa ctagcgattg gagttagagg
    32881 taagcgagaa gtttctgaag cggattgcta tcgacatcat attttattaa aattattgtt
    32941 tgcaatgatg tttggttgga cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat
    33001 tgatgcgtcc ttatctctgg aagttgaaat aacaagtcgc tttcattttg tcatgttgac
    33061 aatagatacg aaagagccag ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt
    33121 tacaaaggat ttagatatta cagaggaaca tttagatatt atcaaaagag agatgtttgg
    33181 cgaatttttc agtagcatga actctcttga atttattgca acgcaatatg atgcttttga
    33241 aaatggtgag acaatttttg atttgccgaa aattttacag gaaattactt tagaggatgt
    33301 ccttgatgct ggacatcatt taatagatga tggtgacata gttgatttta caatattccc
    33361 atcgtagtaa cctatcataa tagacactag aaagaaggga tgacaagtat gagaaaaaaa
    33421 acaattggag aggttttacg attagctaga atcaatcagg gattgagttt agatgaattg
    33481 cagaaaaaga cagaaatcca gttagatatg ttggaagcaa tggaagcaga cgatttcgat
    33541 caacttccaa gtccttttta cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag
    33601 ttagatgacc aaattgtttt ggatgcttat gattctggga gtatgattac ttatgaggaa
    33661 gtagatgttg atgaagatga gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa
    33721 aaaacatcat ttttaccttt attttatttt atcctttttg ctttatcgat tttaattttt
    33781 gtgacttatt atgtttggaa ctatattcaa actcaaccag aggagccttc tctttctaat
    33841 tacagtgtgg ttcaatcaac aagttcaact agctctgttc cccactcctc aagtagtagt
    33901 tcttctagta tagaatcagc tataagtgta tcaggcgaag gaaatcatgt agaaatcgct
    33961 tataagacaa gtaaggaaac agttaaattg caattggcag tttcagatgt tacaagttgg
    34021 gtcagtgttt cagaaagcga acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt
    34081 gcagaagcaa cagttgcaac taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt
    34141 gttgatttga cagtagataa tcagactgtt gatttatcga aattaacagc tcagactgga
    34201 caaatcactg taacctttac taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc
    34261 caatctctta acaataggtc gaattctctt tatacctatt tttatcttta ttttaacgat
    34321 aggaaattcg atagagagtc atatagttgc agctattatc tttgctgttg ccagtattac
    34381 cgactattta gatggatatt tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt
    34441 tgcagatcct atggcggata agttactagt tatgtcggct tttattatgt tgattgagtt
    34501 aggtatggct ccggcttgga ttgttgcagt gattatctgt cgtgagttag ctgtgacagg
    34561 tttaaggctt ttattggttg aaactggtgg aacaatttta gcagcagcaa tgcctggaaa
    34621 aattaaaact tttagtcaga tgtttgctat tattttcttg ctattacatt ggactttgct
    34681 tggtcaagtt ctactttatg tagccttatt tttcactatc tactctggct atgactattt
    34741 caagggtagt gcctatgtat ttaaagggac atttggttcg aaatgaaatc aataattgat
    34801 gtaaaaaatc tttcttttcg ctataaagaa aatcagaact actacgatgt gaaggatatt
    34861 acgtttcacg tgaaacgtgg agaatggctt tcgattgtag ggcataatgg tagtggtaaa
    34921 tcaacgacgg ttcgattaat tgatggctta ctggaagcag aatccggaga gattgtaatt
    34981 gatggccaac gtttgactga ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt
    35041 tttcaaaatc cagacaatca atttgttgga gcgactgttg aagatgatgt tgcttttggt
    35101 ttggaaaatc agggactttc tcgtcaagaa atgaaaaaga gagtggaaga agctctggct
    35161 ttagttggca tgttggactt taaaaagaga gagccagcgc gtctatcagg tggccaaaag
    35221 caacgtgtgg ccattgcagg tgttgtagcc ctaagaccag ctattttaat cttagatgaa
    35281 gcaacgagta tgttggatcc tgaggggcgt agagaactta ttgggacagt aaaaggaatt
    35341 cgaaaagact atgatatgac ggtcatttct attacccatg atttggaaga agtcgccatg
    35401 agtgatcgcg tattggtcat gaaaaaaggg gaaattgaat caactagtag tccaagggag
    35461 cttttctctc gaaatgattt agatcaaatt ggattagacg atccttttgc taatcaatta
    35521 aaaaaatctt tgagccagaa tggctatgat ttacctgaaa attatttgac agaaagtgag
    35581 ctagaggata agctatggga attgctctag aaaatgtgaa ttttatatat caagaaggta
    35641 ctcccttagc ttcagcagct ttgtcggatg tttctttgac gattgaagat ggctcttata
    35701 cagctttaat tgggcacaca ggtagtggta aatcaactat tttacaactc ttaaatggtt
    35761 tattggtgcc aagtcaaggg agtgtgaggg tttttgatac cttaatcacc tcgacttcta
    35821 aaaataaaga tattcgtcaa attagaaaac aggttggctt ggtatttcag tttgctgaaa
    35881 atcagatttt tgaagaaacg gttttgaagg acgttgcttt tggaccgcaa aattttggag
    35941 tttctgaaga agatgctgtg aagactgcgc gtgagaaact ggctctggtt ggaattgatg
    36001 aatcactttt tgatcgtagt ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca
    36061 ttgcaggcat acttgccatg gagccagcta tattagtctt agatgagcca acagctggtc
    36121 tagatcctct agggagaaaa gagttgatga ccctgttcaa aaaactccac cagtcaggga
    36181 tgaccatcgt cttggtaacg catttgatgg atgatgttgc tgaatatgcg aatcaagtct
    36241 atgtaatgga aaagggacgt ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg
    36301 ttgtttttat ggaagaagtt cagttgggag tacctaaaat tacggccttt tgtaaacgat
    36361 tggctgatag aggcgtgtca tttaaacgat taccggttaa gatagaggag ttcaaggagt
    36421 cgctaaatgg atagtatgat tttggggcgt tatatcccag gggattcgat tgttcaccga
    36481 ttggatccac gtagcaaatt gcttgctatg atgctactga ttttgattgt gttttgggct
    36541 aataacccct tgacgaatct gattcttttt atagcgacag ggatatttat tgccttgtca
    36601 ggagtatctc tttcattttt tattcagggc ttgaagtcta tgtttttctt gattgccttc
    36661 acaactattt ttcaactatt tttcatttct aatgggaatg ttttatttga gttttcgttt
    36721 gtgagaatca cggattatgc tttgcaacaa gctgggatta ttttttgtcg ctttgtattg
    36781 attattttct tttcaacttt gttaacctta acaaccatgc ctttaagttt ggcatcagct
    36841 gtcgaagctt tattagcacc tttaaagcgt gtgaaagttc cagttcatga aattggattg
    36901 atgctgtcta tgagtttgcg ttttgtccca accttgatgg atgatacgac tcggattatg
    36961 aatgcacaga aagctcgtgg agtggatttt ggagaaggaa gcatcgttca aaaagtaaag
    37021 gcgatgattc ccattttgat tcctcttttt gcgacaagtt taaaacgtgc agattccttg
    37081 gctatcgcta tggaagcgcg tggctatcag ggtggaaaag gcagaagtca ataccgacaa
    37141 ttgaaatgga ctctaaagga tacgctgacc attcttgtta ttctcgtact tggttgttgt
    37201 ttatttttct taaaatctta gtagctttca ggaattgata aaaagttact gtaacagttt
    37261 ttgatataaa ggtagggata tgaaccgttt taaaaaatca aaatatgtca ttattgtttt
    37321 tgtcactgtt ctgcttgtgt cagctctctt agcgacgact tattcaagta caattgtgac
    37381 aaaattagga gatggaatct cattggttga tagagttgta caaaaacctt ttcagtggtt
    37441 tgattctgtc aaatcagatt tggctcattt gacacgaaca tataatgaaa atgaaagttt
    37501 gaagaaacag ctttaccaat tagaagttaa atcaaatgag gtggaaagtt taaagacaga
    37561 aaatgaacaa ctgcgccaat tgcttgatat gaagtctaaa ttgcaagcca caaagacttt
    37621 agcagcagat gttattatgc gttctccggt atcttggaag caggagttga ccttagatgc
    37681 aggtagatca aaaggtgctt ctgagaacat gttagctatt gcaaatggtg gcttgattgg
    37741 gagtgtttca aaagtagagg agaactctac tatagtcaac cttctgacaa atacggaaaa
    37801 tgctgataag atttctgtta aaattcaaca tggctctact acaatttatg gaattattat
    37861 tggctatgac aaggaaaatg acgttcttaa aattagccaa ttaaatagta atagcgatat
    37921 tagtgcggga gataaggtga ctactggtgg attaggaaac tttaacgttg ctgatattcc
    37981 tgttggtgaa gtggttgcca caacgcatag tacagactat ttgacacgag aagtaactgt
    38041 taaattgagt gcagatactc ataatgtaga tgtgatagaa ttagtgggga attcataatg
    38101 agacagttga agcgagttgg agtattttta ttgcttcctt tctttgttct aattgacgcc
    38161 catattagcc agcttctggg ctcatttttc ccccatgtac atttggctag tcattttctt
    38221 tttctatttc tcttatttga gacgatagaa gtatcagagt atctctacct agtctattgt
    38281 tttgttatag gcttggttta tgatgtttac tttttccatc taatagggat tacaactctc
    38341 ttatttatct tattgggagc cttccttcat aaattgaata gtgttatttt gttgaatcgt
    38401 tggacaagaa tgctagctat gattgtgctg acattcctgt ttgaaatggg tagttatctt
    38461 ttggctttta tggtagggtt gacagtagat agcatgtcga tttttatagt ctatagcttg
    38521 gtaccgacga tgattttaaa ttttttatgg attactgttt ttcaatttat ttttgaaaaa
    38581 tattatctat aagaacgaca tataaatgta acaaaggcgt aatatttatt aggccttttt
    38641 ttggtatact agtattgtct ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc
    38701 ttagcgtcac ttttattaag tacagtaatg gtttctcaag tagctgtttt aacaactgcg
    38761 catgcagaaa cgactgatga caaaattgct gctcaagata ataaaattag taacttaaca
    38821 gcacaacaac aagaagccca aaaacaagtt gaccaaattc aggagcaagt atcagctatt
    38881 caagctgagc agtctaactt gcaagctgaa aatgatagat tacaagcaga atctaagaaa
    38941 ctcgagggtg agattacaga actttctaaa aacattgttt ctcgtaacca atcgttggaa
    39001 aaacaagctc gtagtgctca aacaaatgga gccgtaacta gctatatcaa taccattgta
    39061 aactcaaaat caattacaga agctatttca cgtgttgctg caatgagtga aatcgtatct
    39121 gcaaacaaca aaatgttaga acaacaaaag gcagataaaa aagctatttc tgaaaaacaa
    39181 gtagcaaata atgatgctat caatactgta attgctaatc aacaaaaatt ggctgatgat
    39241 gctcaagcat tgactacgaa acaggcagaa ctaaaagctg ctgaattaag tcttgctgct
    39301 gagaaagcga cagctgaagg ggaaaaagca agtctattag agcaaaaagc agcagctgag
    39361 gcagaggctc gtgcagctgc ggtagcagaa gcagcttata aagaaaaacg agctagccaa
    39421 caacaatcag tacttgcttc agcaaacact aacttaacag ctcaagtgca agcagtatct
    39481 gaatctgcag cagcacctgt ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca
    39541 agttatccaa ttggagaatg tacatgggga gtaaaaacat tggcaccttg ggctggagac
    39601 tactggggta atggagcaca gtgggctaca agtgcagcag cagcaggttt ccgtacaggt
    39661 tcaacacctc aagttggagc aattgcatgt tggaatgatg gtggatatgg tcacgtagcg
    39721 gttgttacag ctgttgaatc aacaacacgt atccaagtat cagaatcaaa ttatgcaggt
    39781 aatcgtacaa ttggaaatca ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt
    39841 gttacatata tttatgcaga ttaatttaca gagggactcg aatagagccc tcttttcagg
    39901 ttttaccgtg acaatcccta ttaaaaatta tatcaaaata gcttgaaaat attggaaaag
    39961 tatggtagaa tgaaaattgt cgtgtgaacg ataatactca ttcttgatga attgtgaagc
    40021 agttgccctt gggtcgtttt gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga
    40081 aatactcatg gcagtaattt caatgaaaca acttcttgag gctggtgtac actttggtca
    40141 ccaaactcgt cgctggaatc ctaagatggc taagtacatc tttactgaac gtaacggaat
    40201 ccacgttatc gacttgcaac aaactgtaaa atacgctgac caagcatacg acttcatgcg
    40261 tgatgcagca gctaacgatg cagttgtatt gttcgttggt actaagaaac aagcagctga
    40321 tgcagttgct gaagaagcag tacgttcagg tcaatacttc atcaaccacc gttggttggg
    40381 tggaactctt acaaactggg gaacaatcca aaaacgtatc gctcgtttga aagaaattaa
    40441 acgtatggaa gaagatggaa ctttcgaagt tcttcctaag aaagaagttg cacttcttaa
    40501 caaacaacgt gcgcgtcttg aaaaattctt gggcggtatc gaagatatgc ctcgtatccc
    40561 agatgtgatg tacgtagttg acccacataa agagcaaatc gctgtcaaag aagctaaaaa
    40621 attgggaatc ccagttgtag cgatggttga caccaatact gatccagatg atatcgatgt
    40681 aatcatccca gctaacgatg acgctatccg tgctgttaaa ttgatcacag ctaaattggc
    40741 tgacgctatt atcgaaggac gtcaaggtga ggatgcagta gcagttgaag cagaatttgc
    40801 agcttcagaa actcaagcag attcaattga agaaatcgtt gaagttgtag aaggtgacaa
    40861 caaatagtaa ttacctagga gggcggggct tagcccggct ctcctatttt caaaaaatat
    40921 aggagaatta aaatggcaga aattacagct aaacttgtaa aagagttgcg tgaaaaatct
    40981 ggtgccggtg ttatggacgc taaaaaagcg cttgtagaaa cagacggtga catcgaaaaa
    41041 gcgattgaat tgcttcgtga aaaaggtatg gctaaggcag ctaagaaagc tgaccgtgtt
    41101 gctgcagaag gtttgactgg tgtttatgtt aacggtaatg ttgcagcagt tattgaagta
    41161 aacgctgaaa ctgacttcgt tgcaaaaaac gctcaattcg ttgaattggt aaatactaca
    41221 gctaaagtca ttgctgaagg aaaacctgct aacaatgaag aagctcttgc tttgataatg
    41281 ccttcaggtg aaactcttga agctgcatac gtatctgcaa cagcaactat cggagagaaa
    41341 atctcattcc gtcgctttgc attgattgaa aaaacagacg cacaacactt tggagcatac
    41401 caacataacg gtggacgtat cggtgttatt tcagttgttg aaggtggaga cgaagcactt
    41461 gctaaacaat tgtcaatgca catcgcagcg atgaaaccaa cagttctttc ttacaaagaa
    41521 ttggatgagc aattcgttaa agatgagttg gcacaattga atcacgttat cgaccaagac
    41581 aacgaaagcc gtgcaatggt taataaacca gctcttccac acttgaagta tggatcaaaa
    41641 gctcaattaa ctgatgatgt tattgctcaa gctgaagctg acatcaaagc tgaattggct
    41701 gcagaaggca aaccagaaaa aatctgggac aaaattattc caggtaaaat ggatcgcttc
    41761 atgcttgata acactaaagt tgaccaagct tacacacttc ttgcacaagt ttacatcatg
    41821 gatgacagca agacagttga agcatacctt gaatcagtta acgcttcggt agttgagttt
    41881 gctcgctttg aagttggtga aggtatcgag aaagctgcaa acgacttcga agctgaagtt
    41941 gcagctacaa tggcagcagc cttgaataac taataataga aaggaagcaa attgcttcct
    42001 tttttgtatg cagtcgatcc ttatagggag agcttcctat tttcaaggta aaaataaaaa
    42061 gccctataat aagggccaat tgtatttagg agactaaact tcaaattcat agagtgctgt
    42121 agagagataa cgttcaccgt tatctggtgc tagagcaagg acttttttac ctgtacctaa
    42181 ttttttggca acctcgatgg ctccgtagat agctgcagct gaggaaatcc ctacaaggaa
    42241 gccttctttt ccaccaattt cacgtccgag tgcaagagca tcatctgatg ttacacgaac
    42301 gataccatca taggctttag tatcaagtgt atcaggaata aatccagctg agataccttg
    42361 aattttgtga ggaccaggtt tttcaccaga tagaatagca gattcatcag cttccactgc
    42421 ataaacttga atgttagaat tttctgattt gagtgcatga gaaacaccag aaatcgttcc
    42481 accggtacct actccagcaa caaaggcatc taatccatct ttaccgaaag cagctagtat
    42541 ctcagctcct gttgttcttt cgtgtacttc tggattagct ggattgtcaa attgaagagg
    42601 aaggaaacca tcacgttcag cagcgatttc ttgagcctta gcaatagcac ctttcattcc
    42661 ctcgctacca ggagttagga cgagttcagc accataagct tggataattt tacgtcgttc
    42721 tacactcata gtttcaggca taacgatgac gactttatac cctttagcag cacctaccca
    42781 tgaaagtcca ataccagtgt ttccacttgt tgcttcaaca atagtagaac caggtttcag
    42841 aataccatct tgttcagctt tttcaatcat gctaagggca atacggtctt ttacagatga
    42901 accaggatta aatgcttcaa gctttatata gacgtctgca gcaccttctg gcacgatgtt
    42961 gttaagttta acaatcggtg tttgaccgat taattcagta atgttgttat aaatagacat
    43021 atgaatacct ctttgtataa gatatcttta gtataacgct atctatacca tttgtaaaat
    43081 atagaaatcc tatcgaagcg ataggatttc tatatatcat agatcaaagt cattaatttt
    43141 caagtgattg cgttcagcta attctagtaa ataggtgtga aggaaaacga tatcaggttt
    43201 cgtttgaatt gcttcatttt ctagtatatt ttggtacgca tctttttatt ttgctcgcta
    43261 aagtagttgt gagaatgtca acgaaacgct gtattattca ttgtttacac taagtttaca
    43321 ggaacttcaa cctctcgtaa accttggtca gttaaagtga cttttccatt aaaaaactcc
    43381 acaagtgcag ctttaatagt ttctttttct tccttatcaa cataaatcat cgtatcgact
    43441 tgatctgtaa agtttgtatc cagctccatg agatcatgtt ctttaaggaa gttactgtac
    43501 tcttggtact gagcataaga catttgaata gcaatgccag cctgttcttt tatttcaata
    43561 ataccaattt ctttgacagc taaggcgaca ctgccggcgt aagcacgaat tagtcctcca
    43621 gcgcctagtt taataccacc aaagtagcgt gtcacgacca cacagacatt ggtgagattg
    43681 tgattttcta gtaccccaag catgggaaca ccagcagtac cactaggctc accatcatca
    43741 cttgtacgtt taatttcact acgttctcca ataataaagg cagagcagtt atgtgtcgct
    43801 ttgtagtgtt cttttttgat ggcagtaatg aagtcacgag cctcttcttc gctataaaca
    43861 cgcttggcat ggcagataaa gcgagatttt ttgatttctt cttggacttg gccgtcctct
    43921 ttaattatcc taaattccat gatttaattg tactaaaaaa taatctaaag tgctagtttt
    43981 tacgaataaa gaagtatgaa agtaaattta gattatctcg gtcgtttatt tactgagaat
    44041 gaattaacag aagaagaacg tcagttggcg gagaaacttc cagcaatgag aaaggagaag
    44101 gggaaacttt tctgtcaacg ttgtaatagt actattctag aagaatggta tttgcccatc
    44161 ggtgcttact attgtcgaga gtgcttgctg atgaagcgag tcagaagtga tcaaacttta
    44221 tactattttc cgcaggagga ttttccgaag caagatgttc tcaaatggcg cggccaatta
    44281 actccttttc aagagaaggt gtcagaggga ctgcttcaag cagtagacaa gcaaaagcca
    44341 accttagttc atgcggtaac aggagctgga aagacagaaa tgatttatca agtagtggct
    44401 aaagtgatca atgcgggtgg tgcagtgtgt ttggctagtc ctcgcataga tgtttgtttg
    44461 gagctgtaca agcgcctgca acaggatttt tcttgcggga tagctttgct acatggagaa
    44521 tcggaacctt attttcgaac accactagtt gttgcaacaa cccatcagtt attgaagttt
    44581 tatcaagctt ttgatttgct gatagtggat gaagtagatg cttttcctta tgttgataat
    44641 cccatgcttt accacgctgt caagaatagt gtaaaggaga atggattgag aatcttttta
    44701 acagcgactt cgaccaatga gttagataaa aaggtccgtt taggagaact aaaaagactg
    44761 aatttaccga gacggtttca tggaaatccg ttgattattc caaaaccaat ttggttatcg
    44821 gattttaatc gctacttaga caagaatcgt ttgtcaccaa agttaaagtc ctatattgag
    44881 aagcagagaa agacagctta tccgttactc atttttgctt cagaaattaa gaaaggggag
    44941 cagttagcag aaatcttaca ggagcaattt ccaaatgaga aaattggctt tgtatcttct
    45001 gtaacagagg atcgattaga gcaagtacaa gcttttcgag atggagaact gacaatactt
    45061 atcagtacga caatcttgga gcgtggagtt accttccctt gtgtggatgt tttcgtagta
    45121 gaggccaatc atcgtttgtt taccaagtct agtttgattc agattggtgg acgagttgga
    45181 cgaagcatgg atagaccgac aggagatttg cttttcttcc atgatgggtt aaatgcttca
    45241 atcaagaagg cgattaagga aattcagatg atgaataagg aggctggtct atgaagtgct
    45301 tgttatgtgg gcagactatg aagactgttt taacttttag tagtctctta cttctgagga
    45361 ataatgactc ttgtctttgt tcagactgtg attctacttt tgaaagaatt ggggaagaga
    45421 actgtccaaa ttgtatgaaa acagagttgt caacaaagtg tcaagattgt caactttggt
    45481 gtaaagaagg agttgaagtc agtcatagag cgatttttac ttacaatcaa gctatgaagg
    45541 attttttcag tcggtataag tttgatggag acttcctgtt aagaaaagtt ttcgcttcat
    45601 ttttaagtga ggagttgaaa aagtacaaag agtatcaatt tgttgtaatt cccctaagtc
    45661 ctgatagata tgctaacaga ggatttaatc aggttgaggg cttggtagag gcagcaggct
    45721 ttgagtatct ggatttatta gagaaaagag aagagagagc cagttcttct aaaaatcgtt
    45781 cagagcgctt ggggacagaa cttcctttct ttattaaaag tggagtcact attcctaaaa
    45841 aaatcttact tatagatgat atctatacta caggagcaac tataaatcgt gttaagaaac
    45901 tgttggaaga agctggtgct aaggatgtaa aaacattttc ccttgtaaga tgaggaaaaa
    45961 atttgcaaaa atagaatgaa agcgttataa taaaatcata aaaacaaaaa tgtttagaaa
    46021 gaaggtactc atatgattaa atatagtatc cgtggtgaaa acctagaagt aacagaagca
    46081 attcgtgatt atgtagtttc taaactcgaa aagatcgaaa agtacttcca accagaacaa
    46141 gagttggatg cccgaattaa cttaaaagtt tatcgtgaaa aaacggctaa agtggaagta
    46201 acgattccgc ttggatctat tactctccgc gcagaagatg tatctcaaga tatgtatggt
    46261 tcaattgacc ttgtaactga taaaattgaa cgtcagattc gtaaaaataa aacaaaaatc
    46321 gagcgtaaaa ataaaaataa ggtagcaact ggtcaattat ttacagatgc tttggtggaa
    46381 gattcaaatg ttgtccagtc taaagttgtt cgttcaaaac aaattgattt aaaaccaatg
    46441 gatttggaag aagcaattct acaaatggat ttattggggc atgatttctt tatctatgta
    46501 gatgttgaag atcagacaac caatgtgatt tatcgtcgtg aggatggtga aattggtttg
    46561 ttagaggtta aagaatctta atttcaatat gtgtaaaggt aggtttactg aattgtaaac
    46621 tacctttttc ttataattga tagaattact gattacactt ttaaaaagtc gctttttgag
    46681 gggtattatg gtataatggg tgccaagagg ttttgaatga aaaaatttta tgtaagtcca
    46741 atttttccta ttctagtagg attgattgcg tttggagtct tatccacttt cattattttt
    46801 gttaataata atctgttgac ggttttaatt ttgtttcttt ttgtaggagg ctatgttttt
    46861 ttatttaaga aactgagagt gcattataca aggagtgatg tagaacagat acagtatgta
    46921 aaccaccaag cggaagaaag tttgacatct ctattggaac agatgcctgt aggtgttatg
    46981 aaattgaatt tatcttctgg agaggttgag tggtttaatc cctatgctga attgattttg
    47041 accaaggaag atggtgattt tgatttggaa gctgttcaaa cgattatcaa ggcttcagta
    47101 ggaaatccgt ctacttatgc caagcttggt gagaagcgtt atgctgttca tatggatgct
    47161 tcttcaggtg ttttgtattt tgtagatgta tccagggaac aagccataac agatgaattg
    47221 gtaacaagtc gaccagtgat tgggattgtc tctgtggata attatgatga tttggaggat
    47281 gcaacttctg agtcagatat tagtcaaatc aatagttttg tagctaattt tatatcagag
    47341 ttttcagaaa aatacatgat gttttctcgt cgggtaagta tggatcgatt ttatctattt
    47401 actgactaca cggtgcttga gggcttgatg aatgataaat tttctgttat tgatgctttc
    47461 agagaagagt cgaaacagag acagttgccc ttgaccttaa gtatgggatt ttcttatggc
    47521 gatggaaatc atgatgagat agggaaagtt gctttgctca atttgaactt ggctgaagta
    47581 cgtggtggcg accaggtggt tgttaaggaa aacgacgaaa cgaaaaatcc agtttatttt
    47641 ggtggtgggt ctgctgcttc aatcaagcgt acacggactc gtacgcgcgc tatgatgaca
    47701 gctatttcag ataagattcg gagtgtagat caggtttttg tagtcggtca caaaaattta
    47761 gacatggatg ctttgggctc tgctgtaggt atgcagttgt tcgccagcaa tgtgattgaa
    47821 aatagctatg ctctttatga tgaagaacaa atgtctccag atattgaacg agctgtttca
    47881 ttcatagaaa aagaaggagt tacgaagttg ttgtctgtta aggatgcaat ggggatggtg
    47941 accaatcgtt ctttgttgat tcttgtagac cattcaaaga cagccttaac attatcaaaa
    48001 gaattttatg atttatttac ccaaaccatt gttattgacc accatagaag ggatcaggat
    48061 tttccagata atgcggtcat tacttatatc gaaagtggtg caagtagtgc cagtgagttg
    48121 gtaacggaat tgattcagtt ccagaattct aagaaaaatc gtttgagtcg tatgcaagca
    48181 agtgttttga tggctggtat gatgttggat actaaaaatt tcacctcgcg agtaactagt
    48241 cggacatttg atgttgctag ctatctcaga acgcgcggaa gtgatagtat tgctatccag
    48301 gaaatcgctg cgacagattt tgaagaatat cgtgaggtca atgaacttat tttacagggg
    48361 cgtaaattag gttcagatgt actaatagca gaggctaagg acacgaaatg ctatgataca
    48421 gttgttatta gtaaggcagc agatgccatg ttagccatgt caggtattga agcgagtttt
    48481 gttcttgcga agaatataca aggatttatc tctatctcag ctcgaagtcg tagtaaactg
    48541 aatgtacaac ggattatgga agagttaggc ggtggaggcc actttaattt ggcagcagct
    48601 caaattaaag atgtaacctt gtcagaagca ggtgaaaaac tgacagaaat tgtattaaat
    48661 gaaataaagg aaaaggagaa agaagaatga aagtaatctt tttagcagat gttaaaggaa
    48721 aaggtaaaaa aggcgaaatt aaggaagtac caacagggta tgcgcaaaac tttcttatca
    48781 aaaagaatct agccaaagaa gcgactgctc aagctgtagg tgaacttcgt ggtaaacaaa
    48841 aatcggaaga aaaagctcac gctgagatga ttgcagaagg aaaagcaatt aaagcacaac
    48901 ttgaagcaga agaaactgtt gtagaatttg ttgaaaaagt tggtccagat ggtcgtacct
    48961 ttggttctat taccaataag aagattgcag aagaattgca aaagcaattt ggaattaaga
    49021 ttgataaacg tcatattcaa gtacaagctc cgattcgagc ggttggtttg attgatgtgc
    49081 cagtgaaaat ctatcaagat atcacaagtg taatcaatct tcgtgtgaaa gaaggataag
    49141 tttacacttt cttgacaaga ttgtaaaagg aagggaagtc tgatggcaga agtagaagag
    49201 ttacgagtac aacctcaaga tatcttagct gagcaatccg ttttaggggc tatctttatt
    49261 gatgagagta aacttgtttt tgtgcgagaa tacattgagt ctcgggactt ttttaagtat
    49321 gcccatcgtt tgattttcca agccatggtc gatttatccg atcgtggtga tgccatagat
    49381 gcaacaacgg ttcgtactat ccttgataat caaggtgatt tacagaatat tggtggcttg
    49441 tcttacttgg ttgagattgt taattctgtg ccaacttctg ctaatgcgga gtattatgct
    49501 aagattgttg cagaaaaagc aatgctacgt cgtttaattg ccaagttgac agagtctgtc
    49561 aaccaagctt acgaagcgtc acaaccagct gatgaaatta ttgctcaggc agaaaaaggg
    49621 ttgattgatg tcagtgaaaa tgcaaatcga agcgggttta agaacattcg agatgtgttg
    49681 aatctcaact ttggaaatct ggaagctcgc tcgcaacaaa cgaccgatat tacaggtatt
    49741 gcgacaggtt atcgtgattt ggatcatatg acaacaggac ttcatgagga ggagttgatt
    49801 atcttagcag ctcgtccagc agttggtaag acagcatttg ccttgaatat cgctcagaac
    49861 attgggacta agttggacaa aacggttgct attttttcac tcgaaatggg tgcggaaagc
    49921 ttggtagatc gtatgttagc tgcagaaggc ttggtggagt cacattctat ccgtacaggg
    49981 caattgacag atgaggagtg gcaaaaatat actattgctc agggtaatct agctaacgcc
    50041 agtatctata tcgatgatac gccaggtatt cggattacag agattcgttc tcgttctcgt
    50101 aaattggctc aagaaactgg aaatcttggt ttgattttga tagactattt gcaacttatc
    50161 acgggaactg gtcgagaaaa tcgtcaacaa gaagtttctg aaatttctcg tcagttgaaa
    50221 atactagcca aggaattgaa ggttccagta atcgctctga gtcagctttc tcgtggtgta
    50281 gaacaacgtc aggacaagag accggtcttg tctgatattc gtgaatctgg gtctattgag
    50341 caggacgctg atatcgtagc ttttctctat cgcgatgact actatgaacg tggtggtgaa
    50401 gaagaggagg gtatcccaaa taataaggtg gaagttatta tcgagaaaaa ccgtagtgga
    50461 gctcgtggaa cagtggaatt gattttccaa aaagaataca ataaattttc aagtatctca
    50521 aagagggagg cataagatgt cagatgcatt tacagatgta gccaagatga aaaaaatcaa
    50581 agaagaaatc aaggcacatg agggacaagt cgtagaaatg actttggaga atggtcgtaa
    50641 gcgccaaaaa aatagattgg gtaagctaat tgaagtttat ccatccctat ttattgtgga
    50701 gtttggggat gtggaaggag ataaacaagt taatgtttac gttgaatcct ttacttactc
    50761 agatattctt acagaaaaga atttgattca ttatcttgac taaagtgaga aattttctca
    50821 ctttttcttt tttctccgaa taatttaggt gaaggcaatc atcgctttat attatttttc
    50881 aaggaggaag aatgaaaatt ttaccgttta tagcaagagg aacaagttat tacttgaaga
    50941 tgtcagttaa aaagcttgtt ccttttttag tagtaggatt gatgctagca gctggtgata
    51001 gtgtctatgc ctattccaga ggaaatggat cgattgcgcg tggggatgat tatcctgctt
    51061 attataaaaa tgggagccag gagattgatc agtggcgcat gtattctcgt cagtgtactt
    51121 cttttgtagc ctttcgtttg agtaatgtca atggttttga aattccggca gcttatggaa
    51181 atgcgaatga atggggacat cgtgctcgtc gggaaggtta tcgtgtagat aatacaccga
    51241 cgattggttc cattacttgg tctactgcag gaacttatgg tcatgttgcc tgggtgtcaa
    51301 atgtaatggg agatcagatt gagattgagg aatataacta tggttataca gaatcctata
    51361 ataaacgagt tataaaagca aacacgatga caggatttat tcattttaaa gatttggatg
    51421 gtggcagtgt tgggaatagt caatcctcaa cttcaacagg cggaactcat tattttaaga
    51481 ccaagtctgc tattaaaact gaacctctag ctagcggaac tgtgattgat tactattatc
    51541 ctggggagaa ggttcattat gatcagatac ttgaaaaaga cggctataag tggttgagtt
    51601 atactgccta taatggaagc tatcgttatg ttcaattgga ggctgtgaat aaaaatcctc
    51661 taggtaattc tgttctttct tcaacaggtg gaactcatta ttttaagacc aagtctgcta
    51721 tcaaaactga acccctagtt agtgcaactg tgattgatta ctattatcct ggagagaagg
    51781 ttcattatga tcaaattctc gaaaaagacg gctacaagtg gttgagttat acggcttata
    51841 acggaagtcg tcgctatata cagctagagg gagtgacttc ttcacaaaat tatcagaatc
    51901 aatcaggaaa tatctctagc tatggatcca ataatagttc aactgtcggt tggaagaaaa
    51961 taaatggtag ttggtatcat ttcaaatcaa atggttctaa atcaacagga tggctgaaag
    52021 acggttctag ctggtattat ttgaaattat ctggtgaaat gcagacagga tggttaaagg
    52081 agaatggctc gtggtattat ctgggtagtt caggggcaat gaaaacaggc tggtaccagg
    52141 tctctggtaa gtggtattat tcttactctt caggcgcctt agctgttaat acgacggtgg
    52201 atggctacag agtaaacagt gatggagaac gagtatagaa aattggagta ggagaaattt
    52261 cctgctcttt tctgtaagca gtttccttga catttttctt attttgcgct atcatatata
    52321 catataatat atgggagtct gtgtacagtc tgagaggaag tgttaaactt cgaccgcacc
    52381 tgatctggat aatgccagcg gagggaacga tacttagtct aattttgcac cttttccatg
    52441 tatggtaaag gtttttcttt tttttaaaag gaaaacgaga agaggaggtt cttatgaaag
    52501 caagcattgc cttgcaagtt ttacccctag cacaggggat tgatcggata gctgttattg
    52561 atcaggtcat tgcttatctg caaactcaag aagtgacgat ggtagtgaca ccatttgaaa
    52621 cggtcttgga aggggagttt gatgagctta tgcgcattct aaaagaagcg ctggaagtgg
    52681 cagggcagga ggcagacaat gtctttgcca atgtcaaaat aaatgtagga gagattttaa
    52741 gtattgatga gaaacttgaa aagtatactg agacgacaca ttagtctatt gggctttctc
    52801 ggagtattgt caatctggca gttagcaggt tttcttaaac ttctccccaa gtttatcctg
    52861 ccgacacctc ttgaaattct ccagcccttt gttcgtgaca gagaatttct ctggcaccat
    52921 agctgggcga ccttgagagt ggctttactg gggctgattt tgggagtttt gattgcctgt
    52981 cttatggctg tgctcatgga tagtttgact tggctcaatg acctgattta ccctatgatg
    53041 gtggtcattc agaccattcc gaccattgcc atagctccta tcctggtctt gtggctaggt
    53101 tatgggattt tgcccaagat tgtcttgatt atcttaacaa caacctttcc catcatcgtt
    53161 agtattttgg acggttttag gcattgtgac aaggatatgc tgactttgtt tagtctgatg
    53221 cgagcaaacc cttggcaaat cctgtggcat tttaaaatcc cggttagcct gccttacttt
    53281 tatgcaggtc tgagggtcag tgtctcctac gcctttatca caactgtggt atctgagtgg
    53341 ttgggaggtt ttgaaggtct tggtgtttat atgattcagt ctaaaaaact gtttcagtat
    53401 gataccatgt ttgccattat tattctggtg tcgattatca gtcttttggg tatgaagctg
    53461 gtcgatatca gtgaaaaata tgtgattaaa tggaaacgta cttaaaatag agcgtttttg
    53521 aaaaagaaaa gaggaaatca aaatgaagaa aacatggaaa gtgtttttaa cgcttgtaac
    53581 agctcttgta gctgttgtgc ttgtggcctg tggtcaagga actgcttcta aagacaacaa
    53641 agaggcagaa cttaagaagg ttgactttat cctagactgg acaccaaata ccaaccacac
    53701 agggctttat gttgccaagg aaaaaggtta tttcaaagaa gctggagtgg atgttgattt
    53761 gaaattgcca ccagaagaaa gttcttctga cttggttatc aacggaaagg caccatttgc
    53821 agtgtatttc caagactaca tggctaagaa attggaaaaa ggagcaggaa tcactgccgt
    53881 tgcagctatt gttgaacaca atacatcagg aatcatctct cgtaaatctg ataatgtaag
    53941 cagtccaaaa gacttggttg gtaagaaata tgggacatgg aatgacccaa ctgaacttgc
    54001 tatgttgaaa accttggtag aatctcaagg tggagacttt gagaaggttg aaaaagtacc
    54061 aaataacgac tcaaactcaa tcacaccgat tgccaatggc gtctttgata ctgcttggat
    54121 ttactacggt tgggatggta tccttgctaa atctcaaggt gtagatgcta acttcatgta
    54181 cttgaaagac tatgtcaagg agtttgacta ctattcacca gttatcatcg caaacaacga
    54241 ctatctgaaa gataacaaag aagaagctcg caaagtcatc caagccatca aaaaaggcta
    54301 ccaatatgcc atggaacatc cagaagaagc tgcagatatt ctcatcaaga atgcacctga
    54361 actcaaggaa aaacgtgact ttgtcatcga atctcaaaaa tacttgtcaa aagaatacgc
    54421 aagcgacaag gaaaaatggg gtcaatttga cgcagctcgc tggaatgctt tctacaaatg
    54481 ggataaagaa aatggtatcc ttaaagaaga cttgacagac aaaggcttca ccaacgaatt
    54541 tgtgaaataa tgacagaaat tagactagag cacgtcagtt atgcctatgg tcaggagagg
    54601 attttagagg atatcaacct acaggtgact tcaggcgaag tggtttccat cctaggccca
    54661 agtggtgttg gaaagaccac cctctttaat ctaatcgctg ggattttaga agttcagtca
    54721 gggagaattg tccttgatgg tgaagaaaat cccaaggggc gcgtgagtta tatgttgcaa
    54781 aaggatctgc tcttggagca caagacggtg cttggaaata tcattctgcc cctcttgatt
    54841 caaaaggtgg ataaggcaga agctatttcc cgagcggata aaattcttgc gaccttccag
    54901 ctgacagctg taagagacaa gtatcctcat gaacttagcg gtgggatgcg ccagcgtgta
    54961 gccttactcc ggacctacct ttttgggcac aagctctttc tcttagatga ggcctttagc
    55021 gccttggatg agatgacaaa gatggaactc cacgcttggt atcttgagat tcacaagcag
    55081 ttgcagctaa caaccctgat catcacgcat agtattgagg aggccctcaa tctcagcgac
    55141 cgcatctata tcttgaaaaa tcgccctggg cagattgttt cagaaattaa actagattgg
    55201 tctgaagatg aggacaagga agtccaaaag attgcctaca aacgtcaaat tttggcggaa
    55261 ttaggcttag ataagtagaa aaatagggag ttggtgaaga ttatccttta ccagcgccct
    55321 ttttctttta aaaatgagaa aatttcggta taatagtcaa acaaggtcaa ggtttaaaga
    55381 gagaggtggg tttgttatga gatttaaaaa tacatcggat catattgagg cctacatcaa
    55441 ggcgatttta gatcaatctg gtatcgtgga gttgcaacgg agtcagttgg cagatacctt
    55501 tcaggttgtt cctagtcaga ttaactacgt gatcaagaca cgctttacgg aaagtagagg
    55561 ctacttggtt gaaagtaagc gtggtggcgg aggctacatt cgtataggac ggattgagtt
    55621 ttctagtcat catgaaatgc tccgggagct gctttactcg attggtgagc gagtcagtca
    55681 agaaatttat gaggatattc tccagctttt ggttgagcag gaattgatga ccaagcagga
    55741 gatgaatttg ctagaatcag tagctttgga tcgcgtttta ggagaagaag ctccagttgt
    55801 tcgagcaaac atgctacgtc agatcataca agaggtagat agaaaaggga agtaagatga
    55861 actattcaaa agcattgaat gaatgtatcg aaagtgccta catggttgct ggacattttg
    55921 gagctcgtta tctagagtct tggcacttgt tgattgccat gtctaatcac agttatagtg
    55981 tagcaggggc aactttaaat gattatccgt atgagatgga ccgtttagaa gaggtggctt
    56041 tggaactgac tgaaacggac tatagccagg atgaaacctt tacggaattg ccgttctccc
    56101 gtcgtttgca ggttcttttt gacgaagcag agtatgtagc gtcagtggtc catgctaagg
    56161 tgctagggac agagcacgtc ttctatgcga ttttgcatga tggcaatgcc ttggcaactc
    56221 gtatcttgga gagggctggt ttttcttatg aagacaagaa agatcaggtc aagattgctg
    56281 cccttcgtcg aaatttagaa gaacgggcag gctggactcg tgaagacctc aaggctttac
    56341 gccaacgcca tcgtacagta gctgacaagc aaaattctat ggccaatatg atgggcatgc
    56401 cgcagactcc tagtggtggt cttgaggact atacgcatga tttgacagag caagcgcgtt
    56461 ctggcaagtt agaaccagtc atcggtcggg acaaggaaat ctcacgtatg attcaaatct
    56521 tgagccgtaa gactaagaac aaccctgtct tggttgggga tgctggtgtc gggaaaacag
    56581 ctctggccct tggtcttgcc cagcgtattg ctagtggtga cgtgcctgcg gaaatggcta
    56641 agatgcgcgt gttagaactt gatttgatga atgtcgttgc agggacacgc ttccgtggtg
    56701 actttgaaga acgcatgaat aatatcatca aggatattga agaagatggc caagtcatcc
    56761 tctttatcga tgaactccac accatcatgg gttctggtag cgggattgat tcgactctgg
    56821 atgcggccaa tatcttgaaa ccagccttgg cgcgtggaac tttgagaacg gttggtgcca
    56881 ccactcagga agaatatcaa aaacatatcg aaaaagatgc ggctctttct cgtcgtttcg
    56941 ctaaagtgac gattgaagaa ccaagtgtgg cagatagtat gactatttta caaggtttga
    57001 aggcgactta tgagaaacat caccgtgtac aaatcacaga tgaagcggtt gaaacagcgg
    57061 ttaagatggc tcatcgttat ttaaccagtc gtcacttgcc agactctgct atcgacctct
    57121 tggacgaagc agcagcaaca gtgcaaaata aggcaaagca tgtaaaagca gacgattcag
    57181 atttgagtcc agctgacaag gccctgatgg atggcaagtg gaaacaggca gcccagctaa
    57241 tcgcaaaaga agaggaagta cctgtctaca aagacttggt gacagagtct gatattttga
    57301 ccaccttgag tcgcttgtca ggaatcccag ttcaaaaact gactcaaacg gatgctaaga
    57361 agtatttaaa tcttgaagca gaactccata aacgtgtcat cggtcaagat caagctgttt
    57421 caagcattag ccgtgccatt cgccgtaatc agtcaggaat tcgcagtcac aagcgtccga
    57481 tcggttcctt tatgttccta ggacccacag gtgtcggtaa gaccgagttg gccaaggctt
    57541 tggcagaagt tctctttgat gacgaatcag cccttatccg ctttgatatg agtgagtata
    57601 tggagaaatt cgcagccagc cgtctaaatg gagctcctcc aggctatgtg ggttacgaag
    57661 aaggtgggga gttgacagag aaggttcgca ataaacccta ttccgttctc ctctttgatg
    57721 aggtagagaa ggcccaccca gatatcttta atgttctctt gcaggttctg gatgacggtg
    57781 tcttgacaga tagcaaggga cgcaaggtcg atttttcaaa taccattatc attatgacat
    57841 cgaacctagg tgcgactgcc cttcgtgatg ataagactgt tggttttggg gctaaggata
    57901 ttcgttttga ccaggaaaat atggaaaaac gcatgtttga agaactgaaa aaagcttata
    57961 gaccggaatt catcaaccgt attgatgaga aggtggtctt ccatagccta tctagtgacc
    58021 atatgcagga agtggtgaag attatggtca agcctttagt ggcaagtttg gctgaaaaag
    58081 gcattgactt gaaattacaa gcttcagctc tgaaattgtt agcaaatcaa ggatatgacc
    58141 cagagatggg agctcgccca cttcgcagaa ccctgcaaac agaagtggag gacaagttgg
    58201 cagaacttct tcttaaggga gatttagtgg caggcagcac acttaagatt ggtgtcaaag
    58261 caggccagtt aaaatttgat attgcataaa agaataaaag tatcagcatc tgaccataag
    58321 tcacagtgga gtgaaactca atgaaaatca aagaacaaac taggcagcta gccgcaggtt
    58381 gctcaaaaca ctgtttttag attgtagata gagctgacgt ggtttgaaga gattttcgaa
    58441 gagtataagc tgcaagatga atgattttct tgtattgacg ttgttgttga caaaaagtag
    58501 cggataaatg aaatccattc cattatcata gatgataggc tggtaggaaa ttttcaaata
    58561 gcatatagga aatagatgta tggagttctg gtagtagaaa gggagagaga tgaacatttt
    58621 agttgcagat gacgaggaaa tgattagaga aggaattgca gcatttctga cagaagaggg
    58681 ttatcatgtc attatggcta aggatggaca agaggtcttg gaaaaatttc aagatctccc
    58741 tatccatctc atggtactgg atttaatgat gcctaggaag agtggttttg aagtgttaaa
    58801 agaaatcaat caaaagcacg atattcctgt catcgtcttg agtgctctgg gagatgaaac
    58861 tactcagtca caggtatttg atctctatgc tgatgatcat gtgacaaaac ctttttcttt
    58921 ggtactgctt gtcaagcgta ttaaggcgct tatcagacgt tactacgtca tagaggatct
    58981 ttggcgatat caggatgtaa cagtggattt tacctcttac aaagcacatt ataaaaatga
    59041 agaaattgat ctcaaaccaa aggaattact ggtactaaag tgtttgattc agcataaaaa
    59101 tcaagtttta agtagagagc agatattgga agaaatttca aaagatgtag ctgatttacc
    59161 ttgtgatagg gtcgttgatg tctatattcg tactcttcgc aaaaaattag ctttagattg
    59221 tatcgtgact gtgaaaaatg ttgggtataa gattagctta tgataaaaaa tcctaaatta
    59281 ttaaccaagt cttttttaag aagttttgca attctaggtg gtgttggtct agtcattcat
    59341 atagctattt atttgacctt tcctttttat tatattcaac tggagggggg aaagtttaat
    59401 gagagcgcaa gagtgtttac ggagtattta aagactaaga catctgatga aattccaagc
    59461 ttactccagt cttattcaaa gtccttgacc atatctgctc accttaaaag agatattgta
    59521 gataagcggc tccctcttgt gcatgacttg gatattaaag atggaaagct atcaaattat
    59581 atcgtgatgt tagatatgtc tgttagtaca gcagatggta aacaggtaac cgtgcaattt
    59641 gttcacgggg tagatgtcta caaagaagca aagaatattt tgcttttgta tctcccatat
    59701 acatttttgg ttacaattgc tttttccttt gttttttctt atttttatac taaacgcttg
    59761 ctcaatcctc ttttttacat ttcagaagtg actagtaaaa tgcaagattt ggatgacaat
    59821 attcgttttg atgaaagtag gaaagatgaa gttggtgaag ttggtgaagt tggaaaacag
    59881 attaatggta tgtatgagca cttgttgaag gttattcatg agttggaaag tcgtaatgag
    59941 caaattgtaa aattgcaaaa tcaaaaggtt tcctttgtcc gcggagcatc acatgagttg
    60001 aaaacccctt tagccagtct tagaattatc ctagagaata tgcagcataa tattggagat
    60061 tacaaagatc atccaaaata tattgcaaag agtataaata agattgacca gatgagccac
    60121 ttattggaag aagtactgga gtcttctaaa ttccaagagt ggacagagtg tcgtgagacc
    60181 ttgactgtta agccagtttt agtagatatt ttatcacgtt atcaagaatt agctcattca
    60241 ataggtgtta caattgaaaa tcaattgaca gatgctacca gggtcgtcat gagtcttagg
    60301 gcattggata aggttttgac aaacctgatt agtaatgcaa ttaaatattc agataaaaat
    60361 gggcgcgtaa tcatatccga gcaagatggc tatctctcta tcaaaaatac atgtgcgcct
    60421 ctaagtgacc aagaactaga acatttattt gatatattct atcattctca aatcgtgaca
    60481 gataaggatg aaagttccgg tttgggtctt tacattgtga ataatatttt agaaagctat
    60541 caaatggatt atagttttct cccttatgaa cacggtatgg aatttaagat tagcttgtag
    60601 acagattagt tttttattaa agttcatata gggttaacat aagtgtgtta ttctttgtat
    60661 agataaaaga aaggatacta atatggtatt agcgattatt ttagtaacat tctttattcg
    60721 attgattttt ttaaagcgtt cgatagagaa tgagaaacga atccttagca atggcgggaa
    60781 agaatttgga gttgagaata caaaacgatt aactatggct catattgttt tttatctctc
    60841 ttgcttggtt gaggcaatgg tgcacaagac aatttttgat ggcatgggca tggttggttt
    60901 agtcttgctt attttttcta tgctgatgtt gatgttggtg attcacttgt tgggagatat
    60961 ttggacagtg aagcttatgc ttgtcaataa tcacaaatat gtagatcata tcttgtttag
    61021 gacagtaaaa catcctaatt actttttaaa tattcttcct gagttgattg gcttgacctt
    61081 gttgagtcat gcttatgtga cttttgtttt agtttttcca gtttatgcag ttattttgta
    61141 tcgacgaata gctgaagagg aaaagctatt acatgaagtt ataatcccaa atggaagcat
    61201 aaagagataa atacaaaatt cgatttatat acagttcata ttgaagtaat atagtaatag
    61261 acttcatgcg aaacaaaata tggtacaata gttctatgaa ttatgaagca aggttgagaa
    61321 tatttttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa
    61381 acgcttcgga ttacgaatga atttgattgc tggcattatc aatcatgaac taggattcta
    61441 gttttgcagg aagtctaatg ttaagaaaaa tattggagaa aataaacatg tttgcatcaa
    61501 aaagcgaaag aaaagtacat tattcaattc gtaaatttag tattggagta gctagtgtag
    61561 tagttgctag cttgttctta ggaggagtag ttcatgcaga agaggttggt ggtaggaata
    61621 cccccacggt tacatctagt gggcaagata tatcgaagaa gtatgctgat gaagtcaagt
    61681 cgcatctaga agaaatgttg agtgggatcc aattagatag aagaaaacat acccaaaatt
    61741 tcaactttaa cctaaagttg agcaaaattc aaacgaagta tttgcgtgaa ttaagtgttt
    61801 taaagtcgaa atctgagttg acgttagaaa caaaagaaga gttgctgtca aaaaccaaag
    61861 cagagttaga cgcagctttt gagcagttta aaaaagatac attgaaacta ggagaaaagg
    61921 tagcagaagc tgagaagaag gttgaagaag ctaagaaaaa agccaaggct caaaaagaag
    61981 aagatcaccg taactaccca accaatactt acaaaacgct tgaacttgaa attgctgagt
    62041 ccgatgtgaa agttaaagaa gcggagcttg aactattgaa agaggaagct caaactcgaa
    62101 acgaggacac aattaaccaa gcaaaagcga aagttaagag tgaacaagct gaggctacaa
    62161 ggttaaaaaa aatcaagaca gatcgtgaag aagctgaggc tacaaggtta aaaaaaatca
    62221 agacagatcg tgaagaagca gaagaagaag ttaaagataa accaaagaag cggacaaaac
    62281 gaggagctct tggagagcca gcaacacctg ataaaaaaga aaatgatgcg aagtcttcag
    62341 attctagcgt aggtgaagaa actcttccaa gcccatccct gaaaccagga aaaaaggtag
    62401 cagaagctga gaagaaggtt gcagaagctg agaaaaaagc caaggctcaa aaagaagaag
    62461 atcgccgtaa ctacccaacc aatacttaca aaacgcttga acttgaaatt gctgagtccg
    62521 atgtggaagt taaaaaagcg gagcttgaac tagtaaaaga ggaagctaag aaacctttaa
    62581 acgagggcac aattaagcaa gcaaaagcgg aagttgagag taaaaaagct gaggctacaa
    62641 ggttagaaaa aatcaagaca gatcgtaaaa aagcagaaga agaagctaaa cgaagagcag
    62701 cagaagaaga taaagttaaa gaaaaaccag ctgaacaacc acaaccagcg ccggcccctc
    62761 aaccagaaaa accaactgaa gagcctgaga atccagttcc agctccaaaa ccagagaagc
    62821 cagctgaaca accaaaagca gaaaaaacag atgatcaaca agctgaagaa gactatgctc
    62881 gtagatcaga agaagaatat aatcgcttga ctcaacagca accgcaaaaa ccagagcaac
    62941 cagctcctgc accaaaaata ggctggaaac aagaaaacgg tatgtggtac ttctacaata
    63001 ctgatggttc aatggcgaca ggatggctcc aatacaatgg ttcatggtac tacctaaaca
    63061 gcaatggcgc tatggcaaca ggttggctcc aaaacaacgg ttcatggtac tatctaaacg
    63121 ctaatgg
//
LOCUS       DAVKZI010000007        59679 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKZI010000007 DAVKZI010000000
VERSION     DAVKZI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.007"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            14..490
                     /locus_tag="VXB18_000525"
     CDS             14..490
                     /locus_tag="VXB18_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0381777.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            528..833
                     /locus_tag="VXB18_000526"
     CDS             528..833
                     /locus_tag="VXB18_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0381778.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            881..2356
                     /locus_tag="VXB18_000527"
     CDS             881..2356
                     /locus_tag="VXB18_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0381779.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2379..2456
                     /locus_tag="VXB18_000528"
                     /pseudo
     CDS             2379..2456
                     /locus_tag="VXB18_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2661..9359
                     /locus_tag="VXB18_000529"
     CDS             2661..9359
                     /locus_tag="VXB18_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0381780.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGIYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESDKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTNLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQLIHTTLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVVVRKGMLELHKPGAVTLNAEYEGATGQITLTIQVNTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKASAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDFVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAGLALLGLSAGLVVTKGKKED"
     gene            complement(9607..10464)
                     /locus_tag="VXB18_000530"
                     /pseudo
     CDS             complement(9607..10464)
                     /locus_tag="VXB18_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10674..11033)
                     /locus_tag="VXB18_000531"
     CDS             complement(10674..11033)
                     /locus_tag="VXB18_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0381781.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            11125..12081
                     /locus_tag="VXB18_000532"
                     /pseudo
     CDS             11125..12081
                     /locus_tag="VXB18_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            12065..12622
                     /locus_tag="VXB18_000533"
     CDS             12065..12622
                     /locus_tag="VXB18_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0381782.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12615..12869
                     /locus_tag="VXB18_000534"
     CDS             12615..12869
                     /locus_tag="VXB18_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381783.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12881..14935
                     /locus_tag="VXB18_000535"
     CDS             12881..14935
                     /locus_tag="VXB18_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0381784.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYSRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            15114..15974
                     /locus_tag="VXB18_000536"
     CDS             15114..15974
                     /locus_tag="VXB18_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0381785.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQILFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            16185..16895
                     /gene="ccdA2"
                     /locus_tag="VXB18_000537"
     CDS             16185..16895
                     /gene="ccdA2"
                     /locus_tag="VXB18_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0381786.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKELYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16915..17481
                     /locus_tag="VXB18_000538"
     CDS             16915..17481
                     /locus_tag="VXB18_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0381787.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17492..18604
                     /gene="msrB"
                     /locus_tag="VXB18_000539"
     CDS             17492..18604
                     /gene="msrB"
                     /locus_tag="VXB18_000539"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0381788.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18827..19564
                     /locus_tag="VXB18_000540"
     CDS             18827..19564
                     /locus_tag="VXB18_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0381789.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            19561..21252
                     /locus_tag="VXB18_000541"
     CDS             19561..21252
                     /locus_tag="VXB18_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0381790.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VTFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            21368..21931
                     /locus_tag="VXB18_000542"
     CDS             21368..21931
                     /locus_tag="VXB18_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0381791.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILSSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            21953..27862
                     /locus_tag="VXB18_000543"
     CDS             21953..27862
                     /locus_tag="VXB18_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0381792.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKTEESPKEEPKSEIK
                     PTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEESKVEPP
                     VEQAKGPEQPVQPTQAEQPRIPKDSSQPEDPKEDRGAEETPKQEDTPKQEDTQPEVVE
                     TKDEAANQPVEEPKVETPAVEKQTEPKVEQVGEPVEPSEDEKAPVSPEKQPEAPEEKA
                     VEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNDLGPVLETAKGV
                     YASEPVKQPEVNSETNKLKTAIDALNVDKSELQEQLRVAEQKQQADYSAKTWREFKIA
                     ELQAKEINNQTTPLPKQSEIDAATKALQDALQALAVDKTVLQNAINTANSKREEEYTA
                     QTWKALEDALTAVNPVNEDETATQSKVDEATRNLEEAINNLVLLTEKPVLTFIETDKK
                     ALEREVVAKYSLENQNKTKIKSITATLKKGETVVSTVELIGDDVTNETITSAFKNLEY
                     YKEYTLSTTMVYDRGDGDVTEILDNQPIQLDLKKVELKNIKRTDLIKYENGKETNESL
                     ITTVPDDKRNYYLKITSKNQKTTLLAVKNIEETTVNGTPVYKVTAIADNLVSRTADNK
                     FEEEYVHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYIT
                     KEFTGKLLSSEGKQFAITELEHPLFNVITNATINNVNFENVEIERSGQDNIASLANTM
                     KGSSVITNVKITGTLSGRNNVAGFVNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAG
                     TNYRGIVRKAYVDATITGNKTRASLLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVS
                     NPVEVGAIASKTWPVGTVSNSVSYAKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGY
                     SSGNRSFRKSKTFTKLTKEQADAKVTTFNITADKLESDLSPLAKLNEEKAYSSIQDYN
                     AEYNQAYKNLEKLIPFYNKDYIVYQGNKLNKEHHLNTKEVLSVTAMNNNEFITNLDEA
                     NKIIVHYADGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSI
                     LESVELQSQTMYQHLNRLGDYRVNAIKDLYLEESFTDVKKNLTNLITKLVQNEEHQLN
                     DSPAARQMIRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVL
                     DRLIEIGSKENNIKGSRTFDAFGQVLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFID
                     ATEDHVYIAERASEVEEIKNSKHRAFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAI
                     AFGSAERLGKKSLEDIKDIVNKAADGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGY
                     NAPGGWVEKYGRYNTDKVYTPLREFFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYV
                     HLEMVGEYGISVYTHETTHVNDRAIYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEF
                     GSLGINMVFKRKNDGNQWYITDPKTLKTREDINRYMKGYNDTLTLLDEIEAESVISQQ
                     NKDLNSAWFKKIDREYRDNNKLNQWDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNP
                     GNGIYKPEAISYNDQSPYVGVRMMTGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENG
                     FLGYASNKYKQQSKTDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLT
                     TFEVNGSSVSSYDDLLTLFKEAVKKDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQ
                     QTDSFKTSIFK"
     gene            27923..29644
                     /gene="pabB"
                     /locus_tag="VXB18_000544"
     CDS             27923..29644
                     /gene="pabB"
                     /locus_tag="VXB18_000544"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0381793.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSSIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            29764..31290
                     /locus_tag="VXB18_000545"
     CDS             29764..31290
                     /locus_tag="VXB18_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0381794.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            31377..32296
                     /locus_tag="VXB18_000546"
                     /pseudo
     CDS             31377..32296
                     /locus_tag="VXB18_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            32431..33390
                     /locus_tag="VXB18_000547"
     CDS             32431..33390
                     /locus_tag="VXB18_000547"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0381795.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            33487..34326
                     /locus_tag="VXB18_000548"
     CDS             33487..34326
                     /locus_tag="VXB18_000548"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0381796.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(34374..34544)
                     /locus_tag="VXB18_000549"
     CDS             complement(34374..34544)
                     /locus_tag="VXB18_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0381797.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            34665..35549
                     /gene="miaA"
                     /locus_tag="VXB18_000550"
     CDS             34665..35549
                     /gene="miaA"
                     /locus_tag="VXB18_000550"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0381798.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            35542..36780
                     /gene="hflX"
                     /locus_tag="VXB18_000551"
     CDS             35542..36780
                     /gene="hflX"
                     /locus_tag="VXB18_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0381799.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQFKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            36773..37396
                     /locus_tag="VXB18_000552"
     CDS             36773..37396
                     /locus_tag="VXB18_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0381800.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            37411..38340
                     /locus_tag="VXB18_000553"
     CDS             37411..38340
                     /locus_tag="VXB18_000553"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0381801.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            38361..39116
                     /locus_tag="VXB18_000554"
     CDS             38361..39116
                     /locus_tag="VXB18_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0381802.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(39170..40078)
                     /locus_tag="VXB18_000555"
     CDS             complement(39170..40078)
                     /locus_tag="VXB18_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0381803.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            40142..40411
                     /locus_tag="VXB18_000556"
     CDS             40142..40411
                     /locus_tag="VXB18_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0381804.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            40411..40791
                     /locus_tag="VXB18_000557"
     CDS             40411..40791
                     /locus_tag="VXB18_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0381805.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            40880..41050
                     /locus_tag="VXB18_000558"
     CDS             40880..41050
                     /locus_tag="VXB18_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381806.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNI"
     gene            complement(41147..41872)
                     /locus_tag="VXB18_000559"
     CDS             complement(41147..41872)
                     /locus_tag="VXB18_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0381807.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            42034..43875
                     /gene="typA"
                     /locus_tag="VXB18_000560"
     CDS             42034..43875
                     /gene="typA"
                     /locus_tag="VXB18_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0381808.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            43895..44149
                     /locus_tag="VXB18_000561"
     CDS             43895..44149
                     /locus_tag="VXB18_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0381809.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            44512..44811
                     /locus_tag="VXB18_000562"
     CDS             44512..44811
                     /locus_tag="VXB18_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0381810.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSVVSKWDSHSDKGSAPAGKTSEAWIWTKFGEQVSFYYDYD"
     gene            44882..46903
                     /locus_tag="VXB18_000563"
     CDS             44882..46903
                     /locus_tag="VXB18_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0381811.1"
                     /translation="MKKLFILLSTFFLSFFFAWIIVLRAPQYLYASYDSVTLLRVKKE
                     AQEPTREVFEQELEKFVNSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKQFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKAIADRKTPPYSLAFRMLLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWHDRVDYYQISFGL
                     GDRVNDTENQNKWYEFSKEAVEKEQALFVKENLIHFANPQGKNENGETLDTYSPDANV
                     LYVSPSYLDKENVAVNDETRQKLAHLQKGEFGLLLPESLRSQEAELKKVFEERLNYYG
                     KSSEDKDAPLEYEMRAIVSYLPTGQKRFVYNNGESPVSIQYLTDPILVVFTPTSTGDS
                     FISKYVWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILSSRDLVIGLLTLFVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            46905..47546
                     /locus_tag="VXB18_000564"
     CDS             46905..47546
                     /locus_tag="VXB18_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381812.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKSSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            47650..49002
                     /locus_tag="VXB18_000565"
     CDS             47650..49002
                     /locus_tag="VXB18_000565"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0381813.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDIPGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            49006..50064
                     /locus_tag="VXB18_000566"
     CDS             49006..50064
                     /locus_tag="VXB18_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0381814.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            50074..51294
                     /gene="divIB"
                     /locus_tag="VXB18_000567"
     CDS             50074..51294
                     /gene="divIB"
                     /locus_tag="VXB18_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0381815.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTNQRSSRR"
     gene            51527..52228
                     /gene="pyrF"
                     /locus_tag="VXB18_000568"
     CDS             51527..52228
                     /gene="pyrF"
                     /locus_tag="VXB18_000568"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0381816.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSVMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            52262..52894
                     /locus_tag="VXB18_000569"
     CDS             52262..52894
                     /locus_tag="VXB18_000569"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0381817.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            53074..53477
                     /locus_tag="VXB18_000570"
                     /pseudo
     CDS             53074..53477
                     /locus_tag="VXB18_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            53573..54337
                     /locus_tag="VXB18_000571"
     CDS             53573..54337
                     /locus_tag="VXB18_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381818.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            54337..55089
                     /locus_tag="VXB18_000572"
     CDS             54337..55089
                     /locus_tag="VXB18_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381819.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTAILFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLALLSIIIPLTVFSVHRNWRRV"
     gene            55099..55797
                     /locus_tag="VXB18_000573"
     CDS             55099..55797
                     /locus_tag="VXB18_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381820.1"
                     /translation="MGKLSSHIWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            55794..56441
                     /locus_tag="VXB18_000574"
     CDS             55794..56441
                     /locus_tag="VXB18_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381821.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(56521..57386)
                     /locus_tag="VXB18_000575"
                     /pseudo
     CDS             complement(56521..57386)
                     /locus_tag="VXB18_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(57398..58162)
                     /locus_tag="VXB18_000576"
                     /pseudo
     CDS             complement(57398..58162)
                     /locus_tag="VXB18_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(58163..58450)
                     /locus_tag="VXB18_000577"
     CDS             complement(58163..58450)
                     /locus_tag="VXB18_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0381822.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(58460..58840)
                     /locus_tag="VXB18_000578"
     CDS             complement(58460..58840)
                     /locus_tag="VXB18_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0381823.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(58800..59480)
                     /locus_tag="VXB18_000579"
     CDS             complement(58800..59480)
                     /locus_tag="VXB18_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0381824.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
BASE COUNT        18468 a        10803 c        12939 g        17469 t
ORIGIN      
        1 aagggaaaaa cttatggtat tagattattt ctttgacaaa aaccttgtgt tttgcttaga
       61 agcggataat caagaacatc tctttgatca ggttgcaact ttattggaag aacgagaaat
      121 tgtaactcca acttatcgtg aagccttgat cacgcgtgaa aagtcatttc caactggttt
      181 agatatggaa tttctaggaa aggacttgcc aaatgtagcg attcctcaca cagatattgt
      241 tcataatcta gctgagaaag tggtggttgt tcgattagaa aaaccagtaa cttttcacaa
      301 tatgatagct cctgataagg aagtagaagt atctctactc ttctttatca ttaacaattc
      361 aagttcaagt caaacgaaca ttctggctca gttgatggac tttttcacag gaaatggtca
      421 tcttgaagac ctatcaaaaa tttctgaacc agaaaaactt tatgcttaca ttgctgaagc
      481 aaccgcttaa tcttgtctat taaaaaataa aatcggagga aatccaaatg attaaaattc
      541 ttgctgcctg cggtgcaggt gttaactcaa gtcaccaaat taaaagtgct ctagaagaag
      601 aactttcaaa ccgtggttat gatgttcact gtgatgcagt catggtgaaa gatgtaaacg
      661 aagaccttat gaaaggttac gatatcttta caccaatcgc tgcaacagac cttggttttg
      721 aaccaggtat cccagttatc gaagctgggc caatcttatt ccgtatccca gcaatgagcg
      781 ctccagtatt tgacaatatt gaagcagcta ttaaagaaca tggattaagc taattctaat
      841 ttgttaacat tcatataaca taaaaaaggg aggaactgtt atggatgcaa tctttgacct
      901 aatcggaaag gttttcaatc ccatcttaga aatgggtgga cctgtcatca tgttgatcat
      961 tttgacagta ttggctttac tttttggagt gaaattctcc aaagcgcttg aaggtggtat
     1021 caaacttgcc atcgctctta caggtatcgg tgctatcatc ggtatgctaa atggtgcttt
     1081 ctcagcatca cttgcaaaat tcgttgaaaa cactggtatc caattgagta ttacagacgt
     1141 tggttgggca ccactcgcaa caatcacttg gggttctgct tggacactat acttcttgct
     1201 catcatgttg attgtcaacg tagtgatgct tgctatgaag aaaaccgata cacttgatgt
     1261 cgatatcttt gatatctggc acttgtctat cacaggtctc ttgattaaat ggtatgctga
     1321 taacaatggt gtgagtcaag gggtttcact ctttattgct acagcagcta tcgtccttgt
     1381 cggtgtgttg aaaattatca actctgactt gatgaaacct acatttgatg accttcttaa
     1441 cgccccaagt tcatcaccaa tgacatcaac tcacatgaac tacatgatga acccagttat
     1501 catggttttg gataagattt ttgaaaaatt cttcccaggc cttgataaat atgactttga
     1561 tgctgctaaa ttgaacaaga aaatcggttt ctggggatct aaattcttca tcggtttcat
     1621 ccttggtatc gttatcggta ttatgggaac tccacatcca attgcaggtg ttgcagatgc
     1681 agataaatgg cgtcttgtta tcaaaggatg gttgtctctt ggtttgactg ccggtgtatc
     1741 tttggaactc ttctcactta tcggttcatg gttcatcgca gccgtagaac cactatcaca
     1801 aggtattaca aacgttgcta ctaaacgtct tcaaggacgt aaattcaata tcggtcttga
     1861 ctggccattc atcgctggtc gtgctgaaat ctgggcttgt gccaacgtac ttgcaccaat
     1921 catgttgatt gaagcagtgc ttctttcaaa agttggaaat ggtatcttgc cacttgcagg
     1981 tatcatcgct atgggtgtta ctccagctct cttggttgta actcgtggta aattgctccg
     2041 tatgattatc ttcggaacac tcttgttgcc actcttcctt ctttcaggta cccttattgc
     2101 accatttgca acagaacttg ctaaaggtgt aggtgccttc ccagaaggtg tgagccaaac
     2161 tcaattgatt actcactcta ctcttgaagg accaatcgaa aaacttcttg gttggacaat
     2221 tggtaacact acaactggtg atatcaaagc aatccttggt gcagtagtct tccttgtatt
     2281 ctatatcggt atctttgctt ggtacagaaa acaaatgatc aaacgtaacg aagagtacgc
     2341 agcaaaagca aaataatgcg ctcctataaa atataaactc aatgaaaatc aaagagcaaa
     2401 ctaggaaact agccacaggt tgctcaaaac acagttttga ggttgtagat aagactggcg
     2461 aagtcagctc aaaacatggt tttgaggtta tagatgaaac tgacgaagtc agtaatcata
     2521 catacggcaa ggcgacactg acgaagtttg aattggattt tcgcagagtg taaattgttg
     2581 aaactaggtt gtcataccat gtataccact tgggctttgg tagtagctaa ctgcactaaa
     2641 tataatataa ggagggtttt atggggaaag gccattggaa tcggaaaaga gtttatagca
     2701 ttcgtaagtt tgctgtggga gcttgctcag taatgattgg gacttgtgca gttctattag
     2761 gaggaaatat agctggagaa tctgtagttt atgcggatga aacacttatt actcatactg
     2821 ctgagaaacc taaagaggaa aaaatgatag tagaagaaaa ggctgataaa gctttggaaa
     2881 ctaaaaatgt agttgaaagg acagaacaaa gtgaacctag ttcaactgag gctattgcat
     2941 ctgagaagaa agaagatgaa gccgtaactc caaaagagga aaaagtgtct gctaaaccgg
     3001 aagaaaaagc tccaaggata gaatcacaag cttcaaatca agaaaaaccg ctcaaggaag
     3061 atgctaaagc tgtaacaaat gaagaagtga atcaaatgat tgaagacagg aaagtggatt
     3121 ttaatcaaaa ttggtatttt aaactcaatg caaattctaa ggaagccatt aaacctgatg
     3181 cagacgtatc tacgtggaaa aaattagatt taccgtatga ctggagtatc tttaacgatt
     3241 tcgatcatga atctcctgca caaaatgaag gtggacagct caacggtggg gaagcttggt
     3301 atcgcaagac tttcaaacta gatgaaaaag acctcaagaa aaatgttcgc cttacttttg
     3361 atggcgtcta catggattct caagtttatg tcaatggtca gttagtgggg cattatccaa
     3421 atggttataa ccagttctca tacgatatca ccaaatacct tcacaaagat ggtcgtgaga
     3481 atgtgattgc tgtccatgca gtcaacaaac agccaagtag ccgttggtat tcaggaagtg
     3541 gtatctatcg tgatgtgact ttacaagtga cagataaggt gcatgttgag aaaaatggga
     3601 caactatttt aacaccaaaa cttgaagaac aacaacatgg caaggttgaa actcatgtga
     3661 ccagcaaaat cgtcaatacg gacgacaaag accatgaact tgtagccgaa tatcaaatcg
     3721 ttgaacgagg tggtcatgct gtaacaggct tagttcgtac agcgagtcgt accttaaaag
     3781 cacatgaatc aacaagccta gatgcgattt tagaagttga aagaccaaaa ctctggaccg
     3841 ttttaaatga caaacctgcc ttgtacgaat tgattacgcg tgtttaccgt gacggtcaat
     3901 tggttgatgc taagaaggat ttgtttggtt accgttacta tcactggact ccaaatgaag
     3961 gtttctcttt gaatggtgaa cgtattaaat tccatggagt atccttgcac cacgaccatg
     4021 gggcgcttgg agcagaagaa aattataaag cagaatatcg ccgtctcaaa caaatgaagg
     4081 agatgggagt taactccatc cgtacaaccc acaaccctgc tagtgagcaa accttgcaaa
     4141 tcgcagcaga actaggttta ctcgttcagg aagaggcttt tgatacttgg tatggtggca
     4201 agaaacctta tgactatgga cgtttttttg aaaaagatgc cactcaccca gaagctcgaa
     4261 aaggtgaaaa atggtctgat tttgacctac gtaccatggt cgaaagaggc aaaaacaacc
     4321 ctgctatctt catgtggtca attggtaatg aaataggtga agctaatggt gatgcccact
     4381 ctttagcaac tgttaaacgt ttggtcaagg ttatcaagga tgttgataag actcgctatg
     4441 ttaccatggg agcagataaa ttccgtttcg gtaatggtag cggagggcat gagaaaattg
     4501 ctgatgaact cgatgctgtt ggatttaact attctgaaga taattacaaa gcccttagag
     4561 ctaagcatcc aaaatggttg atttatggat cagaaacatc ttcagctacc cgtacacgtg
     4621 gaatttacta tcgccctgaa cgtgaattga aacatagcaa tggacctgag cgtaattatg
     4681 aacagtctga ctatgggaat gatcgtgttg gttgggggaa aacagcaacc gcttcatgga
     4741 cttttgaccg tgacaacgct ggctatgctg gacagtttat ctggacaggt acggactata
     4801 ttggtgaacc tacaccatgg cataaccaaa atcaaactcc tgttaagagc tcttactttg
     4861 gtatcgtaga tacagccggc attccaaaac atgacttcta cctctaccaa agccaatggg
     4921 tttctgttaa aaagaaaccg atggtacacc ttcttcctca ctggaactgg gaaaacaaag
     4981 aattagcatc caaagtagct gactcagaag gtaagattcc agttcgtgct tattcgaatg
     5041 cttctagtgt agaattattc ttgaatggaa aatctcttgg tcttaagact ttcaataaaa
     5101 aacaaaccag cgatgggcgg acttaccaag aaggtgcaaa tgctaatgaa ctttatcttg
     5161 aatggaaagt tgcctatcaa ccgggtacct tggaagcaat tgctcgtgat gaatctgaca
     5221 aggaaattgc tcgagataag attacgactg ctggtaagcc agcggcagtt cgtcttatta
     5281 aggaagacca tgcgattgca gcagatggaa aagacttgac ttacatctac tatgaaattg
     5341 ttgacagcca ggggaatgtg gttccaactg ctaataatct ggttcgcttc caattgcatg
     5401 gccaaggtca actggtcggt gtagataacg gagaacaagc cagccgtgaa cgctataagg
     5461 cgcaagcaga tggttcttgg attcgtaaag catttaatgg taaaggtgtt gccattgtca
     5521 aatcaactga acaagcaggg aaattcaccc ttactgccca ctctgatctc ttgaaatcga
     5581 accaagtcac tgtctttact ggtaagaaag aaggacaaga aaagactgtt ttggggacag
     5641 aggtgccaaa agtacagacc attattggag aggcacctga aatgcctacc actgttccgt
     5701 ttgtatacag tgatggtagt cgtgcagaac gtcctgtaac ctggtcttta gtagatgtga
     5761 gcaagcctgg tattgtaacg gtgaaaggta tggctgacgg acgagaagta gaagctcgtg
     5821 tagaagtgat tgctcttaaa tcagagctac cagttgtgaa acgtattgct ccaaatacta
     5881 acttgaattc tgtagacaaa tctgtttcct atgttttgac tgatggaagt gtacaagagt
     5941 atgaagtgga caagtgggag attgccgaag aagataaagc taagttagca attccaggtt
     6001 ctcgtattca agcgaccggt tatttagaag gtcaactaat tcatacaacc cttgtggtag
     6061 aagaaggcaa tcctgcagca cctgtagtgc caactgttac tgttggaggt gaagcagtaa
     6121 caggtcttac tagtcgacaa ccaatgcaat atcgtactct atcttatggt gcccaattgc
     6181 cagaagtcac agcaagtgct gaaaatgctg atgtgacagt tcttcaagca agcgcagcaa
     6241 acggcatgcg tgcaagcata tttgttcagc ctaaagatgg tggccctctt caaacctatg
     6301 caattcaatt cctagaagaa gcaccaaaaa ttgctcactt gagcttgcaa gtggaaaaag
     6361 ctgacagtct caaagaagac caaactgtca aattgtcggt tcgagctcac tatcaagatg
     6421 gaacgcaagc tgtattacca gctgataaag taaccttctc tacaagtggt gaaggggaag
     6481 ttgtagtccg aaaaggaatg cttgagttgc ataaaccagg agcagtcact ctgaacgctg
     6541 aatatgaggg tgctacaggt caaatcactc tcactatcca agtcaatact gagaagaaga
     6601 ttgcgcaatc catccgtcct gtaaatgtag tgacagattt gcatcaggaa ccaagtcttc
     6661 cagcaacagt aacagttgag tatgacaaag gtttccctaa aactcataaa gtcacttggc
     6721 aagctattcc gaaagaaaaa ctagactcct atcaaacatt tgaagtacta ggtaaagttg
     6781 aaggaattga ccttgaagcg cgtgcaaaag tctctgtaga aggtatcgtt tcagttgaag
     6841 aagtcagtgt gacaactcca atcgcagaag caccacaatt accagaaagt gttcggacat
     6901 atgattcaaa tggtcacgtt tcatcagcta aggttgcatg ggatgcgatt cgtccagagc
     6961 aatacgctaa ggaaggtgtc tttacagtta atggtcgctt agaaggtacg caattaacaa
     7021 ctaaacttca tgttcgcgta tctgctcaaa ctgagcaagg tgcaaacatt tctgaccaat
     7081 ggaccggttc agaattgcca cttgcctttg cttcagactc aaatccaagc gacccagttt
     7141 caaatgttaa tgacaagctc atttcctaca ataaccaacc agccaatcgt tggacaaact
     7201 ggaatcgtag taatccagaa gcttcagtcg gtgtcctatt cggagattca ggtattttga
     7261 gcaaacgctc cgttgataat ctaagtgtcg gattccacga agaccatgga gttggtgcac
     7321 cgaagtctta tgtgattgag tattatgttg gtaagactgt cccaacagct cctaaaaacc
     7381 ctagttttgt tggtaatgag gaccatgtct ttaatgattc tgccaactgg aaaccagtta
     7441 ctaatctaaa agcctctgct caactcaagg ctggagaaat gaaccacttt agctttgata
     7501 aagttgaaac ctatgctgtt cgtattcgca tggtgagagc agacaacaaa ctaggaacgt
     7561 ctatcacaga ggtacaaatc tttgcgaaac aagttgcggc agccaagcaa ggacaaacaa
     7621 gaatccaagt tgacggtaaa gacttagcaa acttcaaccc tgatttgaca gactactacc
     7681 ttgagtctgt agatggaaaa gttacggcag tcacagcaag tgttagcaac aatggcctcg
     7741 ctaccgtcgt tccaagcgtt cgtgaaggtg agccggttcg tgtcatcgcg aaagctgaaa
     7801 atggcgacat cttaggagaa taccgtctgc acttcactaa ggataagaac ttactttctc
     7861 ataaaccagt tgctgcggtt aaacaagctc gcttgctaca agtaggtcaa gcacttgaat
     7921 tgccgactaa ggttccagtt tacttcacag gtaaagacgg ctacgaaaca aaagatttgt
     7981 cagttgaatg ggaagaagtt ccagcagaaa atctgacaaa agcaggtcaa tttaccgttc
     8041 gaggccatgt ccttggtagt gattttgttg ctgaggtcac tgtacgagtg acagacaaac
     8101 taggcgaagc tctttcagat aaccctaact atgatgaaaa cagtaaccag gcctttgctt
     8161 cagcaaccaa tgatattgac aaaaactctc atgaccgcgt tgactatctc aatgacggag
     8221 atcattcaga aaatcgtcgt tggacaaact ggtctccaac accatcttct aatccagaag
     8281 tatcagcggg tgtgatcttc cgtgaaaatg gtaagattgt agaacggact gttgctcaag
     8341 ccaaacttca cttctttgca gatagtggta cggatgcacc aactaaactc gttttagaac
     8401 gctatgtcgg tccagagttt gaagtgccaa cctactattc aaactaccaa gcctacgacg
     8461 cagaccatcc attcaacaat ccagaaaatt gggaagctgt gccttatcgt gcggataaag
     8521 acatcgcagc tggtgatgaa atcaacgtaa catttaaagc tgtcaaagcc aaagctatga
     8581 gatggcgtat ggagcgtaaa gctgacaaga gcggtgttgc gatgattgag atgaccttcc
     8641 ttgcaccgag tgaattgcct caagaaagta cgcaatcgaa gattcttgta gatggaaaag
     8701 aacttgctga tttcgctgaa aatcgtcaag actatcaaat tacctataaa ggtcaacggc
     8761 caaaagtctc agttgaagaa aacaatcaag tagcttcaac tgtggtagat agtggagaag
     8821 atagccttcc agtacttgtt cgcctcgttt cagaaagtgg aaaacaagtc aaggaatacc
     8881 gtatccactt gactaaggaa aaaccagttt ctgagaagac agttgctgct gtacaagaag
     8941 atcttccaaa actcgaattt gttgaaaaag atttggcata caagacagtt gagaaaaaag
     9001 attcaacact gtatctaggt gaaactcgtg tagaacaaga aggaaaaact ggtaaagaac
     9061 gtatctttac agcgattaat cctgatggaa gtaaggaaga aaaactccgt gaagtggtag
     9121 aagctccgac agaccgcatc gtcttggttg gaaccaaacc agtagctcaa gaagctaaaa
     9181 aaccacaagt gtcagaaaaa gcagatacaa aaccaattga ttcaagtgaa gctagtcaaa
     9241 ctaataaagc ccagttacca aatacaggta gtgcggcaag ccaagcagca gtagcaggtt
     9301 tagctcttct aggtttgagt gcaggattag tagttactaa aggtaaaaaa gaagactaga
     9361 aattttgata ccttctttat cattaaagac caaagaaaaa ctcttgtcct aaatagaaga
     9421 taaagagtct gggacaaaat agttctcaac cacaaaaaag ctagatattt ccaattgcgg
     9481 aactctagct ttttaatttt gagtcgttct cttattgtat agtagattga aactagagta
     9541 gtacacttct acttctaaaa cattgttaga aatcgatttg actgtcctta tcgatttgtc
     9601 ctgttcttat ttcatttcat tatgttttag gaggttattg gccataagta ccaatcccat
     9661 gtcaattctc acttgacgct tgcctctcag attacatctc ttgtaaccca aacaagcctt
     9721 taactgccca aagacaggtt ccacatcaat cttgcgttga gcgaaaatct gtctaccttg
     9781 gggagataaa agcgcctgac attctttagc tttcaagttt tgatagcgtt cgttcatata
     9841 tagccccctt ttgaggggct gattcaggtt cgtcggcata gtaaaccttg atttcctgtt
     9901 gaaagtctgt ctgtgttttc tgatgtttgg tatggtgaaa acgataatac cagccatcag
     9961 gatgtgtgta gctatcctcc ttgtcattat agtgccaatt cgctaagttt ttagctgact
    10021 gtttataccc tctcttttgt tccttatcaa acatggcata tttaatcaga aggggagtga
    10081 tttcttcttg aaaatagact tgtatctgtt cttgaagttt ggcggagaat ttctctgtcg
    10141 ttttcttcca cacaaaacta tacttgttgg cattggattc aatcttagtt ccgtcaataa
    10201 acaaacaatc taaggtcact aactcttcca tttttcaatt tttcgaccag agaaaatccc
    10261 ttgtgaatag acaaatagaa gagtagatac aagcatttta gggtgataag acgggcgatc
    10321 aaaggcatga tagaaggcgt agaagtgatg ttcctccaag gtattcacca ctttttcaat
    10381 agtaaagacg agatggtctt gtggtaagaa ggaactgatt tctagtggta aagttgtttg
    10441 atttgtgtta tagtgaatat gcatgggata gcctttctaa atggtttatt aagcaattct
    10501 attttaccaa gactatcgta accatgcaaa aaagcaacgg caaatccgtt gcctttttgg
    10561 atataagaga ctattgtccc atactctttt ctttgtataa aattgtatag tgttattgtc
    10621 tatactattt tgtagagaaa gcaaaaatcc ctagaaaatg cttagggatt cgactatttc
    10681 attaagaaca attcaacaat catttctata tacatgataa gggttaataa gaatcctgca
    10741 cgccagaaga atttgatgaa tttaggatag taaaagctgc gttttttcaa aaggaagaaa
    10801 aagacgagaa taatggctag gatcgagagg gctagcccca gtctagggag gaaattatgg
    10861 gtaaaggttt tagctgtaat caagtaatac tcaaatacca agactggaaa agccaaatcc
    10921 gcaaagtttc gtcctagttt ttttaatcta aaaagtttgg ttaggataat gcagatgact
    10981 aaggtcagta tcaataataa aatagatgct aatttcatta aaatcatacc catattgtat
    11041 cataaaaaaa ggctaatgga aacgagaaac agaggaattt ataggaaagt caggcttttg
    11101 agattgtggg tgatttttgt tataatgaaa gttataaaat cttataatac cttgaatgat
    11161 tattatcgaa aactctttgg agaaaagact tttaaagtcc ctattgatgc gggatttgac
    11221 tgtcccaatc gtgatggaac tgtggctcat ggaggctgta ctttttgtac ggtttcaggt
    11281 tctggagata ctattgtagc cccagatgcg cctatccgtg agcaatttta taaggaaatt
    11341 gactttatgc accgtaagtg gccggatgtt cagaagtatc tggtttattt tcaaaatttt
    11401 accaacaccc atgaaaaggt ggaagttatt cgagagcgtt atgaacaggc tatcaatgag
    11461 ccaggtgtgg taggaatcaa tattggaatg cgcccagact gtttaccaga cgaaaccatc
    11521 gaatatttgg ctgagttatc ggagtgcatg catgtgacgg ttgaattggg cttgtagact
    11581 acttatgaag caacttctga cctgattaac cgtgcgtatt cttatgaatt gtaggtggaa
    11641 acggtcaagc gtttgagaaa gtatcccaag attgagattg tttcccattt gattaatggt
    11701 ttgcctggtg aaacccatga gatgatggtt gaaaatgtcc gccgttgtgt cacgaataac
    11761 gatattcaag ggattaaact gcatttgctc catcttatga caaatactcg tatgcaacga
    11821 gattaccatg agggacgttt acaattgatg agtcaggacg aatatgtcag ggtcatctgt
    11881 gaccaactgg aaatcattcc caaacatatc gtcatccatc gaatcacagg agatacacct
    11941 agggatatgc tgattgggct tatgtggagc ctcaataaat gggaagctct caacagcatt
    12001 aagatggaga tgcgacgtcg tggaagtgtt caaggatgta aggctgtaaa acaggagttt
    12061 gaaaatgaaa agaccacttg agatggcaca tgattttttg gctgaggtcg tgacaaaaga
    12121 ggatgtcgta gtggatgcga ctatgggaaa tggtcatgac acgctttttt tagccaagct
    12181 agccaagcaa gtctatgcct ttgatattca gaagcaagcc ttggaaaaga cccaagagcg
    12241 tttgcatcag gctggcttga caaatgccca gttaatcttg caaggccatg agacactgga
    12301 ccagtttgtg acaaaagcta aggcagggat ttttaatctg ggctatttgc cgtcagctga
    12361 taagtctgtc atcacccgac cgcagacaac gattgaggca ttagaaaagc tatgtggctt
    12421 acttgtcaaa ggtggacgaa ttgctattat gatttactat ggtcatgaag gaggcgacct
    12481 cgagagagat gctgtcttgg attttgtgat ccagttgaac caacaagagt acacagctgc
    12541 catttaccga actttaaacc aagtcaacaa cccgccgttt ttagtgatga ttgaaaaatt
    12601 agagagatac agacatggat aaacaatacc tacacgaaaa gctggatgcc atgcgccaga
    12661 attttgttga atcaactcac cacgaacgag cggtgggcgt gctagaccaa gcgcatatga
    12721 gcaaaaaaat gcttaaaatc aagaaaaaat tagttgctct tgaaatggaa cggtgccaga
    12781 gaaaaattga gcacaaagac tgttccaaga ttgaccaaaa aatcaaagag cagaaggaga
    12841 tatttgaatc ctgttgtaaa aaagattaag gaggacgtgc gtggaattac tgatttacct
    12901 catcctattt ttactggttt tgattgtctc aagtacaacc aataagctcc tacccttttt
    12961 gcctctccct ttggtgcaga ttcttttggg aattgtgatt ggtctctttt tacctaatac
    13021 tgactttcac cttaatacgg agttgttttt ggcactggtt atcggcccct tgcttttccg
    13081 agaggctgaa gaagcagatg ttacggctat tttaaaacac tggcgaatca ttgtttatct
    13141 catatttcca gtgattttta tctcgaccct gagtttgggt ggcttggccc atcttctttg
    13201 gttcagcctt cccttggcag cttgcttggc tgttggggca gcccttggtc ctacggactt
    13261 ggtggccttt gcctctcttt cggagcgttt tagctttcct aagcgcgtgt ccaatattct
    13321 taagggcgaa ggactcttga atgatgcttc tggtttggtg gcttttcagg tagctttgac
    13381 agcttggaca actggagctt tttctctggg gcaagctagc agttcgctca tcttttcaat
    13441 cctaggcggt tttttaattg gatttttaac agccatgacc aaccgcttcc tccatacctt
    13501 cttgctaagt gtgcgcgcaa cggatattgc cagtgaactt ttattagaat tgagtttgcc
    13561 tctagtgacc ttctttctgg cagaagaagt ccatgtttca gggattattg ccgtcgtagt
    13621 tgctggaatt ttaaaggcaa gtcgcttcaa gaaaatcacg ctcctcgaag cccaagtgga
    13681 tacggtgacc gagacggtct ggcatacagt gacctttatg ctcaacggtt ctgtctttgt
    13741 gattttaggg atggagttgg aaatgatagc agaacctatc ttgaccaatc caatctataa
    13801 tcctctactt ttattgctat ctctcatcgc ccttaccttt gtcctctttg tcattcgttt
    13861 tattatgatc tatggctatt atgcctatag aacccgacgc ctcaagaaaa agctaaataa
    13921 gtatatgaag gacatgtttc tcttgacctt ttcaggtgtt aagggaacgg tgtcgattgc
    13981 tacgattctc ttgataccaa gtaatctaga acaggagtat cctctcttgc ttttccttgt
    14041 tgcaggtgtg acgcttgtca gctttttaac aggtctcttg gtcttgcctc atctttctga
    14101 tgaagaggaa gaaagcaagg attatctcat gcatatcgcc attttgaatg aagtaacgct
    14161 agagttggaa aaagagttgg aagacaccag aaataaactt cccctctatg cggctattga
    14221 caattatcat ggacgtattg aaaatctcat tttaagccaa gaaaaccagg atgatcaaga
    14281 agattgggct gctttgaaac tcttgattct tagtattgaa agtgatggtt tggaacaggc
    14341 ctatgaagag gggaacatta gcaatcgtgc ttaccgagtt taccaacgtt atctgaaaaa
    14401 tatagaacaa ggaatcaatc gtaaacttgc ctcaagactg acctattatt tccttgtttc
    14461 tttgcggatt ttacgttttc tccttcatga agtttttact ctcggaaaga ccttccgtag
    14521 ctggaagaac aaggagcaaa gccgtctccg tgctcttgat tatgaccaaa ttgcagagct
    14581 ctatcttgcc aatacggaga tgattattga aagtttggaa aacctgaagg gagtctacag
    14641 ccgctctttg attagtttta tgcaggagtc tcgtcttcga gaaacaacta ttattagcag
    14701 tggtgccttt gtcgaacggg ttatcaatcg tgtcaaaccc aacaatatca atgaaatgct
    14761 gagaggctat tatctggagc gcaagttgat tttcgaatac gaagaaaaac gattgattac
    14821 gactaagtat gccaagaaat tacgacaaaa tgtaaataac ttagagaact attccttgaa
    14881 ggaagctgcc aataccctgc cgtatgatat ggtggaattg gtaagaagaa attagttaat
    14941 attcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtatgta tgtgactgac
    15001 ttcgtcagtc ttatctacaa cctcaaaaca gtgttttgag cagcttgcgg ctagctttct
    15061 agtttgctct ttgattttca ttgagtataa gattataaat gaaggagtat gacatgaaaa
    15121 agtggtggaa agagctgata gacaagcctt tattaaaagc ttttttgcat tattatcaag
    15181 catcagatag tgagttgacc agtgtcgcag tagcctacta ttggttgatt tcgattttcc
    15241 ccctgctttt ggtggtggtc aatatcctcc cctattttca gattcctgtg ggagaatttt
    15301 tgggctttat gaaagacgtt ctgcccccaa gcctctatga aggtgtggaa aaaatagcca
    15361 gagaagtttt gacgcaacct tcaacaggtt tattgagttt ttctgtttta tcggcgttat
    15421 ggagtttttc aaaatctatg aatttcttgc aaaaagcttt taacaaggct tatggcgtcg
    15481 aaaagagtcg tggacttatt tcccatcaga tgctaagtct cctagtcagt tttggcttgc
    15541 agatcctctt tgcgtttgcc ttgtttttga tcttatttgg tcagatgatt ttggctttac
    15601 ttgctcatta ttggacaaaa gatggcatta tctatcaggc tttacaaggg ttggcaggtc
    15661 ctctgattta cgccctcctc tttgctatct tggtcatgct ttattatttt cttcccaatc
    15721 tatctaacag gaaaattagc tataccctac caggcagtgc ctttgttctc ttagtgattt
    15781 taggtttact aactctgttc tctagttatc tcaattacta tgtccatcat ttggtggatg
    15841 tccgaatttt aggttccgtt cttcttgttg ttatgatgtt ttggtttatc ttgattgcta
    15901 aaattgttat cctaggcgcg gttatcaatg ccagtatgca gagtttgaaa gatccggtct
    15961 ttaaaaaaga ctaactattt atccattaca aaagcgcata gtatcaagac tttatagaac
    16021 cttgatacta tgcgcttttg tgctttgaca gttttttgta tagtttttgt ccaagatttc
    16081 taaatcatct gattaaattc ctattttccc ctatcattgt ccctgttttt tcgaaaatgg
    16141 aaggagtata ataaatctat caataaaatg ataggaggaa ctttatgggt catattttct
    16201 tttttctaag tgtctttttg gcagggattc tatccttctt ttctccttgt atcttacctt
    16261 tgttaccggt ctatacagga gtgttactag atgataagga tggtgctcag gcttctagcg
    16321 gcaaattttc aatctcagtt actagtttat tacgaactct ggcctttata gcaggaattt
    16381 cctttatatt tattttgttg ggctatggag ctggtttttt aggcgatttg ctttatgctt
    16441 cttggttcca atatcttact ggggcaatta ttatccttct tggtttgcac caaatggaga
    16501 ttctacactt taaggagctt tataaggaaa agaggctaca actgcaagga caggggcaaa
    16561 atggtaaggg ctatagtcag gcatttttat tgggcttgac ctttagtttt gcttggacgc
    16621 cttgcgtggg gccggttctg gggtctgttt tggccttggc ggcttcaggt ggttcaggag
    16681 cttggcaggg agctggtctc atgttggtgt atacgctggg cttggcgcta ccattcttgc
    16741 ttctagctct gacctctagt tatgttttga aacatttccg aaaacttcat ccctatctcg
    16801 gaatcctcaa aaaagtgggt ggttttctca ttattgtgat gggactcttg gttctgtttg
    16861 gaaatgcttc aattttaagt caattatttg aataaaatgg aaaggaatat caatatgaaa
    16921 aaatggcaaa catgtgttct tggagcaggt tcgctccttt gtttgacggc ttgttcaggc
    16981 aagtccgtga ctagtgaaca ccaaacgaaa gatgaaatga agacggagca gacagctagt
    17041 aaaacaagcg cagctaaagg gaaagaggtg gctgattttg aattgatggg agtagatggc
    17101 aagacctacc gtttatctga ttacaagggc aagaaagtct atctcaaatt ctgggcttct
    17161 tggtgttcca tctgtctggc tagtcttcca gatacggatg agattgctaa agaagctggt
    17221 gatgactatg tggtcttgac agtagtgtca ccaggacata agggagagca atctgaagcg
    17281 gactttaaga attggtataa gggattggat tataaaaatc tcccagtcct agttgaccca
    17341 tcaggcaaac ttttggaaac ttatggtgtc cgttcttacc caacccaagc ctttatagac
    17401 aaagaaggca agctggtcaa aacacatcca ggattcatgg aaaaagatgc aattttgcaa
    17461 actttgaagg aattagccta ggaggtgtct tatgaatgat aagttaaaaa tcttcttgtt
    17521 gctaggagta ttttttctag ccataaccgg tttctatgtt ctattgatac gaaatgcagg
    17581 gcagacagat gcctcgcaaa ttgaaaaggc ggcagttagc caaggaggaa aagcagtgaa
    17641 aaaaacagaa attagtaaag acgcagactt gcacgaaatt tatctagctg gaggttgttt
    17701 ctggggagtg gaggaatatt tctcacgcgt tcccggggtg acggatgccg tttcaggcta
    17761 tgcaaatggt agaggagaaa caaccaagta cgaattgatt aaccaaacag gtcatgcaga
    17821 aaccgtccat gtcacctatg atgccaagca aatttctctc aaggaaatcc tgcttcacta
    17881 tttccgcatt atcaatccaa ccagcaaaaa taaacaagga aatgatgtgg ggacccagta
    17941 ccgtactggt gtttattaca cagatgacaa ggatttggaa gtgattaacc aagtctttga
    18001 tgaggtggct aagaaatacg atcaacctct agcagttgaa aaggaaaact tgaagaattt
    18061 tgtggtggct gaggattacc atcaagacta tctcaagaaa aatccaaatg gctactgcca
    18121 tatcaatgtt aatcaggcgg cctatcctgt cattgatgcc agcaaatatc caaaaccaag
    18181 tgatgaggaa ttgaaaaaga ccctgtcacc tgaggagtat gcagttaccc aggaaaatca
    18241 aacagaacga gctttctcaa accgttactg ggataaattt gaatccggta tctatgtgga
    18301 tatagcaact ggggaacctc tcttttcatc aaaagacaaa tttgagtctg gttgtggctg
    18361 gcctagtttt acccaaccca tcagtccaga tgttgtcacc tacaaggaag ataagtccta
    18421 caatatgacg cgtatggaag tgcggagccg agtaggagat tctcaccttg ggcatgtctt
    18481 tacggatggt ccacaggaca agggcggctt acgttactgt atcaatagcc tctctatccg
    18541 ctttattccc aaagaccaaa tggaagaaaa aggctacgct tatttactag attatgttga
    18601 ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtagggtt
    18661 actgacttcg tcagttttat ctacaacctc aaagcggtac tttgagaaac ctgtggctat
    18721 cttcctagtt tactttttga tttttattga gtataagagg tctttcctaa gcagttagag
    18781 gagaattttg ctatactgat actagtaagt ggtaaaggag cagatcatga cctacacaat
    18841 cttaatcgta gaagatgaat atctggtaag acaaggtttg actaaactgg tcaatgtagc
    18901 agcctacgat atggaaatca ttggtcaggc tgaaaatgga aggcaggctt gggaattgat
    18961 ccaaaagcag gtgccagata tcattttaac cgatatcaac atgcctcatc taaatggcat
    19021 ccagttggcc agtctggtac gagaaaccta tcctcaggtt catttggtct ttttaacagg
    19081 ttacgatgat tttgattatg ccttgtctgc tgtcaaacta ggtgtggacg actacctgct
    19141 caaacccttt tctcgtcagg atattgagga aatgttgggg aaaatcaaac aaaaactaga
    19201 caaggaagag aaagaagagc agttacaaga tttattgact aataggtttg aaggaaacat
    19261 ggcccagaaa atccagtctc atctggctga tagccaattt agtttaaagt ctttagccag
    19321 tgacttaggt tttagtccga cctatctgag ttccttgatt aagaaagagt tgggcttgcc
    19381 ttttcaggat tatctggtga gagaacgtgt taaacaagcc aagctcttgc ttttaactac
    19441 agatctgaag atttatgaga tcgcagagaa ggttggtttt gaagatatga actattttac
    19501 ccaacgtttt aagcagattg caggtgtgac acctcgtcag tttaagaagg gagaagaccg
    19561 atgaagcgtt cttctctttt agttagaatg gttatttcca tctttctggt ctttctcatt
    19621 ctcctagctc tggttggaac tttctactat caatcaagtt cttcagccat tgaggccacc
    19681 attgagggca acagccaaac gaccatcagc cagactagcc actttattca gtcttatatc
    19741 aaaaaactag aaaccacttc gaccggtttg acccagcaga cggatgttct ggcctatgct
    19801 gagaatccca gtcaagacaa ggtcgaggga atccgagatt tgtttttgac catcttgaag
    19861 tcagataagg acttgaaaac tgttgtgctg gtgaccaaat ctggtcaggt catttctaca
    19921 gatgacagtg tgcagatgaa aacttcctct gatatgatgg ctgaggattg gtaccaaaag
    19981 gccattcatc agggagctat gcctgttttg actccagctc gtaaatcaga tagtcagtgg
    20041 gtcatttctg tcactcaaga acttgttgat gcaaagggag ccaatcttgg tgtgcttcgt
    20101 ttggatattt cttatgaaac tctggaagcc tatctcaatc aactccagtt ggggcagcag
    20161 ggctttgcct tcattatcaa tgaaaaccat gaatttgtct accatcctca acacacagtt
    20221 tatagttcgt ctagcaaaat ggaggctatg aaaccctaca tcgatacagg tcagggttat
    20281 actcctggtc acaaatccta cgtcagtcaa gagaagattg caggaactga ttggacggta
    20341 cttggcgtgt catcattgga aaagttagac caggttcgga gtcagctctt gtggaccttg
    20401 cttggggcca gtgtcacatc tcttcttgtc tgtctctgct tagtgtggtt cagtcttaaa
    20461 cgctggattg ctcctttgaa ggatttgaga gaaaccatgt tggaaattgc ttctggtgct
    20521 caaaatcttc gtgccaagga agttggtgcc tatgaactga gagaagtaac tcgccaattt
    20581 aatgccatgt tggatcagat tgatcagttg atggtagcta ttcgtagcca ggaagaaacg
    20641 acccgtcagt accaacttca agccctttcg agccagatta atccacattt cctctataac
    20701 actttggaca ccatcatctg gatggctgaa tttcatgata gtcagcgagt ggtgcaggtg
    20761 accaagtcct tggcaaccta tttccgcttg gcgctcaatc aaggcaagga cttgatttgt
    20821 ctctctgacg aaatcaatca tgtccgccag tatctcttta tccagaaaca acgctatgga
    20881 gataagctgg aatacgaaat taatgaaaat gttacctttg ataatttagt cttacccaag
    20941 ctggtcctac aaccccttgt agaaaatgct ctttaccatg gcattaagga aaaggaaggt
    21001 cagggccata ttaaactttc tgtccagaaa caggattcgg gattggtcat ccgtattgag
    21061 gatgatggcg ttggcttcca agatgctggt gatagtagtc aaagtcaact caaacgtggg
    21121 ggagttggtc ttcaaaatgt cgatcaacgg ctcaaacttc attttggagc caattaccag
    21181 atgaagattg attctagacc ccaaaaaggg acgaaagttg aaatatatat aaatagaata
    21241 gaaactagct aactcccagt caattctggg agttttatgc gtaattgggc aaactttcta
    21301 ggttgtctat cttgctaaaa acaagaaaaa acggtatgat agaagagtga caacagaggt
    21361 aacagagatg aacgagacac agattcaaag agaaacacgt caggtagtgg aagatgtttt
    21421 agaaaagacc aatttgaagc agggggccct ttttgtttta ggtctatctt ctagtgaggt
    21481 gctaggtggt cagattggga aagaatccag tcaagagatt ggtgagctga tagtggagac
    21541 tatcttgggt attctaagta gtagaggtat ccatttagca gttcaaggtt gtgagcatgt
    21601 caatcgggct ctcgttgttg aacgtcaggt ggcagagcag tttggtctgg aaattgtcag
    21661 tgtccatcct actcttcatg caggaggttc ggggcagttg gcagccttta agtttatgca
    21721 ggatccagtt gaggttgaat ttatcaaggc tcatgctgga ttggatatcg gagacactgc
    21781 aattggcatg catgtcaagc atgttcaggt tccgattcgc cctattttga gagagattgg
    21841 tcatgcccat gtaacggcac tggctagtcg tccaaaatta atcggaggtg cgcgtgcgca
    21901 ctatccgcaa gacgctatta gaaagtcttg agaatgaata aaggagataa aagtgtttaa
    21961 aaaagaccgt ttttcaattc gtaagattaa gggagttgta ggctctgtat ttcttggaag
    22021 ccttttgatg gctccttctg tagtggacgc agccacctat cactatgtaa ataaagagat
    22081 tatttcacaa gaagctaaag atttaattca gacaggaaag cctgacagga atgaagttgt
    22141 atatggtttg gtgtatcaaa aagatcagtt gcctcaaaca gggacagaag catctgtttt
    22201 gacagctttt ggtttgctga ctgttgggag cttgctttta atctacaaga gaaagaaaat
    22261 tgctagcgtc tttctagttg gagctatggg attggtagtt cttcctagtg caggggctgt
    22321 agacccagtt gcgaccctag cgctggctag tcgagagggt gttgttgaaa tggagggcta
    22381 tcgctatgtt ggttatctat caggtgacat cctcaaaacg cttggcttgg acactgtttt
    22441 agaagaaacc tcagcaaaac ctggagaggt gactgtagtc gaagttgaga ctcctcaatc
    22501 aacaacaaat caggagcaag ctaggacaga aaaccaagta gtagagacag aggaagcacc
    22561 taaaacagaa gaaagtccaa aggaagaacc aaaatcggag ataaaaccta ctgacgacac
    22621 ccttcctaaa gtagaagagg ggaaagaaga ttcagcagaa ccagctccag ttgaagaagt
    22681 aggtggagaa gttgagtcaa aaccagagga aaaagtagca gttaagccag aaagtcaacc
    22741 atcagacaaa ccagctgagg aatcaaaagt tgaaccacca gtagaacaag caaaaggccc
    22801 agaacaaccc gtgcaaccta cacaagctga gcaaccaagg ataccaaaag attcatcaca
    22861 accagaagat cctaaagaag ataggggagc ggaagagaca ccgaaacaag aagatacacc
    22921 gaaacaagaa gatacacagc cagaagtagt agaaacaaaa gatgaggctg ctaatcaacc
    22981 tgttgaagaa ccaaaagttg aaacgcctgc tgtagaaaaa caaacggaac caaaagttga
    23041 acaagtaggt gaaccagtcg agccaagtga agacgaaaag gcaccagtct ctccagaaaa
    23101 gcaaccagaa gctcctgaag agaaggctgt agaggaaaca ccgaaaccag aagataaaat
    23161 aaagggtatt ggtactaaag aaccagttga taaaagtgag ttaaataatc aaattgataa
    23221 agctagttca gtttctccta ctgattattc tacagcaagt tacaatgatc ttggacctgt
    23281 tttagaaact gcaaaaggtg tctatgcttc agagcctgta aaacagcctg aggtaaatag
    23341 cgagacaaat aaacttaaaa cggctattga cgctctaaac gttgataaaa gtgaattaca
    23401 ggaacaatta agagttgctg aacaaaaaca acaagctgac tatagcgcta aaacttggag
    23461 ggaattcaaa attgctgaac ttcaagctaa agaaatcaac aaccaaacta caccacttcc
    23521 taaacaaagt gaaatagatg cagctactaa ggctcttcaa gacgctcttc aagctcttgc
    23581 tgtagataaa actgtattac aaaacgctat taacacagct aatagcaaac gtgaagaaga
    23641 gtatactgct cagacatgga aagcgttaga agatgctctt acagcagtga atcctgttaa
    23701 tgaagatgaa actgcaactc aaagcaaagt agacgaagct actagaaact tagaagaagc
    23761 tatcaataac ctagttctat taactgaaaa accggtatta acatttattg agactgataa
    23821 gaaagcatta gaacgtgaag tagttgctaa gtattctcta gaaaaccaaa ataaaacaaa
    23881 aattaaatca atcacagcta ctctgaaaaa aggagaaaca gttgttagca ctgtagagct
    23941 tataggcgat gatgtaacta atgaaactat aacctctgca tttaagaatc tagagtacta
    24001 caaagaatac accctatcta caactatggt ttacgataga ggtgacggtg atgtaacaga
    24061 aatcttagat aatcaaccaa tccaactaga tcttaaaaaa gttgagctta aaaatattaa
    24121 acgtacagat ttaatcaaat acgaaaatgg aaaagaaact aatgaatcac taataacaac
    24181 tgttcctgat gataagcgga attattattt aaaaataact tcaaagaatc aaaaaactac
    24241 attactagct gttaaaaata tagaagaaac tacggttaac ggaacacctg tatataaagt
    24301 tacagcaatc gcagacaatt tagtctctag aactgctgat aataaatttg aagaagaata
    24361 cgttcactat attgaaaaac ctaaagtcca cgaagataat gtatattata acttcaaaga
    24421 attagtggag gctattcaaa acgatccttc aaaagaatat cgtctgggac aatcaatgag
    24481 cgctagaaat gttgttccta atggaaaatc atatatcact aaagaattta caggaaaact
    24541 tttaagttct gaaggaaaac aatttgctat cactgagttg gaacatccat tatttaatgt
    24601 gataacaaac gcaacgataa ataatgtgaa ttttgaaaat gtagagatag aacgttctgg
    24661 tcaagataat attgcatcat tagccaatac tatgaaaggt tcttcagtta ttacaaatgt
    24721 caaaattaca ggcacacttt caggtcgtaa taatgttgct ggatttgtaa ataatatgaa
    24781 tgatggaact cgtattgaaa atgttgcttt ctttggcaaa ctacactcta caagtggaaa
    24841 tggctctcat acagggggaa ttgcaggtac aaactataga ggaattgtta gaaaagcata
    24901 tgttgatgct actattacag gaaacaaaac acgcgccagc ttgttagttc ctaaagtaga
    24961 ttatggatta actctagacc atcttattgg tacaaaagct ctcctaactg agtcggttgt
    25021 aaaaggtaaa atagatgttt caaatccagt agaagttgga gcaatagcaa gtaagacttg
    25081 gcctgtaggt acggtaagta attctgtcag ctatgctaag attatccgtg gagaggagtt
    25141 attcggctct aacgacgttg atgattctga ttatgctagt gctcatataa aagatttata
    25201 tgcggtagag ggatattcgt caggtaatag atcatttagg aaatctaaaa catttactaa
    25261 attaactaaa gaacaagctg atgctaaagt tactactttc aatattactg ctgataaatt
    25321 agaaagtgat ctatctcctc ttgcaaaact taatgaagaa aaagcctatt ctagtattca
    25381 agattataac gctgaatata accaagccta taaaaatctt gaaaaattaa taccattcta
    25441 caataaagat tatattgtat atcaaggtaa taaattaaat aaagaacacc atctaaatac
    25501 taaagaagtt ctttctgtta ccgcgatgaa caacaatgag tttatcacaa acctagatga
    25561 agctaataaa attattgttc actatgcgga cggtacaaaa gattacttta acttgtcttc
    25621 tagcagtgaa ggtttaagta atgtaaaaga atatactata actgacttag gaattaaata
    25681 tacacctaat atcgttcaaa aagataacac tactcttgtt aatgatataa aatctatttt
    25741 agaatcagta gagcttcagt ctcaaacgat gtatcagcat ctaaatcgat taggtgacta
    25801 tagagttaat gcaatcaaag atttatattt agaagaaagc ttcacagatg ttaaaaaaaa
    25861 cttaacaaac ctaatcacaa aattagttca aaacgaagaa catcaactaa atgattctcc
    25921 agctgctcgt caaatgattc gtgataaagt cgagaaaaac aaagcagctt tattactagg
    25981 tttaacttac ctaaatcgtt actatggagt taaatttggt gatgttaata ttaaagaatt
    26041 aatgctattc aaaccagatt tctatggtga aaaagttagc gtattagaca gattaattga
    26101 aatcggttct aaagagaaca acattaaagg ttcacgtaca ttcgacgcat tcggtcaagt
    26161 attggctaaa tatactaaat caggtaattt agatgcattt ttaaattata atagacaatt
    26221 gttcacaaat atagacaata tgaacgattg gtttattgat gctacagaag accatgtcta
    26281 catcgcagaa cgcgcttctg aggtcgaaga aattaaaaat tctaaacatc gtgcattcga
    26341 taatttaaaa cgaagtcacc ttagaaatac tatactccca ctactgaata ttgataaagc
    26401 acatctttat ttaatttcaa attataatgc aattgccttt ggtagtgcag agcgattagg
    26461 taaaaaatca ttagaagata ttaaagatat cgttaacaaa gctgcagatg gttatagaaa
    26521 ctattatgat ttctggtatc gtctagcgtc tgataacgtt aaacaacgac tactaagaga
    26581 tgctgttatt cctatttggg aaggttataa cgctcctggt ggatgggttg aaaaatatgg
    26641 ccgctataat accgacaaag tatatactcc tcttagagaa ttctttggtc ctatggataa
    26701 gtattataat tataatggaa caggagctta tgctgctata tatcctaact ctgatgatat
    26761 tagaactgat gtaaaatatg ttcatttaga aatggttggt gaatacggta tttcagttta
    26821 cacacatgaa acaacacacg tcaacgaccg tgcgatttac ttaggtggct ttggacaccg
    26881 tgaaggtact gatgctgaag catatgctca gggtatgcta caaactcctg ttactggtag
    26941 tggatttgat gagtttggtt ctttaggtat taatatggta tttaaacgca aaaatgatgg
    27001 gaatcagtgg tatattacag atccaaaaac tctaaaaaca cgagaagata ttaatagata
    27061 tatgaagggt tataatgaca ctttaactct tcttgatgaa attgaggctg aatctgtgat
    27121 ttctcaacaa aataaagatt taaatagtgc atggttcaaa aaaatagata gagaataccg
    27181 tgataacaat aaattaaatc aatgggataa aattcgaaat ctaagtcaag aagagaaaaa
    27241 tgaattaaat attcaatctg ttaatgattt agttgatcaa caattaatga ctaatcgcaa
    27301 tccaggtaat ggtatctata aacccgaagc aattagctat aacgatcaat caccttatgt
    27361 aggtgttaga atgatgaccg gtatctacgg aggtaatact agtaaaggtg ctcctggagc
    27421 tgtttcattc aaacataatg cttttagatt atggggttac tacggatacg aaaatgggtt
    27481 cttaggttat gcttcaaata aatataaaca acaatctaaa acagatggtg agtctgttct
    27541 aagtgatgaa tatattatca agaaaatatc taacaataca tttaatacta ttgaagaatt
    27601 taaaaaagct tacttcaaag aagttaaaga taaagcaacg aaaggattaa caacattcga
    27661 agtaaatggt tcttccgttt catcatacga tgatttactg acattgttta aagaagctgt
    27721 taaaaaagat gccgaaactc ttaaacaaga agcaaacggt aataaaacag tatctatgaa
    27781 taatacagtt aaattaaaag aagctgttta taagaaactt cttcaacaaa cagatagctt
    27841 taaaacttca atctttaaat aattgaaatc tctcgtctgc tttgcggatg agggttttct
    27901 tattttatgc tatacttaag gtatgcatag aaaaacagtg attgatttta ggactttggg
    27961 ggagagatat acctttacca agcctattaa agagttgaaa acgagaaatg tagaagaagt
    28021 ggcagatttg ctggcacaag tggaaagcta ccaagagcaa ggttattatg tggtggggta
    28081 tgtcagctac gaggctgcac ctgcttttga ggaaaaatta gcagttcaca aggatcccct
    28141 actgggagag tacctgcttt attttactgt tcatgatagc gtagaaactt cctctattcc
    28201 tctgacttat gaggatattg atttgccctc aaattggcag gaagtaacgt ctgcagcaga
    28261 ctatgaaaag gccattgccc aaattcacca tcatttacgg cagggagata cctatcaggt
    28321 caactacacc gtccaactta agcaaaagtt aaatgccaat ccttttgcca tctacaatcg
    28381 tatggtggta gagcaggagg cgggctacaa tgcctatgtg gaacatgacg agatggcagt
    28441 gatttccatg agcccagagc tcttttttga gcaaaatgat cgcgagttga caacacgacc
    28501 aatgaagggg acgactcagc gtggggtaac tgaccaagaa gatcttgaac aggccagttg
    28561 gttggaacag gatcccaaaa atcgctctga aaatatgatg attgtggacc tcttgcgcaa
    28621 tgatatgaac cgtatttctg aagttgggag cgagcacgtg gagcgtctgt gtcaggtaga
    28681 gcagtattca actgtttggc agatgacttc gaccatcaag agtcagttgc gagaggatgt
    28741 ggaccttgtt gaaatcttcc gctcactctt tccttgtggt tccataacgg gtgcaccgaa
    28801 aattgcgaca atggagatta tcaaggactt ggagcctcaa ccgcgtggag tctactgtgg
    28861 aacgattggt ctcttgcttc caaatggacg acggattttt aatgtggcca ttcgtaccat
    28921 tcaacttcac aaaggtcaag ccatttatgg agttggcgga gggattactt gggatagcac
    28981 atgggaatct gaataccgag aggttcatca aaaggcagca gttctttatc gtaaacaagc
    29041 tcgcttccaa ctgattacga caggggaaat cagccagaag aacctgttgt ttgaagatca
    29101 acatctggaa agactgagaa aagctagtcg ttattttgcc tttccttttg atgcagaaga
    29161 cttgggacac aagattgagg aagagtgtca ggattgtgaa gctaatcgag attaccgctt
    29221 gcgaatcagc cttagcaaat ctggagagat agaagtcaat cgtcaagtat taacccctct
    29281 cagtacaagc ttttgtcagg cccaagtctg ccttcaggaa gctgctttga atcaatcctt
    29341 tacctacttt aaaaccactc accgaccgca tttgagccta ggagaacaag agaagattta
    29401 ccacaataag tcaggagaac tgcttgaaac ctctatagga aatttggttc tgaaaatcgc
    29461 tggaaaactc tacacaccgc ctatccgact tggaatcttg ccaggaattt accgtcagta
    29521 tttgctagaa acaggacagg tagaagagaa agtcttgacc ttggcagatt tagcccaagc
    29581 agaagctatt tacggctgta atgcagtgag aggcttgtat gagttgcaag tgataggatt
    29641 gtgagtttta gctattaata gtttttaata tatattaaaa tatattggtg tttacttttg
    29701 atgagatatc atatttgtgt tataatgtaa ccgtaaacaa tagaaattta aaggagattt
    29761 ttgatgaaat caaaaatagt tttgggagct tcgctagcga tcgcaacact tagcttagta
    29821 tctcttgtcg agattgaagg actctcaccg tttttaatag agaatgttag cgcaaatact
    29881 cattctgcaa ataaagttat taatcataaa gtaagtattt acttagaaaa tgctgatgaa
    29941 ggtaaaggtc taactgtaaa cttttcaaca gacagtgtta gtccaaattt atttgatgag
    30001 ttcgaaaaaa agagtggaat tacaataact actatgttag tgaatgctaa gacaggtgaa
    30061 gttgtagaaa aaagattaac accaagcgtt tttttacgtt ccaatgattt aaccagtggg
    30121 accatatctt cgtttatttt tagtgaatat cctgatggag aatataaata tgttgtgtct
    30181 aaaggagact ttatcgatcc taagactcag tttaaacatc agtatagagg agaatctcca
    30241 gtttttagaa tacgtaatcg aaaatatgtg gagttgggaa caactgataa aaaattagat
    30301 gaaagacgtg ataatagcgt ttataaagat ggggttgttg aacacaaggt aaatttaagt
    30361 ttaacaagtt atcaaggagg taatggagtt actgcaattt tttcaactga tagtgttaac
    30421 tctaacttac ttaattcttt tggtgaaaag gctaaaaaag ttttgattag gtctaagtta
    30481 attaatgtta agactggcga ggttattgat gaaacgtttt ctccaaaagt aagtttaacc
    30541 tctaaaattt tgaaaagtgg ttctacagca gtattttatt ttatagattt aactgatggc
    30601 gaatataaat atgttgcgta tgaaagccag caatatactg atcctcaaac aacattgact
    30661 catcagtata gaggagaatc tcctattttt agtatcaaag atggaaaatt ttctggttta
    30721 gtatctgcct caaaaccaga cgaaaacccg aagccaacgc caaaaccgga tgagaaacca
    30781 aaaccttcag caccacaaca ggagaaaaca aaacctacag ttcagtctgg ttgggtaggt
    30841 tcatcttatt atcaaaatgg taaaaaagtc actagtaagt ggatttttga taaaaaatat
    30901 aattcatact tctatctaga tgcatcagga aattatgttc aaaacgcttg ggtaggtaac
    30961 tattatctca aatcaggcgg atacatggct aaaagtgagt ggatttatga taagaactat
    31021 ggttcatact actatctaac atcagaaggc agctacgctc gtaacacttg gtcaggcaat
    31081 tattatttga agtcaaatgg taagatggct aaaagtgagt gggtatacga tagtaactac
    31141 aaatcatatt actacttgac atcagaagga agttatgctc gtaacacttg ggtaggcaat
    31201 tactatctta aatcaaacgg taaaatggct gttaatgaac gtacaccaga tggttatcgt
    31261 gtagatggtt caggtaaatg ggttaaataa gaaactaaaa aataggataa taggtaatat
    31321 cagatgaata aaaaaaatta ttttcatgtg ctttagcatt ttcaacgatt ggaacattgt
    31381 caacgattga taaatcagga gttcttcctt tttcagcgca aacggtgcag gctgacatac
    31441 aaacgcttac cccaatggca aaatattata ttattcttcc gaaggatgca gaaatatata
    31501 aaacttggag aggtactgtc aatattccca ttattgatgc tacaaaaact actccagaat
    31561 tatcttattt caaagaagat catcgcaact atatagctaa tgagaataag tctggtgcca
    31621 attacataga gtggaaggga acagtagaag agtttaaaga ggccattaag aagttgactg
    31681 ataaaaaatc aactactgca acaccaaaaa aggatgaaaa gccaacacca aaaccggatg
    31741 agaagccaaa accaacacct acagttcagt ctggttgggt aggttcatcc tattatcaag
    31801 atggtaaaaa agtcattagt aagtggattt ttgataaaaa atataattca tacttctatc
    31861 tagatgcatc aggaaattat gttcaaaacg cttgggtagg taactattat cttaaatcag
    31921 gcggatacat ggctaaaggt gaatgggttt atgatgccac ctatcaagct tggtattatt
    31981 tgacatcaga tggttcttat gcttacagta catggcaagg aaattactat ctaaaatcgg
    32041 atggtaaaat ggctgtcaat gaatgggttg atggtggacg ttattatgtt ggcgctgacg
    32101 gagtttggaa ggaaggtcaa gcaagtacag cttcttctag taatgatagc aatagtgaat
    32161 attctgctgc tttaggaaag gcaaaaagtt ataattcgtt attccacatg tcaaaaaaaa
    32221 acgtatgtat agacaattaa cttctgattt tgataaattt tcaaatgatg cagctcaata
    32281 tgccattgat cattagatga ttaacagata ctggtaggcg aaaaaattcc ttataattca
    32341 tttacgcaaa cctttgcata agtgaatgga ttttgatata ctagtactgt aagcattttc
    32401 aattactaca caatgaaaaa ggagaatatg atgagtcaaa agattattgg gattgacctt
    32461 ggtggaactt ctatcaaatt tgcaatctta acaacagcag gagaaatcca aggaaaatgg
    32521 tcaatcaaga ccaacatttt ggatgaggga agtcatatcg ttgatgatat gattgagtct
    32581 attcaacatc gtttggactt gcttggattg gcagcagcgg acttccaagg cattggaatg
    32641 ggatcaccag gtgtggttga ccgtgacaaa gggactgtta tcggtgccta caacttgaac
    32701 tggaaaaccc ttcaaccaat caaacaaaag attgaaaaag ctttgggcat tccatttttc
    32761 atcgataatg atgccaacgt agcagctctt ggtgagcgct ggatgggtgc tggagataac
    32821 caaccagacg ttgtctttat gacactcggt actggtgttg gtggcggtat cgtcgcagaa
    32881 ggcaaattgc ttcacggtgt tgctggtgca gcaggtgagc ttggtcacat cactgttgac
    32941 tttgaccagc caatctcatg tacttgcggt aagaaaggct gccttgagac agttgcttca
    33001 gcaacaggga ttgtcaactt gactcgtcgc tatgccgatg aatacgaagg cgatgcagcc
    33061 ttgaaacgct tgattgataa tggagaagaa gtaactgcta agactgtctt tgatctcgca
    33121 aaagaaggag acgaccttgc tttgattgtt taccgtaact tctcacgtta cttgggaatc
    33181 gcttgtgcta acattggttc aatcctaaac ccatcaacaa tcgtcatcgg tggtggtgtg
    33241 tcagctgcgg gagaattcct tctacaaggt gttcaaaaag tttacgatga aaatagtttc
    33301 ccacaagtac gcacatctac taaattagct cttgcaactc taggaaatga cgctggagtt
    33361 atcggagcag catcacttgt attgcaataa gataatgaga gaggaaaatg ctaacctaga
    33421 gttagtaatg ttcctctttt attttttatg ctatactagt taggacaatg aatgaggtga
    33481 gagtaaatga caaaagcaga tacgattttt aaagagaata ttgaacgcat tctaaaggaa
    33541 ggtgttttct cagagcaggc tcgtcctaag tacaaggatg ggactgttgc taattccaag
    33601 tatgtaactg gtgccttttc cgagtacgac ttatctaaag gagaatttcc tatcacaacc
    33661 ttgcgtccca ttgcaatcaa atccgccatc aaagaagttc tctggattta ccaagaccag
    33721 tcaaatagct tagaagtgct taatgacaag tacaatgttc actactggaa tgactgggaa
    33781 gttggagaca cgggaaccat tggtgagcgc tatggtgccg ttgttaagaa acacgacatt
    33841 atcaataagc ttctcaaaca gttggaaacc aatccttgga accgccgcaa tattatttcg
    33901 ctctgggatt accaagcttt cgaagaaaca gatgggctgc tcccgtgcgc ctttcagacc
    33961 atgtttgatg ttcggcgtgt tgatggggaa atctatctgg atgcgacctt gacccagcgc
    34021 tccaatgata tgctggtggc ccaccacatc aacgctatgc agtatgtggc tttgcagatg
    34081 atgattgcta aacattttgg ctggaaggtt gggaagttct tctacttcat caacaacctc
    34141 catatctatg ataatcaatt tgaacaagct caggaattgc tccgtcggga gccgtcaaac
    34201 tgccaaccac gcttggtttt aaatgttcct gatgggacta atttctttga tatcaaagca
    34261 gaagattttg agttggtgga ttatgaccct gttaagccac agttgaagtt tgacctagct
    34321 atttaaaaga atagaaaaaa gaagttgaga ataatcccaa cttcttttgt ttcttaacgt
    34381 gatacgcggc gacgagctgc ttttttacgg ttttcttcga tgaaagctgc tttttgctct
    34441 tctggttcga ttactttctt tttaaatgcg tatactgcac ctgcaacggc agcgacagtt
    34501 cctgcgacac ctgttacaag acctttagcg aatcctttag ccatgagtct tcctccttta
    34561 tattctcaat cagccagcct cctcaagagg tcacattttt ctgactgacc tttttgtgtt
    34621 ataataatag taacgaaaaa atgggaattt ttcaaggaaa aaagatgaaa acaaaaataa
    34681 ttgtgattgt tggaccgact gctgttggaa agacggctct agctattgag gttgcaaagc
    34741 gctttaatgg cgaagtggtt agtggagata gccagcaagt ctatcgagga cttgatattg
    34801 ggacggccaa ggctagtcca gaagagcagg cagctgttcc tcatcattta atcgatgtta
    34861 gagagataac cgagtcttac tcggcttttg attttgtttc agaagctaag atgactattg
    34921 aggatattca gagccgtggc aagctagcca ttatcgccgg tgggactgga ctttatatcc
    34981 agagcttgct agaaggttac cacctaggtg gggagactcc tcatgaggag attttagctt
    35041 atcgagctag tttggagcca tattcagatg aggaattagc ccatttggtg gagcaagcag
    35101 gccttgagat tccccagttt aatcgtcgtc gtgctatgcg tgccttagaa attgcccatt
    35161 ttggtcagga tttggaaaat caagagatct tgtatgaacc gctgattatc tgcttggatg
    35221 atgaacgtag tcaactttat gagcgtatca accaccgagt ggatttgatg tttgaggctg
    35281 ggcttttgga tgaggccaag tggctgtttg accattcccc taatgtacag gctgctaaag
    35341 gaattggcta taaggaactc tttccttatt tccgtggaga gcagaccttt gaggaagctc
    35401 gtgagagtct taaacaggcg acccgtcgtt ttgccaagcg tcagctgacc tggttccgta
    35461 atcgcatgca ggtcaccttt tatcagattg gagaatctgg tgtacaagac cgcattttaa
    35521 gccagataga ggagttttta gatgattgaa acggagaaaa aagaggagcg agtcctgctg
    35581 attggtgtgg aattgcaggg tatggacagt tttgacctct ccatggaaga attggctagt
    35641 ttagcgaaaa cggcaggggc agtcgttgta gatagctaca gacaaaaacg tgaaaaatat
    35701 gattccaaga ccttcgtcgg ctctggtaag ttggaagaga ttgcgcttat ggtggatgca
    35761 gaagaaatca ctactgtcat cgtcaacaat cgtctgaccc caaggcagaa tgtcaatcta
    35821 gaggaagttc tcggtgttaa ggtcattgac cgtatgcagt tgattttgga tatctttgcc
    35881 atgcgggctc gaagccatga agggaagctc caagtccacc tagcccaatt caaatacctc
    35941 ttgcctcgct tggttggtca ggggattatg ctcagccgtc aggcaggggg aattggttcc
    36001 cgtggtcctg gtgaaagcca actggagctg aaccgtcgta gcgttcgcaa tcaaatcacg
    36061 gatatcgagc gccagcttaa ggtggttgag aaaaatcgtg cgactgtcag agaaaaacgt
    36121 ttggagtcta gcacttttaa gattggtttg attggttata ctaatgctgg gaaatcaact
    36181 atcatgaaca tcttgaccag taagacccag tatgaagcag atgagctctt tgcgactctg
    36241 gatgcgacaa ccaagagtat tcatctggga ggcaatctcc aagtaacttt gacagatacc
    36301 gttggcttta tccaagattt gccgacagag ttggtgtcca gtttcaagtc aaccttggaa
    36361 gaaagcaagc atgtggacct tctggttcat gttatcgatg ctagcaatcc ttaccacgag
    36421 gagcatgaaa aaacggttct ctccatcatg aaagacctgg acatggaaga tattcctcac
    36481 ttgacgcttt ataataaagc ggatttggtg gaggatttca cgcctaccca aacgccatat
    36541 accctcattt ctgccaagtc tgaggacagt cgtgaaaact tgcaagcatt attgctagat
    36601 aagattaagg aaatttttga agcatttacc ctgcgagtgc ctttttcaaa gtcctacaag
    36661 attcatgatt tagagagtgt tgcaattctg gaagaacgtg attatcagga agacggcgaa
    36721 gtgattacag gctacatttc cgagaaaaat aaatggaggt tagaagaatt ttatgactga
    36781 tattaaaact ttggctctaa agtatggagg ttatacaagt ctggacaagg tctatctgga
    36841 tcagcttcta gctggtaaaa cagatcagga gcagttaaca cttattacac ctccgccaag
    36901 tgttgttaat gcctactttg cagaactcta tcagaaaaag agtcctcagg ctgcgacgga
    36961 ttattttgca gaactcagtc aggaactgaa tctttacaat actgagccaa gtttcaccct
    37021 agaaaataag ccttttattc ggcttaatct gtctggtaaa tcctttggtt tttgttatga
    37081 gagtgacggc cttggtcgga ttttctttga aaatgaggag aaaatctcgg atgacttgct
    37141 ctttgaaatt gcgcaaattt tcccccatca attagtcttt gaagagtctg gtaagattta
    37201 catgaagcct gtcgaggacg aggaagttat cagcctagaa agtctcacag ctttgactga
    37261 tttggaaaga ttggctgatg gtcgaaaacg tctcaaaggc tacagccaag aggatttatt
    37321 gcaagaagct gctgcttttt ctggcaaacg ctatttccga tcggaaaacc gcacagccat
    37381 gttatatatt gattaattag aaagtatcga atggatattc aatttttagg aacgggggct
    37441 ggtcagccct ctaaagcccg caacgtttca agtctcgccc tgaaactttt ggatgagatt
    37501 aacgaagttt ggctctttga ctgtggagaa ggtacgcaaa atcgcattct ggaaaccaca
    37561 attcgaccac gtaaggtcag caaaatcttt attacccatc tgcatggaga ccacattttt
    37621 ggtttgccag gtttcctttc tagccgtgcc tttcaggcca atgaagagca gacagatttg
    37681 gaaatctacg gacctcaagg aatcaagtca tttgtcttaa ccagccttcg tgtgtcaggt
    37741 tctcgtctgc cctaccgcat tcatttccat gagtttgacc aagattctct aggtaaaatt
    37801 cttgaaaccg ataaattcac tgtgtatgca gaggagctgg accacactat tttctgtgtt
    37861 ggctatcgtg tcatgcaaaa ggatctagaa gggacgctgg atgctgaaaa actcaaggct
    37921 gctggtgttc cgttcggccc gctttttggt aaaatcaaaa atggccagga tcttgttttg
    37981 gaagacggaa ctgaaatcaa ggcagcagac tatatctcag cgccacgtcc aggtaagatt
    38041 atcactattt taggagacac tcgaaaaacg gatgccagtg tgcgtctggc tgtcaatgca
    38101 gatgtcctag ttcatgagtc cacttatggc aagggtgatg aaaaaattgc tcgtaaccat
    38161 ggtcactcaa ctaatatgca agctgcacaa gtagcggtag aagcaggtgc caaacgcctc
    38221 ctactcaacc atatcagtgc ccgtttcctc tcaaaagata ttagcaaact caagaaagac
    38281 gctgccacaa tttttgaaaa tgtccatgtg gtcaaagact tggaagaagt ggaaatctag
    38341 cagtcacaga aaggataagt atgcctacta ttctcattac cggagctagc ggtggtctag
    38401 ctcaagaaat ggtcaaactc ctgcccaatg accaactcat cttgcttggt agaaataagg
    38461 aaaaattagc ccaactctac ggaaattatt cccatgcaga attgattgaa attgatatta
    38521 ccgacgattc agccctagaa gctctggtaa ctgatcttta tctccgctat ggcaagattg
    38581 atgtcttgat taacaacgct ggttacggga tttttgaggg atttgaccag attgctgata
    38641 aagatattca ccagatgttt gaggtcaata cctttgccct gatgaatctg tctcgtcacc
    38701 ttgcggctcg tatgaaggaa agcagcaaag ggcatatcat caacatcgtc agcatggcag
    38761 gtctaatagc tactggcaag tctagtcttt actcagcgac caagtttgcg gctattggtt
    38821 tttcaaatgc tctgcgactc gaacttatgc cctatggagt ctatgtgaca acagtcaatc
    38881 caggtccaat ccgaacagga ttttttgacc aagctgaccc agatggaact tatcttaaat
    38941 cggttgaccg cttcctctta gaggcagatg cagtggctaa aaagattgtc aagattatag
    39001 gcaaaaataa acgagaactc aatctcccga ttttgttgaa cctagcccat aagttttata
    39061 ctctctttcc caagctagct gataagttgg caggggaaac ttttaattat aagtaaaaag
    39121 aaccaatgtg caggttgttg ctagcctaca tattggttct tatcatttct caactatcaa
    39181 actgaacttc ttctaggaga tagtcgataa agcgttcgcc catcttagat aggctggttt
    39241 tctcatgctg gatatagacc agctcaatcg ggtcatcaat atccagtggg atagaaacga
    39301 tattgtctcc gtttaggttg ctgttcaaaa tccctgtcgc aatggtataa ccatccaaac
    39361 caatcaagag attaaagagg gtggcacggt cactgaccac aatggatttc ttgtggtgtt
    39421 cttgagaaag aatctcttct gaaaagtaga aggagttgtg cgtcccttgg tcatagctga
    39481 ggtaagggaa attctccaaa tcagacagtt tcaccttgtc tttctttgcc agagggttgg
    39541 tcttgctgac aaagatatgc ggttgcgctg tgaagagatg gtgggatagc aggtgattgt
    39601 catccagcat cttggttaaa acatcacggt tgtagctgtt caaaaatagg acaccgacct
    39661 cactacggaa attcttgacg tcgtcaataa tctcccaagt ccgagtttca cgaaggaaga
    39721 gttcgtattt ctccatatcg cttttcttga gcaaagagac aaaggcattg accacaaagg
    39781 catagtgttg agacgaaacg ctaaagagtt cgcggtgggc gacaggattt ttatagcgtt
    39841 cctccagaag ctgggtctgc tcgacaacct gacgggcata ggagagaaac tccatcccat
    39901 cacgggtcaa ggtgattccc ttgggattgc ggataaagat ctcaatgccc atttcatttt
    39961 ccaaatctcg cactgcattg gagagacttg gctgagtgat aaagagttgc ttggctgcct
    40021 cattcatgga gccagtttcg acgattttga taatataatg taattgttga attctcatgt
    40081 ttttattgta ccatacttgc cttagaatcg ctaaagaaga taggaaaata aggagcattg
    40141 tgtgagtctc ttcttgaaaa aaacacaaaa ttttgctaga atgagtctta tgaaaacatt
    40201 ctatgatgtg cagcaattcc tcaaacgatt tggtattatt gtttacatgg gaaaacgctt
    40261 atatgatatt gaactgatga agttggaact atctcggatt tacgatgcag ggttgatgga
    40321 taaattagac tatctagagg cagaagcagt tcttcgcaga gagcacaagg tagaattgga
    40381 ttatattgag aaaaatggag aaaagaacta atggttactt ggattttgtg ggcacttata
    40441 ctagcaatgt tggcgtggat gggctttaac tatcttcgta ttcgccgtgc ggctaaaatt
    40501 gtggacaatg aggagtttga agccttgatt cgtacgggtc aattgattga tttgcgcgac
    40561 ccagcagaat tccacagaaa acatatcctt ggtgcacgca atattccttc aagtcagttg
    40621 aaaactagtc ttgcagccct tcgtaaagat aaacctgtcc ttctctacga aaaccaacgt
    40681 gcgcaacgag ttacaaatgc agctctttac ttgaaaaaac aaggtttttc tgagatttat
    40741 atcctttctt atggcttgga ttcttggaaa gggaaagtga agactagcta accttatttc
    40801 caaattagtc gaatgatagg atgaagctat tgttttatag tataattaat ttgtataaaa
    40861 tttaaggagt tcttagaaca tgaaagaaaa gaagaaaaat ccactttttg tgggtatctt
    40921 gtcgattatt cttggtttgt tatttccaat tgtaggcctg attttgggta tcataggatt
    40981 ggtcttggct atttcatacc aaaaagagtc acaattagac tataaaatag aaaagattct
    41041 taatatctaa ggaattgtga tttctgtagt taactggatt gtagcaatcg ccttaatttt
    41101 tcggtaaata aaagaaaaaa gctttagttt taaagctttt tttgttttat cgactcatct
    41161 ctaaatagtt tttaatgatt tgtaactctt tttggttcaa agggcggtag ttaccttctg
    41221 ctaaatctgg gttcaatgtg aagtccccaa attggattct tttgaggcta gtcaccttaa
    41281 caccaaccga gaggaacatt ttcttgattt gatgaaattt tccttctgaa atggtgatag
    41341 aggcttgact gagggaggga cttgcagata gaatctctag ttttgcgggt ttacagacag
    41401 taccatctaa aaagacaatt cccttttgaa aggcttggat atggtcaggt gttagaagtc
    41461 cattaacctg gacttggtaa gtcttatcga catgatattg gggatggagg agctgaaagc
    41521 ccaagggacc gttatcggtc aagaggagga gtcccgttgt atctcggtcc agtcggccaa
    41581 cggcatagag cttgtcagac tggatgtcag atggaagcag gtccatgacg gtcggaagtt
    41641 ccttgtcttt gttggctgta acgacaccag caggtttatg aagcataaga taggtgtgtt
    41701 catagccttg aatgattcga tcctgaaaaa ggagttcttg tagtcctgta tcgatatttt
    41761 gagctaggga gcgggctggg caaccatcga ctagaatttc ccctctgagg agtgcttgct
    41821 tcatggcctt tcggctgatt ttttcttggg ctaataaatt atctaaacgc atactgtgcc
    41881 tatcttatca taagtcgctc gctttgaaaa ggcttgacgt gaaaagaaaa gcagagtgaa
    41941 aacatttaca cttgcttgag ttatgttatt tacttgaaat tatggtataa tcgttcagtt
    42001 agaaaataaa ttttgaatat tatagaggaa atcatgacaa aattaagaga agatatccgt
    42061 aacattgcga ttatcgccca cgttgaccac ggtaaaacaa ccctggttga cgaattattg
    42121 aaacaatcag aaacgcttga tgcacgtact gaattggcag agcgtgctat ggactcaaac
    42181 gatatcgaaa aagagcgtgg gattaccatc cttgctaaaa atactgccgt tgcttacaac
    42241 ggaactcgta tcaacattat ggacacacca ggacacgcgg actttggtgg agaagttgag
    42301 cgtatcatga aaatggttga cggtgttgtc ttggtcgtag atgcctatga aggaaccatg
    42361 ccacaaactc gtttcgtatt gaaaaaagcc ttggaacaag accttgtccc aatcgtggtt
    42421 gttaacaaaa tcgataagcc atcagctcgt ccagcagaag tagtggatga agtcttggaa
    42481 cttttcatcg agcttggtgc agatgacgac cagcttgatt tcccagtggt ttatgcttca
    42541 gcgatcaacg gaacttcttc attgtcagat gatccagctg accaagaagc gactatggca
    42601 ccaatctttg acacgattat cgaccatatc ccagctccag tagataactc agatgagcct
    42661 ttgcagttcc aagtgtcgct tttggactac aatgacttcg ttggacgtat cggtatcggt
    42721 cgtgtcttcc gtggtacagt taaggttggg gaccaagtta ccctttctaa acttgacggt
    42781 acaactaaaa acttccgtgt tacaaaactc ttcggtttct ttggtttgga acgtcgtgaa
    42841 atccaagaag ccaaagcggg tgacttgatt gccgtttcag gtatggaaga catctttgtc
    42901 ggtgaaacca tcactccgac agatgcagta gaagctcttc caatcctaca catcgatgag
    42961 ccaactcttc aaatgacttt cttggtcaac aactcaccat ttgctggtaa agaaggtaaa
    43021 tgggtaactt ctcgtaaggt ggaagaacgc ttgcaggcag aattgcaaac agacgtttcc
    43081 cttcgtgttg acccaactga ttcaccagat aaatggactg tttcaggacg tggagaattg
    43141 cacttgtcaa tccttatcga aacaatgcgt cgtgagggct atgaacttca agtatctcgt
    43201 ccagaagtta tcgtaaaaga aatcgacggt gttaaatgtg aaccatttga acgtgtacaa
    43261 atcgacactc cagaagaata ccaagggtct gttatccaaa gcctttctga acgtaaaggt
    43321 gaaatgttgg atatgatttc aactggtaat ggtcaaactc gtttggtctt ccttgttcca
    43381 gcgcgtggtt tgattggata ctcaactgag ttcttgtcaa tgactcgtgg ttacggtatc
    43441 atgaaccata ccttcgacca gtacttgcca ttgattccag gggaaattgg tggacgtcac
    43501 cgtggtgccc ttgtttctat cgatgctggt aaggctacaa cttactcaat catgtctatc
    43561 gaagaacgtg gtacgatctt tgtcaaccca ggtactgagg tttatgaagg aatgatcatc
    43621 ggcgaaaact ctcgtgaaaa tgacttgaca gttaacatca cgaaggcaaa acaaatgacc
    43681 aacgttcgtt cagctactaa ggaccaaaca gctgttatca agacgcctcg tatcttgaca
    43741 cttgaagagt ctcttgagtt cttgaacgac gatgagtaca tggaagtaac gcctgagtct
    43801 atccgtttgc gtaaacaaat ccttaacaaa gcagagcgtg agaaagctaa caagaagaaa
    43861 aaatcagctg aataagagct agaaagagag aaagatggtc tatttagtcc taggaatttt
    43921 actgctccta ctctatgtat ttgcgacacc agaaagcatt aaagggactg tcaatatcgt
    43981 cgctatggta tgtattttag tggcactctt gattttattg gttctatctt ttctgaaaat
    44041 ttttcaatta ccaacagaaa tattcctagc aatagccatg ttgatcctag cttactttag
    44101 tgtgagagac atcacactca tgccagtcaa aaaaagtaaa agaagataaa aaagagagtt
    44161 tcggctctct ttttgctagg aattttacaa tagtttgaat tgctttttag ttaacaccat
    44221 ctcttttact tggatagtat gaatgggaaa aacttgaata aaattcgtta atggcatcta
    44281 ttttatattt ggttagtact ggttgcatat tattttgaaa taaaactact atataatatt
    44341 attcacagag gtaatatagt aaaatatcta aaaaattcga ttttttcctt gacaacaaat
    44401 aataaaaatg ctattcttat tatataagaa atcggtttca aaaaagagag aggaggattt
    44461 attttgttgc attgttgctc agggtgtgct ttttttgaaa ggaaaaataa aatgaaaacg
    44521 aaaaaacata gattacttgc tctagctctt atttcaagct ttacattatt gggagctgca
    44581 tcagctgctg tacaatatcc agatggagga gtatggacat atggagaagg ttcaggaggt
    44641 ggttgggctt tttcaaatta ctatcatggt aaaaaatatc attattcttc tgttgtaagt
    44701 aaatgggata gtcattcaga taaaggatca gcacctgcag ggaaaacttc agaggcttgg
    44761 atttggacta aatttgggga acaagtatca ttttactatg actatgacta atatttagtt
    44821 ttcttagata attccccttg taagaaatta cagggggaat tttgtttaca aggagtctac
    44881 tatgaagaaa ctattcatat tactatcaac tttttttctc agcttcttct ttgcttggat
    44941 tattgtctta cgtgcgccac aatatttata tgcaagctat gattccgtta ctttacttcg
    45001 tgtcaaaaaa gaggctcagg aaccgactcg tgaggtattt gaacaggaat tggagaagtt
    45061 tgtaaactca gaacagagtt taatagctag gagaattgta gaaccgagta aggatgggac
    45121 gactcacttt acttatgcaa cttatggtca gggaacatta ccaaaacaat tccaagaagc
    45181 tagccaagaa agtcgtgaac gtagtgatcc gctaaatagt tatctccttt tatcaggctc
    45241 cttgacaaaa gaaaagctag ctgataaatt aggagattta ggttataaag caattgctga
    45301 ccgaaagaca cctccctatt ctcttgcttt tcgaatgtta ctaaatcccc ttattttaat
    45361 tagtttagca atatttggct tatctttctt tgctttagtg attatcactc ggattaagga
    45421 aatgagagca gcaggtataa aactcttttc tggtcagact ctcttatcca ttatggggca
    45481 ttctttatct actgatatta agtggctcct tctatcagcc ctcctttcct tcctaggtgg
    45541 gggagtcgtt ctttttagtc aaggtttgtt ttatcctatc ttgttagcca cctatggttt
    45601 tgggattagt ttctatctgt tgtttttatt ggcgatttca attttactaa tgctccttta
    45661 tctaatgagt ttgagttaca aagcattagt tcccgttatt aagggaagat taccccttaa
    45721 acgcctgatg attttaaccc tattgtgtca gttggttgct gtctttacag tgggatacgc
    45781 tgttaagaca ggtttgacgt cttaccaacg attgaaagaa cttgaaattt caaaacaagc
    45841 atggcatgac agagtagact attatcaaat ttcttttggc ttaggtgaca gagtaaatga
    45901 tacagaaaat cagaataagt ggtatgaatt ttccaaagaa gcagttgaaa aagaacaggc
    45961 tctatttgta aaagagaatc tcattcattt tgcaaatcct caaggaaaaa atgaaaacgg
    46021 ggaaacactg gatacctata gtccagatgc taatgttctc tatgtgagtc caagttattt
    46081 agacaaggaa aatgtggctg taaatgatga gactagacag aaactagctc atcttcaaaa
    46141 aggggaattt ggactcttat taccagaatc tcttcgttca caggaagcag aacttaagaa
    46201 agtttttgaa gaacgtttga actattacgg aaaatcaagc gaggataaag acgctccttt
    46261 agagtatgaa atgagagcga ttgttagcta tcttccaaca ggacaaaaac gctttgttta
    46321 taataacggt gaaagtccag tatctattca gtacttaacc gatccgattt tagttgtatt
    46381 tactccaaca tctacaggtg atagtttcat ttcaaaatat gtttggtcta tcaatgctgg
    46441 aaaacaactc tttatcaaag gatatgagag tgggctagaa ctcttaaaga aagctggaat
    46501 ttatgagcaa gtatcctatc ttaaagaagg aagaagtgtt tatctaactc gttataatga
    46561 agttcaaact gaaacagcaa ctttaatctt aggagctatt gttgggatag ccagttcctt
    46621 attactcttt tattctgtca atcttctata tttcgagcaa ttccgccgag atatcttgat
    46681 taaacgaatt tcaggtttac gattttttga aacacatgct cagtatatgg ttagccaatt
    46741 tgccagtttt gtatttggtg ctagtttctt tattttaagc agtcgagact tggtgattgg
    46801 cttgctcact ttattcgtct ttctagctag tgcagttctg acgctttacc gtcaagcaca
    46861 gaaagaatct cgtgtttcta tgacaattat gaaaggaaaa taggatgatt gaactaaaga
    46921 atatatctaa aaaatttgga agccgtcagc tattttcaga tacaaatctt cattttgaag
    46981 gtgggaaaat ttatgcctta atcggtacaa gtggctgtgg taagacaaca ctcttgaata
    47041 tgattggacg attagagcca tatgacaaag ggcaaatcat ctatgatggc acttctctta
    47101 aggacatcaa gtcttctgtt ttctttagag attacttggg atacttattt caagattttg
    47161 gcttaattga aagccaaacc gtcaaagaga atctcaatct gggtttagtt ggtaaaaagt
    47221 tgaaggaaaa agagaaaatc tctttgatga aacaagctct aaaccgtgta aacctctctt
    47281 atttggattt gaagcaacct atatttgagt tatcaggagg agaagcacaa cgtgttgcat
    47341 tagcgaagat aattttaaag gatccgcctt tgattcttgc agatgaacca accgcttcct
    47401 tagaccccaa aaactctgag gaattacttt ccatcctaga atctttaaaa aatccgaatc
    47461 ggaccattat tattgcgacc cacaatcctc tgatttggga gcaagtggat caggtcattc
    47521 gagttaccga tttatcacat agatgatatg gtaagattca gttagaagaa agagtcacaa
    47581 acacactttg tggctttttt atttccataa aaatggtaaa atagtaggag tagaaatgga
    47641 gttcgagaca tgaaagtaat agatcaattt aaaaataaga aagtccttgt tttaggtttg
    47701 gccaagtctg gtgaatctgc agctcgtttg ttggacaagc taggtgccat tgtgacagta
    47761 aatgatggga aacctttcga ggacaatcca gctgcccaaa gtttgctgga agaagggatc
    47821 aaggtcatta caggtggcca tcctttggaa ctcttggatg aagagtttgc ccttatggtg
    47881 aaaaatccag gtatccccta caacaatccc atgattgaaa aggctttggc caagggaatt
    47941 ccagtcttga ctgaggtgga attggcttat ttgatttcag aagcaccgat tattggtatc
    48001 acaggatcga acggtaagac aaccacaacg actatgattg gggaagtttt gactgctgct
    48061 gggcaacatg gtcttttatc agggaatatc ggctatccag ctagtcaagt ggcccaaact
    48121 gcgtcggaca aggacacgct tgttatggaa ctttcttctt tccaactcat gggtgttcaa
    48181 gaatttcatc cagagattgc ggttattacc aacctcatgc caactcatat cgactaccat
    48241 gggtcatttt cggaatatgt agcagccaag tggaatatcc agaacaagat gacagcagct
    48301 gatttccttg tcttgaactt taatcaagac ttggcaaaag acttgacttc caagacagaa
    48361 gccactgttg taccattttc aacacttgaa aaggttgatg gagcttatct ggaagatggt
    48421 caactctact tccgtggtga agtagtcatg gcagcgaatg aaatcggtgt tccaggtagc
    48481 cacaatgtgg aaaatgccct tgcgactatt gctgtagcca agcttcgtgg tgtggacaat
    48541 caaaccatca aggaaactct ttcagccttc ggtggtgtca aacaccgtct ccagtttgtg
    48601 gatgacatca agggtgttaa attctataac gacagtaaat caactaatat cttggctact
    48661 caaaaagcct tgtcaggatt tgacaacagc aaggtcgtct tgattgcagg tggtttggac
    48721 cgtggcaatg agtttgacga attggtgcca gacattcctg gactcaagaa gatggtcatc
    48781 ctgggtcaat ctgcagaacg tgtcaaacgg gcagcagaca aggctggtgt cgcttatgtg
    48841 gaggcgacag atattgcaga tgcgacccgc aaggcctatg agcttgcgac tcaaggagat
    48901 gtggttcttc ttagtcctgc caatgccagc tgggatatgt atgctaactt tgaagtacgt
    48961 ggcgacctct ttatcgacac agtagcggag ttaaaagaat aaaatatgaa aaaaattgtc
    49021 tttacaggtg gggggacggt tggacacgtt accctcaatc ttttgttaat gcccaagttc
    49081 atcgaagatg gttgggaagt ccactatatc ggggacaagc gtggtatcga acaccaagaa
    49141 atccttaagt caggtttgga tgtcactttc cactccattg cgactggaaa attgcgtcgc
    49201 tatttctctt ggcaaaatat gctggacgtc ttcaaagttt gctggggaat cgtccaatcg
    49261 ctctttatca tgttgcgact tcgtccacag accctttttt caaagggggg ctttgtctca
    49321 gtaccgcctg ttatcgctgc gcgtgtgtca ggagtgcctg tctttattca cgaatctgac
    49381 ctgtctatgg gcttggccaa taaaatcgcc tataaatttg cgactaagat gtattcaacc
    49441 tttgagcaag cttcgagttt gtctaaggtt gagcatgtgg gagcagtgac caaggtttca
    49501 gatcaaaaaa atccagaacc agatgaattg gtggatattc aaagccactt taatcataaa
    49561 ttgccgactg tattgtttgt tggcggttct gcaggtgctc gtgtctttaa ccaattggtg
    49621 acagaccata agaaagaact aacagagcgc tacaatatta tcaatctaac tggagattct
    49681 agcctgaatg agttgagcca aaatcttttt cgtgttgact atgtgaccga tctctatcaa
    49741 cccttgatgg aattggctga tattgttgtg acacgaggtg gtgccaatac gatttttgag
    49801 ctcttggcga tagcaaaatt gcatgtcatt gtgccgcttg gtcgtgaagc tagtcgtggt
    49861 gaccagcttg aaaatgcagc ttactttgta aaaaaaggct atgcagaaga ccttcaagaa
    49921 agcgatttga ccttggatag tttggaagag aagctttctc acttactaag tcacaaggaa
    49981 gattaccaag ctaagatgaa ggcttctaag gaattgaaat ctctagcaga tttttatcaa
    50041 ttgttgaaaa aagatttatc ataaggaaag taaatgtcaa aagataagaa aaatgaggac
    50101 aaagaaatcc tcgaagaatt gaaagagtta tcagaatggc agaaacgaaa ccaagaatat
    50161 ctaaaaaaga aggctgaaga agaggcggct ctagctgagg agaaggaaaa ggaaagacaa
    50221 gctcgaatgg gagaagaatc tgagaagtca gaggacaaac aggaccagga gagtgaaaca
    50281 gaccaggaag attcagaatc agctaaggaa gagtctgaag aaaaagtagc atcctcagag
    50341 gctgacaaag agaaagaaga gaaagaagaa ccagagtcta aagagaagga ggaacaggat
    50401 aaaaagcttt ctaaaaaggc tacaaaggaa aaaccagcca aagcaaagat tcctggtatc
    50461 catatcttgc gagcattcac gattttattt ccaagtctgc ttttattgat tgtctctgcc
    50521 tacttgctca gtccttatgc gaccatgaaa gatattcgtg ttgagggaac ggtgcaaact
    50581 acagctgatg atattcgaca ggcttcaggc attcaggatt cggattatac gattaacctt
    50641 ctgctagaca aggcaaaata tgaaaagcag attaagtcta actattgggt tgaatcagct
    50701 caacttgtct atcaatttcc aactaagttc actattaagg tcaaggaata tgatattgtg
    50761 gcctactata tttctggtga aaatcattat cctattcttt ccagtggtca gcttgagact
    50821 agttctgtga gtctgaacag tttaccagaa acttatttat cagttctctt taatgatagt
    50881 gaacaaatca aggtttttgt ctcagaactt gctcaaatta gcccagaact caaggcggct
    50941 atccaaaagg tggaattagc cccaagcaag gtgacatccg atttaattcg attgaccatg
    51001 aatgattcgg acgaagtctt ggttcctcta tctgaaatga gtaagaaact gccatattat
    51061 agtaagatta agccacaatt gtcagaaccg agtgtggtcg acatggaagc tggaatttac
    51121 agttacactg tggcggataa attaattatg gaggctgagg aaaaagccaa acaagaggcc
    51181 aaggaagccg agaaaaaaca ggaagaagaa cagaaacgtt tagaagaaga acagaaaaaa
    51241 caagaggaag agagcaatcg aaatcaaaca aatcagcgtt catcgcgtcg ctaggtttac
    51301 cttttctctt atagttcttt agtgaccatg tttttacttg acaagtgcta gtagaaataa
    51361 tagaataata gaaaaccttt aaagcagtcc agagaggcag ctaaggttag acggtgaaag
    51421 ggtggagact acccattttt cgtggaacct tgctgttggc aggttccttt tttcgtggct
    51481 tctgttggcc agactctctc actagtaaag gtaaaaggag aaacctatgc gagaacatcg
    51541 tccaatcatt gctcttgatt ttcctagttt tgaggcggtc aaggaatttt tagctctttt
    51601 cccagcagaa gaaagccttt atctcaaggt agggatggag ctttattacg cagcggggcc
    51661 tgagattgtg tcctacttaa aaggtttggg tcatagtgtc tttttggatc tcaaacttca
    51721 tgacattcct aatacagtca agtcagtcat gaagatccta tctcagcttg gtgtggatat
    51781 gaccaatgtt catgcggctg gtggtgtaga gatgatgaag gctgcgcgtg aaggtcttgg
    51841 aagtcaagct aaattgatcg ctgtaactca gctcacatca acgtcagaag ctcagatgca
    51901 ggagtttcaa aatatccaaa ccagtctgca agagtctgtg attcactatg ccaagaagac
    51961 agctgaagct ggcttggatg gtgttgtttg ctcggctcag gaagtacaag tcatcaagca
    52021 ggctaccaat ccagatttta tctgtctgac accagggatt cgtccagctg gtgttgcagt
    52081 tggagatcaa aaacgagtca tgacacctgc tgatgcctat caaatcggca gtgactatat
    52141 cgtagtggga cgtcccatta cccaagctga ggatcctgtt gcagcttatc atgccatcaa
    52201 ggatgaatgg acacaggact ggaattaaag aactagatta gaaaaataaa aggagaatac
    52261 catgacactt gctaaagata tcgctagcca cctcttgaaa atccaagccg tttacctcaa
    52321 accagaggaa cccttcactt gggcatctgg tatcaagtca ccgatttaca ctgataatcg
    52381 tgtgacacta gcctatccag aaactcgtac cctaattgaa aatggttttg tggaagctat
    52441 caaagaagcc tttcctgaag tagaagtgat tgcaggaact gcaacagcag ggattccaca
    52501 cggagccatt attgctgata agatggactt gccttttgcc tacatccgta gcaaaccaaa
    52561 agaccacgga gctggtaatc aaatcgaagg tcgcgtagct caaggtcaaa aaatggtagt
    52621 ggttgaagac cttatttcaa cgggtggttc agttcttgaa gctgtagcag cagccaagcg
    52681 agaaggagca gatgtacttg gagttgtagc gattttcagc taccaattgc caaaagcaga
    52741 taagaacttt gcagatgctg gtgttaaact tgtgacgctt tcaaactata gcgagcttat
    52801 ccatctagcc caagaagaag gttacatcac gccagagggc cttgatcttc taaaacgctt
    52861 taaagaagac caagaaaatt ggcaagaagg ttaggtcagt aagataaaga gagacgaggc
    52921 taccgagtct cttttaccat tttatttaaa atatgacaat attttaaata aaataattga
    52981 caacgctttc ttttattgat ataatgaaaa tgtaatatgt atcaaattga tcaatcaact
    53041 atcttgttta tcacttctta agaggacgat gtcatgaaaa gaagaaaaat atattccttt
    53101 tttgcgtagt tacaattgca tctagtttgt ttctccctac agttttagct agacagattg
    53161 gaaattatga tttaacgttg ccgcgttggg gttcggatac aactagtgag cttgagaaag
    53221 aaaacgcctc tgctggaatt aataatagtg acagcactgg tggcggtaaa aggttaaata
    53281 cctctattcg tagcgcctat agtgggtcag atattacccc ggtatattca ttggggtctg
    53341 gctctaggat tgtcatgtac tataatggag gtggtgacaa ttatattggt tctggtacta
    53401 gattagctat ggcgccacaa tttggaaatc atgtaagaat tcatacttca ggttcttgga
    53461 gtccagattc ttattaactt acttgtcaga gtaagcctta aagatggttg attgtgggtg
    53521 tagcatgaaa aaagaatgct acaccctatt tttattataa ggaggagtaa ggatggaatt
    53581 tttcatttgt aatcttgtac gagtcgttca atcacctcgg ttttatatgt ctttattttt
    53641 gacccttctt tgcatgagtt taggaaattt tcttgctttc aatggtattt ataaaattga
    53701 aggtttatcg attttttttg ccgcttcttc tattcgagga ttttcaccga ttagcctagt
    53761 agctgcactt atctgtacac tgccctattc tagtcagata atagaggatg ctgagagtca
    53821 ttttctaaca gcacaattgt gccgaatttc taaaaagagg tatctagcta ttgtaggtag
    53881 tactgcaatt atttcttctt ttctagtctt ttttctcccc tatttattat tattaggaat
    53941 taatctttta gtgactcctt atcaggaaat ttatattgga gattatagtg gtgccttaaa
    54001 agaattattt gattctaatc agtttctcta tagtcttgtg acgactctct ggtatggagt
    54061 ttggggcgct gtgttctcta tttttggact agctagtgct ttgctagtga agaaaaaatt
    54121 aggagctatt ttcatcccag ttgcctatat gatggttggt ggtattttat gggctatttt
    54181 agggctatct tacttagaac ctgtgacaac gctagctttg ggatatcaga aagatatcag
    54241 tctttcctta gttagtgggc atcttgcttt tattttattt gttagttgtt tggttgttta
    54301 tggtacattt tttctacatt cagaggacta tgtataatga aacaatttgt tcaattttat
    54361 aaaaaagatt tcttagcagt attggtttat tttatattac tgctatcctg tgttttatct
    54421 agtacagtat atttattgcg ctgtcgccaa tattcaatcc atccaaatgt attagaatgg
    54481 atcttagttt tacttcaaga tatgacgact ggagtatatt gctttccgtt cacatatata
    54541 ttgttctttt tttatttgat gaataactat tttaataggt tggagtgtcg cattcgtctg
    54601 aaatcaatta agcactttac cagttttagt ttcaaattag cagctcttag tacggggatt
    54661 tggacggcga ttttattttt attgattttt ctaattgcat ttagtaatgg ttttagcttc
    54721 tctttggaga taaaggaggt tgatttttta agagaatttt atggcataag tattgcaaac
    54781 aatgctagtt tctttatagg attttttttc tcttatatag catactattt ctttttatcc
    54841 ttacttacta ttagcagttt ttcttggttt aaaaaatcaa acatgagctt agtatttctg
    54901 tttacttttt tatttgtaga atccttattc tggatttatc agttgaacaa tgggataatt
    54961 ggattattgc caatttttca gtatatggta aattccaatc cgtatgcatt gatttattgg
    55021 cttgcattac tatctatcat aattccattg actgtatttt ctgttcatag aaactggagg
    55081 agagtgtaaa agttggaaat gggaaagtta agtagtcaca tatggaggtt gaatcagata
    55141 atctatacca agtacttttg gggttatgtt cttttttgga tattgatttg tttaggatta
    55201 tggtattggt tagaaggaaa tgatagactt gttatagaaa ttttaaaagg gcctaatctg
    55261 agtcaaaact cttttttagt cttatctata tggttgcttc attggtttat tattcataca
    55321 ttttttctag cagttgtata tcgtagaaga gcatccgatt tctttatgga agtgattcga
    55381 ttttcttcta ttaagctctg gattaggtat cagatttgga cctgttttct ttatggactc
    55441 attttaatca tggtaaaagt tctagtgatt caatttatgt tacagttagc aaactgggat
    55501 ataggagttt tgtttatagt tgattctttg aatgcttgtg tgctatcctt gctttgcttt
    55561 atgttatacg cactaggagc gaatgtacaa atgaactttg cttgcgttag tttcttttta
    55621 ctcatgattg tgtttggtgg tctatttgta ggaaatcgaa ctaattatct attttatatt
    55681 ttgaatcgag ggaatggaga tataggacga gatttatttc ttcagttgct atttttagtc
    55741 tttcttttta aaagcatttt ctatttcact cgtcaaaaga ggaggtttat agaatgaatg
    55801 aaataattac attaaaaaat attgagttga aattaaaaaa aacatgtgtt tttcaaaacc
    55861 ttaattttag ttgtaaacag ggggaaatta taggaattac tggtgcgaat ggctcaggta
    55921 aaagtgtatt gtttaaatta atagctggtt tatatagtcc gtcttatgga gaagtgttaa
    55981 tcaatgggga aaatattgtt cctgagagaa aaattccagc taatttggga gctttgattg
    56041 aagaacctgg ttttataaat tattatagtg gctttaagaa tttacaatat ttggcaagca
    56101 tacgaggagt agttggtaat caggaaatca atgatacact gaaaatagtt ggtctatatg
    56161 agcaaaaaga ccagaaagtt aaaacttatt cgctaggtat gaggaaaaag ctagggattg
    56221 ctcaagcaat tatggagaat ccctctattc ttttactaga tgaacctatg aatgccttgg
    56281 ataaatcaag tgtagaaaat atgagaacat tgtttagaaa gctctctagt gaaaaaggga
    56341 caacaatttt gattgctagt catagtgaag aggatattcg tatcttatgt gataaagtat
    56401 atgcaataga agataaagta tgtacactgt gttcagattg aacatcttag atagactcag
    56461 gatgttatag gtaaaatctt aaaaagggat tggagcttaa aatccagtcc cttttaagag
    56521 ttaatggcca ccttcaacaa ccaggtcatc tgctttagca gcgtcaccgt aggttgggtg
    56581 aagtgttttt tcataggcct tgtggaagaa gttttccttg cctaattttt caatatcttt
    56641 attgatgaag tctagcaatt cttggttgcc tttttgaact gctgccgcaa tggtatcggg
    56701 atcaccgagg gaagtaattc ctacttcaaa tcctttattt tcaagtgccc aagctagaac
    56761 ttccgtattg tcagttgaaa aggcatctcc acgtccgtca agaagagctt ggtaagagtc
    56821 actgtattgg tcgtattttt ggagtttgat ttctggatga ttcttttcaa aataagtctc
    56881 agcagtcgtt ccttttgtga caattaaggt tttaccttca agttgtttga cgtctgtaat
    56941 gagaccagtc ttaggtgata cgacacccag agaaactttc atatatggaa gggcaaaatc
    57001 aacttgtttc ttacgttcgt cagttactgt aaagttagca agagtaatat ctaccttgtt
    57061 tgaaatcaag tattccgcac ggttggcagc atcgactgaa atgtatttaa ccttgacacc
    57121 aaggtcttga gctagttggt tccctagttc aatatcgtag cgtagccttg gtaagaacca
    57181 tcattgtcaa cgtagccaaa cggtttttta tctccaaaca cggcgattcg cagttcaccg
    57241 ctttttttga tttcatcgat agtgcgagct ttggcagttg tttttccaga ggatgaacca
    57301 gcgtttccac ctgagctaca agcagtgata aagataaggg caaaggcaag tgctaaaaca
    57361 gttaagagtg gtttgaatag tttcataaga atctccttta tagatatgag ccgaattggc
    57421 taaagtcaaa gacgtttaaa aattcctggg ctcgtttggt ttgcggattg gtaaagaagg
    57481 cttgagctgt tccttcttca gcgattttcc cttggtcgag gaagataatc cggtcagtaa
    57541 tggcttgggc aaactgcatt tcgtgggtta ctaaaatcat ggtacggcct tcttgggcca
    57601 aatcattgat aagttccagc acctcacgca ccatttctgg atccagcgaa gcagtcacct
    57661 cgtcaaaaag gatgatttct ggatgcatta ggagggcacg ggcaattgca acacgttgct
    57721 tctgtccacc agataattga cgggcaaagc aaagctatgt tgtttatcca gcaaatcgac
    57781 acgatctagt aattgcaaag cttcttccgt tacttctttc ttgtcccttc cttgagcttt
    57841 gatagggcct aggatgaggt tttgtaagac atccagatgg ggaaagagtt cataactttg
    57901 aaagaccatg ccaatctttt ggcgaactag gtgaaaatct tttttatttt caacgataga
    57961 ctgaccatcc agaagaatat ctccaccttg aatactttct aagccgttga ggcaacgaag
    58021 gagggtactt ttcccacaac cagatgcccc taggatgaca acaacttccc ccttttttga
    58081 tttctagaga aagtccttgg aggatgggat tgtctccgaa ggattttttt agttccttga
    58141 tttctaagat agtttcagac atttagtttc tccaatgttt ttctaagtga gtggatagtt
    58201 tggaaatagg gtagcaaact gcgaaatata agactagaat ggttccataa atccaaaatg
    58261 aagcagttgg gatggtcagg cgattgctat cgatgatttg ttgtccaact ttggtcactt
    58321 ccacaacccc aatcaaaaca actaatgaag tggttttaat catccgagtg acaagattga
    58381 tagcctgcgg tagcagtctt cttaagactt gtgggatgat gatgtggtag taaagttgaa
    58441 cattagtcaa gtcgagtgcc tatccacttt caaactgatg tttagggaga gaagtgatag
    58501 ctccacgtac caagtctccc atttcagctg ttccccagag ggtaaaaatg ataatagctg
    58561 aagtctcacc tgagatattg atattaaagt ttcgagccaa gccaaagtaa acgatgaaga
    58621 gtagcaccag ctggggcatg atacggataa attccagata caatcgtgtt aaaaatcgta
    58681 tgattctaga atgggaggtc atgatgattc ccatgactgt tccgaacatc atggataaga
    58741 ggacagacag gatggatatc ccaatcgtaa cgcccaaccc ctgtaagatt ctcaggagat
    58801 tatttccttg aaagagtact tggattcccg aatcctgcat ggcgggtcct cctttctatc
    58861 cagctaaaga ccagtgagat gggtagcagc atgatcagat aagcaactac caacatagct
    58921 agcgcaatgt ctgtctcata gtagagacca atcaaatcct tggcgacgta catgaggtcg
    58981 gccaaagcca ctgctgagaa aacagaggtt tccttgataa ggaaaatgac attggcacta
    59041 aaggagggga gtgccaccgc tgttgcttgc ggaagaacca catagcgaaa gacctgtaga
    59101 ggtgtcagac caatagcgag gccaatctcc tgctgggttt gactgatggc ttccagccca
    59161 cttcggaaag attctgccat ataggagcct cctaaaaaga caaggccaag cgttgcacag
    59221 acttctgaag ataggacaat cccgattcgg ggaagaccga agtagagaaa gaagagttga
    59281 atcaaaaggg gcgtattacg tgacaattca atgtaggctg tcgctacttg cgccaaaaca
    59341 gggattcgat aatgtcggat gatactaacg attaaaccga gcagaaagga tcccaaaatt
    59401 ccccaaactg caatatgcaa ggtcagaaag aatgcctttt gatatagtgg tagatattgt
    59461 tcaacaatgg accaatccaa aaatagaacc tcccatctag aaataataca gttattgtag
    59521 cacttaaaat cttctttgga taatatctat tttttattgc cgttataagg attttttacc
    59581 atagacataa aatttctgaa atttccaaac aaaatatttg aaaagttttg aaaaagagtt
    59641 aagatatttt tgtaatatac aaagtgaacg cttacttat
//
LOCUS       DAVKZI010000008        56081 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKZI010000008 DAVKZI010000000
VERSION     DAVKZI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.008"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            402..1262
                     /gene="speE"
                     /locus_tag="VXB18_000580"
     CDS             402..1262
                     /gene="speE"
                     /locus_tag="VXB18_000580"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0381825.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            1259..2518
                     /locus_tag="VXB18_000581"
     CDS             1259..2518
                     /locus_tag="VXB18_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0381826.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            2518..3645
                     /gene="nspC"
                     /locus_tag="VXB18_000582"
     CDS             2518..3645
                     /gene="nspC"
                     /locus_tag="VXB18_000582"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0381827.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            3642..4727
                     /gene="aguA"
                     /locus_tag="VXB18_000583"
     CDS             3642..4727
                     /gene="aguA"
                     /locus_tag="VXB18_000583"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0381828.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            4737..5612
                     /gene="aguB"
                     /locus_tag="VXB18_000584"
     CDS             4737..5612
                     /gene="aguB"
                     /locus_tag="VXB18_000584"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0381829.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(5793..6602)
                     /locus_tag="VXB18_000585"
     CDS             complement(5793..6602)
                     /locus_tag="VXB18_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0381830.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            6874..7095
                     /locus_tag="VXB18_000586"
     CDS             6874..7095
                     /locus_tag="VXB18_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0381831.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            7149..7820
                     /locus_tag="VXB18_000587"
     CDS             7149..7820
                     /locus_tag="VXB18_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0381832.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASRGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(7872..8069)
                     /locus_tag="VXB18_000588"
     CDS             complement(7872..8069)
                     /locus_tag="VXB18_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0381833.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            8062..8970
                     /locus_tag="VXB18_000589"
     CDS             8062..8970
                     /locus_tag="VXB18_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0381834.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            8967..9428
                     /locus_tag="VXB18_000590"
     CDS             8967..9428
                     /locus_tag="VXB18_000590"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0381835.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            9418..10305
                     /locus_tag="VXB18_000591"
     CDS             9418..10305
                     /locus_tag="VXB18_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0381836.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEYVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            10308..12191
                     /gene="cbpE"
                     /locus_tag="VXB18_000592"
                     /gene_synonym="pce"
     CDS             10308..12191
                     /gene="cbpE"
                     /locus_tag="VXB18_000592"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0381837.1"
                     /translation="MKKKLTSLALVGAFLDLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQADWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            12271..13401
                     /locus_tag="VXB18_000593"
     CDS             12271..13401
                     /locus_tag="VXB18_000593"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0381838.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEVEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            13411..14673
                     /locus_tag="VXB18_000594"
     CDS             13411..14673
                     /locus_tag="VXB18_000594"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0381839.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            14677..15474
                     /gene="proC"
                     /locus_tag="VXB18_000595"
     CDS             14677..15474
                     /gene="proC"
                     /locus_tag="VXB18_000595"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0381840.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     SSLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            15694..16332
                     /locus_tag="VXB18_000596"
     CDS             15694..16332
                     /locus_tag="VXB18_000596"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0381841.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            16329..17219
                     /locus_tag="VXB18_000597"
     CDS             16329..17219
                     /locus_tag="VXB18_000597"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0381842.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFESLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            17259..17576
                     /gene="yabA"
                     /locus_tag="VXB18_000598"
     CDS             17259..17576
                     /gene="yabA"
                     /locus_tag="VXB18_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0381843.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            17579..18448
                     /gene="rsmI"
                     /locus_tag="VXB18_000599"
     CDS             17579..18448
                     /gene="rsmI"
                     /locus_tag="VXB18_000599"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0381844.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            18675..19193
                     /locus_tag="VXB18_000600"
     CDS             18675..19193
                     /locus_tag="VXB18_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0381845.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            19302..19946
                     /locus_tag="VXB18_000601"
     CDS             19302..19946
                     /locus_tag="VXB18_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV0381846.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVRL
                     GLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYIE
                     NNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(19935..20739)
                     /locus_tag="VXB18_000602"
                     /pseudo
     CDS             complement(19935..20739)
                     /locus_tag="VXB18_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            20749..20989
                     /locus_tag="VXB18_000603"
                     /pseudo
     CDS             20749..20989
                     /locus_tag="VXB18_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
     gene            21234..22568
                     /gene="trmFO"
                     /locus_tag="VXB18_000604"
     CDS             21234..22568
                     /gene="trmFO"
                     /locus_tag="VXB18_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0381847.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            22652..23389
                     /locus_tag="VXB18_000605"
     CDS             22652..23389
                     /locus_tag="VXB18_000605"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0381848.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            23398..23955
                     /gene="frr"
                     /locus_tag="VXB18_000606"
     CDS             23398..23955
                     /gene="frr"
                     /locus_tag="VXB18_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0381849.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            24015..24869
                     /gene="cvfB"
                     /locus_tag="VXB18_000607"
     CDS             24015..24869
                     /gene="cvfB"
                     /locus_tag="VXB18_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0381850.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            24878..25093
                     /locus_tag="VXB18_000608"
     CDS             24878..25093
                     /locus_tag="VXB18_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0381851.1"
                     /translation="MRKSFYIWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            25179..26147
                     /locus_tag="VXB18_000609"
     CDS             25179..26147
                     /locus_tag="VXB18_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0381852.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(26125..26304)
                     /locus_tag="VXB18_000610"
     CDS             complement(26125..26304)
                     /locus_tag="VXB18_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381853.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            26340..26840
                     /locus_tag="VXB18_000611"
     CDS             26340..26840
                     /locus_tag="VXB18_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381854.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            26843..27102
                     /locus_tag="VXB18_000612"
                     /pseudo
     CDS             26843..27102
                     /locus_tag="VXB18_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(27469..27795)
                     /locus_tag="VXB18_000613"
     CDS             complement(27469..27795)
                     /locus_tag="VXB18_000613"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381855.1"
                     /translation="MVDLAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(27741..28154)
                     /locus_tag="VXB18_000614"
                     /pseudo
     CDS             complement(27741..28154)
                     /locus_tag="VXB18_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810031.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28155..28580)
                     /locus_tag="VXB18_000615"
     CDS             complement(28155..28580)
                     /locus_tag="VXB18_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0381856.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYFRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVADRMAV"
     gene            28757..29326
                     /locus_tag="VXB18_000616"
     CDS             28757..29326
                     /locus_tag="VXB18_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381857.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            29394..30044
                     /locus_tag="VXB18_000617"
     CDS             29394..30044
                     /locus_tag="VXB18_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0381858.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            30028..32268
                     /locus_tag="VXB18_000618"
     CDS             30028..32268
                     /locus_tag="VXB18_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0381859.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGEKLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTIKEGKGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKGSLKQKQFVVELQATKTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            32667..33254
                     /locus_tag="VXB18_000619"
     CDS             32667..33254
                     /locus_tag="VXB18_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0381860.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            33258..34433
                     /locus_tag="VXB18_000620"
     CDS             33258..34433
                     /locus_tag="VXB18_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381861.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEAKLSQMSDTSSEEYQFAKSNLELQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIIWILEAIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAMSS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVKQEVTIGKMQDVLFPS
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    34607..34738
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            34754..35284
                     /gene="infC"
                     /locus_tag="VXB18_000621"
     CDS             34754..35284
                     /gene="infC"
                     /locus_tag="VXB18_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0381862.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            35317..35517
                     /gene="rpmI"
                     /locus_tag="VXB18_000622"
     CDS             35317..35517
                     /gene="rpmI"
                     /locus_tag="VXB18_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0381863.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            35569..35928
                     /gene="rplT"
                     /locus_tag="VXB18_000623"
     CDS             35569..35928
                     /gene="rplT"
                     /locus_tag="VXB18_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0381864.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            35986..36366
                     /locus_tag="VXB18_000624"
     CDS             35986..36366
                     /locus_tag="VXB18_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0381865.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            36616..37416
                     /locus_tag="VXB18_000625"
     CDS             36616..37416
                     /locus_tag="VXB18_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0381866.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGHVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPENETVSQRVCEDGPVFRTGTVVL"
     gene            37427..38365
                     /locus_tag="VXB18_000626"
     CDS             37427..38365
                     /locus_tag="VXB18_000626"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0381867.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSTEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            38407..40572
                     /gene="lytB"
                     /locus_tag="VXB18_000627"
     CDS             38407..40572
                     /gene="lytB"
                     /locus_tag="VXB18_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0381868.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(40633..42288)
                     /gene="pavA"
                     /locus_tag="VXB18_000628"
     CDS             complement(40633..42288)
                     /gene="pavA"
                     /locus_tag="VXB18_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0381869.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSIFQGLGRDTANELERILVSEK
                     FSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLETDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            42393..42890
                     /gene="ybeY"
                     /locus_tag="VXB18_000629"
     CDS             42393..42890
                     /gene="ybeY"
                     /locus_tag="VXB18_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0381870.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            42871..43266
                     /locus_tag="VXB18_000630"
     CDS             42871..43266
                     /locus_tag="VXB18_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0381871.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            43283..44182
                     /gene="era"
                     /locus_tag="VXB18_000631"
     CDS             43283..44182
                     /gene="era"
                     /locus_tag="VXB18_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0381872.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            44231..45055
                     /gene="mutM"
                     /locus_tag="VXB18_000632"
     CDS             44231..45055
                     /gene="mutM"
                     /locus_tag="VXB18_000632"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0381873.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            45055..45660
                     /locus_tag="VXB18_000633"
     CDS             45055..45660
                     /locus_tag="VXB18_000633"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0381874.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            45647..46846
                     /locus_tag="VXB18_000634"
     CDS             45647..46846
                     /locus_tag="VXB18_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0381875.1"
                     /translation="MTEINWKDNLRIAWFDNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            46846..46995
                     /gene="rpmG"
                     /locus_tag="VXB18_000635"
     CDS             46846..46995
                     /gene="rpmG"
                     /locus_tag="VXB18_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0381876.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            47035..47268
                     /gene="secG"
                     /locus_tag="VXB18_000636"
     CDS             47035..47268
                     /gene="secG"
                     /locus_tag="VXB18_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0381877.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            47370..49724
                     /gene="rnr"
                     /locus_tag="VXB18_000637"
     CDS             47370..49724
                     /gene="rnr"
                     /locus_tag="VXB18_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0381878.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKYSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTQ"
     gene            49687..50154
                     /gene="smpB"
                     /locus_tag="VXB18_000638"
     CDS             49687..50154
                     /gene="smpB"
                     /locus_tag="VXB18_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0381879.1"
                     /translation="MAKGEGKVVAHNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            50170..51030
                     /gene="tehB"
                     /locus_tag="VXB18_000639"
     CDS             50170..51030
                     /gene="tehB"
                     /locus_tag="VXB18_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0381880.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            51103..52056
                     /gene="coiA"
                     /locus_tag="VXB18_000640"
     CDS             51103..52056
                     /gene="coiA"
                     /locus_tag="VXB18_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0381881.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            52075..53877
                     /gene="pepF"
                     /locus_tag="VXB18_000641"
     CDS             52075..53877
                     /gene="pepF"
                     /locus_tag="VXB18_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0381882.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLIHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            53879..54592
                     /locus_tag="VXB18_000642"
     CDS             53879..54592
                     /locus_tag="VXB18_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0381883.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            54659..55600
                     /gene="prsA"
                     /locus_tag="VXB18_000643"
     CDS             54659..55600
                     /gene="prsA"
                     /locus_tag="VXB18_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0381884.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(55717..56058)
                     /locus_tag="VXB18_000644"
                     /pseudo
     CDS             complement(55717..56058)
                     /locus_tag="VXB18_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        16879 a        10271 c        12693 g        16238 t
ORIGIN      
        1 gttgagctgt cgaaaagaca gatctaagag ttcaaaacca gctttattat ttgaaaaagt
       61 gagtggttta agaacagttt tcctcgaaca ttcaaggctg taacatcgtg tttattttta
      121 gcgacatcaa tacctacata aagcatggga gtacctccag atatagtatt tcaagtctac
      181 ttggttatcc acgaactttt tgccttgtta ccttagacga gataaaacgt ctatgcgtta
      241 tcaaactcat taccaattga aacaaaaagc tgtggttaga gcctttcgga aatcgttaag
      301 cgattggagg aaatgaacta atccacagtg acttattcca agtataccac ttgggctttg
      361 gcagtagcta actgcgctaa atataatata aggagaaata gatggattta tggttttctg
      421 aagttcatac tccagatgtc aaattgtctc tgagaacagc caagcaactt tacgctggaa
      481 aaagtgaatg gcaggatatc gaagtcttgg atacgccagc ttttgggaaa atactgattt
      541 taaatggcca tgtcttgttc tcagatgcgg atgatttcgt ctacaatgaa atgaccgtcc
      601 acgttcccat ggctgtccac ccaaatccaa agaaagtatt ggttattggg ggtggtgacg
      661 gcggtgttgc ccaagtatta acactctatc ctgaactgga acaaatcgat atcgtggaac
      721 cggatgagat gttggtcgag gtctgtcgtg agtatttccc agactttgct gcagggctag
      781 atgatcctcg tgttaccatt tactaccaaa atgggctacg ctttttgcga aactgcgaag
      841 atgattacga tattatcatc aacgatgcga cagatccatt tggccatacg gaaggactct
      901 ttaccaagga attctacggc aatagttatc gagctctgaa ggaagacggc atcatgattt
      961 accagcatgg gagtcccttc tttgacgagg atgagtcggc ctgccgaagc atgcaccgca
     1021 aggtcaatca agcctttcca atcagtcggg tttatcaggc ccatattcca actagcccag
     1081 ctggctattg gttgtttgga tttgcatcga aaaaatacca ccctgtcaaa gattttgaca
     1141 aggaaggctg gaaaaaacgc cagcttttca cagaatacta cactgcaaac ttacacgtgg
     1201 gagcctttat gttgcccaag tatgttgagg acattttaga agaagaggaa ggaaaaaaat
     1261 gagtcgttta ctagttattg gttgtggggg cgttgcccaa gttgctattt caaagatttg
     1321 tcaagatagc gaaacattta cagagattat gattgctagc cgtaccaagt caaaatgcga
     1381 tgacttgaaa gcgaagctag aaggcaaaac aagtactaaa attgaaactg cagcacttga
     1441 tgctgacaag gtagaagagg tcattacctt gattgaaagc tacaaaccag aagctgtttt
     1501 gaatgtagct ctgccttatc aagatttaac cattatggat gcttgtttgg caacaggtgt
     1561 tcactatatc gatacagcca actacgaagc agaagacaca gaagaccctg agtggcgtgc
     1621 tatctacgaa aaacgttgta aggaacttgg ttttacagcc tactttgact actcatggca
     1681 gtgggcttat caagagaaat tcaaagaagc aggcttgact gctcttcttg gttctggttt
     1741 tgacccaggt gtaaccagtg tcttttcagc ttatgccctc aaacactatt ttgatgaaat
     1801 ccattatatc gacattttag actgtaatgg cggtgaccac ggttatccat ttgcaaccaa
     1861 cttcaaccca gaaattaatc tccgtgaggt ttctgcgcca ggttcttact gggaagatgg
     1921 gaaatgggtc gaagtcgaag ctatgtctat caagcgtgag tatgatttcc ctcaagttgg
     1981 acaaaaagat atgtatctcc ttcaccatga agaaatcgaa tcattggcca agaacattcc
     2041 aggtgtcaaa cgcattcgtt tctttatgac ttttggtcaa tcttacttga cgcacatgaa
     2101 atgtcttgaa aatgttggac tccttcgtac ggataccatt aactttaacg gccaagaaat
     2161 tgttccaatt caatttttga aagccttgct tccagatcct gctagccttg gcccacgtac
     2221 tgtaggtaaa accaatattg gatgtatctt tacaggtgtc aaagatggcg ttgaaaagac
     2281 tatctacatc tacaatgttt gcgaccatca agagtgctat gcagaagtcg ggtcacaagc
     2341 aatttcatac acgacaggcg ttccagccat gattgggaca aaattagtca tgaacggaac
     2401 ttggaaacaa gctggagtgt ataaccttga ggagttagat ccagatccat tcatggaagc
     2461 tttgaatgag tatggtttgc catgggttgt ggttgaaaat ccacaaatgg tggactaatg
     2521 aagttagaac aagtaccaac accagcctat gttattgact tggccaagtt agaagctaat
     2581 tgccgcattc tacaatatgt acaagaagag gccggttgca aggtcttgct tgcccagaag
     2641 gcatattccc tctacaaaac ttatcccttg attagccagt atctatcagg tacgacagct
     2701 agtggactct atgaggccaa attggcaagg gaagaatttc ctggtgaagt ccatgttttt
     2761 gcaccagctt tcaaggatga ggacatggag gaattgcttg ggataacaga ccatatcgtc
     2821 tttaactcag agagacagtt gcgtaagcat ggggctcgtt gtcgagaggc tggtgtcagt
     2881 gttggtttgc gcctcaaccc tcagtgttca actcaaggag atcacgcgct ctatgaccct
     2941 tgtgcacctg gttctcgctt tggagttact atagacaaga ttccgagtga tttgctagat
     3001 ttggttgacg gacttcattt tcataccctt tgcgagcagg gagcagatga tttacaaaca
     3061 actttgaaag cagtagaaga acagtttggt ccctacttac atgaggtaaa atggctcaat
     3121 atgggtggtg gtcatcatat tacaagagaa ggttacgatg tggatttgct gatttcagaa
     3181 atcaagcgta tccgaaaaac ttacaatctt gaaatctata tcgagcctgg tgaagccatt
     3241 gcgcttaatg cgggttattt agcaactgag gtattagata ttgtagaaaa cggtatggaa
     3301 atcttggttt tagacgcctc tgcgacctgc catatgcctg atgtacttga gatgccctat
     3361 cgtccacctt tgagaaatgg ctttgagtca caggaaaaag cccataccta cagactttct
     3421 tctaatacct gtctgactgg cgatgtgatt ggtgattata gttttgaaaa tccagtccaa
     3481 atcggagaca gactttattt tcaagacatg gccatttatt cttttgtcaa aaataatacc
     3541 tttaatggta ttggattgcc aagtctctat ctcatggacg aacagggaga ctgtagctta
     3601 ctcaaagctt ttggctatca agactttaaa gggagattat catgatggac agtccaaaaa
     3661 aattaggcta tcacatgcca gcagagtacg aaccccatca tggtaccctc atgatatggc
     3721 cgactcgacc aggatcatgg ccttttcaag gaaaggctgc taaaagagca tttactcaga
     3781 tcatcgagac catagcagaa ggggaaagag tctatctttt ggtggagcag gcctatctat
     3841 ctgaagccca atcctatctt ggagacaagg ttgtttattt agacattccc accaatgatg
     3901 cctgggcgcg tgatactggc ccaaccattc tcgtcaatga taaaggtaag aaattagccg
     3961 tggattgggc ctttaatgct tggggaggca cctatgatgg tctttatcaa gattatgaag
     4021 aggatgacca agtagccagt cgttttgctg aggccttgga aaggcctgtc tatgatgcta
     4081 aaccttttgt actggaagga ggcgcaatcc atagcgatgg tcaaggaact attctcgtaa
     4141 ctgaaagttg cttgcttagt cctggtcgca atcctaactt gactaaagag gagattgaaa
     4201 acacattatt agaaagtctt ggtgctgaaa aagttatttg gcttccttat ggtatttatc
     4261 aggatgaaac caatgaacac gtcgataatg ttgttgcctt tgttggtcct gctgaggttg
     4321 ttttggcttg gacagatgac gaaaatgatc cccagtatgc catgtcaaaa gcagatctcg
     4381 aactcttaga acaggaaaca gatgcaaaag gttgtcactt caccattcat aaattgccta
     4441 tccctgcagt tcgacaagtt gtgacagaag aagatttgcc aggctacatc tatgaagaag
     4501 gagaagaaga gcgatacgca ggtgaacgac tagcagcttc ctacgtaaac ttttatatcg
     4561 ccaacaaggc tgtcttggtt ccacagtttg aggatgtaaa cgaccaagtg gccttagata
     4621 tcctcagcaa gtgtttccca gaccgtaaag ttgtcggaat accagccaga gatattctct
     4681 taggtggtgg caatatccac tgtatcaccc aacaaattcc agaataggag aaaaagatga
     4741 gaaatgtaag agttgcaacc attcagatgc aatgcgctaa ggatgtggca acaaatatcc
     4801 aaaccgcaga gcgtttagta cgtcaggctg ctgagcaagg agcccaaatt attctcttgc
     4861 ccgagttgtt tgaacatccc tatttctgtc aggaacgtca gtatgactac taccagtatg
     4921 cccaatctgt agcggaaaat actgccattc agcattttaa ggtgattgct aaggaactac
     4981 aagttgtttt accaatcagt ttctatgaaa aagatggtaa tgtcttgtat aactctattg
     5041 ccgtcattga tgcagatggg gaagtgctgg gcgtttatcg aaagacccat ataccagatg
     5101 accattatta tcaagaaaaa ttctatttca cgcctggtaa cactggtttc aaggtctgga
     5161 atactcgcta tgctaagatt ggtatcggta tctgttggga tcaatggttc cctgaaacag
     5221 cgcgctgtct tgcattgaat ggtgctgaat tgctctttta tcctacagct atcggttcag
     5281 agccaatttt ggatacagat agttgtggtc actggcaacg tactatgcaa gggcacgcag
     5341 cagcgaatat tgttccagtc atcgcagcca atcgttatgg tttagaggag gttactccta
     5401 gtgaggaaaa tggcggacag agttccagtc ttgacttcta cggttcctcc tttatgacgg
     5461 atgaaacagg agctattcta gaacgagctg aaagacaaga agaagctgtt ctgttagcta
     5521 cttataacct agacaaggga gcaagtgaac gcctaaactg gggcttgttt cgagatagaa
     5581 gaccagaaat gtatagacaa attacagatt agtgtgggag aaatgagaga ttcattctgc
     5641 tagactaact tcttattagc aactataaga tactatggca tctagtaaat cgatttttat
     5701 gattcgctat tcttctctat tgattagtcc gtattttaaa atattagcaa aaaagcaaat
     5761 agcagtaact tctgtctatt tgcttttctt ttttatagaa tatatttctc aatagcacgc
     5821 gcaacgccgt cttcttcgtt gcttgaggta acggcatccg caagagattt gacataatcg
     5881 ctggcatttc ccattgcaat cccaagccct gcaaactgga gcatttcgat atcgttatta
     5941 gcatcgccca tggccataat ctctgaggaa tcaatcttca aaatctcagc tagtcgtgaa
     6001 agagcagtag cctttgtcgt tccaagtggc attgcttcat aaatgacagg ctgcgaacga
     6061 actccactga atcgttggca aagctcttca gcaaaacgct gctcaaaatc gtctgtttgt
     6121 tcttttgttc ctaaaaacat accttggaac atccggaact ttccactagt cgcttcctca
     6181 agagaaattt cagtcaggtc tgaaaatact agtttagcat cattttcaat aacttgattg
     6241 ggctttccac cgagaacaaa ataatgtgac tcgtcaaaaa gtgtcaactg aacatcactc
     6301 ttttcagcaa ggtcatagag gtattcgatg tcagctggac taagttcttg ccagtcaacc
     6361 aagccccagt cgctagtctg gtgagttgaa caaccgttgt taacaatcac atactcattc
     6421 tggaggtcga gtcccagttt tttgtagtag gggaggacac cgaaaagggg gcgacccgta
     6481 cagagaacca gtttgacacc tttttcaatg gctttgtgaa tagcagtaat gtgagcttgt
     6541 gggatttcct tggcttcatt gaggagggtg ccgtccatat ccaaggctag tagtttaatc
     6601 ataggtcttc cttctttatc ttttgctatt attatagcat attttggaga agaaattgat
     6661 agaaagcttg agactaattg attttatagt ttaagatgtt ttgatgacaa ttcatgattt
     6721 gaagaggata tttggcaaag atatgctata ctatgtttgt caatgttgca actagacaaa
     6781 ttaaaaaacc aacttaatat aatagttttt ttgtaagtag gtatgagtat cagattactc
     6841 aactaatctg aagaataatg gaggaaatat atcatgattt taatgacaaa aaatataaat
     6901 ctaacaaatg aagaattaga gctgatacaa ggtggagcag attcatatgg taaaaatcct
     6961 aatggtaggt acgattggga aatagaacca gtattaactc tgccggttca tggattttgt
     7021 cccagaggca cctatgattt aggatatatt ggaggaggca atcatctttg caaaggaagt
     7081 gctgcgagat tttaagtaaa atttattagt aatatgaaga aacaagggga gaaagcagag
     7141 aatttaatat gaaaaaacgg gctattcaaa ttttactagc attgtcctta attttttaca
     7201 aatcaacttg gttttggaga gttttcaatc acctcgcaaa gccctatcta ccagcaagtc
     7261 gtgaattttt tcagattctg cttttgatgg agagcggagt tcttttctta gcggtcatct
     7321 atctactggt ttttgcagga aagaaaattt ttcatttcaa gtggcagctg aggtacttca
     7381 tctacctttt actgggctac atcatttcat atatgtctga cttcctcttt tcgtatttca
     7441 tatccctgtc ttcaaatcag atttctttga atgaaacgat agaaatgatg gggagacagg
     7501 agttccctta tttcttgctc atcgtttgct tcatcgcccc tattgctgag gaattgattt
     7561 atcgaggtgt gcttatgaca acctttttca aaaactcacc ttggtacgga gatgttttgc
     7621 tttctgctat tattttcggt tatattcata tcaattttgc tttaactcct cttgcttttt
     7681 tcatttatgc tagtagaggt ctgattttag ctctattgta tcgcatgact aaaaatctct
     7741 actatccaat actagttcat attctcatca atatcactgc cttctgggat gtttggttac
     7801 tcctattttc aggaagttag cttactaaaa aaatgtcgga attttccggc attttctttt
     7861 ttcacaaata gtcaacgttt ttctttccga tactgaagtg gtgtgtagcc acttattttt
     7921 ttgaattgat tttgaaaata agattggcgt gagaaaggca gatagtgaag atagttaaga
     7981 agaataggat gttctttttt cctttttgga aaacttctaa aatatggtat aatgaaaaga
     8041 taaagaagtt gggggtagaa gatgaacatt caacaattac gctatgttgt ggctattgcc
     8101 aatagtggta cttttcgtga agctgctgaa aagatgtatg ttagtcagcc gagtctgtct
     8161 atttctgttc gtgatttgga aaaagagttg ggctttaaga ttttccgtcg gaccagctca
     8221 gggactttct tgacccgtcg tgggatggaa ttttatgaaa aagcgcaaga attggttaaa
     8281 ggatttgata tttttcaaaa tcagtatgcc aatcctgaag aagaaaaaga tgaattttcc
     8341 gttgctagcc agcactatga cttcttacca ccaactatta cggccttttc agagcgctat
     8401 cctgactata agaacttccg tatttttgaa tcaactactg ttcaaatatt agatgaagtg
     8461 gcgcaagggc atagtgagat tgggattatc tacctcaaca atcaaaataa aaaggggatt
     8521 atgcaacggg ttgaaaagtt aggtctggag gtcatcgaat tgattccttt ccatacccat
     8581 atttatctct gtgagggtca tcctttagcc cagaaagagg aattagtcat ggaggattta
     8641 gcggatttac caacggttcg tttcactcaa gagaaagacg agtaccttta ttattcagag
     8701 aactttgtcg ataccagcgc tagctcacag atgtttaatg tgacagaccg tgccaccttg
     8761 aatggtattt tggagcggac ggacgcctat gcgacaggtt ctggattttt agatagtgac
     8821 agtgttaatg gcattacagt tattcgtctc aaggataacc tagataaccg catggtctat
     8881 gttaaacgtg aagaagtgga gcttagtcaa gctgggactc tcttcgtaga agtcatgcaa
     8941 gaatattttg atcaaaagag gaaatcatga aaaaaagagc aatagtggca gtcattgtac
     9001 tgcttttaat tgggctggat cagttggtca aatcctatat cgtccagcag attccactgg
     9061 gtgaagtgcg ctcctggatt cccaatttcg ttagcttgac ctacctgcaa aatcgaggtg
     9121 cagccttttc tatcttacaa gatcagcagc tgttattcgc tgtcattact ctggttgtcg
     9181 tgataggtgc catttggtat ttacataaac acatggagga ctcattctgg atggtcttgg
     9241 gtttgactct aataatcgcg ggtggtcttg gaaactttat tgacagggtc agtcagggct
     9301 ttgttgtgga tatgttccac cttgacttta tcaactttgc aattttcaat gtggcagata
     9361 gctatctgac ggttggagtg attattttat tgattgcaat gctaaaagag gaaataaatg
     9421 gaaattaaaa ttgaaactgg tggtctgcgt ttggataagg ctttgtcaga tttgtcagaa
     9481 ttatcacgta gtctcgcgaa tgaacaaatt aaatcaggcc aggtcttggt caatggtcaa
     9541 gtcaagaaag ctaaatacac agtccaagag ggtgatgtcg tcacttacca tgtgccagaa
     9601 ccagaggtat tagagtatgt ggctgaggat cttccgctag aaatagtcta ccaagatgag
     9661 tatgtggctg tcgttaacaa acctcaggga atggttgtgc acccgagtgc tggtcatacc
     9721 agtggaaccc tagtaaatgc cctcatgtat catattaagg acttgtcggg tatcaatggg
     9781 gttctgcgtc cagggattgt tcaccgtatt gataaggata cgtcaggtct tctcatgatt
     9841 gctaaaaacg atgatgcgca tctagtactt gcccaagaac tcaaagataa aaagtctctc
     9901 cgcaaatatt gggcgattgt tcatggaaat ctgcctaatg atcgtggtgt aattgaagcg
     9961 ccgattggcc ggagtgaaaa agaccgtaag aaacaggctg taactgctaa agggaagcct
    10021 gcagtgacgc gttttcacgt cttggaacgc tttggcgatt atagcttagt agagttgcaa
    10081 ctggagacag ggcgcactca tcaaatccgt gtccacatgg cttatatcgg ccatccagtc
    10141 gctggtgatg aggtctatgg tcctcgcaag actttgaaag gacatggaca atttcttcat
    10201 gccaagactt taggttttac tcatccgaga acaggtaaga ccttggaatt taaagcagat
    10261 atcccagaga tttttaagga aaccttggag agattgagaa agtaagaatg aaaaagaaat
    10321 taactagttt agcacttgta ggcgcttttt tagatttgtc atggtatggg aatgttcagg
    10381 ctcaagaaag ttcaggaaat aaaatccact ttatcaatgt tcaagaaggt ggcagtgatg
    10441 cgattattct tgaaagcaat ggacattttg ccatggtgga tacaggagaa gattatgatt
    10501 tcccagatgg aagtgattct cgttatccat ggagagaagg aattgaaacg tcttataagc
    10561 atgttctaac agaccgtgtc tttcgtcgtt tgaaggaatt gggtgtccaa aaacttgatt
    10621 ttattttggt gacccatacc cacagtgatc atattggaaa tgttgatgaa ttactgtcta
    10681 cctatccagt tgaccgagtc tatcttaaga aatatagtga tagtcgtatt actaattctg
    10741 aacgtctatg ggataatctg tatggctatg ataaggtttt acagactgct gcagaaaaag
    10801 gtgtttcagt tattcaaaat atcacacaag gggatgctca ttttcagttt ggggacatgg
    10861 atattcagct ctataattat gaaaatgaaa ctgattcatc gggtgaatta aagaaaattt
    10921 gggatgacaa ttccaattcc ttgattagcg tggtgaaagt caatggcaag aaaatttacc
    10981 ttgggggcga tttagataat gttcatggag cagaagacaa gtatggtcct ctcattggaa
    11041 aagttgattt gatgaagttt aatcatcacc atgataccaa caaatcaaat accaaggatt
    11101 tcattaaaaa tttgagtccg agtttgattg ttcaaacttc ggatagtcta ccttggaaaa
    11161 atggtgttga tagtgagtat gttaattggc tcaaagaacg aggaattgag agaatcaacg
    11221 cagccagcaa agactatgat gcaacagttt ttgatattcg aaaagacggt tttgtcaata
    11281 tttcaacatc ctacaagccg attccaagtt ttcaagctga ttggcataag agtgcatatg
    11341 ggaactggtg gtatcaagcg cctgattcta caggagagta tgctgtcggt tggaatgaaa
    11401 tcgaaggtga atggtattac tttaaccaaa cgggtatctt gttacagaat caatggaaaa
    11461 aatggaacaa tcattggttc tatttgacag actctggtgc ttctgctaaa aattggaaga
    11521 aaattgatgg aatctggtat tattttaaca aagaaaatca gatggaaatt ggttgggttc
    11581 aagataaaga gcagtggtat tatttggatg ttgatggctc tatgaagaca ggttggcttc
    11641 aatataaggg gcaatggtat tactttgctc catcagggga aatgaaaacg ggctgggtaa
    11701 aagataaaga agcctggtac tatatggatt ctactggtat catgaagaca ggtgagatag
    11761 aagttgctgg acatcattac tatctagaag aatcaggagc tatgaagcaa ggctggctta
    11821 aaaaggcaaa tgattggtat ttctacaaga cagatggttc acgagctata ggttggatta
    11881 aagataagga taaatggtac ttcttgaaag aaaatggtca attacttgtg aatggtaaga
    11941 caccagaagg ctatactgtg gattcaagtg gtgcctggtt agtggatgtt ccgatcgaga
    12001 aatctgctac aattaaaact acaagtcatt cagaaataaa agaatccaaa gaagtagtga
    12061 aaaaggatct tgaaaataaa gaaacgagtc aacatgaaag tgttacaaat tcttcaacta
    12121 gtcaagattt gacatcctca acttcacaaa gctctgaaac gagtgtaaac aaatcggaat
    12181 cagaacagta gtagaaaaga aggttttagg gccttctttt tcctatcaac tcttttctat
    12241 ttcctgttat tcatgttata atggataaat atgaataatc ggagtgagac tatgaaatac
    12301 aaacggattg tctttaaggt gggtacttct tctctgacaa atgaggatgg aagtttatca
    12361 cgtagtaagg taaaggatat tacccagcag ttggctatgc tgcacgaggc tggtcatgag
    12421 ttgattttgg tgtcttcagg tgccattgcg gctggttttg gagccttagg atttaaaaag
    12481 cgtccgacta aaattgctga taaacaggct tcagcagcgg tagggcaggg acttttgttg
    12541 gaagaatata cgaccaatct tctcttgcgt caaatcgttt ctgcacaaat cttgctgacc
    12601 caagatgact ttgtggataa gcgtcgttat aaaaatgccc atcaggcttt gtcggttttg
    12661 ctcaaccgtg gggcaattcc tatcataaat gagaatgata gtgtcgttat tgatgagctc
    12721 aaggttgggg acaatgacac tctaagtgct caagtagcgg cgatggtcca agcagacctt
    12781 ttagttttct tgacagatgt ggacggtctc tatactggaa atcctaattc agatccaaga
    12841 gccaaacgct tggagagaat cgagaccatc aatcgtgaga ttattgatat ggctggtgga
    12901 gctggttcgt caaacggaac tgggggtatg ttaaccaaaa tcaaggctgc aactatcgcg
    12961 acggaatcag gagttcctgt ttatatctgc tcatccttga aatcagattc catgattgag
    13021 gcggcagagg agaccgagga tggttcttac tttgttgctc aagagaaggg gcttcgtacc
    13081 cagaaacaat ggcttgcctt ctatgctcag agtcaaggtt ctatttgggt tgataaaggg
    13141 gctgcggaag ctctctctca acatggaaag agtcttctct tatctggtat cgttgaagta
    13201 gaaggagcct tttcttacgg tgatatcgtg acagtatttg acaaggaaag tggaaaatca
    13261 cttggaaaag gacgcgtgca atttggagca tctgctttgg aggatatgtt gcgttctcaa
    13321 aaagccaagg gtgtcttgat ttaccgtgac gactggattt ccattactcc tgaaatccaa
    13381 ctacttttta cagaatttta gaggtaaact atggtgagta gacaagaaca atttgaacag
    13441 gtacaggctg ttaaaaaatc gattaacaca gctagtgaag aagtgaaaaa ccaagccttg
    13501 ctagccatgg ctgatcactt agtggctgct actgaggaaa ttttagcggc taatgccctc
    13561 gatatggcag cggctaaggg gaaaatctca gatgtgatgt tggatcgtct ttatttggat
    13621 gcagatcgta tagaagcgat ggcaagagga attcgtgaag tggttgcctt accagatcca
    13681 atcggtgaag ttttagaaac aagtcagctt gaaaatggtt tggttatcac aaaaaaacgt
    13741 gtagctatgg gtgtcatcgg tattatctat gaaagccgtc caaatgtgac gtctgatgcg
    13801 gctgctttga ctcttaagag tggaaatgcg gttgttcttc gtagtggtaa ggatgcctat
    13861 caaacaaccc atgccattgt cacagccttg aagaagggct tggagacgac tactattcat
    13921 ccaaatgtga ttcaactggt ggaggatact agccgtgaaa gtagttatgc tatgatgaag
    13981 gccaagggct atctagacct cctcattcct cgtggaggag ctggcttgat caatgcagtg
    14041 gttgagaatg cgattgtacc tgttatcgag acagggactg ggattgtcca tgtctatgtg
    14101 gataaggatg cagacgaaga caaggcgctg tctatcatca acaatgctaa aaccagtcgt
    14161 ccttctgttt gtaatgccat ggaggttctg ctggttcatg aaaacaaggc agcaagcatc
    14221 cttcctcgct tggatcaaat gctggttgca gagcgtaagg aagctggact ggaaccaatt
    14281 caattccgct tggatagcaa agcaagccag tttgtttcag gtcaagcagc tgagacccaa
    14341 gactttgaca ccgagttttt agactatgtc cttgctgtta aggttgtgag cagtttagaa
    14401 gaagcggttg cgcacattga atcccacagc acccatcatt cggatgctat tgtgacggaa
    14461 aatgctgaag ctgcagcata ctttacagat caagtggact ctgcagcggt gtatgttaat
    14521 gcctcaactc gtttcacaga tggaggacaa tttggtcttg gttgtgaaat ggggatttct
    14581 actcagaaat tgcacgcgcg tggtccaatg ggcttgaaag agttgaccag ctacaagtat
    14641 gtggttgctg gtgatgggca gataagggag taagagatga agattggatt tatcggtttg
    14701 gggaatatgg gtgctagctt ggcaaaatct gtcttgcaga ctaggacgtc agatgagatt
    14761 ctccttgcca atcgtagtca agctaaggta gatgctttca ttgcagactt tggtggtcag
    14821 gcttccagca atgaagaaat gtttgcagaa gcagatgtga tttttctagg agttaagcct
    14881 gctcagtttt ctgaactgct ttctcaatac cagaccatcc ttgaaaaaag agaaagtctt
    14941 cttttgattt cgatggcagc tggattgacc ttagaaaaac tatcaagtct tatcccaagc
    15001 caacaccgaa ttattcgtat gatgcctaat acccctgctt ctatcgggca aggagtgatt
    15061 agttatgcct tgtctcctaa ttgcagggct gaggacagtg agatcttttg tcagctttta
    15121 gccaaggctg gtctcttggt tgaattagga gaaagcttaa tcaatgcagc gacaggtctt
    15181 gcaggttgtg gaccagcctt tgtctatctc tttattgagg ccttggcaga tgcaggtgtt
    15241 cagacgggat taccacgaga aacagccttg aaaatggcag cccaaactgt ggtaggagct
    15301 gggcaattgg tcctagaaag ccagcaacat cctggagttt tgaaagatca agtttgtagt
    15361 ccaggcggtt cgactattgc tggcgtagca agcctagaag cgcatgcttt tcgaggcaca
    15421 gtcatggagg cagttcatca agcctataaa cgaacacaag aactaggtaa ataagaggta
    15481 gctttgactg cctcttttat ggtggttgat actcttcgaa aatcaaattc aaactgcgtc
    15541 agcttcacct tgccgtactc aagtacagcc tgcggctagc ttcctagttt gctctttgat
    15601 tttcattgag tatgaaatga gaagacaaaa agattgtcac aaacccctat ttttttgata
    15661 gaatagaagt agtaaaaaag aaatgagtta gacatgtcaa aaggattttt agtctctctt
    15721 gagggaccag agggagcagg caagaccagt gttttagagg ctctgctacc aattttagag
    15781 gaaaaaggag tagaggtgtt gacgacccgt gaacctggcg gagtcttgat tggggagaag
    15841 attcgggaag tgattttgga tccaagtcat actcagatgg atgctaaaac agagctactt
    15901 ctctatattg ccagtcgcag acagcatttg gtggaaaaag ttcttccagc ccttgaagct
    15961 ggcaagttgg tcatcatgga tcgttttatc gatagttctg ttgcctatca gggatttggt
    16021 cgtggcttag atattgaagc cattgactgg ctcaatcagt ttgcgacaga tggcctcaaa
    16081 cccgatttga cactctattt tgacatcgag gtggaagaag ggctggctcg tattgctgct
    16141 aatagtgacc gcgaggttaa tcgtttggat ttggaagggt tggacttgca taaaaaagtt
    16201 cgtcaaggct acctttctct tctggataaa gagggaaatc gcattgtcaa gattgatgct
    16261 agtctccctt tggagcaagt tgtggaaact accaaggctg tcttatttga cggaatgggc
    16321 ttggccaaat gaaacaagat caactaaagg cttggcaacc agctcagttt gaccgttttg
    16381 tccgtatctt agaacaagac cagctcaatc acgcctatct cttttcaggt ttctttgaaa
    16441 gcttggaaat ggcgcaattt ttagctaaga gcctcttttg tacggataaa gttggcgtct
    16501 taccatgtga gaaatgccga agttgcaagc tgattgaaca gggagagttt ccagatgtca
    16561 ccttgattaa gccagtcaat caggtcatca agacagaacg cattcgggaa ttggtgggac
    16621 agttttctca agcagggatt gaaagccagc aacaggtctt tatcatcgag caagcggata
    16681 aaatgcatcc caacgcagcc aattctctgc tcaaggtcat cgaagaaccc cagagtgaag
    16741 tttatatttt cttcttgact agcgatgagg aaaagatgtt accgacaatc cgaagtcgga
    16801 ctcagatctt ccactttaaa aagcaagaag aaaaacttat cttactctta gaacaaatgg
    16861 gacttgttaa gaaaaaagcg actcttttag ctaagtttag tcaatcgcga gctgaagcag
    16921 aaaagttggc taatcaggca agtttttgga ccttggtcga tgaaagtgaa cgcctgctga
    16981 cttggttagt agctaagaaa aaagaaagtt atctacaggt tgccaaatta gccaacttgg
    17041 cagatgataa ggaaaaacag gatcaggttt tacggattct tgaagttctc tgtgggcagg
    17101 acctcttgca ggtaagagta agagtgattc tacaagattt actagaagct agaaaaatgt
    17161 ggcaagctaa tgtcagcttt caaaatgcca tggaatatct ggtcttgaaa gaaatataaa
    17221 ctcaaaaatg aatgataaag aaaggaaagg gctgttttat ggacaaaaaa gaattatttg
    17281 acgcgctgga tgatttttcc caacagttat tggtaacctt ggccgatgtg gaagccatca
    17341 agaaaaatct caagagcctg gtagaggaaa atacagctct tcgtttggaa aattctaagt
    17401 tgcgagaacg cttgggtgag gtggaagcag atgctcctgt caaggccaag catgttcgtg
    17461 aaagtgtccg tcgcatttac cgtgatggat ttcacgtatg taatgatttt tatggacaac
    17521 gtcgagagca ggacgaagaa tgtatgttct gtgatgagtt gttatacagg gagtaggcat
    17581 gcaaattcaa aaaagtttta aggggcagtc tccctatggc aagctgtatc tagtggcaac
    17641 gccgattggc aatctagatg atatgacttt tcgtgctatc cagaccttga aagaagtgga
    17701 ctggattgct gctgaggata cgcgcaatac aggtcttttg ctcaagcatt ttgacatttc
    17761 caccaagcag atcagttttc atgagcacaa tgccaaggaa aaaattcctg atttgattgg
    17821 tttcttgaaa gcagggcaaa gtattgctca ggtctctgat gccggtttgc ctagcatttc
    17881 agaccctggt catgatttag ttaaggcagc tattgaggaa gaaattgcag ttgtgacagt
    17941 tccaggtgcc tctgcaggaa tttctgcctt gattgccagt ggtttagcgc cacagccaca
    18001 tatcttttac ggttttttac cgagaaaatc aggtcagcag aagcaatttt ttggcttgaa
    18061 aaaagattat cctgaaacac agatttttta tgaatcacct catcgtgtag cagacacgtt
    18121 ggaaaatatg ttagaagtct acggtgaccg ctccgttgtc ttggtcaggg aattgaccaa
    18181 aatctatgaa gaataccaac gaggtactat ctctgagtta ttagaaagca ttgctgaaac
    18241 gccactcaag ggcgaatgtc ttctcattgt tgagggtgcc agtcagggtg tggaggaaaa
    18301 ggacgaggaa gacttgttcg tagaaattca aacccgcatc cagcaaggtg tgaagaaaaa
    18361 ccaagctatc aaggaagtcg ctaagattta ccagtggaat aaaagtcagc tctacgctgc
    18421 ctaccacgac tgggaagaaa aacaataaag ggagacagga tgtaataatt ctgtctgttt
    18481 ctgtttaact taattagtga tggtaatata aagatgtatc acttggtata gaagctttgg
    18541 tattaagttt tttattaagc ccatacggaa taccgatggt tggagcagca gttatagcgt
    18601 tcttagaagg tataaataga aaaataaggt cattttaaat caaaggattg ataaatcaga
    18661 aagaaggtga ttttttgcga acatacgaaa ataaagaaga actaaaagct gagatagaga
    18721 aaacatttga gaaatatatt ttagaatttg ataatattcc agaaaattta aaagataaga
    18781 gagctgatga agttgacaga actccagcag aaaaccttgc ttatcaggtt ggttggacca
    18841 acttggttct taaatgggaa gaagatgaaa gaaaggggct tcaagtaaaa acaccatcgg
    18901 ataaatttaa atggaatcaa cttggtgaat tatatcagtg gttcacagat acctacgctc
    18961 atttatctct gcaagagttg aaagcaaaat taaatgaaaa tattaattct atctctgcaa
    19021 tgattgattc gttgagtgag gaagaattat ttgaaccgca tatgagaaag tgggctgatg
    19081 aagcgactaa aacagcgact tgggaagtgt ataagtttat tcatgtaaat acggttgcac
    19141 cttttggaac tttcagaact aaaatcagaa aatggaagaa gatagtatta taaattatat
    19201 ttttaacttt aaaaaatttc ataaaaatgg ttaccaaagg cgatagaaga aaaactatcg
    19261 tctttttctt tgcaaatttt taagaaggga ggtgatcttg catggacttt gaatattttt
    19321 ataacagaga agcggaaaga tttaacttct taaaagtacc ggagatatta gttgatagag
    19381 aagaatttcg gggcttatca gcagaagcaa ttatccttta ttccatactt cttaaacaga
    19441 caggaatgtc atttaagaat aactggatag acaaggaagg cagagtattt atctttactg
    19501 tcgaagaaat tatgaaaaga agaaatatct caaagccaac tgccataaaa acattagatg
    19561 agcttgatgt aaaaaaagga ataggactga tcgaaagagt aaggcttgga cttggtaagc
    19621 cgaacatcat ttatgttaaa gactttatga gtatatttca ggtaaaagaa aatgacttac
    19681 agaagtcaaa aaacttaact tcagaagtaa aagattttaa cctcagaagt aaagaaaatg
    19741 aacttcaaga ggttaagaac cttgactcta actatataga gaataataag agtaagtata
    19801 gtaagagaga atatagtttt ggtgaaaacg gacttggaac atttcaaaat gtgtttttag
    19861 ctgctgaaga tatatcggat ttacaaatca taatgaactc acagcttgag aattacatta
    19921 gacttcctgc aaaactagaa tcctagttca tgattgataa taccagcaat caaattcatt
    19981 cgtaatccga agcgtttacg atgatttcga taggttgttg aaatcatttt aaacgttttt
    20041 actttggcaa agatgttctc aaccttgctt ctctccttgg atagcgcatg gttacaggct
    20101 ttatcttcaa ctgttagtgg cttgagtttg ctggatttac gtggagtttg tgcttgagga
    20161 tatatcttca tgagcccttg ataattactg tcagccaaga ttttaccagc ttgtccgata
    20221 tttccgcgac tcattttgaa caacttcata tcatgacaat agttcacagt gatatccaaa
    20281 gaaataattc ttccttgact tgtgacaatc gcttgagcct tcatagcgtg gcatttcttt
    20341 ttaccagaat cattcgctaa ttgttttttt aggtcgattg atttttactt ccgtcgcatc
    20401 aatcattacc gtgtcctcaa aactaagagg agttcttgaa atcgtaacac cactttgaac
    20461 aagagttact tcaacccatt ggctccgacg gattaagttg ctttcgtgga taccaaaatc
    20521 agccgcaatt tcttcataag ttcaatattc tcgcacatat tgaagagtgg ccataagaag
    20581 gtcttctagg cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt
    20641 ttttaataca gctaacatct cttcaaaagt ggtacgctga acaccaacaa gacgcttaaa
    20701 tcgtgtatca gttaattgtt tacttgcttc ataattcata gaactactat accatatttt
    20761 gtttcgcagg aagtctattg gaaagtaaga aatattgaag ctgaggctat tagaagaaat
    20821 tgtgagcgtg gtgctatttt ttcaggtaaa aataaaatat cacgaagatt cacagtttaa
    20881 aggagatcac tatgttgaat gttatgctgt tttagataat acggttatag caagagatag
    20941 aataacagtc cctatcgatc cgttatgtgg aaaagatttt atagagtagc atataattga
    21001 ttcttaactg gaatactcac tatctcttta catcaagaaa atgactaaac agggaagttt
    21061 gccttcttcc ctttttttgt tatactagta gaagaaaaaa tagaaagatt tgtgggagtg
    21121 aaaaagtcct gtggactttt tcagcctgag ccaagaaact cgaaagctcg taagtctgat
    21181 tggctttttc aatgtgaatc ttaacttcac actcccaaag aggtattagt gtcgtgtctc
    21241 aatcttatat caatgttatc ggtgctggtt tggcaggttc tgaagcagct taccaaatcg
    21301 cagagcgtgg tattccagtt aaactttatg aaatgcgtgg tgtcaagtcg actcctcagc
    21361 ataaaacaga caattttgct gagttggttt gttccaattc tttgcgtggg gatgctttga
    21421 caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt gggttctgtt atcttggaat
    21481 ctgctgaggc tacacgtgtt cctgccggtg gagcccttgc ggtggatcgt gatggtttct
    21541 cccaaatggt aaccgaaaaa gtggtcaacc accccttgat tgaagtggtg cgtgatgaaa
    21601 ttacagaatt gccaacagat gttattacag ttgtggcgac cggtcccttg actagcgatg
    21661 ccctggctga aaagattcat gcccttaatg atggcgatgg cttctatttc tacgatgcag
    21721 cagcgcctat tatcgatgtc aacactatcg atatgagtaa ggtctatctc aaatctcgtt
    21781 atgataaggg agaagcagcc tatctcaatg ctccaatgac caagcaagag tttatggatt
    21841 tccatgaagc cttggtcaat gcggaagaag caccgctcaa ttcttttgaa aaagaaaagt
    21901 actttgaagg atgtatgcca atcgaagtta tggccaaacg tggcattaaa actatgcttt
    21961 atggccctat gaagccagtc ggtcttgagt atccggacga ctacacagga cctcgtgatg
    22021 gagaatttaa aacaccttat gcggttgtgc aacttcgtca ggataatgca gctggtagcc
    22081 tctacaatat cgttggtttc cagacccacc tcaaatgggg agaacaaaag cgtgtcttcc
    22141 aaatgattcc gggtcttgaa aatgcggagt ttgtccgtta tggtgtcatg catcgcaatt
    22201 cttacatgga ttcaccaaat cttcttgagc agacttaccg ttccaagaaa caaccaaatc
    22261 tcttctttgc tggtcagatg acgggggtgg aaggctatgt tgagtcggcg gcttcgggct
    22321 tagttgcggg aattaacgca gctcgtctct tcaaggaaga aagcgaggtt attttccccg
    22381 agacgacagc gattggaagc ttagctcatt acattaccca tgccgacagc aaacatttcc
    22441 aaccaatgaa tgtcaatttt gggatcatca aggagttgga aggcgagcgt atccgtgata
    22501 agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc cgacttagag gaatttttga
    22561 ctgtctaatt tttttgaaag aattgctcat gatactataa aaatcttaga aattgtgata
    22621 aaataggtag gatgaaagaa ggagagtgaa aatggcgaat cccaagtata aacgtatttt
    22681 aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc gtagggattg atatccaaac
    22741 agttcaaaca atcgcaaaag agattcaaga agttcatagc ttaggtatcg aaattgccct
    22801 tgttattggt ggaggaaatc tctggcgtgg agaacctgca gcagaagcag gtatggaccg
    22861 tgttcaggca gattacactg gaatgcttgg gactgttatg aatgctcttg tgatggcaga
    22921 ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca gctattgcta tgcaacaagt
    22981 ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt gaaaaaggcc gtatcgttat
    23041 ctttggtgct ggaattggtt caccatactt ctcgacagat acaacagcgg cccttcgcgc
    23101 agctgaaatc gaagcagatg ccatcctcat ggctaaaaat ggcgtcgatg gtgtgtacaa
    23161 tgccgatcct aagaaggaca agacagccgt taagtttgaa gaattgaccc accgtgatgt
    23221 tatcaacaaa ggtcttcgta tcatggactc aacagcctca accctctcaa tggacaacga
    23281 cattgacttg gttgtcttca acatgaacca atcaggcaac atcaaacgtg tcgtatttgg
    23341 tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa aaggaataag aaagaatatg
    23401 gctaacgtaa ttattgaaaa agctaaagag agaatgaccc agtctcacca atcacttgct
    23461 cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa gcttgcttga ccgtgtacat
    23521 gtagaatact atggagtcga aactcctctt aaccaaatcg cttcaattac gattccagaa
    23581 gcgcgtgttt tgttggtaac accatttgac aagtcttcat tgaaagacat cgaacgtgcc
    23641 ttgaacgctt ctgatcttgg tatcacaccg gctaatgacg gttctgtgat tcgcttggtt
    23701 atcccagctc ttacagaaga aactcgtcgt gaccttgcta aagaagtgaa gaaggtcggc
    23761 gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg ctatggacga agctaagaaa
    23821 caagaaaaag caaaagaaat cactgaagac gaattgaaga ctcttgaaaa agatattcaa
    23881 aaagtaacag acgatgctgt taaacacatc gacgacatga ctgctaacaa agagaaagaa
    23941 cttttggaag tctaaaaata aacagaaaaa ctcagttggc attgctggct gagttttatt
    24001 cgaaagaagg aaatatgaat acaaatcttg caagttttat cgttggactg atcatcgatg
    24061 aaaatgaccg tttttacttt gtgcaaaagg atggtcaaac ctatgctctt gctaaggaag
    24121 agggccaaca tacagtaggg gatacggtca aaggttttgc atacacggat atgaagcaaa
    24181 aactccgcct gacaacctta gaagtgactg ccactcagga ccaatttggt tggggacgtg
    24241 tcacagaggt tcgtaaggac ttgggtgtct ttgtggatac aggccttcct gacaaggaaa
    24301 tcgttgtgtc actcgatatt ctccctgagc tcaaggaact ctggcctaag aagggcgacc
    24361 aactctacat ccgtcttgaa gtggataaga aagaccgtat ctggggcctc ttggcttatc
    24421 aagaagactt ccaacgtctt gctcgtcctg cttacaacaa catgcagaac caaaactggc
    24481 cagccattgt ttaccgtctc aagctgtcag gaacttttgt ttacctacca gaaaataata
    24541 tgcttggttt tattcatcct agcgagcgtt acgcagagcc acgtttgggg caagtattag
    24601 atgcgcgcgt tattggtttc cgtgaagtgg accgcactct gaacctctcc ctcaaaccac
    24661 gctcctttga aatgttggaa aacgatgctc agatgatttt gacttatttg gaaagcaatg
    24721 gcggtttcat gaccttaaat gacaagtcat ctccagacga catcaaggca acctttggca
    24781 tttctaaagg tcagttcaag aaagctttag gtggtcttat gaaggctggt aaaatcaagc
    24841 aagaccagtt tgggacagag ttgatttagg gaggcttatg agaaaatcat tttacatttg
    24901 gctcatgacc gagcgcaatc ctaaaagtaa cagtcccaaa gcaattttgg cagacctcgc
    24961 ttttgaagag tcagcctttc caaaacatac agatgatttt gatgaggtca gtcgcttttt
    25021 ggaggagcat gccagtttct cttttaacct aggagatttt gacagcattt ggcaggaata
    25081 tctagaacac tagcatttat tcattgggtt tgggctagta atttctccat ccctctgcta
    25141 taataaaaag aaataaaagg attagagagg ttctttattt gaaggaacat tcaatagaca
    25201 ttcaactgag tcatccagat gacctgtttc atctttttgg ttccaatgaa cgccatcttc
    25261 gtttgatgga agaagagctt gatgttgtga ttcatgctcg tacggagatt gtccaggttt
    25321 tgggagaaga gtctgcttgc gaggaagccc gtcaggttat tcaagctctc atggccttgg
    25381 taaatcgtgg gatgaccgtt ggtacgccag atgtagtgac ggctattagt atggtcaaaa
    25441 atgatgaaat tgacaagttt gtcgcccttt acgaagaaga aatcatcaag gataatactg
    25501 ggaagcctat ccgcgtcaaa accttaggtc aaaaacttta tgtggacagt gtcaaacagc
    25561 atgatgtgac ctttggaatt gggccggcag gtacagggaa gaccttcctt gcagtgacct
    25621 tggcagtgac tgcccttaaa cgtgggcaag tcaagcgaat tatcctaact cgtccagcgg
    25681 tggaagcggg agagagtctt ggatttcttc cgggtgatct taaggagaag gtggatcctt
    25741 accttcgtcc tgtttacgat gccttgtatc aaattcttgg gaaagaccaa acgactcgtc
    25801 tcatggagcg tgaaattatc gaaattgcgc cccttgccta tatgcgtggc cggaccttgg
    25861 atgatgcctt tgtcattctc gatgaggcgc aaaacacgac catcatgcag atgaagatgt
    25921 tcttgacgcg tttaggcttt cattctaaga tgattgtcaa tggagatatc agtcagattg
    25981 acctgccacg taatgtcaag tccggtttga ttgatgctca agagaaactc aagaacatcc
    26041 atcagattga ctttgttcat ttttcagcta aggatgtggt tcgccatcca gttgtcgctc
    26101 aaattatccg agcctatgaa tattctactg aagttgcaca cgactgattt tgaggaagtt
    26161 cgcctgcaaa agaatatact tttgagagag gaaaatccag ttgtataggc taaaggtttt
    26221 atccaaaggt ttgagacaac gattaggcac gatggaaaga acttttatgt ggctgatgac
    26281 gatcagtgca tcttcctgtg tcataatcac agggaacaag aaagtaggaa tttgaaaaga
    26341 tgattgacca actatctaag tattacagtt gtaggatact aactgaaaag gatattccaa
    26401 gtattttatc tttatatgaa agtaatcctc tgtattttca gcattgtcca ccagagccaa
    26461 attttgcaac tgtaaaagag gacatgcttt gtctacctga aggtaaagct aaggctgata
    26521 agttttttgt tggattttgg aatggctctg accttgtggc tgttatggat tttgtctatg
    26581 catatcctga tgaggagact gtttttattg gtttgtttat ggttgatcaa gcctatcaga
    26641 ggaaagggat tggtagtcat attgtgacag aagcactagc ttattttgct aagaactttc
    26701 gaaaggcacg tttggcttat gttaagggaa atccgcaatc tcagcatttt tgggaaaagc
    26761 agggctttaa atcaattgga tgcgaggtta agcaagaact ctatacggtt gttatcgttg
    26821 aacagagcct agaagattag aaatggcatc aagtaagaac tatttggaat ttgttttgga
    26881 acaattatca ggattagatg atgtgactta ccgttccatg atgggggagt atattcttta
    26941 cttccgcggc aagattattg gcggtattta tgacgatcgc ttttagttaa acccgtgcaa
    27001 gcagtcttag ataagattga ccaatcttct tttgagtttc catacaaagg tgccaaagaa
    27061 atgatttgag tggaagaact tgataataag atgtttctat aagacctgat tttagctatg
    27121 tataaccaac tgccaacgcc caaacctaaa aagaaaaagc aagggtgaac gaagtaaaaa
    27181 agaagtctgc taaggccctg tctttgcacg ggtaaaattt tatatataaa aagaagctgg
    27241 gactaaagag ctcagcttcc tttggtttat ataattgtca ttacaagacg aagtggttgg
    27301 gcgaaactct gttgacttta ttcaatttag agtttcttat gcacaattga gtctggaacg
    27361 aaagtctcca gttgcaaagt atacagtaca ataaaccaac gatgtaatag ctgatgacac
    27421 aaagcacagt gggtaggact tgcgaagtca cccttttctt ttcaaaattt atactaaatc
    27481 attgatatca gtgtagtcac gattaagtcc ttgagcaact ggtaggctag tcaagtaacc
    27541 ttgataagtg gtcacacctt gacgcaagcc ttcatcttca gagattgctt gtgcgaatcc
    27601 tttgccagcc aaagcttcga tataaggaag agtgacattg gttagggcga tggttgaagt
    27661 gcgagcaacc gcaccaggga tattggcaac ggcatagtgg agaacaccgt gtttttcata
    27721 gacgggttca tcgtgcgttg tcacacggtc agctgtttcg ataaggccac cttggtcaac
    27781 agcaaggtca acgatacaga gcctggacgc atttgtttga ccatctcatc tgtcaccaat
    27841 tccggtgctt ttgcaccagg gatgagaatg gctccaatca ccacatcagc atctctcaca
    27901 cttgcttcaa tgttgaatga attagatata agagtttaaa tttgacttcc aaagacttct
    27961 tttagaactg agagacgctt ggcactaata tctaaaatag tcacttgagc accaagacca
    28021 agggcgatgc gggcagcatg tgtactgacg acaccatcac cgatgatagt tacttttcct
    28081 tttggaacac ctggtacacc accaggtaga acaccagagc caccagcttg cttagtaagg
    28141 aagtgagctc cgatttaaac agccatacga tctgcaacct cactcatagg aacgaggagc
    28201 ggtagttgtc cttgattgtc acgaacagtt tcataggcaa ttcctgttgt ttttgctgct
    28261 aacatagcat ctgctaattc tggagcagcg gccatgtgca agtaggtgaa gagaagaaga
    28321 tcgtcgcgaa agtaaccgta ttcagaactt aaaggttctt ttactttcac aaccaactct
    28381 gctgcccaag cttcaccagc agtagcgaca atctcagctc cttgcttttg atagtcagca
    28441 tcagtaaagc cagaaccgag accagcattt gtttcgataa ggacacgatg accacgacta
    28501 actaagctat gaacacctgc aggtgtgagg gcgacacggt tttcgttatt tttaatttct
    28561 tttgggattc cgattaacat tgagataacc tacctttcaa ttgacggtct tgttttggtt
    28621 gtcacattcc agttcataaa tcaaaaatgt gacggtttca ttgtatatga aaccgcttca
    28681 aaaatcaaga aaaacttgtc atccaaattt tttatgctag actagtgaaa atcaagcttt
    28741 gattggttgg aaaagtatgg aatcaatttt tgtaaaactt gcccagtatc cgtctataga
    28801 aacggagcgt ttattgctta gacctgtaac tttggatgat gcggaagcaa tgtttgacta
    28861 tgcctcggac aagggtaata cacgttacac ttttccaacc aatcaaagtt tggaagaaac
    28921 caagaataac attgctcagt tctatttggc taatcccttg ggacgttggg gaatagaact
    28981 aaaaagcaat ggtcagttta ttggaaccat tgacttgcac aagattgatt ctgttcttaa
    29041 gaaggcagct attggctaca ttatcaataa aaagtattgg aatcaaggat taacgacaga
    29101 agccaatcgt gctgtgattg agctagcttt tgagaagata gggatgaata agttgactgc
    29161 ccttcacgat aaggacaatc ctgcgtcagg aaaggtcatg gagaaatcag gcatgcgttt
    29221 ttcccatgca gaaccatatg cttgtatgga ccagcatgaa aaaggccgaa tcgtgacaag
    29281 agttcattat gtcttgacca aggaagacta ttttgcaaat aaataagcag ttgaaaagaa
    29341 atttttcgac tgttttttct tcctcttacg aataatctaa gagaggagaa aatatggaag
    29401 caattatcga gaaaatcaaa gagtataaaa tcatcgtcat ctgtactggt ctgggcttgc
    29461 ttgtaggagg atttttcctg ctaaaaccag ctccacaaac acctgtcaaa gagacgaatt
    29521 tgcaggctga agtcgcagct gtttccaagg atttggtatc cgaaaaggaa gtgaacaagg
    29581 aagaaaagga agaacccctt gaacaagatc taatcacagt agatgtcaaa ggtgctgtca
    29641 aatcgccagg gatttatgac ttgcctgtag gtagtcgagt caatgatgct gttcagaagg
    29701 ctggtggctt gacagagcaa gcagacagca agtcgctcaa tctagctcag aaagttagtg
    29761 atgaggctct ggtttacgtt cctactaagg gagaagaagc agttagccaa cagactggtt
    29821 tggggacagc ttcttcaata agcaaggaaa agaaggtcaa tctcaacaag gccagtctgg
    29881 aagaactcaa gcaggtcaag ggactgggag gaaaacgagc tcaggacatt atcgaccatc
    29941 gtgaggcaaa tggcaagttc aagtcagtag acgagctcaa gaaggtctct ggcattggtg
    30001 gcaaaacaat agaaaagctt aaagactatg ttacagtgga ttaagaattt ctctattccc
    30061 ctaatttacc tgagttttct gttactttgg ctttactacg ctattttctc agcatcctat
    30121 cttgctttgt tgggatttgt ttttctgcta gtctgtctct ttttccaatt tccttggaaa
    30181 tctgctagca aagttctagt gatttgtgga atctttggat tttggtttgt ttttcaaaat
    30241 tggcaacaga gtcaagcgag tcaaaatctg gcggattctg ttgaaagggt acggattttg
    30301 cctgatacta ttaaggtcaa tggtgatagt ctatcctttc gtggcaagtc taacggtcgt
    30361 gctttccaag tctattataa actccagtcc gaggaggaga aagaagcctt tcaagcttta
    30421 accgacctgc atgagatagg actagaaggg aagctttcgg agccagaagg gcagagaaat
    30481 tttggtggct ttaattacca agcctatctg aagactcagg gaatttacca gacactcaat
    30541 attaaaagaa tccagtcact ccaaaaggtt ggcagttggg atataggtga aaaactgtcc
    30601 agtttacgtc gaaaggctgt ggtttggatt aagatgcact tcccagaccc tatgcgcaat
    30661 tacatgacag gactcttgct aggacatctg gacaccgatt ttgaggagat gaatgagctt
    30721 tattccagtt taggaattat tcaccttttt gccttgtcag gtatgcaggt agggtttttc
    30781 atgaatggat ttaagaaact tctcttgcga ttgggcttga cccaagaaaa gttgaaatgg
    30841 ctgacttatc ccttttccct tatctatgcg ggactaactg gattttcagc atcggttatt
    30901 cgcagtctct tgcaaaagct actggctcaa catggggtta agggcttgga taattttgcc
    30961 ttgacggtgc ttgtcctctt tattgtcatg ccaaactttt tcttgacagc aggaggagtc
    31021 ttgtcctgcg cttatgcttt tatcctgacc atgaccatta aagaagggaa ggggctcaag
    31081 gctgttgcta gtgaaagtct agtcatctcc ttgggcatat tgcccattct atccttctat
    31141 tttgcggaat ttcaaccttg gtctatcctt ttgacctttg tcttttcctt tctatttgac
    31201 ttgaccttct taccgctcct gtctatttta tttgtccttt cctttctcta tccagtcatt
    31261 cagctgaact ttatctttga atggttggag ggcattattc gcttggtctc acaggtgaca
    31321 agtaggcctc tagtctttgg acaacccaat gaatggcttt taatcctatt gttaatttct
    31381 ttggctttgg tctatgattt gaggaaaaac attaaaggat taacagtatt gagtttattg
    31441 attacaggtc tctttttctt gaccaagtat ccactggaaa atgaaatcac catgctggat
    31501 gtggggcaag gagaaagtat tttcctacgg gatgtaactg ggaaaaccat tctcatagat
    31561 gtaggtggta aggcagaatc ttataagaaa atcgaaaaat ggcaagaaaa gatgacgacc
    31621 agcaatgccc agcgaacctt gattccctat ctcaaaagtc gaggagtagc taagattgac
    31681 cagctaattt tgactaacac ggacaaggag catgttggag atttgtcaga ggtgaccaag
    31741 gctttccatg taggggagat tttagtatca aaaggcagtt tgaagcagaa gcaatttgtg
    31801 gtagaactac aggcgactaa aacaaaggtg cgtagtatga cagtagggga gaacttgccc
    31861 atttttggaa gtcagttaga agttctatct ccaaggaaaa tgggagatgg aggacacgat
    31921 gataccctag ttctgtatgg gaaattcttg gataagcaat ttctcttcac gggaaatttg
    31981 gaggagaaag gagagaagga cttgctgaag cactatccag acttgaaagt aaatgttttg
    32041 aaagctagcc aacatggcaa taaaaaatca tcaagcccag cctttctaga aaaactcaaa
    32101 ccagagctta ctcttatctc agttggaaag agcaatcgaa tgaaactccc ccatcaggaa
    32161 acattgacac gactggaagg tatcaatagc aaagtttatc gaactgacca gcaaggagct
    32221 atacgtttta aggggttgga tagttggaaa atcgaaagtg ttcgatagga aagataaatg
    32281 ttgtagatta gtgaaataaa ctaaaaattt gttgcataat aatgataaaa atggtataat
    32341 gaaaacgtat tcaatattga ggatataaaa tcattaaaaa tcagcaaaag ttattttatt
    32401 agttagttta taatctattg gtcttcttca gtccagtgta tctgctaaga gtgttcttaa
    32461 aagtatcggt atgattggaa tatcttctat aagtctagta tgaatttcca tggatataga
    32521 catactaacg ttccgtcatg gtctcgttat tacagctatt ctgagtatcc agttggttct
    32581 ggctggaact acggtcgtta tgagatcata aactattaca gcggaggcta ttaattctta
    32641 aagagtgaga aaaaggaggg ctagatatgt tgcagcttac tcatgtgacc ttaaaaacgc
    32701 gacaagtcat cttgcaagat gcggatttca cctttaaaaa gggtaggttt tatggtcttc
    32761 ttgctatcaa tggctctgga aagacgaccc tgttccgtgc cattagcaat ttaattccca
    32821 taagtagtgg aaatatcgca gcccctcctt ctttatttta ttatgagagt attgaatggc
    32881 tggatggaaa cttaagtggg atggactacc ttcgtcttat caaaaacatc tggaagtcag
    32941 acctaaactt gagagatgaa atcgcctact gggaaatggc tgactatatc agtcttccca
    33001 tccgcaagta ttccttaggc atgaagcaac gcttggtgat tgctatgtat tttctcagtc
    33061 aggcaaaatg ctggctcatg gatgagatta caaatggctt agacgagtat tatcgacaga
    33121 agttttttga taggctagca caaatcgata gacaagaaca gctggttctt ttaagttccc
    33181 actataagga agagttggtt gatatctgcg atagagtagt aaccattcat caggggcaga
    33241 tagaagaggt ttagtttatg aaagatgtta gtctattttt attgaaaaaa gttttcaaaa
    33301 gtcgtttaaa ctggattatc ttacttttat ttgcatctgt actcggtgtt accttttatt
    33361 taaatagtca gactgcaaac tcacacagct tggagagcag gttggaaagt cgcattgcag
    33421 ccaacgagag agccatcaat gaaaatgaag cgaaactttc ccaaatgtct gacaccagct
    33481 cggaggaata ccagtttgct aaaagtaatt tagaattgca aaaaaatctt ttgaagcgaa
    33541 agacagaaat tctgacttta ttaaaagaag ggcgctggaa agaggcctac tatctgcagt
    33601 ggcaagatga agagaagaat tatgaatttg tatcaaatga cccgactgct agctctggct
    33661 taaaaatggg ggttgaccgc gaacggaaga tttaccaagc cctgtatccc ttgaacataa
    33721 aagcacatac tttggagttt ccgacccacg ggattgatca gattatctgg attttagagg
    33781 ctatcatccc aagcttgttt gtggttgcta ttatttttat gctaacacaa ctatttgcag
    33841 aaagatatca aaatcatctg gacacagctc acttatatcc tgtttcaaaa gtgacatttg
    33901 caatgtcttc tcttggagtt ggagtgggct atgtaactgt gctgtttatc ggaatctgtg
    33961 gcttttcttt tctagtggga agtctgataa gtggttttgg acagttagat tatccctacc
    34021 cgatttatag cttagtgaaa caagaggtaa ctattggaaa gatgcaggat gtattatttc
    34081 ctagcttgct cttagctttc ttagccttta tcgtcattgt ggaagttgtg tatttgattg
    34141 cttacttttt caagcaaaaa atgcctgtcc tctttctttc actcattggg attgttggct
    34201 tattgtttgg catccaaacc attcagcctc ttcaaaagat tgcacatctg attcccttta
    34261 cttacttgcg ttcagtggag attttatctg gaagattacc taagcagatt gataatgtcg
    34321 atctaaattg gagcatggga atggtcttac ttccttgcct gattatcttt ttgctattgg
    34381 gaattctatt tattgaaaga tggggaagtt cacagaaaaa aagaattttt taatagattc
    34441 tagctttcct ataggtaggg aaaataagta aaaactaaca tagagaggga atcaacttga
    34501 ttctctcttt ttgatttgaa aaccaaacca aaatacaaac acaaactttt caaaaaataa
    34561 ctttttatct tgacaagagc tagaaaactt ggtatcatat aaaagttgag aaaagcagaa
    34621 gtgagagctt ctcgccttgt gacattaagt tgcctggccc tacggatgaa aagtttcgaa
    34681 gaaacgctat cataacgtgc gggcttgtat atttacgagt ccgctattgt ttttctctaa
    34741 taaaacaaaa gaggtgaaaa ccatagcaaa gcaagactta ttcatcaatg atgagattcg
    34801 tgtacgtgaa gttcgcttga ttggtcttga aggagaacag ctaggcatca agccactcag
    34861 tgaagcgcaa gctttggctg ataacgctaa tgttgaccta gtattgattc aaccccaagc
    34921 caaaccgcct gttgcaaaaa ttatggacta cggtaagttc aaatttgagt accagaagaa
    34981 gcaaaaagaa caacgtaaaa aacaaagcgt tgttactgtg aaagaagttc gtctaagtcc
    35041 aactattgac aagggtgact ttgatacaaa acttcgtaat gcacgtaagt tccttgaaaa
    35101 aggaaataaa gttaaggtat ctattcgctt taagggtcgt atgattaccc ataaagagat
    35161 tggtgcaaaa gttttagccg agtttgctga agcaactcaa gatattgcca tcatcgaaca
    35221 acgtgctaaa atggatggac gtcaaatgtt catgcaattg gcgccagcga ctgacaaaaa
    35281 ataattgtca gaaagttaaa taaaggagaa aaaatcatgc caaaacaaaa aacacaccgc
    35341 gcatcagcta aacgtttcaa acgtacaggt tctggtggac ttaaacgttt ccgtgcttac
    35401 acttctcacc gtttccacgg aaaaactaag aaacaacgtc gtcatcttcg taaagcatct
    35461 atggtgcatt caggagatta caaacgtatc aaagcaatgc ttactcgctt gaaataatag
    35521 cttgactgta agtaaacaat tctaggaaat atttggagga aataaaacat ggcacgtgtt
    35581 aaaggtggcg ttgtatcacg caaacgtcgt aaacgtattc ttaaattagc aaaaggttac
    35641 tatggagcta aacacatctt attccgtact gcaaaagaac aagtaatgaa ctcttactac
    35701 tatgcatacc gtgaccgtcg tcagaaaaaa cgtgacttcc gcaaattgtg gattactcgt
    35761 atcaatgcgg cagctcgtat gaacggactt tcatactcac aattgatgca tggtttgaaa
    35821 ttggctgaga ttgaagttaa ccgtaaaatg cttgctgact tggctgttaa cgatgcagta
    35881 gctttcacag ctcttgcaga tgcagctaaa gcaaaacttg gtaaataaca actgatgaga
    35941 ctggaacagg attgtccagt ctttttaaaa ataaaggaga aagatatggc ttcaaaaatg
    36001 ctacacactt gcttacgagt agaaaatctt gaaaaatcaa tcgcatttta tcaagatgct
    36061 tttggtttta aagaattgcg tcgcagagat tttccagacc atgccttcac gattgtctat
    36121 ctaggtcttg agggtgatga ttatgagttg gagttgactt ataactacga tcacggtccg
    36181 tatgtggttg gtgatgggtt tgcccatatc gctctcagta cacctgatct tgaggcactt
    36241 catcaagaac acagtgcaaa aggctatgaa gtgactgagc caaatggtct accaggaact
    36301 acaccaaact attactttgt caaagaccct gatggatata aggtcgaagt cattcgtgaa
    36361 aaataatttc gtgcaagtta agtagaatat tcgttttcta cttgactttt tttagctgaa
    36421 agagtatact aataaaaatt caacctttaa ggggagtcca gagagactca caaggtgtca
    36481 gataaaagaa tagtgcaatt ttgtagagga gaccttttga gtgtgctctc ttgtgttgta
    36541 cgattttaac tgaggccttg cactagcaag gtcttttctt tatctggtcc ccttaaaatt
    36601 taaggaggaa aagttatgaa tctcacatgt aagaagcgtt tgggtgtcat tcggttggaa
    36661 accatgaagg tggttgcaca agaggaaatc gcgccagcaa tctttgaatt agtcctagaa
    36721 ggagaaatgg ttgaagccat gcgagcaggc caatttcttc atctgcgtgt accagacgat
    36781 gcccatctct tacgtcgtcc tatttcaatt tcgtctattg acaaggcaaa caagcagtgt
    36841 cacctcattt atcggattga gggagctggg actgcaattt tttcaacctt aagtcaggga
    36901 gacactcttg atgtgatggg gcctcaggga aatggttttg acttgtctga ccttgatgag
    36961 cagaatcagg ttctccttgt tggtggtggg attggtgttc cacccttgct tgaggtggcc
    37021 aaggaattgc atgaacgtgg agtgaaagta gtgacagtcc tcggttttgc taataaggat
    37081 gctgttattt tgaaaacgga attggctcag tatggtcatg tctttgtaac gacagatgat
    37141 ggttcttatg gcatcaaggg aaatgtttcc gttgttatca atgatttaga cagtcagttt
    37201 gatgctgttt actcgtgtgg ggctccagga atgatgaagt atatcaatca aacctttgat
    37261 gatcacccaa gagcctattt atctctggaa tctcgtatgg cttgtgggat gggagcttgc
    37321 tatgcctgtg ttctaaaagt accagaaaac gagacggtca gccaacgcgt ctgtgaagat
    37381 ggtcctgttt tccgcacagg aacagttgta ttataaggag aaaattatga ctacaaatcg
    37441 attacaagtt tctctacctg gtttggattt gaaaaatccg attattccag catcaggctg
    37501 ttttggcttt ggacaagagt atgccaagta ctatgattta gaccttttag gttctattat
    37561 gatcaaggcg acaacccttg aaccacgttt tgggaatcca actccaagag tggcagagac
    37621 gcctgctggt atgctcaatg caattggctt gcaaaatcct ggtttagagg ttgttttggc
    37681 tgaaaagcta ccttggctgg aaagagaata tccaaatctt cctattattg ccaatgtagc
    37741 tggtttttca aaacaagagt atgcagctgt ttctcatggg atttccaagg caactaatgt
    37801 aaaagctatc gagctcaata tttcttgtcc caatgttgac cactgtaatc atggactttt
    37861 gattggtcaa gatccagatt tggcttatga tgtggtgaaa gcagctgtgg aagcctcaga
    37921 agtgccagtt tatgtcaaat taaccccgag tgtgaccgat atcgttactg tcgcaaaagc
    37981 tgcagaagat gcgggagcaa gtggcttgac catgatcaat actctggttg gaatgcgctt
    38041 tgacctcaaa accagaaaac caatcttggc caatggaaca ggtggaatgt caggtccagc
    38101 agtctttcca gtagccctca aactcatccg ccaagtagcc caaacaacag acctgcctat
    38161 cattggaatg gggggagtgg attcgactga agctgcccta gaaatgtatc tggctggggc
    38221 atctgctatc ggagttggaa cagctaactt taccaatcct tatgcctgcc ctgacatcat
    38281 cgaaaattta ccaaaagtca tggataaata cggtattagc agtctggaag aactccgtca
    38341 ggaagtaaaa gagtctctga ggtaaactgc aatcaatctg ttcttgattt tttattagtt
    38401 tgtaatatga atttaggaga attttggtac aataaaataa ataagaacag aggaagaagg
    38461 ttaatgaaga aagtaagatt tattttttta gctctgctat ttttcttagc tagtccagag
    38521 ggtgcaatgg ctagtgatgg tacttggcaa ggaaaacagt atctgaaaga agatggcagt
    38581 caagcagcga atgagtgggt ttttgatact cattatcaat cttggttcta tataaaagca
    38641 gatgctaact atgctgaaaa tgaatggcta aagcaaggtg acgactattt ttacctcaaa
    38701 tctggtggct atatggccaa atcagaatgg gtagaagaca agggagcctt ttattatctt
    38761 gaccaagatg gaaagatgaa aagaaatgct tgggtaggaa cttcctatgt tggtgcaaca
    38821 ggtgccaaag taatagaaga ctgggtctat gattctcaat acgatgcttg gttttatatc
    38881 aaagcagatg gacagcacgc agagaaagaa tggctccaaa ttaaagggaa ggactattat
    38941 ttcaaatccg gtggttatct actgacaagt cagtggatta atcaagctta tgtgaatgct
    39001 agtggtgcca aagtacagca aggttggctt tttgacaaac aataccaatc ttggttttac
    39061 atcaaagaaa atggaaacta tgctgataaa gaatggattt tcgagaatgg tcactattat
    39121 tatctaaaat ccggtggcta catggcagcc aatgaatgga tttgggataa ggaatcttgg
    39181 ttttatctca aatttgatgg gaaaatagct gaaaaagaat gggtctacga ttctcatagt
    39241 caagcttggt actacttcaa atccggtggc tacatggcag ccaatgaatg gatttgggat
    39301 aaggaatctt ggttttacct caagtttgat ggcaaaatgg ctgaaaaaga atgggtttac
    39361 gattctcata gtcaagcctg gtactacttc aaatccggtg gttacatgac agccaatgaa
    39421 tggatttggg ataaggaatc ttggttttac ctcaaatctg atgggaaaat agctgaaaaa
    39481 gaatgggtct acgattctca tagtcaagct tggtactact tcaaatccgg tggttacatg
    39541 acagccaatg aatggatttg ggataaggaa tcttggtttt acctcaagtc tgatggcaaa
    39601 atggctgaaa aagaatgggt ctacgattct catagtcaag cctggtacta cttcaaatct
    39661 ggtggctaca tggcgaaaaa tgagacagta gatggttatc agcttggaag cgatggtaaa
    39721 tggcttggag gaaaagctac aaatgaaaat gctgcttact atcaagtagt gcctgttaca
    39781 gccaatgttt atgattcaga tggtgaaaag ctttcctata tatcgcaagg tagtgtcgta
    39841 tggctagata aggatagaaa aagtgatgac aagcgcttgg ctattactat ttctggtttg
    39901 tcaggctata tgaaaacaga agatttacaa gcgctagatg ctagtaagga ctttatccct
    39961 tattatgaga gtgatggcca ccgtttttat cactatgtgg ctcagaatgc tagtatccca
    40021 gtagcttctc atctttctga tatggaagta ggcaagaaat attattcggc agatggcctg
    40081 cattttgatg gttttaagct tgagaatccc ttccttttca aagatttaac agaggctaca
    40141 aactacagtg ctgaagaatt ggataaggta tttagtttgc taaacattaa caatagcctt
    40201 ttggagaaca agggcgctac ttttaaggaa gccgaagaac attaccatat caatgctctt
    40261 tatctccttg cccatagtgc cctagaaagt aactggggaa gaagtaaaat tgccaaagat
    40321 aagaataatt tctttggaat tacagcctat gatacgaccc cttacctttc tgctaagaca
    40381 tttgatgatg tggataaggg aattttaggt gcaaccaagt ggattaagga aaattatatc
    40441 gataggggaa gaactttcct tggaaacaag gcttctggta tgaatgtgga atatgcttca
    40501 gacccttatt ggggcgaaaa aattgctagt gtgatgatga aaatcaatga gaagctaggt
    40561 ggcaaagatt agtactataa gtgaatatga tttgagtgaa tagtaagtta aaaatcctga
    40621 tttcaagtaa aatcaggatt ttttcatgga tgcaattttt ttggagtctg gtgtgacgcg
    40681 gagggtcttt tgtcctgtgt aagtgacaaa gccgggtttt ccaccagttg gtttattgag
    40741 ttttttgact tcaatcatat ctacctgcac cagattcgac aggcgccctt gagagaagta
    40801 ggcagctaac tctgctgcgt ctgtcttgac tgcatcagat gggtcaagat ttcctgagat
    40861 gacaacatgg cttccaggaa tgtccttagc atggaaccaa agttcctcct tgcgggccat
    40921 tttaaaggtc aattcctcat tttgaagatt gtttcgtccg acatagatga tggttttgcc
    40981 atcgcttgct agatattgtt ctagtttttt gcgtttctgg attttctccc gttgtcttct
    41041 gcggataaaa cctgtttgaa tcaattcttc acggatttca gcgatttctt ccagtccagc
    41101 ttggttgagg acggtttcta cactttccag atagagaata gtggctttgg tttcttcaat
    41161 caaatcagtc aagtatttga cagcttcttt gagtttctga taccgtttaa aatagcgttg
    41221 ggcattctgg ttgggagtca gagccttatc aagcgcaatc atgataggtt ggttggtata
    41281 gtagttgtct aggataacct ggtcttggtc gttaggtact tggtggagga aggttgtcag
    41341 caattctcct ttttgacgaa attcttcagc gttgtctgtc tccagtaact ctttttcctg
    41401 ttttttgagt ttgtgtcggt ttttctgaag ttcattttca acacgacgaa tcagttcact
    41461 ggcctgctgt ttgacgcggt cgcgctcagc cttatcctta tagtaggtgt ccaacaaatc
    41521 agaaagattt gcaaaaggct ctcccacctg atttgcaaaa ggaactggac tgaaggaagt
    41581 ctcagtcaag catggcttgg tttcttgatt gaaaaaattt cggaaagcgg aaaatttttc
    41641 actaaccagt atcctttcca attcatttgc cgtatcgcgt cccagacctt gaaagatgct
    41701 ttgaagattt tttgctgtta gttcttgggt ttgcaggatt tcaaagagct tttcatcctt
    41761 gatagtaaaa ggattgagag attctgtact tggcggagcg atataggtcg atcctggaag
    41821 taaggtgcgg tagctatttt gtgaaaaacc gacgtgtttg ataacttcga ggattttatg
    41881 actgctttta tcgaccagta gaatattact gtgttttccc ataatttcaa taatcaaggt
    41941 agcctggata tggtctccaa tctcgttttt attggaaact gtaatttcca caatacggtc
    42001 attttccact tgctcaatcg actcaatcag ggccccctgc aaatactttc tcaaaaccat
    42061 gataaaggta gaaggttggg ctggattttc aaaagtcgtt tgggtcagct gaatgcgtcc
    42121 aaaaactgga tgggcagaaa ggagcaggcg atggctttgg cgattgctgc ggatttgcaa
    42181 gaccaactct tgttcaaaag gctgattgat tttctggatg cgaccattca ctaattcgct
    42241 tcgcaattcc tcaactatgt ggtgtaaaaa aaatccgtca aatgacatcg ttctctcctt
    42301 gtgattgtat tccatagtat tatatcaaaa aggtagaata aaatcatgga aatgtggtat
    42361 aataaagcca agtaaagaga aacgagaagc acatgtatat tgaaatggta gatgaaactg
    42421 gtcaagtttc aaaagaaatg ttgcaacaaa cccaagaaat tttggaattt gcagcccaaa
    42481 aattaggaaa agaagacaag gagatggcag tcacttttgt gaccaatgag cgtagtcatg
    42541 aacttaatct ggagtaccgt gacaccgacc gtccgacaga tgtcatcagc cttgagtata
    42601 aaccagaatt ggaaattgcc tttgacgaag aggatttgct tgaaaatcca gaattggcag
    42661 agatgatgtc tgagtttgat gcctatattg gggaattgtt catctctatc gataaggctc
    42721 atgagcaggc cgaagaatat ggtcacagct ttgagcgtga gatgggcttc ttggcagtac
    42781 acggcttttt acatattaac ggctatgatc actatactcc ggaagaagaa gcggagatgt
    42841 tcggtttaca agaagaaatt ttgacagcct atggactcac aagacaataa acgaaaatgg
    42901 aaaaatcgtg acctgatatc cagtttagaa tttgccatca cagggatttt tactgctatc
    42961 aaggaagaac gcaatatgcg aaaacatgca gtgacggctc tagtggtcat ccttgcaggt
    43021 tttggttttc aggtgtcacg aatcgaatgg ctctttctcc tattgagcat tttcttggta
    43081 gtagcctttg agattatcaa ctctgctatt gaaaatgtgg tggatttggc cagtcactat
    43141 cacttttcca tgctggctaa aaatgccaag gatatggcgg ctggcgcggt attagtggtt
    43201 tctctttttg cagccttaac aggcgcattg atttttctcc cacgaatctg ggatttatta
    43261 ttttaaacag taagaggaaa ttatgacttt taaatcaggc tttgtagcca ttttaggacg
    43321 tcccaatgtt gggaagtcaa cctttttaaa tcacgttatg gggcaaaaga ttgccatcat
    43381 gagtgacaag gcgcagacaa cgcgcaataa aatcatggga atttacacga ctgataagga
    43441 gcaaattgtc tttatcgaca caccagggat tcacaaacct aaaacagctc tcggagattt
    43501 catggttgag tctgcctaca gtacccttcg cgaagtggac actgttcttt tcatggtgcc
    43561 tgctgatgaa gcgcgtggta agggggacga tatgattatt gagcgtctca aggctgccaa
    43621 ggttcctgtg attttggtgg tgaataaaat cgataaggtt catccagacc agctcttgtc
    43681 tcagattgat gacttccgta atcaaatgga ctttaaggaa attgttccaa tctcagccct
    43741 tcagggaaat aacgtgtctc gtctagtgga tattttgagt gaaaatctgg atgaaggttt
    43801 ccaatatttc ccgtctgatc aaatcacaga ccatccagaa cgtttcttgg tttcagaaat
    43861 ggttcgcgag aaagtcttgc atctaactcg tgaagagatt ccgcattctg tagcagtagt
    43921 tgttgactct atgaaacgag acgaagagac agacaaggtt cacatccgtg caaccatcat
    43981 ggtcgagcgc gatagccaaa aagggattat catcggtaaa ggtggcgcta tgcttaagaa
    44041 aatcggtagc atggcccgtc gtgatatcga actcatgcta ggagacaagg tcttcctaga
    44101 aacctgggtc aaggtcaaga aaaactggcg cgataaaaag ctagatttgg ctgactttgg
    44161 ctataatgaa agagaatact aagtagaggt aggctcatgc ctgcttcttg tttttacaga
    44221 aggaggactt atgcctgaat tacctgaggt tgaaaccgtt tgtcgtggct tagaaaaatt
    44281 gattatagga aagaagattt cgagtataga aattcgctac cccaagatga ttaagacgga
    44341 tttggaagag tttcaaaggg aattgcctag tcagattatc gagtcaatgg gacgtcgtgg
    44401 aaaatatttg cttttttatc tgacagacaa ggtcttgatt tcccatttgc ggatggaggg
    44461 caagtatttt tactatccag accaaggacc tgaacgcaag catgcccatg ttttctttca
    44521 ttttgaagat ggtggcacgc ttgtttatga ggatgttcgc aagtttggaa ccatggaact
    44581 cttggtgcct gaccttttag acgcctactt tatttctaaa aaattaggtc ctgaaccaag
    44641 cgaacaagac tttgatttac aggtctttca atctgccctt gccaagtcca aaaagcctat
    44701 caaatcccat ctcctagacc agaccttggt agctggactt ggcaatatct atgtggatga
    44761 ggttctctgg cgagctcagg ttcatccagc tagatcttcc cagactttga cagcagaaga
    44821 agcgacagct attcatgacc aaaccattgc tgttttgagc caggctgttg aaaaaggcgg
    44881 ttccaccatt cggacctata ccaatgcctt tggggaagat ggaagcatgc aggattttca
    44941 tcaggtctat gataagactg gtcaaggatg tgtacgctgt ggtaccatca ttgagaaaat
    45001 tcaactaggt ggacgtggaa cccacttttg tccaaactgt caaaggaggg actgatggga
    45061 aaaatcatcg gaatcactgg gggaattgcc tctggtaagt caactgtgac aaattttcta
    45121 agacagcaag gctttcaagt agtggatgcc gacgcagtcg tccaccaact acagaaacct
    45181 ggtggtcgtc tgtttgaggc tctagtacag cactttgggc aagaaatcat tcttgaaaac
    45241 ggagaactca atcgccctct cctagctagt ctcatctttt caaatcctga tgaacgagaa
    45301 tggtctaagc aaattcaagg ggagattatc cgtgaggaac tggctacttt gagagaacag
    45361 ttggctcaga cagaagagat tttcttcatg gatattcccc tactttttga gcaggactac
    45421 agcgattggt ttgctgagac ttggttggtc tatgtggacc gagatgccca agtggaacgc
    45481 ttaatgaaaa gggaccagtt gtccaaagat gaagctgagt ctcgtctggc agcccagtgg
    45541 cctttagaaa aaaagaaaga tttggccagc caggttcttg ataataatgg caatcagaac
    45601 cagcttctta atcaagtgca tatccttctt gagggaggta ggcaagatga cagagattaa
    45661 ctggaaggat aatctgcgca ttgcctggtt tgataatttt ctgacaggag ccagtatttc
    45721 tttggttgta ccttttatgc ccatcttcgt ggaaaatcta ggtgtaggga gtcagcaagt
    45781 cgctttttat gcaggcttag caatttctgt ctctgctatt tccgcggcgc tcttttctcc
    45841 tatttggggt attcttgctg acaaatacgg ccgaaaaccc atgatgattc gggcaggtct
    45901 tgctatgact atcactatgg gaggcttggc ctttgtccca aatatctatt ggttaatctt
    45961 tcttcgttta ctaaacggtg tatttgcagg ttttgttcct aatgcaacgg cactgatagc
    46021 cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt actttgtcta caggcgtagt
    46081 tgcaggtact ctaactggtc cctttattgg tggctttatc gcagaattat ttggcattcg
    46141 tacagttttc ttactggttg gtagttttct atttttagct gctattttga ctatttgctt
    46201 tatcaaggaa gattttcaac cagtagccaa ggaaaaggct attccaacaa aggaattgtt
    46261 tacttcagtt aaatatccct atcttttgct caatctcttt ttaaccagtt ttgtcatcca
    46321 attttcagct caatcgattg gccctatttt ggctctttat gtacgcgact tagggcagac
    46381 agagaatctt ctttttgtct ctggtttgat tgtgtccagt atgggctttt ccagcatgat
    46441 gagtgcagga gtcatgggca agctaggtga caaggtgggc aatcatcgtc tcttggttgt
    46501 cgcccagttt tattcagtca tcatctatct cctctgtgcc aatgcctcta gcccccttca
    46561 actaggactc tatcgtttcc tctttggatt gggaaccggt gccttgattc ccggggttaa
    46621 tgccctactc agcaaaatga ctcccaaagc cggcatttcg agggtctttg ccttcaatca
    46681 ggtattcttt tatctgggag gtgttgttgg tcccatggca ggttctgcag tagcaggtca
    46741 atttggctac catgctgtct tttatgcgac aagcctttgt gttgccttta gttgtctctt
    46801 taacctgatt caatttcgaa cattattaaa agtaaaggaa atctagtgcg agtaaaaatt
    46861 aatctcaaat gctcctcttg tggcagtatc aattacctaa ccagtaaaaa ttcaaaaacc
    46921 catccagaca agattgaggt tttaaagtat tgtcccaagg aaagaaaagt aaccctacat
    46981 cttgaatcta agtagatttt atggtaaaat aatagggatt ttaaggagtt tgatatgtat
    47041 aacctattat taaccatttt attagtatta tctgttgtga ttgtgattgc aattttcatg
    47101 caaccaacca aaaaccaatc cagcaatgta tttgatgcca gttcaggtga tttgtttgaa
    47161 cgcagtaaag ctcgcggttt tgaagctgta atgcagcgtt tgacagggat tttagtcttt
    47221 ttctggctag ccattgcctt agcattgacg gtattatcaa gtagataaga aaataatggg
    47281 caagactagg tctttgcctc tttttatttt taaaggatgt ttgagaaggt tttacagtaa
    47341 aagaaaatta aaaaatctag aaagaaaata tgaaagatag aataaaagaa tatttacaag
    47401 acaagggaaa ggtgactgtt aatgatttgg ctcaggcttt gggaaaagac agttccaagg
    47461 attttcgtga gttgattaaa accttgtcct taatggaaag aaagcaccag attcgctttg
    47521 aagaagatgg tagtctgaca ttagaaatta agaaaaaaca tgagattacc ctcaagggga
    47581 tttttcatgc ccataaaaat ggctttggct ttgttagtct ggaaggcgag gaggacgacc
    47641 tttttgtagg gaaaaatgat gtcaactatg ctattgatgg tgataccgtc gaggtagtga
    47701 ttaagaaagt cgctgaccgc aataagggaa cagcagcaga agccaaaatt attgatatcc
    47761 tagaacacag tttgacaaca gttgtcgggc aaatcgttct ggatcaggaa aagcctaagt
    47821 atgctggcta tattcgttca aaaaatcaga aaatcagtca accgatttat gttaagaaac
    47881 cagccctaaa attagaagga acagaagttc tcaaagtctt tatcgataaa tacccaagca
    47941 agaaacatga tttctttgtc gcgagtgttc tcgatgtagt ggggcactca acggatgtcg
    48001 gaattgatgt tcttgaggtc ttggaatcaa tggacattgt atctgagttt ccagaagctg
    48061 ttgtcaagga agcagaaagt gtgcctgatg ctccgtctca aaaggatatg gaaggtcgtt
    48121 tggatctaag agatgaaatt acctttacca ttgacggtgc ggatgccaag gacttggacg
    48181 atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga gcttggggtt cacatcgcag
    48241 atgtttccta ttatgtgacc gagggttctg cccttgacaa ggaagccctt aaccgtgcga
    48301 cttctgttta cgtgacagac cgagtggtgc caatgcttcc agaacgacta tcaaatggca
    48361 tctgctctct caatccccaa gttgaccgcc tgacccagtc tgctattatg gagattgata
    48421 aacatggtcg tgtggtcaac tataccatta cacaaacagt tatcaagacc agttttcgta
    48481 tgacctatag cgatgtcaat gatatcctag ctggcgatga agaaaagaga aaagaatacc
    48541 ataaaattgt accaagtatc gaactcatgg ccaagcttca tgaaacttta gaaaacatgc
    48601 gtgtgaaacg tggagctctc aattttgata ccaatgaagc gaagatttta gtggataaac
    48661 aaggtaagcc tgttgatatc gttcttcggc agcgtggcat tgccgagcgg atgattgagt
    48721 cttttatgtt gatggctaat gaaacagttg ccgaacattt cagcaagttg gatttgcctt
    48781 ttatctaccg aattcacgag gagcctaagg ctgaaaaggt tcagaagttt attgattatg
    48841 cttcgagttt tggcttgcgc atttatggga ctgccagtga gattagccag gaggcacttc
    48901 aagacatcat gcgtgctgtt gagggagaac cttatgcaga tgtattgtcc atgatgcttc
    48961 ttcgctctat gcagcaggct cgttattcgg agcacaatca cggccactat ggactagctg
    49021 ctgactatta tactcacttt accagtccaa ttcgtcgtta tccagacctt cttgttcacc
    49081 gtatgattcg ggattacggc tgttctaagg aaatagcaga gcattttgaa caagtgattc
    49141 cagagattgc gacccagtct tccaaccgtg aacgtcgtgc catagaagct gagcgtgaag
    49201 tcgaagccat gaaaaaggct gagtatatgg aagaatacgt gggtgaagag tatgatgcag
    49261 ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt gccaaacaca gttgaaggct
    49321 tgattcacat cactaatcta cctgaatttt atcatttcaa tgagcgtgat ttgactcttc
    49381 gtggagaaaa atcaggtatc actttccgag tgggtcagca gatccgtatc cgtgttgaaa
    49441 gagcggataa aatgactgga gagattgatt tttcattcgt acctagtgag tttgatgtga
    49501 ttgaaaaagg cttgaaacag tctagtcata gtggcagagg gcgtggttca aatcgtcgtt
    49561 cggataagaa ggaagacaag agaaaatcag gacgctcaaa tgataagcgt aagtattcac
    49621 aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa ggaagtagct aagaaaggag
    49681 ccaagcatgg caaagggcga gggaaaggtc gtcgcacaca ataaaaaggc acgccacgac
    49741 tatacaatcg tagatacgct agaggcaggg atggtcctga ctggaactga aatcaagagt
    49801 gtacgagctg ctcgaattaa tctcaaggat ggctttgctc aagtgaaaaa tggagaagtt
    49861 tggctgagca atgttcatat cgcgccttac gaagagggca atatctggaa ccaggaacca
    49921 gaacgtcgtc gtaaactcct gctccataaa aagcaaattc aaaaattgga acaagagacc
    49981 aaagggacag gaatgacctt agttcccctt aaggtctata taaaagatgg ctacgctaag
    50041 cttcttttag gacttgccaa agggaagcat gactatgaca aacgggagtc tatcaaacgt
    50101 cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg ttaatcagcg ataaaaagag
    50161 gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc ctttgtggaa taaacaaaca
    50221 atgcctgaag ctgttcagca aaagcacaat acaaaagttg ggacttgggg gaaaattact
    50281 gtcttgaagg gagctctcaa gtttattgaa ttgacagaag aaggggaagt tctagctgaa
    50341 cacctctttg aagcaggggc agacaatcca atggcccaac ctcaagcctg gcaccgagtg
    50401 gaagctgcca cagatgatgt ggaatggtac ttggaatttt attgtaaacc tgaggattat
    50461 tttgctaaaa aatacaatac caatcctgtt cattcagagg tcctagaggc catgcagaca
    50521 gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg ggcgtaattc tctttttcta
    50581 gcccagcaag attttgatgt gacggctgta gatcaaaatg gactagctct tgaaatcttg
    50641 caaagcattg tggagcagga agatttggac atgcctgttg gcctttacga tatcaattca
    50701 gctagcattg aacaagaata tgattttatc gtttcaacag ttgttctcat gtttctacaa
    50761 gcggaccgca ttccagctat tattcaaaat atgcaggaga aaaccagtgt tggtggttac
    50821 aaccttatcg tttgtgccat ggacacggag gattatcctt gctcggttaa cttcccattc
    50881 acctttaaag aaggagaact ggcagactat tacaaggatt gggaattggt taagtacaat
    50941 gaaaatccag gccatttgca ccgtcgcgat gagaatggca atcgtattca actacgcttt
    51001 gcgaccttac tagctaagaa aatcaagtaa acatacatga agattaggaa ttttcctgat
    51061 cttttttctt ttttacgaat gatatagaaa aggagggaat tcatgtttgt tgcgagagat
    51121 gctaggggag aattggtaaa tgtgttagag gataaacttg agaagcaagc atacacctgc
    51181 ccagcttgtg gaggccagat ccatttgcgt caaggaccaa gtgtacggac gcattttgcc
    51241 cataaatcct taaaagactg tgattttttc tttgaaaatg aaagtccaga acacctggcc
    51301 aataaggaat ccctctatca ctggttgaaa aaagagacaa aggttcaatt agagtacccg
    51361 ctttcagaac ttaaacagat tgcggatgta tttgtaaatg gcaatctagc tctagaagtt
    51421 cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa gtgagggcta tcgtagtcag
    51481 ggttaccaag tactgtggtt gctgggtcaa aaactgtggc tcaaggagcg tttgactcgt
    51541 ctacagcaag gttttcttta tttcagtcaa aacatgggct tttatgtttg ggaattagac
    51601 aaggaaaaac aagttttaag actcaaatac ctgatttacc aggatctccg cggtaaactc
    51661 cattatcaaa tcaaggaatt ttcctatggt caaggtagtt tattggaaat attgcgtctt
    51721 ccctataaga aacaaaaaat atctcatttt acagtttctg aggacaagga catctgtcgc
    51781 tatatccggc aacaacttta ttatcaaaat ctcttttgga tgaaagaaca agcagaagcc
    51841 tatcaaaagg gagaaaatat cctgacttat ggactgaaag aatggtatcc acaaattcga
    51901 ccaatagtgg gcaaattttt ccagattgaa caagacttga ctagctatta tcagcacttt
    51961 tatacctatt accaaaaaaa tcctcaaaat gattggcaaa agctttatcc accagccttt
    52021 tatcagcaat atttcttgaa aaatatggta gaatagaaag gatggaggaa tctaatggta
    52081 ttacaaagaa atgaaataaa tgaaaaagat acatgggatc tatcaacgat ctacccaact
    52141 gaccaggctt gggaagaagc cttaaaagat ttaacagaac aattggagac agtagcccag
    52201 tatgaaggcc atctcttgga tagtgcggat aacctactag aaatcactga attttctctt
    52261 gaaatggaac gccagatgga gaagctttac gtttatgctc atatgaagaa tgaccaggat
    52321 acacgtgaag ctaagtatca agagtactat gccaaggcca tgacactcta cagccagtta
    52381 gaccaagcct tttcattcta tgagcctgaa tttatggaga ttagcgaaaa gcagtatgct
    52441 gactttttag aagctcaacc aaagctgcag gtttatcaac actattttga caagctcttg
    52501 caaggcaagg atcacgttct ttcacaacgt gaagaagaat tattggctgg agctggagaa
    52561 atctttggtt cagcaagtga aaccttcgct atcttggaca atgcggatat tgtgttccct
    52621 tatgtactag atgatgatgg taaagaagtt caactatctc atgggactta cacacgtttg
    52681 atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc aagctcttta tgcgacttac
    52741 gaacaattcc aacacaccta tgccaaaacc ttgcaaacca atgttaaggt gcaaaattac
    52801 cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag ccctcgcagc gaattttgtt
    52861 ccagaaagtg tttatgacaa tttggtagca gcagttcgca agcatttgcc actcttacat
    52921 cgctatcttg agcttcgttc aaaaatcttg gggatttcag atctcaagat gtacgatgtc
    52981 tacacaccgc tttcatctgt tgaatacagt tttacctacc aagaagcctt gaaaaaagca
    53041 gaagatgctt tggcagtctt gggtgaggat tacttgagcc gtgtcaaacg tgccttcagc
    53101 gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt caggtgccta ctctggtggt
    53161 tcttacgata ccaatgcctt tatgcttctc aactggcagg acaatctgga caatctcttt
    53221 actcttattc atgaaacagg tcacagtatg cattcaagct atactcgtga aactcagcct
    53281 tatgtttacg gagattactc tatctttttg gctgagattg cctcaactac caatgaaaat
    53341 atcttgacgg agaaattatt ggaagaagtg gaagacgacg caacacgctt tgctattctc
    53401 aataatttcc tagatggttt ccgtggaaca gttttccgcc aaactcaatt tgctgagttt
    53461 gaacacgcca ttcaccaagc agatcaaaat ggggaggtct tgacaagcga tttcctaaat
    53521 aaactctacg cagacttgaa ccaagagtat tatggtttga gtaaggaaga caatcctgaa
    53581 atccaatacg agtgggctcg cattccacac ttctactata actactatgt atatcaatat
    53641 tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa ttgtccatgg tagtcaagaa
    53701 gaccgtgacc gctatatcga ctacctcaag gcaggtaagt cggactatcc acttaatgtc
    53761 atgagaaaag ctggtgttga tatggagaag gaagactacc tcaacgatgc ctttgcagtc
    53821 tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa aattaggatt ggcataaaat
    53881 ggttgaatcg tatagtaaga atgctaacca taacatgcgt cgtcctgtcg tcaaagaaga
    53941 aattgtagac ttgatgcgtc agcgtcaaaa gcaagtcaca ggtttcttga aagaattgga
    54001 agactttgcc cgcaaggaaa atattcctat tattccccat gaaacggttg cttatttccg
    54061 ttttcttatg gaaaccatgc agcctaaaaa tattctggaa attgggacgg ctatcggttt
    54121 ttcagctctc ttgatggctg aacatgcgcc aaatgctaag attacaacta ttgatcgtaa
    54181 tccagaaatg attggttttg ccaaggaaaa ttttgcccag tttgacagtc gcaagcaaat
    54241 cactctccta gagggagatg cggtggatgt cttatctaca ctgacagagt cttatgattt
    54301 cgtctttatg gattctgcca agtctaaata catcgtcttt ctgccagaaa ttctcaaaca
    54361 tttggaagtt ggtggtgtgg ttgtcttgga tgatattttc caaggcggtg atgttgccaa
    54421 ggacattatg gaagtccgtc gaggtcagcg aaccatctat cgaggccttc aaagactatt
    54481 tgacgcaacc ttagacaatt cagaactcac cgcaacatta gtgcctttag gagatggtat
    54541 tctcatgctt cgtaaaaatg tagcagatgt tcaattgcct gacagcgaat gattttcaga
    54601 aaaatttaag aaaaaatagt aaaatagata gagtaacact tatctcaaag gagtagacat
    54661 gaagaaaaaa ttattggcag gtgccatcac actattatca gtagcaactt tagcagcttg
    54721 ttcgaaaggg tcagaaggag cagaccttat cagcatgaaa ggggatgtca tcacagaaca
    54781 tcaattttat gagcaagtga aaaacaaccc ttcagcccaa caagtcttgt taaatatgac
    54841 catccaaaaa gtttttgaaa aacaatatgg ctcagagctt gatgataaag aggttgatga
    54901 tactattgcc gaagaaaaaa aacaatatgg cgaaaactac caacgtgtct tgtcacaagc
    54961 aggtatgact cttgaaacac gtaaagctca aattcgtaca agtaaattag ttgagttggc
    55021 agttaagaag gtagcagaag ctgaattgac agatgaagcc tataagaaag cctttgatga
    55081 gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat aatgaagata aggccaaaga
    55141 agttctcgaa aaagccaagg cagaaggtgc tgattttgct caattagcca aagataattc
    55201 aactgatgaa aaaacaaaag aaaatggtgg agaaattacc tttgattctg cttcaacaga
    55261 agtacctgag caagtcaaaa aagccgcttt cgctttagat gtggatggtg tttctgatgt
    55321 gattacagca actggcacac aagcctacag tagccaatat tacattgtaa aactcactaa
    55381 gaaaacagaa aaatcatcta atattgatga ctacaaagaa aaattaaaaa ctgttatctt
    55441 gactcaaaaa caaaatgatt caacatttgt tcaaagcatt atcggaaaag aattgcaagc
    55501 agccaatatc aaggttaagg accaagcctt ccaaaatatc tttacccaat atatcggtgg
    55561 tggagattca agctcaagta gtagtacatc aaacgaatag tccaaatcaa tgaatcaggg
    55621 aaaaaactcg acttcaggaa aaaatgaagc aaacattccc acaataaaac gcgtagtaca
    55681 aggtttgtac tgacccccaa aagttagaca aataatttat ccgaaggatt tagttctgta
    55741 ttgcacaggg ctaagtcctt ttagttttac cttaattctc ttgttgttgt aataatcaat
    55801 atagtctata atggcttgtt ccaattgatt aagtgattta aatgttttct catagccata
    55861 aaacatttcg gattttaaaa tgccaaagaa agattccatc ctaccgttgt cttggctgtt
    55921 tcctttgcgt gacatagatg cttgaattcc cttactctct aggaagcgat gataagaatc
    55981 gtgttggtat tgccagcctt ggtcactatg gagaatcgta ttctcgtagt gcttctcttt
    56041 gaatgcctgt tccaacatta acgatcaatc aatttaatca t
//
LOCUS       DAVKZI010000009        52279 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKZI010000009 DAVKZI010000000
VERSION     DAVKZI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.009"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            161..2794
                     /gene="polA"
                     /locus_tag="VXB18_000645"
     CDS             161..2794
                     /gene="polA"
                     /locus_tag="VXB18_000645"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0381885.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2879..3316
                     /locus_tag="VXB18_000646"
     CDS             2879..3316
                     /locus_tag="VXB18_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0381886.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKTAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            3357..3434
                     /locus_tag="VXB18_000647"
                     /pseudo
     CDS             3357..3434
                     /locus_tag="VXB18_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3589..4599)
                     /locus_tag="VXB18_000648"
     CDS             complement(3589..4599)
                     /locus_tag="VXB18_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0381887.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSHKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            4748..5917
                     /locus_tag="VXB18_000649"
     CDS             4748..5917
                     /locus_tag="VXB18_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0381888.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5914..6684
                     /gene="recO"
                     /locus_tag="VXB18_000650"
     CDS             5914..6684
                     /gene="recO"
                     /locus_tag="VXB18_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0381889.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6681..7673
                     /gene="plsX"
                     /locus_tag="VXB18_000651"
     CDS             6681..7673
                     /gene="plsX"
                     /locus_tag="VXB18_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0381890.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            7679..7912
                     /locus_tag="VXB18_000652"
     CDS             7679..7912
                     /locus_tag="VXB18_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0381891.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            7958..8248
                     /locus_tag="VXB18_000653"
                     /pseudo
     CDS             7958..8248
                     /locus_tag="VXB18_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8451..8681
                     /gene="blpU"
                     /locus_tag="VXB18_000654"
     CDS             8451..8681
                     /gene="blpU"
                     /locus_tag="VXB18_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0381892.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGVARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            9396..11549
                     /locus_tag="VXB18_000655"
     CDS             9396..11549
                     /locus_tag="VXB18_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0381893.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKM
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            11562..12911
                     /locus_tag="VXB18_000656"
     CDS             11562..12911
                     /locus_tag="VXB18_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0381894.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            13081..13788
                     /locus_tag="VXB18_000657"
     CDS             13081..13788
                     /locus_tag="VXB18_000657"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0381895.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFTEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            13990..17715
                     /locus_tag="VXB18_000658"
     CDS             13990..17715
                     /locus_tag="VXB18_000658"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0381896.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNISE
                     ANILFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTVEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            17808..19250
                     /locus_tag="VXB18_000659"
     CDS             17808..19250
                     /locus_tag="VXB18_000659"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0381897.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            19287..20309
                     /locus_tag="VXB18_000660"
     CDS             19287..20309
                     /locus_tag="VXB18_000660"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0381898.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            20306..20851
                     /gene="purN"
                     /locus_tag="VXB18_000661"
     CDS             20306..20851
                     /gene="purN"
                     /locus_tag="VXB18_000661"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0381899.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            20935..21444
                     /locus_tag="VXB18_000662"
     CDS             20935..21444
                     /locus_tag="VXB18_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0381900.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            21469..23016
                     /gene="purH"
                     /locus_tag="VXB18_000663"
     CDS             21469..23016
                     /gene="purH"
                     /locus_tag="VXB18_000663"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0381901.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            23138..24400
                     /gene="purD"
                     /locus_tag="VXB18_000664"
     CDS             23138..24400
                     /gene="purD"
                     /locus_tag="VXB18_000664"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0381902.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            24803..25291
                     /gene="purE"
                     /locus_tag="VXB18_000665"
     CDS             24803..25291
                     /gene="purE"
                     /locus_tag="VXB18_000665"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0381903.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            25278..26369
                     /gene="purK"
                     /locus_tag="VXB18_000666"
     CDS             25278..26369
                     /gene="purK"
                     /locus_tag="VXB18_000666"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0381904.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            26379..26606
                     /locus_tag="VXB18_000667"
     CDS             26379..26606
                     /locus_tag="VXB18_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0381905.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            26669..27967
                     /gene="purB"
                     /locus_tag="VXB18_000668"
     CDS             26669..27967
                     /gene="purB"
                     /locus_tag="VXB18_000668"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0381906.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(28022..31960)
                     /gene="strH"
                     /locus_tag="VXB18_000669"
     CDS             complement(28022..31960)
                     /gene="strH"
                     /locus_tag="VXB18_000669"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0381907.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(32275..32991)
                     /locus_tag="VXB18_000670"
     CDS             complement(32275..32991)
                     /locus_tag="VXB18_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0381908.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            33339..35126
                     /locus_tag="VXB18_000671"
     CDS             33339..35126
                     /locus_tag="VXB18_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0381909.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPTYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            35123..35599
                     /locus_tag="VXB18_000672"
     CDS             35123..35599
                     /locus_tag="VXB18_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0381910.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            35627..36532
                     /locus_tag="VXB18_000673"
     CDS             35627..36532
                     /locus_tag="VXB18_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0381911.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            36519..37334
                     /locus_tag="VXB18_000674"
     CDS             36519..37334
                     /locus_tag="VXB18_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0381912.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            37341..37745
                     /locus_tag="VXB18_000675"
     CDS             37341..37745
                     /locus_tag="VXB18_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0381913.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            37998..39164
                     /locus_tag="VXB18_000676"
     CDS             37998..39164
                     /locus_tag="VXB18_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0381914.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            39280..40317
                     /locus_tag="VXB18_000677"
     CDS             39280..40317
                     /locus_tag="VXB18_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0381915.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            40525..41379
                     /locus_tag="VXB18_000678"
     CDS             40525..41379
                     /locus_tag="VXB18_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0381916.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKRLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            41516..41773
                     /locus_tag="VXB18_000679"
     CDS             41516..41773
                     /locus_tag="VXB18_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0381917.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(41815..42177)
                     /locus_tag="VXB18_000680"
     CDS             complement(41815..42177)
                     /locus_tag="VXB18_000680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381918.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKSNFWGSVHSTPDTMR
                     FFNFKDFLQLLLTHIKLF"
     gene            complement(42231..42527)
                     /locus_tag="VXB18_000681"
     CDS             complement(42231..42527)
                     /locus_tag="VXB18_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0381919.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(42517..42678)
                     /locus_tag="VXB18_000682"
     CDS             complement(42517..42678)
                     /locus_tag="VXB18_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0381920.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            42748..43512
                     /locus_tag="VXB18_000683"
     CDS             42748..43512
                     /locus_tag="VXB18_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0381921.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(43752..43904)
                     /locus_tag="VXB18_000684"
     CDS             complement(43752..43904)
                     /locus_tag="VXB18_000684"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381922.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            44122..45501
                     /locus_tag="VXB18_000685"
     CDS             44122..45501
                     /locus_tag="VXB18_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0381923.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            45515..46180
                     /locus_tag="VXB18_000686"
     CDS             45515..46180
                     /locus_tag="VXB18_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0381924.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            46294..46389
                     /locus_tag="VXB18_000687"
                     /pseudo
     CDS             46294..46389
                     /locus_tag="VXB18_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            46580..47119
                     /locus_tag="VXB18_000688"
     CDS             46580..47119
                     /locus_tag="VXB18_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0381925.1"
                     /translation="MKLLSIAIPSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            47186..47596
                     /locus_tag="VXB18_000689"
     CDS             47186..47596
                     /locus_tag="VXB18_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0381926.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTTEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            47712..49373
                     /locus_tag="VXB18_000690"
     CDS             47712..49373
                     /locus_tag="VXB18_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEV0381927.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQLALD
                     GNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETS
                     DTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDT
                     MMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
     gene            49540..50238
                     /locus_tag="VXB18_000691"
     CDS             49540..50238
                     /locus_tag="VXB18_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0381928.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            50235..51287
                     /locus_tag="VXB18_000692"
     CDS             50235..51287
                     /locus_tag="VXB18_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0381929.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHTKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQMETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            51482..52093
                     /gene="rpsD"
                     /locus_tag="VXB18_000693"
     CDS             51482..52093
                     /gene="rpsD"
                     /locus_tag="VXB18_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0381930.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
BASE COUNT        14650 a        10024 c        12373 g        15232 t
ORIGIN      
        1 gtgtactatt atagattcaa tatactatgt tatagcacat ttttaaatct aggtttacta
       61 aattctctgg ctctatctat ttattcggaa aaagtttgaa aaatacttgc tctagctctt
      121 cccaatggta ttttttgatt ctttccttta taatgggtgt atggataaga aaaaattatt
      181 attgattgat gggtcttctg tagcttttcg ggcgtttttt gcgctgtatc agcagttgga
      241 ccgttttaag aatgcggctg gtttgcatac caatgcgatt tatggtttcc agttgatgtt
      301 gagtcatttg ttggagcggg ttgagccgag tcatattttg gtggcttttg atgcgggaaa
      361 gacgaccttc cggacagaga tgtatgcgga ctataagggt ggtcgggcca agactcctga
      421 tgagtttcgt gagcaatttc ctttcattcg tgagttgctg gatcatatgg ggattcgtca
      481 ctatgagctg gctcagtatg aggcggatga catcattggg acgctggata agctagcaga
      541 gcaggatggt tttgatatta ccattgtcag tggggacaag gatttgattc agctgacgga
      601 tgagcatacg gtggttgaaa tttccaagaa aggtgtggct gagtttgagg cctttacgcc
      661 agattacctc atggaagaaa tgggcctcac accagctcag tttatcgatc tcaaggcgct
      721 catgggtgat aagtcggata atatccctgg ggtgaccaaa gtcggtgaaa agacgggtat
      781 taagctcttg ctggagcatg gttcgcttga ggggatttat gaaaatattg atggaatgaa
      841 gacttctaag atgaaggaaa atctcatcaa tgacaaggaa caggcctttt tgtctaaaac
      901 actagcgacc attgatacca aggcaccgat tgcgattggt ttagaggact tggtctatag
      961 tggtccagat gttgaaaatc ttgggaaatt ctacgatgag atgggcttca aacagctcaa
     1021 gcaggcttta aatgtgtcgt cagctgatgt ggctgagggt ttggatttta ctattgttga
     1081 ccaaatcagt caagatatgc tgagtgaaga gtctatcttc cactttgagc tttttggtga
     1141 gaattaccat acggataatt tggttggatt tgcctggtct tgtggggata agctctatgc
     1201 cacagacaag cttgagctgt tgcaagaccc gattttcaag gatttcttag aaaaaacatc
     1261 tctgagagtt tatgacttta agaaggttaa agttcttttg caacgttttg gtgtggattt
     1321 gcaggcgcct gcttttgaca tccgtttggc taaatacctc ctttcgactg tggaggacaa
     1381 tgaaattgcg accatcgcta gtctttatgg tcagacttac ttggttgatg atgaaacttt
     1441 ctacggtaag ggtgttaaaa aggccattcc tgaacgtgag aaattcttgg aacacttagc
     1501 ttgtaaactt gctgttttgg tagaaacaga gcctatttta cttgaaaaac tcagcgaaaa
     1561 tgggcaatta gagcttcttt atgatatgga gcaacctctg gcttttgttc ttgccaagat
     1621 ggaaattgct gggattgtgg tcaagaaaga gaccttgctt gagatgcagg ctgaaaatga
     1681 gcttgtcatt gaaaaactga ctcaagagat ttacgagctg gctggtgagg agtttaatgt
     1741 caactcgcct aagcagttgg gcgtgcttct ctttgagaaa ttgggacttc ctctagaata
     1801 cactaagaaa accaagacag gttattcgac agcagtggat gtgttggagc gtctcgctcc
     1861 tattgctccg attgttaaga aaatcctgga ttaccgtcaa attgctaaga ttcaatctac
     1921 ttatgtaatt ggcttgcagg actggatttt ggctgatgga aagattcata ctcgctatat
     1981 gcaggatttg acccagaccg ggcgtttgtc tagtgtggat ccaaacttgc aaaatattcc
     2041 tgcccgattg gaacaagggc gcttgattcg gaaggctttt gtgccagagt gggaggatag
     2101 tgtgctactc agctctgact attcacagat tgaattgcgc gttttggcgc atatttctaa
     2161 ggatgagcac ttgattaagg ccttccaaga gggggcagat atccatactt cgacagccat
     2221 gcgggtcttt ggcattgagc gtcctgataa tgtgactgca aatgaccgtc gcaatgccaa
     2281 ggcagttaac tttggagtgg tttatgggat ttcagacttt ggcttgtcta ataatttggg
     2341 aattagtcgt aaggaagcca aagcctacat tgatacctac tttgaacgtt ttccaggtat
     2401 taaaaactac atggatgaag tggtgcggga ggcgcgtgat aagagctatg tagagaccct
     2461 ctttaagcgt cgccgtgagt tgccagatat caattcgcgc aacttcaata ttcgtggttt
     2521 tgcggagcga actgctatca actcacctat ccagggttcg gcagcagata ttctcaagat
     2581 tgccatgatt cagctggata aagccttggt tgcaggtggt tatcagacca agatgctgtt
     2641 acaagtgcac gatgaaatcg tccttgaagt gcctaaatct gaattggtag agatgaaaaa
     2701 attggtgaaa caaaccatgg aagaagccat tcaactcagt gttcctctta tcgcagatga
     2761 gaatgaaggg gcaacctggt acgaggctaa ataaaaaggg ggctagtcct ccttttttgt
     2821 agtagaattc tgcaaacctt ttcaaaatgt gctatactga tgaaaaagga ggatttctat
     2881 gagtcaagaa tttatcaatc caagtgatgg cgtgattcgt cagtatctcg caacgagtaa
     2941 aacccttgct gtggtgggtt tgtctgaccg tgaagaaaca accagtaatc gagtaacaaa
     3001 ggaaatgcag gctcggggct ataaaatcat cccagtcaat cccaagacgg caggtggcga
     3061 aatcttgggt gaaaaggctt atgctagcct cgctgaaatt ccttttcctg tagatattgt
     3121 caatgtttat cgtcgcagtg aatttctgcc cgatgtggcg cgtgattttc tcaaagctga
     3181 tgccaagatt ttttgggcac agctaggact tgaaagttta gaagcgaaag agattttgcg
     3241 tgatggtgga tgtgatgata tcgtgatgaa tcgctgtatc aagagagaac atactcgctt
     3301 gattgaggaa gcataagaaa aaggtagctg atgggctacc ttttgtgtta tactcaatga
     3361 aaatcaaaga gcaaactagg aaactagctg cgggttgctc aaaacactgt tttgaggttg
     3421 cagatagaac tgacgaagtc agctcaaaac accgttttga ggttgtagat agaactgacg
     3481 aagtcagctc aaaacaccgt tttgaggttg tagatagaac tgacgaagtc agtaacatat
     3541 atacggcaag gcgacgttga cgtggtttga agagattttc gaagagtatt agaaaatgcc
     3601 gataagggtc tgcataccaa ggctggtgag gatgatggca atccagcaga cggctccgag
     3661 aacaatggat tttccactag atttgaccat agcgaccaga ttagttttga gaccgatggc
     3721 actcatggcc atgataatga ggaatttaga gagttgtttg agaggggtaa agaaactact
     3781 agacacaccg agagaggtca gaagggtggt taggagcgat gcaaggatga agtaaaggat
     3841 aaaaagtggg aagacttttt tcagttgtaa gccttgctta tttttttgct cgcgactttg
     3901 ccagtaggag agaaagagag tgatggggat gatagctagg gtgcgcgtga gtttgacaat
     3961 ggttgcagat tcgagggtat tggtctggta gagactgtcc caagcgctag ctgtggcggt
     4021 tacagaggaa gtatcattga ccgcagttcc tgcaaagagg gcgaagccgt cattggatag
     4081 atgaagccag gtaccgaggg ttggaaagat gagcgcagcc aagacattga agaaaaagat
     4141 aacggagatg gcttgggcta cttccttttc cttagcatgg ataacaggcg ctgtcgctgc
     4201 aatggcagaa cccccacaga tagaagaacc tactccaatc aaggtagcca gttttgtatc
     4261 cagggcaaag aagcgctgga agaggtaggc aacaatcaag gctattgaaa tggtggaaag
     4321 gatgacaggg agtgaagatt gcccaactgc gaagacttga gagatattga gaccaaaacc
     4381 aagtaagata acggcatact ggagcaattt cttggaacta aaggtcaatc cagcatccag
     4441 ttgtttatga gacgagagaa agggatgtag gagcatgccc ataaaaatcg caaaaacggg
     4501 tgcgccaatc acagggaaga atcctcctaa gtaccaagat aggatggaaa tgagaaggca
     4561 gaccaagatg cctgctccat tttttgatag aaatgacata aaaacctcca aatagaatct
     4621 gttaccatta tagacctgta aacaggaaaa gtaaaataga aagtggaaag ctattctcta
     4681 atgtattttt gcggtcgggg ggcttttgta gtataataga gatacgtttt gaaagtagga
     4741 ggtatctatg gacttaacta agcgctttaa taaacagtta gataaaattc aagtttcgtt
     4801 gattcgtcag tttgaccagg ctatttcgga gattcctggg gtcttgcgtt tgaccttggg
     4861 ggaacctgat tttacaacgc cagaccatgt caaggaggcg gccaagcgag cgattgatca
     4921 gaaccaatcc tactatacag ggatgagtgg tctgctgact ctacgtcagg cagccagtga
     4981 ctttgttaag gaaaagtacc aactggacta tgctcctgaa aatgaaatct tggttacaat
     5041 tggggcgaca gaggctttat ctgcgacttt gacggctatt ttggaagagg gcgacaaggt
     5101 acttttgcca gctcctgctt atccaggcta tgaaccgatt gttaacttag ttggggcaga
     5161 aattgttgag attgatacga ctgaaaatgg ttttgtcttg actcctgaga tgttggagaa
     5221 ggccattttg gagcagggtg ataagctcaa ggcggttatt ctcaactatc cagccaatcc
     5281 gacaggaatt acctacagtc gagagcagtt agaggccttg gcagctgttt tacgcaagta
     5341 cgaaattttt gttgtctgtg atgaggttta ctcagaattg acctacacag gcgaagccca
     5401 tgtgtctcta ggaacgatgt tgagagacca ggctattatt atcaatggtt tgtctaaatc
     5461 gcatgccatg acaggttggc gtttggggct gattttcgct cctgcggcct tcacagccca
     5521 gttaatcaag agtcaccaat acttggtcac tgccgcaaat accatggcgc aacatgctgc
     5581 ggtagaagcc ttgacggctg gtaaaaatga tgcggagccc atgaagaagg aatatatcca
     5641 gcgtcgggac tatatcatcg aaaaaatgac tgctcttggt tttgagatta tcaaaccaga
     5701 cggtgccttc tatatttttg ctaaaattcc agcgggctac aatcaagact cctttgcttt
     5761 tctgaaggat tttgctcaga agaaggccgt tgcctttatc cctggtgcag cctttggacg
     5821 ttacggggaa ggctacgtcc gcctatctta tgcagccagc atggagacta tcaaagaagc
     5881 catgaaacga cttgaggagt acatgagaga agcatgattc agtctatcac gagtcaaggc
     5941 ttggtgcttt acaatcgcaa ttttcgtgag gatgacaagc tcgtcaaaat ttttacagag
     6001 caggttggca aacgcatgtt ttttgtcaaa cacgctggtc agtctaagct ggcgcctgtt
     6061 attcagccct tggtgctggc acgatttcta ttgcgaatca atgatgacgg actcagttac
     6121 atcgaagact atcatgaggt catgactttt cccaagatta atagtgacct ctttgtcatg
     6181 gcctatgcga cctatgtggc agctcttgca gatgctagtt tgcaggacaa tcagcaggat
     6241 gctcccttgt ttgctttttt gcaaaagact ttggagttga tggaagcagg cttggattat
     6301 caggttttga ccaatatttt tgaaattcaa attttgactc gatttggaat cagcctcaat
     6361 tttaatgagt gtgtcttctg ccatcgggtt ggtcaggctt ttgacttttc tttcaaatat
     6421 ggagcctgcc tctgtccaga gcattatcat gaggataaga gacgttgtca tctcaatccc
     6481 aatatcccct atctgctcaa tcaatttcaa gctattgatt ttgagacttt ggagaccatt
     6541 tcgctcaagc ctggaatcaa gcaagagcta cgccaattta tggatcaact atatgaagag
     6601 tacgttggga ttcacctaaa atcaaagaaa tttattgatt ccctagcaga ctggggacaa
     6661 ttactaaaag aggaaaagaa atgaaaaaaa tcgcagtaga tgccatgggg ggcgattacg
     6721 cacctcaggc cattgttgag ggtgtcaatc aagccctatc tgacttttca gatatcgagg
     6781 ttcaacttta cggagatgaa gctaaaatca agcaatatct gacagcgaca gagcgcgtca
     6841 gcattatcca tacggatgag aagattgatt cggatgatga acctacgaga gctattagga
     6901 ataagaaaaa tgccagtatg gtattggcag ccaaggctgt caaagatggt gaagcagacg
     6961 ctgtcctttc ggctgggaat acaggtgcct tgttggctgc tggattcttc atcgtgggtc
     7021 gtatcaagaa tatcgaccgt cctgggctta tgtcgacttt gccgactgta gatgggaagg
     7081 gatttgacat gctagacctc ggtgccaatg cggaaaatac agcccagcac ctccatcaat
     7141 acgcggttct aggatccttc tatgctaaaa atgttcgtgg cattgcgcaa ccacgtgttg
     7201 gcttgctcaa taacggaaca gagagtagca agggcgatcc gcttcgtaag gaaacttatg
     7261 aattactagt ggctgatgaa agtttgaact ttatcggaaa tgtggaagcg cgtgatttga
     7321 tgaatggtgt tgcagatgtt gttgtggcag atggtttcac gggaaacgct gtgctcaaat
     7381 ccatcgaagg gacagctatg ggaatcatgg gcttgctcaa gacagctatt acaggtggtg
     7441 gtcttcgagc gaaactaggt gccctccttc tcaaggacag cctcagaggt ttgaaaaaac
     7501 agctcaatta ttcagatgtt ggtggagcgg tcttgtttgg tgttaaggca cctgttgtca
     7561 agactcatgg ctcaagcgat gccaaggctg tttatagtac gattcgccag attcgtacca
     7621 tgctagaaac agacgtagtt gcccagactg cgcgtgaatt ttcaggagaa taaaagagat
     7681 gacagaaaaa gaaatttttg accgtattgt gaccattatc caagagcgac agggagagga
     7741 ctttgtcgtg acagaatcct tgagtctgaa agacgatttg gatgcggatt ctgttgactt
     7801 gatggagttt atcttgactc tggaagatga atttagtatc gaaatcagcg atgaagaaat
     7861 tgaccaactc caaaacgtag gagatgtggt taaaatcatt caaggaaaat agcaatcgga
     7921 gttccaagtc aacggaagta gatggttttt agaaatgaga aatatcggac aagctggtaa
     7981 aatcttggct gacagtggtt atcaagggct catgaagata tatcctcaag cacaaactcc
     8041 gaggaaatca agtaaactta agccattaac tcttgaagat aaagcctgta atcatgcgct
     8101 atctaaggag agaagcaagg ttgagaatat ctttgccaaa gtaaaaacgt ttaaaatgtt
     8161 ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg
     8221 tattatcaat catgaactag gattctagtt ttgcaggaag tctaatagta aaaaagtgat
     8281 tagaaaacat cttttttaaa aatagagatg attttgaaac aaaaaagcta attcaagacg
     8341 tttcgatgcc aattcaagat ttggatgaaa aaaattaata gatactgtta tactaaactt
     8401 gtcaagtttg taacaagaca aatattaaaa ataaaaaaga ggtattcgtt atgaatacaa
     8461 aaaagatgtc acaatttgaa attatggata ctgagatgct tgcttgcgtt gaaggtggcg
     8521 gatgcaattg gggagatttt gccaaagcag gtgttggagg aggagtagca cgaggtcttc
     8581 agctaggaat taaaacaaga acatggcaag gtgcagcaac tggtgctgcg ggaggagcta
     8641 tacttggagg tgtggcctat gcagcgacat gttggtggta attatggatt ttaaaagttt
     8701 tattattggt ttagtagttg gtatatttgg tccttatatg gatgatttaa ttagaaaaaa
     8761 atttttaaag tcttcggaga agaaaacaga aaaatctgtt aaaaaataat caaaactata
     8821 aatgatgaat ctgaatcaaa attattttgc gcatgtaaag aggagtctta tagtaacgag
     8881 tcaaaaaagg agtaactatg aatcgtgatt tagaacggtg ttatctattc tgactaggaa
     8941 tagatcatac cagaggtagc ttagaaatag cagggacatt agaaattgaa gtaataaata
     9001 ggatgtcgta agtgttacta tcaatgattt atttgtttca agcttgccta gggtgacagt
     9061 aaaaaatcaa tttcctttca atagcatatt tttagtgggc aggactcttg ttctgcctat
     9121 ttttttatcc aaaaagtgca gttgggaggg agataggctc atttgggaag gaagtccagt
     9181 ttttgtttag tgattgaggt aagatagttg ttatcagatg agtttatact cttcgaaaat
     9241 caaattcaaa ccacgtcaac gtcgccttga cgtatatatg tgactgactt cgtcagtcct
     9301 atctacaacc tcaaaacagt gttttgagca gcctgcggct agtttcctag tttgctcttt
     9361 gattttcatt gagtattagg gaaaaggaga tgaatatgaa atttgggaaa cgtcactatc
     9421 gtccgcaagt ggatcagatg gactgcggtg tagcttcatt agccatggtt tttggctact
     9481 atggtagtta ttattttttg gctcacttgc gagaattggc taagatgacc atggatggga
     9541 cgacggcttt gggcttggtc aaggtggcag aggagattgg ttttgagacg cgagccatta
     9601 aggcggatat gacgcttttt gacttgccgg atttgacttt tccttttgtt gcccatgtgc
     9661 ttaaggaagg gaaattgctc cactactatg tggtgactgg gcaggataag gatagcattc
     9721 atattgccga tccagatccc ggggtgaagt tgactaaact gccacgtgag cgttttgagg
     9781 aagaatggac aggagtgact ctttttatgg cgcctagtcc agactataag cctcataagg
     9841 aacaaaaaaa tggtctgctc tcttttatcc ctatattagt gaagcagcgt ggcttgattg
     9901 ccaatatcgt tttggcaaca ctcttggtaa ccgtgattaa cattgtgggt tcttattatc
     9961 tgcagtctat cattgatacc tatgtgccag atcagatgcg ttcgacacta gggattattt
    10021 ctattgggct agtcatcgtc tacatcctcc agcaaatctt gtcttacgct caggagtatc
    10081 tcttgcttgt tttagggcaa cgcttgtcga ttgacgtgat tttgtcctat atcaagcatg
    10141 tttttcacct ccctatgtcc ttctttgcga cacgcaggac aggggaaatt gtgtctcgtt
    10201 tcacggatgc taacagtatc atcgatgcgc tggcttcgac catcctttcg attttcctag
    10261 atgtgtcaac ggttgtcatt atttcccttg ttctattttc acaaaatacc aatctctttt
    10321 tcatgacttt attggcgctt cctatctaca cagtgattat ctttgccttt atgaagccgt
    10381 ttgaaaagat gaatcgggat accatggaag ccaatgcggt tctgtcttct tctatcattg
    10441 aggacatcaa cggtattgag actatcaagt ccttgaccag tgaaagtcag cgttaccaaa
    10501 aaattgacaa ggaatttgtg gattatctga agaaatcctt tacctatagt cgagcagaga
    10561 gtcagcaaaa ggctctgaaa aaggttgccc atctcttgct taatgtcggc attctctgga
    10621 tgggggctgt tctggtcatg gatggcaaga tgagtttggg gcagttgatt acctataata
    10681 ccttgctggt ttactttacc aatcctttgg aaaatatcat caatctgcaa accaagcttc
    10741 agacagcgca ggttgccaat aaccgtctaa atgaagtgta tctagtagct tctgagtttg
    10801 aggagaagaa aacagttgag gatttgagct tgatgaaggg agatatgacc ttcaagcagg
    10861 ttcattacaa gtatggctat ggtcgagacg tcttgtcgga tatcaattta accgttcccc
    10921 aagggtctaa ggtggctttt gtggggattt cagggtcagg taagacgact ttggccaaga
    10981 tgatggttaa tttttatgac ccaagtcaag gggagattag tctgggtggt gtcaatctca
    11041 atcagattga taaaaaagcc ctgcgccagt acatcaacta tctgcctcaa cagccctatg
    11101 tctttaacgg aacgattttg gagaatcttc ttttgggagc caaggagggg acgacacagg
    11161 aagatatctt acgggcggtc gaattggcag agattcgaga ggatatcgag cgcatgccac
    11221 tgaattacca gacagaattg acttcggatg gggcagggat ttcaggtggt caacgtcaga
    11281 gaatcgcttt ggcgcgtgct ctcttgacag atgcgccggt cttgattttg gatgaggcga
    11341 ctagcagttt ggatattttg acagagaagc ggattgtcga taatctcata gctttggaca
    11401 agaccttgat tttcattgct caccgcttga ctattgctga gcggacagag aaggtagttg
    11461 tcttggatca gggcaagatt gtcgaagaag gaaagcatgc tgatttgctt gcacagggtg
    11521 gcttttacgc ccatttggtc aatagctaga aagaggagag gatgaaacca gaatttttag
    11581 aaagtgcgga gttttataat cgtcgttacc ataatttttc cagtagtgtg attgtaccca
    11641 tggcccttct gctcgtgttt ttacttggct ttgcaactgt tgcagaaaag gagatgagtt
    11701 tgtccactag agctactgtc gaacctagtc gtatccttgc aaatatccag tcaactagca
    11761 acaatcgtat tcttgtcaat catttggaag aaaataagct ggttaagaag ggggatcttt
    11821 tggttcaata ccaagaaggg gcagagggtg tccaagcgga gtcctatgcc agtcagttgg
    11881 acatgctaaa ggatcaaaaa aagcaattgg agtatctgca aaagagcctg caagaagggg
    11941 agaaccactt tccagaggag gataagtttg gctaccaagc cacctttcgc gactacatca
    12001 gtcaagcagg cagtcttagg gctagtacat cgcaacaaaa tgagaccatc gcgtcccaga
    12061 atgcagcagc tagccaaacc caagccgaaa tcggcaacct catcagtcaa acagaggcta
    12121 aaattcgcga ttaccagaca gttaagtcag ctattgaaac aggtgcttcc ttggccggtc
    12181 agaatctagc ctactctctt taccagtcct acaagtctca gggcgaggaa aatccccaaa
    12241 ctaaggttca ggcagttgca caggttgaag cacagatttc tcagttagaa tctagtcttg
    12301 ctacttaccg tgtccagtat gcaggttcag gtacccagca agcctatgcg tcagggttaa
    12361 gcagtcaatt ggaatccctt aaatcccaac acttggcaaa ggttggtcag gaattgaccc
    12421 ttctagccca gaaaatcttg gaggcagagt caggtaagaa ggtacaggga aatcttttag
    12481 acaaggggaa aattacggca agtgaggatg gggtgcttca tcttaatcct gagaccagtg
    12541 attctagcat ggttgcagaa ggtgccctac tagcccaact ttatccatct ttggaaagag
    12601 aagggaaagc caaactcaca gcctatctaa gttcaaaaga tgtagcaaga atcaaggtcg
    12661 gtgattctgt tcgctatact acgactcatg atgccgggaa tcaacttttt ctagattcta
    12721 ctattacaag tattgatgcg acagctacta agactgagaa agggaatttc tttaaaatcg
    12781 aggcggagat taatctaact tcggagcagg ctgaaaaact taggtacggg gtggaaggcc
    12841 gtctacagat gattacgggc aagaaaagtt atctacgtta ttatttggat caatttttga
    12901 acaaagagta atgttcgtgt ttttagagtt aaataatttt taaactgtga gaaagattct
    12961 tcttgcagtt ttttctttac aatttttgaa aaacatctgc tatttattcg gttaaattct
    13021 tgtgtttttt ggttttttgt ggtaaaatgt gctcaagtaa tacgaaaggc gaactttaaa
    13081 atgtcaaaac aattgatcta ttcgggaaaa gctaaagata tctatacaac tgaggatgaa
    13141 aatcttatta tttcaactta caaggaccag gcgactgctt tcaacggtgt caagaaggag
    13201 cagattgcag gtaagggagt cttgaataat cagatctcat cttttatttt tgagaaatta
    13261 aatgcggctg gtgtggcgac tcactttgtg gagaaacttt cagacacgga acaactcaat
    13321 aaaaaggtta agattattcc tttggaagtc gtgctccgca actatactgc tggttccttt
    13381 tcaaaacgtt ttggtgtgga tgagggaatc gccttggaga ctccgattgt cgaattttac
    13441 tacaaaaatg atgatttgga tgatccattt atcaatgatg agcatgtgaa attcctacag
    13501 attgcgggtg accagcagat tgcctacttg aaggaagaaa cgcgtcgtat caatgaacta
    13561 ttgaaagtct ggtttactga gattgggctt aaattgattg actttaagct agagttcggt
    13621 tttgacaagg atggcaagat tatcttggca gacgaatttt caccagataa ctgccgcttg
    13681 tgggacgctg atggcaacca catggataag gatgttttcc gtagaggatt gggagaacta
    13741 accgacgttt atgagattgt ttgggaaaag ttgcaggaat tgaaataatc tgtttgcaac
    13801 ggaaaacctt cgtctctcaa ctaaaaggac tcaggctgaa aaggtccccc agaccttttc
    13861 actctgtaga gaactaggtg aactaacaga tgtttacgaa attgtctggg aaaagttgca
    13921 gggtttaaaa taacaacctc aaggctgttt gggaatattg caagagctga aataaaggaa
    13981 taagaattga tggataaacg tatttttgtt gaaaaaaagg ctgattttca ggtcaagtca
    14041 gagagtttgg ttagagagct ccagcacaac ttgggactgt caagcttgaa aagtattcgt
    14101 attgtgcaag tatatgatgt atttgacttg gctgaggact tgtttgcacc tgcagagaag
    14161 cacattttct ctgagcaggg aaccgaccat gttttagatg aagtatctgt gcaggcggat
    14221 cttgctaact atgctttctt tgccattgaa agtctgccag ggcagtttga ccagcgtgca
    14281 gcttcgtcac aggaagcctt gcttttgttg ggaagttcga gtgacgtgac agtcaacaca
    14341 gcccaacttt acttggtgaa taaagatatt gatgcgactg agttggaagc tgtcaaaaac
    14401 tacctgctca atccagttga ttctcgtttc aaggatatca cgacagggat tgccaagcag
    14461 gagttttcag agtcagacaa gaccattcca aaattgactt tctttgaaag ctatacagca
    14521 gaagactttg ctcgctacaa ggccgagcaa gggatggcca tggaagtgga tgatttgctc
    14581 tttatccaag actactttaa gtcaatcggg cgcgtgccaa ctgagactga actcaaggtt
    14641 ttggacactt actggtctga ccactgccgt catacgactt ttgagacaga gttgaaacac
    14701 atcgactttt cagcttctaa atttcaaaag caattgcagt caacctatga caagtatatt
    14761 gccatgcgcg aggagttagg tcggtctgaa aaaccacaaa ccttgatgga tatggcgact
    14821 attttcggtc gttatgagcg tgctaacgga cgattggatg atatggaagt ctctgacgaa
    14881 atcaatgcct gctcagttga aattgaagtg gatgttgatg gtgtcaagga accttggctc
    14941 ctcatgttta aaaatgaaac ccacaaccat ccaacagaaa ttgagccatt tggtggagcg
    15001 gctacctgta tcggtggagc tattcgtgat ccgttgtcag gccgttccta tgtttaccaa
    15061 gccatgcgta tttcaggtgc tggtgatatt acagcaccga tttcggaaac tcgtgctggg
    15121 aaattgccac aacaagtcat ttctaaaaca gcagctcatg gttattcttc atatggtaac
    15181 cagattgggc ttgccacaac ctacgttcgt gaatacttcc acccaggctt tgtagctaaa
    15241 cgtatggaac ttggtgccgt tgttggtgcg gctcccaagg gcaatgttgt ccgtgaaaaa
    15301 cctgaagcag gtgatgtgat catccttctc ggaggcaaaa caggtcgtga tggtgtcggt
    15361 ggtgcgacgg gctcttctaa ggttcaaaca gttgagtctg tagagactgc tggtgctgag
    15421 gttcaaaaag gaaatgccat cgaagaacgc aagattcagc gcctcttccg taatggcaat
    15481 gtcactcgtc tgatcaagaa gtccaatgac tttggggcag gcggcgtctg tgtggctatc
    15541 ggtgaattgg cagacggtct tgaaatcgac ctcaacaagg tgcctcttaa ataccagggc
    15601 ttgaatggta cagaaattgc catctctgaa tcacaagaac ggatggcggt cgtggttcgt
    15661 cctgaagatg tggatgcctt cgttgccgaa tgtaacaaag aaaatattga tgctgttgtg
    15721 gtggcgacag taactgaaaa accaaatctt gtcatgcact ggaatggtga gacaatcgtt
    15781 gacttggagc gtcgtttcct tgacaccaat ggtgtgcgcg tggttgtcga tgccaaagtt
    15841 gtggacaagg atgtcaaact cccagaagag cgtcaaacat ctgctgaaac actggaatca
    15901 gataccctta cggttctatc tgacctcaac catgcaagtc aaaaaggatt acagactgtc
    15961 tttgactgct ctgttggacg ctcaacggtt aatcacccac ttggtggtcg ttaccaactc
    16021 acaccaactg aggcatctgt gcagaaattg ccagttcaac acggtgtgac tcatactgcg
    16081 tcggtcattg ctcaaggttt caacccatat gtagctgaat ggtctccata ccacggtgct
    16141 gcttacgcgg ttatcgaagc aactgctcgt ttggtggctg ctggtgccaa ctggtctaag
    16201 gctcgtttct cttaccaaga atatttcgag cggatggaca agcaagcaga gcgttttggt
    16261 cagccagtag ccgcccttct aggctctatt gaagctcaga ttcaacttgg cttgccatct
    16321 atcggtggta aggactccat gtctggtacc tttgaagaat tgaccgttcc gccaaccttg
    16381 gttgcctttg gggtgacgac ggcagatagc cgtaaggtgc tctctccaga atttaaagct
    16441 gttggggaaa atatctacta catcccaggt caagccctct ctgcagagat tgattttgac
    16501 ttgattaaga aaaattttgc tcagtttgaa gcaagccagg ctgaccataa agtgacatct
    16561 gcatcagctg tcaaatacgg tggtgtagtt gaaagtttgg ctcttgctac ctttggaaac
    16621 tatattggtg cagaggtgac cttgcctgaa cttaaaacag ctttgacagc tcaattaggc
    16681 ggctttgtct tcacatctcc tgaagaaatt gctggagtag agaaggttgg acaaacgaaa
    16741 gcagacttta cactgactgt caacggtgtg aagctagatg gacacaagct tgacagtgca
    16801 tttcaaggga cattggaaga agtttaccca acagaattta cccaagcgaa agaactagaa
    16861 gaagtaccag ctgtggcatc agatgttgtg attaaagcca aagaaaaggt tgaaaaacct
    16921 gtggtttaca tcccagtctt tccaggaacc aactcagaat atgattcagc taaggcattt
    16981 gaaaaagaag gcgcagaggt caacttggtg ccatttgtga ccttgaatga agaggctatt
    17041 gtcaagtcag ttgaaaccat ggttgacaac atcagtgaag ctaacattct cttctttgca
    17101 ggtggcttct cagctgcgga cgaaccagat ggttcagcta agtttattgt caatatcctg
    17161 ctcaatgaaa aagtgcgtgc agctattgat agctttatcg ctcgtggtgg cttgattatc
    17221 ggtatttgta atggattcca agccttagtc aaatcgggtc tcctaccata cggaaacttt
    17281 gaagatgcta acagtactag cccaaccctc ttctacaatg atgccaacca acacgtggcc
    17341 aagatggtgg aaactcgcat tgccaatacc aactcaccat ggttggctgg tgtgcaagtg
    17401 ggcgatatcc acgctattcc tgtttcgcac ggtgaaggga agtttgtcgt gacggttgag
    17461 gaatttgcag agctccgtga caatggacaa attttcagcc aatacgttga ctttaacggt
    17521 aaaccaagta tggattctaa gtacaatccg aatggttctg tccatgccat cgaaggaatt
    17581 accagcaaga atggtcaaat catcggtaag atgggccact cagaacgtta tgaggacggt
    17641 cttttccaaa atatcccagg caataaagac cagcacctgt tcgcatcagc ggttaaacat
    17701 ttcactggaa aataagactt acagattttc taatagatag tatcagtaat gtaaaagtca
    17761 tgtaaatcta gctcttgatg attacaaatg aaaattaggt ataaaaaatg acatacgaag
    17821 taaaatctct taatgaagaa tgtggtgttt tcggtatttg gggacatcca gatgctgcta
    17881 agttgaccta ttttggactc cacagtcttc aacaccgtgg tcaggagggg gcaggaatcc
    17941 tctccaatga tcaaggacag ctgaagcgcc atcgtgacat ggggctttta tcagaagttt
    18001 tcagaaatcc agccaatttg gataaattga caggagctgg tgcgattggg catgtgcgtt
    18061 atgcgactgc tggcgaagct tctgttgata acatccaacc cttcctcttc cgttttcacg
    18121 atatgcagtt tggtttggct cataatggaa atctgaccaa tgcagcctct ctcaagaaag
    18181 aactggaaca aagaggagca attttcagcg cgacttcgga ctctgaaatc ttggctcacc
    18241 tcattcgtcg cagtcataat cctagcctga tgggcaaaat caaggaagcg ctcagccttg
    18301 tcaaaggtgg ttttgcctat atcttgctgt ttgaggacaa gttgattgcg gctcttgacc
    18361 ctaatggctt tcgtccgctt tctatcggga aaatggccaa cggagcggtg gttgtttcct
    18421 ctgaaacctg tgcttttgag gtcattggtg ccgagtggat ttgtgatttg aagccaggtg
    18481 agattgtgat cattgatgac gagggcattc agtatgacag ctatacagat gatacccagt
    18541 tggcgatttg ttctatggag tatatctact ttgcccgccc tgattctaat atccacggtg
    18601 tcaatgtcca tacggcacgt aagagaatgg gagcgcaatt ggcgcgagaa tttaagcatg
    18661 aggcagatat tgtagttggt gtgcccaatt cttccctaag cgcggctatg ggatttgcgg
    18721 aagaatcagg cttaccaaat gaaatgggtc tgatcaaaaa ccaatacacc cagcgaactt
    18781 ttatccaacc gactcaagaa ttgcgggagc aaggagtgcg gatgaaactg tctgctgttt
    18841 cgggtgttgt caaaggcaaa cgtgtggtca tggtggatga ttccattgta cgtggaacaa
    18901 cctctcgtcg tatcgttcag ctcttgaaag aagcgggtgc gactgaggtt cacgttgcca
    18961 ttggaagtcc tgcactagcg tatccatgtt tctacgggat tgatatccag acccgtcagg
    19021 agctgattgc agccaatcat acggtcgaag aaactcgcca aatcattggt gcggacagtc
    19081 tgacttatct ttcaattgat agcttgattg agtcgattgg tatcgaaaca gatgcgccga
    19141 acggtggtct ctgtgtcgct tactttgacg gtgactaccc aacgcctctc tatgactacg
    19201 aagaagacta tcgtagaagt ttggaagaaa agaccagttt ttacaagtag gcgacagatt
    19261 ctccattaaa gaaaaggaaa aaacaaatga caaataaaaa tgcatatgcc cagtcgggtg
    19321 tggatgttga agcgggttat gaagttgttg aacggattaa aaagcacgtg gcccgtacgg
    19381 agcgtgcagg tgtcatggga gctcttggtg gctttggtgg tatgtttgac ctttccaaga
    19441 ctggggttaa agaacccgtc ttgatttcag ggactgacgg tgtcggaacc aagctcatgt
    19501 tggctatcaa gtacgacaag cacgatacca tcgggcagga ctgtgtggcc atgtgtgtca
    19561 acgacatcat tgctgcaggt gcggaacccc tctattttct cgactacgta gcgacaggga
    19621 agaatgaacc agctaagcta gaacaagtgg ttgctggtgt ggcagaaggt tgtgtgcagg
    19681 ctggtgctgc cctcatcggt ggggaaacgg ctgaaatgcc gggcatgtac ggcgaagacg
    19741 actatgactt ggctggtttt gcggtcggtg tggctgaaaa atctcaaatc attgacggtt
    19801 caaaggtggt agagggagat gttcttctcg gacttgcttc aagtgggatt cactcaaatg
    19861 gttactcttt ggttcgtcgt gtctttgcgg attacacagg tgaggaagtc ctaccagaat
    19921 tggaaggcaa gaaacttaag gaagttctac ttgagccgac tcgtatctat gtcaaggctg
    19981 tcttgccgct catcaaagaa gagttggtca acggcattgc ccacatcaca ggtggtggct
    20041 ttatcgaaaa tgtccctcgt atgtttgcag atgacctagc tgctgaaatt gatgaaagca
    20101 aagttccagt gcttccaatt ttcaaagccc ttgaaaaata tggtcagatt aaacacgaag
    20161 aaatgtttga aatcttcaat atgggtgtgg gacttatgtt ggcggtcagc cctgaaaatg
    20221 tagagcgtgt aaaagaattg ttggatgaag cagtctatga aattggtcgc atcgtcaaga
    20281 aagaaaacga aagtgtcatt atcaaatgaa aaaaatagcg gtttttgcct ctggtaatgg
    20341 ctcaaatttt caggtgattg ccgaagaatt tccagtggag tttgtctttt cagaccatcg
    20401 tgatgcctat gtgcttgagc gtgcaaagca gctcggcgtt ctgtcctatg cttttgaact
    20461 caaggagttt gagagcaaga cagactacga agcagccctt gtcgaactct tggaagaaca
    20521 ccagattgac ttggtttgcc tagcaggcta cataaaaatc gttggaccaa ccttattgtc
    20581 ggcttatgaa ggtcggattg tcaacattca tccagcctac ttgccagaat ttccaggagc
    20641 tcatgggatt gaggatgctt ggaatgctgg cgtgggtcag tctggtgtga ccattcactg
    20701 ggtggattcg ggtgtggata caggccaggt catcaaacag gttcgtgtgc cacgactagc
    20761 tgatgatacc attgacagat ttgaagctcg catccatgaa gcagagtaca ggttgtatcc
    20821 ggaagtagtg aaggctctat ttacagattg actttttgat gattcatatg atatctttga
    20881 ttttaaattg gagtcagtgt ttgttgaaga cggcttcaaa cggaggtatt tgtaatgtta
    20941 gaatctaaaa aaacaactcg atatgtattt tatgtctatc tgatgttatt aacttgggga
    21001 atcttattta agtttgaaac aaatcctgaa tttatagcat ttttcttagc tccaaggtat
    21061 atcaattgga ttccattttc agaaccacta atagtcgatg gaaaaattgt ttttgctgaa
    21121 atgttattta atctgatttt ctttattcca ttaggtgttt gtttcccttt gataaaaact
    21181 aatttatcta gtttaagaat agtcgggaca ggtttcttga ttagtttatt gtttgagtgc
    21241 ttacagtata ttttagcaat aggtataaca gatataacgg atttgacttt aaatacgcta
    21301 ggtgtctgtg taggcttact gatttatcaa atttttataa gagtgttcaa atcacagact
    21361 agaaaatgga tcaatatctt aggtatgctt agccttggtt ttgcttatct tgttttactg
    21421 ttactgcatt taattggtgt ttaactaatg attaaaaagg agaatataat gactaaacgc
    21481 gtcttaatca gcgtctcaga caaagcgggc attgttgaat ttgcccaaga actcaaaaaa
    21541 cttggttggg agattatctc aacaggtgga actaaggttg cccttgataa tgctggggtg
    21601 gataccattg ctatcgatga tgtgactggt ttcccagaaa tgatggacgg tcgtgtgaag
    21661 accctccacc caaatatcca cggagggctt ctcgctcgtc gtgacttgga tagccacttg
    21721 gaagcggcta aggacaacaa gattgagctc attgaccttg tggtggtcaa cctttaccca
    21781 tttaaggaaa ctatccttaa accagatgtg acttatgctg atgcagttga aaatatcgat
    21841 attggtgggc cgtctatgct tcgttcagca gcgaaaaatc atgccagtgt tacagttgtg
    21901 gtagatcctg ctgactacgc tgtggttttg gacgaattgg cagcaaacgg cgaaacctct
    21961 tatgaaactc gccaacgttt agcagccaaa gtatttcgtc acacagcggc ttatgacgcc
    22021 ttgattgcag aatacttcac agctcaagtg ggtgaaagca agcctgaaaa actcactttg
    22081 acttatgacc tcaagcaacc aatgcgttac ggtgagaatc ctcaacaaga cgcggacttt
    22141 taccagaaag ctttgcctac agattactct attgcttcag ccaaacagct caacgggaaa
    22201 gaattgtcat ttaataatat ccgtgatgca gatgctgcta tccgtatcat ccgtgacttc
    22261 aaagatagtc caaccgttgt ggctctcaaa cacatgaatc catgtggaat tggtcaagct
    22321 gatgacatcg agactgcttg ggactacgct tatgagtctg acccagtatc tatctttggt
    22381 gggattgtcg tcctcaaccg tgaggtggat gctgcgacag ctgagaagat gcacggcgtt
    22441 ttcctcgaaa tcatcattgc accaagctat acggatgaag cgctagccat tttgatcaat
    22501 aaaaagaaaa acttgcgtat ccttgccttg ccatttaatg ctcaagaggc tagcgaagtg
    22561 gaagcagaat acacaggtgt agtcggtgga cttctcgtgc aaaatcaaga cgtggtcaag
    22621 gaaagcccag ctgactggca agtggtgacc aaacgtcagc caaccgagac agaagcgact
    22681 gctcttgagt tcgcttggaa ggctatcaag tacgtcaaat caaatggtat tatcgtgacc
    22741 aacgaccaca tgacacttgg tgttggtcca ggtcaaacca accgtgtggc ttctgttcgc
    22801 cttgccattg accaagccaa agatcgtctg aacggggcgg tccttgcttc agatgccttc
    22861 ttcccatttg cggataacgt ggaagaaatc gccaaagcag gaattaaggc catcatccag
    22921 cccggtggct ctgtccgtga ccaagaatcc atcgaagcag cggataaata cggcttgact
    22981 atggtcttta caggtgtgag acattttaga cattaagaag ataaaaggga agaaaacagt
    23041 ttctttcctt ttttggctta aaatgctaac tgaaacaaga ttaaaacgaa cgtttatgtt
    23101 ataatgttag taaatgattc gtaaaagagg ttgagaaatg aaactgcttg ttgtcggttc
    23161 gggtggtcgt gagcatgcga ttgctaaaaa gttacttgaa tcaaaagacg tggaaaaagt
    23221 ctttgtagct cctgggaatg atgggatgac tctggatggt ttggaattgg taaatatctc
    23281 tatttccgaa cattctaaat tgattgactt cgcaaagacc aatgatgttg cttggacctt
    23341 tatcggtcca gatgatgccc ttgctgctgg tatcgtggat gattttaacc aagctgggct
    23401 taaggccttt ggtccgacta gggctgcagc ggagctggag tggtccaagg attttgccaa
    23461 ggaaatcatg gtcaaatatg gtgtttcgac agcagcctat ggcacatttt cagatttcga
    23521 ggaagcaaag gcctatatcg aaaagcatgg tgcgcctatc gtagtcaagg cggatggctt
    23581 ggcgcttggg aagggtgtcg tcgttgctga gacggttgag caagcggtcg aagccgctca
    23641 tgagatgctt ttggacaata aatttggtga ctcaggtgcg cgcgtggtta ttgaggaatt
    23701 ccttgaagga gaggaatttt cactctttgc ctttgtcaat ggtgataagt tctacatcat
    23761 gccaacggct caggaccaca aacgtgccta cgatggcgac aaagggccta acacgggtgg
    23821 tatgggtgcc tatgcgccag ttccacactt accacagagt gtagttgata cagcggttga
    23881 caccattgtc aagccagttc tagaagggat gattaaagaa ggtcgccctt atttgggagt
    23941 tctttacgca gggcttatcc tgacagctga tggaccgaaa gtcattgagt tcaacgctcg
    24001 gttcggagat ccagaaactc agattatctt gcctcgcttg acctctgact ttgctcaaaa
    24061 tatcacagat atcctggata gcaaggagcc aaatatcatg tggacggaca agggtgtgac
    24121 tctgggtgtg gttgtcgcat ccaagggcta cccgctagac tatgaaaggg gcgttgagtt
    24181 gccagccaag acagaaggcg atgtcatcac ctactatgca ggggctaagt ttgcggaaaa
    24241 tagcagagca ctgctctcaa acggcggacg agtttatatg ctcgttacca cagcagatac
    24301 cgtcaaagaa gcccaagcca gcatctacca agaactatac caacaaaaaa tagaaggact
    24361 cttctaccga acagatatcg gaagcaaggc aattaagtaa agatataaga ataacgcgcc
    24421 gtagtcgcca aacacgataa tggtcgtcgt ggtgaaaaga ccagaacagt gaatgttctg
    24481 gtcagggggg aacttggaga ccgtaggctc aaagtttagg aatgaaaccg aaggtttgct
    24541 tacgcctcca tcacctaaga ccattatcaa aaagaaaaat aaaaattcac aaaatacgtt
    24601 aatgatcgta tggtttgcga gcgttagcga gctaatatag aacaatcacc gccgttgtga
    24661 aagaacgatt ggatgataat ccaatcgttc agggaaattg gaagaccttg ggtttccaat
    24721 ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg tgattgttga
    24781 aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg gctcaaaatc
    24841 cgactgggca accatgcaaa aaacagcaga agtcctagac cgcttcggtg tagcctacga
    24901 aaagaaagtt gtttccgcac accgtacacc agacctcatg ttcaaacatg cagaagaagc
    24961 ccgtagtcgt ggcatcaaga tcatcatcgc aggtgctggt ggcgcagcgc atttgccagg
    25021 catggtagct gccaaaacaa cccttccagt cattggtgtg ccagtcaagt ctcgtgctct
    25081 tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc ctgttgcgac
    25141 catggctatc ggtgaagctg gagcgactaa cgcagctctc tttgccctcc gtctcctctc
    25201 tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac aaggaaaaat
    25261 cgcagaggag tcgtcaaatg agctcatcta aaacaatcgg aattatcggt ggcggtcaac
    25321 tgggtcagat gatggccatt tctgctatct acatgggcca caaggttatc gcgctggatc
    25381 ctgcggcgga ttgcccggcc tctcgcgtgg cggaaatcat tgtggcacct tataacgatg
    25441 tggacgccct ccgtcagttg gcagaccgtt gcgatgtcct cacttacgag tttgaaaatg
    25501 tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa ggaacagatc
    25561 tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac aaggctcaag
    25621 tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat atcgacttgt
    25681 cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga caaaaggtta
    25741 ttcgttcaga agtagacttg gaagcagcct atgcgctagc agactcagca gactgcgtct
    25801 tggaagaatt tgtcaacttt gaccttgaga tttctgtcat cgtgtcagga aatggcaagg
    25861 aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg tctaagacca
    25921 tcgtaccagc ccgcatttct gaaagtctag tagacaaggc taaagctatg gcagtgcgaa
    25981 tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg actgatgatg
    26041 acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat tctattgaag
    26101 cctgtgattt ctctcagttt gacacccata ttctcggtgt tctcggagca ccattaccag
    26161 tcatcaaact ccatgcgcca gccgttatgc ttaatgtcct cggtcagcat gtcgaggctg
    26221 ctgagcaata tgtgacagaa aattcaagcg cccacctcca catgtatggt aaaatagaag
    26281 cgaagcacaa ccgcaagatg ggacatgtga ccttgtttag tgatgtaccg gatagtgtgg
    26341 atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt atcgttaata
    26401 catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc agtgctgacc
    26461 aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa aattatttag
    26521 ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac ccgtctgtgt
    26581 ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct tattcccaac
    26641 agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc ctgagatggc
    26701 gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa tcctctctga
    26761 cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga ttcgcaagaa
    26821 ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc acgatgtggt
    26881 ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg ttcactatgg
    26941 gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc aggccaacga
    27001 catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg ccaaggagca
    27061 caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga caacctttgg
    27121 tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt tcgagcatgc
    27181 agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg ccaatatccc
    27241 accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag aaatctctac
    27301 acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca gcattgcgac
    27361 ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc aacgcgaagt
    27421 agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca aacgcaaccc
    27481 aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca tgattacggc
    27541 ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag ctgagcgtat
    27601 catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg gaaatatcgt
    27661 caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga cttttggtct
    27721 tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc gtgagcaagc
    27781 ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag actttaaacc
    27841 acttcttgag gcagattcag aagtaacatc acgtctcact caagaagaaa tcgatgaaat
    27901 cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc ttggactagg
    27961 tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt atcgaaaaga
    28021 cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggacatg agtcctgcga
    28081 ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct gttaccacag
    28141 gagctggatc ttgaggaaga gctttgcttt cctcagcagg agcagttgat ggagctggtt
    28201 ggcttgggat ttctagtttt ggtttttctt cagcaatagc ggcttgtccg ttttcatcgc
    28261 ctacatgtgt taccatagtt ccgacttcga ctatttgagt aacggcttcc tgtgctacga
    28321 cactatttac aagtgttttc acttccttac catcggcaga agtgctcaca gagtagaagt
    28381 tgctacgatg tccattgacg cccttagtaa tgacttgtgt ttttcctttg agtaagagtg
    28441 gattttcacg agtcactgtg gtaaatggaa tttcttcttt ttggatatcc agtctaggtt
    28501 ttacctcagt agttggtgca agaccacttt catcaccctt gtgagttaca ggagcgccaa
    28561 cttcaaccac ttggtttata acttctttgg ttacctggct atcaaggact gtttctgttg
    28621 tttttccatt ttcagtgagt acagagatgt aatgagttcg ttcacctttg actcctgctg
    28681 tgataatatt ttcctgacca gctgggaggt taggattttc tttcttgata acttcaaatg
    28741 gaatttcttc agttcttgtg atgagttctg gtctggtttc aacattggca gccacttcat
    28801 tttcatctag gcttcctgaa tgagttgcag ctggtttgag gccttgaaga gcggctttta
    28861 ggttggctac aagtgtgtca agctcagctt gtttattacg gttgaggttg taatttagag
    28921 ctgttttagc tgcgtcaagg gcctcaagac tttctttact atatccttct aagtttgtag
    28981 gaattttagc taattcttcg cggagagcat tataattagc acggaagtag tctttgttgt
    29041 ggtctgcaaa ggcagtcatg agttcaaaga tttcctcttc cttgtactca gcgcttggtc
    29101 tatctgccca gattgaaagc atacttccga ctgttggaag atctacttca ggatatttgg
    29161 tagaagctag ttgattgaat ggtgtttttc cagtattctc aatagctttc ttgaggaaac
    29221 caccaccatc ttctggtttt tgaccaagaa tgtagtacca gtcaccgttg gtattcaaga
    29281 atttatagcc tttgcttgct aggtattgag gtgatgcgag gttatatccc caccagcctt
    29341 tagaccagta agaaatcaag acatctttgt caaactgaac atcgtccttg tcttcatagt
    29401 agaagccatc gttgaaggcc attggttgaa gccctctttc tttggccata gctgcgaggg
    29461 tgttggcata ttcggcaaat ttgccataga gttgatacca cttgaggtag taccagcctt
    29521 gggcactagt cgcatcgttg gcgtattcgt cagtaccaaa gttgaaaatc tttgttttac
    29581 ctgcaaagaa gtccatgtat ttaccgatga gggcttttac aaagttcatc gcttcttcgt
    29641 tttttaagtc catagttgtt tttgaaactt tatcaaagtg ggcttgagga tttttaatac
    29701 ctaatttttc catggcaacc agcatagcat ccatgtgacc tggactgtta atagctggga
    29761 tgagaccgat gtccttagat ttagcgtatt caattagctc tgttacttct gcctgtgtta
    29821 gtgcagtacc gtttggatcg tcgtagtaag ctttagttcc ttcgataata gcttttttaa
    29881 cgtcatcact agcataggtt tttccgttgg cagtaatggt catatcatcg agtagaaagc
    29941 gaagtccgtc atttcctaga aggagatgga catcagaata tccgagctca ctggccttgt
    30001 ctacgatgcg tttgagctgg ttcagagtaa agtatttgcg tccagcatcg attgagatta
    30061 ccttgttttt ggcaagtttt tcaacctcac gtttagcttc ttcttctttt agagcttcag
    30121 gcgtgagggt caagttgttg acagtttctt gaagtttagc aatggcttga tcaatcgtat
    30181 cttgttgggc acggctaagg ttgctatcga gagagcgaat agctttttca gcttctttta
    30241 cggccgcgac gctttctgca gtataacggt tcaggtcttt tggtacctcg ttaagtgttt
    30301 gctctgcaga ttcataatca gctgcgaagt attcagcgtt ggcatttgca aaatgacgca
    30361 tgagtttgaa gaggcgtgat ggtgaataac gtgcagatgg agtgtcagcc caagcagcta
    30421 ccataccacc gatgattggg atatcagctc cttctgtttt tggtacagaa gtgattggtg
    30481 tgtttttaat accattgagc ccctgatcga gattgtacca gccttggcca tcagcgtttc
    30541 gtccaagaac gtagtaccaa gcatcattgg tattaaggat ttggtgacct ttttcagcta
    30601 gtagtttaga agaagcgaca tcgtagcctc cccaaccacc agtccacata gaaacgatga
    30661 tgtctttgtc aaaactacca aagcttgtgt cgctattgta gtagataccg tcgttaaaag
    30721 ccattggttt gagaccgtgc gattttacaa tacgagcgag gtcattggcg taggcaataa
    30781 atttttcata gccttttaca gggtagcctt cgtttggata gtatttatca gcttgaagca
    30841 cactccaacc tttagcatct gtcgcatcat tggcatattc atcaagtccg atgttgaaga
    30901 tttcagtctt tttcgcgaaa taagcagcat acttgtcgat aagggctttt gtaaaagcga
    30961 cagcttgttc gttgtcaaga tcgacagtac gggctgattt cttcccaaaa tagctaaagt
    31021 tagggttttg gattcccaat tctttcatgg cattgagaat cgcatccatg tgtccaggac
    31081 tatttactgt cggaatgaga ccgatacctt tatctttggc atagttaatc agatctgtca
    31141 tttgactttc tgttaagtga ttgccgtttg gatcgttgta ataatcattt gtaccttttt
    31201 caatggcgcg tttgacatcg tcactggcat aggtcttgcc gttagctgtg atgctcatat
    31261 cgtccaacat gaaacggagt ccatcatttc cgactaatag gtgtaaatca gtgtagccat
    31321 aatgtttcgc tttatcgatg atttccttga gttgttctgg tgagaaatat ttacgtccag
    31381 catcaataga aacaattttc tttttcgcta gtttttcatt tacagttgca gcacgttcct
    31441 ttcctgcctc tgtttccggt ttgtcagcct ctgctttcgc ttcatctttt ttagctggtt
    31501 tatccttgtc agtcttgtct gtatttgact ctttagaatc aacctctttc gcttcttcct
    31561 ttttaggact agcttcttct gcctttttat tagcagtttc tttttcagca gaagttggag
    31621 ttaccacttc tgctttatca ctaggagttg aactaacttc ctcttgtggt ttttcttctg
    31681 tttttggaag actagctacc ttatcagtag ctggagtttc tgtttctaca gtttttggag
    31741 cttctggttg aagcactgct ttaggtgttt cctcagtccg attttcggat gattgagggg
    31801 aatcagaaac cgtatggatg gtcggttggt tttctgtagt agtaggagta actccatcgg
    31861 ctgcaacagt ctgtgcttgg aaggcaaatc caattagaac agaagctgct cctacagcgt
    31921 atttacgaat agaaaaacgc tgttgttttt catgtttcat tgcaaaacct cctgattgca
    31981 ttgttatatt gatagcgatt atataaatca acgcctttat tttatttctt atattaacga
    32041 gagtcaagag gagatgacaa aaaactataa taagtataaa aaaatataaa atttaaactt
    32101 aagatttcag attggtcgga aaaaatgaat atatatatct agtataattt ttggttctat
    32161 ttctataaaa tattccacaa attatagaat cttccaaaaa taggtaagcg ctaccttttt
    32221 ggtgtggtat aataagcata gaaaaagccc aagcgattag ctcaggcttt cttcttagtg
    32281 atcacggtca catgagataa atttaatctt gtagtaatca gatcgtttgt aagtttcact
    32341 gtattctaaa acttggccag ttgattcgag tttggtgatt ttagtttgta ggacagtagg
    32401 gaattgttca tcgactccga ggactgaagc cgcatgttct ggagttggaa agactatttc
    32461 gttgatttct tcaaagtgtt catcattcat gtgaatgtgg tagtctaact tgaaacgatt
    32521 atagatagaa ctatagtatt caaggtttgg ataatttgcg ttgatatatt gttctgggat
    32581 gtaggatgta tggtagatat aaacgacacc gtttgattcg cggatacgtt caatcttgta
    32641 gtagaattga tcgccgcgta gacccaattt ttccaagtaa acaagcttgt ttccgcgttc
    32701 aattgaaaga acagttacct tatcatcttt agcattgaag agttcaatgt ctgaaaactc
    32761 tacaagcttg tgtttgcgcg cacgtgaaac gaaggttcct tttccttgtt ggcggacaat
    32821 atagccatct ttggcaaggt cgtttaaggc gcgaacaact gtgatagagc tgacatcgta
    32881 cattgaaatg agttctgctt cagtgtaaaa tttatctcca ctgctaaact gcccagagat
    32941 gattttattt tttaattcgt cttttatgta ttgatatttg ggaattgcca tatttttacc
    33001 tctattttcc ttctccatag aaaattttac cataaaagcg aaaaaaatag tagtcttttg
    33061 aataaaaaat tagaataata gtttgaaaaa ttaagcgata tagggattgc tcatatttta
    33121 taaatgtatt ctatacaaaa ttattttagg tcctatattc cgaatttaaa gagcgtttga
    33181 aatgggtcta aaaatgtttg aaactaattg aatgtgtgta taatagtaaa aatgcagtaa
    33241 atatcccgac aatttctatt gacaattcaa acagattggt ttataattaa tataacaaca
    33301 agtgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt gagatacgag
    33361 atgatttcta tctcgatgga aaatcattta agattttatc tggtgccatt cattatttta
    33421 gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt ggttttaata
    33481 cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag tttcattttg
    33541 aaggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt ctctacgcaa
    33601 ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta ccagcttggc
    33661 tcttgaccaa gaacatgcga attcgctcat ccgacccaac atatatcgag gcagttggtc
    33721 gctactatga tcagttattg ccaagactgg ttcctcgttt gttggacaat ggtggcaata
    33781 ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag gcttacctga
    33841 gagcgattcg acagctaatg gaagagtgtg gcgtaacctg tcccctcttt acatcagatg
    33901 gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc tttgtaacag
    33961 gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc tttgatgaac
    34021 atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttt aatcgctgga
    34081 aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga gaggttttgg
    34141 aacaaggctc tatcaatctt tacatgttcc acggtggtac aaactttggt ttcatgaatg
    34201 gttgctcagc tcgaggaact ttggacctgc cacaagttac gtcttatgat tacgatgccc
    34261 ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag atgatggcaa
    34321 cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg gagttggatg
    34381 ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg tcaagtcctg
    34441 tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc tacctacttt
    34501 atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt gatggtcgag
    34561 atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag acagagattg
    34621 gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat atcttgatag
    34681 aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa cgtaagggaa
    34741 ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac tatccactcc
    34801 cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga caaccagcct
    34861 tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac ttgtctgagt
    34921 ttggtaaggg ggttgccttt gtcaatgggc agaatctagg acgtttttgg aacgttggcc
    34981 caactctctc actttatatc cctcatagct atctcaagga aggtgccaac cgcatcatta
    35041 tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa cctacactaa
    35101 aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg gacgtttgat
    35161 ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca ttatggttgt
    35221 agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg cgacaccacc
    35281 aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc ttgctggcaa
    35341 atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc ttggtttggt
    35401 agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa caccagaaac
    35461 tcgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact tccacaaact
    35521 ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa tttcagactt
    35581 tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc attgttatga tacaatggtg
    35641 gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt tgacgatcgt
    35701 ttcatctgca ggttcccctg tatttgctgg tttcattact ggtttaatca tgggagatgt
    35761 gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg ttggtacctt
    35821 cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag ccttctctgt
    35881 ttcacaagga attgatgcac cgcttgcaat tactacaatc gctgtaccag tagcagctct
    35941 cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc accgtgtgga
    36001 tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc ttggtgcgat
    36061 tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg gtggtgcctt
    36121 tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg gcttgacact
    36181 cgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc ttccagttaa
    36241 acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga ctgttcttta
    36301 ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc ttcctgctga
    36361 agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga ttggtatttc
    36421 tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag tagctgtagc
    36481 agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct aattacaaac
    36541 ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc caattaggtt
    36601 ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttgcct cagttgcgta
    36661 aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat actcaattct
    36721 tcaatacttc accattcttc cataccatta tcgctggttt tgaccttgcc atggaagaaa
    36781 aagatggtgt aggttcaaaa gacgccgtta acggtatcaa gacaggtttg atgggaccat
    36841 tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg gggtcagtcg
    36901 cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt gcagttgcag
    36961 tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa ggggttaacc
    37021 ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct gtacttggtg
    37081 tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct tacaagttgc
    37141 caatcggtga aaagatgatt gatttccaag acatcttgaa tcaaatcttc ccacgtttgc
    37201 ttccagcaat ctttactgcc tttatcttct ggttgcttgg taagaaaggt atgaactcta
    37261 ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt ggtcactttg
    37321 cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat ggtcgcttct
    37381 gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac atttacacag
    37441 tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa gctgttattg
    37501 aaggattgga tgatttccta gtctttgcgg atcttctcgg tgggacacct tgtaatgtgg
    37561 tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg aatcttccaa
    37621 tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac aagagccgtg
    37681 ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg cttcgatgat gacgaagatg
    37741 aataatactc ttcgaaaatc tcttcaaact acgtcaacgt cgccttgccg taggtatatg
    37801 ttactgactt cgtcagtctt atccggcaac ctcaaagcag tgctttgagc agcctgcggc
    37861 tagtttccta cagattttag ttggaactcg attcaattca tgtgacaacg tgaaaatcgt
    37921 tagagcattt tatatagaat atacatggga atgtagctta ctcccattcc catatttaat
    37981 agaaaaagag gaactcaatg ctacattata caaaagaaga cttgctcgaa ttgggtgcag
    38041 aaatcactac gcgtgaaatc taccaacagc ctgatgtatg gagagaagct tttgaatttt
    38101 atcaagcaaa acgtgaagaa attgcagcct tcctacaaga aatcgctgat aaacatgact
    38161 atattaaggt tatcttgaca ggtgctggga cttctgctta tgtgggagat accttgctac
    38221 cttattttaa ggaagtctat gacgaacgca aatggaattt caatgctatt gcgacaacag
    38281 atatcgttgc caatccagca acctatttga aaaaagatgt ggcaactgtc cttgtgtctt
    38341 ttgctcgtag tgggaattcg cctgaaagtt tggcgactgt tgatttggcc aaatccttgg
    38401 tggatgagct ttatcaagtg acgattactt gtgcagcaga tggtaaattg gctcttcaag
    38461 ctcacggtga tgatcgtaat ctcttgctct tgcaaccagc tgtctctaat gatgctggat
    38521 ttgccatgac ttctagcttt acgtctatga tgttgacaac tctcttggtc tttgatccta
    38581 cagaatttgc tgttaagtct gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt
    38641 tagacaaggc agaagatgtc aaagagctcg ttgatttaga ctttaaccgt gtcatctatc
    38701 taggcgctgg tcctttcttt ggacttgctc atgaagctca gctcaagatt ttggaattaa
    38761 ctgctggtca agttgcgacc atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat
    38821 ctcttatcaa cgacaataca gttgttttgg tctttggtac aacgacagac tacactcgta
    38881 agtacgactt ggacttggtt cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc
    38941 ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga agtggccctt ggttgtggcg
    39001 gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa ctctttgctt
    39061 tattgacttc actcaaggta gaaaataaac cagatacacc gtctcctaca ggtacagtaa
    39121 accgtgtagt acaaggtgtc ataattcacg aatatcaaaa gtaagacagt gtttatgaat
    39181 tcttgacaag aggatttgta aattatcaga taaaccatag attgtcagta cgctttctat
    39241 ggtttgtttg cttgagagaa atagtaaaag gagaacagaa tgaaagcata cacagagcgt
    39301 gtatttggaa atgttgaggg tgaggatgtc ttggcctatc gatttgagac agacggtggc
    39361 taccaacttg aggttatgac ttatggtgcg actatcttgc gctatgtcgc acctgacaag
    39421 gctggaaatt ttgccaatgt tatcttggga tttgatgact ttgatagtta tgtaggcaat
    39481 agtcccaagc atggagcaag tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt
    39541 gagctcaatg gtaagaccta tgaccttgag gttaataatg ctagcaactg taatcacagt
    39601 ggttcaactg gttgggattc cagcttgttt gaagttgaag aagtaagcga tcatggcttg
    39661 actctctaca cagagcgtac agatgggaca ggagggttcc ctggaaatct caagatttgg
    39721 atcagttatc acttggaaga aactggtgcc tatgaaatca gctacaaggt aacgaccgat
    39781 caggatacgc tggtcaatcc aaccaaccac agctatttca acttgtctgg tgatttcacg
    39841 cagacgattg accgtcatgt cttccaacta aacacagagg gcatttactc aatcgctcct
    39901 gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca cgtctacaat
    39961 ggtaccttgt tgaaggatat ctttgcagaa gaagatgagc aaatccagct ggcatcaggt
    40021 ttggatcatc catttgccct tcctgcaggc catgacaatg ctggattcct ttatgaccaa
    40081 aattcaggtc gcttcctgct tttcaagaca gaagctcctt gctttgtggt ctacacagca
    40141 aactttgtgg atgaaagtgt catcatagga ggtcagccaa tgctacagca caatgggatt
    40201 gctcttgaag cgcaagcttt accagatgcc attcacagtg accttaaagg ccaagtcatt
    40261 cttaaagctg gtcaaacctt caccagtaag acacgttatg aacttgttgt gaaataaaaa
    40321 aagctggtca aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt
    40381 gataatatgc gttttattat gaaatgattt actttatatt atcctgaaat ggtgttattt
    40441 ttgagttatc tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat
    40501 tacaactaga aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca
    40561 gagacagctt taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt
    40621 ggtttagaaa tattatctca aactgagaca gagtccattc taggccttgg tggaaaagtc
    40681 ttggtacagc tgattcaagc acaagagagc ggagaagtga gggaatatta tggtctttac
    40741 catttggcca ttctcttgcc cacacgcaag gctttagctg atgtcttgaa acgcctgaca
    40801 gatttacaaa ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg
    40861 gaagatttgg agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat
    40921 attcgagaag atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat
    40981 gagttggggg aaagagtaga gccctttatc ctggcagaag gtacaagaat ggggcatatt
    41041 catctttccg tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta
    41101 gagaataaat tcagtgtgcc tggcgctagt tggattgcgg ctggagatta ccatcatcat
    41161 ttagcagtta acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt
    41221 ttagcctact atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga
    41281 gcacaagaag ttgacgcacc aatcaaatgg atgacatcga tccaattgga aatcacagac
    41341 tcagatggca tcgtgacccg tattcgttta gcaaggtaaa attaggaatt tttaataagt
    41401 tataagtatt gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagaattt
    41461 tgacaaagaa gctgattaga gatataatga agaaaaatcg agcaaggaaa aagaactgac
    41521 aaattcaaag tatattactt gtttgaaacg ttcagagggc cagttgtgtg ggattcaaaa
    41581 gatgattgaa ggagatcgtg actgtgctga tattgtgacg caactgacag cagtgaaatc
    41641 tagtgtagag cgcgtgattg agatgataat taccgaaaat cttactgaat gtatcaatca
    41701 gcccctagat gattctgaag ctcaaaagga acgcctagaa aaggctatcc gatacttgat
    41761 taaacggaaa taaatgaatg ttttgagacg atatgtgcaa aggtctatta actattagaa
    41821 tagtttaatg tgagtcaaaa gaagttgtaa aaaatcttta aaattaaaaa aacgcatagt
    41881 atcaggtgtt gaatgtactg acccccaaaa gttagatttt ttctgtctaa cttttggggt
    41941 gcagttcata agaaccttgg taatatgcgt tttattatgt agagacttat actcttcgaa
    42001 aatctcttca aaccacgtca gcttcacctt gccgtagata tggttactga cttcgtcagt
    42061 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttccat ccacaacctt
    42121 aaaacagtgt tttgagcagc ctgcggctaa cttcctagtt tgcactttga ttttcattga
    42181 gtattacttc atcttttcct gaaattgagt ttttgcccaa ctcctcttga ttattctact
    42241 tgaccgggcc aagcattcat accaccttct acgttggtaa cggtgaggcc ttgggagctg
    42301 agaaactggc aggtagatgc agagcggact cctccttgac aaatgacata gtattcatgg
    42361 tcaggtttga gttctttgta gccttgctct aaggtactta atggaagatt tttggcacct
    42421 ggtgcatgtc ctgcttggaa ttcatgtgct tcacggacat cgataagttc tagattttca
    42481 ttttggtatt ttccataaaa gtcagccatg ctgatactag tttccatatt ctactccttc
    42541 tgggttaacc attttgtata gtgaataagc gccgtcaagg ttttgggcgg taaatcctgc
    42601 ttgcttgagg ataggctctg cgatatagct gcgcaaacca ctgtggcagc tgacgatgta
    42661 ggcttgtttt ttgtccagtt catcagtttc ctccttgaca ctttgtcagt ttttgataca
    42721 atagtacaaa attagaggag gcaggctatg attcagaaac atgcgattcc tattttagag
    42781 tttgatgaca atcctcaggc ggttatcatg cccaatcacg aggggctgga cttgcagttg
    42841 ccaaagaagt gtgtttatgc atttttaggt gaggagattg accgctatgc aagggaagta
    42901 ggggcggatt gtgtcggcga attcgtttct gctaccaaga cctatccagt ctatgtcatc
    42961 aactacaagg gtgaggaggt ctgtctggct caggctcctg ttggctccgc tccagcagcc
    43021 cagtttatgg attggttgat tggctatggt gtggagcaga ttatctctac tgggacctgt
    43081 ggtgtcctag ctgatataga ggaaaatgcc tttctagtcc ctgttcgcgc tttgcgagat
    43141 gagggagcca gttaccacta tgtggcacct tgtcgttata tggaaatgca gccagaggct
    43201 attgctgcta ttgaggaagt tttggaagac agagggattc cttatgaaga agtcatgacc
    43261 tggacgacag acggttttta ccgagaaacg gctgaaaagg tggcttatcg taaggaagaa
    43321 ggctgtgctg ttgtggagat ggagtgttct gctcttgcgg cagtagctca attgcgtggg
    43381 gttctctggg gtgaattgtt gttcacagca gattctctag cggacttgga ccagtacgac
    43441 agtcgtgact ggggctcgga agcttttaat aaggcgctag aactgagttt agcaagtgtt
    43501 caccaccttt agttgtactg gcaaaggatt tgttttatca taaaatgtct agctcatact
    43561 tttcaaaaat atgtttaaac gaggtcacct tcctcttgtc ctaggcatgt tgaggttggg
    43621 aaaaatcttt aaaatcagaa aaacgtatca tatcaggtga tgaaaacttt gatactatgc
    43681 gttttatgtt ggtaagattt agagtgagat gaaatgatac tcttcgaaaa tcttttcaaa
    43741 ccaggtcagc ttcaccttgc cgtatagatg ttactgactt cgtcagttct atctgcaacc
    43801 tcaaaacagt gttttgagct gacttcgtca gttctatcca caacctcaaa acagtgtttt
    43861 gagcaacctg tgactagctt tctaagcgat gccttggttc tcattgccta taatcaaaaa
    43921 gagaaatttt ctcctgaaaa gcatatagag tagctggcgt taaaagctcc tgtcttgctt
    43981 ttttgaccta tagtcacatc tatcaagtat tgttcttgcc taagctatca ataaaaaggt
    44041 ggcatttttt aggcttggtg ttagtgaatt ttgccttatc ctatctaagt catttcgagc
    44101 tttttatggt acaatggaaa catgttattc aaattatcta aggaaaaaat agagctaggc
    44161 ttatctcgtt tatcgccagc ccgtcgtatt tttttgagtt ttgccttggt cattttacta
    44221 ggatctcttc ttttgagctt gccctttgtc caagttgaaa gctcacgagc gacttatttt
    44281 gatcatcttt tcactgctgt ctctgcagtc tgtgtgacag gtctctcaac ccttccagta
    44341 gctcacacct ataatatatg gggccaaata atctgtttgc tcttgattca gatcggtggt
    44401 ctagggctca tgacctttat tggggttttc tatatccaga gcaagcaaaa gcttagtctt
    44461 cgtagccgtg caactattca ggatagtttt agttatggag aaactcgatc tttgagaaag
    44521 tttgtctatt ctatttttct cacgaccttt ttggttgaga gcttgggagc tattttgctt
    44581 agttttcgcc ttattcctca acttggctgg ggacgtggtc tttttagttc catttttcta
    44641 gcgatctcag ccttctgtaa tgccggtttt gataatttag ggagcaccag tttatttgct
    44701 tttcagaccg atttactggt caatctggtg attgcaggct tgattattac aggcggcctt
    44761 ggttttatgg tctggtttga tttggctggt catgtaggaa gaaagaaaaa aggacgtctg
    44821 cactttcata cgaagcttgt actattgttg actataggtt tgttgttatt tggaacggca
    44881 actactctct ttcttgagtg gaacaatgct ggaacgattg gcaatctccc tgttgccgat
    44941 aaggttttag ttagcttttt tcaaacagtg acgatgcgaa cagctggctt ttctacgata
    45001 gattatactc aggctcatcc tgtgactctt ttgatttata tcttacagat gtttctaggt
    45061 ggggcacctg gaggaacagc tgggggactc aagattacga cattttttgt cctcttggtc
    45121 tttgcacgaa gtgagcttct aggcttgcct catgccaatg ttgcgagacg aacgattgcg
    45181 ccgcgaacgg ttcaaaaatc ctttagtgtc tttattatct ttttgatgag cttcttgata
    45241 ggattgattc tgctagggat aacagccaaa ggcaatcctc cctttatcca cctcatattt
    45301 gaaaccattt cagctcttag tacagttggt gtaacggcaa atctgactcc tgaccttggg
    45361 aaattggctc tcagtgttat catgccactt atgtttatgg gacgaattgg tcccttgacc
    45421 ttgtttgtta gcttggcaga ttaccatcca gaaaagaaag atatgattca ctatatgaaa
    45481 gcagatatta gtattggtta agaaaggaaa gagcatgtca gatcgtacga ttggaatttt
    45541 gggcttggga atttttggga gcagtgtcct agctgcccta gccaagcagg atatgaatat
    45601 tatcgctatt gatgaccacg cagagcgcat caatcagttt gagccagttt tggcgcgtgg
    45661 agtgattggt gacatcacag atgaagaatt attgagatca gcagggattg atacctgcga
    45721 taccgttgta gtcgcgacag gtgaaaatct ggagtcgagt gtgcttgcgg ttatgcactg
    45781 taagagtttg ggggtaccga ctgttattgc taaggtcaaa agtcagaccg ctaagaaagt
    45841 gctagaaaag attggagctg actcggttat ctcgccagag tacgaaatgg ggcagtctct
    45901 agcacagacc attcttttcc ataatagtgt tgatgtcttt cagttggata aaaatgtgtc
    45961 tatcgtggag atgaaaattc ctcagtcttg ggcaggtcaa agtctgagta aattagacct
    46021 ccgtggcaag tacaatctga atattttggg tttccgagag caggaaaatt ccccattgga
    46081 tgttgaattt ggaccagatg acctcttgaa agcagatacc tatattttgg cagtcatcaa
    46141 caaccagtat ttggataccc tagtagcatt gaattcgtaa agagggatga cccctctttt
    46201 ttgatgccca agatggcaaa tagagacaga agccccttgt cttctagtaa aagttcttca
    46261 aaggctggac tttatggtaa aatagaagga agtgacaaga gagagtaata ctcaatgaaa
    46321 atcaaagatc aaactaggaa actagctgcg ggctgctcaa aacactgttt tgaggttgtg
    46381 gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgcagatag aactgacgaa
    46441 gtcagctcaa aacactgttt tgaggttgca gatagaactg acgaagtcag taacatctat
    46501 acggcaaggc gacgttgacg tggtttgaag agatttttga agagtataag aaaaaatcag
    46561 tcccctaaag gagtagatta tgaagttatt gtctatcgcc attcccagct ataatgcagc
    46621 agcctatctt cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt
    46681 gattatcaat gacgggtctc aggatcagac tcaggaaatc gctgagtgtt tagctagcaa
    46741 gtatcctaat atcgttagag ccatctatca ggaaaataaa tgccatggcg gtgcggtcaa
    46801 tcgtggcttg gcagaggctt ctgggcgcta ttttaaagta gttgacagtg atgactgggt
    46861 ggatcctcgt gcctacttga aaattcttga aaccttgcag gaacttgaga gcaaaggtca
    46921 agaggtggat gtctttgtga ccaattttgt ctatgaaaag gaagggcagt ctcgtaagaa
    46981 gagtatgagt tacgattcag tcttgcctgt tcggcagatt tttggctggg accaggtcgg
    47041 aaatttctcc aaaggccagt ataccatgat gcactcgctg atttatcgga cagatttgtt
    47101 gcgtgctagc cagttctaac tgcctgaaca tactttttat gtcgataatc tctttgtctt
    47161 tacgcccctt cagcaggtca agaccatgta ctatctgcct gtcgatttct atcgttattt
    47221 gattgggcgt gaggaccagt ctgtcaatga gcaagtgatg attaagtgca ttgaccagca
    47281 actcaaggtc aatcgactct tggtagacca acttgatttg tcccaagtga gtcatcccaa
    47341 aatgcgagaa tatctgctga atcatattga aatcacgacg gtgatttcca gtaccctgct
    47401 caaccgatct ggaacaacgg agcatctggc aaaaaaacgc caattgtgga cctatattca
    47461 gcagaaaaat ccagaagtct ttcaggctat tcgtaagacc atgttgagcc gtttgaccaa
    47521 acattctgtc ttgccagatc gcaaactgtc caatgtcgtc tatcaaatca ccaaatctgt
    47581 ttatggattt aattaatata agtgttttat aagagggatt taagaaaaat tttaactttt
    47641 tcttagtcct ttttaatttc aggagattat actagagtca tcaaataaag aaagactcta
    47701 aggagaatcc tatgaaattc aatccaaatc aaagatatac tcgttggtct attcgccgtc
    47761 tcagtgtcgg tgttgcctca gttgttgtgg ctagtggctt ctttgtccta gttggtcagc
    47821 caagttctgt acgtgccgat gtggtcaatc cgaccccagg tcaagtctta cctgaagaga
    47881 catcgggaac gaaagagggt gacttatcag aaaaaccagg agacaccgtt ctcactcaag
    47941 cgaaacctga gggcgttact ggaaatacga attcacttcc gacacctaca gaaagaactg
    48001 aagtgagcga ggaaacaaac tcttctagtc tggatacact ttttgaaaaa gatgaagaag
    48061 ctcaaaaaaa tccagagcta acagatgtct taaaagaaac tgtagataca gctgatgtgg
    48121 atgggacaca agcaagtcca gcagaaacta ctcctgaaca agtaaaaggt ggagtgaaag
    48181 aaaatacaaa agacagcatc gatgttcctg ctgcttatct tgaaaaagct gaagggaaag
    48241 gtcctttcac tgccggtgta aaccaagtaa ttccttatga actattcgct ggtgatggta
    48301 tgttaactcg tctattacta aaagcttcgg ataatgctcc ttggtctgac aatggtactg
    48361 ctaaaaatcc tgctttacct cctcttgaag gattaacaaa agggaaatac ttctatgaag
    48421 tagacttaaa tggcaatact gttggtaaac aaggtcaagc tttaattgat caacttcgcg
    48481 ctaatggtac tcaaacttat aaagctactg ttaaagttta cggaaataaa gacggtaaag
    48541 ctgacttgac taatctagtt gctactaaaa atgtagacat caacatcaat ggattagttg
    48601 ctaaagaaac tgtcgaaaaa gccgttgcag acaacgttaa ggacagtatc gatgttccag
    48661 cagcctactt agaaaaagcc aagggtgaag gtccattcac agcaggtgtc aaccatgtga
    48721 ttccatacga actcttcgca ggtgatggta tgttgactcg tctcttgctc aaggcatctg
    48781 acaaggcacc atggtcagat aacggcgacg ctaaaaaccc agctctatct ccactaggtg
    48841 aaaacgtgaa gaccaaaggt caatacttct atcaattagc cttggacgga aatgtagctg
    48901 gcaaagaaaa acaagcgctc attgaccagt tccgagcaaa tggtactcaa acttacagcg
    48961 ctacagtcaa tgtctatggt aacaaagacg gtaaaccaga tttggacaac atcgtagcaa
    49021 ctaaaaaagt cactattaag ataaatgtta aagaaacatc agacacagca aatggttcat
    49081 tatcaccttc taactctggt tctggcgtga ctccgatgaa tcacaatcat gctacaggta
    49141 ctacagatag catgcctgct gacaccatga caagttctac caacacgatg gcaggtgaaa
    49201 acatggctgc ttctgctaac aagatgtctg atacgatgat gtcagaggat aaagctatgc
    49261 taccaaatac tggtgagact caaacatcaa tggcaagtat tggtttcctt gggcttgcgc
    49321 ttgcaggttt actcggtggt ctaggtttga aaaacaaaaa agaagaaaac taatcagcta
    49381 aggaaataaa tgatggatag tgggctgact aagattagtt taacaactca atcagcaatc
    49441 aggactttct ttcaatagca gattaaaatc atcgtaaaac aataaaaata gtgttatact
    49501 taaagcagta tagcactgtt tttatcaaag gagagacaga tgggaaagac aattttactc
    49561 gttgacgacg aggtagaaat cacagatatt catcagagat acttaattca ggcaggttat
    49621 caggtcttgg tagcccatga tggactggaa gcgctagagc tgttcaagaa aaaaccgatt
    49681 gatttgatta tcacagatgt catgatgcct cggatggatg gttatgattt aatcagtgag
    49741 gttcaatact tatcaccaga gcagcctttc ctatttatta ctgctaagac cagtgaacag
    49801 gacaagattt acggcctgag cttgggagca gatgatttta ttgctaagcc ttttagccca
    49861 cgtgagctgg ttttgcgtgt ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca
    49921 gagctgattt cccttggcaa tctaaaaatg aatcatagta gtcatgaagt tcaaatagga
    49981 gaagaaatgc tggatttaac tgttaaatca tttgaattgc tgtggatttt agctagcaat
    50041 ccagagcgag ttttctccaa gacagacctc tatgaaaaga tctggaaaga agactacgtg
    50101 gatgacacca ataccttgaa tgtgcatatc catgctcttc gacaggagct ggcaaaatat
    50161 agtagtgacc aaactcccac tattaagaca gtttgggggt tgggatataa gatagagaaa
    50221 ccgagaggac aaatatgaaa ctaaaaagtt atattttggt tggatatatt atttcaaccc
    50281 tcttaaccat tttggttgtt ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga
    50341 tttacttttt gcttgggatg accatcgttg ccagccttgt cggtgctggg attagtctct
    50401 ttctcctatt gccagtcttt acgtcgttgg gcaaactcaa ggagcatacc aagcgggtag
    50461 cggccaagga ttttccttca aatttggagg ttcaaggtcc tgtagaattt cagcaattag
    50521 ggcaaacttt taatgagatg tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa
    50581 gcgaacgaga aaagggcttg atgattgccc agttgtcgca tgatattaag acccctatca
    50641 cttcgatcca agcgacggta gaagggattt tggatgggat tatcaaggag tcggagcaag
    50701 ctcattatct agcaaccatt ggacgccaga cggagaggct caataaattg gttgaggagt
    50761 tgaatttttt gaccctaaac acagctagaa atcagatgga aactaccagt aaagacagta
    50821 tttttctgga caagctctta attgagtgca tgagtgaatt tcagtttttg attgagcagg
    50881 agagaagaga tgtccacttg caggtaatcc cagagtctgc ccggattgag ggagattatg
    50941 ctaagctttc tcgtatcttg gtgaatctgg tcgataacgc ttttaaatat tctgctccag
    51001 gaaccaagct ggaagtggtg gctaagctgg agaagggcca gctttcaatc agtgtgaccg
    51061 atgaagggca gggcattgcc ccagaggatt tggaaaatat tttcaaacgc ctttatcgtg
    51121 tcgaaacttc gcgtaacatg aagacaggtg gtcatggatt aggacttgcg attgcgcgtg
    51181 aattggccca tcaattgggt ggggaaatca cagtcagcag ccagtacggt ctaggaagta
    51241 cctttaccct cgttctcaac ctctctggta gtgaaaataa agcctaaaac ccctttacaa
    51301 atccagctat tcatggtaaa atggaccttg tgtgaaatat cagcaggaaa gcatgaagct
    51361 cgtcaacagg tgtcttatga taagtaacct tggctgttta ggcgaagggc atctgcacga
    51421 atcagggctt tctaagtgac tatttccacc gaaatattat ttatatcagg aggacattca
    51481 tatgtcacgt tatacaggac catcttggaa acaagctcgt cgccttggcc tttcacttac
    51541 aggtacaggt aaagaattgg cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa
    51601 ccgttctaaa ttgtcagaat acggtttgca attggctgaa aaacaaaaac ttcgtttcac
    51661 ttacggtgta ggtgaaaaac aattccgtaa cttgttcgta caagctacaa aaatcaaagg
    51721 cggaatccta ggtttcaact ttatgcttct tttggaacgt cgtttggata acgttgttta
    51781 ccgtcttggt ctcgcgacta ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat
    51841 ccttgttgac gggaaacgcg ttgatatccc atcataccgc gtaactccag gtcaagtgat
    51901 ctcagttcgt gaaaaatcat tgaaagttcc agcaatcctt gaagcagtag aagctactct
    51961 tggacgtcca gcattcgtat cattcgacgc tgaaaagttg gaaggttcat tgactcgctt
    52021 gccagaacgc gacgaaatca acccagaaat caacgaagca cttgtcgttg aattctacaa
    52081 caagatgttg taatatttta ttgaataaga caggctttga ggccttgata ttaagcactt
    52141 tgggacgttc tcccttagtg cttttttgat ttctcttagt atccagctat aatcgtttag
    52201 acataactag accgatatag tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca
    52261 atgtggtata atcttttta
//
LOCUS       DAVKZI010000010        52132 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKZI010000010 DAVKZI010000000
VERSION     DAVKZI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.010"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(224..586)
                     /locus_tag="VXB18_000694"
     CDS             complement(224..586)
                     /locus_tag="VXB18_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0381931.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            600..674
                     /locus_tag="VXB18_000695"
                     /pseudo
     CDS             600..674
                     /locus_tag="VXB18_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(922..1059)
                     /locus_tag="VXB18_000696"
                     /pseudo
     CDS             complement(922..1059)
                     /locus_tag="VXB18_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1437..2126)
                     /gene="rplA"
                     /locus_tag="VXB18_000697"
     CDS             complement(1437..2126)
                     /gene="rplA"
                     /locus_tag="VXB18_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0381932.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2334..2759)
                     /gene="rplK"
                     /locus_tag="VXB18_000698"
     CDS             complement(2334..2759)
                     /gene="rplK"
                     /locus_tag="VXB18_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0381933.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2891..3028
                     /locus_tag="VXB18_000699"
     CDS             2891..3028
                     /locus_tag="VXB18_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381934.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEIADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(3068..3784)
                     /locus_tag="VXB18_000700"
     CDS             complement(3068..3784)
                     /locus_tag="VXB18_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0381935.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKPKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVVNKGDYYSIQGKYDEIVIANKHYPLSKDYNPGENPTAKAELLKLI
                     AAMQAAGYPISDHYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3802..4263)
                     /locus_tag="VXB18_000701"
     CDS             complement(3802..4263)
                     /locus_tag="VXB18_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0381936.1"
                     /translation="MCLICQRIELIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMENPVKFRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     TGDMKGHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKHLA"
     gene            complement(4265..5302)
                     /locus_tag="VXB18_000702"
     CDS             complement(4265..5302)
                     /locus_tag="VXB18_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0381937.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEEHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEERIDLPMTTHFAFSVFEE
                     VGHGANSNIPKEVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATELM
                     VDAYLKSEGVS"
     gene            complement(5400..6725)
                     /gene="brnQ"
                     /locus_tag="VXB18_000703"
     CDS             complement(5400..6725)
                     /gene="brnQ"
                     /locus_tag="VXB18_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0381938.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6896..6988)
                     /locus_tag="VXB18_000704"
     CDS             complement(6896..6988)
                     /locus_tag="VXB18_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0381939.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7031..7183)
                     /locus_tag="VXB18_000705"
     CDS             complement(7031..7183)
                     /locus_tag="VXB18_000705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0381940.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7343..7921)
                     /locus_tag="VXB18_000706"
     CDS             complement(7343..7921)
                     /locus_tag="VXB18_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0381941.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7975..9375)
                     /gene="pepV"
                     /locus_tag="VXB18_000707"
     CDS             complement(7975..9375)
                     /gene="pepV"
                     /locus_tag="VXB18_000707"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0381942.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSSWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9388..9993)
                     /locus_tag="VXB18_000708"
     CDS             complement(9388..9993)
                     /locus_tag="VXB18_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0381943.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10164..10964
                     /locus_tag="VXB18_000709"
     CDS             10164..10964
                     /locus_tag="VXB18_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0381944.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNTLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11146..11979)
                     /locus_tag="VXB18_000710"
     CDS             complement(11146..11979)
                     /locus_tag="VXB18_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0381945.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKDQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGEYGLEHPQEIQLMRMTQFLMERMDPE
                     TIVWLRSLPLLEKKEVDGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11969..13813)
                     /gene="uvrC"
                     /locus_tag="VXB18_000711"
     CDS             complement(11969..13813)
                     /gene="uvrC"
                     /locus_tag="VXB18_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0381946.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNSPSKVCF
                     YYHIGQCMAHTICKKDEVYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDQEAVQALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQRDGLTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVELSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13877..14554)
                     /locus_tag="VXB18_000712"
     CDS             complement(13877..14554)
                     /locus_tag="VXB18_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0381947.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANL"
     gene            complement(14633..15865)
                     /gene="murN"
                     /locus_tag="VXB18_000713"
     CDS             complement(14633..15865)
                     /gene="murN"
                     /locus_tag="VXB18_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0381948.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTIGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15870..17090)
                     /gene="murM"
                     /locus_tag="VXB18_000714"
     CDS             complement(15870..17090)
                     /gene="murM"
                     /locus_tag="VXB18_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0381949.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17202..17981)
                     /locus_tag="VXB18_000715"
     CDS             complement(17202..17981)
                     /locus_tag="VXB18_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0381950.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18050..19711)
                     /locus_tag="VXB18_000716"
     CDS             complement(18050..19711)
                     /locus_tag="VXB18_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0381951.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19886..22108)
                     /gene="recJ"
                     /locus_tag="VXB18_000717"
     CDS             complement(19886..22108)
                     /gene="recJ"
                     /locus_tag="VXB18_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0381952.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22385..23143
                     /locus_tag="VXB18_000718"
     CDS             22385..23143
                     /locus_tag="VXB18_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0381953.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNIYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            23154..23948
                     /locus_tag="VXB18_000719"
     CDS             23154..23948
                     /locus_tag="VXB18_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0381954.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23961..24638
                     /locus_tag="VXB18_000720"
     CDS             23961..24638
                     /locus_tag="VXB18_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0381955.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24648..25307
                     /locus_tag="VXB18_000721"
     CDS             24648..25307
                     /locus_tag="VXB18_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0381956.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25556..26746
                     /locus_tag="VXB18_000722"
     CDS             25556..26746
                     /locus_tag="VXB18_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0381957.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKKVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27067..27948)
                     /locus_tag="VXB18_000723"
     CDS             complement(27067..27948)
                     /locus_tag="VXB18_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0381958.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28089..29417)
                     /gene="vncS"
                     /locus_tag="VXB18_000724"
     CDS             complement(28089..29417)
                     /gene="vncS"
                     /locus_tag="VXB18_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0381959.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKYYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29414..30070)
                     /gene="vncR"
                     /locus_tag="VXB18_000725"
     CDS             complement(29414..30070)
                     /gene="vncR"
                     /locus_tag="VXB18_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0381960.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDSVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30119..30202)
                     /gene="pep27"
                     /locus_tag="VXB18_000726"
     CDS             complement(30119..30202)
                     /gene="pep27"
                     /locus_tag="VXB18_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0381961.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(30382..31761)
                     /gene="vex3"
                     /locus_tag="VXB18_000727"
     CDS             complement(30382..31761)
                     /gene="vex3"
                     /locus_tag="VXB18_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0381962.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31813..32460)
                     /gene="vex2"
                     /locus_tag="VXB18_000728"
     CDS             complement(31813..32460)
                     /gene="vex2"
                     /locus_tag="VXB18_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0381963.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32473..33750)
                     /locus_tag="VXB18_000729"
     CDS             complement(32473..33750)
                     /locus_tag="VXB18_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0381964.1"
                     /translation="MNPIQRAWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGSGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(34107..34277)
                     /locus_tag="VXB18_000730"
                     /pseudo
     CDS             complement(34107..34277)
                     /locus_tag="VXB18_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34420..35019)
                     /locus_tag="VXB18_000731"
     CDS             complement(34420..35019)
                     /locus_tag="VXB18_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381965.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(35156..36040)
                     /locus_tag="VXB18_000732"
     CDS             complement(35156..36040)
                     /locus_tag="VXB18_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0381966.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(36044..36430)
                     /locus_tag="VXB18_000733"
     CDS             complement(36044..36430)
                     /locus_tag="VXB18_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0381967.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(36423..37766)
                     /locus_tag="VXB18_000734"
     CDS             complement(36423..37766)
                     /locus_tag="VXB18_000734"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0381968.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37853..38737)
                     /locus_tag="VXB18_000735"
     CDS             complement(37853..38737)
                     /locus_tag="VXB18_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381969.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38749..39366)
                     /gene="cysE"
                     /locus_tag="VXB18_000736"
     CDS             complement(38749..39366)
                     /gene="cysE"
                     /locus_tag="VXB18_000736"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0381970.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(39382..41595)
                     /gene="pnp"
                     /locus_tag="VXB18_000737"
     CDS             complement(39382..41595)
                     /gene="pnp"
                     /locus_tag="VXB18_000737"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0381971.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(42280..43146)
                     /gene="metF"
                     /locus_tag="VXB18_000738"
     CDS             complement(42280..43146)
                     /gene="metF"
                     /locus_tag="VXB18_000738"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0381972.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISITAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(43210..45459)
                     /gene="metE"
                     /locus_tag="VXB18_000739"
     CDS             complement(43210..45459)
                     /gene="metE"
                     /locus_tag="VXB18_000739"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0381973.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGFDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDTDYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45720..45986)
                     /locus_tag="VXB18_000740"
     CDS             complement(45720..45986)
                     /locus_tag="VXB18_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0381974.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            complement(46112..46515)
                     /locus_tag="VXB18_000741"
                     /pseudo
     CDS             complement(46112..46515)
                     /locus_tag="VXB18_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            46671..47672
                     /locus_tag="VXB18_000742"
     CDS             46671..47672
                     /locus_tag="VXB18_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0381975.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47740..50142)
                     /locus_tag="VXB18_000743"
     CDS             complement(47740..50142)
                     /locus_tag="VXB18_000743"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0381976.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(50219..50728)
                     /locus_tag="VXB18_000744"
     CDS             complement(50219..50728)
                     /locus_tag="VXB18_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0381977.1"
                     /translation="MIIKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50728..51774)
                     /gene="pheS"
                     /locus_tag="VXB18_000745"
     CDS             complement(50728..51774)
                     /gene="pheS"
                     /locus_tag="VXB18_000745"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0381978.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNICKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14737 a        11837 c         9826 g        15732 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaagga ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taataaaatt
      121 ttattcaatc catctactca ttcccaaaag gttgctgtat aatgcaagac atttttctta
      181 ctgattttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactatt gaaacaatag aacgtaaata atgataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatgact ataatcatct gtatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaactgatt aggaaattta aaccaacttc taacaatctg ttatactcaa
      601 tgaaaaccaa agagcaaact aggaaactag cctcaggttg ctcaaaacac tgttttgagg
      661 ttgtagatgg aactgacgta gtcagctcaa aacactgttt tgaggttgtg gatagaactg
      721 acgaagtcag taaccatacg cacggcaagg cgacgttgac gtggtttgaa gagattttcg
      781 aagagtatta gaaagctcga tggactattc cagattcatt ccactagatt tcgaaatcga
      841 gtaggggata atctctagcc cctctcacac caccgtacgt gccgttcggc atacggcggt
      901 tcaactaact gttaacgcat gtcattcaag gtaataatcc aaacacgaaa ccagtccacg
      961 tttttcaagg actggttttg atatagcacg tttaagtacc gacttctgag ctactaattg
     1021 atagtggtcg ccccagccag ataccttatc cgctatatag gccttattat cacgttcctg
     1081 ttcgtagagc cacgatttcg ctatcccttc ctctgacgat tcttatttcc agcgtcagac
     1141 ttaaaacggt ctatccccag accgttttaa tccgctacct cacgatagtc agacttggga
     1201 atcgctattg ggttcaccgg tagcaggtgc ccaccgagga cttacacctc aaatatataa
     1261 taaaatgaaa taagaatagg acgaatcgat caggacagtc aaatcaattt ctaacaatgt
     1321 tttagaagta gatgtgtact attctagttt caatctatta tacaacatgc ccgtcgtaca
     1381 tcaaaaaaag ttgagacata gcgtcttcaa cttttttaca ttactttaac tactgattaa
     1441 agtgagttta cgtcaacttt gataccaaca ccttgagtag ttgtgatagt caagtttgtt
     1501 acgtaagttc ctttagctgt agctggtttt gctttttgga ttgtttcgtt gaaagcttta
     1561 aagttttcaa ccaatttttc agcttcaaat gatactttac cgatgattgc ttgaacgtta
     1621 cctgcacggt cagcacggta agtgatttta ccacctttag actcttcaac tgctttagca
     1681 acatccattg ttacagtacc agttttaggg tttggcatca agttacgtgg tccaaggaca
     1741 cgtccaagac gtccaacaag agccatcata tcaggtgtag cgataactac gtcgaagtcc
     1801 aaccaaccgt cgttgatttt agcaacaagg tcatcttcac caacaaagtc tgcaccagca
     1861 gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa gaacacgtga agttttacca
     1921 gtaccgtttg gcaataccat tgctccacgg atttgttggt cagctttttt aacgtcgatg
     1981 ttcaagttgt aagcaacttc tacagttgca tcaaattttg caaagttagt ttcttttgca
     2041 agtgctacag cttcttctac actgtatgct tttgtgctgt cgattttctc aagagcagca
     2101 cgaagttgtt tgcttttttt agccattttc tattctcctt gtaagtggtt caatcgattt
     2161 tcatctccca cgtcacttct cgaaatgatg aagtcttgcg ggttttcagt ctactatttt
     2221 tctcttccta cggccttaag ctcccttgct gtacccaagt acaagcctca gtcacttgcc
     2281 tagtatgaaa agcaactaat agactgctgt gagattttct actgtgttat tgattagtca
     2341 acaacagtga atcccataga acgagcagta ccttcgatca tacgcattgc agactctacg
     2401 tttgctgcgt tcaaatctgg catcttagtt tctgcaattt cttgtacttg tgcacgagta
     2461 actgtagcaa ctttagtttt attaggtgta cctgatcctt tttcaacacc tgcagctttt
     2521 ttcaaaagaa cagcagctgg tggtgttttc gtaacgaaag taaatgattt atcttcgtaa
     2581 actgagataa caactggaat gatcatacca gcttggtcag ctgtacgagc gttgaactct
     2641 tttgtgaatc ccatgatgtt gataccagct tgaccaagag caggtccaac cggtggagct
     2701 ggtgtagctt taccagcagg gatttgcaat tttacaagtt tttcgacttt tttagccatt
     2761 tttaaatcct cctttgtggt tttggcggta attagagatt tttacctccc acaagtatgt
     2821 ttttcacata cccctccatt atacactatt tatctggaat tgcaagagaa aagtttattt
     2881 tttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gctcaaagta
     2941 cagctttgag attgcagata aaactgacga agtcagctca aaacactgtt ttgaggttgt
     3001 gaatagaacc gacgcagtca gtaggtaagg cgacgctgac gtggtttgaa gagattttcg
     3061 aagagtatta atcgacgtag tctccgcctt caaagccata gtactcttcc aaactgaggc
     3121 cacttgcagc aatttctttg gcttcttttc caacgtagcg gagatgccat tcttctgcca
     3181 tgtagccggt ctccttttcc ttgcctttga gatagcggac aacaaagcca tagtcagccg
     3241 catggtccaa gagccactgg gctgcctttt cttcagtaac taaatcacca tctgtcccaa
     3301 taaggtcaaa agcaaggcct gtttggtgtt cactataacc tgggcgtgct gagtagcgat
     3361 ccgctgcttc cttaccatct tgattgacat agtcttggta gagcttagcc tgagtttcat
     3421 aacttctaaa accactgtag tgatcgctga ttgggtagcc agctgcttgc attgctgcaa
     3481 tgagtttcag caactctgcc ttggctgttg gattttctcc tggattgtag tcttttgaca
     3541 aaggatagtg cttattagct atgacgattt catcgtattt cccttgaata ctatagtagt
     3601 ctcccttatt gacaacttct gcctttttct gactagatgc ttgagatttg ctacctacag
     3661 ttccttccgg ttgactgctt tgctccgtct tttgagtatt ttcttcaact ttcggttttt
     3721 cttgcgaaca agctgcaaga gtcaatgcta gtaaaccaga taaaatgaca tatctttttt
     3781 tcatttcttt cttcctctct cttaggccaa atgcttctcc aattcatgag ataagatttt
     3841 aatcatctct tccagctctg gcgattgtac ttggcaatct tctgctgcca tttcttccca
     3901 gggcacccac cagactgggc cacggccatt caatccatga cccttcatat cacctgttct
     3961 tcgtggaaag agatgccaat gagcgtgggc atcaccattt cctaggagtt caatattcat
     4021 cttttcagcc tcaaatgctt tggcgactgc ttcttggacc aaactcattt cctctaaaaa
     4081 gcgaaatttt acaggattct ccatatggtg gagttctgta acatgctctt ttgctaaaaa
     4141 taaggtatag cccttgaagt attggtgatc cccaataacc acatagcctg tttctagttc
     4201 tttaacaaag tagggatttt ctccagcttt gatgagttcg attctctgac agattaagca
     4261 cattctatga taccccctcg ctcttaagat aagcatcaac cataagctca gtcgctacta
     4321 ctgaatcgat gtgggtgcgc tcataagagt gactggactc aataccagct ccaagaagtg
     4381 catgcttgac ctccgcgcct gctgacatcg ctgctgaagc atccgaaccg taaaatggat
     4441 aaatgtcgag cttaaatgga atatcttgct ccttcgccaa agctactaag tgttgacgga
     4501 agtcatagtg ataaggacca gaagcatcct tgacacagat agatactgtg tactcattcg
     4561 tctgttggtc atcccccatt gcacccatat cgacagccag gtactctacc acctcttttg
     4621 gaatatttga attggcacca tggcccacct cttcaaagac tgaaaaggca aaatgtgtcg
     4681 tcatcggcaa gtcgattctc tcttctttat aaactcgaag gagattgagc agaattgctg
     4741 cgctgacttt gtcgtccaag tgacgggact tgataaaacc agtctctgtc acgacagtac
     4801 gtggatcaaa gctgataaaa tcaccgacct cgatgcccaa ggcacgcgtt tctttttcat
     4861 tggtcacttt ttcatccaaa cgcacttcca tattgtcctg agtgcgttca gcagttcctg
     4921 catctttgta gacatggcaa gatgtctggt ggatgaggat cgttccagat accgttttac
     4981 ctgtactagc tacatgaaca gtacagtttt ctccctcaat catgttccaa ggaaaaccac
     5041 cgatacggtc caatttgaga cgaccatctg gcttgactgc acgcacaatg gctccaagtg
     5101 tgtccacatg ggcagttaca tagcgatgtt cttcgtcgtt ttgacctttg atggtcacat
     5161 tgacaccgcc cttggctgtt cgaacaggct ggtaaccaaa accttctaga gtcttgacta
     5221 aataattcga aatttcacga gtaaagcccg ttggcgatgc gatggctgtc agttctttga
     5281 tatattctac tgtttgattc atttcttcac ctctttcgct acctattata acacatttat
     5341 catcggataa aaaaagaaaa tcactcctgt agacttggct acaaaagtga tttaagtgat
     5401 tattccattt caaaaacatc gctttcttgc ttgtttggta gaaccaatga gagcaagatt
     5461 ccaacaatgg ctggcaccaa ccatgggaga gatgccttgg caaaaggaag aacgctaaca
     5521 agatttgcaa gaaactcaac cttaaacgag cttcctagta cgcttgcaat ggcaataact
     5581 gtaaccacag caattgtcaa ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca
     5641 atgacaatca taacgatagc aatcgtgatt gggtacaaga taaccagtac tggaattgag
     5701 tacttgataa tcgcatcaag acccaaattg gcaatagcaa atccaatcaa ggtaaaggct
     5761 gtcgcataaa ccttgtagct gatttgtggg aagcgctcat taaagaactc agctgttgac
     5821 acaatcaaac caacagtcgt tgtgaagcag gttacggtaa ccatagctgc aaggaagagt
     5881 tgagctgttg agccaaagat ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt
     5941 ccacccttca tcgcttcagc tggtactggg aaatgatttc caagaaaacc taaaccgatg
     6001 taaagagcgc tgaaggcaag ggcaacaacg ataccaacaa cccaaatagt tgaaatgtat
     6061 tctttcttac ttgaaaatcc aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc
     6121 actgaggcaa gggcgtccaa ggtattgtaa ccttctagga aacctgtacc aaaggcagaa
     6181 gcttgataag cagctgaagc agcttgagga cttgttccac catatttgat agctcccaga
     6241 acgaccaaga taacaatcaa aattgcaaag actggcgtta aaatacgtcc aatgcggtct
     6301 aagatttttg atggattaag cgaaatcaaa taggctgccg caaaatacag aaccgtaaat
     6361 acaatcaagc caagtccttt atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa
     6421 gctgttgtag cagtacgtgg ggtagcaaag aatggaccga ttgacaagta aagaactgag
     6481 aggtaaagag tcgcaaacca aggcgctatc ttcgttgaaa tctcgtagat atatccttta
     6541 ggatttagcg ttccaataat aagggtcaag acggcgatac caacgcctga aaagacaaaa
     6601 cctgcgatgg caggaagaaa atgttctcca gatagagcac ctagagaagg cggaaaaatc
     6661 aagttccccg caccaaaaaa tattccaaac aggagcaaac ctgttagggt acctttttta
     6721 gccataaaaa tctccttcat atttataaaa tactgaccta gtataccacg attaggagtc
     6781 tgaaaaaagc atcacgaggc aaatattaaa tgttttcaat tttcttaaaa ataagaatta
     6841 tctaaaaata aaactctcct acccagtcca caccaagtag gagaaatgca aaattttaaa
     6901 gttcttcaaa ggctaacatg ccaccctgga cattgataac attataacct tgttctaaca
     6961 ggaattggca agcacgcgcc gatctcattc cagatttgca aataatataa tgcaagcgat
     7021 ctttgtccaa ttaatcataa ctatcagcca attgactaag cggtaggttg tgggcacctt
     7081 ctaaatgaag agctgcaaac tcatccactt ctctcacatc cactagagaa agctggtcgt
     7141 tttggtaaag ctggtaaaat gcgtcaaagg ctatttcttt cattcttttt cttctaatac
     7201 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt
     7261 cgtcagtttt atctgcaacc tcaaagctgt actttgagca gcctacgact agcttcctag
     7321 tttgctcttt gattttcatt gactataaaa tggttttaat tctttttttc aaatctggca
     7381 ctacttctgc ctcaaaccaa ggatttttgg ccatccagat ttgatttcgt ggtgatgggt
     7441 gaactagcgg aaaataggct ggcagatagt ctttatagtg tttcaccctc tccgttacct
     7501 tcccactgat tttctcctgt aaatagtagg cttgggcata ttgcccaatc aagagggtta
     7561 actgaatatc aggcaattcc tgtaagagct gcggatgcca tttttctgca aaacctgtac
     7621 gaggcggaag atcacccgac ttgccatgtc ctggaaagta gaaatccata ggcaaaacag
     7681 caaaataacc tgaattgtaa aaggtatctt catccacacc tagccagtcc cgcaagcggt
     7741 caccactttt atctttccag taaaggcctg cttcttgagt tttaagtcct ggagcctgac
     7801 cgatgatatt gatgcgagca gtttttggcg ctgcaaagag aggctcaatg ccacgctctg
     7861 tatagctggc attctgtgaa tccgccatga tagcctgttt gattctttcg atttgagaca
     7921 tctactttcc ctccaaaaag aagtccaagc ataagatctc agacttctat cgttttattt
     7981 gatcaattcg taaatagctt cggcataaat tgctgctgct cggaagagat cgtccaaggc
     8041 aataaattca ttggcttggt gcatggtatc aattgagtct gggaacatag caccataggc
     8101 aactccgcgc tctaacaagc gaccaaaggt tccaccaccg atgacttgtt catgaccttt
     8161 aaggcctgtt tgtttttcat agacattcaa caaggtttgc acaagtggat cttccattgg
     8221 cacatagtga ggggtatgac catgttctga tagactgaca gaagcaactg gcaagttttc
     8281 taggattgac ttgatttgtt ctggacttgt tccttttgga tagcggatgt taagggcaat
     8341 ggtattatca gcacttgttt catcgaagcg gaagacgccg gcattcatag aaagagcacc
     8401 catcttttca tccacatgag caatcttgag attttcaccc tcatgatcgt tcaagagaat
     8461 tttacctgcg atgtcaaggt agtctttggc tggaccagca aagccaaact ggctgaggaa
     8521 gagggctagg taagtcgcac cattgacacc tgaagcaggc atagcaccgt gggctgattt
     8581 accaatgatc gtcaccttgt atttgccagc ttcttcttgg agttctcctc taagtttgtg
     8641 ttctgcaaca aaggcatcta gtttagcttg caagtcagcc aaatcacctg aaacgactgc
     8701 tgttgctgat tctggtacca tattttcacg taaaccacct gtaaagctgt gaagacgggc
     8761 agcacctgta ttttctcctg caaagtggag gtattccgtg atatttcctt tttcaccatt
     8821 gatgattgga aattcagcat ctggtgagaa accgaaatct ggtttggcaa gtcctacgtg
     8881 ctcaaagtag tagtccatgt ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg
     8941 aactttctta gaagttggaa gacccaattc tttgatgatt ttcaaaccat agtaacaagc
     9001 tgttgtagga cccttatcgt ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt
     9061 tggtgtgtaa ggatctgtat cccaactgct accagctgga accacgtcca tatgggcaaa
     9121 gattccgaga acttcttctc catcaccaaa ctcaaaatgt cctgcatagt tatcaacatt
     9181 tttagttgga taaccatcac ggtctgcgat ttcaaggaat ttttccaagg cttttactgg
     9241 accaggtcca aatggatgtt gggcatcagc cttgctatca tcacgttctg agttgatttc
     9301 caaaaggcta aacaagtcag ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa
     9361 atcaattgct atcatttttt cttcttccta tcttttttcg atgatttcat ctactggcaa
     9421 gcggtagctt ggttccaatt tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg
     9481 gaaacggtct tcgatttcca aaacttcatt aacttttgat ttgtcaaaac caagaataat
     9541 gttagaacca attccttggt ctgtaagagc aagaaccaag ttcatggcaa ccaaacctgc
     9601 attgagagct aggtagtcgc tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa
     9661 atttttcatg aagtattgaa gttgttcttc tgagaaattg ttagcaccac caactcgggc
     9721 aatcttacga gcgcgtttgg caaggtctgt atctgtaaat agggcaatgg ttacaggtgc
     9781 tgatgatacc tgctcaaagt ttgaaccata agccaacttt gccagttcag catttttctc
     9841 acgaacaact acaaatttcc aaggctggct gttgtgggcg cttggcgcca aggttgcaat
     9901 ttcgatagcc gtacgcacat cttttggatc aacaggctta tcagtgaaat gcttggtcgc
     9961 atgacgtttt ttatttaatt caagaaattt cataatcgat ttccttttct aattctactg
    10021 cttccattct accataattt gaaagagctt gcagggattt ttcatgatta agtttttcta
    10081 tcacagacat aaaagatata tattggttta tcaggaacat ttctgataaa ctagcaagta
    10141 ctttacattt gaatggagac agtatgaaaa aatttagcct attactagct atcctaccat
    10201 ttttggttgc ctgtgggaat caagctacac ccaaagagac tagcgctcaa aagacaatcg
    10261 tccttgctac agctggcgac gtgccaccat ttgactacga agacaagggc aatctgacag
    10321 gcttcgatat cgaagtttta aaggcagtag atgaaaaact cagcgactac gagattcaat
    10381 tccaaagaac tgcttgggag agcatcttcc caggacttga ttctggtcac tatcaggctg
    10441 cggccaataa cttgagttac acaaaagagc gtgctgaaaa atacctttac tcgcttccaa
    10501 tttccaacaa taccctcgtc cttgtcagca acaagaaaaa tcctttgact tctcttgacc
    10561 agatcgctgg taaaacaaca caagaggata ccggaacttc taacgctcaa ttcatcaata
    10621 actggaatca gaaacacact gataatcccg ctacaattaa tttttctggt gaggatattg
    10681 gtaaacgaat cctagacctt gctaacggag agtttgattt cctagttttt gacaaggtat
    10741 ccgttcaaaa gattatcaag gaccgtggtt tagacctctc agtcgttgat ttaccttctg
    10801 cagatagccc cagcaattat atcattttct caagcgacca aaaagagttt aaagagcaat
    10861 ttgataaagc gctcaaagaa ctctatcaag acggaaccct tgaaaaactc agcaatacct
    10921 atctaggtgg ttcttacctc ccagatcaat ctcagttaca ataacactct tcgaaaatct
    10981 cttcaaacca cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct
    11041 agcttcctag tttgctcttt gattttcatt gagtataaga tatactaaaa gcgattggac
    11101 cagccaatcg cttttttagt ttgcattggc tattttagga aactcttaca aaaaatcaaa
    11161 aaaattcttc acatcctcta catacccatg cttttctatt aagctggcta ataattccag
    11221 attgtgcccc tgatagttat cgtcacgacg cagttcttca tacatttcga taaagggaag
    11281 ccccttggac ttggccaatt ctaactcagc ttcgtaatca taagcaactt tacgaaattg
    11341 gatattgagt aattccccat cttcaacttc tatcacggca tactgggcac ggtgattttt
    11401 taacgcctcc caattaaaat agggcatgcc aatcgaccct ggattgatga tttgttgccc
    11461 ttgacttcca taacgaagca actgcttgtg aacatgacca tagacggcca cgtccgtttc
    11521 cgcatctagc agttggtcaa atttctctgt atcattctca actagcaagt caccaccata
    11581 gttcttattt ggcaaattat gagagataga aaagcgtagc ccgtcaactt ctttcttttc
    11641 cagcaaaggc aagcttcgta gccagacaat cgtttcagga tccattcgct ccatcaaaaa
    11701 ctgggtcatt cgcatgagct ggatttcttg cggatgttcc aaaccatatt cgccatccaa
    11761 ggcctcaagg acacgatcat cccaattgcc tcgaacactt gctgtgatag gaaggtcctt
    11821 tagcagggcg accaagtcat ttgcacctgg accgggaaga aaaatatctc ccagaagcca
    11881 gtattcactg accccttgat ctttagcatc tgcaatcact gcttctagcg ccgtcgcatt
    11941 gccatgaata tctgataaaa ttgcgatttt atggttcatt gtggtttcct tccgtttggt
    12001 aatctactct ttcttctgct acttgaggca aggcttctcc ctgagggttc aactttctct
    12061 gaacagcttc tgctactgct ctaggcacac caacttcgac aatttcatcc acactggctt
    12121 ccttgatttt agttagagac ttgaaatgct tcatgagatt ctgcttgcgt ttaggtccca
    12181 gaccgtcaat tccatccagt tgtgatgaaa aagaattttt ggagcgcagt tggcggtgaa
    12241 aggtgatggc aaagcggtgg acctcatctt ggatgcgttg gaggaggaaa aattcctgag
    12301 aattgcgtga caactccact acctcaagcg gatctccaaa gagcaattca tgggtttggt
    12361 gcttgtcatt cttttgcaga cctgcaatgg ggatatccaa gcccagttcc tcttggatga
    12421 cttgcttagc gatattgact tgaccttgtc ccccatcaat cacaatcaaa tctgggggag
    12481 tcaaaccgtc tcgttgaact ctaccataac gtctgcgaat gacctctcgc atactggcgt
    12541 agtcatctgg acctacaacc gtttttatct tgtacttacg gtaatccttc ttactcggtt
    12601 taccattgac aaagaccacc atggctgaaa cagggctagt tcccatgatg ttggagttgt
    12661 caaaagactc aatgcgaact ggagttggaa tttgtagaag tcgtcctagg ttttcaatag
    12721 ccccttgggt cttttcgact gatttttcta gcaggttaaa tttctgctcc agactaacac
    12781 gggcattttt gatggctaga ttgaccagct gttttttctc tccacgctgg ggtttgagaa
    12841 tcttagtatc caccaaggcc tgaacggctt cttgatcaat atcctgcgga atcagtacct
    12901 cattgggaac taggtgagat ttttcttgat agaattgtcc cacataggtc aagaaatcct
    12961 catctggatc attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttgccctgac
    13021 ggacaaagaa aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc
    13081 gattttggag atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa
    13141 tcaggtcacg gtattccgcc gcacgttcaa actccatagt ctgggctgcc gctgccattt
    13201 tgccctttag ctcatcaatg attttgttat cctgcccttt cagaaaatca gaaacctcct
    13261 gggccataga cttgaaataa acctcatcct tcttacagat ggtgtgggcc atacattggc
    13321 caatatggta gtaaaaacag accttagagg gcgagttggt acattttcga aaagggaaaa
    13381 tcctatctag aagtcgcttg atttcattgg ctgcccccac atctggataa gggccaaaat
    13441 aaagaccacc gtcctttttg acctgacgag taatgataag ccttggatag cgctcattgg
    13501 tgattttgat gaaaggatag gacttgtcat ccttgagcat gatattgtac ttgggcttgt
    13561 tttccttgat caggttgatt tctaggagaa gtgcctcaat attagactcc gtaacaataa
    13621 attcaaaatc cacaatttca gacaccagag cctctgtctt ggtatcatga cttccacgaa
    13681 aataggaccg tactcgatta cgcagatttt tagcctttcc tacatagata atggtgccat
    13741 ttttatcctt atgaatgtag caaccagggc tggtcggcaa gagctctagt tttgatttaa
    13801 tcaagttgtt catagttcca ttatagcaaa aaaagtaggg aaagatagta ccctactcac
    13861 tagtctcata tatttttcag aggtttgcaa catcctcttc ctggatacca taaaaggaac
    13921 ctgctggttg catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact
    13981 catgttctgc cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat
    14041 aataatgatt caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac
    14101 tttccgcctc tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg
    14161 ccttactaga ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga
    14221 ttgcttctaa ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag
    14281 cagaggcctg tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag
    14341 gcagttgccc tgttttctcc cattggtcaa tactttgttg accaattttt actgaccgtt
    14401 ctgcttgctt tagcgctcct tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa
    14461 gcacacataa gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaaaaaa
    14521 agaaagcccc tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag
    14581 aattatttta ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc
    14641 ctactatttt tttgagtaac tggatagctt tgtattttaa aggcgatgga tggtaacgga
    14701 aagtacccgc tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat
    14761 cacttccatc aaaaatccct tgaatgccta ggaaattgta tttaggtatt ccacgtttta
    14821 tgctttccaa cataacatat ttttgaagca gtgcaggggc atagaactta ttaaactcag
    14881 tgtaggaacc actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag
    14941 ctaaaacaat atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa
    15001 cttcaaacgt ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat
    15061 gaggattttt actcaaatca agtcgcaact tgtccaagtt ttcttctagt ttactttgtt
    15121 caccttgcaa tttgctcata tagtccgaaa aatttaagct tgctatgaga aactccgctt
    15181 gttctccaaa agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc
    15241 tacgttcaga ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact
    15301 ttttcaaccg aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa
    15361 aacttttaag caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg
    15421 gttctccacc tgggtaacct attgttaagc catcaaattg ataacctaaa tcagtcaaac
    15481 cttgaataat actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat
    15541 aagtttcata aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta
    15601 actctgcata aaaaactgga agagcatctt gttgggtata aatcggcccc gaattgagtt
    15661 ccatatgcag accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc
    15721 cttcttgttt caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca
    15781 tctggacaga ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt
    15841 ctttcgtgag tgttgttagt gccatatact tactttctat gtttttttct taatgtttta
    15901 cggaaatcaa gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca
    15961 cccaagtatt cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg
    16021 agagagtttt caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga
    16081 gccgtttcat accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca
    16141 gcatatatat tgacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact
    16201 ctcgcttgac ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct
    16261 ttttccttct tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa ggtctcttcc
    16321 aaggctctat ttttcgctaa ctgttcttct aactcttgcg aacgtttaga aacatccaag
    16381 gtggccaagg tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct
    16441 tcattcctca aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa
    16501 tctaatagtt ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata
    16561 gcctgttttg ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc
    16621 tgaatacgag gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc
    16681 atttgttgca aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg
    16741 attaaacttt gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg
    16801 cgagcatagg acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc
    16861 aatataggtc ctcttgggat ataaaacatt ttatagccta gcggaagagt tctaatcaaa
    16921 atactagctg tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa
    16981 ttagacttaa cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg
    17041 acaaactgat catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct
    17101 ctttcctcca gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca
    17161 tattttattt tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct
    17221 aatttgaaat caattggtag agttgttaaa aaaacttcca attgtttttc ccagtagtac
    17281 cactcgtgag ttccagcgct atggctatag gtcacatcaa aacctagttt tttgagattt
    17341 ttcactgcga gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt
    17401 ttggtctttt tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag
    17461 tctctaatct ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca
    17521 ggagaaaagt tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt
    17581 gtcgcaagag ccagtttgaa acagccgtag cctcccatag aaagaccagc tataaaggtc
    17641 ttttcacgct tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct
    17701 gctagagccg tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta
    17761 ttgggcataa caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta
    17821 agccaactat tatgatttcc agacatcccg tgcaaaaggt acaagacggg aatatcttca
    17881 cactctggtt cttccactcg attggcatca gggtagagga cattcatccc ccactccata
    17941 tccaatactt gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt
    18001 tctataagaa aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt
    18061 ccatgactac tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca
    18121 aattatctcg aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagataat
    18181 cttctaccgt ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga
    18241 gataaacaaa tccacgcgtg tgaacacgag ctctagccac aattttcttc tcacgacggt
    18301 tgactgtaat agccacgatg aaaattccat cctctgacaa gaccttacgg tcacgaagaa
    18361 caacatttcc aacatcacca atggcattcc catcaattaa gatatctcct gctgaaaccg
    18421 atccagctgg aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga
    18481 agatgcgttc tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac
    18541 gatactcccc ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca
    18601 aatcacgcac atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc
    18661 cacctgcctg ataaatcata ttttctacac gcgcaacaaa ggcttcttta gcaatagacg
    18721 gagccgtagc aatatagacc aggtccccat ccttgatttc tacataacga tggcgaccaa
    18781 tcgacatctt acgaagtcca ttgataggtt cacccatacg acctgtctca agaataatca
    18841 actcatggtc ttcaaagcga gacatatctt taggcttaat caagagaatt tcgttggcta
    18901 aagacaactt cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca
    18961 agacgatacg tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat
    19021 tactggaaac agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt
    19081 catccctaac ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac
    19141 tgaggagagc caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat
    19201 aagattcact agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg
    19261 atgtcttcaa gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa
    19321 ccactgtccc accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt
    19381 tcttaacggc atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc
    19441 caaatacagg aactttagcc tctgccaaga gataaggtag agcaccaatc gcatccgcat
    19501 gcccgtgggt caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt
    19561 ttggaatcac cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca
    19621 aaacaaaaat ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac
    19681 caccaagtgt tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga
    19741 ttatagggca actctaccct cttattctaa aagttctaat actttcagcc gaatcttttc
    19801 ctaccattat accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt
    19861 tgatttccca actctttcct aacttctact ctttttccat caaaaaatca taaatttctt
    19921 gcaccgtacc cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa
    19981 tttgactttc tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt
    20041 ttatcgtcac aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt
    20101 gaatattaag atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact
    20161 ggtaaatagt cttgtacaat ttggcaaact gatctctagt cccataacct gtcagataat
    20221 aggccttgtc aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg
    20281 tcttcagctg agtaatatcc tctggaatgt tttttacgac aatagcttca ctagccgcaa
    20341 gatttggcag ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt
    20401 ttccacgaat gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga
    20461 gggcagtttg gccattccat tggttgacag acaatttaac cgctaactct agattcttgg
    20521 tttgagaaaa ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct
    20581 cacccttgga aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt
    20641 cgacctgaaa attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta
    20701 aacgttcaaa acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta
    20761 ggtttaactt attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa
    20821 cctgagataa atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac
    20881 ctccaaaggc gataaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt
    20941 ccacactacg agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct
    21001 gtcccaattc ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt
    21061 ccttggccaa gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga
    21121 tagactgaac gatttccttg cgctcttcgt ttttctggtg aatcataaag gcaatctcat
    21181 gcgcttcctc atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc
    21241 gacccaaggc attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt
    21301 tggcagcaat cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca
    21361 acatttccag accatattga actaagatac gattttcatc cgtcagactc accatatctg
    21421 caatagttcc aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac
    21481 aagccaactt gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg
    21541 gatgttcagg atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt
    21601 ctgtcacaat gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa
    21661 ccccattgtc caccgtcaca atcaaggaaa ttccttcttg ctcgataaag tatttataaa
    21721 cactagcatt agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag
    21781 caccaagttg ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat
    21841 agtctccata aacgagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg
    21901 ccttgtccat atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa
    21961 acttcttcag actttcttgg tcctgaatcc ctctctcaaa caataaccga gccacctcag
    22021 gacccagtcc agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa
    22081 actgccattc ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg
    22141 cttcattata acatgattta gacgttttct ctatccagat tgctttttta taacatttta
    22201 tagtatattg aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt
    22261 gactgtcccg atcgatttgt cctgttctta tttcactata gtgaattttt tcagatatgg
    22321 tttgacaaga acattctttt attgtagaat cgtgttataa aatctaacac aaaggagatc
    22381 tctcatggct ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcact
    22441 ccgcaacatc aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg
    22501 ctctgggaag tccactctta tccgtacgat caatggttta gagactgttg acaaaggaag
    22561 tctcctagtc aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg
    22621 caaggaagtc ggcatggttt ttcaacattt taacatttat ccacacaaaa ctgtgttaga
    22681 aaacgtaaca cttgcaccca ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac
    22741 cgcccaaaaa tatctggaat ttgtaaatat gtgggacaag aaagattcct atcccgccat
    22801 gctatctggt ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga
    22861 actcctcctc tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct
    22921 agcagttatg cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat
    22981 gggctttgct cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt
    23041 agatacgaca gatgtcgata acttttttga caatccaagc aaacctcgtg cccaacaatt
    23101 cctcagcaaa attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa
    23161 aaaaattctt tttatcagca ttattgatta gccttttcgg ccttgctgct gccaaaccag
    23221 tccaggctga tactagtatc gcagacattc aaaaaagagg cgaactggtt gtcggtgtca
    23281 aacaagacgt tcccaatttt ggttacaaag atcccaagac cggtacttat tctggtatcg
    23341 aaaccgactt ggccaagatg gtagctgatg aactcaaggt caagattcgc tatgtgccgg
    23401 ttacagcaca aacccgcggc ccccttctag acaatgaaca ggtcgatatg gatatcgcga
    23461 cctttaccat cacggacgaa cgcaaaaaac tctacaactt taccagtccc tactacacag
    23521 acgcttctgg atttttggtc aataaatctg ccaaaatcaa aaagattgag gacctaaacg
    23581 gcaaaaccat cggagtcgcc caaggttcta tcacccaacg cctgattact gaactgggta
    23641 aaaagaaagg tctgaagttt aaattcgtcg aacttggttc ctacccagaa ttgattactt
    23701 ccctgcacgc tcatcgtatc gatgcctttt ccgttgacca ctctattcta tctggctaca
    23761 ctagtaaacg gacagcacta ctagatgata gtttcaagcc atctgactac agtattgtta
    23821 ccaagaaatc aaatacagag ctcaacgact atcttgataa cttggttact aaatggagca
    23881 aggatggtag tttgcagaaa ctttatgacc gttacaagct caaaccatct agtcataccg
    23941 cagattaagg aggataccct atgacagatt tatcatcttg gacagcctat tttcaggatt
    24001 ttggacaatt tttcaatggt ttcctcttta ctcttgccct agcgattgga tcctttatcc
    24061 tcgccatggt cttaggaatc ttctttggtg ccatgtcaac cagtaaacgt ccaattttac
    24121 gcattttagc tcgcatcttc gtggaatttt accaaaacac tcccctcttg gtgcagtttg
    24181 ttattgtttt ttatggccta cctcttatca gtgaccacat catcatgatt ccaatttatt
    24241 ggacagccgt tctctgcgtg ggactctatc acggcgctta tatcgctgag gttattcgtt
    24301 cagggattca gtctattcct agtggtcaga tggaggccgc cttgtcgcaa ggttttacct
    24361 atatcagtgc catgcgcttg attatcttgc ctcaggcctt ccgcatcatt ctccctccat
    24421 tgaccaacca aattgttaac ctcatcaaga acacatctac tgtagctatc atctctggag
    24481 tagacttgat gtttgtgact aagtcttggt cggctctcaa cggaaactat atcccagcct
    24541 ttttaggtgc tgctcttctc tactttgccc tatgcttccc tgttgcccag tttggtcgca
    24601 agatggagca agccaataaa aaagcctatt cactttagga ggttactatg gaatctattt
    24661 tagaaatttt aaccccagat aacctagtct ttatctttaa aggatttggc ttgaccctct
    24721 atatttctct gattgccatc atcctctcta ctatcatcgg taccgtgctt gccgtcatgc
    24781 gaaatggaaa aaatcctatc ttacgcatta tttccagtat ttatatcgag tttgtgcgca
    24841 acgttcccaa ccttctctgg atttttacta tctttttggt gttcaaaatg aaatccacac
    24901 cagcaggtat tacagccttt actctcttta catcagcagc cttggctgag attattcgag
    24961 gcggtctcaa tgccgtagac aagggacaat acgaagcagg aatgtcacaa ggcttcacct
    25021 cagcccaaat cctctactac atcattctcc cacaagccat ccgcaaaatg ctaccagcca
    25081 tcatttctca gtttgttacc gtgattaagg ataccagtct cctctactct gttatcgccc
    25141 tacaagaact ctttggagcc agccaaattc tcatgggccg ttatttcgaa ccagagcagg
    25201 tcttcagtct ttacatcctg attgccctca tctacttcag ctttaaccta gcgatttcta
    25261 gcctgtctca tatgctagcc aaacgttggc aacaagctgc agaataatac tcttcgaaaa
    25321 tctcttcaaa ccacgtcagc ttcaccttgc cgtactcaag tacagcctgc ggctagcttc
    25381 ctagtttgct ctttgatttt cattgagtat aaacagccac tctccagttc aattggagag
    25441 ttttttgatg agagtagata tttatagacc tcaatttgac accatacatt ttctatgata
    25501 aaatgtaaca aattcattta caacaaatcg aaatctaaat gaaatggaat tttctatgaa
    25561 atcagtcaaa ggactactct ttatcatagc tagttttatc ttgactcttt tgacttggat
    25621 gaacacttct ccccaattca tgattccagg actagcttta acaagcctat ctctgacttt
    25681 tatcctagcc actcgtctcc cactactaga aagctggttt cacggtttgg agaaggtcta
    25741 caccgtccac aaattcacag cctttctttc aatcatccta ctaatctttc ataactttag
    25801 tatgggcggt ttgtggggct ctcgcttagc tgctcagttt ggcaatcttg ccatctatat
    25861 ctttgccagc atcatccttg tcgcctattt aggcaaatac atccaatacg aagcttggcg
    25921 atggattcac cgcctggttt acctagccta tattttagga ctctttcaca tctacatgat
    25981 aatgggcaat cgtctcctta catttaatct tctaagtttt cttgttggta gctatgccct
    26041 tttaggctta ctagctggtt tttatatcat ttttctatat caaaagattt ccttccccta
    26101 tctagggaaa attacccatc tcaaacgctt aaatcacgat actagagaaa ttcaaatcca
    26161 tcttagcaga cctttcaact atcaatcagg acaatttgcc tttctaaaga ttttccaaga
    26221 aggctttgaa agtgctccgc atcccttttc tatctcagga ggtcatggtc aaactcttta
    26281 ctttactgtt aaaaattcag gcgaccatac caagaatatc tatgataatc ttcaagccgg
    26341 cagcaaagta accctagaca gagcttacgg acacatgatc atagaagaag gacgagaaaa
    26401 tcaggtttgg attgctggag gtattgggat cacccccttc atctcttaca tccgtgaaca
    26461 tcctatttta gataaacagg ttcacttcta ctatagcttc cgtggagatg aaaatgcagt
    26521 ctacctagat ttactccgta actatgctca gaaaaatcct aattttgaac tccatctaat
    26581 cgacagtacg aaagacggct atcttaattt tgaacaaaaa aaagtgcccg aacatgcaac
    26641 cgtctatatg tgtggtccta tttctatgat gaaggcactt gccaaacaga ttaagaaaca
    26701 aaatccaaaa acagagctta tttacgaagg attcaagttc aaataagtaa tcatactctc
    26761 ctgggatttc ccaggagagt tttttatagc caaatgaaat aagacctgaa cgatggaatt
    26821 ttggcattca aatcaattga taagaatatt ttatagtgga gtgaaatagg atacgaacaa
    26881 attgattagg aaaatcaaat gaatttatag aaatctttta gcagttatgt tgtcctattc
    26941 tagtttcaaa acgctataga agcagcattg tgctagtcta gattcagttt actatactaa
    27001 aacgagtagc ttgaaatcaa aaaacccacc ctcacaggca ggttttatct gtattattca
    27061 gctagattat gctttacctt ctgaaccgaa tacgtcgata cgttcttcaa ctgatgcttg
    27121 gatagctttt acaccgtcag ccaagaattt acgtgggtcg aagagttttt tcttgtcgta
    27181 ttctgcttcg tttgcttcgt agtcacgagc aaatttacga gttgcgttag cgaatgcgat
    27241 ttggcattct gtgttaacgt taactttggc aacaccaagt ttgatagctg cttggatttg
    27301 ctcatcagga atacctgatc caccgtgcaa tacgattggg aatcctggaa gagcttctgt
    27361 caatttttgc aagtggtcaa ggtcaagacc ttcccagttt actgggtaag gaccgtggat
    27421 gttaccgata ccagctgcca agaagtcgat accagtttca accattgctt tagcgtcttc
    27481 gattggagcc aattcacctt taccgatgat tccgtcttct tcaccaccga tagtaccaac
    27541 ttcagcttct actgagatac ctttagcgtg tgctttttca acaacttctt tagccaattt
    27601 aagattttct tcaactggaa ggtgtgaacc gtcaaacatg attgaagtat aaccaacttc
    27661 gatacactca agtgcatctt cgtagtgacc gtggtcaagg tggatagcta ctggtacagt
    27721 gatacccatt gattcaacaa ggttagcgat caagttgcga gcaactttgt aaccacccat
    27781 gtatttagca gcacccattg aagtttggat caaaactgga gcttttttag cttctgctgc
    27841 gcgcaagata gcttgagtcc actcaaggtt gtttgtgtta aatccaccaa ctgcataacc
    27901 gttgtcacgg gctgcttgga caaatttttc tgctgaaacg attgccattt tatcaggcct
    27961 cctgtatatt tttatgggtc atcccattta cattgttcat tttatcactt tttgccaaaa
    28021 aaatctagtt tttcccgcag tttcaattga ttttcttcta actccaccta tgtaaaccct
    28081 ttctctccct agtcttggac gacttttgga aaatctataa agaaggttaa acgattctcc
    28141 tccatctcga aacgataagc taatttttca tgttctaata gactcttaac cacaaagagc
    28201 cccataccag accccttgac cttgcgacta gcattgtcag aaaaagactg ggctagtttt
    28261 tcttgttcct ctgagctaca gctattttcg ataaaaagtt ctccttctct ttctccaatt
    28321 cgaactaagc cacctggaac agagtgctta atggcattgc tgatgagatt agaaagaatc
    28381 aacttcataa ctgatgggtt tagataagcc tgctgatggg tcaaactatt gtctatctgg
    28441 agctctcttt ccttggctag caaggcataa tatttgacca gattttgcgt catctggagg
    28501 aggtcaattg tttccctatc atctcgcaat tcctgcacag aagagaggga aagtatctgc
    28561 agaacatggt gattgagttc atccacaatc cccaaggcaa ctcccagata ctggtctcta
    28621 tccttataac gaccgatatt ctctctcata ttttcgatta ggattttcaa actagccagc
    28681 ggtgttttca attcatgaga agctcctcgt aggaattcga ccttcatctt ctccagctgg
    28741 agaatggctt cattcttttc atgcaagtcc gcaataacag tcaagagatg ctggtagagg
    28801 ctattgattt gttccttgag attacctatc tcatccttag aatccacgcg caatcgcact
    28861 tgggaatcca ggtccatcat ccgacgggtc acccgcttga tttccaaaat cggtgcaaca
    28921 atagtccgag cgtagatgta ggccaccaag agggaaatca gaaaggaggc cagcaaggta
    28981 tagggaagaa actggagact gatttgctcc gcttcctttt gtaaatccat ggaagctaga
    29041 aactggagaa tcatagtacc accgtcttgc gttttcacct cgcgctcctc aataaagaga
    29101 gaggttgtct ggcggtctgt gtccagagga agactgtcct tgacttctaa cttgtcctcg
    29161 gtcatctcac ctttgacggt ccccttgata tcactagtct gggaatacaa gtctaacact
    29221 tgctcgatac tctgcctatc tttcccttct agggactggg caatggctgt tgccttttga
    29281 ccaatagttt cctgacgatg actcagataa gtcgaaggaa aaagaaaata aatagctaaa
    29341 tgaaggcaga taaccagaac actaaatatc gagaaggtat agataaatat ctttgcaaat
    29401 aaacctgttc gtttcatttt cgctccaatt tataaccaac attgcgcaca gtgaggatac
    29461 aatccaagtc tagctttttc cgcaattcct tgatataaac atcaataaca cggtcaaagg
    29521 gaacctcatc tgtcgctttc cagacggaat cgataatctg agaccgagtc aaggcccggc
    29581 cttcattttt cactagatag tccagaattt ccaactcttt ggcattgata ggcacttctt
    29641 gacctgcgag gcttgcactg tagctttcaa agtccacctt ggtatccttg taagaaaaga
    29701 ttcgtcctgt atcgtagtag cgcttgaaaa tcgcgtccac cctcactttt aagagggaga
    29761 gggagaaagg tttttccaga tagccatctg ccaaagaggc aaaggcactc atcttgtatt
    29821 cctcatcctg aaaagctgtc aacatcaaga caggaacctg actggtttta cgaatctcag
    29881 ctagaacttc taagccgtta agcttaggca tctggatatc cagtaaaacc agggccacct
    29941 catagctaga aaattgctcc agagcttcct gaccgtccgc tgcctcaata gtttcatagc
    30001 cacaatccgt caaataatca ctgaccccct cacggatcat ctcttcatct tctacaatta
    30061 aaattttcat actttaactg ctctctattt tttatttttc ttagaataaa tacctactct
    30121 attttctatt atagtctctt gctggccttt tgtctgtaag taactgatca ctagataaaa
    30181 cgttgtgaaa ttcctttctc ataaattcca tagctttagt atattatatt taagcaataa
    30241 agtacaaaga aaacaactga aagcaatgat tttcaccact gctttcggat ttattttgaa
    30301 ttgttaaata gccattccta tccactattc ttgaatagaa acacaagatg caatctttat
    30361 tccagactca ttttttcaaa tttattcacc atccagcaag agctcttttg gttgttttct
    30421 aaggagattg cttgaagcaa gcgccataac gagaaccact agaaccaagg caaggacaaa
    30481 aatgatgata aagtctgatg tctgaataga aatgtctagg ctcgacaagg tcttgctaaa
    30541 gccatctact tctgcaccac caccaaggtt agaggcttga gccgccttac tagcctgttt
    30601 ggcaacacct gaagtcacat tggcaaggac agtgtttcca attgcacggg cagtgtaatt
    30661 agctaggaag taagcagaaa ctagagcagg gatagcaatc aagatagatt cggtgatgaa
    30721 ttgacccaag atacttgcct gcttgaggcc gatagagagg agaattccca cttccttgcg
    30781 acgggcgttg atccaaaggc tgagcaagag ggcaaggagg agaactgaga agctcaagct
    30841 accccagaag aggaggttgg ccatcttgta cataccagag atagattgct caagagctgg
    30901 gtagttagag gagctcttga cgagtgtgta gctcttccag ttgataccac tgatgccatt
    30961 caactctttc ataacatcat ccaagttctt gtctgctgtt acaaagaagg ttgcgtcccc
    31021 ataaatggct gtgtcttctg tgtatccata aagttttgca gcagtgtgaa tgtctgtaat
    31081 agctgtgttt tcgtaaagtt cttgtgagta ggttactgct gacttattat gaccatcaaa
    31141 gagtcccttg attgtcactt caactgtttc cttggctcct ttttcattat ctgcatcgta
    31201 gatattagag tccagtttaa ccttgtcccc tactttccag ccgtgtttgg ctgccaagtc
    31261 cttgtgcaag aggattttat ccttgtcgtc gttggttaag tgctctcctt cgactagttt
    31321 ataagaacca gagacaaact tgtcttcttt agaggagtca ttgacacctg taatcatcaa
    31381 gctacttcca aaacgtttgg cacgatcagc agtgagattc ttcttggttt ctggcgtttc
    31441 aatcaggtca tatccagtca aatctccgat agcgttgata cgtttgacat aagactcaat
    31501 ggccttgttt tcggtgattt ttttgatgtc ttcacccttg atattcccag caccgcgagg
    31561 cgttccttgg ttgacgcgac gattgatttg catggagaag ctattggtga tatttttaaa
    31621 ggtctcctga gaagccttgg cagtagctcc cttgattgac aagccgacca aactcaagct
    31681 cgccatgagg agaataatca ggaagatgac aatcgatttg aaaaacttcc ttgtaacata
    31741 ggcaaatgcg ttgtgtaaca tagattccct ttctagattt tgttttaatc attctattaa
    31801 agtaagctca aattatttac tagtattgcg cgtttcagtc agtttcttat cctttaattc
    31861 aagtgtaata tctgacgctt gtgccacttc tttactgtga gttacgacaa tcacacattt
    31921 acctgttttc tgggcaagtg atttgagtag ttcgacaata tctccagcag ttttaggatc
    31981 cagatttcct gttggctcat cagctagaat aactggagct tctgagacca aactgcgagc
    32041 aatggcaaca cgttgctgtt gaccacctga taactggaga acattccgct tgatctggct
    32101 ttcatccaaa ccaagctcaa gaagtgtatt cttgcttgcc tttttgttga ccaatcggat
    32161 attttccagc ggagaaagat aatctatcaa gttataattt tgaaagacca gggaaatatg
    32221 gtgcatgcga tggtaagaat agcccttctt acgaatatcc tctccttgaa aaaggataga
    32281 accttcaaca ggactatcta gaccagcaag tagggacaag agtgtggatt ttcctgctcc
    32341 tgactcccca ataatactgt aaaattttcc gggttcaaaa ttataattga tctgatatag
    32401 gactgcttca gcagtattct tataacggta ggtaacatct tgtaattgta ataaagtcat
    32461 gatttctcct tcttaactaa tagatgataa aatttctttc ggtgattttc taaataagaa
    32521 taggaaacaa agggctacag ataagcaact aagcagaact agaaaaacat aggattctgc
    32581 aaaagataag atgctagttg ataaactgct tgctttggct agtgtatctt gtaagcttgc
    32641 ctgatctcca cttgctagta gagtttggag taggtaagtt gtgattccgt ttcctgcaac
    32701 aaatgctgga agcaaagctc caagagatac caaaactacc tctaaacaga attgtaggaa
    32761 aatcgagctc ttgccttttc caagtgcaag taaaatcccc acttcataga cccgttctct
    32821 caaccagaga gacaaaacca gaattaaggc tccagatcct gctatcaaca tcccataaag
    32881 gaagatggtc aggaaggttt ggaaagttgc aactgagtct ttgatttgtt caaaagcctt
    32941 gttttccttt tcgacttggt agccttgatt ttccaaggcc aagttttcta cctgcttcat
    33001 gagtccgtcc atttccttag gattttctac atagaagcgt gctgcactga cttgagcttc
    33061 actattgccc aaaagggttt ggctactttc atagtctgta aagacttgat tttcactgaa
    33121 gtcagaagac aagcctgtga atttctcttg ttttttacca gaaaagatgc cgataatctc
    33181 aaactctact gtttgtcctt ttccagattc agactgacca gcatccaagc caatcttgtc
    33241 atgaagcgaa agaccgttct tcttagccaa ttcttcgtgg ataaggattt tcttggaatc
    33301 ccctttttga aggtgtcgcc cttcttttag attgaaagcc gaactggtaa aggttacatc
    33361 cttggatgaa tcctcaagag ccgttaagct aaccaagtta ttgtctgcag ctgataaatc
    33421 atcacgctcc acgctctgct cgccagtcac tgcttccttg tcttttagtt ttgcgaccgt
    33481 ctcaagttca ggagagacat tttccagccc cttaatcttg cttacagatg ctaggtctga
    33541 caacttgaat gtctgaccat tctctatctt cttaatagaa aaagatgtat tgagtgattt
    33601 ataaagattg ctttctactg ttttgttgga cttcatcaga gtcaaacagg ctgaaattcc
    33661 ggccaataag accaataaaa tcagaaataa aataaaactt ctcagtcgct ttctgctgac
    33721 ataagcccaa gctctttgga ttggattcat ttgtcacctc catatttgta agactattat
    33781 aaaacccaaa tatgaaatgt ttatgaaata cgaaaaaaaa atatcgagta ggggataatc
    33841 tctagcccct ctcacaccac cgtacgtgcc gttcggcata cagcggttca actaactttt
    33901 aacgcatgtc gttcaaggta ataatccaaa cacgaaacct gttcacgttt ttcaaggact
    33961 ggttttgata tagcacgttt aagtaccgac ttctgagcta ctatagtaga ttgaaactag
    34021 aatagtacat ctcttcttct aaaacattgt tagaaatcga tttggctgcc ctgatcgatt
    34081 cgtcctactc ttatttcatt ttactataat tgatagtggt cgctccagcc agatacctta
    34141 tctgctatcc atttaggaac ccctaactta agcaatcccc ataatcgtct cgatttcttc
    34201 ttccattgct tccagataat cactcgtagg cgagtacgca agcgctcatc tatgctagtg
    34261 actatacttt tcatatttat aattcattcc tttcgtttca ctcaaggcac aacacagaat
    34321 gaaaaagtgt tgtgctcttt attttgtttt ataataatag tgagaaagcc tatcactact
    34381 acaaatcacg gggaggtgaa taagtgagtg gtacagccac tacctcgcat attttgtcac
    34441 atcatttaac ggtacataat aagttgtacc atctgaataa gttgctacaa tatcatttgc
    34501 atgctctcct tcacctttag caaaggttgg agctcctgct ggataatttt tatttgcctc
    34561 tttcaatttt tcaataatgg catttttttc tgtatctttt atattatcag gatttttcac
    34621 taagattttg tctggatatg tcggtttagc agaaacaatt tttactgtta tttctttttt
    34681 attcgaagca cttgtccagt ttccagcatt atctttagca tttaatttta cagtaattcc
    34741 tgaactagga acttcagtag caggttgatt atcaacatta ttcaacttta atttcaaaag
    34801 agctgttgca tcagacgttt tatcaatcgt tgtatataat gatgaattgt tattataacc
    34861 agtttcttca tatttagctg tttgtgagct acttgaaaca gaactgaaat tatgcccact
    34921 acctccctga ttatcttcaa tgcttacgtc taaatgaact tccccactat tatttggctt
    34981 agcaacaact gttatagtaa aataacataa aatttgcata aatagattag ggaaatcaaa
    35041 gcagcttcta ggaatgtttt agcagtcaca gtgtactttc ccagcatcaa gccactataa
    35101 ctctgcacat aaaaatggag aagatggcaa tcctcttctc caaatattaa cttctttaca
    35161 aaccaactat agttgacaaa gaacctaaaa tcaattgata acacaaggtc aggtcggtca
    35221 actctttcaa ctgaagccct gtcaactctt cccatttatc aatcttgtat tggagagaat
    35281 tgcggtgcag atagagttgc tgggctgttt tagtgagaac agcactattt tcccaaagag
    35341 agagaatgat ttcctgaatc tgatcttgat ccaaaatcat ctggtgtaga cattctttaa
    35401 ttggcttcaa gtccacgagt ctttctccca tactccaaag atagagctga gaaaaagtat
    35461 gaacaccttg gtgaccctga cgccaccatg tcttgaacaa atcccgctca gctttgatta
    35521 agtctgatag ggcttgatgt cctgtctgag accaaacctg acccaacatg atagaaagac
    35581 gaagtccaaa gtcatactca accgcttcaa tcgtatcact taaaatatct cttacagaag
    35641 tgtatttgtc ttgttgaagc acgaaaacat aatcctgagc tccgacctgt agcactgtct
    35701 gacaattcgg aaaaagagtc cgcatcatat ctagccaaga agccagattt tcctgctgaa
    35761 aataagaaag atggcaataa accaactgaa tctttttaaa aacttgcggt gcctgtccct
    35821 tgccttcaac cagataggaa taccaagggt ttagcgaacg agcctgctcc tgctgggtca
    35881 aaagggcaac caactgcttt tcacgctcgc tgagcccagc ttcctccagc aaaatccact
    35941 gctgagaagc taaagggagc gtgagatagc cctctttctc tactggttgg tctgaaatcc
    36001 gagcctcagg aaaccagtct tgtagttctt tttccctcat gttctagccc tccacttttt
    36061 ggatgcacca tgaaaccaaa ctctcaagac gttccagatt ctcagtcata tggagatagc
    36121 ccataaccgc ttcaaatccc gtggacatac gataagtcac gacatctgca tttttagcct
    36181 ttgtgtggct attggtattg cggccacgtt tgtagatttc ttcttctttt tccgttagga
    36241 cctgctcctc caacatgaga gcaatcaggc gagcctgagc cttggctgac acatacttgg
    36301 ttgcttcttg atggagttta ttgggtttgg tcataccttt gaggatgagg tgacggcgaa
    36361 tatacataga atacaccgca tccccctcaa aggctagcgc aatcccgtta atgagattga
    36421 catcaatcac gtgtccacct cactccatcc ttggtatcaa ggagcttaat tccttgagta
    36481 accaattggt cacggatttg gtctgctgtc gcaaagtcac gattggcacg cgcctcttgg
    36541 cgtttttgaa tcaagtcttc aatctctgca tccaaaactt cctcaacaaa gacaattcca
    36601 aaaatttcta acatatctgc aagagcttgc ttgacacttg catcatagtt ccctgagttg
    36661 atccatttgg ccatttcaaa gacaactgtg ataccgttgg cagcattaaa atcttcatcc
    36721 atagctgcta caaacttatc tttaaagttt tgtaactctt gggcatccac gtttcctgta
    36781 aatggttgtt cgtaagtatt cttcagatac ttgagattgg tctcggcatc gcgaactgcc
    36841 ttttccgtga agttgatagg cttacggtag tgctgggtcg caaagaagaa acgaagtact
    36901 tgcccatcaa gagttttaag ggcatcgtgt accgtaatga agttacccaa ggacttagac
    36961 attttgacat tgtcgatatt gacaaagcca ttgtgcatcc agtagttagc aaaagccttg
    37021 cctgttttag cttcagattg ggcaatttca ttggtgtggt gtggaaactc taggtcagct
    37081 ccaccaccgt ggatatcaat ggtatcacct aaaatctctg tcgacatgac tgaacactca
    37141 atatgccaac ccggacgtcc aggtccccaa ggactatccc aagaaatctc acctggtttg
    37201 gaagatttcc atagagcaaa gtctacagga ttttccttac gagccgtttc ttcatcggta
    37261 cgacctgaag cacctagctc caaatcttcc aaggttttat tagccaattt agcatagttg
    37321 tgggattttt ctacacggaa atagacatcc ccttgactct cataggcaaa gcctttctcg
    37381 atcaagtctt ccacaaaacg gatgatgtct gccataaact ccactacacg cggatggcga
    37441 gtcgcaggtt tcacgcccaa ggccgtcaca tcctcacgaa aggcagcgat gtacttatcc
    37501 gcaacctcct gaggcgtgat gccttcttcc ctggcacggt tgataatctt atcatccaca
    37561 tctgtaaaat tggaaatata ggcaacctta tacccacggt actcaaaata gcgacgaatc
    37621 gtatcaaaag ctaccgtcga acgggcgttt cccacgtgga tatagttgta caccgttggc
    37681 ccacaaacat acatcttgat cttgccgtcc tcaatcggga caaattctcg caaatcacga
    37741 gacatggtgt catagatttt aatcataaat cataatcagg aaagctaaaa tccaagaact
    37801 gttagtttca tcactaaact aagagctcaa gtaaatttca gtccgaatgt ctctacactt
    37861 cggaatccct tgctcctttc tcattcagat aaaccacctg tgtctgtttg acaaagccaa
    37921 ttttttcata caaacgtttg gcacctacat tgctatcttc cactgcaatc tgaaattcct
    37981 tatcattttg ctcaattagt tggttgacaa gggattttgc taagtagctt ccatagcctt
    38041 tcccacgttc aggttctgat attgctaaac cgtagaagta attcgtatcg ctcgataaat
    38101 caaccgtgca agtcccaata acctgaccag cttttaataa aatatatagt cggctttctg
    38161 gatctttcag agcttcagcg acatatctat ccacaacttc tctcgattca tgttcctctg
    38221 aaaatgcctg aaattttaat tgactaattt gatcctgata cgaactatct gctaacaaaa
    38281 tttcaagatg ggaaacattt gctaacggat aaggtcttct atccttacct aaccaagttt
    38341 ctgtctcttc atcctcgatt agtccccagt tactggcaaa gtcaggatga ttctctaaaa
    38401 aaatacgttc tgtctgaaaa gtgactgacc gaatagggaa agaagctgtt tctctctcaa
    38461 aactagtaaa caatgcacgc gcaatcccct gacggcgatg acctggatga accagtatcg
    38521 tcacttctac atcttggtca tctgcataga cagttaataa accaacaagt ttgccttttt
    38581 cataataaag gaaaaaggcg ggcatgtttg ggtcaaaatt aagcatgtta gagagatagg
    38641 gatcgcgata ggtaccgtca tagttttggc aacagttaat tacttttttc gcctcagata
    38701 gctcctcttg gcttaacttg tttcttgctt gaatcatata ggtatcctct acaaaccaga
    38761 cgatctgtga ctggcatctt tagcctgctc gagtttattg acataatact ctcgtttttc
    38821 ttcgacttcg tgaataacag gctcatcttt cttaccatga agacggacaa tcttggccgg
    38881 aataccgaca accgtcacat cactaggtac atctgctacg acaactgctg cagcaccgac
    38941 cttggcattt tcaccaattt ccacaggtcc gataacttgg gcatgggctg atatgagggc
    39001 tccctttcgt acagtcggat ggcgtttgcc acagtctttc cctgttcccc caagagtcac
    39061 tccgtgatag agaagaacgc ctttttcaac aatcgctgtc tctccaatca ccagaccaga
    39121 accatggtca ataaagacac ctgaatcaat ctgggctcct ggatgaatct caatctgagt
    39181 ccaaaagcgc caaaactgac tgtgcatacg agctaagagt ttgaagctgt gcttccagag
    39241 aaaatgcgag agacggtggg ccgccaaggc cttgacacct ggataagtca gcaaaacctc
    39301 caaagtggtg cgggccgctg gatcattttc ttttacgata tcaatggttt cgcgccacca
    39361 ccccatacat ttctcctttt cttattctga atcttttggt gtttctgtaa attctttctt
    39421 aggtttgtga tccttgtgat gacgtgggcg gtgagggcgc tcagactttt cacctttttc
    39481 atcatgctca ggttttggcg gacgaggtag aagagccttc atagaggcat cgatacggcc
    39541 tttttcatca atcttgataa ccttaacatc aacttcatcc ccgatttcta ccaaatcctc
    39601 tacacgattg gtacgagtcc aagccatctc agagatatga acaagggcat ctgtcttatc
    39661 aaagaggtta acaaaggcac caaatttctc gatacgaacg actttagcac ggtaaacttc
    39721 atccactttg gcttcacgaa ccaaaccagc aataatttct ttggcacggt taatagcatc
    39781 ttggtcacta gagtagatag acacatttcc ttcttcgtct atatcaatct taacacctgt
    39841 ttcagcaata atcttgtcga tggtttctcc acccttaccg atgacaatct taatcttgtc
    39901 cacatcaatc ttgatcgtat caattttcgg agcagttgga gccaattctg gacgaacttc
    39961 tggaatggtt gcttcaatga catcaaggat ttcaaaacgc gctttcttgg cttgagcaag
    40021 agcctccgtc aagatttctg cagtaatccc ttgaatcttg atatccattt gaagggctgt
    40081 aatcccatca cgagtacctg caaccttgaa gtccatatct ccaaagtgat cttccaaacc
    40141 ttggatatct gtcaatactg tgtagttatt tccatctgag ataagtccca tagcaatacc
    40201 agctactggc gccttgattg gcacaccacc agccataagg gcaagagttc ccgcacagat
    40261 agaagcttga gatgaagaac cgtttgattc caaaacttct gctactagac ggatagcgta
    40321 tgggaattct tccaagcttg gcaagacttg agcaagagca cgctcaccaa gagcaccgtg
    40381 accgatttca cgacgacctg gcgcaccgta acgacctgtt tcccctacag aatattgagg
    40441 gaagttatag tggtgcataa agcgtttctt gtactctgga tccaaaccat caatgatttg
    40501 agtttctccc atcggagcca aggtcaagac tgaaagagct tgagtttgcc cacgagtaaa
    40561 gagacctgaa ccatgtacac gaggaaggaa gtcaacaacc gcatccaaag gacggatttc
    40621 atcgacctta cgaccatcag gacgcacctt gtcttctgta attaaacgtc gcacttctgc
    40681 gtgttccatt tgttccaaga tttcagccac atcacgcata atacggtcaa attcttcgtg
    40741 gtccgcatat ttttcttcgt aaacggcagt cacttggtct ttcactgctt gagttgcagc
    40801 ttcacgggcc aatttctctt ctacttgaac tgccttttgg aggtcactgt tgtaggctgc
    40861 aatgatttca gcttgcaatt cagcatccac gtgaagcaat tccacttctg ctttttcttt
    40921 accgacagca gcaacgattt cttcttggaa ggcaatcaat tctttgacag cttcgtgccc
    40981 tttaagaagc gcttccaaca tgatttcttc tgacaattct ttggcaccag actctaccat
    41041 gttgatagcg tgcttggttc cagctactgt caattcaaga agagattgct ctgcttgttc
    41101 ttgacttggg ttgatgatga tttggccatc tacatatccc acttgtaccc cagcaattgg
    41161 tccgtcaaat ggaatatctg aaatagacag tgccaaagat gaaccaaaca tagcagccat
    41221 tggtgcagat gcattttcat cataagaaag cactgtattg atgacttgga cttcattacg
    41281 gaaaccttcc gcaaacatag gacgaatcgg acggtcaatc aaacgcgctg tcaaggtcgc
    41341 atctgttgaa ggacgtcctt cacgtttcat aaagccacca ggaaacttcc cagccgcata
    41401 cattttttct tcgtagttga cttggagtgg gaagaaatcc ccagttgcca ttttcttaga
    41461 cataacggca gcagtcaaga cagttgactc accgtaacgt acgacaacag atccatttgc
    41521 ttgcttagca acctgaccag tctctacaat taactcacga cccgcaaaag tcgtttgaaa
    41581 cacttgtttt gccattttaa tcccctttgg attgatgaaa ttatacgcct tgcctacaaa
    41641 gatcaagata ccaaggacgt caaaagcaaa gtaaaaatag gaaactgacg aagtcttcga
    41701 tgaagacaag acagtttatc ttttttacac agcttttcgg ccgtgttcaa ttacacaaga
    41761 tattttggac ggttcggctt gccgaacatt tctgtagaaa aataggaagg tgacgtcgca
    41821 ctcgacgagt gctaggaagc ttatcttttt tcctaagaaa tgagaccaaa attcaagtca
    41881 tcaagatacc aagccgtcaa gcaactcaaa ggaagatagg aaatcgaacg acggagcgac
    41941 tgctcctagg gagatttatc tttttccaca gagttgtagg caagttcagt tttcaagata
    42001 catcattaga aaggtttaat actaaagtat ctaaagcttt cacgctaatc gctatcgggc
    42061 gattagctaa atgctttact aactctctcg tcaaataaca tcgatttgac tcactcgtgt
    42121 cgttaaatct tacagtttaa atgcattgta ttatttaata ccttcatctt tgtatcaagt
    42181 acgtacagaa tctattttat catatttttc ttaaaaagtg aggtctttac cattaaaaag
    42241 gaaccattcc cctcacctga gaagaatggt ttgcttttat tatcctagag actggtgatt
    42301 aaacaaggca tgggttgctt gatggatgta ttttgctgta tcagcattat tcatcgtata
    42361 gagatgcaca ccggcaacat cctgagttac caagtccacg atttggtcca ctgcataggc
    42421 aagtcctgct gctctgagcg actcagggtc atgctcatac ttgtctaaga tggctttaaa
    42481 tttgcgtgga agatggatat tctcacaagt cttcaagagt cggagagcct gatttcgatt
    42541 cagaattggc ataattcctg catgaatggg aacatcaatc ccagccaaga tgcacttgtc
    42601 ctgaaaatca tagaagcgct cattgtcaaa gaagagctga gttacgaggc tcgaacagcc
    42661 tgcatccact ttcttcttaa gattttgaat atctgaaatc tgatttggcg aatctggatg
    42721 cccttctgga tagcaagctc caataatatc aaagtgaggg gtttgttcct tgataaactc
    42781 aatcaagtcg gttgcatagc ggaaatcctt ttgtggttcc acgtctggaa taatatcccc
    42841 acgaagagcc aagattttct gcaccccaac tttgtccaag tcagcaatag tttcagcaac
    42901 cttgtcctta gttagataaa tagctggcaa gtgggcaatg gtcggaatcg ccaaatcatt
    42961 ttggataaag tcagccaaac gaaccgtcgt ttccttgata ttaaatttat tattgctggc
    43021 agttatactg ataaaatggg gagccaactc ctgcatatac tgcaaggctg aaataatgtt
    43081 accattaccc acggctgggt ttggagggaa cacttcaaat gagagtgacg gtgtttggcg
    43141 tgacatatgt aataaccttt tctagttgat ttctttttga acaaccactg tatggagaga
    43201 aatccaatct tacaatttct cacgcgcagc tttagctgct tcaacaaggc ggatcaagct
    43261 ttcttttgtt tctgggatac cacgtgtttt caaaccacag tcagggttga tccaaacttt
    43321 cttgcttggc actttagcaa ggatggcttc gattgtgttg tcgatttcgc cttcatttgg
    43381 tacacgaggt gagtggatat cgtaaacccc aggtcccact tctgtttgga agtttttcgc
    43441 tttgagttcg tccaagattt caaggtttga acggctagct tcaaaggaaa taacgtctgc
    43501 atccatgtta tcgatagctg ggatgatatc tgtaaattct gagtaacaca tgtgagtgtg
    43561 gatttgtgtg tctggcgcta ctgttgagtg taccaagcgg aaggcaggaa tagcccagtc
    43621 aaggtagtct tcgtaccagt cgctacggcg gagtggcaat ttttcacgaa gagcagcctc
    43681 gtcgatttgg atgattttca caccagcagc ttcaaggtca agtacttcat ccttgatagc
    43741 aagggcgatt tggagagttg aatccttgat agagatgtct tcacgtggga atgaccagtt
    43801 aaggatggta acaggtccag tcaacatacc tttaacaggt ttgtttgtac gactttgtgc
    43861 atagctagac catttaacag tgatagggtt aagacgagtg acatcacccc agatgattgg
    43921 tggttttacc ccacgcatac cgtatgattg tacccatcca tttttagaga agaggtatcc
    43981 tgacaagttt tgaccgaagt actcaaccat gtcattacgc tcaaattcac cgtgaacaag
    44041 gacatcaaag tcaatatctt cttgccactt gatccattcg tcaatcgttt cagcaaggaa
    44101 agcatcgtac tctttttgag acaattcacc tttacggtaa gccaaacgtt tggcacgaac
    44161 ttcttttgtt tgagggaatg aaccaatcgt tgttgttgga agagctggaa gtttgaaagc
    44221 ttcttcttgg atagcttcac gttctgcaaa ggctggcaaa cgagtgtagt ctgtgtctgt
    44281 caagccagcg atacgcgcac gaagttcagc attttcacca acacgctcag tcgcaaagag
    44341 ttctttgttg gctgcaagag cttctgaacc ttgaccattg cggatagcat ccaagtcacg
    44401 gatttcatcc aatttttcaa ctgcaaaggc aaagtggttc aagagtgctg gttcaaattc
    44461 ttcattagca gttgtaaatg gcacatgaag aagtgagcaa gagcttgtca aaacgatgtt
    44521 ttcagctggg atttgctcaa gaacagccaa gctcttttca tagttgttgc gccagatgtt
    44581 tttaccattg acaatacctg catagagagt cttgtcagct gggaagccac ctttaacgag
    44641 ttcaagagtt ttcttacctt caacaaagtc aaaaccgata gcatctactg gcaagtttac
    44701 aaggtcagcg tatacgtcac gaacatcacc gaaataagtt tgaagcaaga cttcaagacc
    44761 ttttttgtca gccaagagtt tgttgtaaag attcaagaag agagcttttt cttcagctgt
    44821 caagtctttt acaagagccg cttcatccaa ttggatgcaa gtcgcaccaa gttcagccaa
    44881 tttagcaaaa acttcttggt aagcagccac taagctatct acgaagtcgt ctgctttcac
    44941 gccttcttca aagtctgaca attgaaggaa agtgaaggga cctacaagaa caggacgagt
    45001 gttcaatcca agttctttgg cttcttggaa ctcatcaaaa atcttgtgac cagccaattt
    45061 tacttgagtg tctttttcaa atttaggaac gatgtagtgg tagttagtgt taaaccattt
    45121 cttcattggg agggcgcgaa cgtccccttt ttctccctgg taaccacgtc ccaaagcgaa
    45181 gtagcgctca aggtcagaca agtccaagtt ttgaacggat gcaggcacca cgttgaaaag
    45241 gaaagccgca tctaggaagt tatcatagtg agaaaagtca tttgatggaa tttcagtgat
    45301 gcctttttct ttgacaatgt tccagtgttt agcacgcaag tcttttgctg ctgctaaaag
    45361 ttcttcttct gagatttctt ttctaaagta tttttcagtt gtaaatttta attcacggaa
    45421 ttcgcccaaa cgagggaaac cgacgattgt agttgacatg atgtgtcctc caaaatttgt
    45481 tgttgaaact atcttaacag aaaagaaagc gtctgtataa ttgtaaaaaa ttagggtttg
    45541 atatagtttg aaactatata tctgtttcgg acaaaagaaa aagacttgaa gcaaacgtct
    45601 caaatccttt gtatagcttg ttttatagct ttatttcagt tagacggttc aaacgcgtta
    45661 ttagtaattc ttataagtga ctatggcttg ttattagaaa agactataac tgattctagt
    45721 caactttttc cctgttcaag tgggacgact gctagtgtct ttcctaaact ggctaggact
    45781 tttaagactg tatccaactg aggactagtc tttcctgtct ccatcctagc tatgacaggc
    45841 tggcttattc cactgacttc ttccagcttt ttctgactga ttccttgttc atacctagcc
    45901 tcaatcaact cgctcatgat agccactcgc atatcacttt caaggatttc ctccttgcta
    45961 aagagctcag atggacatcc ttccaattac tcccaatagc actattcttc atcacttaac
    46021 cctctttttt ttacgtctat gtatttttaa aaaaatgagc gaattatgat tcgatagatt
    46081 gaccagtggg tttaaagttg gtgctagcct atttcttaag cgattttcct tttctaggat
    46141 aaagcatatc ctgcttgctt aaccccaatt ttccacgatg aatccaatag taaatggttg
    46201 aaattcccac gttaacccct ttaaccataa ccatcatttc aggcgaaaat ttttggttat
    46261 gtatagtgga gaatcttttc ctttagtttc ttaagactgt tgagcgtagt cggcagaata
    46321 aatctctttg aagcgccctt ttccaagaca ttgtcggact gtcccacgct ttatttcagt
    46381 gtggatagtt tgaggagctt ttccaagtag agaggcaatt tctctatttg attttccttc
    46441 ttttttccat cgttcgatta agcgacggct atcgattgtc aaatgtttgc cttttgtagt
    46501 ataattgtct tgcatttctg tgccttttaa tcatttcaat cttaaattgg acttttttta
    46561 cttgggttgt acttaatcta taaggaagac aataaaaaga atatcaatca agtaaagtca
    46621 caaagtcaca ttagctccga gcaaccattg caaatcgagg tactcacaca atgattaaaa
    46681 catttctctc tgccctttcg gtcattctct ttgttatccc tatcatagct tattcttttt
    46741 ttccatcttc taatcttaat atttggctat ctaccagacc tatcttggca cagatttatg
    46801 ccttcccctt agctactgca actatggctg ctattttaag tttcttattt tttttcctat
    46861 ctttttacaa gaaaaataaa caaatacggt tttactctgg cattttgctc ttactatcgc
    46921 tcatattact attattcgga acagataaaa ccctttcttc tgcatcaaat aagactaaaa
    46981 ccttaaaatt agtaacttgg aacgtcgcta atcaaataga agcacaacat attgagcgaa
    47041 tttttagcca ttttgacgcc gatatggcta tattccctga actagctacc aatatcagag
    47101 gtgagcaaga aaaccagaga atcaaactat tgtttcatca agttggactt tctatggcca
    47161 actatgatat tttcacttct ccacctacca atagtggaat agctcctgtg actgtgattg
    47221 tcaagaaaag ttatggtttc tatacagaag ctaaaacttt tcatacaaca cggttcggga
    47281 caattgtatt acattcgaga aaacaaaata taccagatat cattgccttg catactgctc
    47341 ctcctctgcc aggtttaatg gaaatctgga agcaagactt aaacatcatt cataatcaat
    47401 tggcttcaaa atatccaaag gctattattg caggtgattt taatgcaact atgcgtcatg
    47461 gagcacttgc aaaaataagc tctcataggg acgcattaaa tgtactgcca ccttttgaaa
    47521 gaggaacttg gaatagccaa agtccaaaac tttttaatgc aacaatagat catattttat
    47581 tgcctaaaaa ccactactat gttaaagatt tagacattgt aagttttcaa aactctgatc
    47641 atagatgtat ttttacagaa atcacatttt aattatttta tataaaatca cccctctagt
    47701 gttcataaac tagaggggga atttgtatca tactatcgtt taacgcactt ctgcattgac
    47761 tttttcttcg agcgatgctt ggattttttc catatagcgt gcgacttctt cgtccgttaa
    47821 gctatcttct ggattttgga aggtcaagct ataagccatt gacttcatac caagtcccaa
    47881 tttctcacct gagaagacgt caaagagttt gatatctgtc aaacgtttca cgccggcagc
    47941 ttggatagca tctacaactt cttgatgagt cacttctgcc ttgaggagaa gggcaacgtc
    48001 acggctgact gccgggaatt tggtgatttc tacaaatgga gtcgctggct gaagcgcagc
    48061 ttcgatagct gaaaggttaa gctcagccac atacgtttct ggaatatcgt aagccttggc
    48121 agtgactgga tgcacttggc caaggaaacc aagaacttgg tcaccgagtg aaatcacggc
    48181 tgtacgacct ggatgaaggc tagcgatttc agatgttgct gtataggtta cttggagtcc
    48241 caaacgagta aatagggctt caaggattcc cttagcatag aagaaatcaa ctggaactgc
    48301 tgctgtttgg aaatcttttt cagcaaccaa gcctgtcaag gcaaaggcaa aactgttgat
    48361 ttcatttgga agttcttctt ttggattacc tgtttgttca aagacttttc caatctcgta
    48421 aagggccaag tttttattct tacgagccac gttgtaggca acggtatcaa ggatacctga
    48481 aatcatattt tgacggagga ctgaacgatc cacagtcatt ggccacatga gttccgtaag
    48541 gttacttggt tgagccgtaa actcaactgc tttttcagga gttgttagag tataggtgat
    48601 gatttctgtc aaacctgctc cttcagcaat agtacgaact tgacggcgga gtttttgtgt
    48661 ggctgtcaat tcacctgctg taccatcgtc ttttggtaga ctagttggca agcggtcata
    48721 accatagata cgagcaattt cttcaaagag gtcagcttcg attgtgatat cccaacgacg
    48781 acgtgggact ctgactgtaa agctgtctgc atttccagaa agaccaaagc caagacgacg
    48841 gaagacgtct tctacatcag cataagacag ctcagttccg aggacacggt taacatcagc
    48901 aagggttgaa gaaacttcta catctgaagt atcaagctca cccgctgaaa cgatgccctt
    48961 acgcaccgtc gcacctgcaa gttccgcaat caggctagct gccgcatcaa gggcttcatt
    49021 aactgttgcc acattaattc ctttttcaaa gcgagaagat gactcagaac gaaggttcag
    49081 gcgaccactt gtcttacgga tagatttgcc attgaaaaca gcagcttcaa ggacaacacg
    49141 actagatttt tcagagattt ctgttgcttg accacccatg acacctgcaa gggctactgg
    49201 cttgtctgcg acagtgatga ctaggtcatt cacgtccaag tcacgttctt caccgtccaa
    49261 ggtcaccaat ttttcaccag cacgcgcttc acgcacacgg atgtcagtcc cttcaaagtt
    49321 atccaagtca aaggcatgca ttggttgacc aaaatagagc aggatgtagt tggtcacgtc
    49381 cactacgtta ttgatgggac ggattccttc gttcatgaga aggttttgca accattgtgg
    49441 acttggtgcg atggtcacat tgtccaagat acgagctgca tagtaaggcg ccttgtctgt
    49501 ctcaatgctg acagaaaggg catctgccgc agcttcatta gtttctgtta gagtaaattc
    49561 tttaaagttg actgccttgt catagatggc tgccacttcg tgagccactc cacacataga
    49621 aagggcatct gcacggtttg gtgtgatgga aagttcgatg atttcatcat ccaagtctag
    49681 gtaagaaaag acttcctcac ctggcacggc atcttcaggc aagatttgga tgccatctgc
    49741 gaattcctta ggcacaactg agtcagaaat tcccaattca ccaagtgaac agatcattcc
    49801 aagtgactcc aaaccacgga tttttccttt tttgattttg tagttatcag cgatacgagc
    49861 tcctggaaga gccaccatga ccttgatccc agcacgcaca tttggggcac cacaaacgat
    49921 ctgacgctct tcttcgccaa cgttaacctg acaaacatgg aggtgagtct ctggcacatc
    49981 ttcgcaagac aagacctcac cgacgacaat ttttgagaga ccagcagctg gtgattcgac
    50041 accctctacc tcgattcctg tagttgacat tttttcagcc aactcttgtg atggcacatc
    50101 aatgtccacc aattctttta accatttata agatataagc ataatttagt tctccagaat
    50161 gaccattgcc acactggttc ttttcctttc ctatcatttc aatagaagaa tcctcttctt
    50221 accttaattt ctttctcagt aaccaatccg tatctacttt ttgaccaacc ataaaatgat
    50281 gttggctaaa tttttcaaaa ccatatcgat tataaaaggc ttgagctttt gtattatgct
    50341 cccaaacacc tagccaagcc caagaaaaac tattttttgt agcaagttca agtgcgaatt
    50401 caaacagttg cttacctagt ccaaatcctt ggaatttttg tagcacatag aggcgttgaa
    50461 tttcaaaagc gtcctctaat tctctctcag tttgagcact tccccagttg actttgagaa
    50521 aaccagctat ctcctcctca tgcataatga aataggtttc agagtcagga tttcccaact
    50581 cagttgacaa agttttcaga ctataagcct cttcaaagta ttcctgtaac tgctcttccg
    50641 tattatcata cgcaaaggtt tcacgaaagg tttgtttggc aattttagcc aacacctcaa
    50701 catctgccat ttctactttt ataatcatta tttaaactgt tctgagaagc ggacatctcc
    50761 ttggtagaat ccacggatat cgttgattcc ataacggagc atagctacac gctcttgtcc
    50821 aagaccaaag gcaaagccag agtatacagt cgcatcgata ccactcattt caaggacacg
    50881 tgggtgaacc ataccggccc ccataatttc gatccaacct gttttcttac atatattaca
    50941 gccttctcca ccacacttga agcaagaaac atccacctca acagatggct ctgtgaatgg
    51001 gaagtaagat ggacgcaaac gaatttgacg ctcttcacca aacatttttt ggacaatcaa
    51061 ctgaagcgtt ccttgaagat cagccataga gatatttttc ccaactacca agccttcgat
    51121 ttggtggaat tggtgactgt gggtcgcatc gtccgtatcg cgacggaaga cacgccctgg
    51181 cgagatcatc ttcaaaggac ctttagaaaa atcatgggca tccatagcac gcgcctgaac
    51241 tggagacgtg tgggtacgga gcaagatttc ttcagtgata tagaaagtat cctgcatatc
    51301 acgagctggg tggtcttttg gaaggttcat acgttcaaag ttatagtagt cttgctccac
    51361 ttcaaaacca tccacgactt gataacccat accgatgaag atatcttcga tttcttcact
    51421 ggtttgtgtc aaaacgtgac ggtgaccagt cgcaactgga cgacctggaa gcgtcacatc
    51481 gatactctcg ctagccagtt gagccgcgac tttcttttct tccaagagct tagctgtttc
    51541 ttcaaaagca gcagtcaaga catcacgagc ttcattgacg tgtttcccga tgattggacg
    51601 catctcagca gaaacatctt tcatcccttt gaggatttca gtgagcgaac cctttttacc
    51661 aaggacagag acacgcaaat cttgcatctc tttttcattt ccagcagtaa tctgcttcaa
    51721 gctagccagc gtttcttcgc gaagcgcttt taattgttct tcaatagttg acatatttcc
    51781 tccatcagtc tctcgtagat aaaaagaaaa ccacatgcca aaaactccac tcggagcgtt
    51841 gacacgcggt accatccgtt ttcatctgac aagtcagacc ttcatttcta aatccatgcg
    51901 caagtgaatt cacccagctt tcatatagag agcttgcagt cacggctctc ctccctgata
    51961 tacttccctt gggctactag tctttcagat tcctattcaa ttactactta gtttatcaga
    52021 tttttaccat tcttgcaaga cctatcttac ttctgcttgt tagcttattc ttatctaact
    52081 ttatagcgga ttgaaataag atgaaaacaa atcgattggg aaagtaaaat ta
//
LOCUS       DAVKZI010000011        45780 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKZI010000011 DAVKZI010000000
VERSION     DAVKZI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.011"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..278
                     /locus_tag="VXB18_000746"
     CDS             <1..278
                     /locus_tag="VXB18_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0381979.1"
                     /translation="SWYYLNSNGAMVTGWLQNNGSWYYLNANGSMATGWVKDGDTWYY
                     LEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(480..1736)
                     /locus_tag="VXB18_000747"
     CDS             complement(480..1736)
                     /locus_tag="VXB18_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0381980.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKIAVAETSLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRIHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSRA"
     gene            1939..3174
                     /gene="pspC"
                     /locus_tag="VXB18_000748"
     CDS             1939..3174
                     /gene="pspC"
                     /locus_tag="VXB18_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HEV0381981.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALV
                     NQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPE
                     TPQPENPEHQKPTTPSPDTKPSPQPEGKKPSVPDINQEKEKAKLAVVTYMSKILDDIQ
                     KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFK
                     KGLTQDTPKEPGNKKPFAPKPGMQPSPQPEVKPQPEKPKPEVKPQPEKPKPEVKPQPE
                     KPKPDNSKPQADDKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTGSISNLALE
                     IAGLLTLAGATILAKKRMK"
     gene            complement(3393..4373)
                     /gene="dusB"
                     /locus_tag="VXB18_000749"
     CDS             complement(3393..4373)
                     /gene="dusB"
                     /locus_tag="VXB18_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0381982.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(4360..5232)
                     /gene="hslO"
                     /locus_tag="VXB18_000750"
     CDS             complement(4360..5232)
                     /gene="hslO"
                     /locus_tag="VXB18_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0381983.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            5397..6824
                     /locus_tag="VXB18_000751"
     CDS             5397..6824
                     /locus_tag="VXB18_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0381984.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQMTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            6983..8491
                     /gene="glpK"
                     /locus_tag="VXB18_000752"
     CDS             6983..8491
                     /gene="glpK"
                     /locus_tag="VXB18_000752"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0381985.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            8533..10359
                     /gene="glpO"
                     /locus_tag="VXB18_000753"
     CDS             8533..10359
                     /gene="glpO"
                     /locus_tag="VXB18_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0381986.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            10429..11133
                     /locus_tag="VXB18_000754"
     CDS             10429..11133
                     /locus_tag="VXB18_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0381987.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            11430..11633
                     /locus_tag="VXB18_000755"
     CDS             11430..11633
                     /locus_tag="VXB18_000755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381988.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(11720..12328)
                     /locus_tag="VXB18_000756"
     CDS             complement(11720..12328)
                     /locus_tag="VXB18_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0381989.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGTGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            13415..14692
                     /gene="ltrA"
                     /locus_tag="VXB18_000757"
     CDS             13415..14692
                     /gene="ltrA"
                     /locus_tag="VXB18_000757"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0381990.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYFRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     YFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGFLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            15148..16326
                     /locus_tag="VXB18_000758"
     CDS             15148..16326
                     /locus_tag="VXB18_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0381991.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            16640..16771
                     /locus_tag="VXB18_000759"
     CDS             16640..16771
                     /locus_tag="VXB18_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0381992.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            16792..18342
                     /gene="dltA"
                     /locus_tag="VXB18_000760"
     CDS             16792..18342
                     /gene="dltA"
                     /locus_tag="VXB18_000760"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0381993.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            18339..19583
                     /gene="dltB"
                     /locus_tag="VXB18_000761"
     CDS             18339..19583
                     /gene="dltB"
                     /locus_tag="VXB18_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0381994.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            19597..19836
                     /gene="dltC"
                     /locus_tag="VXB18_000762"
     CDS             19597..19836
                     /gene="dltC"
                     /locus_tag="VXB18_000762"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0381995.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            19829..21097
                     /gene="dltD"
                     /locus_tag="VXB18_000763"
     CDS             19829..21097
                     /gene="dltD"
                     /locus_tag="VXB18_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0381996.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            21252..21692
                     /gene="adcR"
                     /locus_tag="VXB18_000764"
     CDS             21252..21692
                     /gene="adcR"
                     /locus_tag="VXB18_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0381997.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            21692..22396
                     /locus_tag="VXB18_000765"
     CDS             21692..22396
                     /locus_tag="VXB18_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0381998.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHNAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            22389..23195
                     /locus_tag="VXB18_000766"
     CDS             22389..23195
                     /locus_tag="VXB18_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0381999.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            23205..24710
                     /gene="adcA"
                     /locus_tag="VXB18_000767"
     CDS             23205..24710
                     /gene="adcA"
                     /locus_tag="VXB18_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0382000.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(25839..26612)
                     /locus_tag="VXB18_000768"
     CDS             complement(25839..26612)
                     /locus_tag="VXB18_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0382001.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            26788..28191
                     /locus_tag="VXB18_000769"
     CDS             26788..28191
                     /locus_tag="VXB18_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0382002.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLLSQGKINEDTELK
                     DIMTNIAETQYYYPQLS"
     gene            28220..29512
                     /locus_tag="VXB18_000770"
     CDS             28220..29512
                     /locus_tag="VXB18_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0382003.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLVAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWDDFTQAMASIRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVQTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            29599..30528
                     /locus_tag="VXB18_000771"
     CDS             29599..30528
                     /locus_tag="VXB18_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0382004.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIFCINILFRERKRLKGGK"
     gene            30531..31370
                     /locus_tag="VXB18_000772"
     CDS             30531..31370
                     /locus_tag="VXB18_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0382005.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            31367..32686
                     /locus_tag="VXB18_000773"
     CDS             31367..32686
                     /locus_tag="VXB18_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0382006.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRDENTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            32692..34563
                     /locus_tag="VXB18_000774"
     CDS             32692..34563
                     /locus_tag="VXB18_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEV0382007.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIKNVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            34585..36801
                     /locus_tag="VXB18_000775"
     CDS             34585..36801
                     /locus_tag="VXB18_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0382008.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLLQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            36812..39829
                     /locus_tag="VXB18_000776"
     CDS             36812..39829
                     /locus_tag="VXB18_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEV0382009.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLIIKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     DSYDQPSLNFDQKNHMVNITINSNGNLEFELHF"
     gene            39844..40572
                     /locus_tag="VXB18_000777"
     CDS             39844..40572
                     /locus_tag="VXB18_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEV0382010.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            40585..42351
                     /locus_tag="VXB18_000778"
     CDS             40585..42351
                     /locus_tag="VXB18_000778"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0382011.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDSG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            42497..43648
                     /locus_tag="VXB18_000779"
     CDS             42497..43648
                     /locus_tag="VXB18_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0382012.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            43792..44676
                     /locus_tag="VXB18_000780"
     CDS             43792..44676
                     /locus_tag="VXB18_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0382013.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            45050..45301
                     /locus_tag="VXB18_000781"
     CDS             45050..45301
                     /locus_tag="VXB18_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0382014.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            45289..45579
                     /locus_tag="VXB18_000782"
     CDS             45289..45579
                     /locus_tag="VXB18_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382015.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEDKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT        14422 a         7794 c         9735 g        13829 t
ORIGIN      
        1 gttcatggta ctacctaaac agcaatggtg ctatggtaac aggatggctc caaaacaatg
       61 gctcatggta ctacctaaac gctaacggtt caatggcaac aggttgggtg aaagatggag
      121 atacctggta ctatcttgaa gcatcaggtg ctatgaaagc aagccaatgg ttcaaagtat
      181 cagataaatg gtactatgtc aatggctcag gtgcccttgc agtcaacaca actgtagatg
      241 gctatggagt caatgccaat ggtgaatggg taaactaaac ctaatataac tagttaatac
      301 tgacttcctg taagaactct ttaaagtatt ccctacaaat accatatcct ttcagtagat
      361 aatataccct tgtaggaagt ttagactaaa aaataactct gtaatctcta gctggattta
      421 tagcgctaga gactacggag ttttttggct ctttgtcaac tgtagtgggt tgaagtcagc
      481 taagctcgag aaaggacaaa ttttgtcctt tcttttttga tattcaaagc gataaaaatc
      541 cgttttttga agttttcaaa gtttcgaaaa ccaaaggcat tgcgcttgat aagtttgatg
      601 agattattgg tcgcttccag tttggcatta gaatagtgta gttgaagggc gttgacaatc
      661 ttttctttat ctttgaggaa ggttttaaag acagtctgaa aaagaggatg aacctgcttt
      721 agattgtcct caataagccc gaaaaatttc tctggttcct tattctggaa gtgaaaaagc
      781 aagagctgat agagctgata gtggtgtttc aagtcttccg aataactcaa aagcttgttt
      841 aaaatctctt tattggttaa atgtatacga aaagtaggac gataaaatcg cttatcactc
      901 agtttacggc tatcctgttg aatgagtttc cagtagcgct tgatagcctt gtattcatga
      961 gactttcgat ccaattgatt catgatttga acacgcacac gactcatagc acggctaaga
     1021 tgttgtacaa tgtgaaagcg atccaacacg attttagcac acgggaaaag ttgtctagct
     1081 aagtcatagt aagggctaaa catatccata gtaataattt tgacgcgaca tcggacggct
     1141 ctatcatatt taagaaagtg atttcgaatg atagcttgtg ttcttccctc aagaacagtg
     1201 atgatattga gattgttaaa atcttgcgca atgaagctca tctttccctt tgtaaaagca
     1261 tactcatccc aagacataat ctcaggaaga caagaaaaat catgtttaaa gtgaaaatca
     1321 ttgagcttac gaataacagt tgaagttgag atggaaagct gatgggcaat atcagtcata
     1381 gaaatctttt caatcaactt ttgagcaatc ttttggttga tgatacgagg gatttggtga
     1441 tttttcttga cgagggaagt ctcagcgacc gctatttttg agcactgata gcacttgaat
     1501 cgacgctttc taaggagaat tctagtaggc ataccagtcg tttcaagata aggaatttta
     1561 gaaggttttt gaaagtcata tttcttcatt tgacttccgc actcagggca agatggggcg
     1621 tcgtagtcca gtttggcgat gatttccttg tgtgtatctt tattgatgat gtctaaaatc
     1681 tggatattag ggtctttaat gtctagtaat tttgtgataa aatgtaattg ttccatatga
     1741 ttctttctaa tgagttgttt tgtcgctttt cattataggt catatgggac tttttttcta
     1801 cacaaaatag gctccataat atccataggg gatttaccca ctacaaatat tatagagcca
     1861 aataatgtag caaatttcat atacaattca tattagcagg atatactgta gttaattaaa
     1921 attatggaga atatagacat gtttaaatca aatcatgagc gaagaatgcg ttattccatt
     1981 cgtaaattta gtgtaggagt agctagcgta gctgttgcca gtctttttat gggaagtgtt
     2041 gtacatgcga cagagaaaga gggaagtacc caagcagcca cttcttttaa taggggaaat
     2101 ggaagtcagg cagaacaacg tggagaactc gatttagaac gagataaggc aatgaaagcg
     2161 gtcagtgaat atgtaggaaa aatggtgaga gatgcctatg taaaatcaga tagaaaacga
     2221 cataaaaata ctgtagctct agttaaccag ttgggaaaca ttaagaacag gtatttgaat
     2281 gaaatagttc attcaacctc aaaaagccaa ctacaggaac tgatgatgaa gagtcaatca
     2341 gaagtagatg aagctgtgtc taaatttgaa aaggactcat tttcttcgtc aagttcagga
     2401 tcctccacta aaccagaaac tccgcagccg gaaaatccag agcatcaaaa accaacaact
     2461 ccatctccgg ataccaaacc aagccctcaa ccagaaggca agaaaccaag cgtaccagac
     2521 attaatcagg aaaaagaaaa agctaagctt gctgtagtaa cctacatgag caagatttta
     2581 gatgatatac aaaaacatca tctgcagaaa gaaaaacatc gtcagattgt tgctcttatt
     2641 aaggagcttg atgagcttaa aaagcaagct ctttctgaaa ttgataatgt aaataccaaa
     2701 gtagaaattg aaaatacagt ccacaagata tttgcagaca tggatgcagt tgtgactaaa
     2761 ttcaaaaaag gcttaactca ggacacacca aaagaaccag gtaacaaaaa accatttgct
     2821 ccaaaaccag gtatgcaacc aagtcctcaa ccagaggtta aaccgcaacc agaaaaacca
     2881 aaaccagagg ttaaaccgca accagaaaaa ccaaaaccag aggttaaacc gcagccggaa
     2941 aaaccaaaac cagataatag caagccacaa gcagatgata agaagccatc aactacaaat
     3001 aatttaagca aggacaagca accttctaac caagcttcaa caaacgaaaa agcaacaaat
     3061 aaaccgaaga agtcattgcc atcaactgga tctatttcaa atctagcact tgaaattgca
     3121 ggtcttctta ccttggcggg ggcaaccatt cttgctaaga aaagaatgaa atagtgattg
     3181 attcattcaa aaatgtttgt aaaaagtatt cggcttaaaa gaaaagagtc tgggataaaa
     3241 agattttgat tttaggaatt ctttattata aatttttaaa atcgatagat tagacaaaaa
     3301 agcgaacaag acagaattct gagtgtcaga taactgattt tgttcgcttt ttatatttaa
     3361 tattatactt ttgtcctagg ctcttttttg cattatactt tttccaattg caagagggct
     3421 tcaatctctg ccagggtgct agcttgcgaa atggctccac ggagtttggc agcgccagat
     3481 gttccacgga ggtagtgagg agcgaggccg cggaattcac gaactgcgac gttttctcct
     3541 ttgaggttaa tcaatcgttt caagtgttcg taggcgatct tcatcttgtc ttcaaaggtc
     3601 aaatcaggta ggatttctcc tgtttcaaag taatggttga tttggttgaa gaggtaagga
     3661 tttcccatgg cagctcggcc aatcatgact gcgtcagcac caacttcttc gatgcgttgc
     3721 ttggcttctt ggacagtacg gatatcaccg ttggcgatga atggaatctt ggttagagct
     3781 tgggcaacct tgtaaagggt ctcaaggtct gcgtggccag tatacatttg ttcacgggta
     3841 cggccatgca tggcgagggc agaaacacct gcagcttcag cagcgagggc attttctact
     3901 gccagagatg ggtccgccca tccggtacgc attttgacag taagggggat atcaaggaca
     3961 gactggacct tgttgatgat agagtagatc ttgtcaggat ccttgagcca catagcacca
     4021 gcttcgttct tcacgatttt gttgacaggg cagcccatgt tgatatcgac gatatcggtc
     4081 ttggtatttt cttggatgaa ttctgctgcg cgtgctaggc tgtcttcatc gctaccaaaa
     4141 agttggatag agacagggtt ttcgccctca tcgatatgaa gcatgtgcag ggttttttcg
     4201 ttgttgtatt ggattccctt gtcagagacc atttccatta caacgagtcc agctccgagc
     4261 tcttttgcga tggtacgaaa ggctgagttg gtcacgccag ccataggcgc taaaacggta
     4321 cgattgggaa tctcaacatt gccaatcata aaaggtgtat taagatttgt cacgaatgag
     4381 ttcctccagg tccttttcat caaagttgta agtagtttgg cagaattgac aagtgatttc
     4441 taccccgtgg tcttcctctt tcatttcctg taagtctgag cttggaaggc tggcaagagc
     4501 gttcataaag cgttcatggc tacagtcaca ttggaaacgg atttcttctt cagaaagacg
     4561 cttgtaggct tcgtccccgt agatagcctt gaggagggct tcgatatggt cgtcgctttc
     4621 gagaagagta gagatagctg gcatttcttg gatgcgtttt tcaaagcgag caatctcttc
     4681 tttcttggct cctggcaaga cttgaactag gaaaccacct gcaatcttga ccttgtcttc
     4741 ctcgtccaaa aggacattga ggccgaccgc tgaaggcgtt tgttggcttt cagtaaggta
     4801 aaaggcaagg tcttcaccga tttctccaga gatgagggga gttatagagt tgtaaggatt
     4861 tccagtaccg tagtctgtga taacgaggaa ttgaccattt ccaacaaaag gtccgactag
     4921 gacttcacca gtcgcagtct ttttgatgtc aacaccagga ttttgaacgt agcctttgac
     4981 gttccccttg gtatcagcga cggtgataat agcacctaga gagctagatc ccaacacctt
     5041 aactgtaagt ttggtatttc ctttttcatt ggctgcgaga atctggctgg cgataagagt
     5101 tcgaccaagc gctacagttg agctagcttg ggtttgatgt ttttcttgag cagtgcggac
     5161 ggtttcagtg ctatcaagga caaaagcacg aaaggctccg ctttctgata tagttttaat
     5221 aattttatcc atagctacta ttttagcata aaaatgccca aagggggagc cgtgtgttta
     5281 ctgattttca ggataatgga ccaggaaatc agcatgaaaa taaaaagaga aacagattat
     5341 tttagcattt gtaagattta tgctatgctt aaggtagaaa atgaaagggg taacaaatgt
     5401 atttaggaga tttgatggag aaagccgagt gtggtcaatt ttcaatcctt tcctttctat
     5461 tacaagagtc tcagatgacc gtcaaggctg taatggaaga aacaggattt tcaaaagcaa
     5521 ccctaaccaa atatgtcacc ctgctcaatg acaaggcttt ggatagtggc ttagagctgg
     5581 ctattcactc agaagatgaa aatctgcgtc tgtctatcgg tgcagctacc aaggggagag
     5641 atattcggag cttgtttttg gagagtgctg ttaaatacca gattttggtt tatcttctct
     5701 accaccaaca gtttttagcc catcagctgg ctcaagaatt ggtgattagc gaggctacgc
     5761 ttggtcgtca cttggctggt ttaaatcaga ttttgtcaga atttgattta tccatccaaa
     5821 atggacgttg gcgaggtcca gagcatcaga ttcgctattt ctatttctgt cttttccgaa
     5881 aggtctggtc gagtcaggaa tgggaaggtc acatgcagaa accagagaga aaacaggaga
     5941 ttgccaattt agaggaaatc tgcggtgcaa gtttgtctgt ggggcagaaa ttggacttgg
     6001 ttctctgggc tcacatcagt caacaacgtc ttcgggtcaa tgcttgtcag tttcaagtca
     6061 tagaagagaa aatgcgaggg tattttgaca atatcttcta tcttcgtttg ctgagaaagg
     6121 ttccgtcctt ttttgctggg caacatattc cactaggagt tgaggatggt gagatgatga
     6181 tattcttctc ttttctccta tctcatcgca ttcttcctct tcatactatg gagtatattc
     6241 ttggttttgg agggcagttg gcagatttac tgacgcaatt gattcaagaa atgaagaagg
     6301 aggaactatt gggggattat acagaggacc atgtcaccta tgaactcagt cagctttgtg
     6361 ctcaagtcta tctctataag ggctatattt tacaggatcg ctacaagtac cagttagaga
     6421 atcgtcatcc atatttactg atggaacatg attttaaaga gacagcagag gagatttttc
     6481 atgctctacc tgcttttcaa caggggacag atttagataa gaagattctc tgggaatggc
     6541 tccagttaat cgaatatatg gctgaaaacg gtggccagca tatgcggatt ggtctggatt
     6601 tgacatctgg ttttcttgtc ttttcaagga tggcagccat tttgaaacgg tatttggaat
     6661 acaatcgttt tattaccatt gaagcttatg accctagtcg gcattatgat ttgctggtta
     6721 ccaataaccc gattcataag aaggaacaga caccagtcta ttatttaaaa aatgacttgg
     6781 atatggagga tttggcaggg attcgtcagt tattattcac ttaaaaggct tggttaatcc
     6841 aggtcttttt tgtgaaattc acacaatctc ctcacatttt tttaaaaatt aaaaaaagtt
     6901 gataaacaag aaagcgcttt attttgtata ctagtaagtg taaagaggaa acacctcaag
     6961 atctttatca ggaggacagt atatgtcaca agaaaaatac atcatggcca ttgaccaggg
     7021 aactacaagt tctcgtgcca tcattttcaa caaaaaaggg gaaaaggtta gctcgagtca
     7081 aaaagagttt acccagattt tccctcaggc aggttgggtt gagcacaatg ccaatgaaat
     7141 ttggaactct gttcagtcag ttattgcggg tgctttcatc gaaagtggtg tcaagccaaa
     7201 tcaaatcgag gcaatcggga ttaccaacca acgtgaaaca acggttgtct gggataagaa
     7261 aacaggactt cctatctaca atgctatcgt ttggcagtca cgccagacag cacctttggc
     7321 tgagcaacta aaaagccaag gttatgtgga aaaattccat gaaaagactg gtttgattat
     7381 tgatgcttac ttctctgcta ccaaggttcg ttggattttg gatcatgtag aaggcgctca
     7441 agagcgagca gaaaaagggg aattgctctt tggtactatc gatacttggt tggtttggaa
     7501 attgactgac ggtgcggctc acgtgactga ctactcaaat gcagctcgta ccatgcttta
     7561 taacattaaa gaactcaaat gggatgatga aattttggaa atccttaaca ttccgaaggc
     7621 tatacttcca gaagttcgtt ctaactccga aatctacggc aagacagctc cattccattt
     7681 ctacggtgga gaggtgccaa tctcaggtat ggctggggac caacaagcag ccctctttgg
     7741 acagttggct tttgagccag gtatggttaa gaatacttat ggaacaggct ctttcatcat
     7801 catgaatact ggggaagaga tgcagttgtc tgaaaacaac ctcttgacaa ccattggtta
     7861 cggaatcaac ggtaaggttt attatgcctt ggaaggttct atcttcatcg caggaagtgc
     7921 tattcagtgg cttcgtgacg gtcttcgcat ggttgaaaat tcaccagaat ctgaaaaata
     7981 cgctcgtgat tctcacaaca acgatgaagt ttatgtcgtt ccagccttta caggtctagg
     8041 cgctccatac tggaaccaaa atgctcgtgg ttccgtcttt ggtttgactc gtggaacaag
     8101 caaagaagac tttatcaagg cgactttgca atctattgct tatcaagtgc gtgacatcat
     8161 cgacaccatg caagtggata ctcagaccgc cattcaagta ttgaaggtgg atggtggtgc
     8221 agccatgaac aacttcctca tgcagttcca ggcggatatt ttaggcattg atattgcacg
     8281 tgctaaaaac ttggaaacaa cagctctagg agcggccttc ctagcaggtt tatcagtagg
     8341 gtactggaaa gacttggacg agttgaaact cttgaacgag acaggagaac tctttgagcc
     8401 atctatgaat gaatctcgca aggaacaact ctacaagggc tggaagaagg ctgtgaaagc
     8461 aactcaagtc tttgcggaag tagacgacta atactggcag aataaagcga tttatttaga
     8521 aagtgtgtaa atatggaatt ttcaaagaaa acacgtgaat tgtcaattaa aaaaatgcag
     8581 gaacgcaccc tggacctctt gattatcggt ggaggaatca caggggctgg tgtagccttg
     8641 caggcggcag ctagcggtct tgagactggt ttgattgaaa tgcaagattt tgcagaagga
     8701 acatctagtc gttcaacaaa attggttcac ggaggtcttc gctacctcaa acaattcgac
     8761 gtagaagtgg tctcagatac ggtttctgaa cgtgcagtgg ttcaacaaat cgctccacac
     8821 attccaaaac cagatccaat gctcttacca gtttacgatg aagatggagc aacctttagc
     8881 ctcttccgtc ttaaagtagc catggacttg tacgacctct tggcaggtgt tagcaacaca
     8941 ccaactgcga acaaggtttt gagcaagaaa gaagtcttgg aacgccagcc aaacttgaag
     9001 aaggaaggct tggtaggagg tggagtgtat cttgacttcc gtaacaacga tgcgcgtctc
     9061 gtgattgaaa acatcaaacg tgccaaccaa gacggtgccc tcattgccaa ccacgtgaag
     9121 gcagaaggct tcctctttga cgaaagtggc aagattacag gtgttgtagc tcgtgatctc
     9181 ttgacagatc aagtatttga aatcaaggcc cgtctggtta ttaatacaac aggtccttgg
     9241 agtgataaag tacgtaattt gtctaataag ggaacgcaat tctcacaaat gcgcccaact
     9301 aagggagttc acttggtagt ggattcaagc aaaatcaagg tttcacagcc agtttacttc
     9361 gacacaggtt tgggtgacgg tcgtatggtc tttgttctcc cacgtgaaaa caagacttac
     9421 tttggtacaa ctgatacaga ctacacaggt gatttggagc atccaaaagt aactcaagaa
     9481 gatgtagatt atctacttgg cattgtcaac aaccgctttc cagaatccaa catcaccatt
     9541 gatgatatcg aaagcagctg ggcaggtctt cgtccattga ttgcagggaa cagtgcctct
     9601 gactataatg gtggaaataa cggtaccatc agtgatgaaa gctttgacaa cttgattgcg
     9661 actgttgaat cttatctctc caaagaaaaa acacgtgaag atgttgagtc tgctgtcagc
     9721 aagcttgaaa gtagcacatc tgagaaatat ttggatccat ctgcagtttc tcgtgggtct
     9781 agcttggacc gtgatgacaa tggtcttttg actcttgctg gcggtaaaat cacagactac
     9841 cgtaagatgg ctgaaggagc tatggagcgc gtggttgaca tcctcaaagc agaatttgac
     9901 cgtagcttta aattgatcaa ttctaaaact tatcctgttt caggtggaga attgaaccca
     9961 gcaaatgtgg attcagaaat cgaagccttt gcgcaacttg gagtatcacg tggtttggat
    10021 agcaaggaag ctcactatct ggcaaatctt tacggttcaa atgcaccgaa agtctttgca
    10081 cttgctcaca gcttggaaca agcgccagga ctcagcttgg cagatacctt gtcccttcac
    10141 tatgcaatgc gcaacgagtt ggctcttagc ccagttgact tccttcttcg tcgtaccaac
    10201 catatgctct ttatgcgtga tagcttggat agcatcgttg agccagtttt ggatgaaatg
    10261 ggacgattct atgactggac agaagaagaa aaagcaactt accgtgctga tgtcgaagca
    10321 gctctcgcta acaacgattt agcagaatta aaaaattaag aaaaaataaa agaggtggag
    10381 ggcagcattc cttgtcgccc gtcccttctt tttaatggag acagaaagat gatgaatgaa
    10441 ttatttggag aatttctagg gactttaatc ctgattcttc taggaaatgg tgttgttgca
    10501 ggtgtggttc ttcctaaaac caagagcaat agctcaggtt ggattgtgat tactatgggt
    10561 tgggggattg cagttgcggt tgcagtcttt gtatctggca agctcagtcc agctcattta
    10621 aatccagctg tgacagttgg tgtagcttta aaaggtgact tgccttgggc ttccgttttg
    10681 ccttatatct tagcccagtt cgcaggggcc atgctgggtc agattttggt ttggttgcaa
    10741 ttcaaacctc actatgaggc agaagaaaat gcaggcaata tcctggcaac cttcagtact
    10801 ggaccagcca tcaaggatac tgtatcaaac ttgattagcg aaatccttgg aacctttgtt
    10861 ttggtgttga caatctttgc tttgggtctt tacgattttc aggcaggtat cggaaccttt
    10921 gcagtgggaa ctttgattgt cggtatcggt ctatcactag gtgggacaac aggttatgcc
    10981 ttgaacccag ctcgtgacct tggacctcgt atcatgcaca gcatcttgcc aattccaaac
    11041 aagggagacg gagactggtc ttacgcttgg attcctgttg taggccctgt tatcggagca
    11101 gccttggcag tgcttgtatt ctcacttttc tagtttatac tcttcgaaaa tcaaattcaa
    11161 accacgtcag cgtcgcctta ccgtactcaa gtacagcttg cggctagctt cctagtttgc
    11221 tctttgattt tcattgagta ttagaaaaca attatgttga tagagcttgg gcaagagccc
    11281 aatttcagca aaaaatgaag taaatcttct cataataaaa cgcatcatat caagcacgaa
    11341 aattccacga ggtcaactac agtcagaaag ctgaacaaca agccaaaacg cccaaaaaag
    11401 gcggcaaaaa gcaagcacct gcaagcaacg tgccgaaatg gtcaaatcct gattatgtca
    11461 acgaattaga cccaaaaatc gttgatatgc tagtagaatt tcacaagtca caaggcactt
    11521 tggaaactcc cgaggcgcaa gcagaaatcg cccaaaaacg tgaagaaatc gagcaaagga
    11581 gagctgagct tgaggataaa aaacaagagc ttttgaaccg cttgaacaaa tagagtttcg
    11641 caagtattat gcttacaaat tacttgagca attaactaaa atataaaccc tgcctttata
    11701 tctaggcagg gtttatattt tagaaattca cgtaggttgt tacggttttt acatacccag
    11761 tatagtttga gtttctatag tattcagtga taaacttcca ttttctttga gcaacatgga
    11821 tataagtact tgttatgtag tatggatatg ggctttgtga atccaagtaa gactgataag
    11881 cttgtatacc aaaatatgct ccaccaatta ttgcacccca tggacccccc aataaagcac
    11941 ctatcctacc aatcatataa ctgattccag taccagtcat gaagttagcg aatgtgttag
    12001 cttgtttatt cccatgtatt gtgttgacgt aattccaaac attaggatcg tatgatctaa
    12061 aagatatatt taggtcgatt tcattctttt gataagccat ataaaatgcc ccattgatat
    12121 agacgccgtc agcacgtcgt tcaatagtgt ctacacttcc atctggattg acaacctcaa
    12181 gaacttcatc gcttaaaata tttacttgcg tatctccgaa ccgcactgat gagccattct
    12241 caaactgagc ctcaccagat acaactttag agtttgccga taagctatca tcagcaaaaa
    12301 caacaagcga cggggaaatg ctagacatac agaaaacaga cataactagc aaacacatgc
    12361 atttaaacat cttagacata acggaaactc ttttgtattt ttgatttttt tcaactttta
    12421 ttatacaata aaaccaaata aaaagaaagc ggtaacaata tgcttaatgc gaaaattttt
    12481 tatatatttt tatgtttgat cgttatcgaa actacaggct tgttgttgtt gaaaagaggt
    12541 ctcgaaatgg gttatttaga cacagaagct attatcctcg cagttttttc atttgctttt
    12601 tacaacctat gttcattcgc ttgggtctgc tctacaataa aaaacaataa aaaataaata
    12661 gacgtatttt caaaaaaaaa aatgcatatt tatcttagca aaacgacgat ttaaatcgtc
    12721 gtttttttgt agtacgacgg gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc
    12781 tgctaccggt gaacccaata gcgattccca agcctgacta tcgtgaggta gcagggagag
    12841 gaagggatag cgaaatcgtg gctctacgaa caggaacgtg atagtaaggc gtatatagcg
    12901 gataaggagg cttcaaactc taaagtccaa aaaggtagtc gtaacctata tgtgtaaatc
    12961 acgagagtaa ttgaattcgg actaaggttt gtgtgaaaaa gataaatctt tctagagtct
    13021 aaagactctg cgtcagattt cctattttca ctgtaacctt ttaacgtcct catatcttgt
    13081 ataaacgagg aaagatgtac gacttatccc gtgaggtctc atgagtgctg aaagcgtagt
    13141 aacaacgaat catgagaagt cagccgaacc catagtagtg aggaaacttc cgtaatggaa
    13201 gtggagcgaa ggggtgaata ctcaaacagt ctggggagag actgtttgag gtctgtcgct
    13261 agaaagagaa aacgacagat tgaagtaatc ctacttcact tgtgtctgta aaatgagtgg
    13321 tctgatagaa ctggactttg acacgtactg actagatgaa ggttcaccaa tataagatgt
    13381 ccctcaggca ccaaaacaag aaaggaatac gcacatgtca aaactgctag ataagatatt
    13441 atcacgcgaa aatatgctgg aagcctacaa tcaagtaaaa tccaataaag gctcagctgg
    13501 gattgatgga atgactatcg aagagatgga taattatttc agacaaaact ggcgcttgac
    13561 taaggaactg ataaaacaga gaaaatataa gcctcaacca gttcttaaag ttgagatacc
    13621 taaaccagac ggaggcatcc gtcaactagg aattccaaca gttatggata gaatgattca
    13681 acaggccatt gtccaagtca tgagccccat ttgtgaaccc tatttctcag atacgagtta
    13741 tggtttcaga ccaaataggt catgcgaaaa agccatcatg aagctcttag aatacttaaa
    13801 tgacggctat gagtggatag tggatataga cctagagaaa tttttcgata cagttcctca
    13861 agatagattg atgtccttag tacataacat tatcgaagac ggagatacgg aatccttgat
    13921 tcgtaagtat cttcattcag gtgttatcat taatggtcaa cgttataaaa cactagttgg
    13981 tacaccacag ggaggaaatt tatctcctct cttatccaat atcatgctta atgaattgga
    14041 caaggaatta gaaaagaggg gacttcgatt tgtgcgctac gcagatgatt gtgtgattac
    14101 ggtcggaagc gaggcagccg ctaagcgtgt gatgtattca gtcagtcgtt ttattgagaa
    14161 acggctaggt ttgaaagtaa acatgaccaa gactaagatt accagaccaa gagagttgaa
    14221 atatctaggt tttgggttct ggaaatcatc agatggttgg aaaagccgtc cacatcaaga
    14281 tagtgttcgg agatttaagc ttaaattgaa gaaactaaca cagaggaaat ggagtataga
    14341 tctaacaaga cgtattgagc aactgaattt gtctattcga ggatggataa actatttctc
    14401 attgggaaat atgaaaagta tagtcgccag catagatgag cgcttgcgta ctcgcctacg
    14461 agtgattatc tggaagcaat ggaagaagaa atcgagacga ttatggggat ttcttaagtt
    14521 aggagttcct aaatggatag cagataaggt atctggctgg ggcgaccatt atcaattagt
    14581 agctcagaag tcggtactta aacgtgctat atcaaaacca gtccttgaaa aacgtggact
    14641 ggtttcgtgt ttggattatt accttgaacg acatgcgtta aaagttagtt gaaccgccgt
    14701 atgccgaacg gcacgtacgg tggtgtgaga ggggctagag attatcccct actcgattaa
    14761 ctcccctgaa atttatttta attatgcaaa tttcacgtat ttttgatgct gagacgacga
    14821 tcctgggaac ttttcagata tttttttgac tatctaaatc tatcattaga aaagcttaga
    14881 gcgccaaagg atttgagcgt ttttctgatt tttaagactt tttccagtct ctttttcgat
    14941 tgaagatgta attattctac taactaacta acttcttagt actagccaac aacgataatc
    15001 ataattcctc ctaaaattag gaataataaa ggcaatagtt tttgtttttt catgtaaaaa
    15061 acctcacttt tgttttctgc tattttatgc taaaatatta aaaatcaaat ttaattccaa
    15121 agtttgtaac taaaggggga gcgctacatg tctaattcat ttgtcaagtt gttagtctct
    15181 caattatttg caaatttagc agatattttc tttagagtaa caatcattgc taacatatac
    15241 attatttcaa aatcagtaat tgccacatca ctagttccta tcttaatagg aatatcctct
    15301 tttgttgcga gtcttttagt tccgttggtt actaaaaggt tagcgctaaa tagggtttta
    15361 tctttatctc aatttggaaa gactatatta ttggcgatac tggtaggaat gtttaccgta
    15421 atgcaatccg tagcgccttt ggtgacctat ctatttgttg ttgcaatttc catactagat
    15481 ggttttgcag cacccgtttc ctatgctatt gtgccacgct atgcgaccga tttgggtaag
    15541 gctaattcag ccttatcaat gactggtgaa gctgttcaat tgataggttg gggattaggt
    15601 ggactcttgt ttgcaacaat tggtctgtta cctaccacgt ttatcatttt agtcttgtat
    15661 atcatttcta gctttctgat gttatttctt cctaacgctg aagtggaggt gttagagtca
    15721 gaaactaatc ttgaaatttt gctcaaaggt tggaagttag ttgctagaaa tcctagatta
    15781 agactttttg tatcagcaaa tttattggaa attttttcaa atacgatttg ggtttcttcc
    15841 attatacttg tttttgtaac ggagttatta aataaaacgg aaagttactg gggatattct
    15901 aatacagcat actctattgg tattataatt agtggcttaa ttgcttttag gctatctgaa
    15961 aagttccttg ctgctaaatg ggaaagtatt ctttttcctc ttgtagctat ggcaatagtg
    16021 acactgacta ttctatattt tccaaacgca cagatgtttt tattattttc agctttagtt
    16081 ggtatgttat cgcaactaaa agaagttcct gaaagtgtat ttcttcagga aacagtagag
    16141 gaaaatcatt tagttaatgt ctattccgtt cttgaagtga tttctacatt agcattttca
    16201 gtatttgttt tgctaatgag ctatattact gagagttttg gtattagcat cagtttttgg
    16261 ctatcagcca tttgtctgat gatagaagct attttaattt atatcagacg agattatttt
    16321 aaatgagaga gtggttaaaa agtctttaaa aatcagaaaa gcgcatagta tcaggtgttg
    16381 aaaaaacttg atattgtgtg ttttattatg ggaagattta cttcattgtc tcctgaaatg
    16441 gagttttgaa gcaggatcac tctatttgaa aatatacata gaaaaaccgc ataatcctta
    16501 aaataagctg aaatctattg gaaacatacg gtaaacaatt gaaaagatac tatataaagt
    16561 ggtacaatgg tagaaaaata agctagtaag aatcactctt attttagcga aaaattacag
    16621 aaatgaatgg tttttcttga tgaaacagag aaaagaattg tacctctttc ttggtcggac
    16681 agccttgtat tttcttatct ttctagggct gctttacttc tttagctatc ttggtcaggg
    16741 tcaaggaagc tttatctata atgaatttta acttgaagga gaatccctat tgtgtcaaat
    16801 aaaccaatag cagatatgat tgaaaccatt gagcattttg ctcagacaca gcctagctat
    16861 cctgtctata atgttttggg gcaggaacac acttatggcg atttaaaggc tgattcggat
    16921 agtttagctg cagtcattga ccaactaggc ttgcctgaga agtctcctgt ggttgttttt
    16981 ggtggccaag aatatgaaat gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc
    17041 tacattccaa ttgatagcca ttcggccttg gagcgagttt cagctatttt agaagtagca
    17101 gagccaagct tgattattgc catttcagcc tttcccttgg agcaggtttc tacaccaatg
    17161 ataaatctag ctcaggttca agaagccttt gcccaaggga acaactatga aatcacgcat
    17221 ccagtcaagg gagatgataa ttactacatt atctttactt ctggtacgac tggtaagcct
    17281 aagggagtgc agatttcaca tgataatctc ctcagcttta caaactggat gattacggat
    17341 aaggaatttg cgacaccgag tcgtccgcaa atgctggcac agccacctta ttcttttgac
    17401 ttgtctgtca tgtattgggc accgaccttg gcacttggtg gtacgctttt cactcttcct
    17461 tcagtcatca ctcaggactt taagcaactc tttgcggcta tcttttcatt gccaatcgct
    17521 atctggacat caacaccatc ctttgcagat atggccatgt tatctgaata cttcaacagt
    17581 gagaaaatgc ctggaatcac gcatttctac tttgatggtg aagaattgac ggtcaaaaca
    17641 gctcaaaaac tgcgcgagcg tttcccaaat gcccgtatca tcaatgctta cggcccaaca
    17701 gaagcgacag tagctctgtc agcagttgcc gtgacagacg agatgttagc gactctcaaa
    17761 cgcctaccaa tcggctatac caaggctgat tctccaacct ttatcattga cgaggaagga
    17821 aataaactgc caaatggcga acagggagaa atcattgttt ctgggccagc tgtttcaaaa
    17881 ggttatatga aaaatcctga aaaaacagca gaagccttct ttgagtttga aggtctgcca
    17941 gcctatcaca caggcgatgt gggaaccatg acagatgagg gcttgcttct ctacggcgga
    18001 cgcatggact tccagattaa gtttaacggt taccgcattg agttagaaga tgtctctcaa
    18061 aacctcaaca agtctcgctt tatcgaatct gctgtcgcag taccgcgcta taacaaggac
    18121 cacaaggtac aaaatctatt ggcttatgtc atcttaaaag acggtgttcg tgagcagttt
    18181 gagcgagata tcgatattac caaggccatc aaggaagacc tgacagacat catgatgtcc
    18241 tatatgatgc catctaaatt cctttaccga gacagtttgc cactaactcc aaatggaaag
    18301 attgacatca aaggattgat taacgaggtg aataagagat gatggagttt tttcaacagc
    18361 ttcctcattt agagccatat ggcaatcctc agtattttgt ttatgtgatt gctgcaacct
    18421 tgcccatctt tataggtctc tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa
    18481 gtctcttctt tattgtcacc atgttggtgg gtggaaagac caatcaacta gctgccttgg
    18541 gtatttacct ttgctgggaa atattgctcc tgcttttcta caagcattat cgaaaaagca
    18601 aggatggcaa gtgggtcttc tacttagtta gttttctgtc cctacttccg attatctttg
    18661 tcaaggtgca accagctatc aatggaacgc agtctttgct tgggttcttg ggaatttctt
    18721 acctgacctt tcgttcggtt gggattatca tcgagctgag agatggagtg attaaggatt
    18781 ttaccctctg ggaattcctc cgtttccttc tcttcatgcc aactttctcg agtggtccaa
    18841 tcgatcgctt taagcgattt aatgaaaatt atcaggccat tcctgagcga gatgagttga
    18901 tggatatgct ggatgaatct gtccgctata tcatgcgggg ctttttgtat aagtttatcc
    18961 tagctcatgt tttaggagag accttactcc ctcctctgaa gaatttagcc ttgcagtcag
    19021 gtggcttctt taatctctat gccttggcag ttatgtatac ttttggtctg gagctcttct
    19081 ttgactttgc aggttattct atgtttgctt tggccatctc aaacttgatg ggaatccgta
    19141 gccctatcaa ctttaacaag ccctttttat caagggattt aaaggagttt tggaatcgct
    19201 ggcatatgag tctgtccttc tggttccgtg actttgtctt tatgcgaatg gtgatggtgt
    19261 taaccagaaa gaaagtcttt aaaaatcgta atgtaacctc aagcatggcc tacattgtaa
    19321 atatgctgat tatgggattt tggcatggcg tgacctggta ctatatcgcc tatggactct
    19381 ttcatggact aggcttggtc atcaatgatg cctgggttcg caagaaaaaa acgctcaata
    19441 aggaacggaa aaaagcgggg aaggctgccc tacctgagaa tcgctggatt cagtttcttg
    19501 gcatggttgt cactttccat gttgtcatgt tgtcattctt aatcttttct ggattcttga
    19561 ataatctatg gtttaaaaaa taaaaggaaa taaaatatgg atatcaaatc agaagttatt
    19621 gaaattattg atgagttgtt tatggaagat gtttctgaca tgatggatga agatcttttt
    19681 gatgcaggtg tcttggatag tatgggaacg gttgagttga ttgtggagat tgagaaccgt
    19741 tttgacattc gtgtccctgt aacagagttt ggtcgtgacg actggaatac agctaataaa
    19801 atcatagctg gtattgtgga gctacaaaat gcttaaacgc ttatggatga tcttcggacc
    19861 ggtcttgatc gctggtttgt tggtttttct gctcattttc ttttatccta ctgagatgca
    19921 tcataatcta ggagctgaaa agcgttcagc agtggctact actatcgata gttttaagga
    19981 gcgaagtcaa aaagtcagag cactatctga tccaaatgtg cgttttgttc ccttctttgg
    20041 ctctagtgaa tggcttcgtt ttgacggtgc tcatcctgcg gtattagctg agaaatacaa
    20101 tcgttcctac cgtccttatc ttttaggaca ggggggagct gcatcgctta accaatattt
    20161 tggaatgcaa cagatgttac cacagctgga gaataaacaa gttgtgtatg ttatctcacc
    20221 tcagtggttc agtaaaaatg gctatgatcc agcagccttc cagcagtatt ttaatggaga
    20281 ccagttgact agttttctga aacatcaatc tggggatcag gctagtcaat atgcagcgac
    20341 tcgcttactg caacagttcc caaacgtagc tatgaaggac ctggttcaga agttggcaag
    20401 taaagaagaa ttgtcgacag cagacaatga aatgattgaa ttattggctc gttttaatga
    20461 acgccaagcc tccttttttg gtcagttttc ggttagaggc tatgttaact acgataagca
    20521 tgtagctaag tatttaaaaa tcttgccaga ccagttttct tatcaagcaa tagaagatgt
    20581 tgtcaaagca gatgctgaaa aaaatacttc caataatgag atgggaatgg aaaattattt
    20641 ctataatgag cagatcaaga aggatttgaa gaaattaaag gattctcaga aaagctttac
    20701 ctatctcaag tcgccagagt ataatgactt gcagttggtt ttaacacagt tttctaaatc
    20761 taaggtaaac ccgattttta tcattccacc tgttaataaa aaatggatgg actatgctgg
    20821 tctacgagag gatatgtacc aacaaacggt gcagaagatt cgctaccagt tagaaagtca
    20881 aggttttacc aatatagcag atttttctaa ggacggcggg gagcctttct ttatgaagga
    20941 caccattcac cttggttggt tgggttggtt ggcttttgac aaggcagttg atcctttcct
    21001 atccaatccc acaccagctc cgacttacca tctgaatgag cgctttttca gcaaagattg
    21061 ggcgacttat gatggagatg tcaaagaatt tcaatagata atataatata gaagagttca
    21121 agaatgaaac tagttttcac gttttttctt gactcttttt ttgcttgtga tataattaac
    21181 tggtaaacaa aatgtcaaag aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa
    21241 aggagtcaga tatgagacag ctagcaaagg atatcaatgc ttttttgaat gaggtgattt
    21301 tgcaggcgga aaatcagcat gaaatcctaa taggtcattg cactagcgag gtggccctga
    21361 ccaatactca ggagcatatc cttatgctct tgtcagagga atctttaaca aattcagaat
    21421 tggcccgtcg tctcaatgtc agtcaggcgg cagttaccaa ggccattaag tctttggtca
    21481 aggaagggat gttggaaaca tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt
    21541 tgactgactt ggctcgtcca atcgctgagg agcaccacca tcaccatgag catacacttt
    21601 taacctatga acaagtggcg actcagttta ctccaaatga acaaaaagtg attcagcggt
    21661 ttttgactgc tttagtagga gaaatcaaat aatgagatat attacggtag aggatttgtc
    21721 cttctattat gataaggagc ctgttcttga acatatcaat tatagtgttg atagtgggga
    21781 atttgttacc ttgactgggg aaaatggagc ggctaagacg acgctcatca aggctagtct
    21841 tggaattctg caaccacgca ttggaaaggt ggctatttca aagacaaata cgcaaggtaa
    21901 gaaattgaga atagcctatc ttcctcaaca aattgccagt tttaatgctg gttttccaag
    21961 tacggtctat gaatttgtca agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt
    22021 gaatgctcat gatgaggagc atatcaaggc cagtctggac tcagttggca tgtgggaaca
    22081 tcgagacaaa cgcttggggt ctctatctgg gggacaaaag cagcgagcgg tgattgcgcg
    22141 tatgtttgct tctgaccctg atgtgtttat cctagacgag ccgacaacgg ggatggatgc
    22201 aggaagtaaa aatgaatttt acgaactcat gcaccacaac gcccatcatc atggcaaggc
    22261 tgttttgatg attacccatg accctgaaga agttaaggat tatgcggatc gcaatattca
    22321 tctagtccgt aaccaagact cgccatggcg ttgtttcaat gttcatgaga atggccagga
    22381 ggtgggccat gcttagttta ttatcttacg actttataca acgcgccttt ttggcggtta
    22441 ttgctatgag tcttttctca ccggtattgg gaaccttcct catcttgcgt cgtcagagtt
    22501 tgatgagtga tacccttagc cacgtctcac tttcaggtgt agcctttggt ctggttttgg
    22561 ggatttctcc aactgtttct actattgcca ttgtcttgat tgcggcggtc tttctggagt
    22621 atctccgtac ggtttacaag agctttatgg aaatcgggac agctatcctc atgtcaacag
    22681 gtctggctgt ttctctgatt gtcatgagca agggtaaaag ctcgagttca atgagtttgg
    22741 accaatatct ctttggttcg atcgtgacta tcagtgaaga acaggtcatt tccctctttg
    22801 tcattgcggc ggttgttttg attttgacct ttctctttct tcgtcctatg tatatcttaa
    22861 cttttgacga agatacggcc tttgtggatg gcttgccagt tcgtaccatg tccattcttt
    22921 ttaacatggt gacaggggtg gctattgccc ttatgattcc tgcagcagga gctcttctgg
    22981 tatcgaccat tatggtcttg ccagctagta ttgccctgcg tctggggaaa aactttaaat
    23041 cggttatgct gcttgccagt gcgattggct ttttgggaat ggtagcagga ctttacattt
    23101 cctactatgc agaaacacct gcaagtgcaa gtattaccat tatttttgta actgtcttta
    23161 tactaatcag tttagtaaga cgttttatca aataggagac gaacgtgaaa aaaattagct
    23221 tattactagc cagtctatgt gccttgtttt tagtggcttg ttccaatcaa aaacaggcag
    23281 atggtaaact caatatcgtg acaacctttt accctgtcta tgaatttacc aagcaagtcg
    23341 caggagatac ggctaatgta gaactcctaa tcggtgctgg gacagaacct catgaatacg
    23401 aaccatctgc caaggcagtt gccaaaatcc aagatgcaga taccttcgtt tatgaaaatg
    23461 aaaacatgga aacatgggta cctaaattgc tagatacctt ggataagaaa aaagtgaaaa
    23521 ccatcaaggc gacaggcgat atgttgctct tgccaggtgg cgaggaagaa gagggagacc
    23581 atgaccatgg agaagaaggt catcaccatg agtttgaccc ccatgtttgg ttatcaccag
    23641 ttcgtgccat taaactagta gagcacatcc gcgacagctt gtcagcagat tatcctgata
    23701 aaaaagagac ctttgagaag aatgcagctg cctatatcga aaaattgcaa gccttggata
    23761 aggcttacgc agaaggcttg tctcaagcaa aacaaaagag ctttgtgact caacacgcag
    23821 cctttaacta tcttgccttg gactatggac tcaaacaagt cgcaatctca ggactttctc
    23881 cagatgcaga gccatcagct gctcgcttgg cagaattgac agagtatgtc aagaaaaata
    23941 aaatcgccta tatctatttt gaagaaaatg cctcacaagc ccttgctaac acactttcaa
    24001 aagaagcagg tgtcaaaact gatgtcctca atcctttaga aagtctgaca gaagaggaca
    24061 ccaaggctgg agaaaactac atttccgtga tggagaaaaa cctcaaggct ttgaaacaaa
    24121 caacagacca agaaggccca gcaatcgaac ctgaaaaggc agaggatacc aagacagtcc
    24181 aaaatggtta cttcgaggat gcagctgtca aggaccgcac cttgagtgac tatgcaggta
    24241 actggcaatc agtttatcct ttccttgaag acggcacgtt tgaccaagtc tttgactaca
    24301 aggctaagtt gactggtaag atgacccagg ctgagtacaa ggcttactat acaaaaggct
    24361 atcagacaga tgtgactaag attaacatta ctgataatac tatggaattt gttcaaggtg
    24421 gacaaagcaa gaaatacact tacaagtatg tcggtaagaa aattttgact tacaagaaag
    24481 gcaatcgtgg cgtgcgtttc ctctttgaag ccacagatgc tgacgctgga caattcaaat
    24541 atgttcagtt tagtgaccac aatgttgccc cagttaaggc agaacatttc catatctttt
    24601 ttggaggtac aagccaagaa gctctatttg aagaaatgga taattggcca acctactacc
    24661 cagataacct atctggccaa gaaatcgccc aagaaatgtt ggcgcattga tgagaaatcg
    24721 actagttcat aagagctagt cggttttttg atactagatg gctaacttca ttatagacct
    24781 ttcagaacta agggaacctg aaaaaataaa taaaactctt gaaatatctg gacttatatg
    24841 ctagaatgta gttagtgtat aaggttcatt agaacaccaa agcccctaac tagtgccata
    24901 gttaagggct tttttgacgt atcttagcga tttaatgggt gtttataggc tagtcagtcg
    24961 gtctacttct taccatctag ccatttgcag acgaaataca agataattcc agctataaca
    25021 tctgctataa tagtaagagc aagctctggt ataaggctca ttagtttcac ctcctctcac
    25081 gaacccatag gaacgtaatc ggtaaccgat gacaaaaata gtataccaca ctaaatttag
    25141 atcatcaacc tcacttaata cttgaactat tgtagattat atgctaaaat gtagttaatt
    25201 gataaggttc attagaacac caaagcccct aactatggcc gtagttaagg gcttttttga
    25261 cgtatcttag cgatttaacg ggtgtttata ggctagtcac tcggtctact ccttactatc
    25321 tagccatctg cagacgaaat acaagataat tccagctata acatccgcta taatagtaag
    25381 agcgagctct atgataaggc tcattagttt cacctcctct cacgaaccca taggaacgta
    25441 atcggtaacc gatgacaaaa atagtatacc acaatacatt tagatcatca aggtcactta
    25501 attcttgaaa tatagggtct aggcgacaaa gtctttaaaa tcagaaaaac gcataatatc
    25561 aggtgtgcaa aaacttgata ctatgcgttt tattgtggga aggtttactc cattttctcc
    25621 tgaaattgag tttttgtcca gcctctgttt ttagaattgc taagaaaata atgtcatgtg
    25681 gtgaatattt gtaaatcagt cagcagacag aacgaatact cttcgaaaat ctcttcacat
    25741 catgtcagct tcgtcttgcc gtgtccatgg gggacttgac ttcatcagtt ttcaaatctg
    25801 tactttgagc aagctgagac tagcttccta tttgattttc attgaatatc agaaacccat
    25861 tctccatcaa ataattcgac tgcatctaat aatttttggt ctggcaaggt gtcagaaata
    25921 aaggttgtgt atttggatag gggattaatt ttaaaaaatc cagtcttgta aaatttagaa
    25981 ctatcaatca gtaagatggt ttcatgggct ttgtcaataa tattcttttt tgaaatagct
    26041 tggctgagag aagcttcata aacatattgg tcatcaatac ctcttgctga acaaaatgct
    26101 aaatcgatat taaaatgatc taataaagaa ttttccttat catagttgac cacggaacag
    26161 gattgatgtt tgacctcgcc agatgtgata aagattttgg agctatcttt aacagtttca
    26221 gatagggttt gtgcagtatg taaaccattt gtaaaaataa tcaaattatc aagttcagaa
    26281 agatagggac agagttcgta gacagtcgta ctggaatcaa gataaataca catgcctgac
    26341 cgaataaagt ctttagcgag actagcgatt agtctttttt gcctagtact ttctccttcc
    26401 cgtatttgat gagaaagttc aattgtgttc atagaggaca gggtcacgta tccgtgcttt
    26461 cttttgataa gaccttgatt ttctaagaaa attaaatcac gacgtaaggt acttgtgctg
    26521 gagaaagtga tttctgccag ctcttttacg gcaattcttt ttttcttttt aataatttca
    26581 atcaattcaa gtacacgttc atcttttatc ataagctcct cctaatttat catttcaact
    26641 atattatagc acaaattgga ggaatttgaa ttatttttat gaatattggg ttaatatttg
    26701 aacattattc aagtaagcgt tcacatattg aaaaaataaa acgtggggat tataataaag
    26761 ttaatcaagg acgaagagag aagaaaaatg gaagcggttt tagcaataga tttaggtgcg
    26821 acttctggaa gagcaatcgt tggttacctt tctgaaaata aactagtaat ggaagaaata
    26881 aatcgctttt ctaatctacc tattagagta aaagggcatt tatcttggga tattgacttt
    26941 ctactagcta aaattcttga aagtatccgc ttggctaata ctagttacaa gattttatct
    27001 atcggtattg acacatgggg agttgatttt ggactgattg ataatgaagg taagctgtta
    27061 ttacaacctg ttcattatcg tgatgaaaga acaaagggag tgttaaagga aatatctgaa
    27121 atgactgaat tagaaaaact gtattcagag acaggaaatc agattatgga gataaatacc
    27181 ttgtttcaac tctttaaggc acgtcaagaa tctcctgact ctttctataa gaccaataag
    27241 attcttttaa tgccagattt gtttaattat ctcttgacag gtaagtttgc tacagaaaaa
    27301 agcattgctt caacaactca attatttgat cctaggagtc aaaactggaa tcagaatatc
    27361 ttaaaactat ttgaattgga ttcatcttta cttcctgaga ttgtttcaga gggaaatgtt
    27421 cttggaagga taaaaaagga gtatggttta ggcgatattc ctgttgtgaa tgtttgtagt
    27481 catgatacag caagcgcgat tgtctcagta cctaagacag aaggtagttt atttatttca
    27541 tcaggtactt ggtctttggt tggagtggaa cttacttcac cgcttcttac taccgaatcc
    27601 ttcagttatg gatttacaaa tgaagtcggt aaagatggag tgattacatt tctgaagaat
    27661 tgtacagggt tgtggatcat agaggaacta agacgttcat ttgaacgaag agggaaagcc
    27721 tattcttttg atgatattag gacaatggtg gagaaagaaa aagaaaatct tcctctgatt
    27781 gatactgaat caactgaatt tgcaacagaa tctgatatgc acaagacttt gacagaatat
    27841 ctagcttatc atcatgaaac tagagagtgg acagatggac aactatttaa gattgtttat
    27901 gaaagcctag ctgaaacgta taggaaagcg atagagttac tagaagaact aactcataag
    27961 gtttataaga ggatatatgt gattggagga ggtgctagag ccagttactt taaccaaatg
    28021 attgctgata gaactggtaa agaggttctt acaggtttga ctgagggtac agctgtgggg
    28081 aatattgttg tgcagctatt gagtcaaggt aaaataaacg aggatacaga gttaaaggat
    28141 attatgacaa atattgctga gacacaatat tattatcctc agctatcata aacaaaaata
    28201 aaaaaacgga ggttttgtca tgaacaaaaa aagtcttttg aaatgcgctg ttatcgggtt
    28261 agtagctacc tttggtttag cagcttgtgg aacatctaag gatgcaagcg gtggaagttc
    28321 ttctggtaaa gaagtattag aattttatca tgggtatcat catagtgaag atgaatggcc
    28381 tgtagcgaag actatgcgag atttatatga taaatttgca gaagaacata aagatagtgg
    28441 tgtagaattt aaaccaactc ctgtaaatgg tgatttgaag gatataatga ataacaaggt
    28501 tgctagtggt gaatttcctg atgtgattga cctagcaggt aatgcagtat cattagttgc
    28561 gattgaacaa aaacttgttt tagatttgaa accatatatc gattcaaata agcttgaaaa
    28621 aaatgttggt ttgaactata agcaaaacca aaaagatgga aaaatttata cagttcacga
    28681 acagttattt acaatgggtt tgtggtacaa caaggacata tttgcaaaag cgggtgctaa
    28741 gacacctgat cagtggaata cttgggatga tttcactcag gcaatggcaa gcattagaaa
    28801 acaagatgga gtgtatgcat ttggtgctgg agaaccatct attcgcttgt ttaatacagt
    28861 attaggaacc acagaaaatg gacgtaaatt attagataaa ccattaacaa aagaaggaat
    28921 tgaatctaaa gaatttgcag atgctttgaa aatggttatg aaagaaattc aagctaatgg
    28981 ttctaagaat gctggtggcg atgccaatgc ttattccaaa gatttccaag aaggtaaatc
    29041 tgcagtattc tttaatggtg tgtgggcttc tggtgagatg tctaagaacc caagtcttgc
    29101 acctggaatc tatcctgcag gtgtagcaat tagttcttct ggaggtggta tcactatctc
    29161 aagtaagatg tctgaagcta aacaaaaact agctcttgag tttttgaaat atatgactag
    29221 cgatgatgta caaaaagtaa tttttgaaaa agtaggagca aatccttcta atgaaaatgt
    29281 aaatgtaaaa gaactttcag aaaagagttc agaagctact actaaaattt taggacaagc
    29341 aatcactcaa gttaagaatg caaaagcagt tgttccaact gtaagtgatg tttggggtgg
    29401 cgatgtacag acagctatta tcaatgcatt gacagaaagt gctgctgaaa atgtagatgt
    29461 tgatcaaaaa gtaaaatcta ctcaagatgt gttgaaatca ttgattggtt aattgtttta
    29521 gggagtgaaa acgaagctca gttggcactg ccaactgagc ttgattttac ttatatagtt
    29581 gaaaaaagga gtttgtttat ggcacaaaaa attatgagcc tacaaaatag gaagaatcaa
    29641 aaaagacgat ttatcttttt atttcttttg ccaacgttga tttgtttctt tctattttat
    29701 ttttattctg tagtaacaat ctttttaact tcatttgcta aatgggatta tacaaattta
    29761 aacacccctg agtttcttgg atttgataaa ttatttgaaa attataggta tgtttttaaa
    29821 gaatacccat tttttacaga agctctaatt aattctgttc gttgggctgt aattggtgtt
    29881 attattcaag ttcctttagc tgtatctgtt gcaattacat tatctaagaa attaaaaggc
    29941 tggaagatat ctaggaatct ttatattgta ccaagtatca tttctagtgc tgctatgggc
    30001 ttgatttttc ttcaaatcta taatccaaac tatggtgttg ttaaccaaat tattcatcta
    30061 tttaatccat cgtttaaaga ttcagtactg ttgactccag gattaaatat agtagctatg
    30121 actggcgctt atatcttctt tgcaggagca tcaaccatta tgattcttgg gcaaattttt
    30181 gctattccag aagaagttca agaagctgct attttagaca atattactgg ttggaggaaa
    30241 gagtggtata ttacgattcc gatgattaag gggacaatta aaactgtttc aattatggca
    30301 gcaacttcag ggtttttgct ctataacgaa gtattctttt tgacaaatgg tgctgcagga
    30361 acaaaaagta tcagttttgt tattcgagaa ttagcagtgg ctagctcacg aactcagtat
    30421 gctcgtgcaa atacaattgg agttatacaa attttaggtg gaatgttgat tatcttttgt
    30481 attaatattt tattcagaga aagaaaaaga ctgaaaggtg ggaaatgatt atgaatacac
    30541 atataaatgg tattagtaaa aaaggcaaag ttcttatata tggttatatg ctccttacca
    30601 ttttaatttc tattttccct attgcgtgga tttttttatc atcattaaaa gcagatccta
    30661 tgaaaaatcc aggtattagt ttaccgactg actttactct tgaaggctat ataaatgttt
    30721 ttacaaaact tcatgttttc acttactttt ggaatagctt taaagtagtg tctatatcag
    30781 ttattattag cattgttatg atctccatgt cttcatatgt tattgctagg atggaattta
    30841 gagggaagaa gttggtgact tctatgctgt attctactct atttattcca gcaacagcta
    30901 tgacttttcc agtttataga ttagtaaatg agttggggat ttataatacc ccagttgctc
    30961 taattctggt ctactcttgt agtggaattg ctatgagttt ctttattata aagaactatt
    31021 ttgaaattat tccaaaagaa ttggaggagg cagcagagat tgatggtgcg acatatgctc
    31081 aaactttttg gaaagtgatg ttaccaattg ctagaccagg aattttaaca gcagcagtac
    31141 ttgcctttat taataactgg aatgaatatt attgggcatc tatgttggtg attgataaaa
    31201 atgaattaac agtaccagca ttactaggtc aatttactac aagttttaat actaattata
    31261 atggtctatt ttcagctatt gttgtaatcg tattaccacc aatcattcta ttcgcattta
    31321 caagtaaata cttcattgaa gctttaggag gaggagcagt aaaaggatga aacatacact
    31381 tgaaactatc aatagtagaa ctcagtggtt tagagaagca agatttggga tgttcattca
    31441 ttgggggtta tattctattc caggaaaagg ggaatggatt cgtagtcatc agaaattatc
    31501 tattgaagat tatgaaccat attttcgagc ttttgatcct aaggaatata accctagaga
    31561 atgggctaaa caagcaaaag ctgcagggat gaagtatatg gttttaacgg ctaaacatca
    31621 tgatgggttt tgtttgtttg attcaaaatt tacagattat aaagcaacaa atacacctgc
    31681 aggtagagat ttagttaaag aatttgtaga tgctgttcga gctgaaggtt taaaagtagg
    31741 cttatatttt agtttgattg actggcacca tcctgatttc cctaaatatg ctgatctaaa
    31801 tcatccaatg agaggaaatg aagcctatcg agatgagaaa attaactttg acagttattt
    31861 ggagtattta cacaatcaag ttaaagaaat tgtaactggt tatggtcaga ttgacatatt
    31921 atggtttgat tattcttatg aagacatggt gggtgaaaaa tggggagctt caaaattaat
    31981 agacatggtt cgtcattatc agccaaacgt tatcgtagat aatagattag aaacatcagg
    32041 tgaaggattc ggaagtatcg ttacagatga aattacctct tacgctggag attttgttag
    32101 tccagagcaa attgttcctc acgaaggtat tcgaaacttt aaaggtgaac ctgttccttg
    32161 ggaactttgt ctaactatga ataacaattg ggcttataat cctacagatt atctatataa
    32221 gtctagtcaa actttgataa gaaagttagt ggaatgtgtt agtaaaaacg gaaatatgat
    32281 tcttaatgta ggcccagatg ctttgggaag aattaatgat tcaagtaaga aaatattaga
    32341 taattttcat cgatggatgt ctcgaaatgg tgaggcaatt tatggatgta gtggagatga
    32401 aaatttacca aaaccagatt ggggatacta tactcgtgat gaaaatacgg tttatgctca
    32461 tgtatttgaa caacctatag gtcctttagc tcttcttggt attagtaaag aaaacgtaaa
    32521 aagaatgagc tttcttcatg atggaagtga ggtgaaaatt tcagaaagct ggacgaccaa
    32581 tgcctacaaa ggaatttgtt ttgcacagtt tggagaagtt ccacatttta cctatccatt
    32641 accagacttg attgatagcg taatcaaaat tgagttgaga gagtagttta tatgaaaatt
    32701 gaaaataaaa atgtaagacg taatttcttt tggggagatg gtcgatttta tactactgat
    32761 atcgtaaaca aacgggcagg agtaatgata aaaaatgttt cgaaagaaga atttaccatt
    32821 acattggaga atggtataag actttcttca aatcattttt cagcaatcgt tagggaagag
    32881 ggagatacgc gaattcaggt ttcttttgtt tgtccttcca ttcgtttacg tttaatcttt
    32941 gaatcgaggg atgatgttct ttcgaagcaa ttagttttag aatcatctac tgaggttatt
    33001 aaatctgtag aggtagagag ttttgagttt gaaacagaag acaatatttt ctatccgaaa
    33061 agacaagatt gtattaagga aatggcgaat ttttccggtt attatgtaga attgggacaa
    33121 cctgtttatg cgaattcttt attcttagga atggaatttc caatgtctga aaacaaggta
    33181 gatggtagac actatgtatc aagatattac ttgggaactg ttgtaaatca agaaaagagt
    33241 ttgtggtctt gtattattgg gggagcatgt tcttataaaa aagaagagat tcaagaggca
    33301 ttttttgaat atgttgaagg aatagctcaa cctagttatt tccgtaaaca gtataattcc
    33361 tggtatgacc atatgaccga tattacagag gaaggtattt taaaaagttt ttctgagatt
    33421 cgagatggat ttgaaaatca tggagttcat ttagatgctt atgttgttga tgatggttgg
    33481 acaaactatc aatcagtttg ggaattcaat cataaattcc caaatggttt gagaaatatt
    33541 aaacatcttg taaatggatt tggttcaagc ctaggattgt ggattggtcc ccgaggtggt
    33601 tataatggga cagaaatcat tatgagtgat tggttagaag cacatccaga gttaaatatt
    33661 ggatctaaaa atttgatttc aaatgatgta aacgtggctg attttaacta tctcaatcaa
    33721 atgaagaaaa agatgttgga atatcaaaaa gaattcgata tcagctattg gaaaattgat
    33781 ggttggttac ttcaacctga caaacctgat aagagtggac cgcacggtat gtataccatg
    33841 acagcggttt atgagttctt aattcaactg ttgatagatc taagaaagga gagaggagga
    33901 aaagattgtt ggttaaactt gacttcttat gtaaatccta gtccatggtt tttacagtgg
    33961 gtcaatagtt tatggattca aatatctcaa gatgtaggct ttacagagaa tgcaggtaat
    34021 gatatcaatc gtatgattac ttaccgagat agtcagtatc aagaattttt ggaaaaacgt
    34081 gagatacagt tacctatgtg gtcgctttat aatcatgaac caatctatgc tgtcagtgca
    34141 aatacctggt acatggatca tcaaatgttt gcatcaatac cagattttga agcttatcta
    34201 ttatttattt caacaagagg gaatgctttt tgggagtttc actattcttt tgatatgttt
    34261 gatgaagaac gctggaaagc caatgctcgt gccgtcaaat ggatagagga gaattatcaa
    34321 acactaaaat atagtaaaaa aataggagga agtcctgaaa aatttgaaat ttatggttat
    34381 aagtgtcaca atcagaagac ttctactgaa attctctctc tgagaaatcc tgctcagatt
    34441 aaacaaaaaa taaaaataga gaatctttcg atagagaatt ttaccagagt aattggagat
    34501 tttactattc aagaagatga gatagaattg gcaccgtact ctatcgtgat actgaagaag
    34561 taaagaaaaa attgtgaggt agagatgacg atttatatta ataaggacga gaccgttttt
    34621 catttggcaa tgaaagatag tagttatatt tttagaattt tagaaaatgg ggaacttcaa
    34681 catctacatt ttgggaaaag gattcatgtc aaggaaaatt ataaccaatt gatggcctat
    34741 gaaaaaagag gatttgaagt atctttttct gaagaatttg aggatattca acagtctatg
    34801 atacaaaatg aatattcttc atatgggaaa ggagattttc ggcatccagc ctttcaagtt
    34861 caaggaatga atggtagtag gataacgaca ctaaaatatc aaggttttga acttgaaaaa
    34921 gggaaaaatc gtcttaactc tctaccttca acatttgatg atattggtca gtgtgcggaa
    34981 acattaacga ttattttaac agattccata ttagatttaa ctgttagact aaattacaca
    35041 atttttccgg aatacaatgt cttagttaga aatacggaat ttttaaataa tagcaataat
    35101 aagttgactc ttttgaaagc aatgagctta cagctagatc tacctgatag tcaatatgac
    35161 tttattcaat tttctggagc atggctgagg gaacgtcagt tatatagaac ttcgcttaga
    35221 ccaggtattc aagcaataga tagcttgaga tactcatcaa gtcctcagca aaatcctttc
    35281 tttatgctat caaggaggga aactacagag catagtggtg aggtttatgg ttttaacttt
    35341 atctattctg gaaattttca aaatatgatt gaagttgacc attttgacac cgctagagta
    35401 acggtaggaa taaatccagt agaatttcgt tttttattaa atcctgccga aagttttgtg
    35461 acaccagaag caattgtgat ctattctgat caagggatga atcagatgag ccaacaacta
    35521 tcagattttt atcgacatca tttagttaat cctaattttt ctcaagctag tcgtcctata
    35581 atactcaata gttgggaaac attttatttt gacttgagta cagaaaaaat tttagattta
    35641 gcaaaggctg ctaaagattt agggatagaa ttatttgtac tggatgatgg ttggtttggt
    35701 cataggaaag atgacaaaag ttctctgggt gattgggtaa cagatagaag tcgccttcct
    35761 gaaggtattg gatttcttgc agatgaaatt cacaaaatag gtttacaatt tggtttgtgg
    35821 tttgagcctg aaatgatttc tattgatagt gatttgtaca agaatcatgc cgattggact
    35881 atccatttgt tagacagaga gaagtcagta ggaagaaatc aatatgtgtt ggatttgacg
    35941 agacaggaag ttgttgatta tctttttgat tctatttcta aaatcataat caaaacaaat
    36001 ctggattata tcaaatggga tatgaatcgt catataacag atatttatag tattgaactt
    36061 gattctgaac agcagatgga atttggtcat cgatatatct taggtcttta tcagttatta
    36121 gatcgtttaa taactaagtt cccttcagtt ctatttgaat cttgttcttc aggtggtgga
    36181 cgttttgatt taggacttat gtattatgca ccgcaagcgt ggacgagtga tgatacggac
    36241 ccgatagaaa gattgaaaat tcagcatgga acttcttatg gatattctcc atcaatgatg
    36301 acagcccatg tttctatttc tccaaatgaa caaagtggaa gacaaacgag tttggacact
    36361 aggacaaatg tagcttattt tagttctttc ggttatgaat tagatgttac gagattgtcg
    36421 gtagaagaaa aagaacaagt gagagaacaa attcagtttt ataaaaaata tcgttcattg
    36481 cttcaatatg gggatttcta taggataaac agtcctttta gttgtgattc tgctagttgg
    36541 caagttgttt caaaagataa atgccaatcg attttattgt atgctcaatt gaatagtaag
    36601 ttgaatccag gttatacaag agtttatttt agtggtttag ataaagataa atgctattcc
    36661 gtctctggat ttgatgagtt cttttatgga gatgaattaa tgaatgctgg aataaaagta
    36721 agtttaagta atttagcact ttgtgttcca gaatatctta caaaattatt tgttattgaa
    36781 gaagttgtat gtaaatattg aggaaataaa aatggaaagt aaaaaaatag caaaacagat
    36841 tttaatagct acggctgttt taacaagttt tttaggaagt aatttggttt atgcagatgt
    36901 agttcaaagt aattctaata acagagctag tactgaaact gctagagtaa cagggaataa
    36961 cttagaaaaa cttattatta aagataaaga aattgataaa gagatgacat atctttcaga
    37021 tatggattgg tcttctgcaa ctcatggtga tatagataaa acaaaaacag tacaaaaaga
    37081 tgctccattt acaacaggaa ataaaggaga gcatactaag atttcattgc tcacttctga
    37141 tgataaagtt aaatattttg ataaaggaat aggaacagtc gcagattctc catcagtaat
    37201 cagctatgat atcagcggtc aagggtttga aaaatttgaa acttatatag gaattgatca
    37261 aagtgctaat agttctagat cagaccatgc agtagtggat agaatagaaa tagaaattga
    37321 tggaaaggtt gtctattcta gtagtgtaac taatccagaa ggattcagat ataataccca
    37381 ggcacaattt attagtgtga caattccaca aaacgctaaa aaaatatcct taaaatcatt
    37441 cgcaggagaa catacatggg gtgatgaggt tgtatttgct gatgctaaac ttattaaaac
    37501 tgttagtact caaactataa ctccagatct tcttaataaa ggaattaatg gaggagtata
    37561 tctttctgat ttagaatggg ttgatgctac tcatggtgat gacgataaat caaaaacagt
    37621 tcagaaagat aaaccgttta cacctggtaa taacgggtct aataataaaa taaaattact
    37681 aattgacggt aaggaagtcg aatttaataa gggattggga actgtagcaa gtaacccgtc
    37741 tagtataaaa tatgatgttt cgggtgctaa tgttacaaga tttatttcct atgtcggaat
    37801 tgataggagt gcaaatcatt taaattcaga ttacgcagat attcaaaaat ttgaagttgt
    37861 tgcggatggt aaagtcattt actcatcaga ttcaaaatat ccaaaaggaa ttaagtatga
    37921 tacatcggca tttctggttg atgttgaaat tcccaaagat acacagacaa tagaacttaa
    37981 atcatattca gggaaacata catgggctga cgaattggtt ttaggtggag ccttgtttat
    38041 ggcaaatggt aaatttaaga atcctaatga ttggtcagaa gttgataaac gtcgtgaaat
    38101 taataatgaa catccgttac ttatgatgcc tttatatgct aacggagaag agtttaacca
    38161 agggaaatat actttttggg gaggagatac attaacaggt aagtgggaga atataccaga
    38221 tgacttaaaa ccatatactg ttatacagtt acatccagat gatcttccta aaagagatgg
    38281 agctgctaga gatttttatg agcatatgtt agaagaagca gcgaaatatg taaatcctaa
    38341 gactggaaaa aatgaaccta ttccagttat tctaacggtt tacactgctg gtaatatgcc
    38401 ttattatact tcggcacatt ggttaagtac cagctggatt gataaaatgt atcaaaaata
    38461 tccaaatttg catggtattt tcagtactga gaattattgg atttgggcaa atgatattga
    38521 aaataaggcg gcagattact taaaagtatc agctaaaaat ggaggatatt ttatatgggc
    38581 tgaacaaaat aatggttctg caatagaaaa agcatttgga aaaaacggta agatagcatt
    38641 tcagaaatct gttgataagt actggaagaa ccttattttc atgttcaaaa atacacctgc
    38701 tgctgaggga aatgattcaa ctacagaaag ttatatgaag ggactttggc tttcaaatca
    38761 tacttatcaa tggggtggtt tgatggatac ttggaagtgg tatgagacag gtaaatggaa
    38821 actgtttgca agtggtaata tcggaaaaag tcaaggagat agacaatggt tgactgaacc
    38881 agagtctatg ctaggagaag aagctttagg ggtttacctt aatggaggtg tagtttataa
    38941 ttttgaacac ccagcttata cctatggtgt aaataataaa gaaagcttac tctttagcga
    39001 agtaataaaa gaatttttta gatatgtaat agcgcatcca gcaccatcca aagaaaaggt
    39061 acttgaggat acaaaagtat tcatacatgg agactattca aataaaggaa atggtaagtt
    39121 ctttgtaaac gtaaatactg atagagaaca aactccatta tacatgactg gtcgttataa
    39181 tgttattcca gctattccag gtgttttaaa aacagataaa ttgaaagagt ctgtttctgg
    39241 tagccgtatt cagattaagg aaatcacttc tccagaattt agctctactc aggctagaaa
    39301 agaatactta aataagctgt atcctatgaa ttatgaagga gatatctttg ctcagaaatt
    39361 agataataga tggtttgtct ataattataa ggtaaatgag aatgttaaac agactgggaa
    39421 attaaaattt aattctttag aaatggatgt tgaatttgaa cctcatacct atggtatttt
    39481 tgagagaata agtaatggat tgaaagtgaa tttaaataat tttagaacaa ataaagattc
    39541 actatggtct aatgctcaag atgcaaatca ggcaaagaaa ctaccacaat tgaccaagaa
    39601 aggtgccatt aagtggattg aagaacatta tatcaaagat actcagtttg gagagaaaag
    39661 ggttacaaag atagtattaa gaggtataga taaacttcct actattcatt cattatcagg
    39721 aacaaatgat tcctatgatc agccatctct caattttgat cagaaaaatc atatggttaa
    39781 tattaccatt aacagtaacg gaaatcttga attcgaactt catttttaga aaggagtgag
    39841 tttatgtctc aagatgaaaa attaattcgt gaacagattt gtgatgtttg tcataagatg
    39901 tggcaacttg gttgggttgc tgctaacgat gggaatgtat ctgttcgatt agatgaggat
    39961 accattcttg caacacctac tggtatcagc aaaagtttta ttacaccaga aaagctggtg
    40021 aagttaaatc ttaaaggaga gattttagaa gcagaaggtg attactgtcc ttctagtgaa
    40081 attaaaatgc acattcggtg ctacgaagaa cgtgaggatg ttcgttcagt tgttcacgcg
    40141 catccaccga ttgcaacagg atttgctctt gcacacattc ctttagatac ttattcacta
    40201 attgagagcg cgattgtggt aggggcaatt cctataacgc catttggagt tccgtctaca
    40261 atggaagtgc cagaagcaat tacaccttat ctgcccgatc atgatgtcat gctattagaa
    40321 aatcatggag ctctgactgt cggaagcgat gtaattacag catactaccg tatggaaact
    40381 ttagaattag tcgcaaagac aaccttccac ggaagaatgt tactttctac aaagggcatt
    40441 gaggagcaag aaattgctcg tccgacttta gaacgtctat tctcaatgcg agaaaattat
    40501 aaggttacag gtcgtcaccc aggctaccgt aaatataatg gcgatggtag tatgaaagaa
    40561 acagaaaaat aagaggaaaa tagtatgatt caacatccac gtattggtat tcgtccgact
    40621 attgatggtc gtcgtcaagg tgtacgcgaa tcacttgaag tacaaacaat gaacatggct
    40681 aaaagtgtgg cagatttgat ttcaagcaca ttgaaatatc cagatgggga acctgtggaa
    40741 tgtgtgattt ctccatctac cattggtcgt gttccagagg ctgcagcttc ccatgagttg
    40801 tttaaaaaat caaatgtttg cgcaacaatt acagttacac catgctggtg ttatggtagt
    40861 gaaactatgg atatgtctcc agatattcct catgctattt ggggatttaa tgggacagaa
    40921 cgcccaggag ctgtctatct tgcagctgta ctagcttcac atgctcaaaa agggattcca
    40981 gcctttggga tttatggtag agatgttcag gaagctaatg atacagctat tccagaagat
    41041 gtcaaagaaa aacttttacg ttatgcgcgt gcagctcttg caactggctt gatgagagac
    41101 actgcttacc tatcaatggg tagtgtttcg atggggattg gtggttctat tgtaaatccg
    41161 gatttcttcc aagaatactt aggaatgcga aatgaatcgg tagatatgac ggagttcaca
    41221 cgccgtatgg acagtggtat ttacgaccct gaagagtttg aacgtgctat ggtttgggta
    41281 aaagaacata tcaaagaagg agttgaccga aatcgtgagg atttgattct ttctaaagaa
    41341 gagaaagaaa aacaatggga atttgttatt aagatgttca tgattggacg tgacttaatg
    41401 gttggtaacc caagacttgc tgaacttggt tttgaggaag aagcagttgg tcaccatgct
    41461 ttagtagctg gtttccaagg tcaacgtcag tggacagacc attttccaaa tggagatttt
    41521 atggaaactt tcctcaatac tcagtttgac tggaatggta ttcgaaaacc atttgtattt
    41581 gcgacagaga atgattcact aaatggtgtg tctatgctct ttaattatct attaacaaat
    41641 actccacaaa tctttgctga tgtgcgtact tattggagtc cagaggctgt tgaacgtgta
    41701 acaggacata ctttagaggg tcgtgctgca gctggcttct tacatctaat caactctgga
    41761 tcttgtacat tggatggtac aggtcaagct actcgagatg gcaaacctgt tatgaaacca
    41821 ttctgggagt tggaagaaag tgaagtgcag gctatgcttg aaaatacaga cttcccacca
    41881 gcaaaccgcg aatacttccg tggaggagga ttctcaactc gtttcttgac gaagggggat
    41941 atgccagtaa caatggtacg tctcaatctt ctaaaagggg ttggtccagt gctacaaatt
    42001 gcagaaggtt acacacttga acttcctgaa gatgttcacc atactttaga taatcgtaca
    42061 gatccaggat ggccaactac ttggtttgct ccacgtttga caggaaaagg tgctttcaag
    42121 tctgtctatg acgtcatgaa taattgggga gctaatcacg gagccataac atatggccac
    42181 attggagcag acttgattac cttggcttct atgttgagaa ttcctgtcaa tatgcataat
    42241 gtacctgagg aagatatctt tagacctaaa aattggtcct tatttggaac agaagatcta
    42301 gaatcagcag actatcgtgc atgtcagttg ttgggaccac tacataaata aaacttgttt
    42361 atataggagg tgaacttacg tccctcctat ccttttaaaa agatttgtta aacaattcac
    42421 aaataattga aaacgaatac aaaaagtaat ataatgatgt taaatagata gcgcggaggc
    42481 gcaggaggaa aattatatgg ctatatttta tgttccggca gtcaacctta ttggaaaagg
    42541 tgttgtaaat gaagtgggtc cttatatcaa ggaacttggc tataaaaagg cacttttggt
    42601 tacagataag tacatcgaag gcagtgatat tttacctaag gttttaaaac cactggatac
    42661 agaaggaatc gaatatgtca tctttagcga tgtagagcca aaccctactt gtaagaatgt
    42721 cacagatggg gtagctgctt tgcaagaaca tggctgtgat tttatcatca gtcttggcgg
    42781 gggttctcca caggatgcag ctagttgtat ttctatcatg gctacaaatg gtggaaaacc
    42841 acaggattat gaagggcttc ataagtctgc taaaaaaggc cttcctgttg tagctatcaa
    42901 tactacggca ggtacatcag cagaaattac cattaactat gtgattactg atgaagaacg
    42961 caaggttaag atggtaatgg ttgacaagaa tagccttgcc ttgatttctg tcaatgaccc
    43021 tgaactcatg ctttccaaac ctcaagcctt gactgctgct actggtatgg atgctctgac
    43081 tcacgctgtt gaagctttgg taacacctgg tgcttatgat gtaaccaaga aactgtctat
    43141 tggtgctatt gagcttatca aggaatatct tcctcgtgct gtagcaaacg gacatgatat
    43201 tgaagcgcgt gaaggtatgg tcaatgccat cttccttggt ggtatgagct ttaataatgc
    43261 tggtcttggc tatgttcact caatggctca ccaactcggt gcagtatata atttgccaca
    43321 tggtgtttgc tgtgccatgt tgctaccagt tatagaacgt gaaaatgcta aacgtgtacc
    43381 agaagctttc cgcaatgttg ccaaagcctt gggacttcat gtagaaggta aatcagatca
    43441 agaatgtgcc gattatgcga ttgctgagat tgagaagctt tctgagacag taggtattcc
    43501 taagaaactg actgaacttg gtattgaaga aaaagatttc gactttgaat acctttctaa
    43561 gaatgccttg attgatgcct gcgcaccagg aaatccattt atgccaacct tagaagaaac
    43621 gattgccttt tataaagagt tattttagca aggattagac gacaatagga caattcacct
    43681 ctaattattg acatttcagg aaaaatcgca gtaaaaacgg cacagccttc tttaaatgtg
    43741 ctataatact agaaaaatac ttgtggaggt tccattatgg caatattttt catgattttt
    43801 ctgattgttt gtgtgctcct attggtgata gtcacactga gtacagttta tgtggttcgt
    43861 cagcagtcgg tggcgattat tgaacgcttt gggaaatacc aaaaggttgc caatagcggt
    43921 attcatattc gcttgccttt tgggattgac tcgattgcag cacggattca gttgcgcttg
    43981 ttgcaaagtg atattgtggt tgagactaag accaaggaca atgtgttcgt tatgatgaat
    44041 gtagcgactc agtaccgtgt caacgagcag agcgtgacag atgcttacta taaactcata
    44101 cgtccagaat ctcagattaa atcttatatc gaagatgctc ttcgctcttc tgttccaaaa
    44161 ttaaccttgg atgaattgtt tgagaaaaaa gatgagattg cccttgaagt tcaacaccaa
    44221 gtagcagaag aaatgaccac ttacggctac attatcgtga aaaccttgat taccaaggtc
    44281 gaaccggatg cagaagttaa gcaatccatg aatgaaatca atgcggcgca acgtaagcgg
    44341 gtcgcagcac aagaattggc ggaagctgac aagattaaaa ttgtcactgc agctgaagcc
    44401 gaagcagaaa aagaccgcct tcatggtgtg gggattgccc aacaacgtaa ggcgattgtg
    44461 gatggattgg cagagtctat caccgaactc aaggaagcca atgttggcat gacagaagaa
    44521 caaatcatgt ctatcctctt gaccaaccag tatttggata ccttgaatac ctttgcctct
    44581 aaaggaaatc aaaccatctt tttaccaaat acgccaaatg gtgtggatga tatccgaaca
    44641 caaatcttgt cagcccttcg cgctgagaag aaataataga ctaatactct tcgaaaatct
    44701 cttcaaacca cgtcagcgtc gccttgccgt atatctgcaa cctcaaaaca gtgttttgag
    44761 ctgacttcgt cagtcttatc tacaacctca aaacggtgtt ttgagcaacc tgtggctagt
    44821 ttcctagttt actatttgat tttcattgag tacaaagagc ttggcaacag gctctttttg
    44881 tattgcgttt attaagaaaa acaaaaaaca tagatataca tttaactaaa aattattgta
    44941 tgttatctcc cttaattagg aatgataagg gaataactag aaagatttgt gaatacaaac
    45001 tatttctgat atacaaaata tacagtaata atgaatgatg ggagatggga tgaaagaatt
    45061 tcaatttgag agaaagcagc gtttttcttt gaggaaatat gcaataggag cttgttcggt
    45121 cttgctagga acgagtttat tttttgctgg tatgggtgct cagcctgtac aggatacaga
    45181 aacgagttca gcactaattt caagtcatta tttggatgag caggatttat ctgaaaagct
    45241 gaaatctgag ttgcaatggt ttgaattaga aaacaagctt ttgaacttat gggagcatta
    45301 ggttactatg aaggatttgt tccttatgtt tcaaatcaat acaaaaacca agctgaagaa
    45361 gaagacaaac cgctatctga taaatatatt ttcgaaaaaa tcttaggaaa aacatatgca
    45421 gccttcaaaa aagatcaaat taatgagcgt gtcgagaaat taggtaagtt aaaacctatt
    45481 acaataaatt acaacggaaa atcagaagta attgatagta aagaaaaatt acaagagctt
    45541 atgaataaag ccgttaaaga cgaagtggct caaatatagt aaaatgaaat aagaacagga
    45601 caaatcgatc aggacagtca aatcgatttc taaaaatgtt ttagaagtag aggtgtacta
    45661 ttctagtttc aatatactat aaaatcaggc aataccacgg ttaaaaagtt tgagtttatc
    45721 gaaacaccag tgcaaaaact gaaaaaagcg atttataaag ctcatctcaa agattcagat
//
LOCUS       DAVKZI010000012        44043 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKZI010000012 DAVKZI010000000
VERSION     DAVKZI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.012"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(60..218)
                     /locus_tag="VXB18_000783"
     CDS             complement(60..218)
                     /locus_tag="VXB18_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0382016.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(289..735)
                     /locus_tag="VXB18_000784"
                     /pseudo
     CDS             complement(289..735)
                     /locus_tag="VXB18_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(811..1401)
                     /locus_tag="VXB18_000785"
                     /pseudo
     CDS             complement(811..1401)
                     /locus_tag="VXB18_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1325..1519)
                     /locus_tag="VXB18_000786"
     CDS             complement(1325..1519)
                     /locus_tag="VXB18_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0382017.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1752..2039)
                     /gene="tnpB"
                     /locus_tag="VXB18_000787"
     CDS             complement(1752..2039)
                     /gene="tnpB"
                     /locus_tag="VXB18_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0382018.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWLSTEKDVKALAPEQVD"
     gene            complement(2020..2205)
                     /locus_tag="VXB18_000788"
     CDS             complement(2020..2205)
                     /locus_tag="VXB18_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382019.1"
                     /translation="MPQPIVPVEIPQSRLFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2509..4071)
                     /gene="guaA"
                     /locus_tag="VXB18_000789"
     CDS             complement(2509..4071)
                     /gene="guaA"
                     /locus_tag="VXB18_000789"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0382020.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4213..4911
                     /locus_tag="VXB18_000790"
     CDS             4213..4911
                     /locus_tag="VXB18_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0382021.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4954..5850)
                     /locus_tag="VXB18_000791"
     CDS             complement(4954..5850)
                     /locus_tag="VXB18_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0382022.1"
                     /translation="MSNSLKGTLLTVVAGIAWGVSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5859..6794)
                     /locus_tag="VXB18_000792"
     CDS             complement(5859..6794)
                     /locus_tag="VXB18_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0382023.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6791..7516)
                     /locus_tag="VXB18_000793"
     CDS             complement(6791..7516)
                     /locus_tag="VXB18_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0382024.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7600..8235)
                     /locus_tag="VXB18_000794"
     CDS             complement(7600..8235)
                     /locus_tag="VXB18_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0382025.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8237..9064)
                     /locus_tag="VXB18_000795"
     CDS             complement(8237..9064)
                     /locus_tag="VXB18_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0382026.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9086..10403)
                     /locus_tag="VXB18_000796"
                     /pseudo
     CDS             complement(9086..10403)
                     /locus_tag="VXB18_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189734.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10651..11262
                     /locus_tag="VXB18_000797"
     CDS             10651..11262
                     /locus_tag="VXB18_000797"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0382027.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11307..12035
                     /gene="rlmB"
                     /locus_tag="VXB18_000798"
     CDS             11307..12035
                     /gene="rlmB"
                     /locus_tag="VXB18_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0382028.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12074..12985)
                     /gene="trxB"
                     /locus_tag="VXB18_000799"
     CDS             complement(12074..12985)
                     /gene="trxB"
                     /locus_tag="VXB18_000799"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0382029.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELSEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLNPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13051..13275)
                     /locus_tag="VXB18_000800"
     CDS             complement(13051..13275)
                     /locus_tag="VXB18_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0382030.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13353..14096)
                     /locus_tag="VXB18_000801"
     CDS             complement(13353..14096)
                     /locus_tag="VXB18_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0382031.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14096..14896)
                     /locus_tag="VXB18_000802"
     CDS             complement(14096..14896)
                     /locus_tag="VXB18_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0382032.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15054..15410)
                     /locus_tag="VXB18_000803"
     CDS             complement(15054..15410)
                     /locus_tag="VXB18_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0382033.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15423..15935)
                     /locus_tag="VXB18_000804"
     CDS             complement(15423..15935)
                     /locus_tag="VXB18_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0382034.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15935..16429)
                     /locus_tag="VXB18_000805"
     CDS             complement(15935..16429)
                     /locus_tag="VXB18_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382035.1"
                     /translation="MEIRLAFPNEVGAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16564..17010
                     /locus_tag="VXB18_000806"
     CDS             16564..17010
                     /locus_tag="VXB18_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0382036.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGINPANPIIQTSCQTIKLYHQTLDLIDHTQEEVIQ"
     gene            17007..17654
                     /locus_tag="VXB18_000807"
     CDS             17007..17654
                     /locus_tag="VXB18_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0382037.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17675..18256)
                     /gene="pdxT"
                     /locus_tag="VXB18_000808"
     CDS             complement(17675..18256)
                     /gene="pdxT"
                     /locus_tag="VXB18_000808"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0382038.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18257..19132)
                     /gene="pdxS"
                     /locus_tag="VXB18_000809"
     CDS             complement(18257..19132)
                     /gene="pdxS"
                     /locus_tag="VXB18_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0382039.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19284..20663)
                     /locus_tag="VXB18_000810"
     CDS             complement(19284..20663)
                     /locus_tag="VXB18_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0382040.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20957..21880
                     /locus_tag="VXB18_000811"
     CDS             20957..21880
                     /locus_tag="VXB18_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0382041.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21940..22545
                     /locus_tag="VXB18_000812"
     CDS             21940..22545
                     /locus_tag="VXB18_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0382042.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22564..23808
                     /locus_tag="VXB18_000813"
     CDS             22564..23808
                     /locus_tag="VXB18_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0382043.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24031..24288)
                     /locus_tag="VXB18_000814"
     CDS             complement(24031..24288)
                     /locus_tag="VXB18_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0382044.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24330..26366)
                     /locus_tag="VXB18_000815"
     CDS             complement(24330..26366)
                     /locus_tag="VXB18_000815"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0382045.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26626..27543)
                     /gene="glyQ"
                     /locus_tag="VXB18_000816"
     CDS             complement(26626..27543)
                     /gene="glyQ"
                     /locus_tag="VXB18_000816"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0382046.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWANGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(28264..29025)
                     /locus_tag="VXB18_000817"
     CDS             complement(28264..29025)
                     /locus_tag="VXB18_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0382047.1"
                     /translation="MDNLYLVKDDSQLAAFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSSFNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEYFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTIDKLVENLG
                     SVQAVFDSYHLWANTDKTLPLLNWFVQQKLIEKEI"
     gene            complement(29298..30140)
                     /locus_tag="VXB18_000818"
     CDS             complement(29298..30140)
                     /locus_tag="VXB18_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0382048.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(30254..31645)
                     /locus_tag="VXB18_000819"
     CDS             complement(30254..31645)
                     /locus_tag="VXB18_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0382049.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31880..32257)
                     /locus_tag="VXB18_000820"
     CDS             complement(31880..32257)
                     /locus_tag="VXB18_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0382050.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            32490..33467
                     /locus_tag="VXB18_000821"
     CDS             32490..33467
                     /locus_tag="VXB18_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0382051.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQTHHT
                     MTEEVAAFAHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            33464..34546
                     /locus_tag="VXB18_000822"
     CDS             33464..34546
                     /locus_tag="VXB18_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0382052.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFDPLLTGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSNQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34610..35640)
                     /locus_tag="VXB18_000823"
                     /pseudo
     CDS             complement(34610..35640)
                     /locus_tag="VXB18_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(36024..37220)
                     /gene="tuf"
                     /locus_tag="VXB18_000824"
     CDS             complement(36024..37220)
                     /gene="tuf"
                     /locus_tag="VXB18_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0382053.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(38130..38999)
                     /locus_tag="VXB18_000825"
     CDS             complement(38130..38999)
                     /locus_tag="VXB18_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0382054.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(39223..39744)
                     /locus_tag="VXB18_000826"
     CDS             complement(39223..39744)
                     /locus_tag="VXB18_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0382055.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(39702..40310)
                     /locus_tag="VXB18_000827"
     CDS             complement(39702..40310)
                     /locus_tag="VXB18_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0382056.1"
                     /translation="MAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQ
                     LIGTSYNVTDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPT
                     TATVTANYYKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTT
                     YTLVATPANAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(40748..41704)
                     /gene="lytA"
                     /locus_tag="VXB18_000828"
     CDS             complement(40748..41704)
                     /gene="lytA"
                     /locus_tag="VXB18_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0382057.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(41708..42040)
                     /locus_tag="VXB18_000829"
     CDS             complement(41708..42040)
                     /locus_tag="VXB18_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0382058.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(42044..42460)
                     /locus_tag="VXB18_000830"
     CDS             complement(42044..42460)
                     /locus_tag="VXB18_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0382059.1"
                     /translation="MKIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            complement(42470..42733)
                     /locus_tag="VXB18_000831"
     CDS             complement(42470..42733)
                     /locus_tag="VXB18_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382060.1"
                     /translation="MLKVTKTRQLVTEFFAQDGDQQKLVKTTVINTDNKAVSTISETL
                     HDPELYANNRISMRKHEQELREMRYKIEDAILAELEADSEHKE"
     gene            complement(42793..43482)
                     /locus_tag="VXB18_000832"
                     /pseudo
     CDS             complement(42793..43482)
                     /locus_tag="VXB18_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159973.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
     gene            complement(43477..44043)
                     /locus_tag="VXB18_000833"
                     /pseudo
     CDS             complement(43477..44043)
                     /locus_tag="VXB18_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        12775 a         9741 c         8062 g        13465 t
ORIGIN      
        1 gtctattgaa aaatctccag actagagaac tcatatatag ttcctaatct ggagatttct
       61 catttgcact tttcttgtac aactttagtc catggtaaat aggcctctaa aacctctttg
      121 tttacgagag tttcctcgtt tggaagacat tctagaagat aggatagata tttctcacta
      181 tttagttgat gacgtttagc tgtttccaac aaactcataa taatagctct tgctttagct
      241 ccttcaaaac tttgagaaaa taaccaccct cgctttttta aactgagctt aggctaaaag
      301 agtccactgg actcttttac tccgtcccat aaccaatgat ttaatggcgc attcagctag
      361 attattggaa aggaccagat gtccgtcttt caaaatggtc ttaaaggttt cttcatactt
      421 gaggctgtat tcaattgccc ttcctagttt tgaacctgct aaaactgact gacggcggca
      481 ccaagcaaag aagtcttcta ttaggggttg gagctcttct tgacgtttct gtagtcgttc
      541 atcagctggc aaagcctccc agtctctttc caaggaaaat aactgatcac aataggctaa
      601 tcctttagct cctaaagatg atttatctgc ttgcttgggg gtcgcttcaa aaaacttcct
      661 tctcacatgc gcccaacatc caacaagtgc agcttcttcc agttgacgat aagcttctag
      721 cggctcgcag tttaccaagc ttagcgtcgc cttgctccta agccttggac tgctatcgca
      781 tagacagaac tagaggacta aagtcctaag ttactgccgc aacatatcac aatgcacata
      841 gccagaataa tctcctagga attcttgtac tactaaacca ctccgacgct gatcatggtg
      901 gtacagcgtg attgcttgat tctcagcttt cccagacaaa aaggtccaat agtaggtcag
      961 ctgactatca ctctctagca ccctataaga agtttcatct gcatgaagta agggcttgag
     1021 tcaatagtct cgttataaag gggctttagg aataggagct ttcacgattt tatcactcgg
     1081 atttttatca ctgcatgctt ggcatttgta agcgtgttgg atatgatcta tgcgttttaa
     1141 ttgcgcagga ataaagacca attcttgtcc ttgaagactc cctccaatct cttttagatc
     1201 tccctgacaa tcagggcaaa tcctctcttc tacttgatga tgaacttctt ctgaatcaaa
     1261 ttgggcaaga agagcttggc gtttcccttt agatttctta cgtttgtagg taatttcctc
     1321 tgtttcaact gggaacatct ccatcttcct cagatggaga ctcttcctca aaaaggttga
     1381 gttgtccaga ggggcaaaca cttttctcag aggattttcc atagagcttt tgagtcagat
     1441 aagccacttg ttcacgcaga agggcaagtt cattggtgag actatcaatt gtagcactct
     1501 gttgttgaat gattttcaat cttcttccat gagcttccct ctctgttttc taactttatt
     1561 atactaaaaa gaaagtcctc atttcaatag aaatcacgac tttctgatgg atttatagta
     1621 aaatgaaata agaataggac aaatcgatca ggacagtaaa atcgatttct aacaatgttt
     1681 tagaagcaga ggtgtactat tctagtttca atctactata tttttggagt gatagaaaag
     1741 cccttcataa gctagtctac ttgttcaggt gcgagagctt tgacatcctt ttctgtactt
     1801 agccaagtca gtctgccgtt ctcaaagcgt ttatatagta gccaaaatcc ttgaccatcc
     1861 cagtaaaggg ctttaaagcg gtctttacgt ccaccacaaa agagaaaaac ttgacctgag
     1921 aaaggatcta attcaaagtg ggttttaacc agataagcca gtgaatcaat gccttgcctc
     1981 atatccgttt tcccacatac gagatagacc tgtcctaggc tagatagatg aattgtcata
     2041 gagcaacacc ttatccaaaa gctgttctac catttcgaga ttgagagatt gaaaaaaact
     2101 tacttcaagc ttgccaatac gaattttaag cagaatatca tttctctttt tagaatcaaa
     2161 aagacgagat tgtggaatct ctacaggaac aataggttgt ggcattaaaa tatcctccaa
     2221 tagttttact ttactaatag tatacaggag gagctccatg aatgatagat accttgttat
     2281 gacgcgctta ctatattaga aagttggctc tctaattaaa ttaattctca ttatatatat
     2341 caaaagaccg cagcttgaaa actacggtct aattttttgt ccaaatgtaa accacttgga
     2401 actattattc aatttattct ttttagtaaa tgttcccgtt ttaatcccag ttacagtttt
     2461 taatcctctg taaccgttga ttttacaaag cttttaattt ttttgcgatt actcccactc
     2521 aactgttgca ggtggtttac ttgtaatatc gtagacgata cggttaacat gatccacttc
     2581 atttacgata cgtactgaga ttttttgaag tacttcccat ggaattttgg caaaatcagc
     2641 agtcatacca tcgatagaag tgatagcacg gattgcaatc gtgtagtcat acgtacgacc
     2701 gtcacccata acaccgactg aacgaacgcc tgtgttaaca gtgaagtatt gccaaatatc
     2761 gcggtcaagt ccagctttag cgatttcttc acgaagaata gcgtctgatt cacgaacggt
     2821 ttcaagtttc tcttcagtga tttcacccat gacacggata gcaagtcctg gtcctgggaa
     2881 tggttggcgc catacgatat ggtctggcat accaagctct gtaccaagag cacgaacttc
     2941 atccttgtaa agagtattga gtggttcaat caattcaaac tgcatatctt ctggaagacc
     3001 acccacgttg tggtgtgact tgatagtttg agctgtatcc gtaccagact cgataacatc
     3061 tgtatataaa gtaccttgag caaggaattt cacatctttg agcttgcttg cttcgtcatc
     3121 gaatacatag acaaactcgt taccgatgat tttacgtttt tgttcaggat cagaaacgcc
     3181 agcaagtttg tcaaggaaac gtttagcagc gtctgctttg acgatattca aaccaaactt
     3241 accaccgagc atgtccataa cttgatcagc ttcgccttta cgaagaagac cgtggtctac
     3301 gaagatacag atcaattgat cgccaatcgc tttttggaga agaaccccaa cgacagatga
     3361 gtcaacacca cctgatagac caagaaggac acgtttatca ccgacggttt cacgaatttt
     3421 tttgatctgc atgtcaatga aattatccat tgaccagtca cctttagcct tacaaatgtt
     3481 aagggcaaag ttacgaagga tatcatttcc gtatacagaa tgacgaactt ctgggtggaa
     3541 ttggataccg taaatgtgtt tatctgggtt ttcgatggct gcgtatgggc agtcagctga
     3601 tgtacctgta cgaacaaagt cagcaggaat ctcagtaacc gcatcaccat ggctcatcaa
     3661 aacagtctgt tcatcaggtg ttgattcaaa aagcgctgat ggtgtgtgag ttagggttga
     3721 ttgaccgtat tcacgatttc cagcatcacc tgcaggaaca acttttcctc caagtttatg
     3781 ggtcaataac tgcataccat aacagattcc caaaattgga attccgagtt cgaagatttc
     3841 tgggtcaata tcaaatgaac catcttcata tacagaattt ggaccacctg atagaataat
     3901 tcctacagga ttgacttcac gaacttcagc agctgaaatt ttatggcttt ttagttctga
     3961 aaaaacacca atctcacgga tacggcgtga aatcagctgg ttgtactggc taccatagtc
     4021 caatacgatg attttttcta catcttgcaa atcagttgaa atgttgctca tctttttcct
     4081 ttctcaaaag aaatatcttt tctcaatatt ctatcacaaa taagggcgaa ttaccaacta
     4141 aacaaggcga agtttgactt tttctagttt attggggtac aatagagaaa agatagaaat
     4201 gaagtgaaaa atatgctacc tgcttatatg aaaatccatg atcagataaa aaaggatatt
     4261 gacgagcacc gttgggctat tggtgagagg cttcccagtg aaagagattt agctgagcag
     4321 tttgcggtca gtcgcatgac cctccgccaa gccgtatctc tattagtcga agaaggcgtc
     4381 ttagagcgcc gtgtaggaag cggcaccttt gtttccagta ctcgagtaca agaaaagatg
     4441 cgagggacaa ccagttttac tgaaattgtc aaatcccaag gtaaagttcc ctctagccag
     4501 ctcatttcct acaaaaaaac cattcccaat gagcaagaag ttgccaagct aggaattttt
     4561 ccaacggaca atattatccg aatggagcgg gtccgctatg ccgaccaagt tcccctagtt
     4621 tatgaagttg cttctattcc tgaaaaattc attaaggact ttaaaaaaga agaaatcacc
     4681 agtcatttct tccaaacctt gcaaaaacat ggctatcgta tcggcaaatc tcaacagacc
     4741 atctatgctc gccttgctaa agaaaagatt gcccactatt tggaagttga aaaaggacat
     4801 gctattcttg gattgacaca ggtttcctac ctagaagatg gtactgcttt tgaatacgta
     4861 aaaagtcaat atgtaggcga acgctttgaa ttttatcttg aaaataatta gattaccacg
     4921 caaaaactct ctgtcacaga caaagagtct tttttatttt tctaagaata aatctttcaa
     4981 agaaatcaaa gttacagcaa acaatatcat tgccatacca agaaaatcaa tgggataaaa
     5041 ttgttcattc attattaaga aggcaaagaa aaccgccgat attggctcaa ttgaagccaa
     5101 caagcttgac ttgaccggtc ctatcagact ggctccttta aggaaagctg tataggcaaa
     5161 gacagtcccg ataaggataa tacctgcaaa cgcaaggaga aaatcaagac tagtcgggat
     5221 attggcctgt agaacccctg taaaaggaag ggcgaccaaa cctgctataa ccattcccac
     5281 accaatgacc aagctgctcc cccacttttt aatcaaggct atgggtaaaa tgatatatag
     5341 agcataagtc aaggcagaaa agagacccca gaacaggcca gcaggtgtca tggataactg
     5401 gtccaactgc ccatgtgttg cgatcaggaa ggttcctccg atggcgaata tgatggaaac
     5461 tatctctccc agtgtcggtg ccaccctatc cttgatacag ctataaatta aaattccgac
     5521 aggacaaaca tactgaagca ccgtcgctgt tcccgcattg gtctcctgaa tagcagacag
     5581 ataggcgaat tggttgagaa aaagaccaat cagagcaaaa ataagaagag acagcaaact
     5641 ctttctatcc tttaaaaaga ccagtatttt atcctttgca gtagcataag ccaagatcat
     5701 gagaattcca ccagcgatta aaagacgcaa gttggtcaag accagagccg aaattccgtg
     5761 tgccattagg tattggccac tcgttcctga caccccccaa gcaataccag ccacaactgt
     5821 tagtaaagtc ccttttaaac tatttgacat gtctctcctt actcttcttt acgaatcaag
     5881 ttcatcactt gattgcggtc taatatccat tgagctctct cgtccttttc ataggtacga
     5941 ttcgatagga aaatagtggc ttcttgcttc tgacgattcc acatgataaa ggtacctgta
     6001 tagcccgtat ggtctagcca atctccttcc aaattccatg ctaaagaacg ttccttgtca
     6061 tccaaaggag aaaaattttg atttaagtct cttgcaaaat catctgctaa atagtgttct
     6121 aaaaagattt gtaaatcctt tatagtcgaa aataaaccag cactcccagc atgtctaccc
     6181 aggagacgag ccttgggatc atgcactatg cctgcctcta cacctctaac tgttggaaca
     6241 gcaagctcaa ctggcccaaa cttggtttcc gtcattcccc aaggtttcca gacttgatcc
     6301 tttaaaatca catccaaatc ttgattaaaa attctttcca aaataaagcc caacagcaaa
     6361 aaatggacat ccgaataaag aaaggctggc tgacttcgtc tgttgagatg aaacatcgct
     6421 tcctttaatt caggggctgt taaaagatca cgattaggaa taaaaggatc aaggtctgtt
     6481 gcatgagtca agagctggcg aatagtgatg tctggataat cactctcagg taaaaaatct
     6541 attaccagtc tatcaatatc taattgacct atttcccaca agaaggtaca aactgtgcca
     6601 accccaacaa ccttgctgac actagctagg tcataaacta gtcctgcctc agtctgcaag
     6661 ccatgctctg ggtcactctg gcctaaatag aactctgtcc attgattgtc cttaaaatac
     6721 gcaaaagagg ctccgggata aattcctgcc tcgatttgtt cttctatttt tttaataatc
     6781 ttggtccact tcatacttct tcaaaccaca attcaacatt atttctatct ttacaaagga
     6841 agaatttttc agacttagga ataaaatatt cagtagactc aaacttctgg cgaagacttg
     6901 ctatgtctaa ttcattgacc aagaacttga gcatagataa gtcccaggta accgtattgt
     6961 ccacagtcaa atcctgcccc tgagctggaa taaaatcaag ggatgcccca atttcagatg
     7021 attccaagaa actttcgata tcagttggga gatgtaattc catagaaatc tcaaatttac
     7081 ttaaagaaat tgatgccaaa tctgtttgaa attcaggctt ttctcctact tctactagac
     7141 ttgctatgtc atcttccgca tgaatcaaaa tcaaatcatc ttctggtgag aaaatttcaa
     7201 aagcgtagcc attttgacct ttatataatc gatgaatcga atctgtttta gataagattc
     7261 cttcaatttc taagggattt tccaccttga caatcaatct agctagtttt tttcttccct
     7321 ctaccttacg agtacgcata ctgggagctt cttctaaaac cagcttttca agacccgttt
     7381 ggtcacctag tgacagaaag gccgattctt ctaacaaggc cttcattcca agggtttcaa
     7441 tataaaatgt ttcatttaat tttctattat tagcttttaa agtaggaata atccgtacaa
     7501 tctgatttac attcataaat tcctccgtca ctttttattt taaaggattt tagaattttt
     7561 tacaagatat tatgctcaaa tttaacatta tttagctatt tagtaaagat agtctttcaa
     7621 ggattttgac aaagcctgat aaccagcaat actgaggtgc agtccatcag ttgtatattc
     7681 ttttttgagt tggcctgctt ggtctgtcaa acaatcaaat actggcacaa attccacctg
     7741 catataggca gatgcaagct cttgataggc ttgattccag ttctgaattt tttcattcga
     7801 gcggatatag actgcctgct ggtactcctc tccctcattg acaggcaaaa tggaaagcaa
     7861 tttaatctct gtcaatggat aatcgcgagc aacggattga atgatagctt cgagattatt
     7921 gagagcctca ttcacaggaa catcctttcc gatatcattt gtcccaatca gaagaaaaat
     7981 tttatctact gctccaccat atagatgagc atcaaggttc tctagtaaca gtcctgtctg
     8041 atagccacga attcctcgat tgacaatcgt ctttgaagtc ccaaatagct cctgtagagg
     8101 ataatactcg acaatggaat ccccaataaa aagaatgttt ggttctacaa cagaaatgtg
     8161 atttaggtga cgatacttgg tttgaatttt ttcttgttcc tttaggagcc aattttctaa
     8221 taactgtact gccacttcat tctccttttt ctaaccagtt ttccaagact tgataaactc
     8281 ctccttggct gttggctggt gctagagcag tcgccacagc tttggctttc tcatcagcat
     8341 tttccatcgc ataggcaatt ccagccattt caagcatttc aacatcattt tcactatcac
     8401 caaaagccat gatttcttgg gatttcaagt cccagcgctt gagtaattcc tccaagcccc
     8461 atgctttatg aatcccagct tggaggatat caatgcaacc atagccactg gatacagctc
     8521 ggacacggcc atcaaagaga gtattgattt cttccaaaac cgaactcaaa cgttcctcac
     8581 caacaaccat gctcatcttg agcacaccac caaagaggtc agatgttaat tcatccacaa
     8641 attgcatccg ttggtagaat ttttcaatca tttctggagt cataaaactt tcaagatctg
     8701 taaaaatcgt accttccttg acaaaatcac ccttcatccc cgttacaaca aactggtcct
     8761 gacacgctcg acccttgaaa tgagccaaag ccttgttgac aatggcgtca tcccatgtct
     8821 gagcctgaat caattcattg ttttcaaaaa tacgagcgcc attagcaaca accagaacca
     8881 ctcgatccac caagggactc agtagttgtc tcatgcggtg aatttcattg cccgtcgcaa
     8941 tgacaaaacg aatgcccctt tgatccaact gatctaaaat cttttccaat cgtgggagat
     9001 caagctgacc tctagcatcc agcaaggtcc catccatatc tgtcgcaatt accttaatca
     9061 tcatttactt tcctctggat tcaagctaat accacttcaa tcccacatgt tcattcattt
     9121 ctttataggc tgtatcaatt cgttccttag tcgcttcatc taactggtca cgatgactgc
     9181 catcctctat aaaatcttcc aaaatataag tttggtaatg atacaaggga tatccttctg
     9241 gtgaaaaggt tccctttggt gttcgattga cccaagtagg atgatcttta gctgttccga
     9301 tagttgtttt tccatcattc ttcttgatgg tgacatccat gagaacacca cgttcagtcc
     9361 acttagcatt ctcttcatct cccatagatt caattcgttg attggaaatg aagttcccca
     9421 ttgaatagat aatgagtttc ttatctccat ctttttcaac cgtttcagat ggttcaacaa
     9481 cgtgaggatg ccctccaaag ataatatccg ctccccaatc gatcatcttg tgataaagag
     9541 ctttttgttc ttcagttggt tccaatcgat actcaacacc catctgaggc atgataatgg
     9601 tgatatctgc ttccttctct gcccgttcaa cttcagcctt catcttatct tcgtttaaat
     9661 ctaaaagata acgattatag tcttcctgag aaatatactg ctcaattcca ttgaaaccat
     9721 aggaataggc tgacaatgca accttgatac cattcacttc cttaatgacc agcggaacct
     9781 gatcacgtgg ttcgtgcgta taaactccga ttggagtgat tccagctttc tcaataatat
     9841 cggccgttga aataactccc tcaatttgcg aatccaaaat atgattatga gctaaatcca
     9901 gcacatgata acctgcctcc ttaatagcat ccataacttc agcaggagca ttaaagagag
     9961 gataacccgc taaataatga tccttattaa tggtttcttc aaaatcacca atagctaaat
    10021 ctgcttgctt gaaccaagga gtcacatact caaaattttc atgaaagtca taggtaccgt
    10081 cttctttttt agctgaaaag aaaagtccat cgtggtagag caaatccccg tgggccataa
    10141 ttctggcagt tttttcctct tcctactcct gagacttttg cttagttccc tcttgagaaa
    10201 tagtatctcg tttttgacta gtaaagagat tccttggaag ctttcaaaca acaagaccaa
    10261 gcccattgat aaaccaactg ctagcaagag tatcgccaca aatcccttat tgctccactt
    10321 gcgataactc ctaaaaagtt taccaagccc ttcataaaac gaaaagctaa accaccctga
    10381 tttcgatttt gtcttctttg tatcttcgtt ctccctactt tcttatgcaa gccttttctt
    10441 tttattatat cacagataag tatttctttc acaattgaat tgaacttccc atctattttc
    10501 tataaatcct aaatgccata atgctttcaa ttcttgtcat tttgtgatat catgtagagg
    10561 aaatgaacta atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta
    10621 actgcactaa acataatata aggagagaaa atgtctgcaa tagaacgtat tacaaaagct
    10681 gctcacttaa ttgatatgaa cgatattatc cgcgagggaa atcctactct acgcgcgatt
    10741 gctgaggaag tcactttccc cctatctgac caggaaatca tcctaggcga aaagatgatg
    10801 caattcctta aacattccca agatcctgtc atggctgaaa aaatgggact ccgcggtggt
    10861 gttggactgg ctgctcccca gttagatatc tcaaaacgca ttatcgctgt tttggtacct
    10921 aatattgttg aagaaggcga aactccacag gaagcctacg atttggaagc cattatgtac
    10981 aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc
    11041 ctgtctgttg accgtaacgt gcctggctat gttgttcgcc atgcccgcgt tactgttgac
    11101 tactttgaca aagatggaga aaaacaccgt atcaaactca aaggctacaa ctccattgtt
    11161 gttcagcatg aaattgacca cattaacggt atcatgtttt acgatcgcat caatgaaaaa
    11221 gacccatttg cagttaaaga tggtttactg attcttgaat aaagaaaatc ccgttgcaag
    11281 acggggtttt gtgttataat agaggcatga aaacaaatga tattgtctat ggtgtccacg
    11341 ccgttaccga agctctcctt gcaaatacag gaaacaaact ctacctccaa gaagatctcc
    11401 gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga aaagaaggtg tccatttctt
    11461 ggacatcaaa aaaatctctc tctgagatga ctgaaggtgc tgttcatcaa ggttttgttc
    11521 tacgagtgtc tgaatttgcc tatagcgagc tagattacat ccttgcaaaa acacgccaag
    11581 aagaaaatcc acttctattg attctagatg gtctaaccga tccccataat ctgggttcta
    11641 tcttgcgaac agccgatgcg accaatgttt caggtgtcat cattcccaag caccgtgctg
    11701 tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc tattgaacac gttccaattg
    11761 cccgagtgac aaacctcagt caaaccttag ataaactcaa ggatgaaggc ttctggacct
    11821 ttggaacgga tatgaacggt actccttgcc acaagtggaa tacaaaaggg aaaatcgccc
    11881 tcatcattgg aaatgaagga aaaggtatct ctagcaacat caaaaaacaa gtcgatgaga
    11941 tgattaccat tccgatgaat ggacatgttc aaagccttaa tgccagtgtt gctgcggcca
    12001 ttctcatgta cgaagttttc cgaaatagac tataaaaaag tttccagtca tctgattgga
    12061 aactttttta tgattaacta tgttctgtga taaacttgta ggcttcttga ccagcgatag
    12121 ctccatctcc aactgctgtt gttacttggc gaaggtcttt caagcgaaca tctccaactg
    12181 caaagatacc gtcgactgca gttttcatgt ggttatctgt cacaatccat cctgcctgat
    12241 cttggatatt caattcttta acaaaatcgc taagagggtt caaaccaaca tagataaaga
    12301 caccaccgaa ggcttgttct gtcacttgac ctgttttcac attttcaaat acgactgatt
    12361 ctactcggtt ttcacccttg atttccctta ctacagaatc ccagataaag ctgatttttt
    12421 cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg aagttggtca cgacggtgaa
    12481 caatggtaac agtcttagca aaacgagtca agaagagggc ttcttcaaca gctgaatctc
    12541 caccaccaac taccaataaa tcttggtcac ggaagaaagc accatcacac acagcacagt
    12601 aagaaacacc acgactgttc agttcttctt ctccaggcac tcccaaagga cggtgtttag
    12661 aaccagttgc tacgataact gtacgtgttt catatgtttg gtcatcagtc atcactttct
    12721 taaaatcacc atggtcttcg acattttcaa cataaccata aatgtgctca acaccaagat
    12781 tttcaagtgg ttcaaacatc ttttcagaca attcaggtcc actaatatta gcgtatcctg
    12841 ggtaattttc gatatcagat gtattattca tctgaccacc tggcagacca ccttcaatca
    12901 aagctacttt tagattgctt cgagcagcat acaaggccgc agtcatccct gcaggtccag
    12961 caccgataat aatagtatcg tacatataga ttccttcttt cttgttgtaa ctatctttat
    13021 tctaactctt tcttgtcaat cacgcaagga ttatgccttg aaaacaagaa ttaaactcat
    13081 aaccgcaaag gataatactg ggacaaccaa gactccaatc ataatcatat catagagatg
    13141 ggcttggcga gccctggctg tcttatcaac tcccgacatg gctctcagac caatccaaat
    13201 ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa ctctcgaaat ataaagaaaa
    13261 tagttgcagt agcatgattt ctctcatttc tatctttttt aaagagtaaa ctcagctagt
    13321 ccaactaact gagttttcct ttatctatta tatcaaatat aagtccgttt gtaactagcg
    13381 aagaattctt ttgtccgctc ttctttaggg gtgtggataa tctcatccgg agttccagac
    13441 tctatgattt tccccttatc taagaagaga attttatccg caacttgggc tacaaaggac
    13501 atgtcatgac tgaccaaaat catggtctga cctgacttag cagcatctgc aatagacttt
    13561 tctacttcac cgaccaattc tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca
    13621 tctggtttca tagcaagcgc acgcgctagg gcaacccgtt gcttctgtcc acctgataaa
    13681 tggcgaggat aatggttttc acggtccgaa agcccaacct tagccaactc ttccttggca
    13741 atcttagtcg cttcttggtc agataatttc ttgacaacaa ccaagccttc tttcacatta
    13801 tcaagtgctg ttcggcgttc aaacaaatta aactgttgga aaaccataga caacttacga
    13861 cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat caactgaaaa accatcaatc
    13921 tgaatagagc cactgtcagg tgtttcaaga taattgagac tgcgaagaaa ggttgatttt
    13981 ccagctcctg aagaaccaat caaggctaca acttcccctt tttgaatatc caagtccaga
    14041 tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac
    14101 gaaggtctcc tttcacatct gtttgcactg tatcaggtgc agaaatagcc atttttctct
    14161 cgatgaaacg accgaggctt tcaattccga tattgactac ccaataaaca agggcaacgg
    14221 agatgaagcg ttcaaaatag cgataatcag ctccacctag aatctgagct tgggcaaaga
    14281 cttccacaac acccgcacta aaagctagag atgttccctt ggtcaaaccg atgagggaat
    14341 taatcaaggt tggagtagct accaccgctg cattaggaat aatcactcgt cgataaactt
    14401 gcgctcgggt catacccaga ctgcgtgccg cctcaatctc accaggatta actgagagaa
    14461 tggctgcacg aatggtttca ctagcataag ctgcctcatt aaaggcaaag gcgacaatcg
    14521 caaaagctgc agctggaatc gcattgatat tgagaccagt tccccattgc tgattgaggg
    14581 ctttcaaagc caaagggatt ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc
    14641 cttttaagaa actaacaaag aaggcctgca agggatataa aatcttgaca cgattgatct
    14701 tcacaatggc aaaaagaagc gccaaaacca agccaaaaag ggcaccacca attgtcaaca
    14761 taattgttgt tggaagttgt tggacaattc tagggattcc atcaaagacc gaacgtaggc
    14821 taaacagctt gccatccgga atcaattgca tcaagttttg gtaccaatct gatgctaaaa
    14881 tcgttgtaac attcataaaa acatcctctt ctgataatga ttcattctac catgcttctg
    14941 ccgtcaatga aattatttgc tacggtcaga tacagacttt gtctacctac tagtttatca
    15001 tactttgaaa cagggaagtt atatatttta tctatcaaag agatagataa aaactatttc
    15061 agtcccagtt cttcataaga ttttcgataa ccgatttgct taacagttcc attttctact
    15121 aaaatgggcc gttttaacaa cataccgtca cttgctagca actcagccgc ttcttggttt
    15181 gacaaacttc ctaccttatc ttttagccct aattcacggt atttgatacc actggtgttg
    15241 aaaaattgct tcaattcaaa tcctgaggtt tctagccaat tcaaaatgac ttcttggcta
    15301 ggtgtttctt ccacgatatg gacggcttta tagtccacac ctaattgatt taattcttgt
    15361 tttgcttttt tacaagttga acatttgggg tattcgataa attctaacat gtgcttctcc
    15421 ttctatttgt ttatatcttt aaaatctacg ccttcatgct ccaagagcca agctttcttt
    15481 tccactcctg cagcatagcc tgtcagacgc ttgcctgctc ccaacacacg atgacaaggt
    15541 actaggatag accaaggatt gcgtcccact gctccaccaa ttgcttgagc agaagccact
    15601 tgcaggtctt gagcaatttg tccataggtc actgtctgac cataaggaat gccctgtaaa
    15661 tagtcccaaa ctctcttttc aaaattcgtt ccgattggcg ccaagagcaa gttggataaa
    15721 tcctgaggct tgcctttaaa gtaatcatct aagcaagcaa taactgggtc taaaatagga
    15781 tgactaacaa cttcttctat cgtttcatct cctagtcccc tctcaaaatg cttctgctcc
    15841 tgaacccaaa ttccatacaa ataatggtca tcagctacaa gtgatagaat accaattggt
    15901 gaggagtaga ggatttttac atacttcttt tgcattattt ctttaatttt tgataggcca
    15961 agcgttcgcc atctactggc accttaccaa cttgtttaaa accaagtttt tcaaaaatat
    16021 gttgcataac cttgttttca gcatgcgtat ctgagcgaaa atcaagataa tcaaaacctt
    16081 caatcaagcc ctctaagaag gtttgagcaa ctccttttcc ctgcacatct gctgccacag
    16141 caatacggtg aaagactaga tactctgact ctccagcttg ccagtttccc tcataaatag
    16201 cttcataggc ctcctctgga ctcttggtca cagcagcata ggctagcagt tctccctctt
    16261 ccaaggctac gtaggcttgc cctgagatga tatcatcgat aataacatct gcatttggat
    16321 agccattttg ccactggtta ctaccagcat ctgctaaaca ttttttggca tcctctatca
    16381 cctgcatgat ggcacctact tcatttggaa aagctaaacg aatttccatc ttttttcctc
    16441 atttctgact agtttctccc atcatagcat aatttaagtc tttctacaag cagttaaaac
    16501 ttgactttgt atttttgtta ttttataatc tagttatcaa aactatataa aaaggagttg
    16561 aaaatgaaaa ctaccttttc ctacccaaaa tgggcagaaa ttccaaacat tgacctctat
    16621 ctggaccagg ttttgctcta tgtcaatcag gtctgcgccc ctatctctcc taataaagac
    16681 aagggcctaa cagcatctat ggtcaacaat tatgtgaaaa atggttacct gacaaagcct
    16741 gacaaaaaaa aataccaacg ccaacagatt gcccgtttga ttgctatcac aaccctcaag
    16801 tctgtatttt ctattcaaga aatagcccag acacttaata ctctacaaac tcaagcaagt
    16861 tcagaccaac tctacgatgc ttttgtggac tacatgaacc aaggaattaa cccagctaac
    16921 cctattatcc aaaccagctg ccaaaccatt aaactctatc atcaaactct agacttaatc
    16981 gatcatactc aagaggaggt aatccaatga acactagtct taaactcagc aaacaactca
    17041 gttttggaga ggagattgct aatagcgtga cccatgctgt aggtgcagtc atcatgctta
    17101 tcttgctgcc tatttcatcc atctatagtt atgaagcaca cggattttta tcctctatcg
    17161 gcgtttccat tttcgtcatc agtctctttc tcatgttcct atcatccacc atttatcact
    17221 ctatggccta tggttcgacc cacaaatatg ttttgcgaat cattgaccat tctatgattt
    17281 acgttgccat tgccggctca tacacgcccg ttgtcttgac cttgatgaat aactggtttg
    17341 gctatctgat tattgtcatc caatggggaa cgaccatctt tggtattctc tataaaatct
    17401 ttgctaaaaa ggtcaatgag aaatttagcc ttgctcttta cctgattatg ggctggttgg
    17461 ttctggctat cattcctgcc attatcagtc aaacgacacc cgttttctgg agtctcatgg
    17521 taactggcgg actctgttat acagttggag ctggatttta tgccaagaaa aaaccttatt
    17581 tccacatgat ttggcatctc tttatcctag ctgcgtccgc actccaatac atcgctattg
    17641 tttattacat gtaaaaaagt tgagaagttc aatctcaact tttttcttta cacatattga
    17701 taaagtactg gtgcaagcgc acatcatcag tcaattctgg atgaaaagaa cttaccaaca
    17761 tatttttttc ttgggctgca acaatttgat tgttcactgt tgctagaatt tctacaccct
    17821 caccaacact actgataatc ggaccacgga taaaggtcat tggaatcttg ccaactccct
    17881 tacattctgc ttccgtgtag aaacttccta attggcgccc ataagcatta cgctcgacca
    17941 ccatatccat agttcctaga tgactctctt tctgagaagt gatttcctta gccagcaaaa
    18001 ttaagcccgc acaggtccca aacactggta agccagatag aatggcttct cggatgggaa
    18061 gtagcatgtt ctggtcacgt aagagcttgc ccatggttgt agactcacca ccaggcaaaa
    18121 tcaaacccga caagtcactc tgatcttgct gaaaatcatc tagatttctg agttctacac
    18181 tctcgacacc taattgatct agcacttttg catgttctgc aaaggcccct tgcaaggcca
    18241 atattccgat tttcatctat tttcctcgtt cagccatgag aatttggatt tcattttcat
    18301 taataccaac catggcttct cctaaatctt cagagatttg agctaggatt tgaggattac
    18361 ggaagttagt cacagcctta acaatggcac tcgctcgttt aacaggatct cctgacttga
    18421 aaatacctga accgacaaag accccctctg cccctagttg catcattaac gcagcatctg
    18481 ctggcgttgc aacacctcca gcagcgaaat ttacaactgg caattttcca tgttcatgaa
    18541 catattggac caattctaca gggacttgca aatccttggc agcaacataa agctcgtcct
    18601 cacgtaagtt ttgaatgcgg cgaatttcct gattcatcat acgcatatga cgaacagctt
    18661 ggacgatatc ccctgtccct ggttctcctt tggtacgaat catggaagca ccttcagcga
    18721 tacgacgcaa ggcttcaccc aaatccttag caccacagac aaaaggaact tggaattctt
    18781 tcttgtccac atggaaacgg tcatcagctg gagatagaac ttcactctcg tcgatataat
    18841 caatttcaat agcctctaaa atctgagctt caacaaaatg cccgattctg accttagcca
    18901 ttactggaat actaaccgct tcttggattt ccttaatcat ctttgggtcg ctcatgcggg
    18961 aaactcctcc agctgcacga atatcagccg gaattcgttc caaggccatc acagctgccg
    19021 caccagcagc ttctgcgata cgagcctgtt caggattctg cacatccata ataacaccac
    19081 ccttgagcat ctgtgccaag tttttattta gttcataacg attttcagtc atttgtttta
    19141 tcctcatcat ttgtattggt agctaccttt tcattttaag tcagaacaga atgaagcaca
    19201 agataaaaaa actataattg tatggggaca aattagctaa aaactatctg accttaactt
    19261 aaggccagat agctcattca tttttatttt tcagccgtaa gggcagccat tgtgatgtag
    19321 ttgtatggtt tgttgaagtg tggcaagaag aagaggtctg tcaatgccaa tttatcaatt
    19381 gtcacatgct cttggatagc aagtgagaac atgtggattc ccatgctaat tgcaatatca
    19441 tgtgaaacca tttgggcacc aagaatttca cggctatctt tgtcaaagac aatcttaatt
    19501 gctacttcat ggttgtcatg tttcatgaat tctggttttt gaagatcgtt aaagcctgtt
    19561 tcagttgcgt tgtaaccagc agctttcgct ttttcaagag tcaaaccagt tgaaaccatg
    19621 tgaagaccgt agattgagat accatttgaa ccttgaacac cgattccttc caattcatgt
    19681 ccacaagcat tgtaggcacc aacgatacca gtgcgaacag catttgaagc aagagcgata
    19741 tagcttgtat ctttacgagc attgtcataa acagtcgcac agtcaccaac agcgtaaacg
    19801 cctgggatag atgtttcttg tttcttgtct acaaggaagg caccgttgcg gaagagttcg
    19861 atcttaccat ctgcaagggc tgtgtttgga cggaaaccaa ctgcaaggat aaccatatcc
    19921 acgtcaaagc tttctttgtc agtaatcaag cgttcaactt taccgtcacc ttcgattgct
    19981 ttaacagttt gacctagagc caagcggatg ttgtgatctt ccaagttctt cgccatcatt
    20041 tgtgtgaagt ctttgtcata gtaaccgttc aagacagtat caacgatatc aacaaggaca
    20101 acttcttttc caagacgttc aaaggcttca gcaagttcaa caccgatgta accaccacca
    20161 acaacggcga tacggtcgag gtgttggctc ttgtcagaaa gtttattgat aacttcttca
    20221 gcattttggt acaatttcac gaattgtacg ttttcaagag ttgctttaaa ttcgcggttt
    20281 cctttaacaa tttcaacacc ttcgattggt ggcaagattg gtgtagaacc tgtagcgaaa
    20341 atcaattttt cgtatgattc tttgtgctct tttccttcaa cttccgctgt aactactttg
    20401 ttatcatagt cgattgaaag aacaggtgag ttcatgtaaa ctttagcacc tttagcttcc
    20461 aatttttctt tatcagaata gaacaagcct tcagcaccgt caatttgttc accaatccaa
    20521 agagccattc cacatcctag gaaagagatg ttagagtttt ggtcaaatac aacaatttcg
    20581 ttctcatttc caaaattatc caacatggta ttgatacatg ctgtaccagc gtggttagca
    20641 ccgactacaa cgattttact cataaaaatt tcctgccttc attctaaatt taccttacta
    20701 gtataccatt taccgttagc gtttacaagg ggggtactat tatttcagca ttttttatca
    20761 aaaataattc cccatttatc ctgttttcaa gcctcatgaa ttttatgagc atatttcttg
    20821 actttttcca aattttgttt gtgaaaattc taactttatg gtattataat aacatgaaaa
    20881 tgaaatgtaa gggcttcaat ttagataatt attttatatt acaacttatt ttctataaga
    20941 gaaaggagtt ggtagcttga ctcttcgttc acattctgaa cggctaatgg ggactactat
    21001 cactatttca ttagtggatg agcaagccga tatctttctc caaaaatcct ttgacttgct
    21061 caaagagctt gaataccgct tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa
    21121 ttatcaagca ggaatatccc ccgtcacggt tcatccagac ctgtttgagc tgatttcact
    21181 tgggttagag catagcctag cgctctctag ccacctcaat atcagcattg gtcccttaat
    21241 tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc cagcctcaag aaattgaatc
    21301 ggtgctgcct ctaatcaatc ctcatggtat cgagttagat tcttctactt ctactgtgtt
    21361 tttaaaacag aaaggaatga agatcgatct aggttgttta gccaaaggat acagtgcgga
    21421 taaggttgcc caatttctta ggaaagaggg ggtgacttct gccttgatca atctgggagg
    21481 gaatatcctg accattggaa aaaatcaggc aagaggggat aacccatggc aaatcgggat
    21541 tcaagaccca gccaatccga ggggaaatca tttaatgacc atccctgttg tcaataaatc
    21601 tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc gatggacaag attaccatca
    21661 catttttgac agtcaaacag gatatcctgt tgaaacggaa ctagcgagtc taacaatcat
    21721 ctctgataaa tcagtcgatg gcgaaatctg gacgactcga ctctttggag aaagacctgc
    21781 ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa gtcatcctca tcgataaaga
    21841 aggccaccta agctgttctt caggaattcc tactctatag agacaactgt ttcaatggaa
    21901 ttttaaaatt gtattatgta aaaagagaaa ggaaatctca tgttaaaact tattgctatt
    21961 gttggaacaa attcaaaacg ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac
    22021 tttgctgaca aagctgaaat tgagcttgtt gaaatcaagg ccattcctgt cttcaacaaa
    22081 ccagctgaca agcaagtacc tgctgaaata ttggaaattg ctgctaaaat cgaagaggca
    22141 gatggcgtta ttatcggtac tcctgagtat gatcactcta ttccagctgt tttgatgagc
    22201 gctcttgctt ggttgtctta tggtatttac ccacttttga acaaaccaat catgattaca
    22261 ggtgcttctt acggtacgct tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg
    22321 aatgctcctg aaatcaaggc aaatgttctt ccagatgaat tcttgctctc acactctctt
    22381 caagcattta acccaagtgg cgacttggtt gaccttgatg ttatcaagaa attggatgcc
    22441 atctttgatg acttccgtat ctttgtaaaa atcacagaaa aattacgtaa tgcacaagaa
    22501 ttacttcgca aagatgctga agactttgac tgggaaaatt tgtaagatag gagaccaaaa
    22561 agaatgaaat ttgttggact tgttggatca aactacgatc aatcatataa ccgtaagctc
    22621 ttggaattta tccgtcgcta cttcaaactc aaatttgaat tagaagttct tgaaattgac
    22681 gaagttccaa tgtttaacca agatgaaaaa tgggatgaaa gtttccaatt acgtttcttg
    22741 tataacaaga ttacacgtgc agatggtgtt atcattgcta ctcctgagca taaccacact
    22801 atctcagctt cactcaaatc tgtacttgaa tggctttcat acgaagttca tccatttgaa
    22861 aacaagcctg ttatgattgt gggtgcatca tactatgacc aaggaacatc acgtgctcaa
    22921 gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg cctacacgct tccaggtaac
    22981 gaattccttc ttggtaaagc taaggaagct tttgataaca acggaaatat caccaacgaa
    23041 ggcactgtta aattccttga aacttgctta gataactttg ttaaatacgt aggagtcgtt
    23101 tcgaaattga aaaaaccaaa accaatcgaa tcagaagact tggattgtgg aaaaccaatc
    23161 gctacaacca tcacagaagt tgaccctgac gatccagaat gggtagaaaa agttgcagca
    23221 atcactggtg ctgtttctgg tgatacctat gtcaaattgg accacggtat cctaacagtt
    23281 aaccaaattg atatgttctt gaaagctatg ccatttgaat tgacatacgc tgacgacaac
    23341 aaccaattcc tctactacaa caacgctcac caagatccag acactatgtt cgctaaacgt
    23401 gtaccacctc aatcaggtag ccgtatgtcg actgttcatg gttctcttcc accagcacgt
    23461 atgaagaacg tagagtgggt tatcggaaca cttcgcaacg gaaaccaaga atacgtccgt
    23521 acgatcgttc caggttctcc tgcaggtgtt atcaacactc acaactacca agcaatgtac
    23581 tatcctgatg gatcatacgc tggtatcaat gaaatcgtct ttaacttcca accatggctt
    23641 gactggtacc taaaagagac tggtcaacgt ttggtgggtg gtagcggacc atttgctcct
    23701 gctgccggag gtcatggaga cgccgatgct acttctggcg cttctgattc aggggatgct
    23761 ggaggccacg gtggtgacgc agacgctaca gccggtgcaa gttactaatg atagttttta
    23821 ggaaccatta tggttccttt tttagcgaaa aaagactagc aaacacaaac tgctagtctc
    23881 tttgttatcg tttcatctat ctttgttaaa agaaagaata catatactca atgaaaatca
    23941 aagagcaaac taggaagcta gccgcaggct gtacttaagt acggcaaggt gaagctgacg
    24001 tggtttgaat ttgattttcg aagagtatta ttatgaattt ggatcatcaa gactacggcc
    24061 atgtaatcct ttttcacgtt gtacttggcg tagtttttct ggtgtaacat cgtttccttc
    24121 ttcgtccaca attttgattc cttcaatgtg gtgacgaaca gcgcggcgat aaccttcgat
    24181 gtactcctca cgtagtttgg cttgttccac tttttcttct gatgttaagc cttctgtttt
    24241 tttcttttta gcaagctcat tgatacgagc aatttttttc ggatccattt cttctccttt
    24301 gtaataagat aaagtctgtt tatcaaattt tatttagtgt taatttggtt aaaacaagca
    24361 aacttagctg ctttcttggt tagttgtgac aagattgcca aacgattttg acggacagcc
    24421 tgatcttcag ccattaccat agtattttca aagaaagcat caatgactgg gctaagcgca
    24481 aagagttgtt tcaattgctg acttgcaggt cctgataaaa cgagtgtttc tactgcttct
    24541 gccaaagctt tttcttggtc attctcaaat agtgctgaat caactgtagc aaccccttct
    24601 gccttctcag ccaggttaaa ggcacgagaa agtgattcaa cagatggttt aaaatcttct
    24661 tccttgctta cttctacgag agcacttgct gcttccaaca tatctgccac aacaaagttt
    24721 gaacctgcaa gaactgcttc tttgatatct tttggagtag agcccatcat cttatcaaca
    24781 cgagccttga taaagtccat aacctctgct ttattttcat aagtcaaact gtcaaatttc
    24841 aatgcataaa ggctatcaat cagctcatcc atagcaatgt gccaaccaaa ggcatccaag
    24901 atacgaacca caccttgagt tgcacgacga agggcataag ggtcattaga acctgatgga
    24961 atcaatccta ctgagaagaa actcaaaatc gtatccaatt tgtctgcaat ggctagaact
    25021 gcgccgacct tgctctctgg aagttctcct tcagctgatg taggcatgta gtgttcacga
    25081 atagcagctg ccaccgctgg agtttcacca gcaagaaggg tgtatttttc acccataatt
    25141 ccttggagtt cgtcaaattc accaaccata cctgtcaaca agtcaaactt gtaaatggct
    25201 gctgcacgag caaggtcaac tgtttcatcc actgacaaac cagctttttc tgccaaaagt
    25261 acagtgattt gacccgtacg aatcatgtgt tcacgaaggg aaccaatctt ctcatggaag
    25321 gtgacattgt ttaatttttc aacaagatct gaaatcacca atttttggtc ttcacgccag
    25381 aagaattctc cgtcttccaa gcgggctacc aagacttttt catttccttt gatgacattt
    25441 ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt ttggcaagag ttttccatct
    25501 tgatcacgaa caacaaagta acgctggtgt tccttcatag aagtcaccaa gacttcttct
    25561 ggaacttcaa ggtatttagc atcaaaactt cccatgaagg cagttgggta ttcaaccaaa
    25621 ttcaagactt cattcagcaa atccgcatca atttcgatac gtacaccatg ttttgcctca
    25681 atttccttga tttggtcaac aatcatttgc tcacgttcac atggatctgc gattacaaac
    25741 tgcttacgaa ggtcttcttc atagctcaat gctgactgaa ttttggtttc tttccccaag
    25801 aaacgatggc cacggctcac acgacttccc ttgatatcaa ggaaatccaa gtcaaactct
    25861 tgctcatcca agagaacagt taaagtgtga acagggcgga tgtattcaaa gctatttcca
    25921 gcccagtgca tgctgacagg gaaagtcaat gacttcaaga catctacaac accaggaaca
    25981 atggcttcaa ctgattgacc aacttcttcc ttagtgacat agacatattc ttcacccttg
    26041 atttcacgga attcgatatc ttcaacagtc aaacctttcc cacggacaaa tccttgagct
    26101 gctttggtga agtttccatc actatccaag gcaattttct ttgctggtcc cttgaaatct
    26161 tctgtcaaat cagactgttt gtctgataaa ccagtcacac gaacagccaa acgacgtggt
    26221 gttgagaagg tttgaatggc ttcaaaagac aggcggtttt ccttgaggaa ggctgccatt
    26281 ttttcgccta gttgtttttc acttggtgtg acaacatagg ctggtaattc ttcaagaccg
    26341 agttctacta ataagttttt tgtcatgttt tttcctttac attttcttca atcttttttg
    26401 atatgcacct taggtactgg ggacgtcgct aactaactct gtgagtctgt atggaaatcc
    26461 aatgctaaat ttatcaagat ttccaacaat ctcatcaaag tggatttagc tgactgattt
    26521 ttgaacctaa ggtttcaaaa atccccacat aacagtacgg cggtgcatat ccctctagca
    26581 agtcttcgac ttgcctctaa cgattttaga gtacagtatt actcactatt ctgcgtcttc
    26641 tgctaaaagt ttaactcgtg tttcttcatc caaaagtggg taacctaggc gtttgcgttc
    26701 tgcaacaaag gttttggcta caacacgggc caagttacgg atacgagcga tatagcctgc
    26761 acgctctgtt acagatacgg caccacgcgc gtcaagcaga ttaaaggtat gtgaacattt
    26821 gagaacatag tcataggcag ggtgtaccaa gccttcttct aatgcacgac cagcttcttt
    26881 ttcaaactta tcaaagtttt caagcaacat ttcttggtcc gaaatttcaa atgaatattt
    26941 tgagtgctca tactcaggct ggataaagat ttctccgtat tttacaccat tagcccactc
    27001 gatatcatag acagagtcta cttcttgaat gtaagaagcc aagcgctcca aaccataggt
    27061 aacttccgca gtcacagggc cagttgccaa tccaccgact tgttggaaat aagtgaactg
    27121 agtgatttcc attccgtcaa gccaaacttc ccaaccaaga ccagctgaac cagttgatgg
    27181 gttttcccag ttgtcctcaa caaaacgaat atcgtgctcc aaaggattga ttcccaattt
    27241 ttccaaagac tcaaggtaaa gttcttggat atttgatgga gaaggcttca tgaccacctg
    27301 gaattggtgg tgttggtaga gacggttagg gttttcccca taacgaccgt cagcaggacg
    27361 acgtgatggc tctacataag ctgcattcca tggctcaggt ccgatagcac gaaggaaagt
    27421 gtaaggactc attgttcccg cacctttttc attatcataa gcctgcataa gcatacaacc
    27481 ttggtcattc caaaattgtt gcaaagtcaa aataatttct tgaaatgtta atttcttaga
    27541 cattgaatac tccttaataa aaaataatta cttgcgacac gagtctgcct cgtcgatcat
    27601 acgaggcaag acgagttagt actgcgtcta gctcaggcac tctagtgctg agcgtggagc
    27661 agcccgactg taaggaggtt tctgccactg atgcagtgaa atgttaattt cttagacatt
    27721 gaatactcct taataaaaaa taatttcttg cgacacgagt ctgcctcgtc gattatacga
    27781 ggcaagacga gttagtactg cgtctagctc aggcactcta gtgctgagcg tggagcagcc
    27841 cgactgtaag gaggtttctg ccactgatgc agtgaaatgt taatttctca gacattgaat
    27901 actccttaat aaaaaataat ttcttgcgac acgagtctgc ctcgtcgatt atacgaggca
    27961 agacgagtta gtactgcgtc tagctcaggc actctagtgc tgagcgtgag gcagtccgac
    28021 tgtaaggagg tttctgccac tgatgcagtg aaatgttaat ttcttagaca ttgtttactc
    28081 ctttttatat aaattacttg cgacacgagt ctgcctcgtc gatcatacga ggcaagacga
    28141 gttagtactg cgtctagctc aggcactcta gtgctgagcg tggggtagcc cgactgtaag
    28201 gaggtctctg ccactgacgc agtgaaatgt taatttctta gacattgttt actcctttag
    28261 tttttatatc tctttttcaa ttaatttctg ctgaacaaac caatttaaca agggaagagt
    28321 tttatctgta tttgcccata aatgataaga atcgaagacc gcttgtacac tacctagatt
    28381 ttctaccaac ttatctattg tcaaaaaact acgccagtat tcgtaaaaaa tacttgcata
    28441 attcttatca taagtcgaag aaccaaaatc attcaatgaa tgccaaccat acttcttctg
    28501 aaaaagttct acaagagact gattacaaat tttttccgct tgaaattcct cttctgtcaa
    28561 gaaatacttg cgactaatat attcaaccat cccctcttca aaccagatgt aagagtcgta
    28621 accatcaaaa tcatctaaaa aatactccga ccaatgagct aactcatgtc ctacaatctg
    28681 taagaggaaa ttttcagata aagaatgata atggctttct attgcttgag tttgctgaga
    28741 acactcgtag tccatcaact gatacaaata caactctttc catacagcta aatcaggcgt
    28801 cataaccatt cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt
    28861 agcagcatta aaacttgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt
    28921 ctttaaaaaa gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa
    28981 tgcagctagt tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt
    29041 cacacaatag actaaataag caaaagaacc gcgtccgaca atcctaggtt gatttaacct
    29101 aggggcgtca gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta
    29161 cagaaagcgc cagcccttta ttttgcccta cttggctccc actatcccaa gctcgcttga
    29221 agaacgccat aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca
    29281 attcttttta tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca
    29341 gcaatcgttt ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga
    29401 ttagcttgaa tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag
    29461 ctccaggcca aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact
    29521 tgcttgctat caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc
    29581 ttttcacgac agtaagctac gacttgatct tgatacacac ctggcgccaa gcgaacttga
    29641 ttgaccgcag gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa
    29701 ttgctaacgc cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa
    29761 acttccgcat tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa
    29821 tgaatcaaat acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct
    29881 tgacgagttt gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct
    29941 tcacgtggaa ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc
    30001 gccgccgtat caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct
    30061 tcttctccat ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta
    30121 tttaattgat aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa
    30181 acatttttta agtagtacta tcttctgtaa aaaataagtc tgtcaaatat ctaacagacc
    30241 tattttttct tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat
    30301 tgagcatctc tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc
    30361 ttggcaaggc attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag
    30421 ctacttgatg ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac
    30481 tatccacatc ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag
    30541 caccataagg tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct
    30601 cagtatcagt aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc
    30661 tccaactatg gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat
    30721 tcccagaaac atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg
    30781 tctctaatac ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa
    30841 ctttttgata tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt
    30901 acgaagattg gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt
    30961 caaccacagg acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag
    31021 acaagtcttg gtcagagaag ttttttacaa tctgctcact ctggtcttgc tctatttttt
    31081 tatcctctat gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg
    31141 aaaacagttg gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac
    31201 tggtcttttc agtctcttca accttaaaag caactaaatc atagatttgt ttggtcacat
    31261 tacgattaac gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat
    31321 tgtccttact ttctagcttg tccttaacat cttgatttat caactcccta acagaggaaa
    31381 tcactttctc cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat
    31441 gctccttctg atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct
    31501 tttgctcaaa acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa
    31561 tagaaattgc taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc
    31621 cacgtcctag tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa
    31681 tgatacaatt tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca
    31741 acatccgtat ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag
    31801 ctagaatagt agacctatac ttctaaaaca ttgttagaaa tcgatttgat tgtcctgatc
    31861 gatttgtcct gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga
    31921 agtaattact atcgacaatt gcgatagcgt atactggtgc gatttgtttg tagctctggt
    31981 gggtatcacc ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat
    32041 aagcccatag gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt
    32101 ggattccatt atctaactcc gccaagacgt ctatactagt atagaaatcc tgcgctgagt
    32161 agggcatgga aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg
    32221 gcaagtccag catatcgcgg ataaattgac aaatcattag ttgggctgat acccggatgt
    32281 ctgagaatcc tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga
    32341 ttctatgctt ctatctattt attcggaaaa gaaggctttt cttcagaaga aagctaatag
    32401 cttatttgaa attttctcct ctctgttgga tagtcccgtc tatctatgtt ataatgaaag
    32461 aaggatttaa aatcggaaaa ggagtattta tgctaaaatt aggtgtcatc ggaactggcg
    32521 ctatcagcca tcatttcata gaagcagccc ataccagtgg agaataccaa ctggtcgcaa
    32581 tctattctag aaaactagaa actgcagcaa cctttgcttc tcgctatcag aatatccaac
    32641 tattcgatca attagaagtc ttcttcaaat cttcttttga tttagtctat atcgccagtc
    32701 caaactcctt acattttgct caggcaaaag ctgccttgtc tgctggtaaa catgttattc
    32761 tcgaaaaacc agctgtcact caaccacaag aatggtttga tttgattcaa acagctgaaa
    32821 aaaataactg ttttatcttt gaagcagctc gtaattacca cgagaaagcc tttactacta
    32881 tcaaaaactt tttagcagat aagcaagtgt taggagcaga tttcaactat gccaaatact
    32941 cttccaagat gcctgacttg ttgactggac aaacaccaaa tgtcttttca gaccgttttg
    33001 ctggtggagc cctcatggat ttggggattt atcccctcta tgctgctgtt cgtctttttg
    33061 gaaaagccaa tgacgcgact taccatgctc aacagcttga caatagcatt gacctaaatg
    33121 gagatggtat cctcttctac ccagactatc aagttcacat caaggctgga aaaaacatca
    33181 cttccaatct tccttgcgag atttatacaa cagatggaac cttgactctc aacacgattg
    33241 agcatattcg ctcagctatt tttaccgacc accaaggaaa tcaagtccag cttcctatcc
    33301 aacagactca tcatacgatg actgaggaag tcgctgcatt tgcacacatg atccagcaac
    33361 cagatctgaa tctctaccaa acttggctgg atgatgcagg ctctgttcat gagctactat
    33421 ataccatgcg ccagactgct ggtattagat ttgaggcaga aaaatgaaaa ccaaactacc
    33481 gactgaatgg caagaactga gtgaccaact cggtttccaa gaattcaccc ccattcaaac
    33541 tcaactattt gatccccttc ttactggaga aaacctccta ggagtgagcc aaaccggaac
    33601 tggtaagacc ctagcgtatc tcctaccaag tcttctcaga ctacaaaaga aaaaagccca
    33661 acaactcttg attctagcac caaacacgga acttgctgga cagatttttg atgtatgtaa
    33721 aacgtgggca gaagctatcg gattgactgc tcaactcttc ctttcaggtt caagtcagaa
    33781 acgacaaatt gaacgcctta aaaaggggcc agaaattctg attggaactc ctggccgtat
    33841 ctttgaactc attaaactta aaaaaatcaa gatgatgaat gtggaaacca tcatcctgga
    33901 tgaatttgac caattactag atgattctca gattcacttt gtagaaaaaa tcactcacta
    33961 cgcacctcgt gaccaccaac tggtctacat gagtgccacg accaagtttg atcaagaaaa
    34021 gattgtgccg aatacacgca ctattgatct ctctaatcaa aaattggaca atatccagca
    34081 tttctacatg caggtagacc aacgtcatcg agtggatata ctacgaaaac tggctcatgt
    34141 agaggatttc cgtggtctag tcttcttcaa tagcctgtca gaccttggga atgccgagga
    34201 aaaactacag tatcgtgata tattggctgt ttccctcgct agtgatgtta atgttaaatt
    34261 tagaaaagtc atcttagaaa agtttaaaga taaccaacta accctgcttc ttgcaactga
    34321 ccttttggct cgtggaattg atatcgatag cctagaatgt gtcgtaaact ttgatattcc
    34381 tagagatagc gaaacctaca cacaccgtgc tggccgtact ggccgtatgg gcaaggaagg
    34441 atatgttatt actctcgtca ctcatccaga agaaatcaaa aaacttaaaa agtttgcaag
    34501 tatccgagaa attgtcctaa aaaaccaaga actctatatc aaataaagcc ccattgctct
    34561 atacacatcc agtgtatgga gcttttttac aagcaattca attttatact catctgcttt
    34621 caaaaagcat tctagtccat ctccgattaa cgatgggctt tatcacctcc ttctccagtc
    34681 cttgtatgat atcttgaagt tgattcatga catcttccaa agttcgaaag gctttattct
    34741 taaatccacg tttacgaatc tctttccaca cttgttcaac ggggtttatc tctggtgtgt
    34801 atggaggaat aaatgcaaag ccaatattag tcggaatttt taaggtactt gatttatgcc
    34861 atatagcatt gtccataacg agtaaaagat aatcatctgg ataagcttgt gaaagctctt
    34921 ctaaaaaggc gttcatccac tcagtattac atccaccagc tcttaagaaa aatgattcgc
    34981 ctgtatgggc atcaacagct ccataacaat agcgaaattc tcgtatatag tgactatgga
    35041 catgtggacc tactcctatt ggagaccaac aagatcccag tttactgatt ctaccgaaac
    35101 cagcctcatc ttggtacatc gagcgaacct tatgaaaacg tctactggtt ttaaagcgct
    35161 ttcttttctt cttgaattga gattttattt ttagacgcga caatggtttg agcgtctgct
    35221 ttcttaggat gttctggacg tggcataata tttcgccaac catggcgctt caacagttga
    35281 tagaaggcat cacgtgtgta ggaacgatat aagcctgaaa taaggtattg taacaaattc
    35341 tcctgcctct gtagccttca aatggcgggc aagaaaggct ttctcttcct caactgtcat
    35401 atatgcatgg ttacgaccac cacgtgtttc ttgaaggaga gagtcgagtc cgaactcctc
    35461 atattttttt acatttcgcc aaatcgttgt ttgattacag tctaaaagct ctataatctc
    35521 tttataagat ttgcccatca gacgaaatag aacgatttga aggcgtttat gatatttagc
    35581 tgtacgagag tcttttaaaa gtgttttgat ggtttggatt tcttctttag ttgatttcat
    35641 attactattg tataatgctt tttgatttga gtctagtatt atactcttcg aaaatctctt
    35701 caaaccgcgt cagcttcgcc ttgtcgtata gatgttactg acttcgtcag ttctatctac
    35761 aacctaaaaa cagtgttttg agcagtctgc agctaacttt ctataacaaa atgaaataag
    35821 aacaagacaa atcaatcaag ataatcaaat cgatttctaa caatgtttta gaagtagatg
    35881 tgtactattc tagtttcaat atattatagt ttgctctttg attttcattg agtattagtt
    35941 caatatctaa aaaaagaacc ttgccaagca agattctttt agtgtctgac ttaaataatt
    36001 gttcttctgg gaactaaatc gaattaagct tcgatttctg taaccatacc tgaaccaaca
    36061 gtacgtccac cctcacggat agagaatgta gtaccttgtt ctacggcgat tgggtgaatc
    36121 aactcaacgt cgattgtcac gttatcacca ggcattacca tttcagtacc tgctggaagt
    36181 tcgattgaac ctgtaacgtc agtagtacgg aagtagaatt gtggacggta gttgttgaag
    36241 aatggagtgt gacgtccacc ttcttcttta gtaaggatgt agacttcacc tttgaattta
    36301 gtgtgtgggt tgattgaacc tggtttagcg ataacttgtc cacgttcgat ttcatcacgt
    36361 tgaacaccac gaagaaggac acctacgtta tctccagcaa gaccttcgtc aagttgttta
    36421 cggaacattt caacaccagt aacaactgct ttttgagttt cttctttgat accaacaatt
    36481 tcgatttcgt cgttgacttt aacgatacca cggtcgatac gtcctgaagc aactgtacca
    36541 cgtccagtga ttgagaatac gtcctcgact ggaagaagca atggtttgtc agtgtcacgt
    36601 tctggttctg ggatatactc atcaactgtg ttcatcaatt ccataacgat gtcttcgtat
    36661 ttagagtcac cttcaagagc tttaagtgct gaaccttgga taactggaag atcgtcacct
    36721 gggaagtcgt attctgacaa taggtcacgg atttccattt caaccaattc aagcaattct
    36781 tcgtcgtcaa ccaagtcaac tttgttcatg aagacgataa ggtgtttaac accaacctga
    36841 cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc cgtcagttga agctactaca
    36901 aggatagctc cgtccatttg agcagcacca gtgatcatgt ttttaacgta gtccgcgtgt
    36961 cctggagcgt cgatgtgagc gtagtgacgt ttttcagttt cgtactcaac gtgcgcagtg
    37021 ttgatagtga taccgcgttc gcgttcttct ggagcagcat cgatagacgc atagtcttta
    37081 ggttggttaa ctgatgaagg caagcgacgt gccaaaacag ttgtgatagc tgcagttagg
    37141 gtagttttac cgtggtcaac gtgtccgata gtaccaatgt taacgtgtgg tttactacga
    37201 tcgtattttt cttttgccat ttgagtaaaa gcctccaata aaatatattt tatagataga
    37261 cagtaggcaa tacagtctaa ctttccttac tattttatca aatttcagct aaattgcaag
    37321 tgttttacaa cgtttttgtg aattattctt ggtaaaaatt taactaatta atagaaagta
    37381 ctaaatagac ttatccttca aggagttttc agcattatcc atccactcac ttgctgaaaa
    37441 tgtaaacagt ctctggttta tatagtaaaa tgaaacaaga atagggcaaa tcgatcagga
    37501 cagtcaaatc gatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc
    37561 tactatacaa cctcaaaact gtgttttgaa caacctgcgg ctagcttctt agtttgccct
    37621 ttgattttca ttgagtataa aattgcagat aaaacgataa caatcatagg actcagcaga
    37681 gtcaatgtag gtcgaagaat agccccctaa tcgcttattt tatagcaaaa tgaaatagaa
    37741 actgaacatt ttgttgagga aggtaaatca attcctcaca atgtttgaga aagaaggggg
    37801 gactattcca acttcaaccc actataaagc agacttacaa gatagggaac ccatctccga
    37861 taatatatag tagaatgaaa actgcacaat ttgattggag aattcaaacc aatttctaac
    37921 aatgttttag aaacaagggt ctattatttc aactgcaacc tactatagcc cattgaagct
    37981 ggaatagccc actgagactt ctaaaccact gctggagagg agtttgttta gagtttcttt
    38041 catttcccta aaaaatcaaa aagagagaac cagtctgatc ctctcttact tatagatggt
    38101 gctcactcaa atgttaaagg agctatttct tagagataaa ggaatttgaa tacagctact
    38161 gccgcaattg ctgctgcgat aggtgctact actggtaccc aagaatacca ccattttgaa
    38221 tcgcctttat gctcaccaag aactgatttt ggaaggaaag catgaaggag acgtggtccc
    38281 aagtcacggg ctgggttcaa ggcaggtcct gtaggtcctc caagtgatgt taccaaagcc
    38341 ataacgagga atccaagtgc caagtgagcc acagaaagtc ctgaagcagt gtgtggagcc
    38401 acctgtgctt taatagccaa gtcagaaaaa tcaactgttt gtcctgcttc tattgccttt
    38461 tgtttcatga attgaagcac ttcagcacca aagaagtttt tagtcaaacc aagagctgca
    38521 aagaacaaaa caaatgaacc aacaaactca ttaatcaaac cattgacagt tgctgcatag
    38581 cgactttctt ttgtaccatg gtcaatactt gaaatagttg agaaagttcc caagatgtta
    38641 tttgggtttt cagttttcaa gtagaatgga cggtatgttg ccacaactaa ggcttggcca
    38701 aagatagccc ccaagacttg cgcgataata taaggtacca cttgtgccca agggaaaaga
    38761 ccgctaactg caagccctag agtgaaagca gggttgatgt gattcccaga tacgttacca
    38821 aacatcaagg cagggatcat aacccccata ccataaccaa cagcgatgac gatccagcca
    38881 ctttggtgac ctttcgtacc tttaagttca acgttggcaa ctgcaccatt cccaagaatg
    38941 atcaaaatgg cagttcccaa aaattcagtg gcatacttca gtgcccatgt gaaatccatt
    39001 tgctagattc tccttaaaat tttttagata ttccttattt tatcaatttt taccctattt
    39061 agcaactgat ttctggaaat atttttaaaa aaataggatt catagtttcc cagttcaacg
    39121 aacttgtaag cgtttttatt cttcacgaaa gacctcgttc tcaaaaccag gaaaaaagcc
    39181 cacatctgtg agcttttcct ggttcctaga ttctaaaatc tattattttt catcttcttt
    39241 tttcttgaag aatcctaatc ctagactagc taacaaggtc atgataccag cactagccaa
    39301 ggtagcatta gcttctgtac ctgtgtttgg caattcctct ctcttacctg tctcataagt
    39361 cggaacttct gggtctggat tcactggagt ttcagttttt ggagtacctg ggtctggagt
    39421 tggtttatct ggtgttgata aacggtcata ccttaccgtt atttctttat cactagagtc
    39481 tgacgtaact tcttgtgatt caactgttgg aatatctgga tctttgtact tgtcaatctt
    39541 accagataca acctcgtccc agtttcctgt tgtccattca ccgtaggtta caactcccgt
    39601 gaccttgttc tcagtttttg tacggcttaa ggttacaggt tgaacaacat cttcttttac
    39661 attttggttc gtaactttat caacgtaatg aatgatacgc gttatagtct tcgtctcagt
    39721 agaggttgct gttttgggaa ccactgtttc ctcaacattc tcacggtagt aatagtcaac
    39781 tgttgcaccg tcttctggta cgcatttgca ggagttgcta ccaaggtgta tgttgttttc
    39841 cttgtgataa ctcggtcttc tttgtcctca gttgttgttt tcccttcaat agtttttgat
    39901 tctgtggtat actcagaacc tatcgctaaa tcagctttta taacagactc tgccaacttc
    39961 tcttggctac cttctttata gtaattggct gttactgtag cagtggttgg cgcttcgctt
    40021 tctctataaa ctaaggtcac tgttctacct tcgcttacaa tattcccagt taaacttgca
    40081 gaatttgtat ctgcttcttt aaaagtataa tattttccgt cagtagtagt catgctactg
    40141 agttttttat ctgtgacatt gtagctggta ccaatcagtt gttttttatt ggtaatgtag
    40201 gttccgtcac tttctttttc tccaattcca gtatcatttt tcaatgatag caaacgccct
    40261 tgttcatcaa catagcgaac tttcacattt tctgagatta gttctgccaa ttctgaggtt
    40321 tttttctttt tcttgatttc ttcggttatt ttccctttct cttcttcggg aatatttagt
    40381 tttggaatga ttttttcaac aacggttcgt gatggttcca cagtatcttg gatgactgaa
    40441 aagtcagcta gaattgggag attatactga acacggtgac tttgagtgtt tactcctact
    40501 ctttcattat tctctgaaaa tacttgtacg gtataagaaa caacaacaat tataggcgat
    40561 acgataattt acactgtttc acaatacgtt gaaatttaga gctttaaagc gagggcaaag
    40621 ttgatttttt acatcgtttt acagaggttt acgacacttt tgcccctttt ttgccccttt
    40681 tgagcaaata aaaaaccgca agcctgagcc tgcggtgaaa gaacaattta gaaagtttcc
    40741 tttctattta tttaactgta atcaagccat ctggctctac tgtgaagtct ggcttatctg
    40801 ccagtgttcc gtctggtttg aggtagtacc agcctgttcc gtctgcggac tggacgaagg
    40861 cgtttgatac catagcgcct tctttagcgt ctaagtagta ccaagtgttc ttgtacttga
    40921 cccagcctgt cttcatggca ccttctacat caaaatagta ccacttctca gcgattttct
    40981 tccagcctgt ggccatttcg cctgagttgt cgaaccagta ccaattaccg tctgtgtgct
    41041 tcttccagcg gtctgaaagc atatagcctg agccatcgaa ataataccag gtaccgttga
    41101 ttttctcaaa cttatctttt ggataagagc cgtctgagtg tacgtaccag tagccagtgc
    41161 catttttctg ccagcctgtt gcagcgctca agccgttttc gatgtcttgc ttaaactgtt
    41221 cacggctaat gccccaactt gcaagatatg gatatggatc cacatggtct gagtggttgt
    41281 ttggttggtt attggtacag tattcatgcg tcttgatacc tgccaagtcg tctgtatcaa
    41341 gagtcttcgg caagcctgct tcgtccgcta gattgcgtag caattcgata tagaggcgat
    41401 agtcagccat aaactcttcc ttagttgaat ggctttcaat cagttcaacc gctgcataag
    41461 tctcagcatt ccaaccgccc ccaacatccc aacttccgtt gttcacaggt cctacctgca
    41521 tgatgcggcc atttccgaca acgtgcgaga aaaaacctaa ttctgggtct ttccgccagt
    41581 gataatccgc ttcattctgt acggttgagt tgcggttgcc tgttgagtga gcatgtactt
    41641 gtcgataagg ctgcacccca acctgtggca agcctgtacg tagtctgttt ctatcgatat
    41701 ccattcccta tcgtcctttc catgcgtcat tcatctgctt cactgctgac tctacgaagg
    41761 tgtctaagtc tttgtcagtc atgctaatat tgtattttgt aagctcagca cggactttag
    41821 cacgagcctg tgccagtttt tcatctccct tgtagccagt ttcagcagct acctgctcca
    41881 cggcatttac tgcatttttg gccaagattt caacgatttt gatggtcttt tctccacctt
    41941 tttgaaccag gtagtccttg actgccctaa ctaccacccc tgccaaaatg actaggatgc
    42001 tgattgctcc attagtaatg atttcagtaa tttgttgcat ttgttattct ccttttttcg
    42061 tgtcatcatc tttttcaagt aatcgctgaa atacttttac aatcggctga aaaagagtaa
    42121 catttccttt taatttgcgg taattttcaa tgagagattg aaaagtaaat gcgatgtacc
    42181 cgagatagat tgagtgcaag aatacaaaac ctgtcttttc aggcaacaaa acggacgccg
    42241 gaatgaggat catcagtaag agaacccctg aaatcttacg aaggagcccg ttaatgccga
    42301 ttttgctctt gtactcgatg tcaggattga taatcgccgc aatcgtccct gtgacaaaat
    42361 caatgatttc cattgagaca atcagtgtta gagcgtacaa gaccaaacca tcttcagtct
    42421 gtacgacact tcttagaaaa ttgaaaaatt caattttcat acacacctcc tattccttat
    42481 gctcagaatc tgcttccagc tctgccaaaa tggcatcttc aatcttatag cgcatttctc
    42541 gtaactcttg ctcatgctta cgcatactga tacgattgtt agcgtacagt tccgggtcat
    42601 gcagcgtttc agatattgtt gaaacagctt tattgtctgt gttgattaca gtagttttga
    42661 ccaatttttg ttggtcgcca tcttgtgcga aaaattcagt tactagctga cgtgttttag
    42721 tgacttttaa cattgtcatt tcctccttta taaattaatt atccgttaat aattagggat
    42781 tttttacggt tgttatattt tgaaaaacac attatcaaaa ttaagccaag tagcatctac
    42841 attagatttg acaactacgt ttccatttgg ataaattcct ataacggctg aaccgtaatc
    42901 attattcaaa gcagttttga ataatgttgt agatggtctg aaatgttcag gtaaagtaag
    42961 tatgattgac tcacgtgcaa tctttccgcc cttacatgtt cctttaaaac aaacaacacc
    43021 atcgaatgtt tttgaaaatt ggacacctcc gtaatccctg tgatgattcc atccattttg
    43081 taaaatggca ttttgccaag gagtcggagt gctttctgat tttagcaaag ctacatagtc
    43141 agagttatta gtagacttgg attgttgcac cagatagcgc catggtctcc agttgttatc
    43201 ataaccattc tccctaactg ccatatatcc tgttgaggta gtgaagcgtt gaatacgttc
    43261 atgagagcct ggattaggtc tgaatacctc tagcatcccc caagttccag aaaaggggtt
    43321 gttttgagag ctaccattta tccaccacgt tccagtctct ttcatcgtat taaaatcctg
    43381 tttgataagt tttccacatc cattattgtc agtcaattga tattgttgaa taggtttatt
    43441 tctagcgtag atatctccca agacatccaa tgaccctgca ccagccttac ctgccacgcc
    43501 atttgcgcca tcacgacctt tccatcttgt ccagcgataa tcagcaggat ttctgctgtc
    43561 tgttggatta aaatcaatgt acactccaac aaaggctttg tcagtgtttg tttgactgaa
    43621 tccaccacct gttgcgttat cggcataggc catgtgagta tattgtgtac gaccatctgc
    43681 ccctctaggt ccaggaatac cttgttcacc tcgtgcgcct tgcaagcctt gtaaaccttg
    43741 taatccacgt tctcctttat cgcctttttc tcccttgtcc ccttttactt tagcccactt
    43801 gtatttttta gggtcggtac tatctgcctg agtgtaatct gtgtatgttc cgatatacgt
    43861 tttatttgta ctgtcagtag ttgagaagcc ttgtgagccg ttatttgatg tggcgtaagc
    43921 tatgtgtaag tatggtgtcc taccatctgc accagcccta cctgccacgc cgtttgcgcc
    43981 atcacgacct ttccatcttg tccagcgata atcagcagga tttctgctgt ctgttggatt
    44041 aaa
//
LOCUS       DAVKZI010000013        42942 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKZI010000013 DAVKZI010000000
VERSION     DAVKZI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.013"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(346..738)
                     /gene="rpsI"
                     /locus_tag="VXB18_000834"
     CDS             complement(346..738)
                     /gene="rpsI"
                     /locus_tag="VXB18_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0382061.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(757..1203)
                     /gene="rplM"
                     /locus_tag="VXB18_000835"
     CDS             complement(757..1203)
                     /gene="rplM"
                     /locus_tag="VXB18_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0382062.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1559..1876
                     /locus_tag="VXB18_000836"
     CDS             1559..1876
                     /locus_tag="VXB18_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0382063.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(1921..2733)
                     /gene="folK"
                     /locus_tag="VXB18_000837"
     CDS             complement(1921..2733)
                     /gene="folK"
                     /locus_tag="VXB18_000837"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0382064.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVEHTFETYPLVQEMKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2892..3446)
                     /gene="folE"
                     /locus_tag="VXB18_000838"
     CDS             complement(2892..3446)
                     /gene="folE"
                     /locus_tag="VXB18_000838"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0382065.1"
                     /translation="MDKQKIEAAVKMIIEAVGEDSNREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3439..4749)
                     /locus_tag="VXB18_000839"
     CDS             complement(3439..4749)
                     /locus_tag="VXB18_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0382066.1"
                     /translation="MKEFENNQWITNYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     QSLLEGESAANLQGTTEFEIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAVAEQKAGIIKQGIPSVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGADYQVSHQESVVTGEVFDYTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     DGRKLASNHLLAQALEETSWPGRLEIVSRDPLMILDGAHNPHAIRALLATLQERFADY
                     HKEILFTCIKTKALEDMLNLLEQIPDTEVTLTHFDDSRATDESVLKEAAQSRNLSYQG
                     WQDFLEQKLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENG"
     gene            complement(4751..5728)
                     /gene="folP"
                     /locus_tag="VXB18_000840"
     CDS             complement(4751..5728)
                     /gene="folP"
                     /locus_tag="VXB18_000840"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0382067.1"
                     /translation="MMKSLEGVTDMSSKANHVKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYYVEIEEEIQRVVPVIKAIRKESNVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKARAKVVIMFNPVMARPQHPSSL
                     IFPHFGFGQTFTEKELADFETLPIEDLMEAFFDRALSKADEAGIAPENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETEHGFRNRDTA
                     SAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5824..6531)
                     /locus_tag="VXB18_000841"
     CDS             complement(5824..6531)
                     /locus_tag="VXB18_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0382068.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILILKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIIPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6585..8003)
                     /locus_tag="VXB18_000842"
     CDS             complement(6585..8003)
                     /locus_tag="VXB18_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0382069.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALIVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            8193..9005
                     /locus_tag="VXB18_000843"
     CDS             8193..9005
                     /locus_tag="VXB18_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0382070.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKNIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9344..10363
                     /gene="adhP"
                     /locus_tag="VXB18_000844"
     CDS             9344..10363
                     /gene="adhP"
                     /locus_tag="VXB18_000844"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0382071.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10596..11585
                     /gene="manX"
                     /locus_tag="VXB18_000845"
     CDS             10596..11585
                     /gene="manX"
                     /locus_tag="VXB18_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0382072.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11613..12416
                     /locus_tag="VXB18_000846"
     CDS             11613..12416
                     /locus_tag="VXB18_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0382073.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12440..13351
                     /locus_tag="VXB18_000847"
     CDS             12440..13351
                     /locus_tag="VXB18_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0382074.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13407..14741)
                     /gene="pepC"
                     /locus_tag="VXB18_000848"
     CDS             complement(13407..14741)
                     /gene="pepC"
                     /locus_tag="VXB18_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0382075.1"
                     /translation="MNAIQESFTNKLFANYEANVKYKAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(14958..15680)
                     /locus_tag="VXB18_000849"
     CDS             complement(14958..15680)
                     /locus_tag="VXB18_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0382076.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(15903..16133)
                     /locus_tag="VXB18_000850"
     CDS             complement(15903..16133)
                     /locus_tag="VXB18_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0382077.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(16143..17384)
                     /locus_tag="VXB18_000851"
     CDS             complement(16143..17384)
                     /locus_tag="VXB18_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0382078.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKANMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(17406..17558)
                     /locus_tag="VXB18_000852"
     CDS             complement(17406..17558)
                     /locus_tag="VXB18_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382079.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            complement(17579..17857)
                     /locus_tag="VXB18_000853"
     CDS             complement(17579..17857)
                     /locus_tag="VXB18_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0382080.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(17850..18113)
                     /locus_tag="VXB18_000854"
     CDS             complement(17850..18113)
                     /locus_tag="VXB18_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0382081.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(18215..22606)
                     /locus_tag="VXB18_000855"
     CDS             complement(18215..22606)
                     /locus_tag="VXB18_000855"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0382082.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFQTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPQVEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(22710..24791)
                     /gene="fusA"
                     /locus_tag="VXB18_000856"
     CDS             complement(22710..24791)
                     /gene="fusA"
                     /locus_tag="VXB18_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0382083.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(25216..25686)
                     /gene="rpsG"
                     /locus_tag="VXB18_000857"
     CDS             complement(25216..25686)
                     /gene="rpsG"
                     /locus_tag="VXB18_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0382084.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(25706..26119)
                     /gene="rpsL"
                     /locus_tag="VXB18_000858"
     CDS             complement(25706..26119)
                     /gene="rpsL"
                     /locus_tag="VXB18_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0382085.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            26536..30333
                     /gene="spuA"
                     /locus_tag="VXB18_000859"
     CDS             26536..30333
                     /gene="spuA"
                     /locus_tag="VXB18_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0382086.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSILIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNDVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(30433..31482)
                     /locus_tag="VXB18_000860"
     CDS             complement(30433..31482)
                     /locus_tag="VXB18_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0382087.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            31539..31616
                     /locus_tag="VXB18_000861"
                     /pseudo
     CDS             31539..31616
                     /locus_tag="VXB18_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(31753..33561)
                     /gene="glmS"
                     /locus_tag="VXB18_000862"
     CDS             complement(31753..33561)
                     /gene="glmS"
                     /locus_tag="VXB18_000862"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0382088.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKEVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSKTERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQVFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(33731..35110)
                     /gene="bglA"
                     /locus_tag="VXB18_000863"
     CDS             complement(33731..35110)
                     /gene="bglA"
                     /locus_tag="VXB18_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0382089.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(35210..37063)
                     /locus_tag="VXB18_000864"
     CDS             complement(35210..37063)
                     /locus_tag="VXB18_000864"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0382090.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(37076..38335)
                     /gene="rseP"
                     /locus_tag="VXB18_000865"
     CDS             complement(37076..38335)
                     /gene="rseP"
                     /locus_tag="VXB18_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0382091.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(38357..39160)
                     /locus_tag="VXB18_000866"
     CDS             complement(38357..39160)
                     /locus_tag="VXB18_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0382092.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(39169..39927)
                     /locus_tag="VXB18_000867"
     CDS             complement(39169..39927)
                     /locus_tag="VXB18_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0382093.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDCLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(40158..40730)
                     /locus_tag="VXB18_000868"
     CDS             complement(40158..40730)
                     /locus_tag="VXB18_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0382094.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIGVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(40711..41682)
                     /gene="ruvB"
                     /locus_tag="VXB18_000869"
     CDS             complement(40711..41682)
                     /gene="ruvB"
                     /locus_tag="VXB18_000869"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0382095.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            41842..41934
                     /locus_tag="VXB18_000870"
     CDS             41842..41934
                     /locus_tag="VXB18_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0382096.1"
                     /translation="MMELVLKTIIEPIVVGVVLRLVDKWLNKDK"
     gene            42275..42367
                     /locus_tag="VXB18_000871"
     CDS             42275..42367
                     /locus_tag="VXB18_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0382097.1"
                     /translation="MMELILKTIIGPIVVGVILRLVDKWLNKDR"
BASE COUNT        12517 a         9907 c         8284 g        12234 t
ORIGIN      
        1 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga attcgatttg
       61 actatcctcg gtttgtccta ttcttatttc accttactat aaaaataagg taaacttttc
      121 aaaaaaacac gaaaaaagca cccatagggc aaacctttga gtgctttgaa acattgatat
      181 aattgtattg attagcgttt tgaggcaact gaccttgtca ggttgcagcc acatttgtaa
      241 gcgactaaag tcgcaacaac tgtgtcaatt gcaccaattt agtaagaaag tataaaaaag
      301 aacaccccga aaggtgctct gtataagtat agtaattctt tcgaattaac gtttactaaa
      361 ttgtgatgct ttacgagctt tcttaagacc tggtttctta cgttcaactt tacgtgagtc
      421 acgtgtaaga agtcctgcgc gtttcaatga atcgcggaag tctgggtcta cttgaagaag
      481 ggcacgagcg ataccgtgac ggatagctcc tgattgacca gcgtatccac cacctacaac
      541 gttaacgaaa acgtcgtatg aacctacagt tgaagtaact gcaaatggtt ggttgatgac
      601 aagacgaagg tcagcgtgtg ggatgtactc ttcaacatct tttttgttaa cagtgatttt
      661 accagttcct ggaacaaggc gaacgcgtgc aacagcgttt ttacgacgtc cagtacctgc
      721 atattgtgct tgtgacatac tttattgttc ctttccttag ataagtcctg aaatgtcaag
      781 aacttctggt tgttgtgcag cgtgagtgtg ctcggctcca acaaatactt tcaacttcat
      841 accttgagcg cgtccaagag tattgtgtgg aagcatacct ttaactgatt tctcgatcaa
      901 acgtactgca tttttagaac gaagttcacc tgcagagatt tgtttcaatc cacctgggtg
      961 gtttgagtga gtgtagtaga ttttatcagt tgctttttta ccagtcaatt taactttttc
     1021 agcattgata acaatcacga agtcacctgt atcagtgtgt ggtgtaaatg ttggtttgtt
     1081 ttttccgcga agtacgctag caactactgc agaaagacgt ccaagtggta catcagttgc
     1141 gtcaactacg taccatttac gttcaacttg gcctggttta gccataaatg ttgttttgtt
     1201 catgatttct cctatatata gttcgatttt tgtttacggt gatgggtgtt ccttcccatc
     1261 gaaaagtatt tggaaggttc cggggccttt caaatggggt aaacaatacc gcctactatc
     1321 ataccaaatt tcacccctaa aagtcaatag atataaaaaa tatttttcgg taacttctca
     1381 aaataactga aagttatata atcaagttaa tttgggaatt tacctattaa cttcggtaga
     1441 tttttgggaa ttttttccct atttctccct gtaactaaaa tccttttcaa aaaatcacct
     1501 tttcttgatt tttaatccta tttgctgtat gataagggaa aagaaagggg acagagatat
     1561 ggcttttacc aatacccaca tgcggtctgc tagttttggc attgttacca gcttgcccga
     1621 tgacatcatt gactcttttt ggtatatcat cgatcatttc ttaaaaaatg tctttgaatt
     1681 ggaagaagaa ctcgagtttc aattgcttaa taaccaagga aagattacct tccacttttc
     1741 aagtcaacac ctccctacag ccattgattt tgactttaac catcctttcg accctcgtta
     1801 tcccccaaga gtactggttt tagacatgga cggtagagaa actatcctcc tcccagaaga
     1861 aaatgaccta ttttaaaaac tctagccttc agttgcaagt aactgaaaac tagagttttt
     1921 ctattttttc aaagcatcat acaagttgcg gatcggttgt tttaatatcg gatggataaa
     1981 atgaggcgca atttcctgta aggactcaag gacaaaaagg cgttccgcta tgtaaggatg
     2041 aggcaatatg aggtcgtctg tataaaggat ctggtcctcc acaaagagca agtccaaatc
     2101 aatcaaacga ggtccccaat gcacttctct cacccgtccc agctctgact caatggctaa
     2161 caaggtttct aacaagtctt gtgctggtag ccaggtttcc acctcaacca cttgattggc
     2221 aaagctatcc tgctccactc caccccaagg ctccgtcgct aagacactgg actctttgag
     2281 aatatggata cctcgatttc gcattttctc aatggcttgt ttcaagtttg cttgtttatc
     2341 tcccatattg cttcctaggg cgataaaggc tcgttgctta cggcgatgga tggttacgga
     2401 gcaagtatct aacggcaaat gcactggcgc ccaaggtttt ttcagttcca gcttcatttc
     2461 ttggacaaga ggataggtct caaaggtatg ttctaccagt ttgtaggcta ccgtttcaat
     2521 caaatcttca ctcgtttcct gaaaccaagt cgtccactgc tgacacaatt ctccgtaatg
     2581 gacagaggct gttaaatcca agtctgtagc tgccttggtc atatcatagg ataggatggc
     2641 tgaaacgaca aatttctgcc ccaattcttt ctcactagga aaaagaccat gataggcaaa
     2701 catttccaaa tccttaatct gcagttgatc cataatgatt cctttctcga aaaatccgcc
     2761 caaagcggat tctttttata ctcaatgaaa atcaaagtgc aaactaagaa gctagccgca
     2821 ggctactcaa aacactgttt tgaggttgca gatggaagct gacgtggttt gaatttgatt
     2881 ttcgaagagt attatagtcc cattaaacga taagcctgat ctcggaggtc cttatctgtt
     2941 tcaaatagac cacgagctac tgtcgtcaag gttgcagtgc ctggttttct gacaccacgc
     3001 atactcatac acatatgttc cgcctcaatg acaacaaagg ctcctttagc gcctagatag
     3061 tccatcaagg catcggccac ttcgatattc aaacgttctt gaatttgtgg ttttttcgaa
     3121 taaacttcaa ccgtacgggc tagcttagat aaacctgcta cacggccatc tggaatatag
     3181 gcaatatgcg ctctaccata aaatggcaag aagtggtgtt cacacatggt atggaaaaag
     3241 atatcctttt ctaccaccat attatcgtca ataatctcaa aagattttga caaatgttcc
     3301 tccgctgttt gaccaagacc tgaaaaaatc tcttggtaca tacgagccac acgagcaggt
     3361 gtttcctgca agccctcgcg gttagagtcc tctcccacag cctcgataat catttttaca
     3421 gctgcttcaa tcttttgttt atccattctc gttcttcctc tccatcagat aggctctcac
     3481 ttggctcaag aaatacaagg aacctgtgac aatcctaact gtttgtttct cttctttttt
     3541 atctgtcaat ttctgctcta gaaaatcctg ccaaccttgg tagctgagat ttctagactg
     3601 agctgcctct ttcagcacgc tttcatcagt cgcccgacta tcgtcaaaat gtgtcagggt
     3661 aacctcggta tctgggattt gctccaacaa attcaacata tcctccaagg ccttggtttt
     3721 gatgcaagta aagaggattt ccttatgata atccgcaaag cgttcttgca aggttgccaa
     3781 taaagccctg atagcatggg gattgtgggc cccatccaaa atcatcaagg gatctcttga
     3841 cacgatttcc aaacgccctg gccaacttgt ttcttccaag gcctgagcaa gcaagtgatt
     3901 gcttgctagt tttcgcccat cttcttgaca aaaagtatca agtaaagcta tggccatccc
     3961 agcattctct atctggtgca aaccaagcag gccagtctgg aagcgacctt gtctgacaac
     4021 acttgtatag tcaaagactt cacctgttac cacactctct tggtgactaa cttgataatc
     4081 tgccccgtag gcaagtctcg gcgcatcttt cccttccgca atgcggtcaa taacagccaa
     4141 ggcttctgga gcaatgcgac ctgtcaccga gggaatgcct tgcttaataa taccagcctt
     4201 ctgctctgct acggcttcca aggtgtcacc aagtagggct acatgatcca gtccaatggt
     4261 cgtgatgcct gttagaatgg gctggcagac attggtacta tccaagagcc cacccatgcc
     4321 aacttccata atagccacat ctacttgctc tgaggcaaag taatcatagg ctatagctgt
     4381 aattatctca aactcagttg tcccctgcaa attagcagcc gattccccct caagcagcga
     4441 ctgatagtct gccatgagag cttctagtct agcttctggg atagattccc cattgatgct
     4501 aatctggtct gtgtaatgaa tgagataggg cgagctaaac acgccaactc tcagccctag
     4561 tttttctagc atatttttca aaaaagcaat ggtcgaaccc ttgccattag ttcctccaat
     4621 atggatgacc ttgagtttga gatggggatt gccacgcaaa gctaacagtt ccaccattcg
     4681 ttccaagcca aaatgcggtt ggtccgtccg gtaattggta atccactgat tgttttcaaa
     4741 ttctttcatc ttatttgtat tgttttaaat ctaaattttc cgcttcatca gccagacgaa
     4801 tagcggaggc aatttcaact gccatcctgt gactagctac gtcatgcacg cgcaccactt
     4861 ctacaccctg tctcgcagcg atactagtta catgagccga agctgtgtcc cgattgcgga
     4921 aaccatgttc tgtctcagga ttgacttcaa acccactttc ttcaaggata ttgatgacaa
     4981 atcgcttgcg cgaaactccg agaaagattg gatagccttt ctgatggagt ttatccagat
     5041 cccgtaaaag aagcagattt tctttcttag tcagaccaaa gccaattcct ggatccagca
     5101 ggatattttc tggtgcaata ccagcttcgt ccgctttcga tagggctctg tcaaagaaag
     5161 cctccatcaa gtcttcgatt ggcaatgttt caaagtcagc taactctttt tctgtaaagg
     5221 tttgaccaaa gccaaaatga gggaagataa gcgaactagg atgctgaggt cgagccataa
     5281 ctggattaaa catgatgacc actttcgctc tcgctttagc taccacatga gccatttttt
     5341 catcacccat gagaccagtg atatcattaa ctagattagc accagcagcc aaagcagctt
     5401 ctgctacctg actcttccaa gtatcaatag agatgaggac attactttcc ttgcgaatcg
     5461 ctttgatcac tggaacaaca cgctggattt cctcttctat ctcaacataa tagctactgc
     5521 ccggccgagt cgattctccg ccgatatcta gcatactggc tccttctgct atcaatttac
     5581 gagcctgctg gagtgcctgc tcaagagcaa aaaattgacc accgtccgaa aaggagtctg
     5641 gggttacatt gataattccg caaatagctg tctttacatg attggcttta cttgacatat
     5701 cggtcactcc ctcaaggctt ttcatcatat tatttctcta ttttaccata aaaagaaaaa
     5761 gatggccacg attgcattca tctttttccc agtagaaaga ggtcggttcc tacataaaaa
     5821 cttttaaaca gaaattccta atgtccgact cataatcacc acaagagcca acaaacagaa
     5881 agcaatccca ttaacaatca tgtgaagcaa gatcgacatt tccaaacgtt gggtcttgta
     5941 ggctgtccaa gatagaactg tcgacatacc tccataaatc aataaagaag gtaaattact
     6001 tggttgatgc aataaagcaa acacaatcgt accgactaca aatcccaagt tctccttgcc
     6061 tcggaaaatc tttttaggaa taatcccacg acacaagatt tcctcacaaa tcggagcaag
     6121 caaggctagc aagaagaaac tggaaatcaa cgaactattt tgaaccatat cattaatctg
     6181 agactggtta gctgttgtcg tctcatttga cagttgcaat aaaatggaac caagtatatt
     6241 tgacccgaca ataactagat aactcaagcc caaacgtgcc aaatctttag ctctaaaaaa
     6301 agaaaaatta aaactagcta acttggtttt acgagctccc ataataaata gagccagaac
     6361 cacaattgaa aggccagcaa ctatcagccc tgactgtagc agggctactt cttttaaaat
     6421 caaaatagag gtaaccacta ggggaacctg atataaaagg acggcaagta aaaagaccaa
     6481 aatccagcct gcacgattca acaattcttt ccacatattt ttctctttca tcacctatct
     6541 ccttttgtat taaaaaaggg gggaaatccc cctgggtcat tctattataa ggccatgctg
     6601 atgtagttaa ggataaacaa ggcatccaaa atccaaatca tgacatgaac atctttaact
     6661 tgacctttaa caagcttagt caaagtgtaa gtcaagaaac caactgcaat cccttgagtg
     6721 atagagtagc tgaatcccat aaagatagat gtgaagaagg caggaactgc ttcagacata
     6781 tcatcccaat ggatattttt caagctacca agcatcataa tcccaacgat aatcaagatt
     6841 ggagctgtag ccgctgttgg tacgatcgct agaagtgggc taaagaagct tgaaatcgca
     6901 aaacagatag ctacaatcaa ggctgtcaaa ccagtacgtc cacctgcacc gataccagca
     6961 gcagactcaa cataagtcgt tacgtttgaa gtacctgcaa tggcaccgac tgtcgttcca
     7021 atcaaatcag agtaaagagc cttatccaat ttggctgatt ggtgattttc accatttgtc
     7081 gctacgatac caactttttc acctgtaccg atcaaggtac caattgtgtc aaaaatatct
     7141 gtcaatgaga aggcaagaat ggccatcaga gtttcaggca agcgagctgt atctgaaacc
     7201 aaagctccta aaccttctga accaagagct gcaccaaaga ttgtcttcaa atcttcaaaa
     7261 gctgcaccaa catggttatt agcaaaatcg atactagaca aatcaaccaa accaactgca
     7321 atagcaagaa cagttgttgt caagatagag agaataattc cccctttaat ccctttgatg
     7381 acaaagaaga tagtaatggc aagtcctgca agagccacta aaacagctgg attattaaag
     7441 ctgaccaatc ctggaactgc tgaagagttt gctgcaatcg ttgcttgagc tttgtcagcc
     7501 ccttctccta caacagtata gttgcctgga tcaatcgtga atttcaaaag tccagcattc
     7561 ttaatcccta cataggcaag gaagacaccg ataccagctg aaatagctga gcgaagagca
     7621 ttgggaatcg attcaatgat cattttacga acatttgtca aggtaataat caatgaaata
     7681 atcccacaga tgaagaccat agctagggct tcttgccaag aataaccaag cccgaataca
     7741 actgtaaagg taaagaaggc attgagtccc atacctggcg cttgggcata aggtaagtta
     7801 gcataaaaag ccatcatcaa ggtacccgct actgcaccaa taatcgtcgc taggaagacg
     7861 ccctgagcag gcattcctgt ttgtgaaagt atttgtgggt ttacaaagag aatatagctc
     7921 attgcaaaga aagttgttaa accagcgaga acctctgtac gaacgtctgt accgttctct
     7981 tttagtttaa ataatttgtc catcatcaat ctccttttaa tttttacgaa caataataga
     8041 attatatcat ttatcattca ctttttcaat gtctttgttt gatttgttta agaaattaat
     8101 ccaatttcat tttttgtttg gaatctgctt ttctgcctgc tttctgttat aatagaagac
     8161 atcttatctg aaaacacact agaaaggtcc atatgacgaa aaaaattatt gcagttgacc
     8221 tggatggaac cctgctcaac tcagacagtc aaatttctga ctttaccaaa aaaaacatca
     8281 aaaaagttgc tgaaaaaggc catcaggtta ttattacgac aggtcgccct taccgtatgt
     8341 caaaagattt ttaccgtgaa ctgggcttag acactcctat gattaacttc aacggatccc
     8401 ttactcattt accagaccaa gtttgggatt ttgaaaagtg tttgactgta gacaaaaaat
     8461 atctgctaga tatggttcaa cgttcagagg acattcaagc cgattttatc gctggagaat
     8521 atcgtaaaaa attctacatt acaaatccca atgaagaaat tgccaatccc aaactatttg
     8581 gtgtagaagc tttccagcct gaagatcaat tccagcctga attggtgacc aaggacccta
     8641 actgtatcct cttgcagacc agagccagtg acaaatatgc cttggcaaaa gacatgaacg
     8701 ccttctacca gcatcaactt tctatcaata cctggggagg tccgctcaat atccttgaat
     8761 gtaccccaaa aggtgtcaac aaggcctttg ctttggacta cttgctcaag ataatgaatc
     8821 gtgacaaaaa agatttgatt gcctttggag atgaacacaa tgataccgaa atgctcgctt
     8881 ttgctgggaa gggttatgcc atgaaaaatg ccaatccaga gctactccct tatgcagatg
     8941 agcaaatttc ccttaccaac gaccaagatg gggttgccaa aaccctacaa gacttattct
     9001 tataacctat actgatactc aatgagaatc aaagagcaaa ctaggaagct aaccgtaggt
     9061 tgctcaaagc actgctttga ggttgtagat gaagctgacg tggtttgaag agattttcga
     9121 agagtatgac cagcttgcaa gctggtcttt gtgctctttt cacagtctca tcaaccagtt
     9181 aatcgattgt tctacttttt gtctccaaaa ccttggaaaa ggctttcttt tgtgatatac
     9241 ttcacatata aatacaagag agctcgtcac actcgactct gttgacaaaa aatcaatcca
     9301 gtcccgttgt ccctgttctc ggtcaatatc aaggaggata gctatgaaag ctgttgttgt
     9361 aaatccagaa agcactggtg ttgctattga agaaaaagta ctccgtccac ttgaaactgg
     9421 ggaagcactt gtagaagttg aatactgtgg cgtttgccac accgacctcc acgttgctca
     9481 tggtgacttt ggtcaagtcc caggacgtgt tcttgggcac gaaggtatcg gtatcgttaa
     9541 agagattgct ccagatgtga aaagccttaa agtcggtgac cgcgtcagcg ttgcttggtt
     9601 ctttgaagga tgtggcactt gcgaatactg tacaactggt cgcgaaaccc tttgccgtac
     9661 agtgaaaaat gctggctact cagtagacgg tggtatggct gaacaatgta tcgtaactgc
     9721 tgactatgct gtcaaagttc ctgacggact tgatccagcc caagcttctt ctatcacatg
     9781 tgctggagta acaacctata aagctatcaa agaagcaaaa gttgaaccag gccaatgggt
     9841 tgttctttac ggtgctggtg gacttggtaa cctcgctgtt caatacgcta aaaaagtatt
     9901 caatgctcat gttatcgcag tcgatatcaa caatgacaaa cttgcccttg caaaagaagt
     9961 aggcgctgac attgtgatta acggcctcga agttgaagat gtagctggac tcattaaaga
    10021 aaaaactgat ggaggagctc attcagctgt cgtaactgct gtgtctaaag ttgccttcaa
    10081 ccaggctgtt gactccattc gtgctggtgg tcgcgtcgtc gctgttggtc ttccttctga
    10141 aatgatggaa ctcagcatcg ttaaaacagt cctcgatgga atccaagtca tcggttctct
    10201 tgtcggaact cgtaaagact tagaagaagc cttccaattt ggtgcagaag gtctagtagt
    10261 cccagttgtt caaaaacgtc cagtagaaga tgctgttgcc attttcgacg aaatggaaaa
    10321 aggccaaatc caaggacgta tggtactcga cttcacccac taatctaatg gaaacctatt
    10381 ttaaaagttg gaagcttctt ccaacttttt tatattaaat tttaaataag aattcaagat
    10441 tactcctcaa aaactcaaca tatcaacata caaaaataaa aattttttaa ttttttatga
    10501 taaatagttg ctttttttat gaaaacggtt tatacttaaa cagtcttaaa gttttcttaa
    10561 atgaaaacta aaacaaaaaa ggaggaatga caataatgag tatcggaatc attattgcga
    10621 gccacggcga atttgctgcg ggtattcatc agtcaggatc tatgatcttt ggtgaacaag
    10681 aaaaggttca agttgtgacc tttatgccaa atgaaggtcc tgatgatcta tacgctaagt
    10741 ttaataacgc tgttgctgca tttgacgcag aagatgaggt tctagttttg gctgaccttt
    10801 ggagtggttc tccatttaac caagctagtc gcgtgatggg agaaaatcct gagcgtaagt
    10861 ttgccatcat cacaggactt aacttaccga tgttgattca agcctacaca gagcgcctca
    10921 tggacgctgc tgcaggtgta gaaaaagtcg ctgctaatat cattaaagaa gccaaagatg
    10981 gcatcaaagc tcttccagaa gagctaaatc cagtcgaaga agttgcaagc gctgcagctg
    11041 ctccagttgc ccaaactgct atcccagaag gaactgttat cggagacggt aaattgaaaa
    11101 tcaatcttgc ccgtcttgac acacgtctac ttcacggtca ggttgcaact gcttggactc
    11161 cagattcaaa agcaaatcgt atcatcgttg cttcagataa cgtggctaaa gacgaccttc
    11221 gtaaagaatt gattaaacaa gcagctccag gtaatgtcaa ggctaacgtg gttccaattc
    11281 aaaaactgat tgagatttca aaagacccac gttttggaga aacacatgcc cttatcttgt
    11341 ttgaaacacc tcaagatgcc cttcgtgcca tcgaaggcgg cgtgccaatc aagactctta
    11401 atgttggttc tatggctcac tcaacaggta aaacattggt caataccgtt ttgtctatgg
    11461 acaaagaaga cgttgctaca tttgaaaaaa tgcgtgactt gggtgttgaa tttgatgtcc
    11521 gtaaagtacc aaatgattct aaaaaagatt tgtttgactt gattaacaaa gccaatgtca
    11581 aataagccat tatttatgaa aggattttaa acatgtctat tatttctatg gttttagtag
    11641 tcgttgtagc cttctttgca ggtcttgaag gcatcctcga ccagttccaa tttcaccaac
    11701 cacttgtagc ctgtaccctt attgggcttg taacaggtca cttggaagca gggattatcc
    11761 tcggtggatc gcttcaaatg attgcccttg gttggtcaaa tatcggtgct gctatcgctc
    11821 ctgatgctgc acttgcttct gtcgctgctg ccattatcat ggttcttggt ggtgacttta
    11881 ccaagactgg tatcggtgtt gcccaagcgg ttgctatccc tcttgccgta gctggacttt
    11941 tcttgacaat gattgttcgt acaatttcag ttggtttggt tcatactgca gatgctgccg
    12001 ctaaaaaagg tgacttcggc gctgtggagc gtgctcattt cattgcgcta cttttccaag
    12061 gacttcgtat cgcgcttcct gcagctcttc tccttatggt accaactgaa actgtacaaa
    12121 gtatccttag tgccatgcca gactggctca aagatggtat ggctatcggt ggtggtatgg
    12181 tcgttgccgt tggttacgcc atggttatca acatgatggc aactcgtgaa gtatggccat
    12241 tcttcgctct tggtttcgtt ctcgctgctg tgtcagatat tactctaatc ggattcggtg
    12301 ctatcggtgt tgctatcgct cttatctacc ttcacctttc taaaactggt ggaaatggtg
    12361 gcggaggagc cgcaacttct aacgacccaa tcggcgatat cctagaagac tactaagata
    12421 agaaaggact gaaaacatca tgactgaaaa acttcaatta actaaatcag atcgtaaaaa
    12481 agtttggtgg cgttcaacct tcttacaagg gtcttggaac tttgaacgga tgcaaaactt
    12541 gggctgggct tatacactca ttccagctat caaaaaactc tatactaaaa aagaagatca
    12601 aatcgctgct cttgagcgtc accttgagtt cttcaacact catccatacg tagctgctcc
    12661 agtcatgggg gttactcttg cgcttgaaga agaacgtgct aacggtgtgg aaatcgatga
    12721 cgctgctatc caaggggtta aaatcggtat gatgggacct cttgctggta tcggtgaccc
    12781 agtattctgg tttacagtac gcccaatcct tggatctctc ggtgcttcac ttgcccttac
    12841 tggcaatatc ttggggccac tcctcttctt tgttgcatgg aacttgattc gtatgtcatt
    12901 cttgtggtat gttcaagaga ttggatacaa ggctggatca gaaatcacta aagatatgtc
    12961 tggtggtatc cttcaagata tcactaaagg agcttctatc cttgggatgt tcattcttgc
    13021 tgtccttgtt caacgttggg taaatattaa atttgctttc gatgtttcta aagttcaact
    13081 agatgaaaag gcttatatcc attgggataa attgccagaa gggtctaaag gtatccaaga
    13141 agcattcgca caagtaggac aaggattgtc tcaaactcct gaaaaagtta ctactttcca
    13201 acaaaacttg gatatgttga ttcctggatt atcaggacta ctccttactt tactttgcat
    13261 gtacttactt aagaaaaaag tatctccaat cactattatc cttgccctct tcgcagtggg
    13321 tattgtggca catgttcttc acatcatgta atcaagcaac taaaaaggaa ccaggttcta
    13381 aaatctgatt ccttttttct atgcttttat tcagccaagg ctcccattgg atcccatggt
    13441 gcaagtacga ttggttctgc tccataggca gcttgttctt ctgctgtcag caattcctta
    13501 cgaacaacga tttggtatgt gtattcgtcc atccaagcgt ctgaggcaac aaagtaacca
    13561 tctgtaccga ccttgtctcc ccatgagttt tcaaccttcc acttggttga tttaccattt
    13621 tcgtccaagt caacacctgt caagaccatg gcgtgggtca tcaagctttc gctatagtcc
    13681 aaacgtccag ccttgtcttg agtaagttta atgtccatgc ttgattcaaa gtcataaaca
    13741 tctgtcgcaa ggatgccagc cttacggttg ctgagctggc cgacatcaga accaaaccaa
    13801 acagtctcac ctgcttgcat ttgggcaatc gccaattctt tcaagcgctc cattggaacg
    13861 ttgatgtagc gaactgcacg gctaccaaca acattcccca acatctcaac tgtgtaagat
    13921 tttccgtaag gtttatcagc agttggagca ttgataacag aaacgtagtc ttctaaagga
    13981 agattgacat atttcttgta aaactcttgt ggtgtgattc ctttttcact tttgtagttg
    14041 ttatctttat cgcgataagc aaagtcaaac ttgcgtggtg gaagtcctaa tgacatagca
    14101 agaaagttaa agatttcttg caagaggtct tctttcttag tttgaacagt cgcttgatct
    14161 gcaccagaaa caagcaaatc acgcaagatt tgagcatctt gacgaagcaa tttattaagg
    14221 atcgcattta gctcacgact gctgctagat gaaacagact caggataaac tgacttaggc
    14281 acgacaccgt atttttcaaa gagggaaacg accatatccc attgaccgcc atcttgttga
    14341 ggtgtttgga gtaagaagct aaccttgcgg ctagtcaatt cttggtctga agtcgcaatg
    14401 acttgctcca agaaccagtt tgatttctca tacttatccc agaagaaagt gtgggcttgt
    14461 gacaactcaa agttctccaa tttgtattgc gagatgagtt tgtggcggaa ggtgttgaga
    14521 gccgcaaaca tccagcaacg accagacgct ttctggttag tgaccttgtc cttggttaaa
    14581 tccaatgaga aaacaggtgt gttgtctaca tggctttggc gacattccag agctgcaaaa
    14641 attccgttgt ggctggcagc attttcaatc gctttgtatt ttacatttgc ttcatagttg
    14701 gcaaatagtt tattagtaaa tgattcttga atcgcgttca tagattcctc cttttattct
    14761 acagtctatt ataactcttt tcacaaagga agcaactaaa aaacataaaa ggtaaggaca
    14821 ttctccctca cctttttcga atttatactc ttcgaaaatc tcttcaaacc acgtcaacgt
    14881 cgccttgccg tactcaagta cagcctgcgg ctagtttcct agtttgctct ttgattttca
    14941 ttgagtatta aactaaatta aataatatta gcgcggagaa tttctaattc ttccttggtc
    15001 aagcgacgcc attcccctcg ttccaggttc tcatctaata ctaaagttcc catagtcaat
    15061 cgttgcaagt ccaccacttc cttgccacag tagcccacca tacgcttgat ctgatgaaac
    15121 ttcccttctg caatggtcac acggatttgg ctttgattct tttctgtatc tatggataca
    15181 agctccagta tagcgggttg acaggtaaag tctttgagag gaataccctc agcaaatgtc
    15241 tccacatctt cttgggtcat gattcccttg acttgtgcca gataagtctt gtccacatga
    15301 cgcttgggcg aaagaagaac atgagccagc tgaccatcat tggtcaagag caaaagacca
    15361 tgcgtgtcaa tatccaagcg tcctactggg aaaacttcct tactccgcgc caagtcatcc
    15421 aacaagtcca gaacggttct gtgcttggga tcctcagtcg ctgagataac tcctttgggc
    15481 ttgttcatca tgtagtagac aaactcttca tactccaaca cttgcccatc aaagcgaatc
    15541 tcatctattt tttcatcaat ctgcaattta gctgattttt cttttttacc atttacagtc
    15601 acgcgcccag ccttgagcaa gtttttgacc tcagtccgac ttcccaccgc acaggcaact
    15661 aaaaatttat ctaatctcat agaactatta tatcatatca aaaggaggct ggtacaatga
    15721 ccaacctcct tttcgtttca tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct
    15781 tgccgtatat atgttactga cttcgtcagt tctatctgca acctcaaagc agtgctttga
    15841 gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatc agatttagga
    15901 aattaacttc ctcgtctcca aaaaatagct aaaacaatca tggctcctaa aatcgctggg
    15961 ataatagctg ttcctgataa aactggcccc caagttccaa agagcaagtg acctagaaag
    16021 gctccgatcc aaccgagaaa catttttcca aaacatccca ttcgctctcc acgattggtc
    16081 atagcacctg ctaaaaatcc cactaggaga ccaacgaaca tacttcctaa catattatct
    16141 ccttaatttg cccaattccc attacggaaa agaggtactc gcgttccatc ctcacgaata
    16201 ccatcgatat ccatttggtt agaaccaatc ataaagtcta cgtgaacatc tgaacggtta
    16261 agccctgcag cttcaagctc ctcttcgctc atctccgctc catcaacaac gctagtcgca
    16321 taggctgcac cgatagccaa gtggtttgac gcattttcat cgaaaagggt gttaaagaag
    16381 gtaatgcctg actgagaaat tggacttgga tctggtacca aggcacattc acccaaggca
    16441 cgcgcacccg cattttcaaa gacaaggtct ttcataacct gatcaccctt ctcagcagtg
    16501 atatctacga tttgtccatc cttaaaggtc accttaatgc cttcaatgat atttccgttg
    16561 tagctaagcg gttttgtaga agtgacataa ccatctgcac gacggaagtc aggcgctgtg
    16621 aagacctctt ctgtcggcat atttggcaag aattcttcgc cctgtgcatt gacagcacca
    16681 gctgattccc aaacgtggtt ctttggcaaa ccaagtgtta aatctgttcc tggcgctgtg
    16741 tagtgaaggg ctgaaaattg ctccttatta agcatattgg ccttgctctt gagaatggct
    16801 gcatgttcct cccaagcctt aacaggatct gcttcgtaga cacggcaagt tttgaaaatt
    16861 tggtcccaaa ggaaatcaac tgcttcttcg tcgctcgcag catttgggaa gactttctta
    16921 gcccactcaa gtcctgctgc agctgctaca gtccagctaa ccttgttaga ttgagttgcg
    16981 atacgcatag gcttcatggc aagtcccata gctttagcag aagctgaaag cttgtcagcg
    17041 tccactccgt tcaaggcacc cggatcagat gaacgaactc caagacggct agccttgttc
    17101 tccaagagat agttcatctc agcaatcttg tattctggca cattgtccaa acgctccatc
    17161 ggggcatgga ggaatttctc acggttaatc acatcatctg tccactgaac gatgacctca
    17221 tgcgcaccca aggcataagc ttctttcacg attagatgtg ccaattcacg ttgctccaca
    17281 tcaatagaga gagccaaagt gtgaccaggt tgcacgttaa ttccgttcgc aaccaacaat
    17341 ttcgcatatt tttctagatt ttctttaaaa tttggtaaaa ccattctgtt ttctcttttc
    17401 tatttttatt tttctctcaa agcagaaaag attcctgcta aagcaatagc acctgacaag
    17461 agtgctgtcg atagaagaat tgtacgatca gcaagttcta attgatattc aaataccttc
    17521 ttagccggct tatcttccgc aaatattctt agtttcatga gaaccccctt aaaatagatt
    17581 aaaataaatc actgtgactg cctgtcctca gcaaatttaa aatcaattcc gacttgtcta
    17641 ctttataaac caaaagccaa tctggctggg tatggcattc acgaactcct tgaaaatgct
    17701 tggatgccgt caatgaatga tcacgatatc tggcaggatg ttctttttct tgaaccagaa
    17761 aattcaaaac ttcttctaat aattctgcct tcaaaccacg cttcatagcc aacttaaaat
    17821 cttttttaaa ctgtttatga taacgaatct taagcacgta agtcctccat caaatctgag
    17881 actgattcaa aagactggct catattacga ttttggtcta aatccgttaa cgcttggagc
    17941 aacttccgat tttcgtctag tctaacatca aaaggtagtc cctgatattg aattgcctga
    18001 cgaaggaaaa tattaatagc tgttgtcata tccattccca gattactaaa cacctgttgg
    18061 gcctgctcct taacctcact atccagacgg atgcttatac tcatctttga catactctca
    18121 ccctctttcc atagactatt ttaacaaaaa agaaagctaa tgtaaatcta ttggatatac
    18181 gttagcctct tttaatagat tattaagcaa ttttttaaaa caactcatca aacaaactca
    18241 actggttatc ctctggcata tttccaagaa tacccatctc atccatcttt tcaaccaagg
    18301 ttgatgagag tccaccacgc ttgcgtagtt ctgttttaga gaggaattct ccctcttcac
    18361 gcgcccgcac cagttgcttg gcaacgttct ctcccagacc atccattgct acaaatggtg
    18421 ggataagggt atccccgtcg atgaggaact ctgtcgcctg actacagtag agatctaatt
    18481 taccaaactt gaaacctcgt tcccacatct cattgacaat ctcaagagtt gtatagagat
    18541 cgatttccac attagaggct tcattgttct tccgtttttc agagatttct tccattctgc
    18601 gcttgatggc ctccaagccc gcacccatgg tcttgatatc aaaagcctta gcacgaatgg
    18661 agaagtaagc acagtagtaa taaataggat ggtgaacctt gaagtaagct acacgcaagg
    18721 ccatcataac gtaggctgcc gcatgggcct tagggaacat gtacttaatt ttcccacagg
    18781 attcgatata ccactctggc accttattag ccttcatggc ttcgatatag ccatttctct
    18841 cctcttctga aatctttagc cacaaaccct tacgtacccg ttccataatg gtaaaggcca
    18901 tcttaggttc cagacccgca tgcatgaggt aaaccatgat gtcgtcccga caaccgataa
    18961 cagtcgatag gtccgctatt ccttgcttaa tcagatcctg agcattcccc aaccaaacgt
    19021 cagtaccgtg ggacagacca gacagctgaa gcaattccgc aaaggttgtc ggatgggttt
    19081 cgtctaccat tccacgtacg aaatttgttc caaactctgg aatccccaac atacccgtag
    19141 gcgttccaat ttgttcaggt gttaccccta gcacatcagt cccagaaaag agtgccatca
    19201 cgccttcgtc atccatagga attttattag ggtcaatacc agacaaatcc tgaagttttc
    19261 gaatcatggt cggatcatca tgtcccagta catcgagttt gaggacgttc tcatcgatat
    19321 cgtggaagtt aaagtgagtg gtctgccatt cagccgtgac atcatctgct ggatactgga
    19381 caggcgtaaa atcgtagaca tccatgtagt tcggaataac aacgattccc cccgggtgtt
    19441 ggcctgttgt ccgcttgaca cccgccgctc cttgagcgag gcgttctact tctgcatcac
    19501 gataaaactt gccataatct cgctcgtaac ccttgacaaa tccataggca gtcttggcag
    19561 ctaccgtacc aaccgttccc gcacggaagg catattcttc accaaagata tcacgcacat
    19621 ccaagtgggc gctaggctga tcttctcccg agaagttcaa gtcaatatca ggaaccttat
    19681 ccccatcaaa accaaggaag gtctcaaacg gaatatcctg tccgttttta ctgagtttgt
    19741 gaccacagtt tggacagtcc ttatggggca tatcaaatcc tgaaccgtac gaaccatctg
    19801 tgataaactc actgtactga cactgaccac agacatagtg aggagagaga ggattgacct
    19861 ccgtaatccc aatcatggtc gcaacgaaac tagatccgac agatccacga gaaccaacca
    19921 agtaaccccg ttcattagaa cgttgcacca gcatctgcga tgccagataa atcacagcaa
    19981 atccattccc cagtatggat gttaattctt tttcaatccg caaatcaaca atatctggca
    20041 gcggatttcc ataaatctca aaagctttct tataggtcaa ctcagcaact gtttcttcag
    20101 ccttgtcgat gaaaggcgta tacaagtcac ccttaacgac ttcaacgggt tcaaatattt
    20161 ctgccaaggc attggtgttt tcaataacca gtttacgagc cagttcctct cccaaaaagg
    20221 caaattcatc caacatctca ttagtcgttc gaaaatgagc ctttggaagt ggcgctggtt
    20281 gggcatgttc accatgaccg atagttcggt taatcatcgc accctgtccc aaactacgga
    20341 cgataatttc acgataaatc tcttcttccg gttcgatata gtgaacattt cccgtagcca
    20401 gaacaggctt gccaaggcga tctccaacct ctatcaaact cttgataatg gtctggagtt
    20461 cctccatatc cttgacctgc tctttggcaa tcaagggcgc atagatagcc ggtggcatga
    20521 cctcgataaa gtcataatac ttggccacct caaccgccgc atccacacct tgagaaacga
    20581 ccacgtcaaa aacttcaccc tctgaacagg ctgaacctaa aatcaagccc tctcgatggg
    20641 catctagaac cgttctcgga atccgtggca ctccttcaaa atacttggta ttagacaagg
    20701 aaaccagctt aaagatattt tttagaccta cctgattctt gacatagatg gtcgcatgct
    20761 tgatccgagc ttttttgtaa gaatctggac tgattagatc aatgttgagt ctagctaaat
    20821 cggtcacacc atgtttttct gctacctctt tgataaagat gaaaagcaga cgaccagtcg
    20881 cttccgcatc gtagttggcc atgtggtgat gttccaaggc cacaccaaaa cgcttggtca
    20941 aaggccccaa accatggcgt ttatactcag gatagaggtt tctagcaaac tccagcgtat
    21001 caataactgg ctgactaatc tttggaagac catgacgctc ataattagca ttcataaagc
    21061 caacgtcaaa ggcagcattg tgggcaacta ggaccgtatc cttgcaaaat tcttggaatt
    21121 cttgcaaaac ttgttctagt ggtttggcat ttttgacatg atcatctgta attccagtta
    21181 actctgtagt aaaagctgac aagggatgcc caggattgat aaattcatca aattcagcaa
    21241 taacattccc cttgtacatc ttagaggccg caacctgaat caagtcatta tagatagctg
    21301 aaagtcccgt cgtttccacg tcaaagacca cgtaggttgc ttctgataag tccatctcca
    21361 cttcgttata gacgataggg acacggtcct ccacgatatt ggcttccatc ccatagatca
    21421 gctggattcc cgctttctta gccgccttat agccatgtgg aaaggactgg acattcccat
    21481 ggtctgtgat agcaaccgcc ttgtgtcccc acttagcagc tgttgcaaca atctcttcga
    21541 cctctggcaa agcatccata gtcgacatgt tagtatgagc atgaaactca acccgacgct
    21601 caccttctgg catcaaatcc ttccgctcat agtgaacaac ttcctgcaga tcctgtacgt
    21661 tcatagtcaa atcgcgtgtg aagttattca tctccacatt ccctcgaact cggagccaag
    21721 aattcttctt gatgaggtca aacttctggg cctcttcctc gtttttaacc cacttttgca
    21781 tagaaaaact tgaagtatag tccgtcattt taaagttgat taaaacacga cctgttctag
    21841 tcactttttg ctccacatca aaaacaaccc cttcaaatac cagacgattt tcctctgtcg
    21901 tcacttcgat cataggagta atctccgcct tatccagctt gggtttagct gcagcttttt
    21961 tcgcttgaaa atcaaagact ggtttctctt ccacttgagg aggtgccatc tgctccagtt
    22021 gttccatagc acggagcgct tcctcattgg cagcttgaac aatctgctca ttttcagcat
    22081 gaaaggcctc ttcctgctct tgggtcagga catcattctt ctcaacttga cagttaaaag
    22141 tttgaaaacc aaacttttca agttgcttgg ctaaattagg aagatgattc ttcttaaaat
    22201 gttccttatc aatcgcttca gatccttcaa taaatagctg attaccctca gcacgaactt
    22261 gcaaattttg ataaagggac ttaaaacctt gactagcaca tggaccttca gagaaagcct
    22321 ccctatagta ggactgcaag agctgatttg aaaattcttg agaccgagcc ttaatttcaa
    22381 aaacagcttt attgcctgtc ttagaaaatt cttcgctcaa acctttcttt aattctaaaa
    22441 agatttcaat cggtaaaata ttagaaaata cgaaatgaaa ctcccatacc ttactaattt
    22501 tatgaaccac aactcgctca atattggcct gtgctaaagc aggagcctgt ctcatttcag
    22561 caggcatccc caattgattc atcaaaattt caaaactatt tgacattcat tttcctcaca
    22621 ttattcttct actattttac catatttaga ggtattttct aaagacaaaa ggaagccact
    22681 aagtgacttc cttctagagt gaggacggat tagtcttcac ctttattttt cttaataatt
    22741 tcttcttgta ctgacttagg tacatcttcg tagtggtcaa ataccatcat gaatgtacca
    22801 cgtccttgag atgcagaacg aagaactgtt gcgtaaccga acatttcagc aagtggaacg
    22861 taagcacgaa cgatttggct gttaccgtgt gcttccatac catctacacg tccacgacga
    22921 gcagttacgt gacccataac atcaccaagg ttttcttctg gaacagtgat tgttacaagc
    22981 atcattggtt caaggatagc tggttgtgct gatttagcag cttctttaag ggaaagtgaa
    23041 gccgcaatct tgaaggcagt ttcagatgag tcgacatcgt gatatgaacc atcataaagc
    23101 ttagctttaa cgtcaaccat tgggtaacct gcaagaacac cgttagccat agattctacc
    23161 aaaccttttt caaccgctgg gataaattca cgaggaacca caccaccgac gattgcgttt
    23221 tcgaattcga atcctttacc ttcttcgttt ggagtaaatt caatccacac atcaccgaat
    23281 tgacctttac caccagactg acgtttgaag aatccacgtg cttgagtaga agcgcggaat
    23341 gtttcacggt aagatacttg aggagcacct acgttcgctt caactttgaa ctcacgacgc
    23401 atacgatcaa caaggacgtc aaggtgaagt tcacccatac ctgagataac tgtttcacca
    23461 gtttcaacgt ttgtttcaac gcggaatgtt ggatcttctt cagccaattt ttgaagggcg
    23521 atacccatct tgtcttggtc agctttagat tttggctcaa ccatcaattg gataactggt
    23581 tctggaacgt tgattgactc aaggatgatt ttagattttt catctgtcaa tgagtcacca
    23641 gttgtagtat ctttcaaacc aacggcagca gcgatatcac ctgagtaaac agtgtcgatt
    23701 tcttgacggc tgttagcgtg catttgaagg atacgtccga tacgttcacg tttaccttta
    23761 gaagtattca atacgtatga acctgattga agaacacctg agtaaacacg gaagaatgtc
    23821 aaacgaccta cgaatgggtc agtcatgatc ttgaaggcaa gagctgcaaa tggctcttcg
    23881 tcagatgctg gacgagtttc ttcagcgtct gtatctgggt taataccttt gattgctggg
    23941 atgtcaagtg gacttggaag gtagtcgata accgcatcaa gcatcaattg aacacctttg
    24001 tttttgaagg ctgaaccaca caatactggg aagaattcaa cgttgatagt cgctttacgg
    24061 ataccagctt tcaattcttc gttagtgatt tcttcacctt cgaggtattt catcatcaat
    24121 tcttcgtcag tttcagcaac tgcttcaatc aatttttcac ggtattcttg agcttggtca
    24181 aggtattcag ctgggatgtc ttcttcaagg atatccgtac caaggtcgtt agtatagatt
    24241 tcagctttca tcttgatcaa gtcaatgata ccacggaagt catcttcaga accgattggc
    24301 aattggattg ggtgtgcatt tgcttgaaga cgatcgtgaa gtgtgcttac agagtaaagg
    24361 aagtcagcac cgattttgtc cattttgttg gcaaatacga tacgtggaac tccgtactca
    24421 gttgcttgac gccaaactgt ttcagtttga ggttcaacac ctgattgtga gtcaagaacg
    24481 gtaaccgcac catccaatac acgaagagaa cgttgtactt cgattgtgaa gtccacgtgt
    24541 cctggtgtgt cgatgatgtt tacgcggtgg ttgttccatt gagctgttgt cgcagcagat
    24601 gtgatcgtga taccacgttc ttgctcttgc tccatccagt ccatttgtga cgcaccttcg
    24661 tgagtttcac cgattttgtg gattttacca gtgtagtaaa gaatacgctc agtagttgtt
    24721 gttttaccgg catcgacgtg agccatgata ccgatattac gagttttttc aagtgaaaat
    24781 tcgcgtgcca tgaggtttgt ttctcctatt tatttttgat ttctattcta ttataacacg
    24841 attttaataa aaacggatag gcaggaccta cccgttctca atgttttcat gctattgttg
    24901 gtttcaactt acgagatggt aagctgagtt atagctaata ctaatcgatt tagctaattt
    24961 gaacccgggc taaagttagt tagccgatgt gagctggaac gggatgctgc gtgaaaaaga
    25021 taaaactcct tgtattcgtt gaatactgcg tcagtttcct attttcacct tgcatcctta
    25081 ccgtgcctag catcatgatt tagttgagct caagctaaaa gtctggagaa aaagatgaat
    25141 ctcattggtt gcaaccgcaa cctgcttcga ttccctattt tctctgggac tttcttaacg
    25201 ctttcgcatc ctatcttacc aacggaagtg tgcgaatgca cggttagctt cagccatacg
    25261 gtgagtatct tcacgtttct taacagctgc accagtgttg ttagcagcat ccaagatttc
    25321 ttttgcaaga cggtcttgca ttgtgtgttc accacgaaga cgagcgattg ttaccaacca
    25381 acgaagtcca agtgttgtac gacgttctgg acgaacttca actgggactt ggtagttaga
    25441 accaccaaca cgacgtgcac gtacttcaag tacaggcatg atgttttcca tagctgtttc
    25501 aaatacttca agtgcatcgt tgccagtagc ttctttgatt tgctcaaaag caccgtaaac
    25561 gattgaagca gcagtaccac gtttaccatc aagcataacg cggttgataa gacgagtaac
    25621 tagttgtgaa ttgtatagcg gatctggcaa tacgtcacgt tttggagctc tatttttacg
    25681 actcatttct ctttatcccc tttccttatg cttttggacg tttagtaccg tatttagaac
    25741 ggccttgttt acgatcgtta acacctgcag tatcaagtgc accacggacg atatggtaac
    25801 gtacccctgg aaggtctttt acacgtccac cgcgaagaag caccacgctg tgctcttgca
    25861 agttgtgtcc gatacctggg atgtaggcag taacttcgat aaggttgctc aaacgtacac
    25921 gagcgaattt acgaagggct gagttaggtt ttttaggtgt cattgttcca acacgagttg
    25981 caacaccacg tttttgtggt gaagaaacgt ttgtttgaac ttttttatga ctattgtaac
    26041 caacgttcaa agctggtgat ttagattttt ctacttttga tttacgcggt ttgcgaacca
    26101 attggttaat tgtaggcatc tacattctcc tgtgtttttt tatttttggt gatgatacac
    26161 ttggtgacag atatcatctg tgtgtacttt tgcaacattt gtcagcacgt ccctgtacac
    26221 tcttgagaga ccaaaagtaa aaagtaccgt ctattattgt aacaaaattt tcccttgctt
    26281 gtcaagatat ttttcttttt tattggtaat gttagagatc aatttctgaa taaaaatagc
    26341 tgggaacaca tcatcttcct aataatacgg cttggcttat gtgacatttt tatctccgtc
    26401 atttatactg atatataaaa tagtacagaa aacttctcaa aagtaagaat ttttttcaca
    26461 aatcaaagaa aacgcttgca tattgtttta ctacatgcta tactgatata gaaatttatt
    26521 gattggagaa tcattatgag aaaaacacca tctcacactg agaaaaaaat ggtctacagc
    26581 atccgttccc tcaaaaatgg aactggttct atccttatcg gcgcaagcct tgtcttgctt
    26641 gccatggcta caccaactat ctcatccgac gaaagtacac caaccactaa cgaacccaac
    26701 aacagaaata caaccaccct tgcccaacct cttactgata cagcagctgg ctctggtaag
    26761 aacgaaagtg atatttcttc acctagaaat gcaaacgctt ccctagagaa aacagaagaa
    26821 aaacctgcaa cagagccaac tacttctact agtccagtaa caactgaaac taaggcagaa
    26881 gagcccatcg aagataacta cttccgtatc catgtcaaaa aacttcctga agaaaacaag
    26941 gatgctcaag gactatggac ttgggacgat gttgaaaaac catctgaaaa ctggccaaac
    27001 ggagctttgt ccttcaagga tgccaagaaa gatgactacg gctattacct agatgtcaaa
    27061 ttaaagggag aacaagccaa gaaaattagc ttcctcatca acaatacagc tggaaaaaat
    27121 ctaaccggcg ataaatctgt agaaaaacta gttccaaaaa tgaacgaggc ttggttagac
    27181 caagattaca aggttttctc ttacgagcca cagcctgcag gaactgttcg cgtcaactac
    27241 taccgcacag atggcaacta tgacaagaaa tctctctggt actggggaga tgtaaaaaat
    27301 ccaagtagcg ctcaatggcc tgacggaaca gactttacgg ctacaggcaa atatggccgc
    27361 tatatcgaca ttcctcttaa tgaagccgca agagaatttg gatttttatt actagatgag
    27421 agcaaacaag gagacgacgt gaaaatccgt aaagaaaatt ataagttcac agatttgaaa
    27481 aatcatagcc aaattttcct aaaagacgat gatgaatcga tttacacaaa tccatactat
    27541 gtccatgata tccgtatgac aggagcccaa cacgtaggca cttctagcat tgaaagtagc
    27601 ttttcaacac ttgtcggtgc taaaaaagaa gatatcctca aacactccaa catcactaat
    27661 cacctaggaa acaaggtaac tattaccgat gttgcaatcg atgaagctgg taagaaagtg
    27721 acctacagcg gagatttctc tgacacaaaa catccttata ctgttagcta caattccgac
    27781 caattcacta ccaaaacaag ctggcacctg aaagatgaga catacagcta tgatggcaaa
    27841 ctgggagctg acctaaaaga agaaggaaaa caagttgatt tgaccctttg gtcaccaagt
    27901 gctgataagg tttctgttgt tgtctacgac aagaatgacc ctgacaaagt agttggaact
    27961 gtcgctctcg aaaaagggga aagaggaact tggaaacaaa ctctagacag cacaaacaaa
    28021 ctcggaatca cagatttcac tggctactat tatcaatacc aaatcgagcg tcaaggtaaa
    28081 actgttcttg cactcgatcc ttacgctaaa tctcttgctg cttggaatag cgacgatgcc
    28141 aaaattgacg atgcccataa agtggctaaa gccgcctttg tagatccagc taaactcgga
    28201 cctcaagact tgacttatgg taagattcat aatttcaaga ctcgtgaaga cgccgttatc
    28261 tacgaagctc atgtgcgtga cttcacttca gatcctgcca ttgcaaaaga cttgaccaaa
    28321 ccatttggga cttttgaagc cttcattgaa aaactagact atctcaaaga cttgggtgta
    28381 acccatatcc agctccttcc agtcttgtct tactactttg tcaatgaatt gaaaaaccat
    28441 gaacgcttgt ctgactacgc ttcaagcaac agcaactaca actggggata tgaccctcaa
    28501 aactacttct ccttgactgg tatgtactca agcgatccta agaatccaga aaaacgaatc
    28561 gcagaattta aaaacctcat caacgaaatc cacaaacgtg gtatgggagc tatcctagat
    28621 gtcgtttata accacacagc caaagtcgat atctttgaag acctagagcc aaactactac
    28681 cactttatgg atgccgatgg cacacctcga actagctttg gtggtggacg cttgggaaca
    28741 acccaccata tgaccaaacg gctcctagtt gactctatca aatacctagt tgatacctac
    28801 aaagtggatg gattccgttt cgatatgatg ggagaccatg acgccgcttc tatcgaagaa
    28861 gcttacaagg ctgcacgcgc cctcaatcca aacctcatca tgcttggtga aggttggaga
    28921 acctatgccg gtgatgaaaa catgcctact aaagctgctg accaagattg gatgaaacat
    28981 accgatactg tcgctgtctt ttcagatgac atccgtaaca acctcaaatc tggttatcca
    29041 aacgaaggtc aacctgcctt tatcacaggt ggcaagcgtg atgtcaacac catctttaaa
    29101 aatctcattg ctcaaccaac taactttgaa gctgacagcc ctggagatgt catccaatac
    29161 atagcagccc atgataactt gaccctcttt gacatcattg cccagtctat caaaaaagac
    29221 ccaagcaagg ctgagaacta tgctgaaatc caccgtcgtt tacgacttgg aaatctcatg
    29281 gtcttgacag ctcaaggaac tccatttatc cactccggtc aggaatatgg acgtactaaa
    29341 caattccgtg acccagccta caagactcca gtagcagagg ataaggttcc aaacaaatct
    29401 cacttgttgc gtgataagga cggcaaccca tttgactatc cttacttcat ccatgattct
    29461 tacgattcta gcgacgcagt caacaagttt gactggacta aggctacaga tggtaaagct
    29521 tatcctgaaa atgtcaagag ccgtgactat atgaaaggtt tgattgccct tcgtcaatct
    29581 acagatgcct tccgacttaa gagtcttcaa gatatcaaag accgtgtcca cctcatcact
    29641 gtcccaggcc aaaatgatgt ggaaaaagag gatgtagtga ttggctacca aatcactgct
    29701 ccaaacggcg atatctacgc agtctttgtc aatgcggatg aaaaagctcg cgaatttaat
    29761 ttgggaactg cctttgcaca tctaagaaat gcggaagttt tggcagatga aaaccaagca
    29821 ggatcagtcg gaattgccaa cccgaaagga cttgaatgga ctgaaaaagg cttgaaattg
    29881 aatgccctta cagctactgt tcttcgagtc tctcaaaatg gaactagcca tgagtcaact
    29941 gcagaagaga aaccagactc aaccccttcc aagcctgaac atcaaaatga agcttctcac
    30001 cctgcacatc aagacccagc tccagaagct agacctgatt ctactaaacc agatgccaaa
    30061 gtagctgatg cggaaaataa acctagccaa gctacagctg attcacaagc tgaacaacca
    30121 gcacaagaag cacaagcatc atctgtaaaa gaagcggttc gaaacgaatc ggtagaaaac
    30181 tctagcaagg aaaatatacc tgcaacccca gataaacaag ctgaacttcc aaatacagga
    30241 atcaaaaacg aaaacaaact cctatttgca ggaatcagcc tccttgcgct ccttggtctc
    30301 ggtttcttac taaaaaataa aaaagagaac taaactagcc ctcctataga aaaatccccc
    30361 aagcattata gctcggggga ttaatttttg tacaatattt gttgtcctaa taaacttgat
    30421 taggattttt tattaagcct ctttcatagc aaaataagct cgtactttgg gtgcaacttg
    30481 tgttccgaat agttcaatag ctctcagaac ctggtcatga ggcatagaac caagcggtag
    30541 atgaagcatg aagcggtcca atcctaaatc ctctatcatg cgaatcaatt tttcggccac
    30601 ctgatctgga ttgccaacaa acatggcgcc atttggccct acctgctcca aatattgctc
    30661 ataacgcaat tcctgccagt gcggacggtc tttggaaata gcatccacca cttgcttagt
    30721 cggatggaaa taatctttca ccgcctgctc accatcttcc gcaatccacc cccaagaatg
    30781 ggctcccact ttcaagtctt tgtcagcatg gcccgcttcg cttccaatct cacgataagc
    30841 ctgaatcaac tttttaaaat aacgtggatt accaccaata atagcatata caatcggtag
    30901 accagcctga gcaatcttca ctgttgattc gacatgacca cctgtagcta tccacaaggg
    30961 caatttgtcc tgaactggac gaggataaac ttctttacca gcaatcgttt gagtcaatcg
    31021 accttgccag tctaacttgg tcttttcatt gactaactga agcaagtcta atttctcatc
    31081 aaaaagagag tcgtagtctt tcaagtcata accaaacaga gggaaagatt ccgtgaaaga
    31141 gccccttcca gccataatct ccgatcgtcc atttgacaaa gcatcgatag tggcatactg
    31201 ttggaacaaa cgaatcgggt ccatgcttga cagaatgctg actgcactgg tcaaacggat
    31261 tttcttggta ttgactgccc cagcggccag gacaatctct ggggctgata ctgcaaaatc
    31321 cgcccgatgg tgctcgccaa ttccatatac gtccaaacca accttgtcag ccagctcaat
    31381 ctctgccacc aactggcgaa tgcgttcagc atgactgtaa gtttgtccag tcccttcaag
    31441 ctccgttatt tccccaaatg ttgaaattcc caattctacc attgtgattc tccttgtcta
    31501 tctctgtcct tcaatttgaa aaattattct aatactcaat gaaaatcaaa gagcaaacta
    31561 ggaagctagc tgcaggctgc tcaaaacagt gttttgaggt tgtggataga actgacgaag
    31621 tcagtaacca tacctacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    31681 ataacacgaa tcttgagtac aagcaaccaa tttgctcaca agaaaaagcc tagataacta
    31741 gactttttta gcttattcta ccgttactga cttggcaagg ttacgtggtt tgtccacatc
    31801 gaggccacga tggagggttg caaagtaagc gactaattgc gttggtacga ccattgaaat
    31861 tggtgagagg tatggatgta cggtcgtaag gacgatatcg tcggtatctt tggctacatt
    31921 ctcttctgcg atagtgagga ctttggcacc acgggctgcg acctcttgga tatttccacg
    31981 agtatggttg gcaagaactg gatctgacaa gagagccaaa acaggcgttc cttcttcaat
    32041 caaggcaatg gttccgtgct tgagttctcc tgcagcaaag ccttcacact ggatataaga
    32101 aatctctttg agtttgagac ttgcttccat ggctacgtag taatcttgac cacgtccgat
    32161 gtaaaaggcg ttacgagttg tttcaagaag ttcacgaacc ttgacttcaa tggtttcttt
    32221 ctctgaaaga gttgattcga tagactgagc tacgattgac aattcatgaa ccagatcaaa
    32281 gacttgcgct ttagcattac catttgcttc tccgactgct tttgcaagga aggcaagggc
    32341 tgcgatttgc gctgtatagg ctttagttga tgccacggca atttcaggac ctgcgtgaag
    32401 gagcatggta tagttggctt cacgtgagag ggttgaacct ggaacgtttg tcactgttaa
    32461 gcttggaatt cccatttcat tagccttgac caaaacttga cgactatccg ctgtttcacc
    32521 agattggctg ataaagatga agagtggttt cttgctgaga agtggcatac cgtagcccca
    32581 ctcagatgag attccaagtt caactggtgt atctgtcaat tcttccaaca ttttcttaga
    32641 agcaaatcct gcatggtaag atgttccagc tgcaaggatg tagatgcggt ctgcgtcttg
    32701 aacagcctta atgatatctg ggtctacgac aacttgacca gcctcatctg tgtaggcttg
    32761 gatgagtttc cgcataacag ttggttgctc gtcaatttcc ttgagcatgt agtaagggta
    32821 agttccctta ccgatatctg acaagtcaag ttcagcagtg tagctagcac gctcacgacg
    32881 atttccatca tagtcttgaa cttccacact atcagccttg acgattacca actcttggtc
    32941 atggatttcc atgtattggt tagtttcacg aatcatagcc atggcgtctg agcagaccat
    33001 gttatagcct tctccaagac caatcaaaag tggtgattta tttttagcta cgtagatgac
    33061 ttcaggatct tgtgagtcaa ccaaggcaaa ggcataagaa ccacggatga tgtgaagggc
    33121 ttttttgaag gcttcaagaa ctgagagccc ttcttcttcc gcaaattttc caatcaaatg
    33181 aacggctatt tcagtatctg tctgcccctt gaagtggtga cctgcaaggt attcttcctt
    33241 gatttcaaga tagttctcaa tcaccccatt atgcaccaag acaaaacgtt ctgtcttaga
    33301 gcggtgtggg tgagcattgt cctcagttgg ttttccgtga gtagcccaac gagtatgtcc
    33361 gataccagtt gttccctcaa caccagctgt cttggcagac aattctgcaa tacgaccaac
    33421 ctccttcacc aaatggttat cagcaccatc taggacaaaa attcccgcag aatcatagcc
    33481 acggtattca agcttttcaa gcccttgaat caaaatatca gttgcatttg tgtttccaac
    33541 aacaccaaca attccacaca tagtattttc ctttttaaaa ttggtatagt ctaattaacc
    33601 aaattggcaa tcagtgaagt tattataaaa cttgtttttt aaattgtcaa gaaaaaattg
    33661 gtatagttca aattaagctc ctgtaagcat aaaaactctg accgattggg ataatcagtc
    33721 agagtccttt ttaaaatcca ttattatcgc ttaattcttt gaaccagtgg cctgatttct
    33781 tcagacgacg ttcttgcgtt tccaagtcta attcgaccaa accataacga tttttatagc
    33841 tgttgagcca tgaccagcag tcaataaagg tccaaatcaa gtagccctta cagttggcac
    33901 catcttcaat ggcacggtga agttcacgaa gatgaccttt tacaaagtca atacggtaat
    33961 catcttgaat cattccatct tgacggaatt tttcttcccc ttcaacaccc ataccattct
    34021 cagtcaacat ccactcaata ttgccataat tttccttgat attttgggcg atgtcataaa
    34081 tcccttgctc ataaatctcc caaccacggt gagaattgat tttacgtcca ggcatcacat
    34141 aaggctcgta aaaatgttct ggtaagagtg gactctctgg atgcttagca aatcgaggag
    34201 ccataacacg caaaggttga tagtagttca caccaaggaa gtccaccgta ttatcacgaa
    34261 tgagttccaa ctcttcctct gtagcatcag gtaaaagacc gtgttcatgc aagatttcta
    34321 ccaactcctg tggataagtc cccaagacag atggatctaa gaaagattgg gcctgaaaaa
    34381 gggccgcaat acgagctgcc ttgacatcag caggatgctg gctacgtgga taagccggtg
    34441 tcaagttgag gacaatccca atcttggaat caggcaaaag ttcatggcaa gccttaacag
    34501 cccggctgct ggccaattgt gtatgatagg ctaccttaac agctgcctct gcatccacct
    34561 tatgtggata atgggcatca taaaaataac caaattctac aggaacgatg ggctcgttaa
    34621 aggtaatcca ttgatccact aaatctccat aagtctcaaa acaaaaacga gcatagtctt
    34681 cataggctga gactgtcgcc ttattttccc aaccatcacc atcctcttga agggcaaaag
    34741 gtaaatcaaa atgatagaga ttgactaaca gacgaattcc tttagcctta atagcctcaa
    34801 agaccttacg ataaaaatcc acaccttgag ggttgacttt tccacagcct tgtggaaaaa
    34861 tccgtgacca ctgaatagaa gtccgaaaga ctgtgtgacc agtctctaac aaaagctcaa
    34921 tatcccgctc ccaattttca taaaaagtcg atgtcttatc tgaaccaatc ccattatagt
    34981 aacgatttgg ctccacttgg aaccagtaat cccagagatt gtctccctta ccgtcaccag
    35041 ctacacgtcc ttctgtctgc ggtccagaag tagaggatcc ccagacaaaa tcctttggaa
    35101 atcttagcat aacatttacc tctttatcta ctcatttctc ccattataca gaaaaaacaa
    35161 ggtaaaaact agttacattt tttccttgtt tttcttctga ttatagtttt tatttcttgc
    35221 ttaggatttc aagcgtttca agcacgttat ctgcatgaac ctcaatggtg tcaccagttg
    35281 ccttgatctt aacttctaca atgccatcgg ccgctttttt accaacagtg atacggattg
    35341 gaagaccaat caagtcacta tcgctaaatt taacaccgac acgttcgtta cggtcatctg
    35401 tcaagacttc ataaccagct cccatcaagc ttgcttcaag tttttctgtc aaggcttgcg
    35461 cttcttcatc cttgacattg acagtaatca aatgcacatc aaatggtgcc aattctttag
    35521 ggaaattgat tccccaagcg taacggtatt caccttttgg cgttttgtta acaaagaggc
    35581 gagcgtgttg ctccatcact gctgaaagaa gacggctgac accgataccg taacatccca
    35641 tgatgattgg cacagcacga ccattttcat ccaagacatc tgctcccatg cttgctgagt
    35701 agcgagttcc gagtttgaaa atatgaccga tctcaatacc acgcgcaaag ttaaggacac
    35761 cttgtccatc tggggaaatt tcaccctcac gaacttcacg gatatccaca tattctgcag
    35821 taaaatcacg gcctgggttc acaccagtca agtggtagcc atcttcgtta gcaccgacaa
    35881 ctgcattgcg aacatcttgc accttacgat ctgcaataat tttaatattc tctggcaaac
    35941 caactggtcc aagtgaacca aatcctgctt gaacaacatt cgccacttct tcttcgctag
    36001 caacgtcaaa gaaatctgct cccaagtgat ttttcaactt gacttcgttg agttggtcat
    36061 ttccaactag aagggctgca acaagctcac catctgcaat gtagaagagg gttttaatcg
    36121 tttgttcttc tggaacattg aggaaggctg caacttcatc aattgattta acatctggcg
    36181 ttgcaacacg agtaacttct tcttcagcga caacacggtt gcttggtttg tactcgtttg
    36241 ttgccatttc taagttagct gcatagctag actcacttga gtaagcaatg gtatcttcac
    36301 cagagactat ccatttgagc aattctgcct tgatttcttc ttgcacttct gcaggaattt
    36361 cgtcaaatga ggcaactgac ttgtccaaga caacccagcg gtcaaggtct gtacgagcag
    36421 atgtaatggc cataaattct tggctatcct taccacccat ggctccaccg tcaccaataa
    36481 tagccttgaa gtctaaacca ctacgagtga aaatacgctc ataggctgct ttgtactcat
    36541 cataaacact atccaaacta tcatagttag cgtggaaact ataagcatct ttcatgataa
    36601 actcacgtgt acgaagaagt ccattacgcg ggcgtttttc atcacgatac ttgggctgaa
    36661 tttgataaag gttgagtggc aattgcttgt aagatttaac agaatcacgg acaatagctg
    36721 taaaggtttc ttcgtgagtt ggacctaaga taaagtctga tttttcacgg ttttttagtt
    36781 tgtaaaggtc ttcaccatag gtttcgtaac gacctgattc acgccacaat tctgcactaa
    36841 gaagggcagg agccaacatc tcaacagcac caatcttttc gaattcttgg cgcatgatgt
    36901 ttttagcttt ttcaatcaca cggttggcaa gtggtagata agaataaaca cctgctgaaa
    36961 cttggcgaac ataaccagca cgcaacataa gagcatggct gataacttga gcatcgcttg
    37021 gcatttcgcg aagcgttggg ataggcattt tactttgttt cataatattc ctcgattatc
    37081 taaaaaagag tcgcataatg tcattccaag tcacagcaat catcaagaca accatgatga
    37141 ccactccggc caaggtgaca taggtttcaa tttcttgttt caatggtttg cgacggatgg
    37201 cttctaggat attgagcaca atcttaccac catccaaggc tggaatcgga ataagattaa
    37261 aaatcccaat attgatggaa atcattgcca agaagtacaa gatattctca attccatttt
    37321 tagcagcatc actacttgcc ttaaagatag caacaggtcc acccaacttg ttcaaatccg
    37381 gttggaaaat cagatttttc agagctgaga gaattcggag agctgagtca gcagcagttg
    37441 taaaaccacc tacaaacatg gatagaaaat ctgacttaac ccccggttga acacctagaa
    37501 ggtaacgacc ttgactatct tcgggtgtaa cagtgacttg tttgtcactc cccttttcag
    37561 aaatagtcac atccaaagtc ggtgccgtct tatctttggt ttctgtttcc acagcttgga
    37621 tcaagctttc ccagttgcta acctcatgtg agccaatctt ggtaatttgt gccgtttctg
    37681 gtactcctac cttggccaag gcaccttggg gcatgatatg gaactgattg gtatcaacat
    37741 ctctgacacc accctgcata aagattaaaa cccaaaaaac aacgacacct aagataaaat
    37801 tgttcatagg acctgcaaaa ttggtaatca gtttgcccca gatagtcgca ttttgatatt
    37861 gaacatctaa aggcgcaatc cgaacctcag taccatctgc ttccacaacc gttgcatcgt
    37921 gatccactgc aaatgttttt tcttcttcca gaaccaatcc tttgataaag agcttgtctt
    37981 caaaatcaaa ctgggtcacc tgcataggga gggctgtttg atccaatttt ttacctgaga
    38041 gattgatgcg tttaacctta ccatcatcag caagtgtcaa actaacaggc gttcctgtct
    38101 tgatttcagt tgtatcatca ccccaaccgg ccatgcggac atagccaccc agaggcaaga
    38161 ttcgaatggt ataggccgtt ccatccttgc caatgtgagc aaaaatttta ggtcccatac
    38221 cgatggcaaa ttcacgtact aaaatccctg atttcttggc aaagtagaag tggccgaact
    38281 cgtgcaccac tacaataatc ccgaaaacca gaataaaggt taaaattccg agcatagcgt
    38341 ttcctccgtc ttttgattaa aagagtccaa ataagtgcat gattggaaat acaagcaaca
    38401 tactatcgaa acgatccaaa acaccaccat gtccagggat aaatttccca gaatccttaa
    38461 caccaaaatg acgtttgatc gaactttcta gtaaatcacc aaattgtcca gcaatgctaa
    38521 agaaaatagc aaagactgac atcttgtaaa ttccatatgg aagagcaact gtactgtcaa
    38581 ctatcataaa gataatggtt actaaaattg ctcctaaaat accacccaag gcaccctcaa
    38641 gggttttatt aggcgatacc cttggtgcta actttcgttt cccatagttc atcccaacaa
    38701 gataggcacc actgtctgtc gcccagacga tacacaaggc taagagagcc ttgtccaaac
    38761 ctgcaacacg agcatctagt aaagcattaa atccaaagcc cacgtagaag ctcatagcaa
    38821 gagggaaaac cgcatcctca atcgtataag acttgctaaa aacggtcgtt cctaacatga
    38881 ttgaaatcaa aacactatag gcaaccacat tcccatcaac tggcaaaaaa gtcaggtaat
    38941 tctccaaggg aatggtcaat gcaaaggttg caaagagggt caagaggccc tccatcgtca
    39001 tggtctctag acctctcatc ttcaaaagtt catgcatggc tagcatggct atgattccga
    39061 ttgctatctg aagcaagagg cccccaatca ttaaaattgg taggaaaata gccagggcaa
    39121 tccctgcaaa caaggttctt ttctgtaaat cctgggtcat atttcctcct aaactcctcc
    39181 aaatcggcga tgacgacgat tataggcaag aatagcttcc tgcaaggccg cttcgtcaaa
    39241 atcaggccat aaggtgtccg taaaataaag ctcactatag gctccctgcc atggaaggaa
    39301 attgctcaaa cgtaattctc cactagtacg gataatcaag tctgggtctc gtaagtcctt
    39361 aggtaaatgc tgagtaaaga gatagttacc aatcaattcc tctgtgatgt cacctgggtt
    39421 gattttggca tctaaaacat cctgggaaat caacttaagc gcctgtgtaa tctcagcacg
    39481 tccaccatag ttaagagcaa aattaagaat caatcctgtg ttgttcttag tcaattcctc
    39541 agccttggtt aaagcttcaa aggtttgctt aggcaggcag tctgtctccc caatcatttg
    39601 aatcttaaca ttattcgcat gtagttccgg gacataatta tcataaaact ctactggcaa
    39661 gttcatgata aacttgactt cctgatctgg acgggtccag ttttccgtag aaaaagcata
    39721 gaccgtaata accttgacgc ccagtttgtt ggctgccttg gtcacggttt gcaatgcttc
    39781 catgcccgct ttgtgtccaa aaactcgcgg ttgcatacgt tttttagccc aacggccatt
    39841 gccatccatg atgatgccga tatgagcagg aacctgtgtc ggaacctcta cttccacagc
    39901 cttatctttc ttaaaaaatc caaacatgat cttattccta ttcaaaaatc tatcgtttca
    39961 ttataccata tttccccatt ttcttctatc actaagctat ttattctcag gcaccatacc
    40021 catttttcaa aaaaataagc cgcctgattg ggcgacttta tttttatagg gagattatta
    40081 tgaaaaagtt ttaggagttt aagttaaggt cttcttaact tatgaactta gtgtacactc
    40141 cctagcttaa agtttcctta agtattttta aaaatcaaat ttttccattt ctcctgccaa
    40201 tttttcttgg ataaacgtgt ttgatagagt tccattcggt cttcattttc taagaaatga
    40261 ggagttggac gaacttgaaa attcaaaata tcctccaaac cataaggtac atagagttca
    40321 aaatctgatt cttcattcaa gcgcagtcca actgccgtac accgttctgg atacttactc
    40381 atagcatcac gagaactggt ataggaagca gtgtgaggac tgtgctgatg catatagacc
    40441 tgatttttca attcccactg gtactgagga aagtcctctc gcagtttttt ctccagtaat
    40501 aaggtttcct cataagaaat atccggatca aagaaaatca cacctatatc tgtttcatga
    40561 tcaaaagggg atttgtctga caaaagattc caaatgaaat ttctgacaga acctgctgcc
    40621 aaccacgagt ctttcagacc aaggtctcgg atgatcgtca gaatggccat catatctgga
    40681 ttttctctaa aagcctctaa gatttcttgc ttatttttca ctgtattcat aacctaagtg
    40741 ctcatatgcc ttagcagtcg ccacccgtcc agaccgtgtc cgcatgataa aacctttttg
    40801 aatcaagtaa ggctcataca tatcttcaac tgtctcacgc tcttcggcga tattcacaga
    40861 aagagttcct agaccaacag gtcctccact gtacatctca atcatggtac gaaggatttt
    40921 ttgatccaca tagtccaaac cttcatggtc aacatccagc atagtcaaag ccttatcggt
    40981 aataatatca tcaattaccc cattccccat tatctgggca aaatcgcgca cgcgcttgag
    41041 gagacgattg gcaatacgag gggtcccacg actacgtagg gccaactcag atgctgcctc
    41101 atgagtgatt tccatctcaa aaatatctgc cgtccgctcg acaatttctg tcaagtcagc
    41161 atgggcataa tactccatat gacctgtaat cccaaaacgt gcccgtagcg gattggagag
    41221 cataccagcc cgagtcgtcg caccaatcaa ggtaaaaggt ggtaactcca aatgaacact
    41281 acgactaccc tcaccagccc caatcataat atctatgtag aagtcctcca tagcactata
    41341 aagcacctct tccactgaca ttggcaaacg atggatctca tcaataaaaa ggacatcccc
    41401 aggctctaac tcattcaaaa tagctaccag atctccggct ttttcaatga ctggacccga
    41461 cgtttgcttg agattgactc ccagttcatt ggcaataaca aaggccatgg tcgttttccc
    41521 gagacctgga ggcccaaata agagcacatg atccagcgct tcatcccgca tttttgcagc
    41581 ttcaataaag atttgaagct ggtccttaac cttatcctgc ccaatatatt cacgtaagta
    41641 ctgaggacgg agcgtgcgtt ctactaactc ctcgtccccc attatctcat tatctaaaat
    41701 tctactcatg gctctattat atcaaaaaac caagccacaa acaaaaaagt cactggattg
    41761 gtgcttcccg agtttagcac ttatgtggta taatattata cggcacttct acaccgccta
    41821 cgaaaggagg tgagatagcc catgatggaa ttagtactca aaactatcat cgaaccaatt
    41881 gtggtcggtg tcgttcttcg attagtcgat aaatggctaa acaaggacaa atagtgtcaa
    41941 aaaagacctc aagcttattt ggtcgtgagc ttggggtctt ttctagccta tgatatagaa
    42001 ctagtactca attccttttt attatcccat agttcacaca ttttgtcaaa gttttatatt
    42061 ttcatccatt cagcttctcc aactttagaa tctgtccaat aaagtttata agattaagtg
    42121 aaagttatcg gaaaatgatg tttaaaatag tccccaaaag cctgaaatag agcaaaaaac
    42181 tccacctggt tgggtgactc ccgagtttag cacttatgtg gtataatatt ctacggcact
    42241 gctacaccgc ttgcgaaagg aggtgagata gcccatgatg gaactaatcc ttaaaactat
    42301 catcggaccg attgtggtcg gtgtcatcct tcgcttagtc gataaatggc taaacaaaga
    42361 tagatagtgt caaaaaagac cccaagctta atgtggaagt tagcttgggg tcttttctag
    42421 tccatgatat agaactaatc cttaattcct ctccattatc ccacagttca caaaatttgt
    42481 caaaacttta catcctcagc ttctcaagct ttaaccgctt tacaacaaga ctttcaattt
    42541 taagagaaag ttagggattc tatcaatttc atagaaattt tgatttagta aacgaagaga
    42601 caatcttata tgtcactcct catttaatac gccactactg gacaagcaaa atcattatta
    42661 cagcagttcc agtccttcaa ttaacagcaa cttacaatca agttgaggac gaacttgctg
    42721 aagcgacaac cgacctattt cttagtcata ttcgctaaaa aaatccccgc caaaatctca
    42781 aaaagtcccc gccaattccc cgaccaaaat ccgaaaaata ccgaaaaata tcgaaaaatt
    42841 atttttagaa tagtccccaa aagcctgaaa tagagccaaa aaactccacc tgattgggtg
    42901 gagttaaggg agattattat aaaaaagaaa agtttaggat tt
//
LOCUS       DAVKZI010000014        42744 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKZI010000014 DAVKZI010000000
VERSION     DAVKZI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.014"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..938
                     /locus_tag="VXB18_000872"
                     /pseudo
     CDS             1..938
                     /locus_tag="VXB18_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1067..1270)
                     /locus_tag="VXB18_000873"
     CDS             complement(1067..1270)
                     /locus_tag="VXB18_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382098.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1263..2345)
                     /locus_tag="VXB18_000874"
     CDS             complement(1263..2345)
                     /locus_tag="VXB18_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0382099.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2471..3253)
                     /locus_tag="VXB18_000875"
     CDS             complement(2471..3253)
                     /locus_tag="VXB18_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0382100.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILNQEIAEEYSDVKSKADFS"
     gene            complement(3253..4596)
                     /locus_tag="VXB18_000876"
     CDS             complement(3253..4596)
                     /locus_tag="VXB18_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0382101.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLAIRQIVRKEMN"
     gene            complement(4695..6011)
                     /locus_tag="VXB18_000877"
     CDS             complement(4695..6011)
                     /locus_tag="VXB18_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0382102.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6205..7431
                     /locus_tag="VXB18_000878"
     CDS             6205..7431
                     /locus_tag="VXB18_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0382103.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILAGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7630..9204
                     /locus_tag="VXB18_000879"
     CDS             7630..9204
                     /locus_tag="VXB18_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0382104.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9468..10256
                     /gene="codY"
                     /locus_tag="VXB18_000880"
     CDS             9468..10256
                     /gene="codY"
                     /locus_tag="VXB18_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0382105.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10256..10831
                     /locus_tag="VXB18_000881"
     CDS             10256..10831
                     /locus_tag="VXB18_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0382106.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10913..10998
                     /locus_tag="VXB18_000882"
     tRNA            10913..10998
                     /locus_tag="VXB18_000882"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10947..10949,aa:Leu,seq:aag)
     gene            11281..12411
                     /gene="ugpC"
                     /locus_tag="VXB18_000883"
     CDS             11281..12411
                     /gene="ugpC"
                     /locus_tag="VXB18_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0382107.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12558..12704)
                     /locus_tag="VXB18_000884"
     CDS             complement(12558..12704)
                     /locus_tag="VXB18_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382108.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            12912..13670
                     /locus_tag="VXB18_000885"
     CDS             12912..13670
                     /locus_tag="VXB18_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0382109.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13757..14269
                     /locus_tag="VXB18_000886"
     CDS             13757..14269
                     /locus_tag="VXB18_000886"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0382110.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14451..15395
                     /locus_tag="VXB18_000887"
     CDS             14451..15395
                     /locus_tag="VXB18_000887"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0382111.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            15404..16081
                     /locus_tag="VXB18_000888"
     CDS             15404..16081
                     /locus_tag="VXB18_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0382112.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            16179..16937
                     /locus_tag="VXB18_000889"
     CDS             16179..16937
                     /locus_tag="VXB18_000889"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0382113.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16975..18479
                     /gene="lytC"
                     /locus_tag="VXB18_000890"
                     /pseudo
     CDS             16975..18479
                     /gene="lytC"
                     /locus_tag="VXB18_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            18985..19503
                     /locus_tag="VXB18_000891"
     CDS             18985..19503
                     /locus_tag="VXB18_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0382114.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            19633..20139
                     /locus_tag="VXB18_000892"
     CDS             19633..20139
                     /locus_tag="VXB18_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0382115.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAEFQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            20139..20309
                     /locus_tag="VXB18_000893"
     CDS             20139..20309
                     /locus_tag="VXB18_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382116.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAVYMTLF"
     gene            20341..21573
                     /gene="clpX"
                     /locus_tag="VXB18_000894"
     CDS             20341..21573
                     /gene="clpX"
                     /locus_tag="VXB18_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0382117.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21582..22169
                     /locus_tag="VXB18_000895"
     CDS             21582..22169
                     /locus_tag="VXB18_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0382118.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            22180..22560
                     /locus_tag="VXB18_000896"
     CDS             22180..22560
                     /locus_tag="VXB18_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0382119.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22612..23502
                     /gene="rapZ"
                     /locus_tag="VXB18_000897"
     CDS             22612..23502
                     /gene="rapZ"
                     /locus_tag="VXB18_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0382120.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23499..24476
                     /locus_tag="VXB18_000898"
     CDS             23499..24476
                     /locus_tag="VXB18_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0382121.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIVDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24473..25384
                     /gene="whiA"
                     /locus_tag="VXB18_000899"
     CDS             24473..25384
                     /gene="whiA"
                     /locus_tag="VXB18_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0382122.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25472..26598)
                     /locus_tag="VXB18_000900"
                     /pseudo
     CDS             complement(25472..26598)
                     /locus_tag="VXB18_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(26740..27120)
                     /locus_tag="VXB18_000901"
     CDS             complement(26740..27120)
                     /locus_tag="VXB18_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0382123.1"
                     /translation="MTIEELVDSHGVTLAYFDNELWQRPGVYIKEISIIFINRELSEN
                     AKKRVIYHELGHLEHSTALYKNNHTRCENEANRHMIHKLLEEELALSDDHQSFNYIQF
                     MQKHELRTVTDELMVIDEYYELIG"
     gene            complement(27141..27503)
                     /locus_tag="VXB18_000902"
     CDS             complement(27141..27503)
                     /locus_tag="VXB18_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382124.1"
                     /translation="MLSEENIMSQDTYSKSEIDLKLDKINSDTQHGFEKIDLKVDQLR
                     QEMRSGFEKIDLKFEQVDLKFDNFEKRVETMFLTQENKRLEEQAKSKKEFMYWFIGLL
                     VSTLLGILAIIVTILTTK"
     gene            complement(27624..28046)
                     /locus_tag="VXB18_000903"
     CDS             complement(27624..28046)
                     /locus_tag="VXB18_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382125.1"
                     /translation="MTNIPMKKNPFREKMTAISIVNPETAQLLGTITNFDMFPGSTSL
                     VAFLDFFNLRPETDYILSLTAHFPNGTSYPVHATRINIARQEFVLLEDGFGMATGNFS
                     FNFTIEKPSDFYFFFVLMDENGQEVDTAYSYHHFGKWG"
     gene            complement(28048..28404)
                     /locus_tag="VXB18_000904"
     CDS             complement(28048..28404)
                     /locus_tag="VXB18_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382126.1"
                     /translation="MFETFEKIKSLAKKQGISLNTLEDRVGLGKNYIYSLKNKKTPSA
                     EHISKIADYFNVSTDYLLGRTDNPAIAGDDTIAGYTSDDLRKMAENAKTFDGKPLTEE
                     DIDAIQNIIEIYLRGR"
     gene            complement(28821..29060)
                     /locus_tag="VXB18_000905"
     CDS             complement(28821..29060)
                     /locus_tag="VXB18_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382127.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            29125..29316
                     /locus_tag="VXB18_000906"
     CDS             29125..29316
                     /locus_tag="VXB18_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0382128.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            complement(29430..29651)
                     /locus_tag="VXB18_000907"
     CDS             complement(29430..29651)
                     /locus_tag="VXB18_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382129.1"
                     /translation="MSKLTKEDVLQVSQDIINDAIPVIKDMLDEVFEKYPIDIEIREA
                     IFYSVLVAHKLSTETTVSLLTQLVNAQEN"
     gene            29769..29912
                     /locus_tag="VXB18_000908"
     CDS             29769..29912
                     /locus_tag="VXB18_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382130.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            29983..30255
                     /locus_tag="VXB18_000909"
     CDS             29983..30255
                     /locus_tag="VXB18_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382131.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            30252..30446
                     /locus_tag="VXB18_000910"
     CDS             30252..30446
                     /locus_tag="VXB18_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382132.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            30443..30634
                     /locus_tag="VXB18_000911"
     CDS             30443..30634
                     /locus_tag="VXB18_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382133.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            30646..30987
                     /locus_tag="VXB18_000912"
     CDS             30646..30987
                     /locus_tag="VXB18_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382134.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDTRREWVDMLTRAAEKETVSNVMRLLIK
                     EANKLMKEVTK"
     gene            30988..31218
                     /locus_tag="VXB18_000913"
     CDS             30988..31218
                     /locus_tag="VXB18_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382135.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            31232..31954
                     /locus_tag="VXB18_000914"
     CDS             31232..31954
                     /locus_tag="VXB18_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0382136.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPLNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEEHHGPIPKGHSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            31947..32429
                     /locus_tag="VXB18_000915"
     CDS             31947..32429
                     /locus_tag="VXB18_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0382137.1"
                     /translation="MASLYELTGQFLTVYQMDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            32429..32788
                     /locus_tag="VXB18_000916"
     CDS             32429..32788
                     /locus_tag="VXB18_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382138.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            32788..33273
                     /locus_tag="VXB18_000917"
     CDS             32788..33273
                     /locus_tag="VXB18_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382139.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            33236..34429
                     /locus_tag="VXB18_000918"
     CDS             33236..34429
                     /locus_tag="VXB18_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0382140.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            34448..34765
                     /locus_tag="VXB18_000919"
     CDS             34448..34765
                     /locus_tag="VXB18_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382141.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            34765..35592
                     /locus_tag="VXB18_000920"
     CDS             34765..35592
                     /locus_tag="VXB18_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0382142.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            35612..36118
                     /locus_tag="VXB18_000921"
     CDS             35612..36118
                     /locus_tag="VXB18_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382143.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDDDDLPF"
     gene            36291..37112
                     /locus_tag="VXB18_000922"
                     /pseudo
     CDS             36291..37112
                     /locus_tag="VXB18_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
     gene            37115..38458
                     /locus_tag="VXB18_000923"
     CDS             37115..38458
                     /locus_tag="VXB18_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0382144.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERAAEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            38752..38904
                     /locus_tag="VXB18_000924"
     CDS             38752..38904
                     /locus_tag="VXB18_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382145.1"
                     /translation="MSYTVTLYFDNMVDETHLFKKKGDAAKCKAQLESKYRGDRMYKV
                     KMEEME"
     gene            38904..39242
                     /locus_tag="VXB18_000925"
     CDS             38904..39242
                     /locus_tag="VXB18_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382146.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            39393..39707
                     /locus_tag="VXB18_000926"
     CDS             39393..39707
                     /locus_tag="VXB18_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382147.1"
                     /translation="MEELKKKVNAVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYSPSMAQVVIAVYLIYG
                     GN"
     gene            39709..40215
                     /locus_tag="VXB18_000927"
     CDS             39709..40215
                     /locus_tag="VXB18_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0382148.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLNGYEVEK
                     EKRYFVKIKGNIKENMLVYGEFLKRYFFTKSFSLDDVIYSHTRKELEDANFGWVFDCS
                     GIEIEEVE"
     gene            40520..40915
                     /locus_tag="VXB18_000928"
     CDS             40520..40915
                     /locus_tag="VXB18_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382149.1"
                     /translation="MIPKFRVWHYELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPSIYLKG
                     LLNGYAWTEDEEIIDNVYENPELLEVTHE"
     gene            40908..41087
                     /locus_tag="VXB18_000929"
     CDS             40908..41087
                     /locus_tag="VXB18_000929"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382150.1"
                     /translation="MNKRQRKKKILNGLNKEERYHRTHCPVCDSEAGLFDRYFNTYGF
                     CSEYCGYEYYGISRL"
     gene            41108..41422
                     /locus_tag="VXB18_000930"
     CDS             41108..41422
                     /locus_tag="VXB18_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382151.1"
                     /translation="MTLFDEVQQLSSESHAKWFERYFEKYNLEQKLKTSAQKGYTGYL
                     INVWSVRDEYLRNRLGDEITFEALRELLGAGFTVKYKLYLSKNIFTGQDFVSNKKIHI
                     TW"
     gene            41497..41958
                     /locus_tag="VXB18_000931"
     CDS             41497..41958
                     /locus_tag="VXB18_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0382152.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWSDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLQLGRMINRLKNPKHRTILRMTYINK
                     MYVDDICDSMRGISSPTYYRLKKQAVKELDIILSELIVNDSNCTGMKSKIC"
     gene            41983..42065
                     /locus_tag="VXB18_000932"
     tRNA            41983..42065
                     /locus_tag="VXB18_000932"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42014..42016,aa:Tyr,seq:gta)
     gene            42314..>42744
                     /locus_tag="VXB18_000933"
     CDS             42314..>42744
                     /locus_tag="VXB18_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0382153.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEA"
BASE COUNT        13592 a         7480 c         9377 g        12295 t
ORIGIN      
        1 ttcaatcaga aaatgagtac ctgagagcgg agaatgccat cctaaaaaag ttaagagaac
       61 tccgattgaa ggaggaaaaa gagaaagaag aaagacagaa attgttcaag aattaatgac
      121 tgagttttcg ttagatcttc ttctaaaagc cattaaacta gctcgttgga cctactacta
      181 tcacttgaaa cagctagata aaccagataa ggaccaagag cttaaagctg aaattcaatc
      241 catctttatc gaacacaagg gaaattatgc ttatcgtcga atttatttag aactaagaaa
      301 tcgtggttat ctggtaaatc ataaaagagt tcaagacttg atgaaagtac tcaatttaca
      361 agctaaaatg tgacagaaac gaaaataaag gagacgttgg taagaaggca gagaatctca
      421 ttcaaggcca atttgaaggc tctaaaacaa tggaaaagtg ctacacagat gtgacagaat
      481 ttgccattcc agcaagtact caaaagcttt acttatcacc agttttagat ggctttaata
      541 gcgaaattat cgcctataat ctttcaactt cacccaactt agaacaagta caaacaatgt
      601 tggaacaggc ctttacagag aaatactatg agaatacgat tctccatagt gaccaaggct
      661 ggcaatacca acacgattct tatcatcagt ttcttgaggg taagggaatt caagcatcca
      721 tgtcacgcaa gggaaacagc caagacaacg gtatgatgga gtccttcttt gggattctga
      781 aatcggaaat gttttatggc tatgagaaaa catttaaatc acttaatcaa ttggaacaag
      841 ctattgtaga ctatattgat tactacaaca ataaacgaat taaggtaaaa ctaaaaggac
      901 ttagccttgt gcaatacaga actaaatcct tcggataaat taattgtcta acttttgggg
      961 ggcagtacat attcaacacc tgatactatg cgttttattg tgggaagatt ttcctcattt
     1021 tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa tcaattatca
     1081 tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg agagcaccct
     1141 cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta gcataatagc
     1201 agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag gggctatata
     1261 gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa gccatccttg
     1321 gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata gatacctggt
     1381 tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat gatagatggg
     1441 aattcatgga catccatacc gataccatgc ccgagacggt ggttgaagta ctcaccataa
     1501 ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt cacacctggc
     1561 ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat atctttcttg
     1621 aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata gccattgacc
     1681 agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc tgctggaatg
     1741 ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct catttcgtaa
     1801 ccttcacgtt tcatggcaaa gtcaatttgt gcgatgatat ctgtctcagt cttatcaaga
     1861 gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc aaccatcatt
     1921 ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg agtgaggttg
     1981 tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa gatgagattg
     2041 tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt gattttttgc
     2101 catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct acttgcacgt
     2161 tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac aaagaggaac
     2221 atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt gacggggtca
     2281 gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg ttgtaattta
     2341 gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga aaatgcaagg
     2401 gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct ttgatatcat
     2461 tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct tcagcgattt
     2521 cttggttgag gatatcctca taggcaggga gttggatatc ctgaccatat ttcttcttga
     2581 gggcagtagt aactaggcga taagccagat tggcattacg agagaggata ggcccgtgga
     2641 agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct tcgttgtttc
     2701 catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag gtacggcctt
     2761 ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc ttgatgtcac
     2821 cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct agcccttcga
     2881 tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca ccgcagatag
     2941 ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta gcaggtaggt
     3001 cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg atgtcgtagt
     3061 gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg gctcccagtt
     3121 tttcagccac atacttgagc atgaggatgt ttccattgtc cccgtaggta ttcatgagat
     3181 ttccgtagag gtgggcaatg ttgagctgat aggggtaatt accatctttt gaggaaagtg
     3241 aagtataaac cattagttca tctcctttct aacaatctga cgaatagcca gcagttcacg
     3301 aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt cttgattctc
     3361 aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag ctggatagcc
     3421 agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt tgatttcagg
     3481 aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag tgtcaattcc
     3541 atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg ctagtttgat
     3601 catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg tacattcctt
     3661 gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt caaatccctg
     3721 tttgatgagt tgcgaatcgg cacctaggaa acgggcgatg gccacagcag ctagggcgtt
     3781 atatatatta tagagcccgc cgatttggat accgtattct tggccgtcta tgacaaagcg
     3841 agagcgattg ttggtcaact caaccaattt tgtcaaacga tagtcgagat caggacgttt
     3901 acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat gctcatattt
     3961 gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag ccagttgggc
     4021 tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag ttggcttgta
     4081 gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaactttcc gaatggcatc
     4141 caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt cacggaagat
     4201 attagtaatg acaaaaagac taggctggat atagtcacag atacgagata gactggcttc
     4261 gtcaatttcg aggacggcaa tattttttcc agttttagaa gatttggctg ttaggaaggt
     4321 tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt gaccataaac
     4381 ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg ttccagtgac
     4441 aacgacaatc tcgtagttct tagctaggtt ttgtaaaata tctttatcaa attgaagggc
     4501 gactttacct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt gggaagaacg
     4561 cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc acaaaagagg
     4621 gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc tgtcagttaa
     4681 gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa ggttgggtga
     4741 gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc aacagtaatg
     4801 atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat ttcttttgtt
     4861 tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg accacgaggc
     4921 atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc tgcttggctt
     4981 tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg cacattgaga
     5041 cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac acggaagtca
     5101 tcaagtgaaa tgtaagtaaa ttgaagacca ccgttgacat ctccaactgc aaagacacca
     5161 ggaacgtttg tttgacagtg tttatctact ttaatagcgc cacgttcagt tagttcaata
     5221 tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc gtagagaagg
     5281 gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc gtcgttttta
     5341 atttcagtag tatggatatt ttgaagcaat tcaataccgt cttcttccat gtattgttta
     5401 gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc atctaggact
     5461 gtgaccttgc ttccaagttt gttgtaaagg ccggcaaatt caagaccgat atttccgcca
     5521 ccaaggactc caagtttttc aggcaattta tccaagcttt ggatacctgt tgagtcaaag
     5581 acgtttttgc ttgtagcaag tccagggatt ggcaagacgt ttgaaacagc accagtgttg
     5641 atgacgatag tttcagcagt caattcttgt ttttcatcac cagcttggat ttcgatgact
     5701 ttatttgaaa ggaagtgagc ttcagcatca aagatatcga cgccagtacc agcaacagtc
     5761 gtatagtttt taccgttgag gcgaccagtg atcgtgtttt tggtagcaat gacttcttca
     5821 aaagacaagt ctttctcagc agcaaccagc aaagttttag ttgggataca accgatgttg
     5881 atacaagttc caccgtacat agctttgcta cgttcaacga gggcaacttt tttgccagct
     5941 gaagccaatt taccagctag tgttttacca gctttaccaa atccgataac gattaaatca
     6001 taagttaaca tttagaattc ctcctattcg catttcattc tagcacaaga aaaaaacttt
     6061 tgcacaattc tgctacgaaa aagacagaaa aagataaaaa cgctttccag acaaaaaact
     6121 agtaattttt taacaagctt gataaactaa aatcctatct atttttatat aagatagaat
     6181 aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc ctttgctggg
     6241 gtcattttac acttaatgct gggttcgact tatgcctgga gtgtttatcg taaccctatt
     6301 attgaaaaaa cgggatggga tcaggcttct gttgccttcg cctttagtct agcaatcttt
     6361 tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg tccgaaagtc
     6421 atgggaagtc tatctgcttt tctatacgca ggtggaaata tcttagcagg atttgcaata
     6481 gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg gcttggtttg
     6541 ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga taaacgtggt
     6601 ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac tagtcccata
     6661 gcgcaacacc tcatcgcagg ggtagggatt gtagaaactt tttatatttt aggagcaagt
     6721 tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga gcaagagctt
     6781 gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg aatggctgca
     6841 aatcaggctc taaaaagcaa tcggttttat atgctttgga ttattttctt tatcaacata
     6901 gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat ggctggcttg
     6961 tctacaagtc atgcagcagt aatggtgggt gttttgggga ttttcaatgg atttggtcgc
     7021 ttgctctggg cgagtttgtc tgactatatc ggtcgccctc taacctttag tatattactg
     7081 cttgtcaatc ttttcttttc tctctcactt tggctcttta cagattccgt tttatttgta
     7141 gttgctatgt ctattttgat gacttgctat ggagctggtt tttctttgat tccagcttat
     7201 ctcagtgata tttttggaac caaggaattg gccgctctgc atggttatat tttaacagct
     7261 tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa aatggctcat
     7321 tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt ggctttgtct
     7381 tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg attttctgta
     7441 gaaatggggc tatcttttgc tctggtcttg tgttatacta gataggttgc aaagaaaaca
     7501 gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata tgaaaatacg
     7561 tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac ctttagaaag
     7621 aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctagc agaaattgaa
     7681 aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt ggcccttgaa
     7741 ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc ctttggcttg
     7801 cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttggt catcgctcca
     7861 actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg tagtaaggga
     7921 gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa ggctcttaaa
     7981 tctggtgccc atatcgtggt gggaactcca ggtcgcctct tggacttgat taaacgcaag
     8041 gccttgaaat tacaagacat tgaaaccctt atccttgacg aagcggatga aatgcttaac
     8101 atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa ccgtcaaact
     8161 ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca gtttatgaaa
     8221 gcccctgaac atgtcaagat tgcggctaag gaattgacaa cagaattggt tgaccagtac
     8281 tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat ggatgtggca
     8341 caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga attgactcgt
     8401 ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga ccaaaacaaa
     8461 cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt tgcgacagac
     8521 gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta cgatattcca
     8581 caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg taagtcaggt
     8641 caatctatta cttttgtttc tccaaacgaa atgggttacc ttcaaatcat tgaaaacttg
     8701 actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt ccaatcaaaa
     8761 aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat tcgtgccaac
     8821 tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc agaagaattg
     8881 gcaatgtata tcttgagtct gacagtccaa gatccagata gccttccaga agtggagatt
     8941 gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg taaagctaag
     9001 ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg tggcaatggt
     9061 cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa ggaaaaacgt
     9121 taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac aggctttgtt
     9181 attcgtaaca agggcgataa ataagaaaaa gcggttcaaa atgaatcgct tttttatata
     9241 aggagaccga atgtgaaaag acaaataaaa ttattatatt atcttttata atgttatgat
     9301 acacaaaaat aggcaacttg tcaatagaaa aggaacaatt taattaaaaa tattctggtt
     9361 tttaattaaa ttgtaagtca atgcaagtca ataaggaatt ttcagataat tattgaaaaa
     9421 gagacgtttt tatgttataa tgatagcgat taaattcgag gtgaaaaatg gcacatttat
     9481 tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc agaggagcag ttgcaggatg
     9541 agcttcctta caacgctatt acgcgtcagt tagcggatat tattcattgc aatgcctgca
     9601 ttatcaatag taagggacgt ctgcttggct attttatgcg ttataaaaca aatacagatc
     9661 gcgtagagca attcttccaa actaagattt tcccagatga ctacgttcaa ggggctaata
     9721 tgatttacga aacagaagca aacttgcctg ttgagcatga tatgagtatt ttccctgttg
     9781 agagtagaga tgattttcca gatggcttga cgactattgc accgattcat gtatcgggga
     9841 ttcgccttgg ttctttgatt atttggcgta atgataaaaa attcgaagat gaggacttgg
     9901 ttcttgttga gattgccagt accgttgttg ggattcagct tcttaacttc caacgtgaag
     9961 aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat ggcggtcaat accctttctt
    10021 actccgaact ccgtgctgtt tcagcaattt taggggaatt aaatggaaat gaagggaagt
    10081 tgactgcgtc agtgattgca gatcgtatcg gaatcactcg ctctgtgatt gtcaatgctc
    10141 ttcgtaaact tgagtctgcg gggattattg aaagtcgctc acttggaatg aagggaacct
    10201 atcttaaggt cttgatttca gatatttttg aagaagtgaa gaaaagagat tactaatgac
    10261 aaaggcttta atttcgattg attatacaga agattttgtt gctgatagtg ggaaactaac
    10321 agcaggtgct ccagctcagg cgatttcgga tgccatcagc aaggtaactc gattagcttt
    10381 tgaacgagga gattatatct tctttactat tgatgctcat gaagaaaacg attgtttcca
    10441 tccggaaagt aagttatttc ctcctcataa tctgattggg acgagtggac ggaatttata
    10501 tggagatttg gggatctttt atcaagagca tggttcagac agtcgtgtct tttggatgga
    10561 taaacgccat tactcagctt tttcagggac tgacctagat attcgtttga gagagcgtag
    10621 agtgtctacc gttatcttaa caggtgtctt gacggatatc tgtgtcctac atacagctat
    10681 agatgcctat aatctaggat atgacatcga gattgttaaa ccagctgttg cttccatctg
    10741 gcctgaaaat catcaatttg ccctaggtca tttcaaaaat acactcggag ctaagttagt
    10801 agatgaaaat ctaaatgaac tttctgagta acctggttgg tgaaaatgaa aaaatttgaa
    10861 aaaaagtgtt gacaagcatc ccaaaagttg atatactagt aaagtaatcg atgcggggat
    10921 ggcggaattg gcagacgcgc aggactaagg atcctgtgac cgctttaggt cgtgagggtt
    10981 caagtccctc tctccgcata ggaaaagagc tagctaaagc tagctctttt gtatttctct
    11041 aaaaaattag aatccagtca aatgtagtgg agaatcagcg aaaatatggg aaaactgatc
    11101 cttgtttctg cttttgtcat agaagaataa taaagattat cttcttcaaa ttctccgata
    11161 ttctctaaag ttttgtgcaa gttgcacaga acttttttat ttttttggtc atcttgccat
    11221 agaaatataa agcgttttca tctataatat aattatcaaa agacaaaagg agttcacctc
    11281 atggtagaat tgaatcttaa aaatatttac aaaaaatatc caaacagcga acactattca
    11341 gttgaagatt tcaacttgaa catcaaagat aaagaattta tcgttttcgt aggaccttca
    11401 ggatgtggta aatcaactac actccgtatg attgctggtc ttgaagacat tacagaaggt
    11461 actgcatcta tcgatggcgt ggttgtcaac gacgtagctc caaaagaccg tgatatcgcc
    11521 atggtattcc aaaactacgc tctttaccca cacatgactg tttatgacaa catggctttc
    11581 ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca aacgtgttca agaagcagct
    11641 gaaatacttg gattgaaaga attcttggaa cgtaaaccag ctgacctttc aggtggtcaa
    11701 cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg cgaaagtatt cttgatggac
    11761 gaacctttgt caaacttgga tgccaaactt cgtgtatcaa tgcgtgctga aatcgctaaa
    11821 attcaccgtc gtatcggagc tacaactatc tatgtaactc acgaccaaac agaagcgatg
    11881 acacttgcag accgtatcgt tattatgtca gctactaaga accctgctgg tacaggtact
    11941 atcggacgtg tagaacaaat cggtactcct caagaagttt acaaaaatcc agttaacaaa
    12001 ttcgttgcag gattcatcgg aagcccagct atgaacttca tcaacgtgaa attggttggt
    12061 agcgaaattg tttctgacgg tttccgtttg aaagtgccag aaggagcatt gaaagttctt
    12121 cgtgaaaaag gctacgaagg aaaagaattg atctttggta tccgtccaga agacgtgaat
    12181 gcagaacctg ctttccttga aacattccca gactgtgttg taaaagcgac tatctctgta
    12241 tcagaactgc ttggttcaga atctcacctt tactgccaag ttggtaaaga cgagtttgtt
    12301 gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa cagttgagct tggatttgac
    12361 ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa caatctacta aaataaataa
    12421 aattcaaagc actacaagaa aagatatctc tttatcaatt gtagtggaga gatatcagtt
    12481 aatctaggga gagaaacaaa atgcttctct cctttttgct agggaagtca tattatgcat
    12541 ctatattgtg atgctcttta atactcttcg aaaatctctt caaaccacgt caacgtcgcc
    12601 ttgccgtacg tatgattact gacttcgtca gttttatctg caacctcaaa gctgtacttt
    12661 gagcagctta cggctagttt cctagtttgc tctttgattt ccattgagta ttatttgtgg
    12721 gtaccatcta caagtgaagc tatatgcgta aactacgtga gcaattgaat tcgaactaga
    12781 gaggtaataa taaatttatg ctatagttat ggtgacttgt atgcttttga ttctagttta
    12841 tcaaataata gattagaatt gtcagataat atcattttgt gttataatga agaaaaaaca
    12901 gaggtgttca aatgtcagaa gcaggtcata agtttttagc aaaattgggg aaaaaacgct
    12961 tacgtccagg tggaaagcgt gccacagatt ggttaattgc agaaggagga ttttcaaaag
    13021 aaaagagaat actagaggtt gcgtgtaata ggggaactac agcaattgag ttggcacagc
    13081 gttttggttg caagataact gctgttgata tggatgctca agctttagaa gtggctaaaa
    13141 aatctgctgg aacggcaggt gttgctcatt taatcagttt tgaaagagca aatgcaatga
    13201 aacttcctta tcaagatgct agttttgata ttgttataaa tgaagctatg ctgactatgc
    13261 aagccgatca agctaagaaa aaatgtgtaa tggaatatct aagggtatta aaacctggag
    13321 gtcttctctt gacacatgat gtgcttctta aggaagctaa agagtctatc agacaggaat
    13381 tatcacaagc aattcatgta aatgtaggtc ctttaactca agatggttgg gaacaggtga
    13441 tgatagaatc aggttattgt gatgtgaaag cattgactgg tgaaatgaca ttaatgaaat
    13501 tatcgggtat gatttatgac gaaggtttgc taggaacttt gaaaatttgt gtaaatgctt
    13561 gtaaaaagga gaatagaaag cagtttttaa ctatgtataa aatgtttgct aagaataaac
    13621 agaaattggg ctttattgcg atggctagtt ataaatcgtc aaaacgttag ataattattg
    13681 aagttaactt ttcctttttt ctttcttaaa aaatatgcta taatagagag taaaaaactt
    13741 tgaaagaaag aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa
    13801 ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta
    13861 cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc
    13921 tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc
    13981 gcctgttcgt aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga
    14041 gtacggtgtc gatactttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct
    14101 tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga
    14161 aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg
    14221 ccgtgaaaaa attggtgact acgactacaa agttcttatg cattattaat gaaaacagtc
    14281 cctagggctg ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa
    14341 ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg
    14401 tcttcaaaca tatgcaatta ttcctgaaag agtacagtta ggagagggtt atgccgattc
    14461 gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg
    14521 atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca
    14581 tgccacagaa aatggtcaca gagacccagt tgttgcgcca cttggctaat acacccctac
    14641 aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc
    14701 acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga
    14761 tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat
    14821 ttagacagat gcttgagtgg tctaagactc atgtctattc gacccttcat atctgttggg
    14881 gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc
    14941 tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg
    15001 atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa
    15061 acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca
    15121 gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg
    15181 caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact
    15241 ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct
    15301 ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgac tggagaaaga
    15361 tagaagatga tgcatctgca tataggtatt tataagagga attatgacat atttagacgc
    15421 ttttaaatca ggtaccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt
    15481 tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt
    15541 agaagaaata tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa
    15601 ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa
    15661 tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt
    15721 tggagcagtt cattcaagtt cagaccagct aacaccacaa aaccagctca aggatttggt
    15781 ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac
    15841 caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc
    15901 tgttttgaac ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca
    15961 tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa
    16021 tcctcagttg acacaggtat ctgcagattt cataaatgcc atggatctct ggaaggatta
    16081 atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag
    16141 aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg
    16201 ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg
    16261 catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt
    16321 tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct
    16381 actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg
    16441 gtactgacta cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgatg
    16501 aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgctccca atcatctgtt
    16561 gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag
    16621 tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg
    16681 agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt
    16741 gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc
    16801 gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag
    16861 acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc
    16921 ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct
    16981 gttacatttt ttataggaga gaaagattga aaacaaaaat tggattagca agtatctgtt
    17041 tactaggctt ggcaactagt catgtcgctg caaatgaaac tgaagtagca aaaacttcgc
    17101 aggatacaac gacagcttca agtagttcag agcaaaatca gtcttctaat aaaacgcaaa
    17161 cgagcgcaga agtacagact aatgctgctg cccactggga tggggattat tatgtaaagg
    17221 atgatggttc taaagctcaa agtgaatgga tttttgacaa ctactataag gcttggtttt
    17281 atattaattc agatggtcgt tactcgcaga atgaatggca tggaaattac tacctgaaat
    17341 caggtggata tatggcccaa aacgagtgga tctatgacag taattacaag agttggtttt
    17401 atctcaagtc agatggggct tatgctcatc aagaatggca attgattgga aataagtggt
    17461 actacttcaa gaagtggggt tacatggcta aaagccaatg gcaaggaagt tatttcttga
    17521 atggtcaagg agctatgatg caaaatgaat ggctctatga tccagcctat tctgcttatt
    17581 tttatctaaa atccgatgga acttatgcta accaagagtg gcaaaaagtg ggcggcaaat
    17641 ggtactattt caagaagtgg ggctatatgg ctcggaatga gtggcaaggc aactactatt
    17701 tgactggaag tggtgccatg gcgactgacg aagtgattat ggatggtact cgctatatct
    17761 ttgcggcctc tggtgagctc aaagaaaaga aagatttgaa tgtcggctgg gttcacagag
    17821 atggtaaacg ctatttcttt aataatagag aagaacaagt gggaaccgaa catgctaaga
    17881 aaatcattga tattagtgag cacaatggtc gtatcaatga ttggaaaaag gttattgatg
    17941 agaacgaggt ggatggtgtc attgttcgtc taggttatag cggtaaagaa gacaaggaat
    18001 tggcgcataa cattaaggag ttaaaccgtc tgggaattcc ttatggtgtc tatctctata
    18061 cctatgctga aaatgagacc gatgctgaga atgacgctaa acagaccatt gaacttataa
    18121 agaaatacaa tatgaacctg tcttacccta tctattatga tgttgagaac tgggaatatg
    18181 taaataagag caagagagct ccaagtgata cagatacttg ggttaaaatc atcaacaagt
    18241 acatggacac gatgaagcag gcgggttatc aaaatgtgta tgtctatagc tatcgtagtt
    18301 tattacagac gcgtttaaaa cacccagata ttttaaaaca tgtaaactgg gtagcggcct
    18361 atacgaatgc tttagaatgg gaaaaccctt attattcagg agaaaaaggt tggcaatata
    18421 cctcttctga atacatgaaa ggaatccaag ggcgcgtaga tgtcagcgtt tggtattaag
    18481 cgatgatttg aaagagggat gtgatagtag caccctcttt ttctttgttt tatgatagtt
    18541 catcctcgag taaattcaag atcttgctcg gaaatgaagc ttatgaagct tatatagtag
    18601 attgaatata gataaagacc ttgtgattgg taaaacattt tagaaattca tttacctttc
    18661 ctaatcgact tggtttcatc ttatttcaat ctattatagt attggggaat ttcttcaaac
    18721 cacatcagct tggtcagttc tacctgcgac ctcaaaactt gtgctttggt caagctgggt
    18781 ttagtttcct agtttgctga tggatttcca ttgactataa gcatccaacc ctctttttgt
    18841 cttctaaaga attcttaaat tatcagtcta ttgcaacttt tctcatataa gttctttgtc
    18901 ttgctattgg ttttccttag tagtatacta aggtagtaat cattaagaag tggttacaaa
    18961 aaataatgaa tgaggtaaaa taaaatggta gaattgaaaa aagaagcagc aaaagatgtc
    19021 gcaacattga caaaagcagc gccagtagca ttggcaaaaa caaaggaagt cttgaaccaa
    19081 gctgttgctg atttgtatgt agctcacgtt gctttgcacc aagtgcactg gtatatgcat
    19141 ggtcgtggtt tccttgtatg gcatccaaaa atggatgagt acatggaagc tcttgacggt
    19201 caattggatg aaatcagcga acgcttgatt acactcggtg gaagcccatt ctctactttg
    19261 acagagttcc ttcaaaacag tgaaatcgaa gaagaagctg gtgaataccg taatgttgaa
    19321 gaaagcttgg aacgtgttct agctatttat cgctacctca tcactctttt ccaaaaagcg
    19381 ttggatgtga ctgacgaaga aggcgatgat gttacaaacg atatttttgt tggtgctaag
    19441 gctgaacttg agaaaacagt ttggatgctt gccgcagaac ttggacaagc acctggtttg
    19501 taagaaacaa gacaacatag ataaatctgt aggaaatttc ttacagattt tttctatttt
    19561 gtaagctatt ccaaaccagt ctttttttga gttttttgat aaaatagtac tatcagtgaa
    19621 aaggatggaa gcatgactaa gaaaatcgta gctatttggg cccaggatga agagggtgtg
    19681 attggtaagg acaatcgtct gccttggcat ttgccagcag aatttcagca ctttaaagaa
    19741 acaactctga atcatgctat cttgatgggg cgggtaacct ttgatggaat ggggcgtcgc
    19801 ttgcttccaa aacgggagac cctgattttg acgcgtaatc cggaagaaaa gatagatggg
    19861 gttgctactt ttcaggacgt ccagtctgtt cttgactggt atcaggctca agaaaagaat
    19921 ctctacatta tcggtgggaa gcaaattttt caggcttttg aagcttacct tgatgaagtg
    19981 attgtcactc acattcatgc tcgggtggaa ggagatacct atttccctga agagcttgac
    20041 ttgtctcttt ttgagacagt ttcaagcaaa ttttacgcca aagatgagaa gaatccttat
    20101 gattttacca tccaataccg caagagaaag gaagtttaat ggaacggagt ttatttggtc
    20161 tattcacggc ttttctgtgt ttcatctgct ttctggcagg agcacaagct tttcgtaaaa
    20221 agcgttacgg gctttctatc ctcctttggt taaatgcctt taccaatctg gtcaatagta
    20281 ttcatgctgt ttacatgacc ttattttaga tagaatgaca gtatagaatg gaaggaaatc
    20341 atgtctacaa atagaaaaaa tgatatgatg gtttattgct cattttgtgg caaaaaccaa
    20401 gaagaagtac aaaaaataat tgctggcaac aatgctttta tttgtaatga atgcgtggag
    20461 ttagctcagg aaatcattcg agaagaattg gttgaggaag tcttggcaga cttgtctgag
    20521 gtgccaaaac caattgaact cctccatatc ttgaaccact atgtaattgg tcaagatcgt
    20581 gccaagcgtg ccttggcagt ggcggtttat aaccactaca aacgcatcaa tttccacgat
    20641 acacgcgaag agtcagaaga tgtggatttg cagaagtcaa acattttgat gattggccca
    20701 actggttcag ggaaaacttt ccttgcccag accttggcta agagcttaaa tgtacctttt
    20761 gctattgcgg atgcgacagc tctgacggag gctggttatg tgggtgagga tgtggaaaat
    20821 atactcctca aactcttgca ggttgctgac tttaacatcg aacgtgcaga gcgtggcatt
    20881 atctatgtgg atgaaattga caagattgcc aagaagagtg agaatgtgtc tatcacacgt
    20941 gatgtttctg gtgaaggggt gcaacaagcc cttctcaaga ttatcgaggg aactgttgct
    21001 agcgtaccgc ctcaaggtgg acgcaaacat ccacaacaag agatgattca agtggataca
    21061 aaaaatatcc tcttcatcgt gggtggtgct tttgatggta ttgaagaaat tgtcaaacaa
    21121 cgtctgggtg aaaaagtcat cggatttggt caaaacaata aggcgattga cgaaaacagc
    21181 tcatacatgc aagaaatcat cgctgaagac attcaaaaat ttggtattat ccctgagttg
    21241 attggacgct tgcctgtttt tgcggctctt gagcaattga ccgttgatga cttggttcgc
    21301 atcttgaaag agccaagaaa tgccttggtg aaacaatacc aaactttgct ttcttatgat
    21361 gatgttgagt tggaatttga cgacgaagcc cttcaagaga ttgctaataa agcaatcgaa
    21421 cggaagacag gggcgcgtgg acttcgctcc attatcgaag aaaccatgct agatgttatg
    21481 tttgaggtgc cgagtcagga aaatgtgaaa ttggttcgca tcactaaaga aactgtcgat
    21541 ggaacggata aaccgatcct agaaacagcc tagaggtgac tatggaactt aatacacaca
    21601 atgctgaaat cttgctcagt gcagctaata agtcccacta tccgcaggat gaactgccag
    21661 agattgccct agcagggcgt tcaaatgttg gtaaatccag ctttatcaac actatgttga
    21721 accgtaagaa tctcgcccgt acatcaggaa aacctggtaa aacccagctc ctgaactttt
    21781 ttaacattga tgacaagatg cgctttgtgg atgtgcctgg ttatggctat gctcgtgttt
    21841 ctaaaaagga acgtgaaaag tgggggtgca tgattgagga gtacttaacg actcgggaaa
    21901 atctccgtgc ggttgtcagt ctagttgacc ttcgtcatga cccgtcagca gatgatgtgc
    21961 agatgtacga atttctcaag tattatgaga ttccagtcat cattgtggcg accaaggcgg
    22021 acaagattcc tcgtggtaaa tggaacaagc atgaatcagc aatcaaaaag aaattaaact
    22081 ttgacccaag tgacgatttc atcctctttt catctgtcag caaggcaggg atggatgagg
    22141 cttgggatgc aatcttagaa aaattgtgag gaaaagaaaa tggcaaaaac aattcataca
    22201 gataaggccc caaaggctat cggaccctat gttcaaggaa aaatcgttgg caaccttttg
    22261 tttgctagcg gtcaagttcc cctatcccct gaaactgggg aaattgtagg agagaatatc
    22321 caagaacaga cagagcaagt cttgaaaaac atcggtgcta ttttggcaga agcaggaaca
    22381 gactttgacc atgttgtcaa aacaacttgt ttcttgagcg atatgaacga ctttgttcct
    22441 tttaatgagg tttaccaaac ggccttcaaa gaggaattcc cagctcgttc agctgtggag
    22501 gtagctcgtc ttcctcgtga tgtaaaagtc gaaattgaag tcatcgcaga gattggataa
    22561 gctagttgaa gtttggtgtt gccaaacttc ttttgatata aggagaaaaa gatgacaaag
    22621 aaacaacttc acttggtgat tgtgacaggg atgagtggcg cagggaaaac tgtagccatt
    22681 cagtccttcg aggatctagg ttatttcacc attgataata tgccgccagc tctcttgcct
    22741 aagtttttgc agctggttga aattaaggaa gacaatccta agttggcctt ggtagtggat
    22801 atgcgtagcc gttctttctt ttcagagatt caagctgttt tggatgagtt ggaaaatcaa
    22861 gatggtttgg atttcaaaat cctctttttg gatgcggctg ataaggaatt ggtcgctcgt
    22921 tacaaggaaa ccagacggag tcacccacta gcagcagacg gtcgtatttt agatggaatc
    22981 aagttggaac gtgaactctt ggcacctttg aaaaatatga gccaaaatgt ggtggatacg
    23041 actgaactca ctccacgtga gctgcgcaaa acccttgcag agcagttttc agaccaagaa
    23101 caagctcagt ctttccgtat cgaagtcatg tctttcggat ttaagtatgg aatcccgatt
    23161 gatgcggact tggtctttga tgtccgtttc ttgccaaatc cctattattt accagaactg
    23221 agaaaccaaa cgggtgtgga tgaacctgtt tatgattatg tcatgaacca tcctgagtca
    23281 gaagactttt atcaacattt attggccttg attgagccga ttctgccaag ttaccaaaag
    23341 gaaggtaagt ccgttttgac cattgccatg ggatgtacgg gtggacaaca ccgtagtgtg
    23401 gcatttgcta aatgcttggc gcaggactta tccaagaatt ggtctgttaa tgaagggcat
    23461 cgcgacaaag accgcagaaa ggaaacggta aaccgttcat gagaaaacca aagataacgg
    23521 tgattggtgg agggactgga attcccgtca ttctaaaaag tctgcgggaa aaagatgtgg
    23581 aaatcgcagc tatcgtgacg gtggcagatg atggtggttc ttcaggtgaa ctccgaaaaa
    23641 atatgcaaca gttgacaccg ccaggtgatc ttcgtaatgt ccttgtggcc atgtcggata
    23701 tgcctaagtt ttatgagaag gtctttcagt atcggttctc tgaggatgcc ggagcctttg
    23761 ctggccatcc attgggaaat ctcatcattg ctggcttgtc agaaatgcag ggttcaacct
    23821 ataatgccat gcagttattg agcaaatttt tccatacaac agggaaaatt tatccttcca
    23881 gtgaccatcc tttgaccctt catgcagtct ttcaggatgg gacagaagtg gttggagaga
    23941 gtcatattgt agaccatcga ggcatagttg acaatgtcta tgtgactaat gctctaaacg
    24001 atgatacgcc tctggccagc cgtcgagtag tgcagaccat ccttgaaagt gacatgattg
    24061 tcctagggcc aggttccctc tttacctcta ttttgcccaa tatcgtgatt aaggaaattg
    24121 ggcgggctct tttggaaacc aaggcagaaa ttgcctatgt ctgcaatatc atgacccaac
    24181 gtggggagac ggaacacttt acagatagcg accacgtgga agtcttgcat cgtcaccttg
    24241 gtcgcccttt tatcgacact gtcttggtga atattgaaaa agtgcctcag gaatacatga
    24301 attccaaccg ttttgatgaa tacttagtgc aagtggaaca cgattttgta ggtctttgta
    24361 agcaagtttc gcgcgtgatt tcatctaact tccttcgtct ggaaaatggc ggtgccttcc
    24421 acgatggaga tttgattgtg gacgagttga tgcgcattat acaggtgaaa aaatgagttt
    24481 cacagtagca gtaaaagaag aaatcctggg ccaacaccat ctgagctggc atgaattatc
    24541 tgccattatc aaaatgtctg gtagcatcgg tctctcgact tcgggcttga ctttgtcagt
    24601 tgtgacagaa aatgccaaac tggcccgtca cctctatgag tcctttcttc atttctatga
    24661 aatcaaatct gaaattcgtc accaccaacg tagcaatctt cgcaagaatc gcgtctatac
    24721 cgtttttaca gatgaaaagg tgcaggattt gttaagtgat ttgcacttgg cagactcttt
    24781 ctttggcctg gaaacaggta ttgatgaggc gattttatcg gatgaggaag caggtcgtgc
    24841 ctatctctgt ggcgctttct tggcaaatgg gagcattcgt gaccctgagt caggcaagta
    24901 ccagttggaa atcagttctg tttatctgga ccacgcgcaa ggaattgcct cccttctcca
    24961 acagttttta ctggatgcca aggtgcttga gcgcaagaag ggggctgtga cctatctcca
    25021 gcgagcagaa gacattatgg acttcttgat agtaatcgga gccatgcagg cacgtgatga
    25081 ttttgagcgg gttaagattt tgcgagaaac ccgtaacgac ctcaatcggg ctaataatgc
    25141 cgagacagct aatatcgctc ggacagtttc tgccagcatg aagaccatta acaatatcag
    25201 taaaatcaaa gatatcatgg gcttagaaaa tttgccagta gatttgcagg aagtggcgca
    25261 actgaggatt cagcacccag actactctat ccagcagtta gcagatagtc tcagcacccc
    25321 tctgaccaaa agtggtgtca atcacagact cagaaaaatc aataagatag cggatgaatt
    25381 ataacgatat aaagcaaccc cttgaattat caatatcttc aaggggtttt gttgtgttat
    25441 gaaatcaaaa aggggcaatc aaggggcaga attaaaaaat agtatctaat ttattgacca
    25501 gtttatcctc catatcttca gtagtatgag aatagatttc caaagtcatt tttgcatttg
    25561 agtgcccaac tcgatccatt attgatttta ttgggaggcc agactctgct aaaaacgaaa
    25621 tatgagaatg cctaaaaata tggctagata agttttttct attttggcct gttttccata
    25681 tttttttaat atctgtatga agcaagctat tgttgtaggt tgattccatt tttcaaaaca
    25741 gaaaatataa tcatcgcttg acaatggctg gaaacgttcg ctaagtcgta ctatttgtct
    25801 ttgaatagct tctatgacac tctctgatac tttgattgtc cgtattgaat ttgtagtctt
    25861 tggtagcgtc ttgattttgt ttactgaatc aaaattacct gtgatctcaa ttttgttgtt
    25921 ttcgaagtct atattcttca gttgtaaggc agttaactca ccatatctca taccagttaa
    25981 tgtcagcaca agaaccatat cagcgtactt ttggtgatat tctcgacgat taaggacatc
    26041 gacaagtgct tttatttctt gcatggtgag aaagttgtta cgcttttttt ccagttcttc
    26101 taaagtcttt ggtttttgag gaatcgtagt ataatcgacc tcgttgtttt caatgtaaga
    26161 gtattgaaca gcgtaattaa agatacctct gagcctatgc cgtacttttt tagctgtaat
    26221 atatccgttg ctttcaataa ttttttcaat agcctcttga agaaaacgcc tgtcaagatt
    26281 agcaagtatg gtatcggatg gtatgacttc cttcatcttc ttatcaactg atttacaatt
    26341 atgttttgtt gattccttta ctgtttgcgc ccatgattta taaaaaaggt tatagatttc
    26401 ttcaaatgta atgctttcta cttgttttgt gctaagtttt ttatttatct tctcttgcaa
    26461 caagatagca gcttgatttc ttgcctgggg agttttcttc tccatggtta ctgaaacttt
    26521 ttttaatttc tcagtatatg gatctttgta tcgctcaaaa aatttatatt tgccgtttgg
    26581 taattcttcc atccacattg attttaacct cactttttga taaaatgggt atagtaaaaa
    26641 gggcttttta atgcctttta ctatactgga tatcctcaca ctcaaagttt ggcgatggcg
    26701 agtgtgagga ttttttgttt ttatagttat tctgatgaac tatcctatca attcataata
    26761 ttcgtcaatt accatcaatt cgtctgtgac tgttctaagc tcatgttttt gcatgaactg
    26821 gatatagttg aaagattgat ggtcgtctga tagtgcaagt tcttcttcta gcaacttatg
    26881 aatcatgtgc ctattagcct cattctcgca cctagtgtgg ttatttttat atagtgcagt
    26941 agaatgttcc agatgtccta attcgtggta tatgacccgt ttttttgcgt tttcggacag
    27001 ttcacggttt ataaagataa tactaatctc tttgatgtaa actccaggtc tttgccaaag
    27061 ttcattatca aagtaagcga gagtgacacc gtgtgagtct actagctctt caatagtcat
    27121 aggctatcat cctttttgtg ttattttgtt gttaaaatgg ttacgatgat tgctagtatc
    27181 cccagtaaag tactaactaa cagtccgata aaccaataca tgaactcttt tttgctttta
    27241 gcttgctctt ctaatctctt attctcttga gttagaaaca tagtctctac acgtttctcg
    27301 aaattatcaa attttaaatc aacttgttca aattttaagt cgattttttc aaatccgcta
    27361 cgcatttctt gtctgagttg atcaactttt aaatcaattt tctcgaatcc atgctgagtg
    27421 tcagaattaa ttttatcaag ttttaagtcg atttcagatt tgctgtaagt atcttgtgac
    27481 ataatatttt cctccgataa catttctgac tccattatat catgattttg tatgggtaca
    27541 gttttcgatg aagatttaga agcgtaaagt gaagaaactt tggaaggggt aggtttgaaa
    27601 ttatcttgtg tgtccggcat tgtttacccc cactttccaa aatgatgata actatatgct
    27661 gtatctactt cctgaccgtt ttcgtccatc aagacgaaga aaaagtaaaa atcgctcggc
    27721 ttttctatcg taaaattaaa gctaaaattt ccagtggcca taccaaagcc gtcttcaagt
    27781 agcacaaatt cttgtctcgc aatatttatt ctcgtagcat ggacagggta agacgtgcca
    27841 ttagggaagt gggcagttag agacaagata taatctgttt caggtcttag attaaagaag
    27901 tctagaaatg caaccaaaga tgtcgaacca ggaaacatat cgaaattggt tattgttcct
    27961 agcaattgag ctgtttcagg attgacaata ctgattgctg tcatcttttc tctgaacgga
    28021 ttcttcttca ttggaatgtt cgtcatacta tctacctctc aaataaatct caataatgtt
    28081 ctgaatggca tcgatgtctt cttctgtaag tggcttgcca tcgaaggtct tggcattctc
    28141 tgccatcttt cggaggtcgt cagacgtgta tcctgcgatt gtatcatcac cagcaatagc
    28201 aggattatct gtgcgaccaa gtaagtagtc tgtagataca ttgaagtagt cagcgatttt
    28261 ggatatatgt tcagcagatg gagtcttttt atttttaaga ctgtaaatgt aatttttccc
    28321 caaaccaacc ctatcttcta aagtgtttag agaaattccc tgttttttag ctaaactttt
    28381 aattttttcg aatgtctcaa acattgatac atcaaccttt ctgaagcatt acaaaaaaat
    28441 attttatttt ttcgcctaaa acacttgaca aaaattagac gaacaactaa aatagtattt
    28501 gtaagtaatt aacaactaaa aaaacaacta agaaataaat tataaaaatg tttttgcgaa
    28561 cggtatttat agatttatta gtgtttttat tatgctttca ttttacacga acatctaaaa
    28621 aaagtcaagc gaaaagataa aaaatagtta catttttagt tgtttcttat ttacaaaata
    28681 agtaaaaagg aggaacgtgt cgatggtaag tattcttaaa aatttagaac aagaaaaaga
    28741 ccaccttgaa aaaatcatta aggtagtcag cgctggtggt aaatttctga gattgccata
    28801 tcaaaaaaag tcacgctcga ttagtgagaa tctgaaattg atttctcaaa atcttgataa
    28861 attgagcgag caagttcaac aaaccacgaa tcagcattca tgatttcaag atgacgaaag
    28921 aaacctgttt tggtttccag ttcagaatcg tgtgcataac gtaatatttc tctagcaaag
    28981 atggtttcaa aatcaaaatc tttaccatcg tcgtagatgt cgcgtttgct tgctttgagt
    29041 aaatattctt taaaagtcat aaggttaact cctttctgct tatattatag cagaaaaaga
    29101 agaaagaaaa agaaaggaga aaatatgcca gatatcgcaa acggtcgcga aagagttatt
    29161 gctttcttga aagagaaagg cattaaaaaa gcaactctag cggttgctta cggctttaaa
    29221 cgacaggaag tgacaaacat tctaagtgga acgactaaag gtccacgagc gaacagtttc
    29281 attcttcagg ttattgaaga ttatgggatt gagtaggaaa gatttgagga gtaggaaaat
    29341 gagaccaaga cgatatccgt atagtgggaa aaaagagtcc acctttgtga aggcagaccc
    29401 tgaattggta gaaaagattc taagaaacat cagttttctt gagcatttac aagttgtgtt
    29461 agcaacgaaa ctgtagtttc tgtgctgagt ttatgagcga caagaacgct atagaaaata
    29521 gcttctctaa tctctatgtc gattggatat ttttcaaata cttcatccaa catatctttg
    29581 ataaccggaa tagcatcgtt gataatgtct tgagaaactt gtaaaacatc ttctttagtt
    29641 aatttagaca tatagttttc ctcctttctg atggaatttt gactaaaacg gtgagaggtc
    29701 ctagtcaaaa ttattatagc aatttaggag gaaattacat cagtcttgag gctgatatag
    29761 gaggttgaat ggaagataaa atcattgaac ttgctgatta cttcatcagc gaatctacaa
    29821 cgtacagaga agcaaaaata gcgtgtgaga agctattgaa acaagtcagc catgagatag
    29881 aactcagggc gatggaaagt aggacagtct agaagacaac aaaaagcacc tgacggcaat
    29941 caggcgcatg acaaaattat tcaaaacacg aaaggagcaa aaatggaagc agttgaaatt
    30001 gtaagaatta aagatgtgat tattgaaaaa gtctctgcta atgatgaaga gttaaaacgt
    30061 atctttggat gttcaaaacg acaagcagga gagcgaagaa gagaaatgca aaaactccct
    30121 agtcagcaaa aacatctttt ggatagtgga caacttgtaa cgattaaagg tttctatgaa
    30181 tacttgcaat atcgtggaac taaagcttgg aaaaaagaaa tggaaacaag caagaaaatg
    30241 aggtcagcag gatgaaccta ctatcaagaa tcaaaaacta tttttcggaa gaggtcaaag
    30301 aaactaatct cgactggaaa gaggtcgctt tagacctcaa tcaatcacta attgaaacac
    30361 aggaaaaact tcaagaagcg aatcaagaaa tcgcagactt gaagaaaatc gtagcaatct
    30421 acaaagaaaa ggagaaagaa aaatgatgga atacatttac ctggtaataa tcgtaggaat
    30481 tggactatgg tcgctagtaa ataaactaga tgaccacgct gaaatgaaac aaaaagagcg
    30541 ccagctgatg gcaaacaatg tcgcacggat gaatctgaga aattcagata agcaatttac
    30601 ttatgatgta gaaccgcctg aagggttgaa ataaggagga gaaacatgac tcaagcggaa
    30661 caaattaggg aatattatag agagcaccct gctgcctcat gtgatgaagt ggctgaggtt
    30721 gtcggtacaa caaaaagcaa cgtaagtgca aacctggcca aagacatcaa ggcaggcaga
    30781 tgcgttcgct tggaagataa gtcatacgac tactcgcctt actataacca tacacaggca
    30841 ctcactgagt tggttgattg gaagaatgat actagacgtg agtgggtgga tatgctgaca
    30901 agagcagcag aaaaagaaac ggttagcaat gttatgcgtt tgttaatcaa agaagcaaat
    30961 aaattgatga aagaggtgac gaagtagatg gttcgaaata aattgacaga tttaaccaat
    31021 actcttttcg cccagttgga aacattggac gatagggatc ttactgcaga tgaattaaag
    31081 acggaactcc aacgttcaaa acagatggtc gcaatctcag gtcaaatctt acaagcaggt
    31141 caattggcgc tagatgctga aaaattcaaa gacaaggtag gtgaagtcaa tgccccgatc
    31201 gctttgctgg aaggatgagt atacagagta catgcatgag atatgccctg gccgattaac
    31261 tcctgaagta accaggttac taaatgagaa atttggtacg acctatacca agactcaaat
    31321 aggagaagta cgcagacgtt tagggttacc tgttggaaaa gtctatcaag gtaaattgtt
    31381 gacaaaagaa caacatgatt accttgtgtc aatccaaaaa aataagattt ctcgcgatgt
    31441 cgcaaatgaa atgaacctaa aatttggatt atcactgact gagaaacaga ttaagagtta
    31501 tcgaagaaat aataatctac atagtggttt gacaggaaga ttcgagaaag gtcagactcc
    31561 tcacaataag gggaagaagt accccaatat gccaaaaaac agcgggcagt tcaaaaaagg
    31621 taatcgacct ctgaattatg tacctgtcgg tactatcaac tacacaacag acggttatcc
    31681 aaaagaaaag attggagaac ctaatcaatg ggttttgaaa caccgcaagg tttgggagga
    31741 acatcacggg ccaataccaa aagggcattc gattgtcttc ttggacggtg ataaaacaaa
    31801 ctatgatatt tcaaacctgg catgtttatc taaaaacgaa attgctagaa tgaatcaaaa
    31861 tcatttattt acgtccaacg ctgatttaac caaatcaggt attggactaa caaaactcac
    31921 aaacaaaatc agagaggtag aaaaaaatgg ctagtttata cgaactgaca ggtcagtttc
    31981 tgacagttta tcaaatggat attgatgacg aaacaaaaac ggacacactt gaggctatcg
    32041 attggcaaga acaattcgaa cagaaagcag aaggatatgc ccatgttatc aagaatctag
    32101 aagccgacgt ggccatgtac aaggctgagg aagagagctt caaagccaag aaacaggtgg
    32161 cacagaaaaa gctggattat gtaaaggata acattatggc agctatgaat gtcacggggc
    32221 aaaccgaagt taagagtggt gccctgatta taaaaattgc taagaatcca gaatcagtca
    32281 aggtcaacga agacgacctt ccgaaaaaat attttacaaa aaaagtgacg cttgcgccgg
    32341 acaaaaaaac actcaaagag ttgcttaaat ctggcaagaa agtcaaaggt gcggaacttg
    32401 tccggacaga aaagttggtg attaagtaat ggaattgatg aataaaacac gagtaacaga
    32461 ttcactagca gttgtgattg gaccagaatc gattgaagta cttgttactg aaggttttct
    32521 atttgatgtt gcgattcgtt ttgtaaaagt agacgaaaca aatcttgatc aaggaaatga
    32581 aaagccagta ttcactccgg aatacaagct ggtcacagtt gctaaataca aggaaaaacc
    32641 tatctttgaa tcggaggaag atattcgaaa atttgagaag caagcaaaag aagttaaatc
    32701 gctatttgcc tttgcaaagg taaataaaca aaattggttt aacactgccc tttatccagg
    32761 agtgctgact gagaaagttg gtgtttgatg aaaattttag ctattgatcc aagcagtaat
    32821 aaaattgaaa ccagcacaac aggagttgtc ttgttggata atgcaagatt agttgatagc
    32881 tgggttgtct cttatggtat gagaggtttc gctgattggt ttcacgaaat cggaacaaat
    32941 cttgaattcg atgtagttat tgttgaagaa tttaaggcga gggataacga caagtcgaaa
    33001 gataatagcg tggcagaaac catcgcctat atccaacttt gctatccagg tgccattctt
    33061 caattcaatg caggttacaa gtcggatatt ccaaacgatc ttttgaaaat cttagacctt
    33121 tggaaatttg aaaaaagtca tcatcaagat attcgagcag cagcaagact tggattattt
    33181 tgggcaatga gaaatgatat tgaagaagtg gttcatgata tcggaaaggt ggtgagtgag
    33241 tatcacaata acgctaagaa agtggcaagc tgaagcgatt aaaagaagtg aacatttatc
    33301 taatggaatc tttttagagg ctcttggggg cagaggcaaa actatctgtg cacttgctat
    33361 tgcaaaacat aaaaaagcta aaaaaatcat catcacaaac aatcgactag ctattctgaa
    33421 tggttggata gatgcagtca agtttatgaa ttttgataaa ggtgttgaga ttatcattca
    33481 gacagataga tatcttcaaa atcaagtcaa aaaggggcat aaattagatt gtgatgtgct
    33541 gatagtagac gaatggcaga atatgtcttc tgacaaacaa gtggccttat atcgcaaaat
    33601 aaagcgaaaa tacacgatag gtctttcagc gacaccaatt cggaaaaaag gacaaaattt
    33661 ctatccactt gaaaaaacgg tatttggttg ggcaacccca aataataaat ttgactggca
    33721 aaagactcat ggaaaaatgg tctatgatcc atttagctat tcaaaagaga agtgggaaga
    33781 ttttcaaaat tatgaaagtt atatctcgag cttgcctaat ttcttccgct gggaagagat
    33841 tgaaggaatt gagaatgcag ttgagaataa cggttttgag attaagtttt accaaaagag
    33901 agtcgcctct ggcaatccag aaaaacttgc agaatttaga aaactaaatc ttgtaacagt
    33961 ggacggcaaa actgcaatgg ccaagcaatc gtttggaaga aagacctttg aacgctacct
    34021 taatcaaaca ggcgtagcag tcgattttcc aaaattaaag ccagtaaatg cggatacgcc
    34081 attgatgtta caacttgacg gtttaatcga acgagcacca cacgatatgt tgattgtcag
    34141 taaatctaag cagattgtca acgtcattag cgagcgccat cctgaaattg gaatctggac
    34201 gggcgatatt caagaaggac tttataagaa attcgtggtt gctactagtc aagtgttagg
    34261 tgtcggagta gacggcttgc aacacaaata ccaaactatt gtcgtattgg atccagtaga
    34321 agaaggttct ggagaatatg atgattatcg acaattgctc tggcgtataa caggaagtcg
    34381 tcagcagcat gatgtaaatg taattgaatt ttattataaa gaaagttaaa aaaaagagga
    34441 aaacaaaatg aataaaacaa ctgaaatgat cgtatttcgt agccgtaaaa ctggagaatt
    34501 tcttaattct tacaaggaca gaagttcttt agcatttgca gctgactttt gcagcttgga
    34561 atattgtttg aagcttcctc gtaaaaaata cgaagacaac aaaaagactt acaaggctct
    34621 tgctgcagct tttgactgtg aaattgtcgc agttgaagcg gaatacaaat tgacctatcc
    34681 gaatggatca gaagttgaac ctatcaagcg tgaccgttca tcaattgagg acatgattaa
    34741 ggatattatt ggaggggttc tctaatggca tttacacttc cagcaaataa accacaagtt
    34801 cctaaagata ccccacgaaa ttttttcatc tacggtgaaa ccatgagcgg aaagtcttat
    34861 cttgcaaatg aattcccaaa tccaatcgtt ttgaacacag acgggaatgc agaagctaac
    34921 actgttccaa gcattcagct gatcaatgaa aaagatgaca agggacgaat taccaattca
    34981 gtaattaagc agcttggaga tatcttgctt gctctccaga cacagaagca ctcttatgaa
    35041 acagtcgtta ttgatgtaat tgacgatgtt attgaaatga ttaagattgc agtttgtgat
    35101 gaattaaccc cagttggtaa acctcgcttg aaatccttgt cggaaattcc atacggcaaa
    35161 ggatacgact tctttaacca agctatcaca gaattagtca ttgacctcaa agcattgcca
    35221 atgaatgtta tttacatcag ccgtcaggta tctgaatatg atgacaatgg caatgccacc
    35281 aaagacaagc caagcttgaa agataagtat gtcaatctta tcaatggaaa ctctgatttg
    35341 atgatccaca ctgaaaaact cggcaacaac tacaaccgtg aggttgaccg caagcgtaag
    35401 acctattatg cggaccaggt tgatgacaag gccatcttga aaatcttggc aactatccgt
    35461 ggggctgttg agcctgcaaa gggcaagcta gcccctaaaa aagaagcagc taagacaact
    35521 aaaccagcta agaccgaaaa aacaaaagag gcacctaaga aagaagttga ctctgatgat
    35581 gaactatttt aagaaataaa ggagaataca catgagctta ctagatatcg caaaatcaat
    35641 caaaaaagag ggctttgacc cacgcaaaga cagcgccaac ggtcctgcac caatcccagc
    35701 tggtacttat ccagtagtcc tgaagaaagc aaccttcaac gtatcggaca aaggctggga
    35761 aagtcttggt tatcaatttg aaatccgtgg cggtgattac agtggacgct ctgaatttgc
    35821 aacatttggc acactgactg aatggaacgg taagaacctt gactgggcag ttgaacgcac
    35881 tatgaaattc tttatcaaag ccttggttct tgctggcgac agtatgcaag gaaatgaaga
    35941 agacggtaaa gccttggaag aggctctaaa acgtaaggca gttggctctt actacaacct
    36001 tgttatctct gtgactaagg ggaaagatgg ccgtgagttc cgaaactatg accttgaaga
    36061 agaagaagca caaccgctga ctgaagctga tattgatgac gatgacctcc ctttttaaga
    36121 aataacaagt tctgggtcat tgatgaaact gatgaggaat ttggtccttt cacgacagta
    36181 gaagaggctt atacagctat gctaacatac ttggatatga ctgaagccga atatcagtca
    36241 aactatacgg cccaggaact tgtttatatt tacaaagagg agaaaaaacc atgccgtcga
    36301 tgaaagaata cgcattacag taccaaaagt tagggttctc agtcattcca atcaatccta
    36361 aaaacaagat gcctttgatt gattttgctg ataagccagc catgactcca tctgagattg
    36421 aaaacttttg ggacggctac cctaatgcaa acattgccct aaagactacc aacttctttg
    36481 tcattgatat tgacaaacac ggcaaatcga acggttttga atcgctaaaa aaatggaaac
    36541 atctaaattt aatcgaaccg acactgcaag ctaagacggc tagtggcggt aaacatctat
    36601 tctacttcaa acgagaagat gagccgatca ctcagatgat tggattcttg cctggtgttg
    36661 atattaaggc tcacgaaaat aattatgtgt tagtcgcacc ctctgccaca gataaagggc
    36721 agtatgagtg agatctggaa aagtctaagg aaggtggcac gatggtcact ccttcaaaag
    36781 atttaatcca gtctataaaa aaacagtatg gcgaaactca cggttataag tatgatggta
    36841 aggacggtct tagggattta gttagacgtt cacatactag agaccgaaca cagactacag
    36901 atctctttga aaccatcgcc cttggttttg gtgatgaagg tggacgaaat gacaaactag
    36961 caaaattcgt aggtggtctc ttatatcgtg cggtcgacga tggtgtagtt gttcaacttg
    37021 caagattagc aaatgcaaat agtccaaacc ctttgcctga aaaggaaatg atgcgtacta
    37081 ttgaaagtat gattaaaaaa gataggaggt gattgtgatt ggtaatgtag taagtattga
    37141 ctcacaacct aagatgataa cgactgccaa gggagacatc aaggccaaca gtccaagtaa
    37201 tgtgttgatg tctttcaaag ctgatgatca gttgagtatt tacctaaagc acaacgattt
    37261 ttcccaagag catgaactcc ttaaagatat caagatcggc aacactcttt ttaaaaaagg
    37321 tgagctccct tctaactttg attcagtcgt aaaagtttac tttgaaagtg tgttaggtgt
    37381 tgctttctca aaccaagcga tgcttgatgg catggagact ttcttttcag aaagatcata
    37441 caatccagtt attgagtata tggagagagc agctgaaaag tgggacggca gaaaccggat
    37501 tgaccgcatg cttcaagtat atctcggcgc tgaagatatc cctttagttt ctaaaatcgc
    37561 tcaaatgtgg ctagttggtg cagttgctaa agtttatgat ccatacgtta agtttgacta
    37621 tgttctggat ctagtcggtg gacaaggagt tgggaaaaca tccctccttc aaaaattggg
    37681 tggcgaatgg tatacggatg ccgtaacaga tttctctaat aaagacaatt acgacattat
    37741 gttaaagagt ctaatcgtca acgacgacga aatggtggcc agtaatcgga tgagctttgc
    37801 agaaactaag gcctttattt ctaaaactag cctacgttat cgtaaaccat acatgaaacg
    37861 cacagaagag tttgccaaaa acttcatttt agctagaact actaaccaaa cagaatacct
    37921 caaggacaaa accggtgaac gtcgttttct accagttatg gcagatagta aacggcaaaa
    37981 aaaacatcca atggaaatcg agccagagac aattgaacaa atctggggcg aagccgttac
    38041 aatctatcgt gctggtgctg atttgatgtt tgatgaaaat acagaggatg aactgaatat
    38101 ctaccgtgaa cagttcatgt atcgtgatga agttgaatta caagtgcttg aatatcttga
    38161 tatgcccgtc cctgaaaatt ggcaaaactg gtctattcag caacaacatc aatacacaag
    38221 taaatatttc gataatagta gcgactttga tcctggaagc aaaaaactag ataaggtctc
    38281 aactcgtgaa atgatgtaca acttatttat gagaaattcg aatgacagga agctgtcaac
    38341 gaagattaac atgatcatgg ataatcatcc tgattggaaa aaaagtgttt tccgggcagg
    38401 aggtaaaagt acaaaagggt tcgtaagagt gaaagattcg gaaaaaacta atcggtagca
    38461 attaaaaaat tatcggtagt catcggtagc agttgagggg gtagatcggt agcattctac
    38521 cgataaaatg agacatcggt agcatatcgg tagcagtcta accccttgat attactgact
    38581 tttatttaat atttatatat aatgctactc ttctacctat atttttaaaa aaagtatata
    38641 aaataatagt aataatagag aaagcctata aaatagggat tctttaaaaa tattttttac
    38701 tttttagaat ttatcggtag tacggtagca gtttgaaaaa aagaggtaaa aatgtcatac
    38761 acagtaacac tatattttga caacatggta gacgaaactc acctttttaa gaaaaagggt
    38821 gatgctgcaa aatgcaaggc tcagctcgag agcaagtatc gaggtgatcg aatgtataaa
    38881 gtaaagatgg aggagatgga gtaatgagtt atgatttgga aatcttagcg aaaatagaga
    38941 gtggagatta tatttgtatt gctgaaccta gatatagttc tccgacctac aatcttggaa
    39001 aaatgtttag ggtggctatg gattgggatt tcgaccaagg cacaatttac aatgttgctg
    39061 atatttttga aaatattaaa cgtggcataa ctgaattgga aaggcaacct gaaaaatatg
    39121 tacaatatga acctgcaaat aaatggggaa cgatcaatga tgcgttatat gttttgagat
    39181 cgttaaggga ctgtatttta gaacaagata ttgatacgaa atatttatat gtgaggtggt
    39241 aaattgaaac gaccaaacag atacccgtac actaaaaatc aatgggttga agaaaccttt
    39301 gatcactata cttataaaaa cgatatttgc tatacaagtc acattttaga aaatagactt
    39361 actggagaaa ttaaggacaa ggagttgaag tgatggaaga gttaaagaaa aaagttaatg
    39421 cagtatacaa ctggacggta gaagacggga agccgcaacc tcccaagcaa gatttaccac
    39481 aagcggtgaa agaccgggcg gactattttt gggaaatggc agaagatggt atgacgttta
    39541 tgggagcgat ggaatgcatc tttgctgatg aaaagcctac agactatgat ttgggagcta
    39601 ctaagggttg gttgccaaaa tctaaggagt ttgatgattg gattggctat tcgccaagca
    39661 tggctcaggt agttattgca gtttatttga tttatggagg aaactaagat gaataagcag
    39721 gaattgatta aaaaattaga ggaacgaaga acaataactg ggaattttca aggttatgta
    39781 gtttggtgga aggatgtaaa agaaatcttt gaacaactag gcgaaccgca accagtcaaa
    39841 gtaccgcagt gtgtggcgga atatatagaa tttaaaaaga aaaacaattt tcatgtttac
    39901 ggtgcaatga gagtaattga agatcattat gataagaaag ttcctgattg gttttacgaa
    39961 aataacatcg aaaaattctg tcttgcttgg cttaacggct acgaggtcga aaaagagaag
    40021 cggtattttg ttaagattaa agggaatatt aaagaaaata tgttggttta tggagaattt
    40081 ttgaaaaggt atttctttac aaaaagcttt agtttagatg atgttatata ttcccacact
    40141 cgtaaagaac tagaagacgc aaacttcggc tgggtgtttg attgttcagg gattgagatt
    40201 gaggaggtgg agtgatgagc cttacgctaa atagcacaat tggagactta gttttggcaa
    40261 tcggagaaat tatcgttggt tctgatggta aaaccactac agcgatactg gagatacctg
    40321 atcaaagctt ttacttagag attgcgctta aattgaagga ggaggtcata aattgaaacg
    40381 attcatagct atctggattc tgctatctgc tggattgaat atctggcaga tggataggat
    40441 tcgagatttg gaagagaaga agccgatggt tatctacaag gctgataacg taggtgctga
    40501 gatatgagga ggatttggca tgataccgaa atttagagtg tggcattatg aattaggtag
    40561 actgatgtca gtcaaatgta tgttttttca ggatagcgag attgaagaat ttgagttaaa
    40621 cgatgcttta atgaatgatt acattacagc ttatcctgac gaaatcgaac tcatgcaatc
    40681 aacaggactc aaagacaaga acggcaagga ggtattcatc ggtgacatcg ttaaatgtac
    40741 aagaggatgt ctccatgaag tatatttaga aaaagaatac ggtggcacat tcataggcgg
    40801 aatgccttcc atatatctaa agggattgct aaatgggtat gcgtggactg aagacgagga
    40861 aatcatcgac aatgtctacg aaaaccctga acttttggag gtaactcatg aataaacgtc
    40921 aacgcaaaaa gaaaattttg aacggtctga acaaagaaga aagataccac aggacgcatt
    40981 gtcctgtctg cgatagcgaa gctggtttat tcgacagata ttttaatacg tacggtttct
    41041 gctctgaata ttgtggttat gaatactatg gaatttcaag attataaaat aaaggattga
    41101 ggttaaaatg acattatttg atgaagtgca gcaattaagc tcagaaagcc acgcaaaatg
    41161 gttcgagcga tattttgaga aatataacct agaacaaaaa ctaaaaactt ctgctcaaaa
    41221 aggttataca ggttatttaa tcaatgtttg gtcagttaga gacgaatatc tcaggaatcg
    41281 attaggagat gaaataacgt ttgaagcgtt aagagaatta ttaggagctg gctttactgt
    41341 caaatataag ctttatctat ctaaaaatat tttcactgga caagatttcg tttctaacaa
    41401 gaaaattcac attacttggt aaaacaaaaa agccaagaca ctctctgtct cagcaataat
    41461 ctcaataata ttattatatc acaaaggaga cagagagtga acaaggctaa agaactattg
    41521 aaagagttgc agaatctgga catggacatt caaagccgta tagatgaaat taacgagctt
    41581 gaggcaggtt tgctctcaag tcctaagtgg tcagatgtca aagttcaagg tggtcaagct
    41641 agaaaagttg atgatgtcta tactcagctt gtcgtgatga aagaggctat agaacaggat
    41701 actaaagagg ttatcaacag aaagctccaa ctaggtagga tgatcaatag gcttaaaaat
    41761 ccaaaacata gaactatttt gagaatgact tacatcaata agatgtacgt tgatgacatc
    41821 tgtgacagca tgaggggcat aagttctcct acttactatc gtttgaagaa acaggcagta
    41881 aaggagcttg atattattct ttcagaattg atagtaaatg atagtaactg tacaggcatg
    41941 aagtctaaaa tctgttaaaa tggtagtatc aagaattgaa aagagaggtc tcagaattgg
    42001 tagatggtta cctgtaatgt cagggggctg taatggcctt ggaggttcaa atcctcccct
    42061 ctcctttgag tgtttgtgtc ctagaatggg gtaggcagta ggcttagcat tcatatatca
    42121 ctcattaact taaaaatggt tgcggaagcg actggacctc gcatgattgc gtagctaatt
    42181 atattccgga taagttataa gctagagggt ttgattccct cagaggtttt aaagactaca
    42241 aaaaataaaa aagaagtcaa aatttaatac gcacgcaagg ttgtagtcgc cttgcaagaa
    42301 ggtcgcacat cgtgtggctt tttttgatta ttcgaagggt ggtgatggaa aattgagtgg
    42361 attgagaata aaacaaaaga gatttgcaga tgagtacatc atctcaggta atgcgacgga
    42421 agcctataag aaagcaggtt atcgtgtttc tagtgataga gtggcaggcg ttgaaggaca
    42481 taagttacta aagaatccta agattaaaag ttatatagat gaacggttga aacagcttga
    42541 ttctgaaaaa atcgcagacc agcaagaagt ccttagttat ctaacctcgg taatgcgagg
    42601 agagacgcaa gagcagactt tgataagcat cggagaattg ggtcaaacga ttacggatat
    42661 tgatgttgga gcaaaagaca gaatcaaggc agccgaacta ttaggaaaac gtcataggct
    42721 ttggacagac aaagtagagg caga
//
LOCUS       DAVKZI010000015        42119 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKZI010000015 DAVKZI010000000
VERSION     DAVKZI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.015"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(111..1535)
                     /locus_tag="VXB18_000934"
     CDS             complement(111..1535)
                     /locus_tag="VXB18_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382154.1"
                     /translation="MPVYFSFVVAILLVIAFSTSLTAFYNVFYESKDLASYRPYAFKE
                     SEIIIAKGLSVLFPALTGIVPILAYFLALYISLAPSLWLGLPLMLLSLTLLFVSVALV
                     MVVAVHFLAQTTAFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGSIVDKVRDIPFLL
                     YPLHIFYKIAVEPFSIEAILGLLAWIALTVFLLYLTKKKVLPRFYDVILLNSEEKVKK
                     ERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYLMMISLISKIRDS
                     QIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERKNVDFLKSLPFDFARYVK
                     VKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIFSCHHYFKDVKNL
                     STNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSPILAINLGVGALI
                     VLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1726..2475)
                     /locus_tag="VXB18_000935"
     CDS             complement(1726..2475)
                     /locus_tag="VXB18_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382155.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQDLSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2654..4108
                     /locus_tag="VXB18_000936"
     CDS             2654..4108
                     /locus_tag="VXB18_000936"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0382156.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4198..6816)
                     /gene="alaS"
                     /locus_tag="VXB18_000937"
     CDS             complement(4198..6816)
                     /gene="alaS"
                     /locus_tag="VXB18_000937"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0382157.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(6838..7323)
                     /locus_tag="VXB18_000938"
     CDS             complement(6838..7323)
                     /locus_tag="VXB18_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0382158.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7598..7837)
                     /locus_tag="VXB18_000939"
     CDS             complement(7598..7837)
                     /locus_tag="VXB18_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382159.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8090..9160)
                     /locus_tag="VXB18_000940"
     CDS             complement(8090..9160)
                     /locus_tag="VXB18_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0382160.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9157..9930)
                     /locus_tag="VXB18_000941"
     CDS             complement(9157..9930)
                     /locus_tag="VXB18_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382161.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9927..10733)
                     /locus_tag="VXB18_000942"
     CDS             complement(9927..10733)
                     /locus_tag="VXB18_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382162.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10714..11871)
                     /locus_tag="VXB18_000943"
     CDS             complement(10714..11871)
                     /locus_tag="VXB18_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382163.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12032..12937)
                     /gene="murB"
                     /locus_tag="VXB18_000944"
     CDS             complement(12032..12937)
                     /gene="murB"
                     /locus_tag="VXB18_000944"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0382164.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13049..13801)
                     /locus_tag="VXB18_000945"
     CDS             complement(13049..13801)
                     /locus_tag="VXB18_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0382165.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSTVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13811..14542)
                     /gene="budA"
                     /locus_tag="VXB18_000946"
     CDS             complement(13811..14542)
                     /gene="budA"
                     /locus_tag="VXB18_000946"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0382166.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGTGEQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14684..15955
                     /locus_tag="VXB18_000947"
     CDS             14684..15955
                     /locus_tag="VXB18_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0382167.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15975..16801)
                     /locus_tag="VXB18_000948"
                     /pseudo
     CDS             complement(15975..16801)
                     /locus_tag="VXB18_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(16958..17611)
                     /gene="phoU"
                     /locus_tag="VXB18_000949"
     CDS             complement(16958..17611)
                     /gene="phoU"
                     /locus_tag="VXB18_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0382168.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17623..18381)
                     /gene="pstB"
                     /locus_tag="VXB18_000950"
     CDS             complement(17623..18381)
                     /gene="pstB"
                     /locus_tag="VXB18_000950"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0382169.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18394..19197)
                     /gene="pstB"
                     /locus_tag="VXB18_000951"
     CDS             complement(18394..19197)
                     /gene="pstB"
                     /locus_tag="VXB18_000951"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0382170.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19208..20092)
                     /gene="pstA"
                     /locus_tag="VXB18_000952"
     CDS             complement(19208..20092)
                     /gene="pstA"
                     /locus_tag="VXB18_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0382171.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20082..20999)
                     /gene="pstC"
                     /locus_tag="VXB18_000953"
     CDS             complement(20082..20999)
                     /gene="pstC"
                     /locus_tag="VXB18_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0382172.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(20999..21877)
                     /gene="pstS"
                     /locus_tag="VXB18_000954"
     CDS             complement(20999..21877)
                     /gene="pstS"
                     /locus_tag="VXB18_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0382173.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22451..23755)
                     /locus_tag="VXB18_000955"
     CDS             complement(22451..23755)
                     /locus_tag="VXB18_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0382174.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23756..24529)
                     /locus_tag="VXB18_000956"
     CDS             complement(23756..24529)
                     /locus_tag="VXB18_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0382175.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRSLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24519..24797)
                     /locus_tag="VXB18_000957"
     CDS             complement(24519..24797)
                     /locus_tag="VXB18_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0382176.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24797..25198)
                     /locus_tag="VXB18_000958"
     CDS             complement(24797..25198)
                     /locus_tag="VXB18_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0382177.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25410..26027)
                     /locus_tag="VXB18_000959"
     CDS             complement(25410..26027)
                     /locus_tag="VXB18_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0382178.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(26017..26790)
                     /locus_tag="VXB18_000960"
     CDS             complement(26017..26790)
                     /locus_tag="VXB18_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0382179.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26801..27538)
                     /locus_tag="VXB18_000961"
     CDS             complement(26801..27538)
                     /locus_tag="VXB18_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0382180.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVFRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(27543..28673)
                     /locus_tag="VXB18_000962"
     CDS             complement(27543..28673)
                     /locus_tag="VXB18_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0382181.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28757..29146)
                     /locus_tag="VXB18_000963"
     CDS             complement(28757..29146)
                     /locus_tag="VXB18_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0382182.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29162..29545)
                     /locus_tag="VXB18_000964"
     CDS             complement(29162..29545)
                     /locus_tag="VXB18_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0382183.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29546..30334)
                     /locus_tag="VXB18_000965"
     CDS             complement(29546..30334)
                     /locus_tag="VXB18_000965"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0382184.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYHQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30327..31262)
                     /locus_tag="VXB18_000966"
     CDS             complement(30327..31262)
                     /locus_tag="VXB18_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0382185.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31392..31568)
                     /locus_tag="VXB18_000967"
     CDS             complement(31392..31568)
                     /locus_tag="VXB18_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0382186.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31708..32415)
                     /locus_tag="VXB18_000968"
     CDS             complement(31708..32415)
                     /locus_tag="VXB18_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0382187.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32566..33594
                     /gene="queA"
                     /locus_tag="VXB18_000969"
     CDS             32566..33594
                     /gene="queA"
                     /locus_tag="VXB18_000969"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0382188.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34255..35382)
                     /locus_tag="VXB18_000970"
     CDS             complement(34255..35382)
                     /locus_tag="VXB18_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0382189.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKYRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEKVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVIVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(36097..36648)
                     /locus_tag="VXB18_000971"
     CDS             complement(36097..36648)
                     /locus_tag="VXB18_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382190.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(36998..37822)
                     /gene="nadE"
                     /locus_tag="VXB18_000972"
     CDS             complement(36998..37822)
                     /gene="nadE"
                     /locus_tag="VXB18_000972"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0382191.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAIEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(37819..39279)
                     /locus_tag="VXB18_000973"
     CDS             complement(37819..39279)
                     /locus_tag="VXB18_000973"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0382192.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(39395..39883)
                     /locus_tag="VXB18_000974"
     CDS             complement(39395..39883)
                     /locus_tag="VXB18_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382193.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(39873..40082)
                     /locus_tag="VXB18_000975"
     CDS             complement(39873..40082)
                     /locus_tag="VXB18_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382194.1"
                     /translation="MAKNLKLKLARVELDLTQGQLADAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(40468..41196)
                     /locus_tag="VXB18_000976"
     CDS             complement(40468..41196)
                     /locus_tag="VXB18_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382195.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISASIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(41212..42090)
                     /locus_tag="VXB18_000977"
     CDS             complement(41212..42090)
                     /locus_tag="VXB18_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382196.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDF
                     ETKKETLKDIYLNRSK"
BASE COUNT        12635 a         9495 c         7830 g        12159 t
ORIGIN      
        1 acattcctcc ctatattttt gattaccaat cttaatcatt tacaactaca ttctaacaaa
       61 ctataaaagc gtttgtcgaa ttgaatttat caagcaagca accaactatc tcatcttttt
      121 tctatttctg ccaatatgcg tgacaggtaa taatgatagc caaaaatagc aagagcaagc
      181 aagacgataa gagctcctac tcccaagttg atggcaagga taggggagag agactgaacc
      241 aagaatatgc tcccaattac aagggccatc aggattgcac tataaataaa caataaaact
      301 atggcgacta tgccatttga acgattcacc aggtccgtaa tgctactcca attggttgac
      361 agatttttaa cgtccttaaa gtaatggtgg caagaaaaga tgacactggc aatgatccag
      421 actacaagaa ggtaaatcat cgaaaggatg gacaagccta gatatagaga aagaccgagc
      481 aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa tccaaaattt cactttcaca
      541 taacgagcaa agtcaaaggg taaactcttc agaaaatcaa catttttcct ctccaaggac
      601 aaggcaattg aatgcaggct ggtgatattg ttattgacaa ctgctataaa cactcctaca
      661 aaaaacaagg gtaaccagta tggaggatga atgtctggaa ctatctgaga atctcggatt
      721 ttggaaatca gactgatcat catgagataa ggaaggaaag cacttgtaaa aagcactgta
      781 atcacgccag tcccctgtcc caagagggtg aggtggtagc gtaaaaccat acggaaaaag
      841 ccctttttag tagttgaaat cctctccttg ctgcgacgtt cttttttgac cttctcctca
      901 ctgttaagca ggatcacgtc ataaaaacga ggaaggacct tctttttggt caggtaaagc
      961 aagaaaacag ttaaagctat ccaagcgagc agacccaata tggcttctat tgaaaaaggc
     1021 tccactgcta ttttgtaaaa gatatgaaga ggataaagga gaaatggaat gtctctaact
     1081 ttgtcaacaa tacttccaaa agtcgactgt agaaagaaga caaatattaa aggtatgaga
     1141 actcctatcc caatcatcac attcgaaaaa atagactgat actttctgaa ggccgtagtt
     1201 tgagccaaga aatgcactgc cactaccatc actagagcca cagagacaaa taataaggtc
     1261 aaggacagta gcatcaaagg caaacccagc caaagagaag gagctagact aatatagagg
     1321 gctagaaaat aagctaggat tggtacaatt ccagttagag ctggaaaaag gacagacagt
     1381 cctttagcaa ttataatctc tgattcttta aaggcatagg gcctatagga ggccaggtcc
     1441 ttactctcat aaaagacatt gtaaaatgca gttaaagaag ttgaaaaggc aatcactagt
     1501 aaaatagcaa ccacgaaact aaaataaaca ggcatttcct caaaaggaaa atgaatggct
     1561 atagtactaa aaaagatgag catcaagaga ctggaaaaaa tgtaagaact taggactcta
     1621 gcggaaacat ttactttttt tccagtattt ttagcttgct tctttcgtag gttagccaga
     1681 ttagcttctt aagatgaata gaggatattg atatcaacta attttttaat gaccttgaga
     1741 cgcatctgaa acctcctctt ttctaccagc aaggctaagg tagatacttt ccaaagactg
     1801 gtctgggttg tcttttctca agtcctctac cttaccacaa taaatcaaat gccccttttt
     1861 caaaatagca atccgatcac agacttgctc agctacctct agcacatgag ttgaaaacaa
     1921 aactgtctta cctttttgcg catgctcctt catcatttgc ttcaaatcaa aggcagcctg
     1981 gggatccaaa ccagtcaagg gttcgtccaa gacccaaata tcaggatcag acaagagtgc
     2041 cccgatgaca aaaactttct gacgcattcc atgagaaagg gtttcaataa cctgataacg
     2101 attttcagca aaatcaaaaa cgttcaataa cctagctaaa ctagcttcca agtcagagct
     2161 gctcaaatca taggatgaag caatcaattc ccaaaattca ttggccgtta aacgtaaaaa
     2221 taagtcaggc gagtctgcta cgtagccaat ctttcgtttg atcgccaagc gattttccga
     2281 taaatcctga ccatctacca aaatacgacc actgctgggt gaaatgatac tgactaggga
     2341 ttttatggtg gtcgattttc cagccccatt atgaccaatc aagcccataa tctctccatt
     2401 ttcaatctgc aaattgagat tactcaaggc ctctttatca ccatacaact tactaacatt
     2461 ttgaaattca atcatgggac aactcctatc tttatctgta ttatatatcg ctatactagc
     2521 actttgatac aaaaaaatca atactttatt ttaagtagtt aaaatagttt ccttctatct
     2581 tacgcaaacg tttgcgctaa tagatacttt atgatagaat aaagaacaag attgacaagt
     2641 aagaggaaac attatgcaaa atcaaacact catgcaatac tttgaatggt atctgcccca
     2701 cgacggtcaa cactggacgc gtctggctga aaatgctcca cacctagctc atctggggat
     2761 cagtcacgtc tggatgccac cagccttcaa ggcaaccaac gaaaaagatg tcggctatgg
     2821 ggtctatgac ttatttgact taggagagtt caaccaaaaa gggactgtcc gcaccaagta
     2881 tggtttcaaa gaagactatc ttcaagccat tcaagccctt aaagcgcagg gaattcaacc
     2941 tatggccgat gtggttctca accacaaggc tgctgctgat cacagggaag cctttcaagt
     3001 tattgaagtg gatcctgtag accgtacagt tgaacttgga gaacccttca ccatcaatgg
     3061 ctggactagt tttaccttcg atggtcgcca agatacctac aatgacttcc actggcactg
     3121 gtaccacttc acaggtacag actatgatgc caaacgccgt aagtctggga tttatctcat
     3181 ccaaggggac aacaagggct gggctaacga ggaattggtc gataacgaaa acggaaacta
     3241 cgactacctc atgtatgccg acctagactt taaacatcct gaagtcatcc aaaacatcta
     3301 tgactgggct gattggttca tggaaacgac tggtgtagct ggtttccgtt tggatgccgt
     3361 taagcatatt gactctttct ttatgcgcaa cttcatccgc gatatgaagg aaaaatacgg
     3421 tgacgatttc tatgtttttg gtgaattttg gaacccagac aaggaagcca atctggacta
     3481 tctcgaaaaa acggaagaac actttgacct tgtcgatgtt cgtctccatc agaatctctt
     3541 tgaagccagt caagctggcg caaactatga ccttcgtggc attttcacag atagcctggt
     3601 tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac cacgataccc aacgaggaca
     3661 agcccttgag tctaccgttg aagaatggtt caagccagca gcctatgccc tcattttgtt
     3721 acgccaagac ggccttccat gtgtctttta cggagactac tatgggattt caggccagta
     3781 tgctcaagaa gatttcaaag aaatccttga ccgcctccta gccatccgaa aagatttggc
     3841 ctatggagaa caaaatgact actttgacca tgctaactgt atcggttggg tacgttcagg
     3901 tgctgaaaat caatccccaa tcgcagtcct tatctcaaat gaccaagaaa acagcaagtc
     3961 aatgtttgtc ggtcaagaat ggactaatca aacctttgta gatttacttg gtaaccacca
     4021 aggtcaagtt acaattgatg aggaaggtta tggacaattc cctgtctcag ctagatccgt
     4081 aagtgtctgg gcagtcaata ccatctaata gctcataata accaagctag gtccaagcgg
     4141 atttggcttt tttgtattca caaaaagacc tacccaaatg gatagatctt tacttgatta
     4201 caatttacct gctactgcat ccaacaattc ttggatctta ggttggttgc ttcctcctgc
     4261 catggccatg tctggtttac caccaccacg tccatcgatg attggtgcta attctttgac
     4321 aaggtttcct gcatgaaggt cttttgtctt gcttgctaca aggacattga ctttgtcacc
     4381 gatagcggca actaggacaa gaagatcaga gtagtctttt tgtttccagt tatctgcaaa
     4441 ggtacgaagg gcacctgcat cggatacaga cacttgacta gcaatgtaac gatgaccgtt
     4501 gacttcctta acatctttga agatatcgcc tgcggctgca gctgcggctt tttctttcaa
     4561 ctcagcattt tctttttgaa gttgacgaag ttgttcttga agtccttcta ccttgtgagg
     4621 tacttccttg acttgaggtg ctttcaaggt tgctgcgaca gctttaagag catcctcttg
     4681 ttcacgatag gcttcaaagg cttccttacc agtcactgcc aagatacggc gagttcctga
     4741 accgattcct tcttctttga caattttgaa gagaccaatc tcagaagtgt tgccaacatg
     4801 agtaccacca caaagttcaa tagagtagtc accaatagtc acgacacgaa cttccttgcc
     4861 gtatttctca ccaaagaggg ccatcgctcc catttcttta gcagtgtcaa tatccgtttc
     4921 aactgtctta acttcaagag cttcccagat tttttcgttg acttgctgtt caatcgcacg
     4981 caattcttca gcagttacag cttggaagtg ggtaaagtca aagcgaagga attcaacttc
     5041 gttaagagat cctgcctgtg ttgcgtggtt tccaaggata ttgtgaaggg cagcgtgaag
     5101 caaatgagtc gcagtgtggt ttttcatgac acggtgacgg cgattgctat caattgccaa
     5161 ggtatattct tggttcaagg caagcggtgc aaggacttca actgtatgaa gggcttgacc
     5221 atttggggct ttctgaacat tggtcacagt agccacaacc ttacctgact catccaagat
     5281 ttgtccgtgg tcagcgacct gtccacccat ttcagcatag aatggcgttt ccgcaaagat
     5341 aagtgaggta gttccttctg atacagcttc tacttctgca ttgtcagcaa cgatagccac
     5401 caatttagaa gacaattggc tagcattgtg gttgaagaca ctttctacag tgatgttttg
     5461 aagagtttca ttttgcatac ccattgagcc acccttgaca gctgacgcac gcgcgcgttc
     5521 ttgttgttct ttcatggctg cttcaaaacc ttcacggtct acagtcatac cagcctcttc
     5581 agcaatttct tcagtcaatt caactgggaa tccgtatgta tcatagagtt taaagacatc
     5641 ttgaccagca atgacagatt gacctttttc tttcaagtct gccacaatgc cttgggcaaa
     5701 gtgttgacct gagtgaaggg tacgggcaaa tgattcttct tcgctcttaa cgattttctc
     5761 aataaagtca cgtttctcaa gcacttctgg gtagtagctt tccatgattt ttccaacagt
     5821 tggaacgagt ttgtaaagga aaggctcgtt gatacccaat ttttgaccat gcatagaagc
     5881 acgacggaga agacgacgaa gaacataacc acgaccttca tttcctggaa gggcaccatc
     5941 accgatagca aatgaaagag aacgaatgtg gtctgcgata accttgaagc tcatgttgtc
     6001 gccatcttgg tcataaacct taccagacaa tttctcgact tcacggataa tcggcataaa
     6061 gaggtccgtt tcaaagttgg tcttagcccc ttggataaca gccaccaaac gctccaaacc
     6121 agcgcccgta tcaatgttct tatgtggcaa ttccttgtat tcgctacgag gaacagcagg
     6181 gtctgcgtta aattgtgaca aaacgatgtt ccagatttca atataacggt cgttttcaat
     6241 atcttctgca agcaggcgaa gaccgatatt ttctgggtca aaggcttccc cacggtcaaa
     6301 gaagatttct gtatctggtc cagaaggtcc cgcaccgatt tcccagaagt tgtcctcaat
     6361 tggaatcaag tgacttggat ccactcccac ttcaatccag cggttgtaag aatctttatc
     6421 gtctggatag taggtcatgt aaagtttttc agcagggaaa tcaaaccatt cagggcttgt
     6481 caaaagctca taagcccaag tgatagcttc gtcacggaag taatccccga tagagaagtt
     6541 ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc cctacgtttt cgatgtcgtt
     6601 ggtacggata gccttttggg cattggtaat acgtggattc tcagggataa tggtcccgtc
     6661 aaagtatttc ttaagggttg ctaccccaga gttgatccac aaaagagttg ggtcgtttac
     6721 aggaaccaaa cttactgatg gttctactga gtgacctttg gtcgcccaga aatcaagcca
     6781 catttggcgt acttgtgcac tagatagttg tttcatattg tctccttatt tacttgttta
     6841 atgtgattgg ctttccagca tttccacata gtcaatcgcg acacagaggg aaatgactag
     6901 gtctgcataa gcgtcctcaa gaaccgttac ggtataggta gaggtcagat ggaagagttc
     6961 cttcttaatt tccgcaatca gctgatcgcg atcatccagc aatttgaaat tcaaatccca
     7021 gatattgccc tcgatacgaa gacctagatt atcaaactca tacttatctc gccagaaggt
     7081 caacttctta cgaatgacaa aactcgagcc atccctaagc tgaatctcaa aacgaggaag
     7141 caaggtcaag atttctttac taatctcact gacttgttca ccagccgcat catagatggt
     7201 aaaggtttta ggaatcttaa aaaatgatcc ctccacctga taggcaattt ctcccctgtc
     7261 atccttgata gcgaagcgtt cgcctccaag acgaaacttt tgtttgacaa gaaatgtttt
     7321 catcaacacc tccaaaaatc aaaagacaag ctcatatcac gaagggcgaa aaaccgcggt
     7381 accaccttca ttcaatgaac ttgtcattct cttgttctta tgcaattgta tgattgagta
     7441 gcatgacttc ctagcttaga tggctcgcag caccgccatt tctctggact aagacaagtg
     7501 aaaatcaatt ctcaactttc ttattataac gtttttttaa gcttgcgtca actggaaatg
     7561 atctccgttg aattagacca attccctaca tctctgatta ctttttcagg atatattttt
     7621 tcttactgcc gtttttcttt ttatcccaaa ttttcatatt actaaacaca gctactagaa
     7681 tatttccaaa tataaaggtg cctatcaccc aatatatgga ctcagttgtt aggtattgtc
     7741 gatccaagcc atcctttaaa tggaatagta taacagtttg gttaacaatc ataaaggttg
     7801 gccagaaact ttttttgaaa aaagtagaca ttttcattat ttgttgccgc tttctgtaag
     7861 gttaatactc aataaaaatc aaaaagcaaa ctaggaagct agcctcaagc tgtacttgag
     7921 tacggcaagg caacgctgac gtggtttgaa gagtataggc ttagtatact actaggcaag
     7981 caaataaaca aataaacaac tagaatagaa aaagataggg ctctaaaaac tgacttctat
     8041 tccttaaaaa cgaaccagct tgactgattc gtcttcttac gtttatctcc tacttccgat
     8101 acattttaaa ctgtaggaag aggtcgctat atttccctgt ccatttatgg tcaaatttct
     8161 cataaacttc taggtgtttc atggtttcaa catcgggata gaaggcctta tcttcctttg
     8221 tttcctctgg gagcaattcc ttcgctggta ggtttggtgt tgaatagccg acatactccg
     8281 cattttggag agcattttca ggtttcaaca taaagttgat aaaggcatag gctgagtttt
     8341 ggtttttaac tgttttggga atgaccatat tgtcaaacca aagattgctg gcctctgtcg
     8401 gtaccacata acgtagattt tcattttttt ctaacatttg gctggcttca ccagagaagg
     8461 tcacgccgat tgcaacatta ttctgaatca tatagccctt catctcgtcc gcaacgatag
     8521 ccttgatatt tggagtcagt ttgtagagct tatccactgt ctcttccaac tgctgcagat
     8581 ccttggagtt gaggctgtag ccgagggaat tgagccccag acccagcacc tcacgcgccc
     8641 catcaaagag catgatagaa ttcttatact ccggcttcca aaggtcatcc caatgctcag
     8701 gcgcttcatc taccatggtt tcgttgtaga caattcctaa ggttccccag aagtaaggga
     8761 tggagaattt attacctggg tcaaaggact ggttgagaaa ctctggtccg atattttcga
     8821 ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc ttcgtccttc atcttgttaa
     8881 tcatgtattc acttggaatg gcaatatcgt aggtcgttcc accctgcttt atcttagtgt
     8941 acatggcttc gttggagtca aaagtctcgt actgaacttg aattcctgtt tcttctgtaa
     9001 actgagtcaa gagttcagga tcgatatagt ctccccagtt atagataacc aatttttgac
     9061 tatctcgact attgatttta ctatctaaat gagtcgcaat tccccacaag acaaggataa
     9121 tcgctgcaat tcctgctaaa aatgaataga tttttttcat gcttgctcct ccttctcacg
     9181 agagataaag taataaccta caactaggat aatactaaag agaaagacta gagcagacag
     9241 ggcattgatt tctaaggaaa tccctttccg tgcacgagag taaatctcga ctgacagggt
     9301 tgaaaagcca tttcctgtta caaagaaggt cacggcaaaa tcatccagcg aataggtgaa
     9361 ggccatgaag taacctgcaa tgatagacgg agtcaggtaa ggaagcatga tttccttaaa
     9421 catctgaaat tgactagctc ccaagtcata ggccgcatga atcatgtcgc cattcatttc
     9481 cttgagtcga ggtaagacca tcaagaccac gataggaatg gagaaggcca cgtgactaga
     9541 tagaacggtc aaaaagccaa gtgaaaactt gagttgggta aagagaatca agaagctagc
     9601 accaatcata acgtcaggcg caaccatgag gatattattg agtgatagaa aggcttcttg
     9661 gtatttctta cgagactggt agatgtaaat ggcaccaaaa gtcccgataa tggtcgctat
     9721 caaggctgat aggaaggcca agaaaaaggt ctgagccaaa atcagcatga gtctcccatc
     9781 tccaaacatg gtttcaaagt gagtccagct aaaacctgta aagctattca tatcatcacc
     9841 agcattaaag gcatagccaa tcaagtaaaa gataggcagg tagaggacca gaaagaccag
     9901 tcccagataa aggttggcaa attttttcat cgttctctcc tttccttagt cacccacatg
     9961 gtgatgaaca tggtcaggat gagaatcaca ccgatggttg aacccatacc atagttgtca
    10021 ttggttagaa aattctgctc aatagccgtc cccaaggtga taacgcggtt cccaccaatc
    10081 aaacgggtca gcatgaagag actcaaactt gggataaaga ccgactgaac cccacttcgc
    10141 acaccgttca tagatagagg gaagatgaca tgacggaagg tctcccactt agttgcacca
    10201 aggtcatagc tggcattgat gagattatta tccatatcgt ctaagacatt gaaaatcggc
    10261 aaaatcataa aggggagctc gatgtagctt gcgacaaaga taaaggaaaa atcggtaaaa
    10321 agcaactgtt gtgaaccaat tccgataaat tccaagaatt ggttaataga gccattttga
    10381 ccaaaaatcc cgataaaagc ataggcttta aggagcaaat tgatccaggt aggaaggata
    10441 atcagcatga gccagagttg acggtgcttg agacgggtca aaaagagggc tgttggatag
    10501 ctgataagca aggtcacaaa ggtcacaatc cctgcataaa gcactgagtt gaaactcatt
    10561 ttaagatagg tcaagttttg tgacgcaaag taagatttgt aattttctaa actgaactgg
    10621 ccttcgatgt tgaaaaagga ttgaccgaaa atcaagacca agggtgccaa tacaaagagc
    10681 gcaatccaaa gcatgtaggg tactacaaag agtttagagc ttgttttctt catctctttc
    10741 ctcctcgatt gcattgatca aacctgcttc ttgctcttcg atttctacgt actcctcaat
    10801 acgagcatcg aactcttctt cggtttcatt gagacgcatg atgtggatgt cttctggttc
    10861 aaagtccaga ccgatttcct cacccacgat ggccttacgg gttgagtgga tcatccattc
    10921 atttccaagt tcgtcatagg cgataatttc ataatgcacc ccacggaaga gctgggtatc
    10981 gaccttaact tgaagcttgc cttcttcagg aagggtaatg cgcaagtcct ctggacgaat
    11041 aacgacctca acaggttcat ttggcttcat cccaccatca accgcttcaa agcgtttgcc
    11101 gttaaattcg accaagtagt cctcaatcat ggtacctggc aagatgtttg actccccgat
    11161 aaaggtggca acaaagtggt tgattggctc atcgtagatg tccacagggg ttccagactg
    11221 gacaatctcg ccatcattca taacgaaaat ccagtcactc atggcaagag cttcttcctg
    11281 atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt tgcagttcac gcagttcgta
    11341 ctgcatgtct gttcttaatt tcaagtccag cgctgacaag ggctcatcca acaaaaccac
    11401 acggggttgg ttgatgatag cacgggcgat agccacacgc tgacgttgtc ctccagaaag
    11461 tttgcggatg gaacgttttt cataaccttc caactgaacc atcttgagaa cttccgctac
    11521 acgttgctcg atttctttct tatcaatttt acgcaagcga agtggaaagg caacattttc
    11581 aaacacattc atatgtggga acaaggcata ggattggaag acagtatgta cgtcgcgctt
    11641 gttggttgga atatcattga tacgaacacc gtctagcatg atatctcctg tcgtcgcatc
    11701 cagtaaacct gcaataatgt ttaggatagt tgatttcccc gaaccagatg cacctagaag
    11761 ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct ttgagaacct tggtgttgct
    11821 gtcttcaaaa actttagaga cgtttttgaa ttcgataatt ggttttttca attggcataa
    11881 attccttctt tttcatagat taaccgatcg gggctctgtc aggtccccac tacctcttgc
    11941 agggagtaaa accacctgca tacatcttcg ctaccgatag gctttcaccc ccctttccat
    12001 gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag atccggactt
    12061 ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat tggatcaagt
    12121 cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca tgcttttctg
    12181 acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt aactgacctg
    12241 caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc aaaggttgct
    12301 tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga tgggttcctg
    12361 gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata gctgaatggc
    12421 ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc ttggtcaaga
    12481 ccttacaaga ctgcaatatg tgagcaatct cgccaccata ggcacccgca ttcataaaga
    12541 cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc aaactatgac
    12601 ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca atggtatagc
    12661 catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga atcccaccat
    12721 cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt tcttggttgg
    12781 caaatttcac aacgcgagcc aactcaaaac gatttcgtgg aaagaccaaa taatcagcct
    12841 ctccacctac ttttgtataa ctatagctat gcaagggttc ctgaaaacgg atatcaattc
    12901 cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt ttacaaaatt
    12961 cattccatta taccattttt agagacattt gacgaccata aaaatacctt gtttggattt
    13021 tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt tccttggttc
    13081 cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact ggatttgtca
    13141 accagcctac ttgggaaaga gatggtgcca gatcaaagaa ggcatgcaag ccataggcag
    13201 ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact gtcaaaagta
    13261 attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc cagaccgaaa
    13321 gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt ggattctgag
    13381 tttgaactgt cgaaagaacg atgtaaagat tgagtaaact agtaaggcct agaaaaatca
    13441 actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc aaacttctct
    13501 ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat gctgccatgg
    13561 ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata ctaccgtctt
    13621 tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa gagacaaaga
    13681 aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt ttggcaaacc
    13741 aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata tgaatggtca
    13801 ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca ttgaacttag
    13861 caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca actgctccca
    13921 cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag gtcaaatcat
    13981 ctgagatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc tcaggcgtcc
    14041 agaaaccaac aatagtcccc acaacattgt cacgactata ttccggttga tgggttgcga
    14101 catcagcaaa cttggtatcg ggtgttgact taggaatcat acgcacatgc atatgtgaaa
    14161 attctccccg aatcttgata gagcggaaaa gattttcccc atcataataa gactcaattc
    14221 gttcttccaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc tctgcctgat
    14281 gcggtactac tgctgcataa ggaataaggg catctggtga cacttccaca atttctggct
    14341 gttctcctgt tccttttgcc tgataagcct tgccatctaa gacaatcaat tccccatcaa
    14401 tagaatccaa ggttcccaaa ccaaggtcac catgctctag caattctccc actgtcatgg
    14461 taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat aatttcactg
    14521 gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat gttactccta
    14581 agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat tgccaagaag
    14641 gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga aacaaagcaa
    14701 gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat ttccgacggg
    14761 tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca aggacaccat
    14821 tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc ctcagagtgg
    14881 ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta ccgacgaaca
    14941 tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg gccgagaaaa
    15001 ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac agtccattca
    15061 caaactcctc tttgagcaag ctctctactg caaggctaac caactagtac tgacttctgg
    15121 aacccaacaa gccttgttta tcctctctca aatatccttt cctagacaag ccaaggaaat
    15181 cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac aggggctgga
    15241 ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg aaggccactt
    15301 caaaacagga aaaattaaat ttttctacac cattccccga tttcactatc ctctgggaca
    15361 ttcctattct gagcaagaca aacgatctat tcttaactta gctgccaagt atgatgtcta
    15421 tatcgtagag gacgattatc tgggtgattt ggactccaag aagggccaaa ccttccacta
    15481 tcttgataca gaggagcgtg tcatttatat caagtccttc tcgaccagcc tttttcctgc
    15541 ccttcgtatt acagcactca ttcttccaaa tgctatcaaa gaagcatttg tggcctacaa
    15601 aaatatccta gactacgaca gcaacctcat tatgcaaaag gccctgtcac tctatattga
    15661 cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat cttaccaaaa
    15721 acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc ccctacacga
    15781 tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac acagtcaact
    15841 gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat ttgccaaggt
    15901 gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg aatgacatcc
    15961 aactctgctt tttcttattc ttcaacttca gttagacttg ctgctttttc aagatagctt
    16021 tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc tttcaaatca
    16081 tcactatttt ttctaagagc aacggcattg gcgtcgccgt ccttcatctt caagctgaca
    16141 gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg ctcatccata
    16201 tgaacagcat ctacttttcc agcctgcaat tcattgactg cttcacccat attagttagg
    16261 gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac agtccctttt
    16321 tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc cacatcagcc
    16381 ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc aaagacttct
    16441 tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc agtttgaaga
    16501 ctggtcaaaa cattgtcaaa actcatgctt gagatttcca acttaacccc aagttcatca
    16561 gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc atcaaccaat
    16621 gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt ccccttttgc
    16681 ttaatggcct caacagctga ctgagaacca ttagaacctg actggcaagc tactaagaag
    16741 aaacttgcaa gaaacttgca agaaaattac ataaaacaaa tatccatttt tttgatttca
    16801 taaataaaca acctctctgt taattttgta taattataac gatatccaag ttacttgtca
    16861 agtgtttttt aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg agccatcagt
    16921 tgatttcaag ctccttttta tacagaatta aactatttta taattcgaca atcttacctg
    16981 tttcaaagta gacaacccat tcacagatat ttttagcata gtcaccgata cgctccaagt
    17041 aggaaataac ttggaaataa tcacgacccg taacaatggc ttctggattt ttcttaatct
    17101 cttcagtcgc aaggtcacgg atagtttcaa aatagtggtt aatttgctca tccatggagg
    17161 ccacccggta tgcatcgtca acagaaccat taagataaag atcaagtgct gcttcaacaa
    17221 cgcttttaac ttcacgtccc atttttttaa tttcttcctc tacagctggg atgcgttctt
    17281 cccccttcat acggatggtt gcctgggcaa tggctacagc gtgatccccc atacgctcca
    17341 catctgatac agccttaagg acagtcaaga ctgtacgcaa atcttgagag actggttgtt
    17401 ggagtgcgat catttcaaat gatttctttt ccagtttcac ttcgtattca tttacttctg
    17461 catcatcttc gatgacctct tttgccaggt cacggtcatg cgtgacaaaa gcacgtaccg
    17521 tacgattgat ttgtgagagc acttcttgtc ccatagcgta gaactggtta tgtaatttct
    17581 ctaaatcttc ttcaaattga gatcgtaaca tctttcatct ccttatccaa attttcctgt
    17641 aatatagtct tccgtttcct tgtgttgggg atcaaggaac atctgcttgg tatcattaaa
    17701 ttcaatcaaa tctccatcta ggaaaaatcc tgtcttatca gagatacgtg aagcttgctg
    17761 catggaacgg gttaccagaa gcatggtgta cttgtctttt agaccataca aggtttcctc
    17821 aattttacca gctgaaatcg gatccaaagc cgaagttggc tcatccaaga ggatgatttt
    17881 aggactagtt gccaagacac gggccacgca gacacgctgc tgttgaccac ctgacaatcc
    17941 aatagctgaa tcatatagac gatccttgac ctcatcccag atagaggcac cttgcaaggc
    18001 tttttctacg gcttcatcca gaacctgctt atccttaatt ccattgatac gaagcccgta
    18061 gacaacattc tcatagatag tcatagggaa aggattaggt tgttggaaaa ccattccgat
    18121 ttccttacgt aattcaaccg tatctgtacg cggactgtag atgttgtggc cattgtacac
    18181 cacggatcca gttgtggtca cctctggatt gagatctccc atgcggttga gagacttgag
    18241 gagggttgac ttccctgatc cagatggacc aatcaaggct gtaatttcct taggttggaa
    18301 agatagggaa acactattca aagccttctt tttattataa taaacggaca ggtctgatac
    18361 ctgtaaaatc gcatctgtca tacggtttcc tttctaacca aagtgaccag atacatagtc
    18421 attggtggac tgtagcttgg cattttggaa aatagttgca gtcttgtcat actcaatcaa
    18481 atcacccaag taaaagaagc ctgtatagtc acttgcacga gcagcctgct gcatattatg
    18541 cgttacaatg atgatggtaa agtttttctt gagctcaaac atggtctctt ctagttgcat
    18601 ggtcgcaatc ggatccaagg ctgaggctgg ctcatccatt aagaggatat ctggcttaac
    18661 agagatggca cgagcgatac agagacgttg ttgctgacca cctgataagg tcaaggctga
    18721 cttgtggaga tcgtctttaa cctgatccca gagggcagcc tgacgaaggg aggtttctac
    18781 gatttcatct aggacttgct tatccttaac tccagcacgt tcatgcgcaa aggtaatatt
    18841 acggtaaatt gacttagcaa atggattggg gcgttgaaaa accattccaa tgtgtttacg
    18901 catttcataa acgttgattt ctggacggtt gacatcaatt ccacgataga gaatctgccc
    18961 agttacttta gcaatatcaa tggtatcatt catgcgattg agactgcgta agtaggtaga
    19021 tttccccgat cccgacggac caatcaaagc tgtaatttta tttctttcaa attgcatatc
    19081 aatcccctta atggattcat ttttaccata gtaaacatgg acatccttag tagaaagggc
    19141 tactttttct tcaggaaagg taaggatatg cttctcatcc cagttatatg ttgacatggc
    19201 ttctccttta ggcagcggtt aatttcttgt gtagatagct tccgaactta cgagctccaa
    19261 agttaaaaat caggataaag atcaggagca cagcggcaga acctgctgat acaatggttc
    19321 catctggaat agtgccttca ctattgactt tccagatatg gacagccaag gtttctgctt
    19381 gacggaagat agagatgggg ctagtcacac tgaggatatt ccagttagac cagtcaagag
    19441 ctggcgccga ttgccctgct gtatagatca gagctgcagc ttcgccaaag atacgaccag
    19501 atgccaagac gacacccgtt acaatacctg gaagcgcttc tggaataaca acatgaacca
    19561 ctgtctccca gcgagaaatc ccaagagcca gaccagcctc acgttgggta tggtgaacgt
    19621 gtttcaaact atcctctaca ttacgcgtca tctgaggcaa gttaaagact gtcaaggcca
    19681 aggcacctga aatgattgaa aatccatact caaactggac tacaaagatc aagtaaccaa
    19741 agagacccac caccactgat ggtaaagagg acaagatttc aatacaagtc cgcacaaagt
    19801 tggtaacagg acctttttta gcatattcag ccaagtaaat cccagctccc atagaaagag
    19861 gtacagaaat aatcaaggta atgaccaata ggaaaaagga attgtaaagc tgaatgccaa
    19921 tcccaccacc tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccaa gagatatggg
    19981 gcaagccccg aaccaagata tagagaatca aggaagccaa gattgtcaca atgatgctag
    20041 caatcgtata gaggacagct gttgcaagtt tatctaattt cttagcgcgc ataatttttc
    20101 tttcctcttt ctttcgtaat caatttaatc acactgttaa aaactaaact catcaagagc
    20161 agtaccaagg ccagtgacca gagaacatta ttatttacag ttcccatgac agtgttccca
    20221 attcccatag ttaatataga agttaaagtt gcagctggtg tggtcaagga agttgggata
    20281 acagctgagt ttccgacaac catctggata gctaaagcct caccaaaggc acgcgccatc
    20341 ccaaagacca ctgcagtgaa aataccagaa cgggccgcct tcaagatcac acgccagata
    20401 gtctgccagc gagtggctcc catagcgaaa ctggcttcac gataataacg aggaaccgca
    20461 cgcaagctat ccgttgtcat aaaggttacg gtcggcaaaa tcatgacaaa gaggacggaa
    20521 atccctgaca aaatcccaaa accagtccca ccaaagacac tgcgaacaaa gggaacgacg
    20581 acttgcaagc caataaatcc atacactact gaaggaatcc caaccaggag ttcaatagct
    20641 ggttgcaaaa tcttcgcccc ttttggtgat acttcggtca taaaaactgc tgcaccaata
    20701 gcaaagggtg ttgcgataag ggctgagaga atggtaacga taaaggaacc caaaatcata
    20761 ggaagggcac caaattcttt actagaagga ttccaagttc ctcccaaaag aaagtcaaag
    20821 atattcacac cattgacaaa gaaggtcgac aagccttttt gcgctacgaa aaccaaaatc
    20881 atggccacaa ggatgactat caaagaaaga caggcaaagg tcaaaccttt tcctaatttc
    20941 tccagacgag aattctttga tggaagcaac attttcttag ctaattcttc ttgattcatt
    21001 attgtctccc ttccaacact gtcacagttc cggcagcatc tttttcaacc ttcatttcct
    21061 taatcggaat atacttcaat cctttgacaa tcccttcttg ggtctcatcc gagagaacaa
    21121 aattgagaaa ttctgcagcc aactcattgg gctgccccaa tgtatacata tgctcataag
    21181 accacaaggg ccaattattg ctacttatat tttctggact taagtcatag ccattcaact
    21241 tcatgctttt gaccgaatca tctatatagg taagagataa ataagagata gctcctggac
    21301 tttttgatac gattgatttt accgctccat ttgaatcctg ctcctgactt tgcatggcag
    21361 actgaccttc cataatgaca gtatcaaagg tagcacgaga accagagccg gctgcccgat
    21421 tgataacaga gatgggtaag tccttaccac caacctcttt ccaattggtt acctcaccta
    21481 tgaagatttg acgaagttgc tctgtcgtta ggttatcaac atcaacctcc ttattgacaa
    21541 tcagagccaa gccagctacc gcgaccttgt ggtcaacaag agcagaagca tcaattccgt
    21601 ctttttcctc agcaaataca tctgagtttc ctatatcaac tgccccagac tgaacctggg
    21661 acaagcctgt accagaacct cccccttgga cattgaccgt ttttccaaca tggatcgtgc
    21721 caaattcatc tgccgctact tcaaccaagg gttgcaaggc agttgagcca acagccgtta
    21781 tggattctcc acgatcaatc cagctagcac agcctactaa acaagccgtc agccaaaaag
    21841 cgataagaga cagagcaagc ttttttcttt ttttcactgt ttttctcctc gaaaataatt
    21901 atgaatactg tgaatttttt aagtagttct ttatgagttg acgcatgaat tcttaccaaa
    21961 tttctgcgca attgattatt tatataatat aggctatatt actctttcct aacctccttt
    22021 tttcatatgt ggataaaatc tcttgtctat cccttccccc attgtcaccc attatagtca
    22081 tttcgtgtct ctttttcccc tttttaatgc aagggaaatt actctcctta gatgataatc
    22141 caaaagctag aaaggtatct caaacctctc tactctccca gactagttta caactaaaag
    22201 gaaaagattc tattttatga gaaatctagt ttacaagcgg taagaacgct aataactaaa
    22261 cttcttgtac tctttgaaaa tctcttcaaa ccagtgtttt gagctatcta tggctagctt
    22321 cctagtttgc tctttgattt tcattgagta gtaaaactac atgtaatggc aatcaagata
    22381 tcaagaatca tcctactaaa aaaatccata ctttcactat aacatagaat aagatatttg
    22441 actagcattt tcatttgaat ctgaggcctt ttggaaaata atttttcaaa acatttccag
    22501 taacctttgc aaagcccaag ccattgcctt taaccaaaac ttggtaccaa ccatttggca
    22561 gactttctgc cagctgaacg atttctccag ccgcatactt gacaaacgct tcttggccaa
    22621 tttcaaccga ctgttcgacc tgactcggtt tcaaggctaa accaagagcg aaactgggct
    22681 caaagcgttt cttcttaaaa gtgcccagat gcagtccatt gcgagcaatc ttgagcttcc
    22741 ctaaatctgg caaaagttct ggcaagagat aaagctggtc tccaaaagtc tgcaagatac
    22801 ccggtagatt gaccttcaaa tggttttggg caaattcctg ccacaaggca acttgttcac
    22861 ggctgaggtt actcttactt gccttaaatt taggagctgg attgttaccc ttaaactgta
    22921 gatgggcaac aaactgaccc tctcccttaa actgatgagg atacatccga gccgtttctg
    22981 gcaggtcaat accagctacc attccattga tatgctctac tggcaacaag tcaaaatcat
    23041 actcttccag caaccaattg acaatctctt cgttttcctc gggtgcccag gtacaggtcg
    23101 aataaaccag atgaccacct tcagctaaca tggtcactgc atcctccaga atttctcttt
    23161 gcaagctagc acattgactc ggataatcta agctccaata gtccatagca tcaggttgct
    23221 tacgaaacat tccttcacca gagcaagggg catcaagaac gattaagtca aaatagcctt
    23281 taaagacctt gaccaagcgg tcggcagatt cattggtcac cacgacattt gtcgctccaa
    23341 aacgctccat gttttcaacc aaaatcttag cccgtttgct tgaaatttca ttggaaacaa
    23401 gtagcccctc ccctgctaga taggctgcca gttgagttga tttgcccccc ggtgcagcag
    23461 ccaagtccaa gaccttcata ccaggactgg gttgggctac ttgagccacc atttgagcag
    23521 caggttcttg cgaataaact aaacctgtag catgctcagg cgatttccct gaaaccttcc
    23581 catagtggcc ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc tcttctttta
    23641 agggattgac ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga aaatctcttg
    23701 cctcatctcc tagtatctct ttatattttt caacaaatcc ttctggaaat tgcatttaag
    23761 ttcttttcct ttcgtaaata taggactgaa tttcctcctg catctcaaga ggcaccatca
    23821 tgaccggctg tctggtttga aaatcaggag cttcaccaaa aagggtcaca acccgatagc
    23881 ccagactttc ccctaaaata ctagctgcgg cataatccca tggttgcaga taagtgagat
    23941 aggtcaacaa acgccctgac aaaatcttgg caaaactaat ggccgcactt ccatagacac
    24001 gaacaccaag aaccgatcgg ctcaaatcag ccagccccca ttcattggtt tccagcatac
    24061 cactattccc tgcaatgaga aaatctccaa gtggtttagt tttaaaagga gctagggacc
    24121 tatcatttag acaaactgga aattccccac caccgtggta acaatcccct ttgaccacat
    24181 cataaatcag accaaactgt ccctgaccat tttcaaaata agccatcata acagcaaaat
    24241 cttcctgctg ggctacaaaa ttattggtac catcaatggg atcaatgacc caaaccttgc
    24301 cctcttgaac cgaggctcgc agacaacctt cttcagcaca aatcttatcc tcaggataac
    24361 gggacaaaat ctcaccaacc aagagttcct gaacttcttt gtccagtctg gtcaccaaat
    24421 ctgttggaga ggacttggtt tcaacacgca agtcttcctg catatggtca agaatgtact
    24481 gacctgcttt cttaacaagc tctttagcaa attcaaattt actttccaag agaaatcttt
    24541 ccttcccctt tttctttggc agcctgaact gctcggtaaa gtgaatagcc actaaccgtt
    24601 tcaaattctc gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc tttgaatccc
    24661 ttataggagt ccagtaactt tttagcctct actttgcctt cataggcagc ttcaacatca
    24721 ttaaaaaaag aaagcactga agcaagttct tcagtgctcc acgacaaatc tagtgggtaa
    24781 ctatactgtt tgttcattaa ctaataccag ctctcattct tgcttctttt agttcttgct
    24841 tacgataact acgagggaga aaagcacgaa tctcatcttc attaaaaccg atttgcatac
    24901 gcttggcatc aataataatt ggacgacgca aaagactagg atactgctca atcaaatgaa
    24961 gcaattccga taccgaaata ctctctacat caatattcaa tttttgaaaa atttttgaac
    25021 gagttgaaat gatgtcatca gtaccatttt cggtcaagga aaggatgtgt tgcaattctt
    25081 ttcttgttaa aggactggtc ataatattgt gttccacaaa gggaacctta tgtttttcta
    25141 accaggcctt agccttacga catgatgtac agctcggtga tagaaatagt gtaatcatgc
    25201 ttttctcttc ttatctatac tttgctactt ctattataca aaaaaataag gcgcttgact
    25261 agggattttt agaaaaaaag cctatttttt caggaaaaat aggctgtttg cgaacgattg
    25321 acacaattgg atttggttaa ttcactctta acgatggttt taaacgatat gtatatattt
    25381 atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag acacagatag
    25441 ccaaagaagt tttcatagag ggcaaaaaag aggaggaagg catgaagaaa gaaggtctct
    25501 ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc atctcccaca
    25561 aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac tcccccaagt
    25621 ccaatcatta caggtaaaac tactagagcc aggagacttt ttcgataaag agacaaaaag
    25681 tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac tagagctact
    25741 agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcagacc agctgctgac
    25801 gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata attcatcaag
    25861 atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt taagtttagc
    25921 cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag gatggagagg
    25981 gagaggagaa agagcataga gccccaaaag atcaatttag ttttcatcaa aatcccactc
    26041 cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt cttctgcctt
    26101 agtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag cccgaatatc
    26161 agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta agtgctcaac
    26221 cgccttgtcc ataatgatgg catttggttt tccgatataa accggcttca ctcgtgtcgc
    26281 tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccgcgtt ccgtcgggat
    26341 gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa gagttgctgt
    26401 ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg caggtttttc
    26461 cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt ctccgacgac
    26521 atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca aagtcgctgt
    26581 gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct ccttaacact
    26641 ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc gcttttgcaa
    26701 ttcatgaaca aaagtctctc cagcagggat tcggtctttc cccttataaa tggttccgtc
    26761 taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt tttatttctt
    26821 gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca tgcttgcttt
    26881 ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact tccttgacat
    26941 acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc atgacctcaa
    27001 aaatccagtc caagtattta ctgttattga catgaccatt catatccaag tcgtaaaaac
    27061 gaacatggta atccttgctg atcggttctt ccaaggactc atacttcggt ccacggataa
    27121 gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca acatggactt
    27181 ttcgactgtc gcggtccatg agaacaaagg tcgccatcat gtggatgagc tcctgctccg
    27241 cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc aaggcttccg
    27301 tttcgatggt aatttcttcc gcaaaacgag gcaaacgaaa cacctcaata tcatattcta
    27361 cgataatcca gaccagatta tattcttcca aaatggcctt atcactaact cccagttcaa
    27421 tcgactgcat ccctgaaact tgcagtgaca gcaaaatcac atctggaagt ttgatatgac
    27481 cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt aagcccatga
    27541 tcctactcca aaataaatcg ttctgctaca gtatctccca aaaagagacc tctctttgtc
    27601 atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc tctgacaatt
    27661 tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc catggaaacc
    27721 ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt ttgactcagg
    27781 tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg acgaatggga
    27841 ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc aataccatag
    27901 tattcagcat tgtcccagta catgagatta tgacgacttt caaagccggg tttggagaaa
    27961 ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat gtactcaaac
    28021 atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat ccggttcata
    28081 aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat atccaatcca
    28141 atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag agcataaatc
    28201 aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt ttcataaata
    28261 tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa ggtctggaca
    28321 cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc cgcatccaaa
    28381 tcgcctggat tggcttcaat ggtcaactct tccaagacag acaaatccaa gtttttagtc
    28441 aagccattca gtaacacctc cagttgcgga gccgacaggg ctgtcggtgt tccaccaccg
    28501 atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag cagatgctct
    28561 aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca ataataacaa
    28621 atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg catagtaatt
    28681 attataccac aaagactaga ttccagataa aaatcaccat ccccagatac atagtccgtc
    28741 cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct gagtcatcaa
    28801 gagcttcggc tttttcttgc cattgttcct tgagattatt taattgattt tttgatgctt
    28861 ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca gtgatttcac
    28921 ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc ttaacttctg
    28981 tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa tcatctagaa
    29041 aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac aaggcaagag
    29101 ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg attctccttt
    29161 tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca ccagtcttga
    29221 gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg tcattgaggt
    29281 ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc gtagccacct
    29341 tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg gtgtgatgca
    29401 aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca tcgatgacac
    29461 gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaca gctagggcaa
    29521 caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag taaggggcct
    29581 tctttcgatt ttgataaata acgatcatta taccgagacc gataaagaca actgacagcc
    29641 attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct tcgatgacca
    29701 tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt ctgagactct
    29761 tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat agagactcat
    29821 aaaggaaagt cggttgatgg tagctcccct caatatacat ctggtcacgg ataaagccag
    29881 gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag aaattacccc
    29941 aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga aaatcccaag
    30001 tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt atcaaaccac
    30061 cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc tgactatagt
    30121 aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag ggaaaggcta
    30181 ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct tctttcatgg
    30241 tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa cgaatggcta
    30301 ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg agctatgaga
    30361 cttgtcagtc gttcgtcgaa caaacgggta gcatcaaagc ccatttcctt ggcacgataa
    30421 ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac tggaatacga
    30481 atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc aagacgatca
    30541 aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg tgaagaatcc
    30601 ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc acgaatttca
    30661 atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc cttggcaaag
    30721 atatcgacac ggtcatcggc taccaaacgg tgaccacgtt tgacaagctc aagacctgtc
    30781 tcgctcttac caattccact atctccctga atcaagacgc ccatcccata aatatccatc
    30841 aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct agataactct
    30901 ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca ttctctagca
    30961 gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc tggtgtctca
    31021 ggtagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct gatcagataa
    31081 gaccactcct tcatccccaa aagttgaatc cgctctggtg tatagtagtc aaaatagcct
    31141 gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc aagcaattct
    31201 ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac taaaaccgac
    31261 atcatttcct ccttcaaatg aattcttctc tctattatat caaattgtag gaggaagttt
    31321 cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat ttctctagcc
    31381 tttcatttca attagaattt tttacgttta cgagctactt ctgatttacg tttacgtttt
    31441 acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc agctttagta
    31501 accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg tactactgtt
    31561 ttagacattt ttttcactcc cttcaagttc aatatctatt tcattctaca cgtaaaagga
    31621 ataattgtca agcaaaaatg cggtttaatt ttgatttttt cttccattta tacaagagtt
    31681 gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg cttcagcatc
    31741 tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt tctcagtcac
    31801 tgggccagat actgttccgg caatggcttc tgctttcgac tcaccataag caaaaagaat
    31861 aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg ttgggacgtc
    31921 ttcaatcttg gcaaagaagc gagcattggc ttcgatagta gactggtcaa gttctactag
    31981 atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc cattgcgacc
    32041 gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt agcgttcaac
    32101 ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa atggtttttg
    32161 gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc catcaaggcc
    32221 cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac tctcaacaat
    32281 ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt gagctccatt
    32341 agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt ggttttcaac
    32401 tttaataact ttcatctttt catcctccat ttctgtctat atttattata tggtatagac
    32461 caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa acttgaaacg
    32521 tgttataatg gataggatta gaacttagaa agaatgaaca aatatatgaa tacagctgat
    32581 tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa acgtgatgcc
    32641 tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca tttccactct
    32701 attattgata tgctggaacc tggtgatgcc cttgtcatga acgacacccg agttctccct
    32761 gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct cctccttaag
    32821 aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct caaggtcggt
    32881 actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga attgacccac
    32941 ggaggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt ggaaagtctg
    33001 ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga acgttatcaa
    33061 accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct tcacttcacc
    33121 aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct gactctccat
    33181 gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca cgaaatgcac
    33241 tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt caaaaaaaat
    33301 ggtggtcgtg tcatcgctgt cggaaccact tctatccgca ccttggaaac tattggttcc
    33361 aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat caaacctggg
    33421 tatgagtgga aggtcgtgga tgccttctca accaacttcc acctgccaaa atcaactctg
    33481 gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta ccaccattcc
    33541 atccaagaac actaccgctt cttcagtttt ggtgacgcca tgtttattta ttgagaaaga
    33601 atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa gaacatctac
    33661 aattgaaact ctagctagct gtagaagagg cctagtacat tgaaattaaa atgcttcccc
    33721 ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc atctatattt
    33781 tatttcagct tcctatactt tcttcgctgt ttgtaaatca aaatgcaaga cacatgagta
    33841 gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt atttcagaat
    33901 cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta tactcttcaa
    33961 aaatctcttc aaaccgcgtc aacgtcacct tggattatat atgtgactga ctttgtcagt
    34021 tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc tagtttgctc
    34081 tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa tgtacagaag
    34141 actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata gctttttata
    34201 tataattata tattcagaca tactattatc aattttgtcg cagggaggaa tctgttaacg
    34261 cacccattca ccattatcat tgactctata gccatctata cttgtattga ccgctaactc
    34321 acccgatgta tttacataat accatttacc accaacttgg aaccattgat tgactttcat
    34381 agaaccgttg ctgttgaggt agtaccatga accattaact tgtacccaac ctgttgccat
    34441 ggaaccatca gtattataaa aataccacat accattttct tgtttccagc ctgttgttgg
    34501 agcaactgct ttagctggtt ctactgctac atctgttcct tggttagatg taacagatac
    34561 aggatacgaa ggaatagatg attgctcagg aacaacaact ttttcaggtt ctctcgtccc
    34621 tctccttata cgtcttttta ccatctcttt agtaatttga cgagaagtag tttcttcaat
    34681 tgttccatca cgttcatcta cagcatagat tgtagtaaga gtaattttac caatttctcc
    34741 tacttcttga cctttatcaa gagttgggtc atcgagatat tctgtttcga ttggaatttc
    34801 ttggacaata acttggggct tggttccttt tttaacaact cttgtttgag agtcttcttt
    34861 ttgacttaaa gtactctcag ttacttgtcc actctttcca tctacatcat aagttatcgt
    34921 tgtaactgtt ttcccattct ttcctagagt aatctcttgc tcctgtcctg cagaaaggtc
    34981 attgtctgct tcatatttag tagcacatgg aacaagaact tcttcaacct tgcttttagc
    35041 tggaactttg ataactgtat ccgtggcttc ttttctatca acagtaacct tttcggtaac
    35101 atgaccagtc tctggattaa catcgtaggt ccttgtcgtg gttacatagc catcctctcc
    35161 gtcaattgta acaggatttt cactacggta ttttgtttca tctttttcaa aacgaattcg
    35221 cgtacttgaa attttcttgg ttactacctt aggtttagtc gctactttta caataatatc
    35281 cccattgtca gcgtcatcat actctattcc ctcttcttta tctctagtat catctctgac
    35341 atattgaatc ccatcagcag catgagcaaa acttgtattc agattcctcc taaaaataaa
    35401 gttagcccga ttaccgcaga accaaaaatc tttccgagtt tacgtattgc atagcgctta
    35461 ttagtattag attttgccat tacatcctac ttctagtata gcatcttttc tatcaaacgt
    35521 taaacaatat actttatata taaaatagac ttagaatgat atatttacta ttgaactaac
    35581 actttaacta tatcgtaatc aatctcatat ataaaggatt gcagacatct gatctaaata
    35641 catgctaata tatttagata caaacattcc aacttgataa ttttcactca tctttcatca
    35701 ttccttacac aacgatgcag tataaataga atagttttct catcagaatg agactatttt
    35761 aatattagat aatttgatag aaaaaacata aataaaattg gttgaattta attccctaac
    35821 tcgatagagg attctatttt aaatttaaca acagctagga ttacactata aaaagtacat
    35881 taccacctgt tcggctggag aatctagtcg attagctccc tcttagttac aagcttaaag
    35941 cgatttttta actaatacta aaccagatta aagaaggaac tagaacatct gtcttgtact
    36001 aatcaatatg ctattttaaa attgcaaata aacttggaat gctaattatt atatttacaa
    36061 taaatagttg acttcgatag aaacagaaaa tagaattcaa cattcttccc tacttatacc
    36121 ataataaata agatccgcaa gatagccttt tctctctaca ccattaacaa tggtttgtag
    36181 ataggacatt ccagcctttt ccatgacacg acctgaagct gggttgagac tggcataacg
    36241 tgctctgacc ttttgaaaac ctgcttgagt aaaacaaaag tccaagacag ctttcaaggc
    36301 ctctgtcatc ataccatgtc cccagtaagc cttgcctagc acatagccga tttcacagct
    36361 taaatcagcc tcgtctatct taacgatgct gatatctcct atcacttgct ctgggttttc
    36421 ttttagacaa atggcccatt tgtaatagtt gagattagta taggaagcaa cccaattgcg
    36481 aatcgagttt cgagtgattt cgacatcagg atggggatcc caggtaacat aggtcagatt
    36541 ctcagcggat gaagcccaat tttgaaacat ggcttctgca tcactctcca caaatcttct
    36601 taaaatcaaa cgttctgtct gtaatatttg cgtaccaata gatttcatga tgctacctca
    36661 cttccttatt tctatgctcg tagtaaaaag gctcaactca gtaacagcta gaaaacgagt
    36721 ttgtcttcta atttcttgac gcagtcgctg cctggtttga aatgcgatct agcaagcttt
    36781 ttcaaaccta gtcatcgttg caggggtaag acgatgaaat cgaactcttc gagttaccga
    36841 atctgcctca ttttcttatt tctaaactcg aggttcaaga tcccccggac cttctctcac
    36901 tttcttattt caagatgaga ggctgaaaac ctccagtgga ggtttttctt gctttttaat
    36961 ttcagggcaa gaagctaaaa aggtcccccg gaccttttta ctcccaaaag tcatcaaata
    37021 cggtgatggg taagtggcgt ttgtgttggc ctttgtgcca ccagttttca atggtcgctt
    37081 gagcttctgg gctgattgtt ttgccttcta ggtagtcgtc aatctctgcg taggtgactc
    37141 caagtgcgac ttcgtcagct aggcctggtt tatcttcttc taggtctgcc gttgggattt
    37201 tttcataaag ggctggctct gcgccaagtt tctgcaagag ctgttttcct tggcgtttat
    37261 tgaggcggta aagagggaga atatccgcac cgccgtcacc aaacttggta aagaaacctg
    37321 tgatattttc tgcggcgtgg tctgttccaa tgaccgctcc gctatgggaa ccagcaaggg
    37381 catactgagc aatcatacgg caacgtgcct tgatattccc cttgttgaag tctgaaacag
    37441 gactacctgt cgcttcaact gcagctgtca tggcatcagc tgattccttg atattcacaa
    37501 ccaagctgac atctggctgg atgaaggcta gggctttttg agcatctgct tcatcagctt
    37561 gcactccgta tggcaggcgg acagcgataa atttgtagct gtcgtctccc gtttcagctc
    37621 gcagttcttc tatagctaat tgcgccaaac gtcctgccaa ggttgagtct tgtcccccag
    37681 aaatccctag tacaaaggtt tttaggaagg gatgtttttt cagatatctt tttaagaaat
    37741 caatagaacg acggatttct tcctgggcat caatcactgg tttgacaccc agctcttgga
    37801 taatcgtttc ttgcaaactc attcttcttc tccttcacca agggcttcct tgcgcatctt
    37861 atcaatcaag tccatcttat cttgccatac atcacgtgcc aaatccactg gatagtgctg
    37921 cggattgagc acacgcttat actcatccca caacttgtca aattctttac gggcataatc
    37981 ctgaatgtca gtcaaactag gcaagttgta aactaatatt ccttctttga agatatccac
    38041 caagagagga acggcatcaa aattacgaac cgtcttcttg atgtatgtat aggtcggatg
    38101 gaacatcttg atttctgtca tgtcgctaat atccacacca tcataagtga tgtagtcacc
    38161 ttctgacttg cctttttcac gactggtaat gcgccacacc tgcttcttac ctggcgtcga
    38221 cactttttcc gcattattag acagcttaat cgtattgcgc atctgaccag tttcatcttc
    38281 aattgcaaca atcttgtaaa ccgccccaag agccggctgg tcataggctg taatcagctt
    38341 ggtacccaca ccccagacat caatcttggc cttttgcatc ttgaggttaa ggatggtatt
    38401 ttcatctaga tcattagaag cataaatctt agcctctgta aatccagcct cgtccagttg
    38461 ctgacggact ttcttagaaa tgtaagcaat atccccagag tcaatccgca cacccataaa
    38521 gttaatctga tcacccagtt cacgcgccac ctgaatggca gctggtacac cgatgcgaag
    38581 ggtatcatag gtatccacaa gaaagacaca atttttgtgg gtcgcagcgt aagccttgaa
    38641 agcctcatag tcattgccat aaacctgcac caaggcatgg gcatgggttc ccaaaacagg
    38701 aatgtcaaag agtttacccg cacgcacgtt gctggttcca ttggcgccac caatcaccgc
    38761 tgcacgtgtt ccccagatgg ccgcatccat ttcttgagcc cgacgtgtcc caaactccat
    38821 caagggttca tcttcgataa ccgaacgaat acgagctgcc ttcgtcgcca ccaaggtctg
    38881 gtagttgacg atgttcaaaa gagccgtttc gaccaactga cattgggcta gaggtccttc
    38941 cacctgcaca atcggttcat tagcaaaaac caaatcccct tcttgggcag aacgaacggt
    39001 caactccaac ttgaaattgc gaaggtaatc caagaacgcc ccatgataac caagcgactc
    39061 caaataggct atatcactat ctgaaaaacg caagtcttca agatagttca caattctttc
    39121 caaacctgca aaaaccgcat agccgttctt aaaaggctgt tggcggaaat acacctcaaa
    39181 gaccgccttc ttattgtgaa tcccttggtc aaagtaaacc tgcatcatgt tgatctggta
    39241 caagtccgtg tgcaatgtca aactatcatc tggatacata cttttcctac ttccttagct
    39301 agaaacccat gaaaattttc aagaactttc atgtattcca ataaattagt actattatat
    39361 cacattttag ctggattgag aaaagagtaa caagctattc tccactctcc aattcatcca
    39421 tatcttgttc aaattttttc tgagcccatt cgccatagct cttaagacca agattgccaa
    39481 taaagaccca cggaaggtaa atgacataag taatgaccca agcagacagg tatttaaaat
    39541 tcaaaggatt gtgctgataa atttctatgt tgaattgata attctgcaac atcaaaagag
    39601 ccgtaatagc caaggttagg aaaaaacaac ccaaaatcgt aaaatgaaaa cgactatagt
    39661 aggtcactcc cagataacgg gcacgattga aaaagtaaaa tgttcctatg atgataacga
    39721 ttagcagcat attagaatta aaaaggcttg gtgctaatac tgaaatgata taagatagga
    39781 gcgacaaagc gatgcagata tagaaacttt cagagcccgc tttattgaac agttgttctt
    39841 ctctttcgtc tagtaattga taataataaa atctattttt catcttcttc ctcccaaaat
    39901 agttggtcta gggttttccc taaacatctg caaatggact ggcagagcga gagactggga
    39961 ttgtatttcc ccgcctctat caaaccaata gtctggcgcg tcaccccgac agcatctgct
    40021 agttgacctt gagttaaatc aagctctacc cgagctaatt ttaattttaa atttttagcc
    40081 accttcgtcc tccttatagt tttaatactc atctactctt aaaaaatcca aaaccaacac
    40141 aagctatcag ctatttatta taaccccatt aatttgcact ccagtattat cttcagccga
    40201 aaatcagtat tttaggttgt ttgaaataaa cttcctagtt tactctttta tttttattta
    40261 gtattagctt tagtagaatc ttttaaacga gtttttattg cttatatttc ttgtttagtt
    40321 tagttggttt catatcacta ttatataatg cttttggaaa tgagcctagt ataagtcaaa
    40381 aacgtgttga atagtgaaag caggagcata ccaagatgac tgattttttt attgtatttt
    40441 aggtatgcaa aataatacta aatgaaacta aaatgaatac ttcttgcttt tcttgagagt
    40501 gaaaaagtac aataaaatga ttgtagtgat tagcacaaga tactgactaa tagacatcgt
    40561 atttgaagcc acaaatacag gtaaagaata aaaaggaaga agttcaattg ctttgataaa
    40621 caaatcatta ctagtattca tcatcatcgt atttaatata ttagggataa agagtagtaa
    40681 agctactaaa ataccaaata ccaagccact tttcaatttg tataaataga aaatgtaaga
    40741 taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta ctataaaatc
    40801 taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca caatgccatt
    40861 caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga cgtaaatcat
    40921 ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat ctctactaat
    40981 gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa agtttgaaat
    41041 atgcttaata ccaagcgatg tcccttgagt ctttagaata aagaatgtaa gcaatatcgg
    41101 cggtataaac gagataagca aactgagata tattacgcct gatgaatata aatttcttat
    41161 attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc tttattttga
    41221 acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa ctactttaat
    41281 agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag acatagtaat
    41341 tctcagtccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga aaatgtctct
    41401 atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt ttcctacttt
    41461 ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt cttcaatgtc
    41521 ttctaattta tgactcgata ttaaaattcc cacattttca tgtaaagcta atttttttag
    41581 aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt catctaaaat
    41641 caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt ttgtacccaa
    41701 agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt ggatcaaaca
    41761 tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt ttaaattctc
    41821 taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa cattatcact
    41881 gcttataata ttacctgaag tcggttgatt attctgaaca agaattttca tcaacgtact
    41941 cttaccaact ccatttctcc ctgctagacc aacaatttca cccttgttaa gtgcaaaatt
    42001 tatatctttg agaatgattg aatgaccata atgcttactt acatttttta ttcctccatt
    42061 aatattattg gttttctctt tgattctcat taattttaaa aagttgcgcc tctttttaa
//
LOCUS       DAVKZI010000016        41659 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKZI010000016 DAVKZI010000000
VERSION     DAVKZI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.016"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            21..401
                     /locus_tag="VXB18_000978"
     CDS             21..401
                     /locus_tag="VXB18_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382197.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGVAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            595..885
                     /locus_tag="VXB18_000979"
     CDS             595..885
                     /locus_tag="VXB18_000979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382198.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            936..1628
                     /locus_tag="VXB18_000980"
     CDS             936..1628
                     /locus_tag="VXB18_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0382199.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1681..3114
                     /locus_tag="VXB18_000981"
     CDS             1681..3114
                     /locus_tag="VXB18_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0382200.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMM"
     gene            3178..4092
                     /locus_tag="VXB18_000982"
     CDS             3178..4092
                     /locus_tag="VXB18_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-fucosidase"
                     /protein_id="HEV0382201.1"
                     /translation="MLRETVRFWNAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQS
                     LIWQLFHDFIQAAQELGLDEDLLTEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNE
                     KVEAQHRHASHLVGLYPGNLFSYKGQEYIEAARASLNDRGDGGTGWSKANKINLWARL
                     GDGNRAHKLLAEQLKTSTLPNLWCSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAA
                     LPDAWSTGSVSGLMARGHFEVSMSWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMN
                     QEKIKAKCMGKDCISVATAEGDLVQFYF"
     gene            4342..5043
                     /locus_tag="VXB18_000983"
     CDS             4342..5043
                     /locus_tag="VXB18_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382202.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5045..7753
                     /locus_tag="VXB18_000984"
     CDS             5045..7753
                     /locus_tag="VXB18_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0382203.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7849..8340)
                     /gene="tpx"
                     /locus_tag="VXB18_000985"
     CDS             complement(7849..8340)
                     /gene="tpx"
                     /locus_tag="VXB18_000985"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0382204.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8463..9392)
                     /gene="psaA"
                     /locus_tag="VXB18_000986"
     CDS             complement(8463..9392)
                     /gene="psaA"
                     /locus_tag="VXB18_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0382205.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9424..10272)
                     /locus_tag="VXB18_000987"
     CDS             complement(9424..10272)
                     /locus_tag="VXB18_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0382206.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10269..10991)
                     /locus_tag="VXB18_000988"
     CDS             complement(10269..10991)
                     /locus_tag="VXB18_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0382207.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11282..13174
                     /gene="pepO"
                     /locus_tag="VXB18_000989"
     CDS             11282..13174
                     /gene="pepO"
                     /locus_tag="VXB18_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0382208.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13297..13926)
                     /locus_tag="VXB18_000990"
     CDS             complement(13297..13926)
                     /locus_tag="VXB18_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0382209.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14885..17107
                     /locus_tag="VXB18_000991"
     CDS             14885..17107
                     /locus_tag="VXB18_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0382210.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17137..17580
                     /locus_tag="VXB18_000992"
     CDS             17137..17580
                     /locus_tag="VXB18_000992"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0382211.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17847..18032)
                     /locus_tag="VXB18_000993"
     CDS             complement(17847..18032)
                     /locus_tag="VXB18_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382212.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(18051..18464)
                     /locus_tag="VXB18_000994"
     CDS             complement(18051..18464)
                     /locus_tag="VXB18_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382213.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18595..19242)
                     /locus_tag="VXB18_000995"
     CDS             complement(18595..19242)
                     /locus_tag="VXB18_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0382214.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(19419..20069)
                     /locus_tag="VXB18_000996"
     CDS             complement(19419..20069)
                     /locus_tag="VXB18_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0382215.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20181..21023
                     /locus_tag="VXB18_000997"
     CDS             20181..21023
                     /locus_tag="VXB18_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0382216.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21099..21536
                     /locus_tag="VXB18_000998"
     CDS             21099..21536
                     /locus_tag="VXB18_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0382217.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21604..21906
                     /locus_tag="VXB18_000999"
     CDS             21604..21906
                     /locus_tag="VXB18_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382218.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(21997..23070)
                     /locus_tag="VXB18_001000"
     CDS             complement(21997..23070)
                     /locus_tag="VXB18_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0382219.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23226..23903
                     /locus_tag="VXB18_001001"
     CDS             23226..23903
                     /locus_tag="VXB18_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382220.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMKVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23896..24870
                     /locus_tag="VXB18_001002"
     CDS             23896..24870
                     /locus_tag="VXB18_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0382221.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(24919..26862)
                     /gene="thrS"
                     /locus_tag="VXB18_001003"
     CDS             complement(24919..26862)
                     /gene="thrS"
                     /locus_tag="VXB18_001003"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0382222.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(26920..27243)
                     /locus_tag="VXB18_001004"
     CDS             complement(26920..27243)
                     /locus_tag="VXB18_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0382223.1"
                     /translation="MELQELVERSWAIRQTYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            28113..28742
                     /locus_tag="VXB18_001005"
     CDS             28113..28742
                     /locus_tag="VXB18_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0382224.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28883..29152
                     /gene="rpsO"
                     /locus_tag="VXB18_001006"
     CDS             28883..29152
                     /gene="rpsO"
                     /locus_tag="VXB18_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0382225.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            29967..30581
                     /locus_tag="VXB18_001007"
     CDS             29967..30581
                     /locus_tag="VXB18_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0382226.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30874..31623)
                     /locus_tag="VXB18_001008"
     CDS             complement(30874..31623)
                     /locus_tag="VXB18_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0382227.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31756..34092
                     /locus_tag="VXB18_001009"
     CDS             31756..34092
                     /locus_tag="VXB18_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0382228.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKMF
                     GASQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            34621..36084
                     /locus_tag="VXB18_001010"
     CDS             34621..36084
                     /locus_tag="VXB18_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0382229.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            36077..36505
                     /locus_tag="VXB18_001011"
     CDS             36077..36505
                     /locus_tag="VXB18_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0382230.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            36483..36932
                     /locus_tag="VXB18_001012"
     CDS             36483..36932
                     /locus_tag="VXB18_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0382231.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            36960..37271
                     /locus_tag="VXB18_001013"
     CDS             36960..37271
                     /locus_tag="VXB18_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV0382232.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            37297..38382
                     /locus_tag="VXB18_001014"
     CDS             37297..38382
                     /locus_tag="VXB18_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEV0382233.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILRKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            38393..39088
                     /locus_tag="VXB18_001015"
     CDS             38393..39088
                     /locus_tag="VXB18_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0382234.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            39125..41095
                     /gene="tkt"
                     /locus_tag="VXB18_001016"
     CDS             39125..41095
                     /gene="tkt"
                     /locus_tag="VXB18_001016"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0382235.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            41465..>41659
                     /locus_tag="VXB18_001017"
     CDS             41465..>41659
                     /locus_tag="VXB18_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0382236.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFGKKGKNRYYSPDLKQE"
BASE COUNT        12224 a         7639 c         9441 g        12355 t
ORIGIN      
        1 ataaaaaagg agattttatt atgaaattaa aaacacttgc tttaattagt ggtatcgtcg
       61 gtcttgtggg aggaatttta cttcttattg gtccttttgt cttgttggga acagcggtaa
      121 acacagttgc tacaactctt aatggaggag ctactgcagg ggctttttca ggtgttgcct
      181 tactcttgaa tgccttgaag attgcaaatc ttgttcttgg tatcattgct attgtttact
      241 ataaaggaga taatcgtgta ggtgtagctc cgtctgtact aatgattgtt tttggtggag
      301 ttagtctcat tccattctta ggatgggttg gggggattct tgttattatc ggaggatctc
      361 tattccttgc aacattgaag aaattcaaat cagaagaata aaaggtattt tagcatgaaa
      421 agaacaaaaa agtttatcgg tataggagta gctctattat ctctttttct tctagttgca
      481 tgtggaacat aaagttcaaa ggatacttca acaagtaatg atgagaagac agtagcaaca
      541 tccaatagtt caaaagaaac aatcactttc gatacaccgg ttgtaacaga cgatgtgatt
      601 gaatcaatac gcacttatgc agattatata gatctttata aaaatatttt tgatgattat
      661 tttactaaag ctgaggaagg tttcaaaggc acagctatgg aaaataatga ctcgtttact
      721 aaactaaaag agtcaactca aaaattattc gatgcgcaga aaaaaaggtt aaataatgaa
      781 gatagaatag aaacaactaa aaacaatgtg attgccaaac attgtcaaac agtcctttcc
      841 tttttggttt tgactagctt ttttgtgaaa aattgtgtaa aatagaatag ataaacgagg
      901 ggaaacctcg gaaaatttaa aggagaatcc atctaatggt aaaattggtt tttgctcgcc
      961 acggtgagtc tgaatggaac aaagctaacc ttttcactgg ttgggctgat gttgatttgt
     1021 ctgaaaaagg tacacaacaa gcgattgacg ctggtaaatt gatcaaagaa gctggtatca
     1081 aatttgacca agcttacact tcagtattga aacgtgctat caaaacaact aacttggctc
     1141 ttgaagcttc tgaccaattg tgggttccag ttgaaaaatc atggcgcttg aacgaacgtc
     1201 actacggtgg tttgactggt aaaaataaag ctgaagctgc tgaacaattt ggtgatgagc
     1261 aagttcacat ctggcgtcgt tcatacgatg tattgcctcc aaatatggac cgtgatgatg
     1321 agcactcagc tcacacagac cgtcgttatg cttcacttga cgactcagta atcccagatg
     1381 ctgaaaactt gaaagtgact ttggaacgtg ctcttccatt ctgggaagat aaaatcgctc
     1441 cagctcttaa agatggtaaa aacgtattcg taggagctca cggtaactca atccgtgccc
     1501 ttgtaaaaca catcaaaggt ttgtcagatg acgagatcat ggacgtggaa atccctaact
     1561 tcccaccatt ggtattcgaa ttcgacgaaa aattgaacgt cgtttctgaa tactaccttg
     1621 gaaaataaaa aattgtaagt ctagaattga tttctaggct ttttatgtta gtatggaagt
     1681 atgataagga ataaaaaaca agattatgta ctggcctaca agcaaccagt ttcaaccact
     1741 tacatgggtt gggaagaaga agctttaccg ataggcaatg gttctttagg agcaaaagta
     1801 tttggcctta taggggctga acggattcaa tttaatgaaa aaagtctctg gtctggaggt
     1861 ccacttcctg atagttcaga ttatcagggt ggaaatcttc aggatcagta tgttttttta
     1921 gctgagattc ggcaggcttt ggagaagaga gattacaatc tggctaagga actggctgag
     1981 cagcacctaa ttgggccaaa aacgagtcaa tatgggacct atctgtcttt tggggatatt
     2041 cacattgagt tcagccagca aggtacgact ttgtctcagg tgacggacta tcagagacag
     2101 ctgaatatta gtaaggcact tgtgacgact tcttatgtct ataagggaac gcgatttgaa
     2161 cgtgaagctt ttgcgagttt tccagatgat ctcttggttc agcgttttac taaggaaggg
     2221 gcggaaactc tagattttac tatagaacta tccttgacct gtgatttggc ttctgatgga
     2281 aagtatgagc aggaaaaatc tgattacaag gagtgtaagt tggatattac tgattctcat
     2341 atcttgatga agggaagagt taaggataat gatctgcggt ttgctagtta tctagcttgg
     2401 gaaacggatg gagatattag agtttggtca gatagggttc agatatcagg agccagttat
     2461 gccaatctct tcttggccgc taagacggat tttgcccaaa atcctgctag caattatcgc
     2521 aagaaactag atttagagca acaggtgata gacttggtgg acacagctaa agaaaagggc
     2581 tatacccaat tgaaatcaag gcatatcgag gactaccaag ccttattcca gcgtgttcaa
     2641 ttggatttgg aagctaatgt tgacgcattc actacagatg atttgttaaa aaattataag
     2701 ccacaagaag ggcaggcttt ggaggagctg ttcttccagt atggacggta tttattgatt
     2761 agttcgtcca gagactgccc agatgctcta ccagctaacc tacagggagt ctggaatgcg
     2821 gtcgacaatc ctccttggaa ttcggactat cacttaaatg tcaatctgca gatgaattat
     2881 tggccagcct atgttaccaa tctcctagag gcggtctttc cggtcatcaa ctatgtagat
     2941 gatttgcgtg tctatggtcg tctagcggct gtaaagtatg caggaatcgt ctctcaaaaa
     3001 ggtgaggaaa atggttggtt ggttcatact caagcgactc cctttggttg gacggcacct
     3061 ggttgggatt actattgggg ttggtcacca gctgccaatg cgtggatgat gtaaaccgtt
     3121 tatgaagcct attcatttta tagggaccaa gactatctca gggagaaaat ttatcccatg
     3181 ttgagggaaa cggttcgttt ttggaatgcc tttttacata aggatcagca ggcgcagcgt
     3241 tgggtgtctt ctccgtctta ttccccagaa catgggccga tttcgattgg caatacttat
     3301 gaccaatctc tgatttggca gttatttcat gattttattc aggctgctca ggaattggga
     3361 ctggatgagg acttgttgac tgaggttaag gagaagtctg atttactaaa tcctttgcaa
     3421 atcactcaat ctggtcgaat cagggagtgg tatgaggagg aagagcagta ttttcaaaat
     3481 gagaaagtgg aggcccagca tcggcacgct tcccatctag tgggactcta tcctggcaat
     3541 ctctttagct acaagggaca agagtatatt gaagcggcac gtgctagcct caatgatcgt
     3601 ggagatggcg gcacaggctg gtccaaggct aataagatca atctctgggc gcgtttggga
     3661 gatggcaatc gagcccataa attattggca gagcagttaa aaacatccac cttgccaaat
     3721 ctttggtgta gccatcctcc ttttcagata gatggtaatt ttggtgctac tagtggcatg
     3781 gcagaaatgt tactccagtc tcatgcagct tatctggtac ctctagctgc cctacctgat
     3841 gcttggtcaa caggttctgt ttcaggctta atggcacgtg gacattttga agtgagcatg
     3901 agctgggaag ataaaaaact cttacagttg accattttat caaggagtgg aggagatttg
     3961 cgagtttctt atccagatat tgagaagagt gtgattaaaa tgaatcaaga aaaaataaaa
     4021 gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag cagaaggtga tcttgttcaa
     4081 ttttattttt aagaagatgt tataaggcag taatttgaaa cttcctttta ataaggattt
     4141 aagaatatag gcagtttcca actagttgaa aaagcgttat aatgataata ggaagtaata
     4201 ctcaatgaaa atcaaagagc acaaactagg aagctagccg caggttgctc aaaacagtgt
     4261 tttgaggttg tagatggaag ctgacgtggt ttgaagagag attttcgagg agtataattt
     4321 gtttgataga gggtgggtct gatggcttat attgagatga aacactgtta caagcgttat
     4381 caggttgggg acacggagat tgtggccaat cgtgatgtga attttgagat tgaaaagggg
     4441 gagctggtta ttatccttgg tgcttcaggt gcaggcaagt caacagttct taaccttctt
     4501 gggggaatgg ataccaatga tgaaggggaa atctggattg atggtgttaa tattgcggat
     4561 tatagttccc accagcgcac caattaccgt agaaatgatg tggggtttgt ttttcagttt
     4621 tataatctag tttctaatct gacagctaag gaaaatgtgg aactggcttc tgaaattgtg
     4681 acagatgcct tgaatcctga tcaggtcttg acagatgtag gtctggctca tcgtctcaat
     4741 aactttccag cccagctttc tggaggggag caacagcgag tctccattgc acgcgcggta
     4801 gccaaaaatc ctaaaattct cctttgtgat gaaccgactg gagccttgga ttatcagacg
     4861 ggcaagcagg ttttgaaaat tctccaagac atgtctcgtc aaaagggagc gacggtgatc
     4921 atcgtgactc ataatggagc tttggcgccc attgctgatc gcgtgattca tatgcacgat
     4981 gccagtgtca aggatgtggt gctcaaccag catcctcagg atattgacag tttggagtac
     5041 tagcatgatc aagcgaaaaa cttattggaa ggacttaatt cagtccttca cagactccaa
     5101 ggggcgtttt ttatccatct tgatcctgat gatgttggga tctctagcct tagtaggcct
     5161 caaagtaacc agtcccaaca tggaggcgac agctaatgct tatttaacaa ctgctcaaac
     5221 cttggatttg gcagtcatgt ctaactatgg cttggatcaa gcagaccaag aagaactaaa
     5281 acagacggag ggcgcagagg tcgagtttgg ctatttgaca gatgtgacta tggataatgg
     5341 gcaggatgcc attcggctgt actccaaacc agagcgaatt tcaacctttc agctaagaaa
     5401 gggacgactt cctcagtcag acagggaaat cgctttggcc actcatttgc aaggccaata
     5461 cagcgtggga caggagatta gttttaaaga aaaagaagag ggtcattcct ctttaaaaga
     5521 ccatacttat accattactg gttttgtgga ttcggctgaa atcctctccc agcgagatat
     5581 gggctacgca ggaagtggaa gtgggactct gacagcctat ggggtgattt tacctagtca
     5641 gtttgatcag aaagtctaca atatagctcg tttgaaatat caagatttag caggtttaaa
     5701 tgccttttca tcagcttatg aagaaaaatc caagcaacat caagaagagc ttgaacaaat
     5761 tttatcagat aatggcaagg tacgtctgca acttttgaaa aaagaaggac aagagtctct
     5821 agacaagggg caagagaccc ttgacaaggc tcagactaat ttgcaggaag gcaagcgtcg
     5881 tttagcagct gctcaagctc gtatacaggc tcaagaaagt caactagcct tgtttcctca
     5941 agttcagaga gagcaggcta gtgctcaact tacccaagcc aagcaggaat tgggcaagga
     6001 agaggacaaa ctaaagcaag ctgaacaaaa tctagcccaa gaaaaggaaa aattagaaaa
     6061 acatcagcaa gtcttggacg atttggcgga gccaaggtat caggtctata atcgtcagac
     6121 catgccaggt ggtcagggct atcttatgta tagcaatgct tcatccagta ttcgagcagt
     6181 gggcaatatc tttcctgtgg tactttatgc cgtagcagcc atggtgacct ttacgaccat
     6241 gactcgcttt gtagacgaag agcgaactca tgcagggatt tttaaggcct tgggttaccg
     6301 tagtaaggat attatcgcca agtttctcct ttatggacta gtagctggga ctgttggaac
     6361 ggctctaggt agtatacttg gtcattattt gctagccagt gtaatttcaa gtgtcattac
     6421 aaaaggcatg gtggtgggag aaacccagat tcagttctat tggacctata gcttactagc
     6481 tcttgtcttg agctggttgg cgagtgtgtt accagcctat ctggtggctt ggagggaact
     6541 tcatgacgaa gcagcccagc ttctacttcc taaacctcct gtcaaaggag ctaaaatctt
     6601 attggagcgt atcggtttta tctggcgtcg tctcagtttt actcataagg taacagcccg
     6661 caacatcttt cgttataagc agagaatgtt gatgacaatc tttggtgtgg caggttctgt
     6721 agctctgctc tttgcaggtt tgggaatcca atcttctgta gcaggagttc cgtctaaaca
     6781 gtttcaacaa atccaacagt atcagatgct tgtctctgaa aatcctagtg cgaccaatca
     6841 ggacaaggta gagctagcag aagtgttgaa agggcaggag atactagcct accagaaaat
     6901 ctattctaaa acgctagaca aggatttcaa aggcaaggct ggtcttcaaa acattactct
     6961 tatgatgata gagaaggaag atttgactcc ctttatccat cttcaacatc atcagcagga
     7021 gctgacatta aaagatggca tcgttattac agctaaactc gcccagctgg caggtgtcaa
     7081 ggttgggcag actttagaaa ttgaaggtaa ggaactaaag gtcgctgcta ttactgagaa
     7141 ctacgttggt cactttattt atatgagtca ggctagctat gagcaacttt acggacagct
     7201 accccaagcc aacacttatc tggtctcatt aagggatacc agtgcaacta gtatcgaaag
     7261 tcaggcgggc ttgcttatga atcaatctgc ggtgtccagc gttgtccaaa atgcttcagc
     7321 cattcgactc ttcgactcta tcgctagctc actcaatcag accatgacca tcttggtcat
     7381 cgtatcggtt ctattagcta ttgtcatcct ttacaatctg accaatatca acgtagctga
     7441 gagaatccgt gaactctcca ctatcaaggt tctcggtttt cataataatg aagtcaccct
     7501 ctacatttac cgtgagacga ttgtgctgtc ccttgtggga atcgtacttg gtctggtagc
     7561 tggtttctat ttacaccaat ttttgattca aatgatttcg cctgcgacta ttctctttta
     7621 tccgcaggta ggctgggaag tctatgtaat cccagtggca acagtaagca tcattttgac
     7681 cttgcttggt ttcttcgtca attattattt gagaaaggtt gatatgttag aagccctgaa
     7741 atctgtagag taaggtagtt atttttagct gattgaactt ctatttacta atattcaaaa
     7801 atcctccgtt tcaaagagca gggaactctt tgtgacagag gattttttct atagggcttt
     7861 agcagctgca attgcggctt cgaagtttgg ctcagaattg atattatcca cgtattcaac
     7921 gtagcgaatc gtattgtcag tatcgaggac aaagactgcg cgtgctaata ggtgccattc
     7981 gttgatcaag agggcataat cgcgcccgaa agaatggtca aagtagtctg aaagcataat
     8041 ggcattgtca aggccttcag caccgcacca acgtttttga gcaaaaggta ggtccattga
     8101 aacagtcaat acgaccgtgt tgtccagtcc agccagttct tcattaaaac gacgtgtttg
     8161 agttgagcag atgcctgtat cgatagaagg aacgacactc aagacttttt tcttgccatc
     8221 aaaatcagcc agagattttt tagaaagatc tgttgtagta agagaaaaat caagcgcctt
     8281 gtcgccgact tgtagttgtt tacctgtaaa gcttacagga tttccgagaa aagttaccat
     8341 aggatactcc aatctttttt cttccattgt atctgaaaca gtcagaattt tccaatgatt
     8401 tgaccggaaa tgtgggcata gaaaaaacgc cagctcacat gagaatgacg tttttcagag
     8461 gcttattttg ccaatccttc agcaatcttg tcaaggttgt atttcatcat gctgtagtag
     8521 ctgtcgcctt ctttaccttg ttctgcgata gaatcagtaa agatttgtgc gtagattggg
     8581 atgtttgtgt cttgagaaac agttttcatt ggacggtcat ccacacttga ttctacaaag
     8641 agtgatggaa cttttgtttg gcgaagtttt tcaaccaagg tcttgatttg ttcaggagtt
     8701 ccctcttctt cagtattgat ttcccagatg taggcacttg gaacaccata ggctttagag
     8761 aagtatttga atgctccttc gctggttaca atgagtttct tttcagcagg gatcttatta
     8821 aatttatcct tactttcttt atcaagtttg tctaacttat cagtatattc tttgagattt
     8881 ttttcataga attctttatt gttagggtct ttggcgctca attgtttggc gatattttta
     8941 gcaaaaataa taccgttttc aaggttaagc caagcgtgtg ggtcttcttt tcctttttca
     9001 ttttgacctt caaggtagat aacatcaacg ccgtcgctga ctgcgaagta gtctttgttt
     9061 tcagttttct tggcattttc taccaatttt gtaaaccaag cattgccacc tgtttcaagg
     9121 ttgataccgt tatagaaaat caaatcagcc tcagaagttt tcttaacgtc ttcaggaagt
     9181 ggttcgtatt cgtgtgggtc ttgcccaatc ggaacgatac tatgaaggtc aattttgtca
     9241 ccagcaatat ttttagtaat atcagcgatg attgagtttg tagcaacaac ttttagtttt
     9301 tgaccagaag ttgtatcttt ttttccgcta gcacatgcta caagaatgat tgcagaaaga
     9361 aagagaacga gtaatgtacc taattttttc attagatcct ccaatttatt agggctttgc
     9421 cccttatttt aacaaatgtt tatttttcag tttcaaatat cgttgtttgg gagcgataaa
     9481 gaagctaatg agaaagaaac tagcagctgt aagcacgata ctagaacctg ccgcaacatt
     9541 aaaactatag ccaataaaga gtcccaaaac tgaagcagta gctccgaagg ttgaggaaag
     9601 gaaaatcata cttttcagac tattagcata cagataagca gttgcagctg gggtaatcag
     9661 catggctaca atcaggatag ttccgacact ttgcatggct gtcacagaca cgagagtcag
     9721 gagtaccatg agaaggtagt gatagaaatt gacaggcatt cccatggctt tagccaagag
     9781 ttcatcaaag gaagttatca agagttgctt gaagaaaatc caaattaaca agaggatggc
     9841 tgcccccaca cccatagtaa taaacatatc cgtatcttgg acggccagaa tattaccaaa
     9901 aaggatatgg aaaaggtcag ttgaactttt agcgacacca atcaagatga taccgagggc
     9961 taagaaagaa gaaaaggtaa tgccgatggc ggtatcgctt ttgataatcg agtttccttt
    10021 gatgtaggta atgatgatgg cagctagcaa tccaaagaca atggctccga taaagaagtc
    10081 aaggcccaag atgaaggaga gggctacacc tggtaagaca gcatgtgaaa tggcatctcc
    10141 catgagtgac atcccgcgta gaataatgaa acatcccaca gctccagcta caatcccgac
    10201 gacaatagct gttatcaagg cattttgtag gaaatggaat ttttgcaatc catcgataaa
    10261 ttctgcaatc ataggtcacc tccattgaaa aagagttgat taccgtaagc ttcttttaga
    10321 ttggtttcgg taaaagtttc ttttgttgga ccaaaggcaa tcacttctcg attgacaagt
    10381 aagacttgat cgaagtagtg gggaatcttg ctgaggtcgt ggtgaacgat gagaaccgtc
    10441 ttcccagctt ttttcaaatc tctcagcgta ttcatgatga tttcctcact gacagagtca
    10501 atcccagcaa agggttcatc caagaggata tagtcggctt cctgcaccaa acatctggca
    10561 atcaagaccc gctggaattg acctccagac agttgactaa tttgacgttc agcgtagtca
    10621 gctaggccga cgatttcaag ggcctcttgc actttcttcc aatgtttagc ctttaaactt
    10681 cgaaagagag gaatagaggg aaatagtcct aacgagacgc attccttgac cttgatggga
    10741 aagttgtagt cgatattgat tttttgttcg acataggcaa ttcggtgtaa ggatttttta
    10801 acttccttgt catcgagaaa tgcctgacct tgatgtggga taattcccag catacctttt
    10861 aatagtgttg atttcccagc gccgtttgga ccaatgatgc cggtaattgt tggtccatgg
    10921 agcactagtg aaatatcctt aagtgccaac gtttctttgt aggagacact gaggttttcg
    10981 atacgtatca taaacttgta ttcctcctgt ctcttaatat acattaaaaa aaaaattaag
    11041 tcaagttaat ttttgaaaaa attaaaataa taactgaaaa atagattcta aagataactt
    11101 tcaggataaa tttctaaatt ataaaacgca tagtatcaag tgtaaaaaac ttggaattat
    11161 gcgttttatc atggaaagat tttttataat agctaaaaaa taatagttaa atggttatta
    11221 attgcattcc ctagtgattt ttgttaagat aaatgcaaat acaaatgaaa gcgagaacaa
    11281 gatgacacgt tatcaagatg atttttatga tgctatcaat ggagaatggc aacagacagc
    11341 tgaaatccca gcagataagt ctcaaacagg aggttttgtt gatttagacc aggaaattga
    11401 agacctgatg ctggcgacaa cagacaagtg gttagcaggt gaagaagtgc ctgaggatgc
    11461 tatcttggaa aactttgtca aataccaccg cctagttcgt gattttgaca agagagaagc
    11521 tgacggtatc acacctgtct taccactcct taaagaattc caagaattgg agacttttgc
    11581 ggattttaca gctaaactag cagagtttga gcttgcagga aaaccaaact tccttccttt
    11641 tggtgtatcg ccagacttta tggatgctag aatcaatgtt ctatgggcta gcgctccaag
    11701 cacaatcttg ccagatacga cctactatgc agaagaacat cctcagcgcg aagagctctt
    11761 gactctttgg aaagaaagca gcgcaaatct cctcaaggct tatgatttct ctgatgaaga
    11821 aattgaagac ttgctagaaa aaagacttga attggaccgc cgagttgcgg cagtggtgct
    11881 ctctaatgaa gaaagttcag aatatgctaa actctatcat ccatattctt acgaagattt
    11941 caagaaattc gcgcctgccc tacctttgga tgacttcttc aaagcagtta ttgggcaatt
    12001 accagacaag gttattgtag acgaggaacg tttctggcaa gcagcagagc aattctacag
    12061 tgaggaagcc tggtctctcc ttaaagcaac cttgattttg agtgttgtca atctttcaac
    12121 cagctattta acagaggata tccgtgtttt gtctggtgcc tacagccgtg ccctttctgg
    12181 agttccagag gcaaaagata aggtcaaagc agcttatcat ctagcacaag aacctttcaa
    12241 gcaagccctg ggtctttggt acgcccgtga gaagttctct ccagaagcca aggcggatgt
    12301 ggagaaaaaa gtggcaacca tgattgatgt ttataaggag cgtctgctta agaatgactg
    12361 gctcactcca gaaacctgta aacaggctat cgtgaagctc aatgtgatca aaccttatat
    12421 tggctatcca gaagaattgc ctgcacgtta caaggataag gtagtgaatg aaactgccag
    12481 tctttttgag aatgctctag cctttgcgcg tgtggaaatc aagcacagtt ggagtaagtg
    12541 gaaccagcct gtagattata aggaatgggg catgcctgct catatggtca atgcctacta
    12601 caatcctcag aagaacctga ttgtctttcc agcggccatt ttacaggcgc ctttctatga
    12661 cttgcatcag tcatcttctg ctaactacgg tggtattggg gcagtgattg cccatgaaat
    12721 ttcccacgcc tttgatacta acggggcttc ctttgacgaa aatggtagcc tcaaggattg
    12781 gtggacagag agcgactatg ctgccttcaa ggagaaaaca caaaaagtca ttgaccaatt
    12841 tgatggacag gattcttatg gagcaaccat taacggtaaa ttgactgtat cagaaaacgt
    12901 ggctgacttg ggaggaatcg cagcagcgct tgaagcagct aagagagaag cagacttctc
    12961 agcagaagag ttcttctaca acttcggtcg catctggcgc atgaaaggtc gaccagaatt
    13021 tatgaaactt ttggctagcg tcgatgtgca cgcaccagcc aaactccgtg tcaatgtgca
    13081 agtaccaaac ttcgacgatt tctttacaac ctatgatgtc aaagaaggag acggaatgtg
    13141 gcgttcacca gaggagcgcg tgattatttg gtaatgcaaa aaatctagtc atcagaaaaa
    13201 aggcatccaa tcatgtgtga aaaccttgat aggatgcctt ttgtaataga aagatttgct
    13261 ggatagttta cttaaatttc gattgtcatc atcttgctag aaaaagggat tgaaggcctt
    13321 ttcgtgagcg atagtagtag ctggaccatg tcctggatag acatcgtagt ttggtagggt
    13381 gaagagttgg gtctggatac tatgaaggag ttgctccatg ctaccagtcg gaaggtcggt
    13441 ccgtccgata gtttcgcgga atagagcatc tcccgtcaag actagatgag catcaggaaa
    13501 gactagggaa acaccaccga tagagtgccc tggggtcggt agaaccttaa aacgaaattc
    13561 ctctagttgg tattcttcgt gaaagacaaa ggtgtgttct gcaggttttg tgaccacatc
    13621 tgccatatca tcgtggcgag ggagaccgga gagattatcg acaggagtgt agagccagct
    13681 ggcttcgctc tctgcgatat agacaggagg attgccaaac gtctcgcgaa ccaagtccag
    13741 actcatgata tggtcataat gggcgtgggt caagagaata gcacagatcg gtttgttgat
    13801 cttctcgatt gtctgacgaa tggcttccca atgactacca ggatcgacga cgatgaggtg
    13861 cttttcgcct tctagataat aggtattttc ataggcaaca ggattcacgg ttttatggat
    13921 tttcatacta gctccaatct caaagaatgt actaatactc ttcgaaaatc tcttcaaacc
    13981 gcgtcaactt tatctgcaac ctcaaagcag tgctttgaac agcctgcggc tagctttcta
    14041 gtttgctctt tgattttcat tgagtataaa ttaagtatag cacagttagg gagaataggt
    14101 aaggatttaa aatgaactta aaaaccagca tgactagatg aagacaggct ggttatcaat
    14161 ttatcaatat tggaaaggtg tcaattgccc ttcataggtt gcataaactc cgtcattagc
    14221 ttgtttgata gacgtgatgt ttagagtgct accgtagttg gcttctcatt tgtcgctata
    14281 ttcactataa gttatcctac tgggcaggtt ctggtcgtta gcatagtatt gaacgactgt
    14341 tttttatagc tttgctggct gaataggaac aggcagcaaa ctcctaacat taggagagca
    14401 aagatagaaa tagcagtttt tttcataggt attctcctta taaactaaag gatagaagaa
    14461 agtatcttga ggatttttat actcttcaaa aatctcttca aaccgcgtca actttatctg
    14521 caacctcaaa gcggtgcttt gagtaacctg cggctagttt cctagtttgc tctttgattt
    14581 tcatttagta ttaattccaa aatccagtca aggtaccagt gtatgtgata cgagttccac
    14641 cgtttatctt tcgtatcttc aatggaattg gggaagtcag aaagtctttg ggttacaata
    14701 tggtttccgt tcttctatct ctccttctat cacctaagtt taaaatctaa cttcgtagta
    14761 tattacggac caataattca gaattatcaa gcaattttga attatttttt tcttattctg
    14821 ttccaatcta gttttcatat tcttaaaaaa gtgataaaat ggtaggaaga attggagagt
    14881 agagatgccg aaagaagtga atttaacagg cgaagaagtt gtcgctttaa ccaaagaata
    14941 tttaacggaa gaggatgttc attttgtcca taaggccttg gtctatgctg ttgaatgcca
    15001 cagtggtcaa tatcgcaaat caggcgagcc ttatatcatt caccctatcc aagtggcagg
    15061 tattttagct aagctaaagc tggatgctgt aacagtagct tgtggattct tgcatgatgt
    15121 ggtggaagat acagatgcga ctttggacga tttggaaaga gagtttggtc ctgatgtgcg
    15181 gatgattgtt gacggagtta ccaagcttgg caaggtcgag tacaaatcga tcgaggagca
    15241 attagcggaa aatcatcgca agatgctcat ggccatgtct gaggacatcc gcgttatttt
    15301 ggtcaaactg tctgaccgct tgcacaatat gcggaccctg aaacatcttc gaaaagacaa
    15361 gcaggagcgt atttccaaag aaaccatgga aatctatgcc ccgcttgccc atcgtttggg
    15421 gatttccagt gtcaaatggg aattagaaga cttgtctttc cgttatctca atccaacgga
    15481 gttttacaag attacccata tgatgaagga aaagcgcagg gagcgtgagg ccttggtgga
    15541 tgaggtagtc acaaaattag aggagtatac gacagaacgt cacttgaaag ggaagattta
    15601 tggtcgtccc aagcatattt actcaatttt ccgcaaaatg caggacaaga gaaaacggtt
    15661 tgaggaaatc tatgatctga ttgctattcg ttgtatttta gatacccaaa gtgatgttta
    15721 tgccatgctt ggttacgtgc atgaattttg gaaaccgatg ccaggtcgct tcaaagacta
    15781 tatcgccaac cgcaaggcca atggttatca gtctatccat acgactgttt atggaccaaa
    15841 agggccgatt gaattccaga ttcgaaccaa ggaaatgcac gaggtggctg agtacggggt
    15901 tgcggctcac tgggcttata agaaaggtat aaaggggcaa gttaacagca aggaatcagc
    15961 tattggaatg aactggatca aggagatgat ggagctccaa gaccaggctg atgatgctaa
    16021 ggaatttgtg gactctgtta aggaaaacta tttggctgag gagatttacg tttttacccc
    16081 agatggagct gtccgttccc ttcccaaaga ttcaggaccg attgattttg cctacgaaat
    16141 ccataccaag gtcggtgaaa aagcaactgg tgccaaggtc aatggccgca tggttccact
    16201 gacaaccaag ttaaagacag gggatcaggt tgaaattatc gccaacccga actcctttgg
    16261 acctagccgt gactggctca atatggtcaa gactagcaag gcgcgcaata agattcgcca
    16321 gttctttaaa aaccaagata aggaattgtc tgtcaacaag ggtcgtgaga tgctgatggc
    16381 tcagttccaa gaaaatggct atgtggcaaa taaatttatg gacaagcgcc acatggatca
    16441 agttctgcaa aagaccagtt acaagacaga agactccctc tttgcggcca ttggttttgg
    16501 ggaaatcggt gcgattaccg tctttaaccg tctgactgaa aaggaacgcc gtgaggaaga
    16561 gcgtgccaag gccaaagctg aggcagagga gcttgtcaaa ggtggcgagg tcaaggttga
    16621 aaataaagaa accctcaagg tcaagcatga ggggggagtg gttattgaag gtgcttctgg
    16681 tctcctagtg cggattgcta agtgttgtaa ccccgtgcct ggtgacgata ttgttggcta
    16741 cattaccaag ggtcgtggtg tggctattca ccgtgtggac tgtatgaacc tgcgtgccca
    16801 agaaaactac gagcaacgtc tccttgatgt ggaatgggaa gaccagtacc ctagctcaaa
    16861 taaggagtat atggcccata tcgatatcta cggtctcaac cgtacaggac tgttgaacga
    16921 tgtactgcaa gttctttcaa atacaaccaa gaatatttca acggtcaatg cccaaccaac
    16981 caaggatatg aagtttgcta atatccatgt gtccttcggt attgccaacc tctctacact
    17041 gaccacggtt gtcgataaaa ttaagagtgt gccagaagtt tactctgtca aacggaccaa
    17101 cggctagttg tcctagctct tactagaaag gctattatga aaatcattat ccaacgggtt
    17161 aaaaaagccc aagtgagtat agaaggccag attcagggaa aaatcaatca gggactttta
    17221 ttgctggttg gtgttggacc agaggaccaa gaggaagatt tggactatgc tgtgagaaaa
    17281 ctggtcaata tgcggatttt ttcagacgca gaaggcaaga tgaacctgtc tgtcaaagat
    17341 attgaaggag aaatcctctc tatttctcag tttaccctct ttgcggatac taagagaggc
    17401 aatcgtccag cctttacagg ggcagctaaa cctgatatgg catcagactt ctatgatgct
    17461 ttcaatcaaa aattagcgca agaagtgccc gttcagacag gcatctttgg agcagatatg
    17521 caggttgagc tggttaataa tggacctgtt accattatcc tagatactaa aaagagataa
    17581 gaaagaccaa gcccagtcgg cttggtcttt ctcatctatc ataaaatact ccaaaaagaa
    17641 atcggttctt gatatgcttg ggggaagtct cttttcaggc tttggcagat gcgataggaa
    17701 gggatgagat gtcctaggat gaggagagtt ccctgaagga aaagtggaat atcacttaaa
    17761 gacaccaagg agagaatcat caggctatcc cataggagaa tttgtaaagc aaaacgccag
    17821 aatctcggtc taatctggga atagagttaa ctaaagtggt cacaaagttg gtttgaaaga
    17881 taggtcaata gcacaggatg aaagaaaatg agccaaccgc tataaatcaa aatccagtcc
    17941 caagtaagcc cccttttaaa tgtcaaaaat gccagcatga ttccatcaat gacaaggagt
    18001 tgaatggttt tgatgaagat gatttttttc atgctaaaac ctccttttcc ttagagacac
    18061 tcccataaag agatgtgttt gtcgtaaaag tctggatagt tttctcttag gtagtcagct
    18121 gtcatataat aaaaagtaga atggcaagca gtgatgattg gcataagaga tgaaaaacgc
    18181 tgagaactaa tgaaggctaa gagaacaaaa aatagaaaat caatggtgag aacccctaaa
    18241 tagtagaagc gaatcttttt attgatttga ggataaatct cagcgaattg atgtttgagt
    18301 cggacgacca agagaaatag caggagtcct tgagcaagga agaaaattaa accagagagc
    18361 aagagccact caaaagatgt ctcgagtcta gtgataaaaa atgcaaatag tagcaaatca
    18421 ataactgcaa ttgctataaa atggattcta tagagttttt tcatgacaag acctccctct
    18481 tttatctaac ttcattctac tccaaaagaa tgggagttac aactaaaatg ataaaaatag
    18541 cagaagggag attctcttaa gttggctagt attctttatt tgagtttcct tctattatct
    18601 aacttcttca tcattccaga caaataaagc tccgattgca ttgaggatat aaaagatgta
    18661 tttaccgata ttggcgaagt ttccttgaat accagctttt gtcagctgaa cgaaattgta
    18721 aatcaaccaa aagccccact gagttgttag ttttaatgca ttcaaagcat tggcaatgag
    18781 ggacagtgca aaggcaatag ttgttacgta ggcaaggaga ttcatcttgc ccccatatcc
    18841 gatatagttg gtcacaaagg caaagaggaa ggcgatgatg gaaatgatga tggccgccaa
    18901 ttttacctgt ttttggctca tttggttggg tctgccttct tgcgaagctt cccacttctt
    18961 tatagcaaag gtataaatga ggaaggtgac gggataggta atgatggccg ccttatttcc
    19021 aaggatataa tcaatagcac cggacaaaat ggtattaaca ataccaaagt aatttcccca
    19081 tttgcttaat ttccccgtga aacgagtgga caacatggaa atcccaacgt tggttacgga
    19141 aatcaatcca aagggtacaa gagctgtcca tgatccccag tctacaaatt tatcgaggtg
    19201 tgagttgagg taaccagatg caatcgcaat cccaacgacc aaagcaaccc cgaagaggtc
    19261 aaactattta gatgtagcaa aaatttttag tgattttttc ataggttaaa ctacctttct
    19321 ttttttcaaa tattctccca ccaaatgaaa gtaaaataaa atgatagaaa taaaaccctg
    19381 aaaataaaac tttcagggtt ggtaggggac ttgagaaatt agttgatttt ctcgacatag
    19441 agttgttttg caatgtccat attcacttgt aaatcctcgt cgttactgag gatagtgaag
    19501 gtattgctga agccatcaaa ctgcttgact tggagctggt caccgatgtg aagtgagtgc
    19561 ttgtccagat aatggagaat gtcaaaacta tcgtgcaccc gagtcaggcg gtaggcgcca
    19621 gcttccttga tatcagctag tgggaggtta ttgatttcaa cgagtagttc tcccttggca
    19681 ggaatagttc ctccgtgggg gcaggtttta gggaaaccta gcagtttatc tagtctttcc
    19741 acgaacaggt cagagacagt gtgttccaag acctcagctt cctcgtgaat ctggtcactt
    19801 gtatagtcta aatgatgaac tagaaaaact tcaatcaagc ggtgcttacg atagagctca
    19861 gagaccagtt tgagaccgag gtcagtcagt agatagccac attccttgtc ctttaggatg
    19921 agattttcac ttttcattcg tttgatcatt tcagttacgg cagggggaga gacttgcatg
    19981 cgagccgcaa tttccttgtt ggtaatctta tgcaggtcta tgccaatttc ataaatacat
    20041 tttagatagt cttctttgtt tggggtcatt cgtttcctct tgtctaatat ctttatctag
    20101 tatatcaaaa aaagctagat ttctctagct gtgacttttt atgttatact tattgcaaga
    20161 gaaaaaacga ggagatggat atgacgaaaa tagctcttct ttcagatatt catggaaata
    20221 ccaccgcctt ggaggctgtt ttggcagatg ctcagcagct aggagtggat gaatactggc
    20281 ttttgggaga tattctcatg ccagggacag gacgtagaag gattttggac ttgttggatc
    20341 aactaccgat tacggctaga gttttgggaa actgggaaga cagtctttgg catggtgtcc
    20401 gtaaggaatt ggacagtact cgccccagtc aacgctatct cttgcgccag tgtcagtatg
    20461 ttttagagga aatttcccta gaagaaattg aagtgctcca caatcaacct cttcaaattc
    20521 atcgtcagtt tggggatttg acggtgggaa ttagccatca tctgcctgat aagaactggg
    20581 ggcgagagtt gattcatact ggcaaacaag aggagtttga ccgcttggtg actcatcctc
    20641 cctgtgatat tgctgtttat ggacatattc accagcagtt gcttcgttac gggactggtg
    20701 ggcaattgat tgtcaatccg ggttcgattg gccaaccttt ctttttggac gctcagctac
    20761 ggaaggactt gcgggcccag tatatgattt tggagtttga tgacaaaggc ctggtagata
    20821 tggacttccg acgggtagac tacgatgtgg cagcggaatt gcagctggct aaagacctga
    20881 gacttcccta ttttgaggtt tactatgaaa gtctggtcaa tgggatccac catactcatc
    20941 atcaggaatt tttgagagaa ttggctcaga aagagggctg cgaccgggag ttagacgact
    21001 ggttgaaaag tggtaacgat tgacattaca actaaaaagg gtataataat agaaaaagaa
    21061 gagtagaggc agggtagcct cgtaaaaagg agaagaggat gcaaattcca agtagattta
    21121 ccattgcgac tcatatgctg ataatcattg ccctcgaggg gaaggaaagc aaggtgacca
    21181 gtgattttct ggctgctagt gtcggggtca atcctgtcat tatcagaaag atcttgtccc
    21241 agttgaagaa ggcagagctg atttcagtag cgcgtggaac gggcggaaca gagattgtca
    21301 aggaccttaa ggatattagt cttttagatg tttatcaggc ggtcgaatgt cttggtaaga
    21361 caggtcaact cttcagtttc catgacaatc cgaatccaaa ttgccctgta ggagctcata
    21421 ttcatgatgt tttggatcaa aaattggaga gaattcagtt gactatggag gcagaacttg
    21481 gtcaaaccag tctagaaaaa gtcgtggccg atgcagagag tcagatgaag gattaagagg
    21541 gataaatgcc ctcttttttc tttggataat tatgataaaa tgtagctatt aaaggagtaa
    21601 gaaatgtatc tcgttatagg aattgtatta gcctttatag tgtcattttg gaaggataat
    21661 agaagtttgt ggaatccagt attattttta ttatccctca tttcaagtta tttttatcta
    21721 tcctaccttt tttataaaaa tggatacgag aatgttcagt tagcttttta tgtatttgcc
    21781 tttgtcttac ttcctttttt gctttttcta agtggcatct ttttaatcta taatggggtc
    21841 attttgttga agcgagaggg acgttccaag ccccattatc tctcaatgct atttgatttt
    21901 tattgactat tagattctat ttaaaaagac ttagaatgca catgaaagta tgtattctag
    21961 gtcttttgtt ttgtatacat ttaattttca agagtattat ctatttttcc atgcctggta
    22021 acgagtatca atcaataact gggtaaggcg acccaaggtt tctctttctt ctggagtgag
    22081 ggattgagct tggacaaaga gatgatgaat gtattcaagc gcctttaagg aagccaagtc
    22141 attgatagag ctaataccag cctcaagaat agtgccaaag aagaggtcga agtagagctg
    22201 aagttcttcg tcagggactg tggccaccca ttctttaaag gttgtgtcta cttgctggct
    22261 atcactgttg gtcttatcca gttggacgaa gtgcttatcc tcaatctgcc aactaaaggt
    22321 atcgtgctgg gcgatgccac ccagggcagt actctgaacg atgatttggt gagcaggaat
    22381 ttccagcatc ataccgataa tggaaccttg tggaatgaat atcttgcttc tatccattat
    22441 cctttgataa cccgcagtct gtgtcaattc ttgatggaga ccaggtgcat caaatgtata
    22501 aactgctgtg atctgatttt gcaaactttg ctcaatttgg ctagcagcat agatagcgag
    22561 atttcctccc ttggaatgcc cagctagaat aaccttttgc ttaggatgat gggcaaaaaa
    22621 gttctttaaa tagcgaaggg cgtgcttttg agcaggaatt tccttcatat aggtcaggtg
    22681 gaaatcttcc ttccagccaa tgatactgtc atctgtccca cgaaagacaa tcagataggt
    22741 atcgaggctg acacgataag tcatagccgc aaattgcttt tgcagttcag ggtcgatgtc
    22801 gttgataaaa tgggagagtt tgcaattttt gaagcgcttg tgttgagcca attcatctaa
    22861 taattgaagg cgatttttgc tagtaagcat ggtgggatct cttggaacct gaggtgctag
    22921 atctaaaaga cgttgaggaa gtgtggagac cagattatca aaggagaggt aggtgatttc
    22981 tattaaggtt agaatgtcta actcattcaa gggaaggtcg taataagaat catatgcgac
    23041 atctttcaga tagtcaaaaa tattggccat aagagctcct ttctttttat ttatcttagc
    23101 aaatttccct caaattagct agtagcattg cctgtttgta ctggctaaaa acaggctatt
    23161 tcaaattcag tttcagacca tctggcatgg aaaaatctgt tataataata gaaaaggaga
    23221 agcgcatgca caagatttta ttaatagaag atgatcaggt cattcgtcaa caggtcggga
    23281 aaatgctctc tgaatgggga tttgaagtgg tcctggtaga agactttatg aaagttttga
    23341 gtctatttgt tcagtcggaa cctcatctgg tcctcatgga tattggtttg cccttgttta
    23401 atggttatca ctggtgtcag gaaatccgca agatttccaa ggtacctatc atgtttcttt
    23461 cttcgagaga ccaggctatg gatattgtca tggcaatcaa tatgggggcg gatgactttg
    23521 tgaccaagcc ttttgaccag caggttcttt tagctaaggt tcagggcttg ttgcgtcgtt
    23581 cctatgagtt tgggcgtgat gagagtttgc tggaatatgc tggtgttatc ctcaatacca
    23641 aatccatgga tttacattat caagggcaag tcttgaattt gaccaagaat gaattccaga
    23701 ttttacgcgt gttatttgag catgcaggca acatcgtagc acgtgacgac ctgatgcggg
    23761 aactttggaa cagtgacttt ttcattgatg ataataccct ctctgtcaat gtggctcgtt
    23821 tgcgtaaaaa gttggaggag cagggattgg taggatttat cgagaccaag aaaggaatag
    23881 ggtacggatt gaagcatgct tgattggaaa caattttttc tagcctatct gcgctcccgt
    23941 agtcgtcttt ttatctatct gctttctttg gcatttcttg tcttactctt tcagttttta
    24001 tttgccagtc taggaattta cttcctctac tttttcttct tgtgttgctt tgtaaccata
    24061 ttatttttca cttgggacat attggtggaa acgcaggtct atcgccagga acttctctat
    24121 ggagagaggg aagccaagtc tcctttggaa atagctttag cagaaaaatt agaagcgcgt
    24181 gagatggaac tctatcagca gaggtcaaaa gcagaaagaa aactgacgga tttgctggat
    24241 tactatacct tgtgggtcca tcagataaag acccccattg cagccagtca actcttagtt
    24301 gcagaagtgg tcgaccgcca actgaagcag cagctagaac aggaaatttt caaaatcgac
    24361 tcctatacca acctagtttt acagtacctg cgtttagaaa gtttccatga tgatttgctc
    24421 ttaaagcagg ttcaaattga ggacttggtc aaggaaataa ttcgtaaata tgctcttttc
    24481 tttattcaaa aaggcttaaa tgtcaatcta catgaccttg ataaagaaat cgtgacggat
    24541 aaaaagtggc tgctagtggt tattgagcaa atcatctcaa acagtctcaa gtacaccaag
    24601 gaaggtggtc tggagattta tatggatgac caagagcttt gtatcaaaga tacgggaatc
    24661 gggataaaaa acagtgatgt cctccgagta tttgaacgtg gcttttcagg atacaatggc
    24721 cgtttgaccc agcagtcctc tggacttggc ctttatctat ctaagaaaat ttctgaagaa
    24781 ctggggcacc agattcgtat cgagtctgag gtcggaaaag gaacgacagt gcggattcag
    24841 tttgctcaag tgaacttagt ccttgagtaa aaatagatga gaaaaagcct ccagattgga
    24901 ggcttttatg ctagactctt atttctcaac gcgtgatttg ttggcgatat cagctaggat
    24961 agcttgaaca aaattatcaa ctgagacagt ttgtgtttct ttttggccgt agcgacgaac
    25021 gttgactgtt tcgtcttcca tttctttgtc tccaacaatt aattggtaag gaatcttgct
    25081 ggtttgtgaa gcacggatct tgaactgcat tttttcattg cgctcatcta cgtctgcacg
    25141 gacaccgcgg tcacggagtt tcttggccac ttcccaagcg tagtccacgt gtttttcgtt
    25201 agatactggg atgagggtta cttggtgtgg tgccagccat gttgggaagg cccccttgta
    25261 gttctcaatc aagatagctg tgaagcgttc catagttgag ataactccac ggtggatcat
    25321 gactggacgg tgatcttcgc catcagctcc gatgtatttg aggtcgaagc gttctggtaa
    25381 caaaaaatca agttggatag tagaaagggt ttcttctttt ccaagggcag ttttaatctg
    25441 gatatccaat tttggtccgt agaaggctgc ttcaccttcg gcttcaaagt agtccacgcc
    25501 catttcatca agagctgcac gaagcatggt ttgggcattt tcccacatct catcgttatc
    25561 aaagtactta tgagtatctt gagggtcacg aagagagagg cggaagcggt agtcagtcaa
    25621 gttgaagtct tcataaacat cgataatcaa ctgaagggca cgttggaatt cttcttggat
    25681 ttgttctgga gtaacgaata ggtgaccgtc gttgagtgac atttcacgta cacgttgaag
    25741 gccagtgagg gcaccagatt tttcgtaacg gtgcatcata ccgatttcag cgatacggat
    25801 tggcaattca cggtaagagt gaacatggtg tttaaaaact tggatgtggt gcggacagtt
    25861 cattggacga aggacaaatt cttccccgtc acccatgtcc atggttggga acatgtcttc
    25921 ttggtaatga tcccagtgac cagaagtctt gtaaagctca acagaagcaa gtggtggagt
    25981 gtagacgtgt tggtagccag aagccaactc tttgtttacg atgtagcgtt ccaattcacg
    26041 acggatagtc gcaccatttg gcaaccagaa tggcaaacct tgtcccactt cttgtgaaat
    26101 cataaagagg tcaagctctt taccaagttt acggtggtca cgttccttag cttcttcacg
    26161 catttgaagg tagtttttca agtctttctt gtcaaaccaa gctgtaccgt agatacgttg
    26221 catcatagcg ttgtcgctgt ttccacgcca gtacgcacca gctacatgga gaaggtggaa
    26281 gatttggata cgacctgttg atggaacgtg aggtccacgg cagaggtcta catattcacc
    26341 ctgacgatag atagtcaaac cgccttcgtc ttctgagtgt tcttcaatca attccaactt
    26401 gtaagggtca tttttgaaga tttcacgtgc ctcgtcttta gtcacttctt cacgaataga
    26461 tgggaagttt tctttgacga ttttttgcat ttcttcttcg atacgaggaa ggtcttcgtt
    26521 agagatttga ccagctgtgt tgtcagtatc gtagtagaaa ccatcttcga tggctggacc
    26581 aactcccaag tgaatgtctg ggaaaagacg acgagctgct tgggcgaaca agtgagctgc
    26641 tgagtgacgc aagattggaa gggcatcttc gtgatcaggt gtcacaattt cgatgcttcc
    26701 atcttcagtg atagcgcgag tagtgtcgat gagtttgccg ttgaatttac cagccaaggc
    26761 ttttttagct agggaattgc tgatagattg ggcaatttca aaagttgtta cgccagattc
    26821 gaattcacga acagcgccat ctgggaaagt aatgttaatc atgatgttct ccttttttat
    26881 tatttcatag tttctaagca ttgatttttt atcagcagac tacttccaag tcctaacgtt
    26941 caattgcttt tctttatcag agaggaagtt ttccatttcc gtcagaatgt ctatatccaa
    27001 acgttgagaa agttctaata gccaccagat attttctgaa agtttttgtt ccagtgtgta
    27061 gggtgtttca tcatagtagc gtccttgctt tgtcatcacc agtcgttgga aatttccaat
    27121 atcattagat aaagccaaga ggtcttcttc taccgtccac ttggaatcat gatgcttaac
    27181 ttccagttcg tgataagttt gtcggattgc ccaactgcgc tccactaatt cttgcaactc
    27241 cataattagt atcctaataa aaaaatgcga catcctcgaa aggacgtcgc aacgtggttc
    27301 caccttcatt tatgtacctc aaaagagagg gacacctctg atcggctcta acgtggccac
    27361 cgttttatgt tttcataaaa aactcaagag tagtatcagt ttagacttcc tatgcgtttc
    27421 cagcaaccac gcactctcta gtagaaaggg actaagtgac ttgtctctat ggattattat
    27481 agcatgattg tgagattttt caaggatttt gtgaaagttt tttgtttttc attttttgta
    27541 gaatatgctt gatgctaata ccagaatcca tgcccaccag agcaactgtt tcatagatta
    27601 gcaagtaaat tagtataaac tcaccaaagg ttatgatagt aaagtaaaag agcagtccgt
    27661 taccaactaa ccatcaaagt gagaaacgga aacggtagct atagagtaac gatataatca
    27721 agattaccag aggtgtaaag aagagaagat tgtttatata gagttccttg agtgtaaggg
    27781 ggtcagaaac aactagtaag aacaactcat aaagtggcca ataaaagaat aatatgacca
    27841 gatagtaggg gagatgggaa tagaatctac gcatgataat cacctcgttt taaaaaaaca
    27901 gacaacttag atctcttgct atgattatta tagcatgttt aaaacaagaa agtaaatttg
    27961 ttgacaaaga agatttttct tttcactaga atcatagtta gttttcttgg tagaaatatt
    28021 ttgataataa ttaagcaaga ctattgacat tgattattaa gagtgtcaca attattgtaa
    28081 ctaaaataat tacaacaaga gaggtataaa aaatgaaact agcagttatt gcagcaaatg
    28141 gacaagcggg gaaagcaatt gttgaagaag cagtcaaacg aggacatgaa gtaacggcta
    28201 ttgttcgttc tgaaaacaaa agtcaagctg agtctattat taaaaaagat ttatttgagt
    28261 tgacaaaaga tgatcttact ggatttgatg ctgttatttc agcgtttggt gcttatacac
    28321 cagatacgct accgctccac agcaaatcaa tcgaactatt taatcagctt cttgctggaa
    28381 cacagacacg ttttctagtt gtagggggag caggaagtct ttatatagat gaaacaaaaa
    28441 cgacacgact tttagatacg tctgattttc ctgaagaatt taagtcacta gcaaaagatc
    28501 aagcggatga attggatctt cttcgtacaa aaaataatct caactggact tttgtcagtc
    28561 ctgctgtaga ttttattccc gatggtgaaa aaacaggaaa ctacattcta gcaggagaaa
    28621 tttttactac taatgaaaaa ggaataagcc agattagtta tgcagattat gctattggat
    28681 tggtagatga acttgaaaaa ggtcatcata taaaagaacg tatctcttta cttgaaaaat
    28741 aataactatg agagtattaa tgtttgacag aaaatttaaa tcttgataaa atagggattg
    28801 tcgtaaagac aaataacttc ttcttggtta caggcatgcc aacctgtcac tcggatgaag
    28861 ccaaataaaa aggagaaaca tcatggcaat ctcaaaagag aaaaaaaatg aaatcattgc
    28921 acaatatgca cgtcacgaag gtgatacagg ttcagtagag gttcaagttg ctgtccttac
    28981 ttgggaaatc aaccacctta acgaacacat caaacaacac aaaaaagacc acgctactta
    29041 ccgtggattg atgaaaaaaa tcggtcgccg tcgtaacttg cttgcatact tgcgtaaaaa
    29101 cgacgttaac cgttaccgtg aattgatcaa ctctctagga cttcgtcgct aattcaagat
    29161 acaaaggccg tcaaaagcac aaagcaaaaa taggaaaatt gacgaagaaa cttcagtttc
    29221 taggagattt tatctttttt gccaagtgct taggccgtgt tcaattgagc atatcttgat
    29281 aataaagcta ctctaaattg ggtagctttt ttgcgttgtc accttacctc gctatactca
    29341 agtataatct tcggttacgg ttcctagcac tgtaaggtaa aataaactag cttttctccc
    29401 ttcggggaga ttttttttgt ttcactgaaa gtttcgtacg atcttcgcct cgtcgcctag
    29461 tctataaacg atttatctag caagaatcat gatgctaagg gcgtcaaaaa tccgtatgaa
    29521 aatagggaaa tgacacagtg ttcgatgagc acaaggagtt tcatcttttt cactaggatt
    29581 ttagcccggg ctaaaatcag ctctctgact tcagagggct tttttattga ggttttatcg
    29641 gtaacaattt tggagactac aaaaacctca aatggtatca gctaattaca ccataaaggt
    29701 gcgcagttac tcggcttttc aagccgagta gctgtatgca agccccctag aagagcccac
    29761 tctttacaaa gtaaagtata gtatgttata ctttacatgg aagtagtcac tgaattccag
    29821 ttagaaatta ctttgtaact acgttttgag gaggagtaaa atgctttcct acgttcgaca
    29881 ttacccacta gcgatagcta aattaatgtg tctgtgctct cctgaaatct gctgatttat
    29941 tactgactaa tacaggaggt ttttttatgg gacagacaat catatctgct attggtgttt
    30001 atatttccac cagtatcgat tatttaatta ttttaattat tttatttgca cagctatcac
    30061 agaataaaca gaaatggcat atttatgcgg ggcaatatct aggcacaggc ttacttgtag
    30121 gggcgagttt agttgctgct tatgtcgtta atttcgtgcc tgaagaatgg atggttggat
    30181 tgcttggttt aatccctatc tatttaggga ttcgctttgc aattgttgga gaagatgcgg
    30241 aagaagaaga ggaagaaatt attgaaagat tagaacaaag caaggcaaat caactgtttt
    30301 ggacagttac attgctgaca attgcgtctg gcggagataa tttaggtatc tatatacctt
    30361 attttgcttc gttagattgg tcacagaccc tcgtggcctt gcttgtgttt gtaatcggca
    30421 taattatctt ttgcgagatt agtcgggtgt tatcctctat tccgttaata ttcgagacaa
    30481 ttgaaaaata cgagcgaatc attgtgccct tagtattcat tctacttgga ctatacatca
    30541 tgtatgaaaa tggcacgata gagacttttc tgatcgtgta gatttttttg tttcactagg
    30601 attttagccc gagctcaaat cagctctctg attttcagag ggctttttca ttgagtataa
    30661 atggacaatc ttaaagttac tctattgtag agtggctttt gatttgatta ggagattctt
    30721 ataaatatag taaaatgaaa caaaaacagg acaaatcgat caggacagtc aaatcgattt
    30781 ctaaaaatgt tttaagaagt agaggtgtac tattctagtt tcaatttgat atataaatga
    30841 aaaccttagc tgtttggcca aggttcattt cttctatgca agttcttctc ttttcttatc
    30901 tgggttccag atgaagcttg cgataaagct aaagatgatg gttaggatag cgaggataat
    30961 agcaaggatg agggcaggga tgcggataaa ccaccagagt ggatttggtt ttttatcatt
    31021 gtgccattgt ttcgtttctt cgtccagacg ttggaattct gtttgaatac gattggcgac
    31081 tgtttcaatg ccttcatcat tcattttctt gatatctgag atatcgattg gatttccaaa
    31141 gttcatatcg acacgttcac ggctaatcaa gcccttcaaa gtcatgggac cggtgtaggt
    31201 aaccggcatg atacggacct tggccatttt ggcaatcagt gctgcgcccc ccttgacatc
    31261 gtttgagtgg cggctaccac ttggaaacat gatgagagag cggtcacttt ttttgagaac
    31321 gttgatagga tatttgatgg ctgaggcgct gggattttca cggtcgatgg gaaaggcgcc
    31381 acacatacga atccaccaac caaagatacg gttggtaaag agttcttttt ttgccataaa
    31441 gatgaactgt tttggcttgg tcgcaaaggc catataaaca ggatcccacc aggtacggtg
    31501 aggcgcaact aaaatataat tttcatcttg attaggaatt ttatcagtat tatgatagtg
    31561 agcattgcca ttgatggacc ataagagcaa tacaactaat ccacgcaaat aagtataaaa
    31621 catgcgatct ccttcgattg ttttcttgtt attattatac cttatcaaag gagggctggc
    31681 aaacttttcc cttgactaga tacatattta ggatgaaatt agaattctgt taaaaaaaat
    31741 gatataatag aatttatgga taaaaataag attatgggat taacccaaag agaagtcaag
    31801 gaaagacagg ctgagggttt ggtcaatgac tttaccgcat cagccagtac cagcacttgg
    31861 caaatcgtta aacgaaatgt ctttaccctt tttaacgctt tgaacttagc cattgctttg
    31921 gctcttgcct ttgtgcaggc ttggagcaat ctggtcttct ttgctgttat ctgctttaac
    31981 gctttttctg ggattgtgac cgagctacga gccaaacaca tggtggacaa gctcaatctc
    32041 atgaccaagg aaaaggtcaa aaccatccgt gatggtcagg aagttgctct taatcctgaa
    32101 gaattagtgc taggagatgt cattcgtttg tctgcaggag agcagattcc tagtgatgcc
    32161 ttggttttgg aaggctttgc ggaagtcaat gaagccatgt taacgggaga aagtgatttg
    32221 gtgcaaaagg aagttgacgg cttacttttg tcaggaagtt tcctagccag tgggtcagtt
    32281 ttatctcaag ttcaccatgt cggtgcagac aactatgctg ccaaactcat gcttgaggct
    32341 aagaccgtta aacccatcaa ctcccgtatc atgaaatcgc tggacaagtt ggctggtttt
    32401 actgggaaga ttatcattcc ctttggtctg gctctcttgc tggaagcctt gcttttaaaa
    32461 ggcctgcctc tcaagtcatc tgttgtaaac tcgtcgacag ctcttttggg aatgttgcct
    32521 aagggaattg cccttttgac cattacttcg ctcttgactg cagttatcaa gctaggtttg
    32581 aaaaaggtct tggtgcagga gatgtactct gttgagacct tggcgcgcgt ggatatgctc
    32641 tgtctggaca agacgggtac catcacccaa ggaaagatgc aggtggaggc tgttcttccg
    32701 ttgacggaaa cgtatggtga agaggctatt gccagcatct tgactagcta catggcccat
    32761 agtgaggata agaatccaac tgcccaagcc attcgccagc gttttgtggg agatgttgct
    32821 tatcctatga tttccaatct tcccttctcc agcgaccgca agtggggggc tatggagtta
    32881 gaaggcttgg ggacagtttt cttaggggca cctgagatgt tgctggattc tgaagtccca
    32941 gaagccaggg aggccttgga gagaggatca cgtgtcttgg tcttagctct cagtcaggag
    33001 aaattagacc atcacaaacc acagaaacca tctgatattc aggctctagc cttgctggaa
    33061 atcttggacc ccattcgaga gggagcagca gagacgctgg actatctccg ttctcaggag
    33121 gtaggactca agattatctc tggtgacaat ccagttacgg tgtctagcat tgcccagaag
    33181 gctggttttg cggactatca cagctatgta gattgctcaa aaatcaccga tgaggaattg
    33241 atggccatgg cggaggagac agctattttc ggacgtgttt cccctcatca aaagaaactc
    33301 atcatccaaa cgttgaaaaa agcgggtcat acaacggcta tgacagggga cggggttaat
    33361 gatatcttgg cccttcgtga ggcggattgt tctatcgtga tggcggaggg ggatccagca
    33421 acccgtcaga ttgccaatct ggttctcttg aactcagact ttaatgatgt tcctgagatt
    33481 ctcttcgagg gtcgtcgcgt ggtcaataac attgcccaca tcgccccgat tttcttgata
    33541 aagaccatct attccttcct gttagcagtc atctgtattg ccagtgcttt actaggtcgg
    33601 tcagagtgga ttttgatttt ccccttcatt ccgatccaga ttaccatgat tgaccagttt
    33661 gtggaaggtt tcccaccatt cgttctgact tttgagcgaa atatcaaacc tgttgagcag
    33721 aatttcctca gaaaatccat gcttcgtgcc ctaccaagcg ctctcatggt cgtcttcagc
    33781 gtcctgtttg tgaaaatgtt tggcgcgagt caaggttggt ctgagttaga aatctcaact
    33841 ctactctatt atctcttggg gtcaattggt ttcttatccg tatttagagc ctgcatgcca
    33901 tttaccctat ggcgtgtcct cttgattgtt tggtcagtag gaggtttcct agccacagct
    33961 ctcttcccaa gaattcaaaa actgcttgaa atttcaacct taacagaaca aacgttgcct
    34021 gtttatggtg tcatgatgtt ggtctttacc gtgattttca tcctgaccag tcgttaccaa
    34081 gcgaaaaaat aaagaaagac tgcaatctgt ggattgcagt tttttatacg atggatctat
    34141 cgtagatctg atgtgcaagg cctacgtgcc gatcatctat cggtgaaccc aagagcgacc
    34201 ctcaagcctg cttggattga ggtaatagat tcaaatatct gtagttagac tatttgaagt
    34261 ttgatgtaag aaagagaaag cgacagattg aagtaatttt aactctcttc tattgctaga
    34321 acaaatggtc ggataggttg gtagtttgaa aatgaagatg ctatctattg ttaaatggaa
    34381 catagtgtta tttattagaa aatcgtttgg tttatttctt atcaaatacg aaaagcaact
    34441 taaatatttc aactaaaata gatgttatga agaaaaggta aaatgatttt ggcatagtga
    34501 ggttctgttc tatttgatat catatttttg ataaaaacaa aaatgtccat tgcaaaggac
    34561 aaaatgcgaa gtatattatt ttttgaaagc gatataatgg attcataaag gaggtgtatc
    34621 gtgtctagaa aacaagaaca aatggaaacg ttgttgctcc ttttgcgaga tagtaaggat
    34681 tatatatctg ctaaagtatt gggagaaaaa ttaaattgct ctgataaaac ggtttatcgc
    34741 cttgtcaagg gaatcaacaa agattgtccg gtagaagcat tcattttatc tgaaaaaggc
    34801 agaggtttca aattaaatcc aagaagttcc ctcgtggacg ttgatgggaa ttttacagag
    34861 gcttttgatc ctgaagtaag gcgtgaaaaa ttactagaac gtctcttgtt gactgctcct
    34921 aagccacatt ctatttatga tttaggagag gaattctacg taagcgagtc agtagtacta
    34981 aaagatcgtc agatattaca agagagtcta gcaatttatg ggttagattt aaaaatgaga
    35041 caacgaaagc tttttattga tggggatgag gctcaaattc gttcagccat tctaaatcta
    35101 ctgccaatgt ttaatcagtt ggatttagag caaattacac agaataaggt tcagcctctt
    35161 gacggagaac ttgctcactt ttgtttggga ttactgatta cacttgagag agaattgggg
    35221 gtaaacattc cctatccata taatataaat attttctctc acctgtatat ttttatcagt
    35281 aggaatcgtc gtagtactag tattcatgtt gtagcacctt caaaacctac tattgttgat
    35341 gagaaaattt acagtgtctg tcaaaaaatt attcaagaaa ttgaacaata ttttaggatg
    35401 aaggttgatg cagttgagat tgactatctt tatcaatacg ttgtatcttc gagattgcaa
    35461 aaaccatttt cttccgggaa gcttcctttt tctcagcgag ttttagatgt cactcattac
    35521 tattttagcc gtatgtgtat ggacaataga gagattgaaa cgacagatcc tgactttgtt
    35581 gacttggcga gtcatatcag tcccttactg aggagattag ataatagagt acagattaag
    35641 aatagtcttt tatcacaaat tcttttaacc tatcctaatc tggttaaaga gttaacaact
    35701 atttctaaag aagtgagtct agtatttggt tttgcttcct tgagtctgga cgagattggt
    35761 tttctagtct tatattttgc acggtttcaa gaaaagcgag cacgtcctct aaaaacagta
    35821 gtgatgtgta catcaggtgt tggaacttca gagcttttac gagcacgatt agaaaagcaa
    35881 ttttctgaat tggatattat tgatgtagtt gcttatcatc aattagatga gctgataaat
    35941 ctatatccag atttagattt cattgtgacg acggtagctt tgcaggaacc agcaagtgtc
    36001 ccgtttgtcc tagttagtgt ttttctaacc gagggtgata aacaacgtct tcaagcaaaa
    36061 attcaggaga taaactatga ataatctttc gcttgtcctt atggatatat ctgttcaaaa
    36121 tcgtcaagaa gcctacaaag aattagcaaa tcaaatcagc cttcttgttt ctgaagatac
    36181 agaaaaaata gaagagcttc tatattaccg tgagagacag ggaagtatag aggttgctaa
    36241 aggtgttctt ctaccacatt gtgaaggaaa ctttcaacat catgtcttag tgattactag
    36301 attaaaatca cctatcagag aatggtcgaa ggatatccag tgtgttgacc ttattatcgg
    36361 tttggccatt gcagtatcac aggacaagtc atgtattaaa acattgatga gaagactagc
    36421 agatgaatca ttcataaatc aattaaaaca gttaacaaaa gaagaattac gggagataat
    36481 atatggaaat caaagatatt cttaatgtga gtctgatcca gacggattta cagatgcaga
    36541 gcaaagaaga ggtttttgag gcattagctc aactattggt tgagacgggt tatgtgtctg
    36601 atagagacca atttatcgaa ggtctttatc agagagaggc agaaggacag accggtattg
    36661 ggaattatat tgctattccc catagcaaga gttctgctgt ggagaaggcg ggggtagtca
    36721 tagctataaa tcacaatgag attccttggg agaccattga tgggaaaggg gtcaaagtaa
    36781 ttgtactctt tgcagttggt gatgatacag aagctgctag ggagcatttg aagaccttat
    36841 cactctttgc tcgaaaactt ggtaatgacg aagttgttgc caaattagtt cgggctcaga
    36901 catctgatga tgtgattgca gctttttgtt aataagaaaa aattttggag ggtatccgta
    36961 tgaaaattgt tggtgttgca gcttgtactg tgggaattgc ccacacttat attgcacagg
    37021 aaaaattaga gaatgccgca aaggtagctg gacatgtgat tcatgttgag actcagggga
    37081 caataggggt agaaaatgaa ttgagtcaag agcagattga tgcagcggat gtagttattt
    37141 tagcagttga tgttaagatt tctggtatgg aacgctttga gggtaaaaag attatcaagg
    37201 ttccaacaga agtggcagtc aaatctccca ataaactgat tgctaaagct gttgagattg
    37261 ttacgaaata actgaaaata tttaaggaga aaatatatgt tgaaacactt aaacttaaaa
    37321 ggtcacttat tgacagccat ttcctatatg attccaattg tttgtggtgc aggattctta
    37381 gttgccattg gtttagcaat ggggggtggt gttcctgacg ctcttgtagc aggaaaattc
    37441 actatctggg atgctttagc aactatgggt ggtaaagccc ttggtctctt gccagttgtt
    37501 attgctacag gtttgtctta ctcgattgct ggtaagccag ggattgcacc aggttttgtt
    37561 gttggtctaa ttgccaattc tgttggttca gggtttatcg gtggtatctt gggaggttat
    37621 atagctggtt tcttggttca agcgattatt aaaaaggtca aagtaccaaa ctggattaaa
    37681 ggtttaatgc caaccttgat tattcctttt gtagcctctt tggtaagtag tttgattatg
    37741 atttatatta ttggagcgcc tatcgcagcc tttaccaact ggttgacgag cttattacaa
    37801 agcttgggaa gtgcttcaaa tggtttgatg ggggcagtta ttggagttct cagtgctgtt
    37861 gactttggtg gcccacttaa taaaacagtc tatgcctttg tgttgacttt acaggctgaa
    37921 ggtgtgaaag aaccattgac tgctttgcaa ttggtgaata ctgctacacc agttggattt
    37981 ggattggcct attttatcgc gaaattactc aaaaaaaata tctatactca agaggaaatc
    38041 gaaacattga aatcggctgt tcctatgggg attgtcaata ttgttgaagg tgtaattccg
    38101 attgttatga ataacttggt tccaggtctc attgcaacag gtatcggtgg tgctgttggt
    38161 ggtgctgttt ctttgacaat gggtgctgat tctgccgtgc catttggtgg agtgcttatg
    38221 ttaccaacca tgactcgtcc agtagctggt atttgtgctt tgttagccaa cattgtagtc
    38281 acaggacttg tctacgcgat tttgagaaaa ccaataaaac atacagaacc agttatgact
    38341 gttgaagaag agattgattt gtcagatatt gaaattttgt aagagggtaa cgatgtcaag
    38401 aattgaattt tcaccatctt tgatgaccat ggatttggac aaattcaaag agcagattac
    38461 ttttttgaat gataaagtag catcttatca tatcgatatt atggatggcc attttgttcc
    38521 caatattacc ttgtctcctt ggttcattca agaagttcaa aaaattagtg acacaccttt
    38581 atcagttcat ctgatggtca cagacccaac cttttgggta gatcaagttc tcgatttaca
    38641 atgtgagtat atttgtattc atgctgaagt tctgaatggt cttgcttttc gtttgattga
    38701 taaaattcat gatgcaggtc taaaggctgg tgttgtcctt aatcctgaaa cacctgtttc
    38761 tacaatcttt ccctacattg atttacttga caaagtaact attatgactg tagatccagg
    38821 ttttgcagga caacgctttt tggagtctac cttgtataaa atccaagaac tccgtcagct
    38881 tagagttcag aatggttatc actacatcat tgagatggat ggttcttcga gtcgtaagac
    38941 tttcaaacaa attgatgtgg caggaccaga tatttatgtt ataggtcgca gtggattatt
    39001 tggtttggat gacgatattg ccaaagcctg ggatatctgt tctagagatt acgaagaaat
    39061 gaccggaaaa acaatgccaa tcaaataatg gtttgagaag aaatttatta gttaggagga
    39121 atatatgtca ctacaatcag ttaacgccat tcgttttctt ggcgtagatg ctattaacaa
    39181 atctaattct ggtcacccgg gaatcgtcat gggtgctgcg ccaatggctt atagcctatt
    39241 tacaaagcac cttagaatta cacctgagca gccaaactgg attaaccgag atcgctttat
    39301 cttgtctgcg ggtcatggat caatgctact gtatgctctc ttgcatttaa cagggtataa
    39361 ggatgtatcc atggacgaga ttaaaaattt ccggcaatgg ggatctaaga cacctggtca
    39421 tcctgaagtg acgcatacgt ctggtgtgga tgcgacatct ggtccgcttg gtcaggggat
    39481 ttctactgcc gttggtttcg cccaagcaga gcgtttttta gctgctaagt acaacaaaga
    39541 tggttttcct atttttgacc attatactta tgttatcgct ggagacggtg acttcatgga
    39601 aggagtgtct gcggaggcgg cttcttatgc aggtcatcaa gctttagata agcttatcgt
    39661 cctctacgac tccaacgata tctgcttgga tggtgagacc aaagatactt tctctgaaaa
    39721 tgttcgcgcc cgttacgatg cttatggttg gcatacagtt ctggtagaag atggaacaga
    39781 tttagcagca atttctacag caattgagac ggccaagttt tctggtaagc cgagtttgat
    39841 tgaagtgaaa acggtaattg gttacggctc acccaataaa agtggtacaa atgctgttca
    39901 tggtgcacca ctaggagcag aagaaacagg agcaactcgt aagtttttgg gatgggatta
    39961 cgatccattt gaagtaccag aggaagtata ttctgatttc aagacaaatg tagcggatcg
    40021 tggtcaggag gcatacgatg cttgggctag tttggtgtct gattacaagg ttgcttatcc
    40081 cgaagttgct agtgagattg acgctattgt agctggaaaa tcccctgtaa ccattactga
    40141 aaaagacttc cctgtctatg agaatggctt ctctcaagca actcgtaatt cgtcccaaga
    40201 tgctattaat acagcagcag cagttttacc aaccttctta ggtggatcgg cagacttagc
    40261 tcactccaac atgacctaca tcaaggcaga tggcttacaa gataaatata atccattaaa
    40321 ccgcaatatt cagtttgggg tacgtgaatt tgccatggga acaatcctca atggaatggc
    40381 tcttcatggt ggtttacgag tttatggcgg aaccttcttt gttttctctg actacgtcaa
    40441 agctgctatt cggctatcag ccattcagga gttgcctgta acttatgtct ttacccatga
    40501 ttcaattgcc gttggtgaag atggtccaac tcatgaacca gttgaacatt tggcaggttt
    40561 acgctcaatg ccaaacttga ctgttatccg tccagcggat gcccgtgaaa ctcaagcggc
    40621 ttggcatcat gccttgacca gtaccaccac tccaactgtc attgtcttaa cccgtcaaaa
    40681 cttggtagtt gaagaaggga cagactttgg taaggtcgct aaaggagcct acgtcgtgta
    40741 tgataccccg ggatttgata ctattatcat tgctacagga tctgaggtca atctagctat
    40801 caaagctgct aaggaattgg ttttacaagg tggtaaagta cgtgtggtat ctatgccctc
    40861 aaccgaacta tttgatgctc aagatgctac ctacaaggaa gacattttac catctaagac
    40921 tcgtcgtcgt gtggccattg aaatggcagc gacccaaagt tggtacaagt atgttggttt
    40981 ggatggcgcg gtcatcggta ttgacatctt cggtgcgtct gccccagctc agactgtgat
    41041 tgataattat ggatttacgg tagagaatat cgttgctcaa gttaagtccc tatagaaacc
    41101 aattacaatg aagatacagc tgttgtcaga ctagcagatg tagtgataga cactaatcag
    41161 atgattggtt atttaaaaac tataatgaga atgtaataat ttatctacga aagttataat
    41221 agatagtata cacaatagag tatactctga aacggttgcg aagtacgcta atcactttgc
    41281 tactgatcta gatagtttct ttaatcaata aacacagcat ccacagattg acttaggata
    41341 ttgtaagttt tttgaaagct agagagaagg tctctaaaat taaaaaacgc atagcatagg
    41401 atgttaaaat gaactgaccc caaaagttag acagaaaaaa tctaactttt ggggtgtttt
    41461 tattatgaaa ctaacttatg atgataaagt tcagatctat gaacttagaa aacaaggata
    41521 tagcttagag aagctttcaa ataaatttgg gataaacaat tctaatctta ggtacatgat
    41581 taaattgatt gatcgttacg gaatagagtt cggcaaaaaa ggaaaaaatc gttactattc
    41641 tcctgattta aaacaagaa
//
LOCUS       DAVKZI010000017        38514 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKZI010000017 DAVKZI010000000
VERSION     DAVKZI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.017"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(178..1275)
                     /locus_tag="VXB18_001018"
     CDS             complement(178..1275)
                     /locus_tag="VXB18_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0382237.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(1285..2031)
                     /locus_tag="VXB18_001019"
     CDS             complement(1285..2031)
                     /locus_tag="VXB18_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0382238.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(2134..2487)
                     /gene="rsfS"
                     /locus_tag="VXB18_001020"
     CDS             complement(2134..2487)
                     /gene="rsfS"
                     /locus_tag="VXB18_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0382239.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(2500..3000)
                     /locus_tag="VXB18_001021"
     CDS             complement(2500..3000)
                     /locus_tag="VXB18_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0382240.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(3001..3594)
                     /gene="yqeK"
                     /locus_tag="VXB18_001022"
     CDS             complement(3001..3594)
                     /gene="yqeK"
                     /locus_tag="VXB18_001022"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0382241.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(3594..4223)
                     /locus_tag="VXB18_001023"
     CDS             complement(3594..4223)
                     /locus_tag="VXB18_001023"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0382242.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(4275..4586)
                     /gene="yhbY"
                     /locus_tag="VXB18_001024"
     CDS             complement(4275..4586)
                     /gene="yhbY"
                     /locus_tag="VXB18_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0382243.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(4800..5906)
                     /gene="yqeH"
                     /locus_tag="VXB18_001025"
     CDS             complement(4800..5906)
                     /gene="yqeH"
                     /locus_tag="VXB18_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0382244.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(5909..6499)
                     /locus_tag="VXB18_001026"
     CDS             complement(5909..6499)
                     /locus_tag="VXB18_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0382245.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(6451..7359)
                     /locus_tag="VXB18_001027"
     CDS             complement(6451..7359)
                     /locus_tag="VXB18_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0382246.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNFFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(7416..7976)
                     /locus_tag="VXB18_001028"
     CDS             complement(7416..7976)
                     /locus_tag="VXB18_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEV0382247.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            8115..9324
                     /gene="sstT"
                     /locus_tag="VXB18_001029"
                     /pseudo
     CDS             8115..9324
                     /gene="sstT"
                     /locus_tag="VXB18_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            9392..10345
                     /locus_tag="VXB18_001030"
     CDS             9392..10345
                     /locus_tag="VXB18_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0382248.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            10489..10869
                     /locus_tag="VXB18_001031"
     CDS             10489..10869
                     /locus_tag="VXB18_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0382249.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            10968..11189
                     /locus_tag="VXB18_001032"
     CDS             10968..11189
                     /locus_tag="VXB18_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0382250.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            11206..11520
                     /gene="trxA"
                     /locus_tag="VXB18_001033"
     CDS             11206..11520
                     /gene="trxA"
                     /locus_tag="VXB18_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0382251.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            11826..12359
                     /gene="queF"
                     /locus_tag="VXB18_001034"
     CDS             11826..12359
                     /gene="queF"
                     /locus_tag="VXB18_001034"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0382252.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQHHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            12409..12588
                     /locus_tag="VXB18_001035"
     CDS             12409..12588
                     /locus_tag="VXB18_001035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382253.1"
                     /translation="MLKAVFEVVDKTDEVSLKHCFEVADRTDEVSNHTYDKVKLTWFE
                     EIFEEYHTKKPCSSR"
     gene            complement(12613..13281)
                     /locus_tag="VXB18_001036"
     CDS             complement(12613..13281)
                     /locus_tag="VXB18_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0382254.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(13392..14183)
                     /locus_tag="VXB18_001037"
     CDS             complement(13392..14183)
                     /locus_tag="VXB18_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0382255.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLIFTSF
                     AKGIQEELFIQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLSADANQ
                     QSVFYQGLQSEIRDDLSNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(14608..15372)
                     /locus_tag="VXB18_001038"
     CDS             complement(14608..15372)
                     /locus_tag="VXB18_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382256.1"
                     /translation="MFKLSFQSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(15365..16015)
                     /locus_tag="VXB18_001039"
     CDS             complement(15365..16015)
                     /locus_tag="VXB18_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382257.1"
                     /translation="MGILGINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSK
                     SCLGIVGQEDMLDMTLNVYDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVN
                     QLSSGMRRRLVLARALINRPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITS
                     HYMNEIEYLTDRVLMLHQGTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            16382..17059
                     /locus_tag="VXB18_001040"
     CDS             16382..17059
                     /locus_tag="VXB18_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382258.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            complement(17119..18915)
                     /gene="pepF"
                     /locus_tag="VXB18_001041"
     CDS             complement(17119..18915)
                     /gene="pepF"
                     /locus_tag="VXB18_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0382259.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(18926..19669)
                     /locus_tag="VXB18_001042"
     CDS             complement(18926..19669)
                     /locus_tag="VXB18_001042"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0382260.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(19671..20621)
                     /locus_tag="VXB18_001043"
     CDS             complement(19671..20621)
                     /locus_tag="VXB18_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0382261.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(20634..21653)
                     /locus_tag="VXB18_001044"
     CDS             complement(20634..21653)
                     /locus_tag="VXB18_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0382262.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            complement(21704..23887)
                     /locus_tag="VXB18_001045"
     CDS             complement(21704..23887)
                     /locus_tag="VXB18_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV0382263.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDSPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            complement(23949..24983)
                     /locus_tag="VXB18_001046"
     CDS             complement(23949..24983)
                     /locus_tag="VXB18_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0382264.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGVSK
                     SSVSRELSED"
     gene            complement(25093..25251)
                     /locus_tag="VXB18_001047"
     CDS             complement(25093..25251)
                     /locus_tag="VXB18_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV0382265.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            complement(25232..26320)
                     /locus_tag="VXB18_001048"
     CDS             complement(25232..26320)
                     /locus_tag="VXB18_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0382266.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVRKDVVQTHKAMKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(26339..26809)
                     /locus_tag="VXB18_001049"
     CDS             complement(26339..26809)
                     /locus_tag="VXB18_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0382267.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(27100..27552)
                     /locus_tag="VXB18_001050"
     CDS             complement(27100..27552)
                     /locus_tag="VXB18_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0382268.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(27589..27762)
                     /locus_tag="VXB18_001051"
     CDS             complement(27589..27762)
                     /locus_tag="VXB18_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0382269.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            complement(27905..28084)
                     /locus_tag="VXB18_001052"
     CDS             complement(27905..28084)
                     /locus_tag="VXB18_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382270.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(28249..28488)
                     /locus_tag="VXB18_001053"
     CDS             complement(28249..28488)
                     /locus_tag="VXB18_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382271.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            28758..30029
                     /locus_tag="VXB18_001054"
     CDS             28758..30029
                     /locus_tag="VXB18_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0382272.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            30294..30366
                     /locus_tag="VXB18_001055"
     tRNA            30294..30366
                     /locus_tag="VXB18_001055"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30327..30329,aa:Lys,seq:ctt)
     gene            complement(30574..31893)
                     /locus_tag="VXB18_001056"
     CDS             complement(30574..31893)
                     /locus_tag="VXB18_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0382273.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHMDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(31903..33519)
                     /locus_tag="VXB18_001057"
     CDS             complement(31903..33519)
                     /locus_tag="VXB18_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0382274.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFTFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            complement(33548..34438)
                     /locus_tag="VXB18_001058"
     CDS             complement(33548..34438)
                     /locus_tag="VXB18_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0382275.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            complement(34449..35366)
                     /locus_tag="VXB18_001059"
     CDS             complement(34449..35366)
                     /locus_tag="VXB18_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0382276.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            complement(35516..36517)
                     /locus_tag="VXB18_001060"
     CDS             complement(35516..36517)
                     /locus_tag="VXB18_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0382277.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            complement(36878..38359)
                     /locus_tag="VXB18_001061"
     CDS             complement(36878..38359)
                     /locus_tag="VXB18_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0382278.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKEISHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT        11592 a         8335 c         6701 g        11886 t
ORIGIN      
        1 tataccacaa aataacaagc ataaagcgga ttcaaagata aagattaagg ttcatatact
       61 aattttcttt attgactttt tgtcttctgt attagggagt ttatcatttt ccaaaaactt
      121 tatcttcaat ttgttatcta aaatttctac aataaaaaag cctacctttc ggtagactta
      181 gtttgtttct attctaatcg gcactcttcc aaaattttgc tctgctatac ttggctttcc
      241 tagttggtaa atctggtcaa ccttttgagt catagcatcc caaggttctt tgccaattcg
      301 gctgactaga ttgacctgtc ctttcagaga cttgagatgt tgcctgcctt tttcagtaaa
      361 tccaaggaca tgaatggctt ctggcaagac attttctcta gcctgcacca aaatataggt
      421 caataggcgt ctgacacgcg ccttggtgta acgtttggta gtcactaact cgaccaattc
      481 ttccacagac tgggctgttt taatagcttc tttaatgcgc acagccattt cttgattgac
      541 ctgatagatg gtggttaggt cgggatttga caagatttga tagcggagca agggaaaata
      601 gtcttcccag atcaccttac tggcctgctc aaatagggca acagaaggca taaaacgttc
      661 taagaaatct tggtccttct gatgttgacg gagggctgtc gccgaggcaa agtccacatc
      721 tttattcaca gaatggtaac ctgccccctg acgctgaatc ggatgcagct tgatatttcg
      781 tcctgcaacc gccttggcat aggccagagc aagaacatga ttgggggtat tacctgaaaa
      841 atcaagacca gcaaattcct tccacatagc ttgggttttc tggggatagg aaagggaatc
      901 aggcagattt tccacaaatt tctccatctc agcacctttc tctgtgtata agtcagcaat
      961 tttctgataa tctcgaactt cctctgtccc aaaaactaga ctatcaatgc ccaagcgatc
     1021 caagatatcc atagctcctt gaccaaagaa atcagctgcc tgaacactga ctaaaaaggg
     1081 caattccact accaagtctg cgccattttc cagcgccatc tgggtccttg tccacttatc
     1141 cacaatagca ggctctccac gctgcatgaa attccctgac atggcaacaa ttttcagtcc
     1201 ctctgcctga tccagcaggt atttatggcc attatgaaaa ggattgaact ccgcgataat
     1261 acctgttatg gtcatgctaa tctcctactt ctgcgccaca aaaaaccaac gggtgctagt
     1321 ttctgttggc tccttatcct caaagtctgc atagagtttg aaggacttaa atccagcctg
     1381 ttccagcaag atatcatagg tcaagatctc ataggtcctc tcctcatgta cttcatcgtg
     1441 gcgactaaag gaaccgtcag cctccttgat aaagaaagtc agctcatgca cgatggagtg
     1501 aggagcttcg tcctcatatg tatcccaaag catggcaaaa tcttccgcat tttcatggta
     1561 ggaatagcca gggaatactt catctgtctg gtaggtcgag tgcacgtcaa agatgaaaac
     1621 tccctcttca ttcagcgcat tgtacacgtc cttaaagacg tcccctactt ccacctcatc
     1681 ctgcatatag cagatagagt ccgaataaca cgtgacaaaa tcgtatttcc ctgccttgga
     1741 caaattcagc atattacctt ctataaaagc aatcttttgc ttggctgaag ttgctctctt
     1801 ctccgcaatc ttcaacatat ccgcactcaa gtcaagtcca gtcacatcaa aaccagcctg
     1861 agagaagcgc actgattgaa ttcctgtccc acaagccaat tccaagagtt tctttctctc
     1921 cttagtctta ggcaaatgac gcagagaaaa attcgtccat ttgtcgtata aactatcgtc
     1981 catgaccgca tcatagaccg ccgcaaaggt ttcataagtc gccataatca tgatactaag
     2041 agctccatgg taaacaccac tagcccttta cctttctatc aatttttcta aaataagcaa
     2101 agaaacccag ttgactacaa ctgagttcat cttctaagca agagcttctg aaatatctac
     2161 tgaattcgcc tcatgccata gcttctctag attataatgg gcacgcattt cttctgaaaa
     2221 gatatgcacg acaacagcac cgaggtccag taagacccag cctccagctg catcgccttc
     2281 gacatggcta cctttaaagc ctgcttgagc tactttttca cggatattag ctgcgatagc
     2341 gtccaactga cggctattca ttgagctagt gatgacaaag tagtccgtca cactagtcaa
     2401 atcttgtaca tcaagtgcga ggatatcctc cgcacgtttc tcatcagccg ctttcacgac
     2461 tagttctagt aattcttttt cgttcattta atcctctttt tagaaaatat gtttgtaatc
     2521 taggacatct gcaaagcgct cctcccaaat gtcctcataa aattcattaa tcgtttctgc
     2581 tggaatgtca tccccatcaa aggttgtgac agcaccttct ggaacaataa gctgatagcc
     2641 atattcaaag gcaaccttga cagaggtatc cacacaatat tctgtctgca taccacataa
     2701 aactaatttt tcaatcccct gtttatccaa gtattctttt aagccagttt ctttgaaaat
     2761 actgttatac ttcttctgaa agaccttttc agcaggtttt cgatttaaaa gcgcagataa
     2821 ctgccaatct tctgatgttt gagcttcaga gttctcaata tgttgaacat agataatttc
     2881 aatattcttg cttctagcct ggttttgtaa ataagaaatt ttttccaata gactttttgt
     2941 ctggaaccca gtttctacta aaacattctg aacatcaatg attataaaag ccgtcttcat
     3001 ttagtcctct ttcaaatagt gcacaaaggc gttataggtt tcaagggttt ggggatagat
     3061 ggggaatccc tgatgagcta gatactccac ggtacgagct gtttcgtagg ccaccgcctt
     3121 attgagcgat agacttgcaa tctcacgcgc cacatctact ccaggaaagg ctcgattgtg
     3181 ctcgatatag tctgcgacgt agatgacctt atctaggtct gtcatttgac cagcaccgac
     3241 tgtatggact tcaatggctc gcaggatttc tgaatcatgc aaatccaaat cttcctgaat
     3301 tttgtaaatt ccgaccatac catgccagac attattgccc cagtttttga ggtcagggtc
     3361 tagctggtaa cggtcaatca agtctagaaa ttcctgatct gacaactttt tagcatagtc
     3421 atgaagaaga cctgctagac ttgctttctc aacatctaca ccaaagcgct gagctaattc
     3481 catagcggca cgctccacac ctagacaatg ggttagacgt ttctcaggta gaagctctgc
     3541 cattttttcc aacaaagcct cacgggagca gttgatatag tcttgatagg acatcagtag
     3601 agcccctcct tctcgatgta gtctagcact ggctgaggta ggagaaagtt gggtttccga
     3661 ccttgggcaa ggaaggcacg caccatgctg gacgagatat ccatgagcgg tacgtccacc
     3721 cagataactg gataggaagt ccctaccttg tagcgtggac gctgaacccc cacaaactga
     3781 accatgtcaa ccagttcatc aattcggtac cacttaggca gatagtcaac catgtcggca
     3841 ccgatgataa agtaataatc cgtatctgga ttcttctctg tcaaaatctt catggtgtcg
     3901 taggtgtagg aaataccctt gcgctccaac tcaatggttt caatgactag gccgtcaatt
     3961 ccctcaattg ccaactcaag catcttgaga cgatggtgtt cagggatggt ttccttttta
     4021 tcaacgtgag gaggttggta ttcaggcatg agcagaactt gatccagtcc caactgttgc
     4081 cgtacttgat ccgcaacaat gagatgggca ttgtgaacag ggttaaaatt cccccctaaa
     4141 atcccaactt gtttgcgttt tttctccttg atttctggct ccaactctac cttggtaaag
     4201 ggagtcaata gttcgattgt cataggctag tcccctttat ttctctataa aaacagttat
     4261 ttggagtttc ggtcttagat ttctttgact ttcttagaaa tcttgcgatt ttctttcttg
     4321 ctagattgtt taaacaaaat caagatgcgt cctatttttt ggactgtatc cacaccgatt
     4381 tcttcttcca aaatttcagc tacttcgtgg atgttttcat ctgtgttttg taagagagta
     4441 accttgatta attcacgcgc atcaagagct tgacggacgc tggttttgat ttggtcgttg
     4501 agtccatttt tcccgatttg gatgataggt ttgagggtgt gtgcctggct gttgaggaag
     4561 gcacgttgtt ttgatgttaa tgacataatt ttcttccttg ttttttgata gttattttag
     4621 gtggtgaggg acggtcggaa ctaattttcc aaagatttca tctttgaaaa atggatttcc
     4681 tgacctcaca attgagcctt ggtctcaatt gtgccccttg ccaatctaca gattggcaat
     4741 cacaccacgg caataactat cgctatatga gctcactttg ttcgctcagc gattttgttt
     4801 taaataattg cttttcgtgt gacgacggcg acgccttctg gtgcccagac ggcgactttt
     4861 gctgtgcctg ttacacgaat ccatcctagg cctgagatga ctaggtctgt cttatcttta
     4921 atggtaaaga catgctggac tagccttggg aaatcttctt tttccttgct atttggtggt
     4981 gtcaaaagag ttcccaggtg cttatcgtag aaagcactag ctccttcaag cttgctacga
     5041 tggagtttga gttcattatc aaagaaagca gtaaatcctt gcttttctcc tgctataaag
     5101 tcaaagcgtc ccaaaccacc taaaaatagg gtttgctcag gattaagctg ataggtctta
     5161 ggcttgattt cctttttagg actgacatac ttgaggtttt tggccgtcaa gtagtgagcc
     5221 atctggtggc ggtggataat tcccggcgta tcgtaaatat aagatccgtc gtcaagcgga
     5281 atctctattt tgtccaaggt tgtccctggg aagcgtgaag tagtgatgac attctgatca
     5341 cccgtgattt cttggataat agcattgatt agagttgatt ttccaacgtt ggtcacaccg
     5401 accacataga catcgcggcc cttacggtag tgttcaatct tgtcaatgac ttccttaatg
     5461 gcatgtttat tttgtgctga agttaggacc acatcgactg gacgaagacc ttcttcatgg
     5521 gcacgtttca tgagccactg gctaatctta ccagacttaa ctgacttagg aaggatatct
     5581 tttttatttc ctaccaagag gacatcattg cccgagacga aacgtggtaa acctgggatg
     5641 acagatccat taaaatcaaa gatatcaatg acattgacca ctaaagcatc actgtctccc
     5701 acctcgtgca agagcttgag gaaatcatcg ttcgtcaact ggacatctgt gatttcattg
     5761 tagtggcgga gacggaaaca gcgttggcaa tagacttcgc cagtctccaa acctttttca
     5821 agtgccgact ggggggtaaa accaagacca gctttatctg tcgtctgaat ggttgctcca
     5881 caaccaatac agagaatttc ttccatagtt aaattccttt tttatatgta atcggtccgt
     5941 acttttcagt gatttttctc ataacacgac gctcacgagt tcggttaatc tgcgttttga
     6001 ttgagtcatg ttggaccaag ggtttgacta aaattgaccg aatccctgca cggtgggctg
     6061 ctcgtatatc tgtcatgagc tggtcaccaa ccatgaccac ttcctttttg tcatagtgga
     6121 attccttcat agcacggtca ataccaaatg tgaagggctt caaggcccag taaacgtaat
     6181 caatcccaaa tttctcaact gctcgttgaa cgcgtttttt ggtgttattt gacactacga
     6241 taatgccaat acccgcgtcc cgaaggtcat gtagccattg cttcatctct ggcgttccat
     6301 cagggttgtt ccaagcaatg agggtattat ccaaatcgac caaaacagcc ttgattccct
     6361 gcgcctgcag gcttgggact gtcagatcat agactgcttc cacagcaaaa tctggtatat
     6421 aattttcaat cgccattctg gctccttttc ttaacttttt ttcgcaattt tccttagtaa
     6481 caaggataaa acaatccaca aacctgcact agccaaactg atatagagcc aagcatgggg
     6541 ctcatctgtt aaaggtaagg gaacattcat tccgaaaaag cctgtcacga ctgccaaaac
     6601 agctagcaag actgaaatga tagtcaaggt tgtcaaattg tcattcagat tattgtttag
     6661 aatattgttg taagaggctg aaagctgctg taaaatctga gagattaggt ctgtcatgga
     6721 taccagctga tgagcctcaa tcatggcatc atcaaactgt tctctctcaa tctcatcaaa
     6781 actacgatac aaggcatgac cttgaatatg ctctaacaaa atccgatttt gtttggcagc
     6841 tgccgtcaga taaaccatac cagtctccaa atcagacagg gcaaagaagt ttttcttggt
     6901 agttcgctgg cgcaagaggt cattgacctc atccctactc ttgtccatct gctcaatgac
     6961 aggatagtag gcattgctga tgatttccag actggcaaag agaaacttat aaatcgaaag
     7021 cgtgtcatgg ttctccagat aacgagtcat ctgttcaatg acataggcgt tcttggtatt
     7081 actaatggta atcaggcgac gatgctcgac aataaaggtc atgggaaaag tctcatagta
     7141 ggccttgtcc ttttttacgt ctaggacatt atagataaag gtaaccgtcc cactttcacg
     7201 gtggtagtcc atgtgggcgc gctcgtttct atccagtgcg tattcaatgg tttccttgtc
     7261 caaaccgtaa atttcagaaa ggtcttctag tttattcaac tttcctaggt ctaggtctat
     7321 ccaggtacaa ccattgccca actgcttttc taaaaccatc ttttctcctt attaaactcc
     7381 ctctattgta ccacaaatta cttaaaataa caggtctagt ctgtgcgtga gaaattgcta
     7441 acaactgtga tatttcggtt agggacaaag tgaaggactt gctcctcgct acgaagctgt
     7501 gtcgtacgaa ttcccacact gacaacctta cccgatacag taatcggtcc atttgtcaga
     7561 acgacctcat ctcccacatc cagttgacgt tcaaagagga tgaaaaagcc attgatgaca
     7621 tcagacagaa agccttgggc tcccatacca atcgctaccc cagcaatacc agctccagcc
     7681 agcaaactag aaactggcaa acctaaaatc gacaaaatgc agtagagtaa aaagaaatat
     7741 agcgtataat taaacacatt ttctagtaaa cgtgagatgg ttttttggcg tccgacatca
     7801 tgacgagaca tttttagaga aggtttgaca attctctgca ccatggtatg aagcattttt
     7861 ttagcaatat aaaatacaat caaaagcagt aaaagagaaa tgaccttggt tagaatattc
     7921 tcgataatgg ttgtcacatc tagcttttca atataagcct gaataaattt ttgcatataa
     7981 aactccttta tttcattata ccatattttc atcagtctca ttctccataa atattcaaaa
     8041 aatagacaga aaattcttga ttttgtctat catttatact ataatcataa tcactacaca
     8101 aaaaggagat tattatgaaa agaatcattc atgcttggaa taaggcaagc cttgtcaagc
     8161 gtatcttgat tggtatgctt tatggggaat cctaggactg acccttccta atctctcagg
     8221 gattgggcta ctcggggatt tattcgttgg aggtctaaaa gctgttgctc ctatcctagt
     8281 ctttgccctc gttgccaatg ccctttccca acatcaaaag ggacaagata gcaatatgaa
     8341 aactgttgtt ttcttgtata tcctatgata gggactttcg ccgctgctct tgtagctgta
     8401 ctagcaagtt tcatcgtccc tattgaaatt accctaaata gtgccaatac tgaaattgca
     8461 ccaccagatg ggattgggca ggtcctcagc aacctcttgc tcaaactggt tgacagccca
     8521 gtcaacgccc tgcttactgc taactatatt ggaatcttat cttgggcagt catttttgga
     8581 atcgctatga gagaagccag taaaaatagt aaagaattgc taaaaactat cgctgacgtg
     8641 acttctaaaa ttgtcgaatg gatcatcaat ctggctccat ttggaatcct tggtcttgtt
     8701 tttaaaacca tttctgacaa gggagtcgga agccttgcca actacggtat tttattggtt
     8761 ccattagtaa cgactatgct ttttgttgcc cctgtggtca accctttgat tgccttcttt
     8821 tttatgagac gcaatcctta ccctctagtt tggaactgcc tccgtgtcag cggtgtgaca
     8881 gcctttttca ctcgtagttc tgcgactaac attcctgtca acatgaaact ctgccatgac
     8941 cttggactca acccagatac ctattctgtt tctatcccac tcggttctac tatcaatatg
     9001 gctggagtag cgattaccat taaccttttg acccttgctg cagttaacac tcttggaatt
     9061 cctgttgact ttgccacagc ctttgtcctc agtgtggtag cagctatctc agcctgtggt
     9121 gcttcaggta ttgccggagg ttccctcctt cttatcccag ttgcttgtag ccttttcggt
     9181 atttctaacg atattgccat acaagttgtt ggggttggtt ttgtgattgg tgtcatctaa
     9241 gactcatgtg aaacagccct taactcttct acagatgtcc tctttaccgc cgttgccgaa
     9301 tacgcagcaa cccgtaaaaa ataactcatc aaggcaagcc tgctcatgtc ttatctttta
     9361 cgcttttatt ctaacttatt aggaaattct tatgtctatt agccaacgta cgaccaagct
     9421 catcttagct acctgtcttg cctgcctgct tgcttatttt ctcaatcttt cgtcagcagt
     9481 ttcggctgga attatcgctc tcttgagcct atctgatacg cgtagaagta ctttaaaact
     9541 ggctcgcaat cgtctttttt ctatgcttct agctctggct atcggtgttc tagcttttca
     9601 cttgagcgga tttcatatct ggagtctcgg cctctatctg gccttctacg ttcctttagc
     9661 ctacaagatg ggctgggaaa ttggcatcac accaagcact gttttggtta gccatctctt
     9721 ggttcaagag tcaacctctc cagaccttct agtcaatgaa ttccttctct ttgctattgg
     9781 tacaggattt gccttgcttg ttaatctcta tatgccttca cgagaagagg aaatccagca
     9841 ctaccacacg ctggtggaag aaaagttaaa agatatcctc cagcgcttca aatactattt
     9901 atccagagga gacggacgca accgagcaca gctggtagca gaattagaca cgcttttgaa
     9961 agaagccctc agactggtct atttggatca ctctgaccac ctctttcacc agaccgacta
    10021 ccatatccac tactttgaga tgagacagcg acaaagtcgt atcctgagaa acatggccca
    10081 acagattaac acttgtcacc ttgccgccag tgaaagcctg atcttagcgc aactcttttc
    10141 aaaaattgca ggtcaactga gccagaccaa tcctgcttct gatttgctag atgaaattga
    10201 acgttatctg gaagtcttcc ggaaccgcag tctgcccaaa acaagagaag agtttgaaac
    10261 ccgcgccacc cttcttcaac tcctacgtga agccaaaacc ttcatccaag taaaagttga
    10321 tttttaccaa aaatatagac agtaaaaaat aaaaccacta aaaaacagag cttgccagca
    10381 ttcttgaaaa gtagtataat tattgcatgc gcaatcatct tgtgacgcag agactgcccg
    10441 ttaatggact ttcttctata ttatgactct aaaaagaaag gagacactat gacctatttg
    10501 gaaaaatggt ttgacttcaa tcggcgtcag aaagaaattg aaagtctctt ggaagagacc
    10561 attgcccaac agagcgagca aagtctgacc ttgaaagagt tctacctgct ctactatctg
    10621 gacttggctg aagaaaaatc tctacgccag attgacctgc cagataaact tcatctgagc
    10681 ccgagcgcag tttctaggat ggtggctcgc ttggaagcta aaaattgcgg tctactcagt
    10741 cgcatgtgtt gccatcaaga tagacgctct agttttatct gcctgacaaa tgatgggcaa
    10801 aagacactgg cctcgctaca aaagactgtc gaagaaagct tggaagcagg tttggatttc
    10861 ttgatttaag atgattttaa aaaaagttgc gtgcgcaatc atttttcttg acattctctt
    10921 ttataaggag taaaataaag ttagcattaa acaaaggagt tttaaatatg attgaaatta
    10981 cctatataga tgccagcaag aacgaaagaa ctgtgacttt cgagtcttat gaagactttg
    11041 aacgttcaca acaagcttgc cttatcggcg tcgcagacta ctaccctgtc caaaaattaa
    11101 cttacaaggg tcataatttg gactaccatg ggacttatgg agatatcttc ttctatctca
    11161 tgaaacaaga tttaagccaa tataactaaa aaaaggagaa atacaatggc aaaagcaatt
    11221 acagatgcaa cattcgaaca agaaacaaaa gacggtttgg tcttagtaga cttctgggca
    11281 acttggtgtg gtccatgtcg tatgcaaggt ccaatcttgg acaaattgtc tgaagaactt
    11341 tcagaagatg tcttgaaaat cgttaaaatg gacgttgatg aaaatccaaa cacagctcgt
    11401 gcttttggaa tcatgtctat tccaactctt ctcttcaaaa aagacggcca agttgtcaaa
    11461 caagttgcag gtgttcacac agcagaacaa atcaaggcca tcattgctga attgagctaa
    11521 tcaaacgaga gaccaagtac tttatttggt ctcttttttc ttgccctttg ccatttttca
    11581 aaaaatatgc tagactatag tagattgaaa ctagaatagt acacctctac ttctaaaaca
    11641 ttgttaaaaa tcgatttgac tgtcctgatc gatttatcct gtttttattt cattttacta
    11701 tataagtaga atattacgat gtttgggata tgccatcgct aaaaaaaact cgatttggta
    11761 ttttttagtt ccctaatggg agctttttgc gtgctctgaa catttcccat tttggaagga
    11821 gtactgtgaa acgtcaatca gccttggtcg tctttagtgg tggtcaagat tcaacaacct
    11881 gccttttctg ggccatgcaa cactatgaaa cagtcgaagc tgtcaccttt gcctacggcc
    11941 aacatcatca cctcgaaatt caaattgcta gagaaatcgc caaggaacag ggcattcgtc
    12001 accatatcct cgatatgtct ctgctgggac aaatcactgc tcaaccagac tttgcgacga
    12061 ttcatatttc ctacattcct gacaagctct gtgtcgagtc aaaatccctc aaactatatc
    12121 tatttagcta ccgaaatcac ggagatttcc acgaaaactg tatcaacacc atcgggaaag
    12181 acttggtcaa cttgctagac cctcgctatt tagaagtctg gggaaaattc actccgcgcg
    12241 gtggcatttc aatcgacccc tactacaact acggtaagca aggaactaag tatgagggct
    12301 tggcagaaca acgcctcttc caacacgacc tttatccaga gaaaattgac aaccgctaaa
    12361 gtcatactca atgaaaatca aagagcaaac taggaagtta gccgcaggtt gctcaaagca
    12421 gtgtttgagg ttgtcgataa aactgacgaa gtcagcttaa aacactgttt tgaggttgca
    12481 gatagaactg acgaagtcag taaccatacc tacgacaagg tgaagctgac gtggtttgaa
    12541 gagattttcg aagagtatca tacgaaaaag ccctgttcct caagatgagg agcaaggctt
    12601 tttgagtttc aattattctt ctgttccaag gaaatttttt gcaacaaggg ctgcaagaac
    12661 tccaccagcg attggtgcaa ggatgaaaat ccaaacttgt tgaagggctg cgccgcctac
    12721 caagacagct ggtgccaagc tacgagctgg gtttactgaa agtccagtaa tcttcaatcc
    12781 gacaagaatc atcgccatca atgacaaacc gattaccaaa ccagcaatcg cgccattgcc
    12841 cttgctttct gaagtcacag tcatgataac caatacaaac aagaaagttg cgatgacttc
    12901 aaacaagaaa ccaccaaaga cagtgacacc gtttgccaag gcattttcac caagactagc
    12961 agttgacata cctgagttag ccaagaggaa gaagacagcg ccagaagcga tgaaagctcc
    13021 aacaacctga ccaaggatgt agtttacaag ttctgaagat gacaaacgtt tgtttacaaa
    13081 catagcaatc gaaacagccg ggttcaagtg agcacctgaa acagttccga ttgagtaggc
    13141 tgccaccacg attgccaaac caaaggcaaa ggcgattcca aggtgaccaa ggccatcaag
    13201 accatttcca aaaacaacag ctcctgtccc gacgaataca agcatgaacg taccgattaa
    13261 ctcagcaaca aattttttca ttttctttct ccttttttca aaaactagat actagtctat
    13321 caaaagtagg aaagggtttc aagaaaattg attggaaatt ttttgaaaat catagaacta
    13381 ttagctaatc tctagtattg aaaagactgg atagcttctt tcaactcatc ttgtaaacta
    13441 tttctctggt caagttggac atagacttcc accagacagg atctaaagtt ggaaaatttg
    13501 gaaaaatcct ccctttcttc tatcggaaaa tcaacagttt ttatccaaga agctacttgt
    13561 tcttgctcca acttcccttg taaaataggt tcatagatca ctcttgctaa acgccaatcc
    13621 tcatcatctg taaagcgaat cgacattctt ttaaatagtt ggccaagtat atcaaatact
    13681 tcatgaactc tgtttttagg aaagtctgga tgacaaacca cctctgtcag taaatcggct
    13741 ccatgtgcaa aagaatgaac ccaaccatac tgacttgaga aacctgttgt atccttttct
    13801 tttgaaagat agtgcaagcc ttgatttgaa agatcatcac gaatttctga ttgtaatccc
    13861 tgataaaaaa ccgattgctg gttagcatct gcagacaaga gatttgcata aacaagtgcc
    13921 ctaaaagaac gttccagtgt tggcaggcct accttatcaa tctctttatc tagtcctaca
    13981 tcagatgaaa ccccttcagc aatgaaatga aattgctcct gtataaatag ctcttcctga
    14041 atccccttag caaagcttgt aaaaataagg tcatcacgaa tttctggaga aggatttccc
    14101 aaatgatcaa acaaccactg gatttcttcc tggttataat ttggtttttc ttctgctatt
    14161 tttcttagta aatcttgata catggtcaat acctctacat ttctagcaac tgttcaaaaa
    14221 ggcagtctta aatgacctta ccaatttgta aaattaagtt aaaaagaaaa agacatttat
    14281 attcagagaa acagcatatt tctgaaaaga tatataaatg atttattcca tattacaaca
    14341 aataaacttg taatgataga gccttatcac aaaaatcaca ttcctgtctc aaaaattgcg
    14401 aaaaactagt tataataaag tgaaataaaa actatacaaa ttgattaggg aatttaaaac
    14461 aatttctaac aatattttaa aaactgaacc gtactatttc aacttccata aattacaata
    14521 ttgataggca cagttcccat acctgtccaa attcgaataa cgtttagtat aaattagaat
    14581 atgactacaa catcacaaat aattagacta tctataatat ctacgatgta acatatacat
    14641 aggaagcacc gttatcaaga gcgccaaggc tatcaaccag ataagatgaa gatacaaacc
    14701 tgtcacctca cctccccata taatacgaat catgcgagta gcatgataca agggagaaaa
    14761 ccaagtcaaa tcaccaagta ttgggggcaa ggaagtaatg ggaaagaagg tatctgaaaa
    14821 catataaaga ggacggatta ccaaaacatt gtagtaattc agaaattccc tagacggcgc
    14881 caagtaggta aagattagtc ccaaaacacc aaacaaataa cccactataa ataaaatcag
    14941 aggaatcaat aacatcaaga catgaaaatg cgctgtgata agcatggaaa tcagccaaaa
    15001 aatcccaccg aaaatcactg cacgaatacc tgcccagata gcctgaccca ccacaatatc
    15061 actcgtattg attggcgtca tcaacatagc atcataagtc ttttcaatct tatactggat
    15121 aaaggcattg accgttgttt ctgcggtggc cgcagacatg gcagtcgcag caattaaacc
    15181 tgtaatgaca aaatcacggt agagcatacc gttaacatgc gtcaaatagg caccaactcc
    15241 aaatcccatt gctaaaagat aaaagagggg gtcgataagg ttggggacaa ttgaaatttt
    15301 aaataaattt ctaaaactca tgtagttgcg taccacaacg tgtccgatgg actgaaatga
    15361 taacttaaac atgcaagtcc tccttctctg tcccagtcaa ccccaaaaaa agcgtctcaa
    15421 ggttgtcagc atcatacttg atgagcaagt cttctacagt tccttcttct ttgatagtcc
    15481 cttggtggag catcagcacc ctatctgtca aatattcaat ctcattcata tagtgggaag
    15541 taataatgat ggaaacacct aattccttca actccaaaag tttatcccaa ataatattgc
    15601 gggattgaat gtctaaacca actgtcggtt catctaaaat gataatatca ggtcgattga
    15661 tgagagctct tgccaagaca agacgtcgtc gcatcccact cgacagctga ttcaccatct
    15721 tttgcgcatg tttgctcagt tgaacaaaat ccaagagaga atcgattctc ttcctaagtt
    15781 cgacagatga gataccataa catagaccgt gagcaaaaag attatcataa acattcaagg
    15841 tcatgtccag catatcctcc tgccctacaa tacccagaca agatttactc ttacgacgat
    15901 tggtttcaat attttgcccc aagatatcaa tctctcctga ggaaattgag gtcagtgagt
    15961 aaatcatctt taaagtggat gttttgccag caccgttgat tcccaagata cccaaacact
    16021 ctccttatcc caattcaaag ctaattccct tgacagcttc ataagaacca tattgctttt
    16081 ttagattttt aacacttaac ttcttcactc tttctttccc ccacaaatag agcatgttgg
    16141 atactttgtt aattcatctc acttttgaca aaatgttgag aatgtaatct taagattaac
    16201 gtccttcaac tgtggatact gctgcaatta cttttgtaat tttacctcca tttaaactca
    16261 gacaataaaa tttaaaatat tctctagtaa aacattttta aaatctattt ttcttgtgct
    16321 ttaattatag tataataaaa gatagaaaat catcgatata tgaaatttgg agaaaatttt
    16381 tatggaacca gatattttca tcatcacaaa actcttatca gacccttctc ggatgcacat
    16441 tttagatatt ctaatggatg gaaaagctca cacggttaac gaaattgcca gctttaccaa
    16501 aatcaagcaa catactgtca gctatcacct caaattactt accgaagcgc aggtaaccac
    16561 tctacaaacc tatggacgtt ttcattatta ttctttaaaa agtgctgcca ttgcagaaat
    16621 gctggaattt ctcagcttct actctcctca gcgtgatgtc aaaagttata aacaacacat
    16681 tcacaaaaag gaattaaagg tcgctcgcac ctgctatgac catattgctg gtgagcttgg
    16741 catttccatt accaattatc tcttgcaaga aaatctcctc agcgaatcag aaaaagactt
    16801 ccaactcact gaagctggga agtcttattt ccaaagaaaa ttacacattg atacggatga
    16861 attgaaaaag aaaaaacgga aattttgccc taaatgtttg gattggagcg aacgtaaaaa
    16921 tcatgtcggc ggagctctcg gcaatgctct tttagaattt ttcagtgaaa aacaattggt
    16981 catccctgca caaacgccac gttcacttac cattacagag aagggcaaag aattcctcga
    17041 aaaggaatgg gggatttaaa catggacttt taagcaaata actgtccata cccattctat
    17101 aacaacctct ctatcccctt actcccccaa ctcagcactg taggcgataa tctggtcaac
    17161 tgtgtcagac aagaattgga tggtatcacg gagtggtttg tctgttgaaa tatcagcacc
    17221 gataatcatg gctgactcaa gtggtgtctt gctaccacct gatttgagga gattgagcca
    17281 gtcttcagct ccagtttctg agtttttaag atgaaggtaa ccagctgtcg agatgacaag
    17341 accagcagag taagtgtaac tatacaagcc catatagtag tgagcttggc gcatccaagt
    17401 caaagctgca tcgtcgtcga tttcaatggc atcgccccaa aaatctgtca aaacttcctt
    17461 cataatgctg ttgagtttgc ttgctccgaa ggtttctcct tcttcaatca atgtatacac
    17521 cttacgctgg aaggcggctt ccaagaggtg ggtgataaag ttatggaagt aggtgtctgt
    17581 caagcgatga gccagagcga agcgtttttg acgtgggtca ttagattggt tctctaagta
    17641 atcactgagt agcaattcat tgaaggtcga cggtgcttca acataatagg tcgacatgtg
    17701 ggcgttgaaa tagctttggt gattgtctga aaagatgaat tgaccagaat gcccgatttc
    17761 atgaatcaag gtatagacat cgctcaaacg gcctgtccag ctcatgagta cataagggtg
    17821 tacgcgatat gggtccgccg cataaccacc ggaatccttg ccactgttag cagcaaagtc
    17881 cacccagcgc tcttcttgat aacgagcaac ttcctgacaa tattcttgcc ccaaaggttc
    17941 taccgacttc atgaccaaat cataggcatc gtcaatagtc acttcaggat tgagggcgct
    18001 gtccaagtcc aatttccagt ctgcaaaggt catcttttca agaccattta ccttggcaac
    18061 atgcttgagg tatctctgag cgactggtgc aaagtccttc atgatgaggt caatctggcg
    18121 gtcaaacatg acacggtcca cttcttgttc agctagaaga tagtcaaaga cagagtcgta
    18181 tcccttcata tcagccaaga gtttttcaga cttgacctga gccagatagg ctgctgcagc
    18241 cgtattttgg tgcttacgaa gtccctctga gaaggaacgg aaggatttct cacgaacctc
    18301 agcatcctcg tgattttggt agaaattctc ataggtgaca aagctgtttt tataggtctt
    18361 gccatgggct tcaaagtcag ccatttcaaa atccccagct cgcatcttag tataaatgtc
    18421 ctgcggacta tagaaaactt caccgagatt ggtcaaggcc ttctccacat cagcccctag
    18481 atagtgggct tttttgattt tggcctgacg aatagctgcc gtcaagtgag gcaattcacc
    18541 caaacggtcc aagacttcct cgtctgctac caccaaggca tcgtcaaaga aggtcaaggc
    18601 tacgctggca tctgtttcaa attccatccc agcttgggca atattggcaa attcgtcatt
    18661 gctatagtcc gtcgtctgag gcataaaagc atagttgcca atatggctca tctgaatgta
    18721 gatctgttcc aattccgcaa aggccttctc gaaatcctca aaagtgtgaa gattgccctt
    18781 gtaatcacgg ctaaactggt tgatgtcttc acgagctttc tcgattgcac gcaagaaatc
    18841 ctcacggtct tggtataggg ctgttaaatc ccagagttcc ttctctggaa attctgaacg
    18901 gtgtttttgt tccattttct tcctcttatt tctctaattc tactaaaaca ctaagggctg
    18961 ataaggcgta aagcggtgct gtttctgctc gcaaaatacg aggacctagg cctgccaaaa
    19021 ctgctccttt agcttcaaaa ctttcgattt ctgcaggtga cagaccacct tctggaccaa
    19081 agataaagag cagtttggct cctgtttcaa gaccagtgac tgcttgcaga agcgcagcgg
    19141 cttctccttc tttagctgat tcttcatagg ctactatgat agagtcaaac tggtccagct
    19201 gagctagaaa atctgctttt ttctcgaaaa gtttaatact tggtacaata ttacgcttgc
    19261 tttgctcggc tgctccaagg gcaatttttt ctagtttttc aactttttta cccaatttct
    19321 tgccatccca cttggcaact gaccagtctg caggaaaggc ccagatttgg ctagcaccca
    19381 gttcggttac tttttgagcg atgaactcca gcttgtctcc cttgggaaat ccagatgcga
    19441 tggtcacttg gactggtagt tccacattgt catttaattc ttggaccaac tcaaactgac
    19501 gattttccat atccagcacg cgcgccaagc gcttgatgcc atcatcaaag actaaggtaa
    19561 cctcatcctc ttctttcaag cgcataacct gaaacatatg cttactggtt tccttgtcct
    19621 cgatagtgac aggagagata gcactgcctt ttacaaaata ctgctgcatg ctagcctcca
    19681 atcacaccag agatatcctt ggttttctta aagacacagg tattccattc cccttgaacc
    19741 atgtgagttt cgaggaaaaa tccagctgac tcagccgact ggcgcaccat gtcccacttg
    19801 tccttgataa tgccactcat gatcaggtag ccttcatcct ttaccaagcg ataagcatcc
    19861 tccgtcagat gaatgagaat atccgccaag atattagcca cgatgacatc tgcctcaatt
    19921 tccacaccct taagcaaatc tccagccgct acatggatat tttccatgcc agggttgagc
    19981 tcaatatttt cctgagccac acgaaccgcc acatcatcca ggtcataggc gaaaatttct
    20041 ttagccccca gaagcgagct ggcaatagag agaacccctg aaccagtccc cacatctagc
    20101 accgtttcgc caccacgaag aacctgttcc aaggcaaaaa ggctcatctt ggtagttggg
    20161 tgggttccag taccaaaagc catgccagga tccagcttga taattttttc tcccgcagtc
    20221 gcctcatagt ctgtccaaga gggaacgatg gtcaaatcat gagtgatacg agctggctca
    20281 tagtatttct tccagttatc tgcccagtct tcctcagcca aggcagtcgt acctattttt
    20341 aactctccca aatccataaa atccgtcaat tctgatatgc gagcctgcaa gtccgcctca
    20401 accactgtca catccaccgt gtcagggtag taggctgtca ctacgatttc ttcttgctgc
    20461 tcgacctctg ggaaaatctc gccgaagcgg tcaacatttc ccacatagtc cagactgtct
    20521 tcaatcgcaa caccttgcgc tcccagctca atcaagagat tggaaaccaa ctcctctccc
    20581 tcacgcttca ctgtaacttt taactcttgc catgtttcca ttatgtattt tgcttacctt
    20641 tccatcagat taaaaatagt ctttccaata acaacaataa ggttatctct taatttcttc
    20701 tctaactcta aatcaattcc actattttgt atgaatttgt cttctacatt tctatataag
    20761 cgttttactc tagtggggtt tcctgcatca aaatgaggta cataatggta aattatgaca
    20821 ggaacagaac ttctgattga ttgttcagca atctgattcc agatataccc atcagtctct
    20881 cccaaagaaa ccccataaag aattatgatg tcagaatttt ttataatatc gctattttta
    20941 acatccatat tttctctata gttcttcaaa actaaatttt ttattaagga ttctttttgt
    21001 tcttcatcaa aactatttga aatctgtgtc tcgtcactaa ctcctaaaac tgtgcaaata
    21061 tctaccgttc catgtgcatg aattggaggc gcaatgtgaa atttataatt attagttcgt
    21121 aattgattgc taaatgattt tgctgactca ttatataatt tatcgattac atttgtgtaa
    21181 ttaagagtta atatattcac gatatcgtgt tgatatagat tttcattata ttttttatcg
    21241 atagcaggtt gattaattac agggagagag gtcctcatat tatctagagt gcttataaag
    21301 tcaattgcat tacctttctc aagatttttt tcttgttgta tgcgtagata ttctcttaaa
    21361 tcatcaacta cttcactaaa atcatctata aatttctcct ttatttctat acttgaggag
    21421 atgaggtcgt tatcttttgt taatttacca attgacaatt caaaatctga ccaattttca
    21481 taatcattta ctttatcaga aaatagagac tcataaatga aatttgaata tttttcctcg
    21541 ttctctgtcc tacttatata aaccttattt tggaattcgt agaaatccct atatcttgtt
    21601 ttcaaaccat attgcaaatc caaaccattt ccaactatat aagtaatatt catatctttg
    21661 ccctcttgtg ttcctaagat ctaaaataag gataaaatat ccactattca aattcaattt
    21721 cttcatttaa actattaaag aggtctactt gagcttctac ttgcaatcta ttaactagcc
    21781 aaccgcgtaa ttcagcttgc tgaataaaat cttcaatacg attaacccca tttaattctt
    21841 ttaatgtaac tactacacca aaacgtactc cttgtccatc accgcttttc aaacgttcga
    21901 ttgttttaat actcatcccc cactgaggat tagatggatt taaaattgct ttagctctct
    21961 ttcgagaagt aaacgactct ccaatatgct tgacattatc ccatttccta aatatatttc
    22021 tagcagcatt ttctctcaca tatcctgggg aatcttcggc atgctggttg tctttattta
    22081 tcgatttgat accgtctgac tttaacctac caaaagtaag ctgcatctca gtatttgtat
    22141 aatcaacccc ttgttttctt gagcagttag ggaaataaca cattgttgct ttagctacat
    22201 atggataact ctcactagaa ataggtactg gaaaatcata attataggta tcataagccc
    22261 tagagatatc tgacacaata aatttaattt catcatcagg tgtagataaa atatcatcca
    22321 tttttattgg aacaatacca tttcctatca aagataaatc agtgaatgtt ttcttatcat
    22381 tccagggtat tgctgcatca attagcaaag ccttcgcttc ttctcggcta agtcccataa
    22441 tatgaatgag ataggccatt ttccttgcaa taaaaggtgc cgcaaaactt gttccagcta
    22501 cacgacctaa tcctagaggt tcacaaacat ttataaagtc accatttcct cctccataat
    22561 atgacacatc tggtttaaca aagaatgata aaacaatacc ctctcgtgaa tatgacactg
    22621 attgattatt aaaatcaaca gaatttacta ttatagaatt aagtgaatca gcaggagcac
    22681 ctattctttt gcgtttccca tttattactg aagcatttgt cccagctatg ataaaaatta
    22741 catcattctc aaattgaatt tcgtctaata atgctccctc tgcagagata aaattttctc
    22801 ttatttcatc attggaccct aaagaaagat tccaaacctt aatatcagca ttctgagaaa
    22861 caatctcttt tatctgtttt atgattgtaa atgaattaaa tccactttgt agtgacacac
    22921 caaaatgcct cactctaaaa tttccacaac catcatccag attagggttc aaattggctc
    22981 catcaacgat taaagaagtc acagctgtcc catgcttgta atcttggcta tctttgctaa
    23041 tatcaggtga gacaaaatca tgatattcta cccactcatt aaagtaaact cttttgtcaa
    23101 ataaggtatc aataacgcca acaactggtt cgttcattgg agatggaaga tttattttta
    23161 aatcattatt atctaaagaa aaatcatcta cagataactt agaaaaatct tccacaatca
    23221 tggagacaag atagggcgct tttgatagta gtaattcaat atttttttca tcaagcaaga
    23281 ccgtggtctg attcatgata ttagcttctg aaatatcaat atttaattta ttcagtaatc
    23341 taaaaatgtc tgtatggaca tcataaaatg tcacgataga attttgaata tcagaaacag
    23401 tagtgtgctc aactccaaaa ttctcaataa agcaagaatc tctcaaatac tgttgaaatt
    23461 tgctttttga aataccatac tccgaaaaat ttatagaagc aaacgttgat gaatcagaaa
    23521 acatctcaca tgttatcgct ctatcaaaat gttcctcaaa aacttcaatt atcttactta
    23581 aaacggttat tgttttatta agagcatctc tagaaatata atgagtaaca atatgttttg
    23641 tcttctcatc attgaatttt gctcccacaa tagtatcatt agggaatgga ttccctcctc
    23701 ctacattgaa atagccatta atacggttac ttttggcaac aattcgatta tagtaaatac
    23761 tgatcaaaat accatcgata atgttatttt tctcccaata tgttttcgtc tcttctaatg
    23821 aaaaatgaag atacttcaaa tgttccaatg taattattgt ttttttgggt atagttattg
    23881 gtcccatacc attatttctt gatttttgtg taaagctttt acctcgtaat gtcaataatg
    23941 tattcatttt aatcctcgct taactctcgt gatacactac tcttagaaac acctgtcaaa
    24001 atctcaattt ctctaacagt aaaacctagc ttcgataatt tagaaataga taaatttcta
    24061 ccattatgca aacttcttag caggcgtttt tggtaatcat gcggatctga tggatcacta
    24121 aatgccaatg acgttcttat tgagtttctc aaatcaccag gattcggtat tacattggca
    24181 ctattgataa tttttttaaa taattttaaa tctctagcta cattcttaaa ttgctttaat
    24241 aactcattta aaataatagt agctacttct actttatctt catcagtata acggtcaaag
    24301 tcaattatgg catcgaatct tctcgtaact gctttatcaa gattttcaaa aagatttgtt
    24361 gttgcaatta atacaatttc tggtgacagc ctatccaact cctttaaaaa ggcagaagtc
    24421 actcgtccca tttctcttaa atcattctga ttaaccctat ccaacactat ggaatcaatt
    24481 tcatcaaata ggatgatata attttgcttg aaaggaagat tattgatttc attaaaaaga
    24541 gttgctaagt ttttgactgt ttgccctagc ttactatcta ctaagtgact gaaatctact
    24601 acaagtaatt ccttgccaat aagtctagcc acctgcttta cactttcagt ttttccagta
    24661 cctggagatc ccacaaataa aaatttattt attccaatat gatgattgac agcgtttatt
    24721 attcctttta aatcattcat aattgaaaga ggcaatggga gaggaccaat atctagttta
    24781 gcaggagtca aatactcact aggattttct atttgtggca tgaatctatc actttgagac
    24841 attaacccca taatatattg tgctatttgt gtatcaccat gtttattgaa gttccgagca
    24901 attgctatgg attgatttct aaattctgtc tctctgccct cataatgata ctttattaaa
    24961 tcaagaacat ctgatttttt catgattcat tcctccttat acaaataata ctataatttc
    25021 gggacaaagt caattatttt gggacaaaat taaaaaagaa taaccttgaa aggatattct
    25081 tttaatgcaa aactatatca gattttccct gacactcttt cccccacctg gcagttccca
    25141 catattggcc cagggaatgc ttgccttatc atcgcgtaag atagtcaaaa gcttatcccc
    25201 acaaaacaaa gcaatcttac agcctgggaa atcagaaatt tctagttcca tcttcagttc
    25261 cttctaacat ttccttttcc agctctgcta acaagttttc ataatagcgt ttctcgtccc
    25321 tcaacattcg actactatcc attttctgtc tagcaatctt catagccttg tgagtttgaa
    25381 ccacatcttt ccttacctta aattgatacc aggcttgtat cacttgaaga ttggacagtt
    25441 tgagagacag aaacgatttg acctgtcgaa tactagcata ttgctccgct tgctcaaaat
    25501 ctccttccaa caaggcgata tgaagcaggg atagttgggc aactgtctgc atcatcggag
    25561 tagttgtcct ctcaagtaat gcttgaaact gctgtttagc tacttcttcc ttcccttcca
    25621 aaatggaaac ttcaccttgc atacctaata caccatccgc aaaactccct cgtgcatcct
    25681 caggaactgc ttgaacaaag tctttcaaat catattcttg aggagccagc aaagtttgag
    25741 cagaatgtct caataccagg taggcgtatt tggtattttc agggtgttgt agtaattccc
    25801 aaatttttgc tccatcggtg atgtcgactg gcaaaatgtt atttaggaag aaagataaat
    25861 taagaaaaat ccaagtccct gcaaaatacc agcttcttgt caaaaatcca aacactatcg
    25921 ccaataatat caagccgaga tgaaccatca agcctcctga aagcatcagg atgattcttt
    25981 gatcgctttc atcctctttt aaaccaatgt attgagcacc aacatttttc agaatggctg
    26041 ttctactaag atgaaacctg cctgactttt tggtcaaaat aaaatgtcct aatccaaaag
    26101 ccaccagccg atagcctgtc aagtagccac aaaaagcatg acccagctca tgaagaataa
    26161 agattaaata catgcttaga agagcgaagg cataaccaaa agtaaaggct aaaactgcgg
    26221 aataccccaa ctctgcaaat gcgattgttc cacaagcaaa agctagcata ataaagacaa
    26281 cagctaacac ataaaccaaa taagtcccaa ttttcttcat aacacctcca accaactcct
    26341 agtatcttgg ataaggataa aattctccct cttccaagcc aacttttcct tcttcaaaga
    26401 cttcttgatt ccattccata acaaattcct ctgcttctgg atcttccaaa aagtccatga
    26461 gggtatctag tccaacctca gcagtatctt taaggaaaag ggcaaaataa gctaaaaatt
    26521 cacgggaaaa tcctttttta ggcaggtaag gaataacagt caaatagtct tcctcattga
    26581 ctgttgactt ggcaggattg tagaaaagga ccgcttcctc aaaaagaatg tcatctgata
    26641 aaacctctcc gtcttcatcc accatctcca cacctgcagc attttgcgct tccaatagaa
    26701 aactcacttc taccgcgtgg ttacgcttgt cccaactaat ctcaaagtca aagggaaagt
    26761 tcttgtccaa ctcttcctct aaaatatcta aaaatccgta tgttgccatt ttgtcctctt
    26821 tctatgcgac tctttaatcg ccccgattgc tcggaaatat gctaaaatag atactaccat
    26881 cttaccacaa aattatttta tgtcctaatt ataccatatt acctcattta aacccttggt
    26941 atcaatgatt ttcttaaaag tctgatttct tcatttctca taaaaatcaa tataaaaagc
    27001 cctcgaaagg gctaataaat ctataaaatc aataggcgag taactagcac aagtggacgt
    27061 gcttttttat tgactattac cacgatacca cgcttaatct taggcttgaa ctttcttatc
    27121 tgcaatagcg tctgtcaaag tctgagaaaa gttaagtccc atttctcgtc ccaacttatc
    27181 tgcccatttt ggtatggtca aagtcttttt aatgggttcc tgacttccta ggtattctga
    27241 tacatcaaca gataccatag aaataaaaga tttatcaagg tcataggttg acacgaaatc
    27301 ttcatcatct ttaaaaggat cattatcaat taaagacaag ctattgatat ctgatggctg
    27361 aggtaactct ccatcactct ctatcaaatc tgcaacagtt atccctagcc actccgaccc
    27421 catagccaaa gcctcagaaa tcccctctcc ttgtgtagct gagtattcaa aatctgggaa
    27481 atggacaaaa taagtcgctt ctgttccgtc tgtgtcgtca taataaaata aagctggata
    27541 cgtaactaac atttcactac ctccatatca aaaagcaggg actgaatttt acaacccagc
    27601 ttgctttcct atccctcttt cagtgtactt attcagctca ccatgaagga ttgtgatagg
    27661 tctttcccct tgcttttcca ttttaatatg ggagccttta ccgcctctag tctttatcca
    27721 accatgggcc gtaaggagtt taaccatctc tttttgtgtc ataggtatag cgcttttacc
    27781 tcctgacaac accattacaa cacgtgttac acgtattgta aaggagtgat acttattatt
    27841 ctattataca taaaagcccc tagatgtggt tctaagggaa accaatttat tcagacctat
    27901 ttttctaatg agtagtaaaa actgcttctt tatcgagcaa ttcatcatct gtatagtcaa
    27961 ttgtaaaagt atctcgatct aagacagatt gaggcggagt tgaatgaatc ataggaccac
    28021 tgcgtactct atatttttta tctccaattt ttacaaactg atactcttcg aaaatcaaat
    28081 tcaaaccacg tcaacgtcgc cttaccgtac tcaagtacag cctgcggcta gtttcctagt
    28141 ttgctctttg attttcattg agtatgatta actctcaagt cttcgaaatc aggattttca
    28201 acagttatta caaggaggcg atttactact tcaaaaacat caattattct atttttcata
    28261 ttttttcaac ccattattag aatgaacttc ttggtaagca aaatcaagtt tagatttaat
    28321 gttttcgtac aaatctaaaa tctcttttgg agtatcttcc cggaagaaaa gttttctttt
    28381 ccctgaaata acttgatcac taagaatcca atgacgaatt tgttttgtaa aaatcaaaat
    28441 ttcctgactt ggtccatcat ttccattgct tatcacctct cttttcatta tagttcatac
    28501 aatgacattc agcaatatta tttctcaagt cagcacttcc acttctttag gctcaactat
    28561 cctattttga gctttaagga aaatcaaatc tctcatgctg atacctctcc tcattaaatt
    28621 aaatagtaaa aaagattcta tctcactccc tgattattac aaaaccattg aaatatcaca
    28681 actaataggc tagaatggac atagtaagat atagtagatg agtcattcta ctcaaatcca
    28741 cgttagaaag gactgctatg ccagacaatc tcgcgcttcg catgcgccct aaaaccatcg
    28801 accaggtcat cggtcaggag catctggtcg gacctggaaa aatcatccgc cgcatggtgg
    28861 aagccaaccg cctgtcctcc atgattctat atggccctcc gggaatcggc aaaaccagta
    28921 ttgcctctgc catcgctgga acgaccaagt atgcctttcg aactttcaat gcgacagttg
    28981 atagtaaaaa gcgactgcaa gaaatctcgg aagaagctaa attttctggt ggtctcgtcc
    29041 tattgctaga cgaaattcat cgactagata agaccaagca agacttcctc ttgcctctct
    29101 tggaaagtgg actggtcatc atgattggag caacgactga aaatcctttc ttctctgtca
    29161 ctcctgccat tcgtagccgt gttcaaattt tcgagttgga acctctgtct aaccaagacg
    29221 tcaaagaggc cctgcagata gctctaagta accctgaacg tggttttgat tttccaatag
    29281 aactagatga ggatgcgctg gatttcatcg caacctctac aaacggagac cttcgctctg
    29341 cctttaactc actggacttg gctgttctct ctacccctga gaatgacgag ggcattcgcc
    29401 acatcacctt agacatcatg gaaaatagtc ttcagagaag ctacatcact atggacaagg
    29461 atggagacgg tcactatgat gttctatctg ccctgcaaaa gtctatccgt ggctcagatg
    29521 tggatgccag tctccactat gctgcccgct tgattgaggc tggggatctg cctagtctcg
    29581 ctcgtcgctt gactgttatc gcctatgaag atatcggctt agccaatcct gaggcccaga
    29641 ttcataccgt gactgctctg gatgctgccc agaagattgg gttcccagaa gcccgcattc
    29701 tcattgccaa tgtcgtgatt gatttggccc tttctccaaa atccaactca gcctatgtag
    29761 ctatggataa ggcacttgct gacctcaaaa catcagggca cttgcctatt ccgcgacacc
    29821 tacgtgatgg gcactacagt ggaagcaagg aactggggaa tgcccaagac tatctctatc
    29881 cacacaacta tcctggaaat tgggtaaagc aagactatct gccagaaaaa attcgtaatc
    29941 atcactattt ccaagcagaa gatactggta aatatgaacg ggctttggct caaagaaagg
    30001 aagctatcga ccatttgcga aaaatctgaa atccttttca aaaaattgca ctttcctctt
    30061 gatttttttt aaaaaagtgg tatcatataa atatagaaac gctgtggtgt acgacttcac
    30121 acttaagtgt tgaccgacta ttttttgtat tattagggaa acaaaagtct tctaacagca
    30181 tgtaggccgt ctcacacgga aacagcttca gttagagcga gttgcccacc tgcttaattg
    30241 cgcgggttca atacaaaccg tgaagtttcg gcaccaatac agcttttttc tttgcctcct
    30301 tagctcagct ggcagagcag cggactctta atccgtgggt cacaggttcg atccctgtag
    30361 ggggcatata aatacaacag gaaaagcctt ggaaccaagg tttttttgct taaataaaat
    30421 ttttttcaaa ttctttagaa aactagctta aatcataatc caacaccaat tttacaaata
    30481 ccataaacta agcttatata cccaaaacac aaaaagtcct ctttccacta ttttagaaag
    30541 agaacttttt ctttaggaga aataacttaa tttttaatca attcgtgata gctcagctgg
    30601 caccgttaag taataagttg cagtcaagct tgcttcacct tgattgacaa aaatctcgat
    30661 ggaattttta tctagaacaa cttccaattc tttagcttca atatctacat accgtcgact
    30721 agtgtcctgt tcttcttcac ctagaatttt ttgaataaga tggctacgat caatgtaaac
    30781 ttgctgcgca ttactgtcat aaccaaattc aagataatct gtatcatttc ctaagtggta
    30841 atgacaatct ttatctattt ggatttgata ttggcctttt ttaacaggga attgtcttag
    30901 tttgccatct tccaatctta gaattctagg taaagtcatg gcacatgccc atttgtgttc
    30961 ttggtcatgg gttggaaggg tacgccccca tgtctgcatc caagcaatca ggatacgacg
    31021 attttgatcg tccaacaatg tttgaggcgc atagaagtct tggccatgat caatttcttg
    31081 aactgattct gggataaaac gtttttctct ccaatctacc ttacccgtga acaaaagcga
    31141 tgagttgatg ttatgatatg agtctccctc acgctgataa cgcatgggtg acataataag
    31201 gcaatctttc ccatctaact cgaagtaatc tgggcattcc cacataaagc cttggtgttc
    31261 tccccctttt aaaaagatgg attcgaactg ccattctact aggttatcgg accctagtag
    31321 aacgatacag cccacattat ccatgtgttt ggcagctact acggagtaat agcgtccatc
    31381 tttttcaaag agttttggat cacggaaatc agcagcaatc aactcatctg gcaagtctgt
    31441 tccagttaca actggatttt gggaaatctt ttcaaagtga atcccgtcat ctgaaaatgc
    31501 catattttgc acttggcgga caccggtttt ttcttcgata tgcccagtgt acatgagcca
    31561 gaggcgatca tccttgacaa tggcagagcc tgagaaacaa ccatttcggt cataatcttg
    31621 gtcaggagca agtgccactg gcaagtgctc ccaagtcacc aagtccttac ttttagcatg
    31681 tccccagtgc ataggtcccc aaacactatc atatggatag aattgataaa agagatggta
    31741 ttctccacga aaataaacaa atccatttgg atcattgatc caaccaatct cagctgaaaa
    31801 atgttcttca ggcttatatt gagtattaac gagatgttta ttttctgcta taaaacgatt
    31861 ggctttttct actgtgtatt tcttatctcc cataatcaac ctctagtttt tgtttgcttg
    31921 gtattggtcg tagtattttt gtttaatagc gaggtaatca gaaagtccgt atttttcaag
    31981 ttctttcttg taatcatccc actcagtatc aatattgcca tttacaatcc attcagcacg
    32041 tttacggtag atatagtcat tcatatctgc ctcgatatgg gcaatcttgt ccaaatcttc
    32101 ctgtgtcata aagactcttg gatagttatt gtcattgctc atgtaaggaa cataatattc
    32161 tttgataaga tccaaacgcc atttggcatc atctggcatg gttgtcactt taccatagta
    32221 tgaatctaga atagctagtg gtcctcctac ttcagtcttt tgacgaagtt ctgctggtgc
    32281 agttccgttt agtggtaagt gttttagact atttgacgct tgatccaatt caaagatgtt
    32341 ttgttgtttg tcatctccat aagttcccca gttattttgc acagattgga gtggagcgta
    32401 ttgtgcatca atccatttag ctgtcaattc taggtttttg tttacactgg taataaccat
    32461 cttgtcacgt gcaaatccca taccgtttgt acgagctacg tgtttttgac cacttggtcc
    32521 agcaagtact ggtaaaacat cataactttc gttacttcca gtaacattat tcttatccca
    32581 tgtaaagtaa acaccaaatt tctgatcatg acctttagca atgtaactat tccaatcatg
    32641 ttcgaaagct tctttatcaa tcaagccttt ttcttgcaat tgacggataa atttgacacc
    32701 ttctttatag ttatcgttat ctgctgtgaa gtcaactttg ccatcatttc ctactactaa
    32761 atgatcatcg ttatccccta taccaaatgc agcaaatagg aatttaaaat cttcgtttcc
    32821 gttaccacta ataaatgtaa atggaatttc atcagcctct ccatttccat ttggatcccc
    32881 gtttttgaaa gcttctagga ctttaatcaa atcatcagta gtttttggca tttcaagacc
    32941 aagtttctta agccaatctt tgttaatcca agccatatcg ttgacgctgt gaatagactc
    33001 tttaccatct ccaagctctt caatccatgg gaatgagtaa atgtgcccat caggtgctgt
    33061 catcaaggcc ttgtactctg gtttctcatc caaaattttc ttaagatttg gcatgtattt
    33121 atcaatcaaa tcttcaactg gaataataac acctttttta gcccagttca tcaagtccac
    33181 atctgaagct ccgtcgttgt ggatagcatc tggtaaatca ccactagaaa tatccaagtt
    33241 acgtttttct gcaaagtcgg attggtagtt ggtccagtca atatgaacgc cagtttcctt
    33301 ctccaaacgt tgtaaaatta acttttcatt tgggtcttta ggagataacg gtgaactggc
    33361 tgtcataaac ttcaatgttt tcttttcttg aagcgggaat gttacacctt ccaacttata
    33421 atctggactt gaagctgtat tttttgagcc acaggctgca agtactgcta aactagctgt
    33481 caacaaaact gctgattttg agaatgtttt gaatttcatg agaaaactcc ttttattttt
    33541 tcttttttta tcctttaagt gaaccagcca taattccttt atcaaagtat ttttggaaga
    33601 atggatacat aacaatcaat ggcaagctgg aaatgacaat agttgcgtat ttaatcaatt
    33661 cagctaaacg tttcatttca ttcatagccg cttgtgctcc aatcatgtct tgacctggtt
    33721 ggctctgaat gagaatttta cgaagtacaa gttgcaatgg ttccaagttt ggatccttga
    33781 tataaatcat tgcatcaaag tatgagttcc actgtcctac aaaagcatag aggaagagaa
    33841 caaacataat tggttttgca agaggaagca tgattttgaa gaaaatctgt aaatcatttg
    33901 caccatcaat gacagcagct tcaactaatt cttcaggcaa tccttggaaa taggccctag
    33961 caagaataat attccaaaca ttgacagcac ctggaacaat gattgcccat ggagtattga
    34021 gcattcccaa ttcttttacg agcaagtaag ttgggactaa accaccacca aagaacatag
    34081 ttacaatcaa gaagtagtta atccaacgac gtccaaccaa gtctttctta gaaagaggat
    34141 aagctgtaaa cacagatagc aagactgtta aagctgcaaa tccaaaagag tatagtagag
    34201 aattgataaa acctcttaga atagattggt cactgaatac acgctgataa ccttctacag
    34261 tccaatcggc tggattaaag ctaatccctc tactaaccag aaccttagga tccataaagg
    34321 atgctacgac gatataaagt aaaggaagca aagtcatcaa aacgataaag acaataatga
    34381 ttttatttaa gagtaagata cgtctatcaa attttgtatc cataatcgaa tttttcatac
    34441 ttccctcctt aaattccttc accattattc atgcgtttaa cgatttggtt aactgcaaca
    34501 agcaatacta cgttaatcac tgcattaaac aaaccaaccg ctgttgagta agaatagtct
    34561 cctgatacaa gaccaacttt atagacatat gtcgagataa tttcagaagt tggcaaattt
    34621 aacgatgtct gcatcaagaa tgctttttca tatccgacat tcataattcc acctgcagct
    34681 aaaacaaatt ggataaccat aataggctta agagctggaa tatcaatgtg ccagattcgt
    34741 tggaagatat tggctccatc cagtcgggct gcttctacta aggctggatc tacatttacc
    34801 aatgttgccg tgtagagcgt tgaagcccag cccattcctt gccagatacc actaaagatg
    34861 tataagggtc taaagaagtc tggatttgtc aagaagtcag ccttcattcc aaacatagaa
    34921 agaaaattgt tgattggtcc tcccactgaa aagaagagga aaatcatacc gacaataaca
    34981 acgactgaga taaagtttgg tgcgtataaa atgagctgaa ttcgtttttt gactttttca
    35041 ctcaagagtt gattgagcat aatagcaaga atgattggtg gtaaaaagcc aagcaataaa
    35101 ccatagatac ttaattttaa tgtgttggct aacaagatac caaagttggg agaggatatg
    35161 aattttgtaa actcagaaaa accaatccaa tcactcccta aaattccttt taaaggattg
    35221 taatctttaa atgcgattaa aaccccatac atagggatgt atttaaagat aaaggttaaa
    35281 actaaaccgg ggacagtcat caataacaag agtttttgtt tcttgattct ttcccaaaga
    35341 gaaacttgct tcgctttgct attcatagca acctcctttt tgaaacgttt catttttttc
    35401 tagaaaagat agcgcttggc gctgtctctt tatttctttt ttgaaacgtt tcatttttgt
    35461 tttaaaaata aatctttttt atctgaattc attctatcat tgatagcgct ttctgtcaag
    35521 acttattttc attttttgtt gtttttcctt caacaaattt tactggtagg attgtctgca
    35581 aattaacagt ctttccatca attatatcaa acaaaatacg aaccgcttct tttgccattt
    35641 cttccaatgg ttgttcaata gttgaaagta gataatctct atctccagcc attttaattc
    35701 catcgtatcc aataatttgg acatcatgag gaatacgttt accatttttt tctagtattt
    35761 caatcacatc caaagctgta aaatcgttga ttgtaaaaat tccatctata gaagaatttt
    35821 cttccaagaa actctctagc tttccataat agtcagtaac tgtctcatcc aaatcaaaaa
    35881 tactaagagg tattttatgc tcttggacat acttttcaaa tgaaattcta cgacgtttgg
    35941 tttcattaat ggttgtatta tgtccgccca caaaggctaa atgctgacat cctttactaa
    36001 ttaattgttt agctgcttct cttccacctg catcattatc tgatgaaaca caaggaatgg
    36061 caatatctga gtatgtgcgg tcaatactaa caaagggaat tcctgacgtc aagtaatgtt
    36121 caattggact ataggtaatg gcaaccactc catcaacttt attatgacgc aacatctcca
    36181 gatagtcttg ctctctattt gtaccattga tagaacataa gagtaatttg ttatttctct
    36241 tatagacttc attttccaca tgcatagcaa attctgaaaa gaagggatgc cagatacttg
    36301 gtacaatgat tgcaatcgtt tctgttcgat tttttttcat tcctctagcg tagtaatctg
    36361 gaatgtaatt caaagtttta atcgcttgtt ccactttttt caaagttact tctttaatgc
    36421 ctttttcttt attaattaca cgtgaaacag ttccaacact aactcctgct tctaaagcaa
    36481 catctttcat ggtaattgat tttctttgtt ctaccatatt atcacctcct ttcaatatat
    36541 agtatcatgc aaatgctttt taagcaacta tttctcagtc atttttggcc agatcattta
    36601 tcccatcatg aataaaatca ctccaattag cttttgaaaa tacttcaatt ttcatgtgta
    36661 aacatctaca taaaacagga aaagccttgg tttcatagct tttttcgtat cttctacaaa
    36721 aaaacaagag ttttagaggg ctataaatct agatgtacat tttgcttaaa tgattgaagg
    36781 tcttttctta acaaaaacac cccaaaaatt agattttttc tgtctaactt ttgaggtaca
    36841 gttcaaacgc gaaatagcgt ttttttgtta tttttggtta ctcatctaat cgaataaaca
    36901 tcatggcatt taacaaatat atgagtgaga ccgtgtttat attatttgaa tagatgagtc
    36961 tcttattttc aataggagga ataataaaat tggaaataat gatatcataa ggtgaatctt
    37021 ctaaagattc ctttgataat tctaattcgg tccaaacttc cagttcaaaa ttattgctac
    37081 agtaataaga aagtgtctct gcaacgaatt ttgcatgata ctgatcaaaa ttactcataa
    37141 ccaaaacctt tagtttaggc tgattttgta gcaaattaat caccaaatgt ttggtatgag
    37201 tgatgaaggt ataagataga tgatttacca tcattgaact agaacaaacc tcaagagtct
    37261 ctaaatagtg agaaatctct ttttttatat ctgaaacaaa ttttggaaaa atattttgaa
    37321 agttcctgat tgtattccct ttttgatcaa ataaaataaa ctcagtaaac aactcttgac
    37381 gatacagatg tgcggtatta tgcagatgcc aaatcagatt atccttattc tccatttcaa
    37441 tctgatactt gactgaaatc tgatcaataa aatcactcaa tagatggtaa gatttttcaa
    37501 cataactatc cttttttacg catttcataa agagactttc atctatgaaa aacatttttt
    37561 gaaagtaaga cacaaataat tggcaaacaa cttcttcatc taaagagata ttgtattctg
    37621 attcaaaact ctgagcaaca ccttctattc cttctgcctg cattaaaaaa tccaaacttt
    37681 ggtcgttaaa agaatcttta tctacttcca taaaatgacc aaactttatt ctatataggt
    37741 tcgtaactag gagcaacttt agcattctat gcgttgacaa attcattgga aagcttgttt
    37801 ccttataaac caattctaac aattgagata gtggctctga tgaaaaattt tcaaatggcc
    37861 attctaggaa ataatatttt tctgaaaaat attgtgcaaa aaagtaacga atgtctctct
    37921 catttccaat gatttgaaca ggggtcagac tgacttcaaa ttgaaattgc cttttaatca
    37981 ctttattgat ttggctaata atacgataga gcgaagatga actgatataa aattctttac
    38041 aaatactctc agcttgacaa ccttcattaa agaagatgaa ttctaaaatc gaaaaatgag
    38101 ttgaatgttt aaagaaatga tggtaaacca tttcaatatc actatcatcg gtattaataa
    38161 tgcgtatacc attagtagaa gaatgaaaaa tcaagtcagg aaaagcagat ttaacatggg
    38221 atagatcatc tttgactgca cgttctgtac aatttaataa ctctgctagt tcagaacgat
    38281 gaaaccaacg tttatgttca aataataatt ctaataattc taattgccta tgactttttt
    38341 tagataataa atctctcatg aatatctttc tctctttata aattatcgga ttaaacctct
    38401 tgcaattata ccacaaagaa taggtatagc atgatataac gacttttcct aaaatctttt
    38461 atttcgtata ataacactac ggagacaata tataaacaat tttcttattt tacc
//
LOCUS       DAVKZI010000018        36466 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKZI010000018 DAVKZI010000000
VERSION     DAVKZI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.018"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            97..597
                     /locus_tag="VXB18_001062"
     CDS             97..597
                     /locus_tag="VXB18_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382279.1"
                     /translation="MKNERRERWTQLSSQRMSRVLWTIELIANLSSHNYEYKDEWLGY
                     LFDSIKQKGDEIKEVFQNPTDALSNKLISEFEFPKEMFRSQPSPKELKFKNVAERRIT
                     KLYKEMNYFSRLANTKNYTYDSIDVDFLFDCYSNKYYELVSWFPPFIKDRVCNDINVA
                     DFPSER"
     gene            625..903
                     /locus_tag="VXB18_001063"
     CDS             625..903
                     /locus_tag="VXB18_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382280.1"
                     /translation="MNYWNDIKNIITEWHSIDYRVTEREDFETVKLRAIRNFQDYLKL
                     LDENTEEGYQEVIRLFTFSKFYGEELCNDEKLNKLSRDIRGRLKQFRS"
     gene            1165..2442
                     /locus_tag="VXB18_001064"
     CDS             1165..2442
                     /locus_tag="VXB18_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0382281.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2518..4002
                     /locus_tag="VXB18_001065"
     CDS             2518..4002
                     /locus_tag="VXB18_001065"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0382282.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            4063..5343
                     /locus_tag="VXB18_001066"
     CDS             4063..5343
                     /locus_tag="VXB18_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0382283.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGITGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            5347..5967
                     /locus_tag="VXB18_001067"
     CDS             5347..5967
                     /locus_tag="VXB18_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0382284.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6133..7275
                     /locus_tag="VXB18_001068"
     CDS             6133..7275
                     /locus_tag="VXB18_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0382285.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVFWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7681..8019
                     /locus_tag="VXB18_001069"
     CDS             7681..8019
                     /locus_tag="VXB18_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0382286.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8030..8388
                     /locus_tag="VXB18_001070"
                     /pseudo
     CDS             8030..8388
                     /locus_tag="VXB18_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8495..9113
                     /locus_tag="VXB18_001071"
                     /pseudo
     CDS             8495..9113
                     /locus_tag="VXB18_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9141..9998)
                     /locus_tag="VXB18_001072"
     CDS             complement(9141..9998)
                     /locus_tag="VXB18_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0382287.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10128..11270
                     /gene="tgt"
                     /locus_tag="VXB18_001073"
     CDS             10128..11270
                     /gene="tgt"
                     /locus_tag="VXB18_001073"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0382288.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11371..13188
                     /locus_tag="VXB18_001074"
     CDS             11371..13188
                     /locus_tag="VXB18_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0382289.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13341..14492
                     /gene="nagA"
                     /locus_tag="VXB18_001075"
     CDS             13341..14492
                     /gene="nagA"
                     /locus_tag="VXB18_001075"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0382290.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPYTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14655..15713
                     /locus_tag="VXB18_001076"
     CDS             14655..15713
                     /locus_tag="VXB18_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0382291.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15864..16229
                     /locus_tag="VXB18_001077"
     CDS             15864..16229
                     /locus_tag="VXB18_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0382292.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16305..17246
                     /gene="tadA"
                     /locus_tag="VXB18_001078"
     CDS             16305..17246
                     /gene="tadA"
                     /locus_tag="VXB18_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEV0382293.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLCLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     KDYQEHQPTSWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17194..18210
                     /locus_tag="VXB18_001079"
     CDS             17194..18210
                     /locus_tag="VXB18_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0382294.1"
                     /translation="MDISQVFRLKRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRTGLSQGKSFSEIMASLGFSSAIVTQLSLAEVHGNLHLSLRKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGFVSVGVLLALTFYKRSSKMRVFSILARIPFLGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQIMQEQGSQLFKEIGQDLAQSLQNGREFSQTIGTYPFFKKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18212..18274
                     /locus_tag="VXB18_001080"
                     /pseudo
     CDS             18212..18274
                     /locus_tag="VXB18_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGC"
     gene            complement(18292..19737)
                     /locus_tag="VXB18_001081"
     CDS             complement(18292..19737)
                     /locus_tag="VXB18_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0382295.1"
                     /translation="MKTMNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKLGRAKSGKSMMLA
                     KTSYGYDYHKETGTVTINPAQALTIKFIFESYLRGRSITKLRDDLNEKYPKHVPWSYR
                     AVRTILDNPVYCGFNQYKGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPF
                     QAKYILSGIAQCGYCGAPLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKC
                     DSGFYYKDKLEAYVLKEISKLQDDADYLDNIFLGDNAETIDRESYKKQIEELSKKLSR
                     LNDLYIDDRITLEELQSKSAEFISMRGTLETELENDPALRKNKRKADMRKLLNAEKVF
                     SMDYENQKVLVRRLINKVKVTAEDIVINWKI"
     gene            complement(20020..20454)
                     /locus_tag="VXB18_001082"
     CDS             complement(20020..20454)
                     /locus_tag="VXB18_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEV0382296.1"
                     /translation="MKFQQGEVYLINFPQKGGNEFYGKHYAIILTTPDKVDGTLLVAP
                     LTGKKSGKKYRGGITIENSKYQNTPSKPKAYAYVRKIQEIDKRKIVYKTKKKIDSDGQ
                     VMLDAAGKELYDKVYRPAYKLDTNDHKKLLDKIKEVLGLDLY"
     gene            complement(20639..21436)
                     /locus_tag="VXB18_001083"
     CDS             complement(20639..21436)
                     /locus_tag="VXB18_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEV0382297.1"
                     /translation="MKLGELLKSYRTEHKLSMDAFCELSDLTKGYISMLEKNEHPKSK
                     KPIVPSYDTIEKIAKGMQISTEDLIDMLDDDQEIQINATPALLSKSPIQTIYDELEPP
                     RQGKVLNYAKRQLDEQENEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTD
                     REIIEVDEQPPHHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAVIAYGDRSY
                     FKKIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVSVYRGE"
     gene            21591..21866
                     /locus_tag="VXB18_001084"
     CDS             21591..21866
                     /locus_tag="VXB18_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382298.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLETFSTNCRQF
                     TFGWTELADEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKMNVA"
     gene            21941..22108
                     /locus_tag="VXB18_001085"
     CDS             21941..22108
                     /locus_tag="VXB18_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382299.1"
                     /translation="MNESFLTILGISMIASFITNLIAYLAGKHHLKKKIKNHKMWFDS
                     EIERIKKKYHL"
     gene            complement(22099..22548)
                     /locus_tag="VXB18_001086"
     CDS             complement(22099..22548)
                     /locus_tag="VXB18_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382300.1"
                     /translation="MNNFSFIETLAIAAIPAFVSGMWSYIAAKGNSKHEIDKINIAHS
                     QELENVENQFKQDMEKMQKQHSQELYSLQQTHELRLLELEKVSQLDTQTDQGLKINDL
                     IFKAISGEISADVAIKNISTLSHFANKQQPSDLQKQFMKKLSKKNHK"
     gene            22791..23084
                     /locus_tag="VXB18_001087"
     CDS             22791..23084
                     /locus_tag="VXB18_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382301.1"
                     /translation="MEKLAEVTQEETEKILTYDEIVLLKPITHLHKSIFRQTEYLSEQ
                     LTERLHHLEDYNSPIDEETIRLAEVTIEFYNLLIKSPSISTVVKEIVSEGHKS"
     gene            complement(23019..23825)
                     /locus_tag="VXB18_001088"
     CDS             complement(23019..23825)
                     /locus_tag="VXB18_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HEV0382302.1"
                     /translation="MLSIDTQFVDTISKILSDYVSHSEITRMGEVLGYPQNDQNSGLN
                     KHHRVHNIMSDILNKTQDKSNIKLVIEYICNPLRYIDTVSDFENLRLKLNVVLSLKGL
                     TISDDGHVVITTASQTLVEAKKRFESLEHMLRTLNVHPNVLKFCTQELLQENYFHAVF
                     EASKGIFHRIRLLTGSSLDSASLIDQCFKTKEPIMIINGNKLQTLDEQSEYKGLKNLL
                     LTIAHLYRNSKAHKLKYYNPDSVHDALTALTLMSLAHNLLDNCTNTRRLD"
     gene            23872..24033
                     /locus_tag="VXB18_001089"
     CDS             23872..24033
                     /locus_tag="VXB18_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382303.1"
                     /translation="MRPIGYRLNVEVSGIEELKEACKEVSKKAEELQEAIDRLSIIEF
                     ELKAKPVND"
     gene            24086..24274
                     /locus_tag="VXB18_001090"
     CDS             24086..24274
                     /locus_tag="VXB18_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382304.1"
                     /translation="MQGERLRKWREKEKMSQEELAEKSNVSRTTIHLIESGQSSTVKI
                     RTLQKLAVVFNKQVKDFF"
     gene            24438..24704
                     /locus_tag="VXB18_001091"
     CDS             24438..24704
                     /locus_tag="VXB18_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0382305.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVSRDTVDSYFKILEKNGYLRI
                     VKKGMGRGKGVRVFRFFSDVKISDFQFEIMKQRLNESISKLSTG"
     gene            24897..25100
                     /locus_tag="VXB18_001092"
     CDS             24897..25100
                     /locus_tag="VXB18_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382306.1"
                     /translation="MRPRRYPYSGKKESTFVKADPELVEKLLRNTSFLERLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            25124..25849
                     /locus_tag="VXB18_001093"
     CDS             25124..25849
                     /locus_tag="VXB18_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEV0382307.1"
                     /translation="MNELINVTLNDNHEPVVSGRQLHEALGVKTKYADWFNRMIEYGF
                     TENQDFLLLKNEQQTGRGGHNKVDHIIKLDMAKEIAMIQRTERGKQVRQYFIQVEKDF
                     NSPEKIMARALLMADQKVHKLEAQIEADRPKVLFADAVSASHTSILVGELAKLISQNG
                     YKIGANRLFSWMRENGYLIKRKGSDWNVPTQRSMDLKLFEIMETNVQHADGHITVNKT
                     PKVTGKGQQYFINKFLNQEYLTG"
     gene            25921..26082
                     /locus_tag="VXB18_001094"
     CDS             25921..26082
                     /locus_tag="VXB18_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382308.1"
                     /translation="MKTVKKEWEPRIVNIMADGSQVDDLTGYVIPAGHSYYDIILGMN
                     KQSNEEGVA"
     gene            26082..26303
                     /locus_tag="VXB18_001095"
     CDS             26082..26303
                     /locus_tag="VXB18_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382309.1"
                     /translation="MKLLTKLKLRLEGVIKSVNLDWREVAIEVSNDLLEERKRRFMRE
                     QENHDLKQELAAYKYKENFDIKARLQGEM"
     gene            26304..26558
                     /locus_tag="VXB18_001096"
     CDS             26304..26558
                     /locus_tag="VXB18_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382310.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGTKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            26571..26825
                     /locus_tag="VXB18_001097"
     CDS             26571..26825
                     /locus_tag="VXB18_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382311.1"
                     /translation="MFKALKTIKKIKQLQKEMHDVSLAFLALQDVGLMLETERSKAKA
                     QTMHDVSHMLKDVLGGKSVDEAMKRLNSEVKIEDVEQEDD"
     gene            26818..26979
                     /locus_tag="VXB18_001098"
     CDS             26818..26979
                     /locus_tag="VXB18_001098"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382312.1"
                     /translation="MTRIELENRVWLLANHEEKKRIAGSWANVKDQICEASSGTRKGV
                     CSCLITTET"
     gene            27082..27312
                     /locus_tag="VXB18_001099"
     CDS             27082..27312
                     /locus_tag="VXB18_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382313.1"
                     /translation="MTQMTNKGKSFIRAEISEKQKEYIRLLAELRGVTTQELLGQVVE
                     RFIDRNLQLIQDYKNELDDLNSKSRRRIDMNT"
     gene            27324..28076
                     /gene="bet"
                     /locus_tag="VXB18_001100"
     CDS             27324..28076
                     /gene="bet"
                     /locus_tag="VXB18_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEV0382314.1"
                     /translation="MTNNQLATQTKRNITTDPSLLTGADIKKYFDPQNLLTEKQVGQA
                     LALCKGRNLNPFANEVYIVAYTNRNGGKEFSLIVSKEAFLKRAAQCKDYEGFEAGVVV
                     VDSEGVMHERKGAIMLPEDTLIGGWARVHRKNFKVPVEIFVSREEYDKKQSTWNTMPA
                     TMIRKVALVNALREAFPEDLGNMYTEDDGGETFDRIKDVTPQESREDVVARKMAEIEQ
                     FNKEQEANHADPEPAQTEETIQGELLDGELEY"
     gene            28086..29150
                     /locus_tag="VXB18_001101"
     CDS             28086..29150
                     /locus_tag="VXB18_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0382315.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKAGDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFEQ
                     IKADYEFEKQKEEIRQAQERAERESQELLAAQQTKQQERAPKSTGTPNFDPETGKILD
                     GGQILQNEPNALRGAENDLKRYAQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQV
                     RGYQRIEPLTQAELNEQCGW"
     gene            29153..29314
                     /locus_tag="VXB18_001102"
     CDS             29153..29314
                     /locus_tag="VXB18_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382316.1"
                     /translation="MTEIEKISEELAEYGVPDELIGKIEDLLATLYGEKKEIGDRKIL
                     DISPESMGR"
     gene            29317..29640
                     /locus_tag="VXB18_001103"
     CDS             29317..29640
                     /locus_tag="VXB18_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382317.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFNVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEIFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            29633..29968
                     /locus_tag="VXB18_001104"
     CDS             29633..29968
                     /locus_tag="VXB18_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEV0382318.1"
                     /translation="MIKTVFFSCDYPHHEVIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            30063..30479
                     /gene="ssb"
                     /locus_tag="VXB18_001105"
     CDS             30063..30479
                     /gene="ssb"
                     /locus_tag="VXB18_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0382319.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGIIGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            30489..30995
                     /locus_tag="VXB18_001106"
     CDS             30489..30995
                     /locus_tag="VXB18_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0382320.1"
                     /translation="MSKIKILDACCGSRMFWFDKNESHTIFMDIRQETFEIHDKKVNV
                     DPDIIGDFRDMPFEDNTFNLVVFDPPHLKWAGPNSIMKAQYGQLDKVTWSEDLAKGFE
                     ECLRVLKVGGTLVFKWSDRQINVKKLLEVIPFKPLFGQQRGTTHWLTFVKFEEDKNGV
                     DGLGGLET"
     gene            30961..31170
                     /locus_tag="VXB18_001107"
     CDS             30961..31170
                     /locus_tag="VXB18_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382321.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            31184..31513
                     /locus_tag="VXB18_001108"
     CDS             31184..31513
                     /locus_tag="VXB18_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382322.1"
                     /translation="MASKINATERIAIIIEKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            31510..31938
                     /locus_tag="VXB18_001109"
     CDS             31510..31938
                     /locus_tag="VXB18_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEV0382323.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEVEVMEWNA"
     gene            31982..32404
                     /locus_tag="VXB18_001110"
     CDS             31982..32404
                     /locus_tag="VXB18_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382324.1"
                     /translation="MTKTIELPDYYEPDWGNARYGTLEELKELLLYKRIVEWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQNVSLDAVITNVEIGEQEEIPDHWGAGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVGSLVIGDIHFPVVHA"
     gene            32449..32778
                     /locus_tag="VXB18_001111"
     CDS             32449..32778
                     /locus_tag="VXB18_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382325.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            32768..33439
                     /locus_tag="VXB18_001112"
     CDS             32768..33439
                     /locus_tag="VXB18_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0382326.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELARQIFLQDLEQLDESEIGYA
                     DEAPRYVKNILARLRELPLHDREVWLKAIMSEFEQDFSRAKWREGYEQGKIEGMVERE
                     KVKVPRFVAEWIEEARKACKDVVELFEFDFTNDEVRKWFMQERPFDLVARAWLDGYEV
                     EEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEEAGLGWVFDCEGVE
                     IEEVE"
     gene            33552..34001
                     /locus_tag="VXB18_001113"
     CDS             33552..34001
                     /locus_tag="VXB18_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382327.1"
                     /translation="MPNFAEGTIKLRGHAENIKSALKYMFEAAGDVTIEEDTDGELII
                     FTSSNSYFYINGTKRAFIDGESFEIHLDDDFLIIELNNFTQAWRAIPDNYIEISEKFN
                     VDIKIFTFEQGLEFTQEIEISKGKILKDIVLKYGDYRWEVAFSNLGG"
     gene            34020..34430
                     /locus_tag="VXB18_001114"
     CDS             34020..34430
                     /locus_tag="VXB18_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382328.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIISEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFVGDIIKCTRGCLHEVYIEKEYGGTYFGGMP
                     AVYLKDLREGYAWTEHEEIIGNIYENPELLEVNE"
     gene            34505..34747
                     /locus_tag="VXB18_001115"
     CDS             34505..34747
                     /locus_tag="VXB18_001115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0382329.1"
                     /translation="MVDKYIDEPHTTFIPVINGKSSVLVPTRTKRKYILVISGYAGNK
                     QVEERFEVTANEYKHYEIGNTFIQDAVLENKEEDKE"
     gene            34744..35109
                     /locus_tag="VXB18_001116"
     CDS             34744..35109
                     /locus_tag="VXB18_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382330.1"
                     /translation="MKPKKYPYSGKMQKIPSPIFSARPIFNEVPIVEEVKVEFGVEAS
                     MGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRFLT
                     FRESDWKFFIRDLVNEFVR"
     gene            35179..35601
                     /locus_tag="VXB18_001117"
     CDS             35179..35601
                     /locus_tag="VXB18_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0382331.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWIDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRLINKLKNPKSRSILRVTYITK
                     MYVDDICDKMEISRTTFYTWRNMAISELNEVLERMELN"
     gene            35687..35769
                     /locus_tag="VXB18_001118"
     tRNA            35687..35769
                     /locus_tag="VXB18_001118"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35718..35720,aa:Tyr,seq:gta)
     gene            36036..>36466
                     /locus_tag="VXB18_001119"
     CDS             36036..>36466
                     /locus_tag="VXB18_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0382332.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEA"
BASE COUNT        11449 a         6282 c         8087 g        10648 t
ORIGIN      
        1 aaccttatta attagaataa aaatatttag ggttttattt ttacggattt tgatatataa
       61 tatcatttag tattatttta taattaggag aagacaatga aaaatgaacg cagagagcga
      121 tggacacagc ttagctcaca aagaatgtca cgagtattat ggacaataga attaattgca
      181 aatctatcta gtcacaacta tgaatataaa gatgaatggc ttggatattt atttgattca
      241 atcaagcaga aaggagatga gataaaagaa gtatttcaaa atcctaccga tgcattatct
      301 aataaattga tttcagaatt tgaatttcca aaagaaatgt ttcgttctca acctagccca
      361 aaagaattaa aatttaaaaa tgttgcagaa agaagaatta ctaagctata taaagaaatg
      421 aactatttta gccgattggc taataccaaa aattatacat acgactctat tgatgttgac
      481 tttctatttg attgttactc aaataaatac tacgaattgg tgagctggtt tcctccattt
      541 ataaaagaca gagtttgcaa tgatattaac gtagctgatt ttccaagtga aagatagtta
      601 aattctatga tttggagaag gaaaatgaac tattggaatg atattaaaaa tataataaca
      661 gaatggcact ctattgatta cagagttacg gaacgagaag attttgaaac agtaaaacta
      721 agagcaatta gaaattttca agattatcta aaattacttg atgagaatac tgaagaaggc
      781 taccaagaag ttataaggtt atttacattc agcaaattct atggtgaaga actgtgtaat
      841 gatgaaaaac tgaacaaatt gagtagagat ataagaggga gattaaaaca attccgttcc
      901 taaaatgtta ctaaaaataa aaaaactatc gtttttgtga tagaggtaac tttttgaaaa
      961 ggctatttga ctggctttat atacttatga aacgttaaga gtccaactca aaatccagtg
     1021 tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt aggaacgttg
     1081 ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc aaattttgtt
     1141 tagattgaga aagtgtaggg tagtatgtct tgttctatcg atttattaaa acatcggtat
     1201 ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga gtatcctgtt
     1261 gcaagtttag aaggggatgc tacagatgtt gaagttataa aggatctatt tcattattta
     1321 gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct gatccagtta
     1381 gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac gattgagttt
     1441 gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa ttatatgaat
     1501 gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg tatccatccc
     1561 aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat gttgatggat
     1621 tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc tgaatatggt
     1681 acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta cttacgggtg
     1741 attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa ctctgaattt
     1801 tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga atctatgcat
     1861 ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga agctgatttt
     1921 tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca gacctattat
     1981 ttttatccta ttcaggctgg ggactatttg gctacgcctg aaatccaagc attttctctg
     2041 aatggggatg aggttattat ttccccccaa gagaaggatt ttgaaactca tcgtagttac
     2101 cagtaccaag acttaacgac tcgaggaaca gttgagtttc gtagtgtgtg tacacagcca
     2161 cttgatagaa cttttgcttc tgcagctttt cacttgggat tattggttaa tttagacaag
     2221 ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga ttacaagtct
     2281 ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac gattattgaa
     2341 ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa taaggaagaa
     2401 atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt ataaagggag
     2461 aattttctga aaaatcatga tataatggac gagactatag ataaaggata gagagtaatg
     2521 acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag ccaagcaatt
     2581 ttgcaaggtt tagcgacgga cggcggtttg tttacaccgg ttacttatcc aaaggtagat
     2641 ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct agttttgtca
     2701 gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa tgcctacgat
     2761 agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca atacaatttg
     2821 gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat tttgccatac
     2881 tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat cttgacagcg
     2941 acatctggtg acacggggaa agctgctatg gcggggtttg cggatgtgcc tggtactgag
     3001 attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca aatgaccact
     3061 cagactggcg acaatactca tgttattgct attgatggta actttgacga tgcgcaaaca
     3121 aatgtgaagc acatgtttaa cgatgtggct cttcgtgaaa aattgactac caacaagttg
     3181 caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat tgtttattat
     3241 gtttatgcct acgctcaatt ggttaagact ggtgaaattg tagctggtga aaagattaac
     3301 ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc caaacaaatc
     3361 ggcctaccag ttggcaagct aatctgtgct tcaaatgaca acaatgtttt gacagacttc
     3421 tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag cccatctatg
     3481 gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg aaataatgct
     3541 gaaaagacag ctgaacttat gaatgccttg aacacgcaag gacaatataa gttgacagac
     3601 tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga agaaacagcg
     3661 gcagaaatca agcgtgttta tgagtcagat tcttatattg aggatccaca tacggcggtt
     3721 gcctcagcag tttatagaaa ataccaagcg gttactgatg atgcgactaa gacagtgatt
     3781 gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt aactggaaaa
     3841 gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg cgttgcagtg
     3901 ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac agtggcagct
     3961 gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg gagcaaactc
     4021 ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa gaaaaataaa
     4081 gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat gctaatggga
     4141 atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg ggtttcagta
     4201 gctggtaata ttatcaccat ttatcaggcg atcttcatcg ctctgggagc tgctatttcc
     4261 agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta tcatgtgact
     4321 gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc catcttcgct
     4381 gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag tggtggactg
     4441 tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag tttgggagcc
     4501 ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt atccaatgcc
     4561 ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat aactggtgtt
     4621 gcttggggga caattctgtc tcgtttggtt ggtcttgtga ttttgtggtc acaattaaaa
     4681 ctgccttatg ggaagctaac ttttggttta gataaggaac tgttgacctt ggctttacca
     4741 gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc cttggtcgtt
     4801 tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac ccagtttaac
     4861 tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg agcagttgga
     4921 gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct ttctctgttc
     4981 ctcatgttac ccctgtcctt tagtatatat gtcttgggtg taccattaac tcatctctat
     5041 acgactgatt ctctagcggt tgaggctagt gttctagtga cactgttttc actacttgga
     5101 acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt aggaaatgca
     5161 cgcctccctt tttatgcgac aagtataggc atgtggtgta tccgcattgg aacaggatat
     5221 ctgatgggga ttgtgcttgg ttggggctta cctggtattt gggcagggtc tctcttggat
     5281 aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgat cttgaaagga
     5341 taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt ggactcttac
     5401 gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc ttatgataag
     5461 gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt gcgggtggca
     5521 gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag tctggctgag
     5581 aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg ggcagacgaa
     5641 tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac cattctcaag
     5701 gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg ctttgtgcgg
     5761 aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa ttctgataat
     5821 acttattata taggggatcg gactctggat gtggaatttg cccagaatag tgggattcaa
     5881 agtatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc gttagcagat
     5941 atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt gacagagacc
     6001 taacaaacta tttcaagtaa tcgagtttgt tacaaggaat agacagttct gttaaatagg
     6061 cccgagaggg ctttttttct acattttttg tgttatcata gacaggtact catttgaaag
     6121 gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtggcctt gtcatttgcc
     6181 ccagtattgg caactcaagc agaagaagtt ttttggactg cacgtagtgt tgagcaaatc
     6241 caaaacgatt tgactaaaac agacaacaaa acaagttata cagtacagta tggtgatact
     6301 ttgagcacca ttgcagaagc cttgggtgta gatgtcacag tgcttgcgaa tctgaacaaa
     6361 atcactaata tggacttgat tttcccagaa actgttttga caacgactgt caatgaagca
     6421 gaagaagtaa cggaagttga aatccaaaca cctcaagcag attctagtga agaagtgaca
     6481 actgcgacag cagatttgac aaccaatcaa gtgaccgttg atgatcaaac tgttcaagtt
     6541 gcagatcttt ctcaaccaat tgcagaagct ccaaaagaag tagcatcaaa ttcagaagtt
     6601 gcagagacag tgactgctgc agaagaagtg gcactatcta cagactctac tacgccagag
     6661 ggacaaccag ccgaaacaac tagtccagtt gaagaagcaa ctcctcagga aacgactcca
     6721 gctgagaagc aggaaacaca agcaagccct caagctgcat cagcagtgga agcaactaca
     6781 acaagttcag aagcaaaaga agtagcatca tcaaatggag ctacagcagc agtttctact
     6841 tatcaaccag aagagacgaa aataatttca acaacttacg aggctccagc tgcgcccgat
     6901 tatgctggac ttgcagtagc aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc
     6961 tttaaagaag aaattgctaa cttgtttggc attacatcct ttagtggtta tcgtccagga
     7021 gacagtggag atcacggaaa aggtttggct atcgatttta tggtaccaga acgttcagaa
     7081 ttaggggata agattgcgga atatgctatt caaaacatgg ccagccgtgg cattagttac
     7141 atcatctgga aacaacgttt ctatgctcca ttcgatagca aatatgggcc agctaacact
     7201 tggaatccaa tgccagaccg tggtagtgtg acagaaaatc actatgacca cgttcacgtt
     7261 tcaatgaatg gataaacccg acttggtaac atcattttga cgaatgagat ctagctttcg
     7321 tgataggaag cgattctcgt tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa
     7381 ccacgtcagt tttatctgaa acctcaaagc tgtgctttga gcaacctgcg actagctttc
     7441 tagtttactc tttgattttc attgagtatc aatttgaatg gaaaatggaa agttattatc
     7501 ttgtaataat ccaagcaaca ttcttgcaat ctattttact ttatatcaca attgattggt
     7561 caactattga taagtcaatg gataggagga agaaatgata gagattcaag atttactgta
     7621 tcaactccgc ttgtctgagc aagcgagtac gcaattgttt gaaaaaggct tgggattagt
     7681 ttgacacggt atcagatttt actgtttttg ctggagcatt ctccttgtaa ccaaatggcg
     7741 gttcaggagc gtttgaaaat tgatcaggct gctttgacac ggcatttcaa gattttggaa
     7801 acggaaggtt tggtggagcg tcatcgtaat cctgaaaatc agcgggaagt gttggtagag
     7861 gctgcgaagt atgccaagga gcagttagtg gtgaatcccc ctctgcaaca tatcaaggtt
     7921 aaggaagaga tggaaagtat cttaacagag tttgagagaa cagaactcag ccgtttatta
     7981 aataaattgg ttttgggtat tgaaaatata gaaatttaag gagaaataga tgtcaattat
     8041 tttaacaacg atcgttgctt tggagcattt ttacattttt tatttggaaa gtattgccac
     8101 gcaatcagat gcgactagtc gtgtatttaa tatggaaaag gaagaattgg ctcatccgtc
     8161 agtaagttca ttgttcaaaa atcaaggaat ttataaggct ctgctaggag tctttctctt
     8221 gtatgtcatt tatttctcac agaatttaga aattgtgact atttttgtct tatttgtgat
     8281 tggtgctgcg acttacggct ctttaacagc ggataaaaaa ttattttgaa gcaaggtgga
     8341 tcagctattt tggccttgat tagtatttta ctctttaaat acacttgaag gttgattcta
     8401 atctcgctaa tcctttttaa tccagaataa gggaaatatg ttatacttgt ttttaagaaa
     8461 aaagtctcat tgaattggtt ttgaggagtt agaaatgaaa gtattagtga caggttttga
     8521 gcccttttga ggccattaaa ggtttaccag ctgaaatcca tggtgctgag gtccgttagc
     8581 tagaggtgcc gacagttttt cacaaatctg ctcaagtatt ggaagaagag atgaatcgtt
     8641 atcaacctga ctttgtcctt tgtattgggc aagctggtgg aagaactagt ttgacacctg
     8701 aacgagtggc cattaatcaa gacgatgcac gcatttctga taacgaagat aatcaaccga
     8761 ttgaccgtcc cattcgccca gatggtgctt cggcctactt tagtagtttg ccgattaaag
     8821 cgatggttca agatataaaa aaagagggct taccggcctc tgtttccaat acggcaggga
     8881 cttttgtctg cagccatttg atgtatcagg ctctctattt ggtagaaaag aaatttccat
     8941 atgttaaggc aggttttatg catattcctt atatgatgga acaggtggtg aacagaccga
     9001 ctactccaac tatgagttta gtggatattc ggcgagggat agaagcagca atcggcgcta
     9061 tgatagaaca tggagatcag gaactcaagt tggtaggcgg agaaactcat tgatagaaaa
     9121 aagcttgagg ggaaaaacct tcaagctttt ggacgttttc gagccaatac tgctcggtaa
     9181 aacataattt tagtgcattg gatataaggt aggagtgaaa aactagcaat gccaaaggta
     9241 atccaattga ggaagtacca aggaagaagc tgtaaatcta ggacaaagtg ctggaacttg
     9301 tagcccttca taaaggaacg gctagttttt aggattcgtc ttggtgggac ctgtcctagg
     9361 tctagactat aacagagaag aaattccacc tgtgaatagg cataatactg tggaatatag
     9421 aggatatttc ctacaatgat caagatgaga cttgcaagaa agtagagtcc aaagaccatg
     9481 aggaaacgct cggtttcaac tgatgagaga tctagatttg gaaactcagg atgtagggtg
     9541 acgaattttt tggctaaaaa gctactataa aagaggaggt aaatcccaag taaattaggg
     9601 atactccata aaaagagata gaaacgtttg agaagtaggg tcaaaaaggt ttgagaaaag
     9661 cgctcctcat caaagagagc taggctgttt tttacagatg gctccgtttt agaatctttc
     9721 atgagtgtca gtgttgcata gacggaactg gtcaaaagaa tagtcccgat aaaggagact
     9781 agtagaggaa agaggtaggc ttgaagtatt tggccaagta tgctgaaaaa tggctgttct
     9841 aaaacagtcc cgtggatccg agataaggga ttaagaaaac tagataagat gaccagcata
     9901 ctgggaagga tatagaggag aaagagacgg ggggtgtcag cctgaaaatg ttttgactcc
     9961 tgacgaattg tttttaaatc aatttttgga tagttcattc tcttattata ccatagttct
    10021 tatacatagt tcgtgacagt tcctactttt tttgataaaa tcatacagtg tgtccttggg
    10081 cacactgtat gaactgggac tgtctttccc agcttcggag gtaaaaaatg tcagattcac
    10141 caatcaaata tcgtttgatt aagaaagaaa aacacacagg agctcgtctg ggagaaatca
    10201 tcactcccca cggtaccttt ccgacaccta tgtttatgcc agttgggaca caagccactg
    10261 tcaaaactca gtcacctgaa gaattgaagg agatgggttc gggaattatc ctatcaaaca
    10321 cctatcatct ctggcttcgc cctggagatg aactcattgc acgcgctggt ggtctccaca
    10381 agttcatgaa ttgggaccag cctatcttga cagatagtgg tggttttcag gtttattctt
    10441 tagcagatag ccgtaatatc acagaagaag gagtaacctt taaaaatcat ctaaatggtt
    10501 ctaagatgtt cctatcccca gaaaaagcca tctctattca gaataatctg ggttcagata
    10561 tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc ttatgactac gttaagaaat
    10621 cgatcgagcg taccagccgt tgggctgagc gtggtttgaa ggctcaccgt cgtccacatg
    10681 accaaggttt gtttggaatt gtgcaaggtg caggatttga agaccttcgc cgccaatcag
    10741 ctcatgatct tgtcagcatg gatttctcag gctactctat cggtggtttg gcagtgggag
    10801 aaacccatga agagatgaat gcggtcttgg actttacaac tcaactgcta cctgaaaata
    10861 aacctcgtta tctgatgggt gtgggagcgc cagatagctt gatcgatggg gtcattcgtg
    10921 gggtggatat gtttgactgt gtcttaccga ctcgaattgc tcgtaacggg acttgtatga
    10981 ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc tgaggacttt acgccactgg
    11041 atcctgagtg tgattgctac acatgtaata actatacacg cgcttacctt cgtcacctgc
    11101 tcaaggctga tgaaaccttt ggtatccgct tgactagcta ccacaatctt tacttcttgc
    11161 ttaacttgat gaagcaagtg cgacaagcca tcatggatga caatctcttg gaattccgtg
    11221 agtattttgt ggaaaaatat ggctataata agtcaggacg taatttttaa aatggaattg
    11281 atataagcta aaaatcctaa gttttctctt aggatttttc ttcttttttt gatagaataa
    11341 agtgtacaat gaaaggaaga ataaactcgt atgcgcatta aatggttttc cttgattagg
    11401 attataggtt tacttttggt actcttgtat cacttctttc agacgatctt tcctggagga
    11461 tttttcgggg tagatgtctt tttcacattt tcaggtttcc tgattacagc tctactcatt
    11521 gaagaatttt ctaagaacaa tgagattgat ttgataggat tttttagaag acgcttttat
    11581 cggattgtgc cacctgtggt tttgatggtc ttggtgacca tgccttttac tttcttggtt
    11641 cgccaagact atgttgctgg aattggtggc cagattgcga gcgtcttagg ctttatgacc
    11701 aacttctatg aactcctaac aggtgggagt tatgaatctc agttcattcc tcatttgttt
    11761 gttcataatt ggagtttggc agttgaggtt cactactata ttctttgggg attggcagtt
    11821 tggttcttat ccaaacaagc taaatcaaat ggtcagttga aggggatggt ctttctctta
    11881 tctgctgttg ccttcttgat cagtttcttc tccatgttta ttggtagttt tctagtgacc
    11941 tcttattcct ctgtttattt ctccagttta actcatgtct atccattctt tttaggaagt
    12001 atgttagcaa ctattgtagg cgttcgtcag acgacttccc tcgtcaagca gttggataaa
    12061 atctgggatt tacgaaagac tttggtagtt tttggaggag gctttggttt cctagttctt
    12121 ttgactttct ttgtcaaatt cacttatctt tttgcctatc ttatcggctt cttacttgcc
    12181 agtcttgcag ctcttgccat gattctggcg gcgcgtgtct tacatgaaaa gacacatcat
    12241 atacaggagc cgaagattat cagcttttta gcggatacta gctatgcggt ttatcttttc
    12301 cattggcctt tctatatcat tttctcacag ttgacatcaa atcttcttgc tgtattactg
    12361 actctgattt gttcttatgg ctttgccagt ctgtcatttt atgtattgga accttggatt
    12421 gcaggcaaga acacacctat tttacaaact cttcgtcccc tgccttatat tcacgcaatt
    12481 cttgcagcag gtacaggaat cttgaccttc attgtctgca tggtgacctt gttggcacca
    12541 caagtgggag cgtttgagac agacttgact gtcaatggct tgaagcaagc tgcaacaaat
    12601 attggccaga ccaaggtgat ggcagaacgg gcagatgcaa acagtttggg aattgctgat
    12661 ggcactatgt taattggtga ctcagtggct ttaagggcaa atacagcact acagacagct
    12721 cttcctggag cacagattaa cgcgcaggtc agcgtaacaa ccaagaccgc aaatgaaatc
    12781 atgctaaata atagccagaa taaattttta cctaagacgg tggtcattgc gactggggta
    12841 aataatcctg agaattacaa ggatgactgg gacagtatcg tgaaaaatct tcctaaggga
    12901 caccatatga ttttggtgac tccttatgag ggagataaga caaaagagac ctatgccatc
    12961 gttgagaagg ctgctgccta tatgagagaa ttggcagaga agacacctta cattacgata
    13021 gcagattgga atcaagttgc gaaagagcat ccagaaattt gggcaggaac agaccaggtt
    13081 catttcggga gtgagagtag cactatcgaa gcaggagcaa aattgtatgc agatacgatt
    13141 gccacagctt tgcagacagc tcaagataag ccggttaaat caaaataact tgtattaaaa
    13201 aagagaagag ttggagaaat ccagctcttt taaaatatct ccaaaaaata ggtctatacc
    13261 atttacaaat aaaaaagaaa ggtttataat gtaattgaca taataaattg tagaatcaat
    13321 cttttaagga ggttaacatt atgcctaact atattaaagc ggatcagttt ttctacccac
    13381 acggagttcg tcgaggtggt tacttggaac ttgtggacgg caagtttggg aaacatgtag
    13441 agcagattcc tgaaggggct gaggtgattg actatacagg ttatagcatt gccccaggtc
    13501 ttgtggatac tcatattcat ggatatgcag gtgtagatgt gatggacaac aacattgaag
    13561 gtacattgca tactatgagt gaaggacttc ttagtaccgg tgttaccagt ttcttaccca
    13621 caactttaac agccacttat gagcaattgc ttgcagtcac tgaaaatctt ggaaaccatt
    13681 ataaagaagc aacaggtgct aagattcgtg ggatttatta tgaaggtcca tatttcacag
    13741 aaacttttaa gggggcacaa aatccaactt atatgagaga cccgggtgtt gaggagtttc
    13801 attcttggca aaaagcggca aatggcttgc ttaataaaat tgcccttgca ccagaacgtg
    13861 atggggtgga agactttgtt cgtacagtta cgggcgaagg tgtgacggtt gctcttggac
    13921 attcaaacgc gacttttgat gaagccaaaa aagcagtcga tgctggagcg agtgtttggg
    13981 tgcatgccta caatggaatg cgtgggttga ctcaccgtga attgggtatg gttggagcca
    14041 tgtaccaatt gccatatacc tatgcagagt tgatctgtga tggtcaccac gtagatccaa
    14101 aggcttgcga aattcttatc aaacaaaaag gaacagaaaa catcgctctt atcacagact
    14161 gtatgacagc tgggggattg gaagacggag attatatgtt gggagaattc ccagttgtcg
    14221 ttgcaaatgg aactgcacgc ctcaaatcga caggtaactt ggcaggttct atcctcaaac
    14281 tcaaagatgg tttgaagaat gtggtcgaat ggggaattgc gaatccgcat gaagcagtca
    14341 tgatggccag cttcaaccca gctaaatccg ttcacatcga tgacgtctgt ggccaaatcc
    14401 gtgaaggcta cgacgctgac ttcatcgtat tagataaaga tttggaattg gtagcaacct
    14461 acctagatgg tgtgaaacgt tatcaagcat aagagagaag gcagaagtta gagactagct
    14521 tctgcttttt tatacagggt actttactgg taaataaaaa gttaaaaaaa tcacaaaaaa
    14581 agcttgaaga aacaaagaaa aaggcttaca attgaactat aaatattaca aataaaaaaa
    14641 cggaggagtg ctttatgaaa gcctatactt atgttaaacc aggacttgct tcttttgttg
    14701 atgtagacaa accagttatt cgcaagccaa cagatgctat tgtgcgtatt gtaaaaacca
    14761 ctatttgtgg aacagacctc catattatca aaggggatgt tcctacttgc caaagtggta
    14821 ccattcttgg ccacgaaggg attgggattg ttgaagaagt tggggaagga gtttccaact
    14881 tcaaaaaagg tgacaaggtc ttgatttctt gcgtctgtgc ctgtggtaaa tgctactact
    14941 gtaaaaaagg aatttatgcc cactgtgaag acgaaggggg ctggattttc ggtcacttga
    15001 ttgatggtat gcaggctgaa tatctacgtg tccctcatgc agataatact ctttaccata
    15061 ctccagaaga cttgtcagat gaagctttgg ttatgctgtc agacattctg cctactggat
    15121 atgaaattgg tgtcttaaaa gggaaagtag aacctggttg cagcgtagcc attattggtt
    15181 caggtccagt tggattggct gctcttttaa cagcccaatt ctattcacca gctaaattga
    15241 ttatggtaga cctagacgat aaccgcttgg aaactgccct atcattcggt gcgactcata
    15301 aggttaattc ttcagaccct gaaaaagcca ttaaagaaat ttatgatttg acagatggtc
    15361 gtggtgtgga tgtcgctatc gaagctgttg gtattcctgc aacatttgat ttctgtcaaa
    15421 agattatcgg tgtagacgga acggttgcca actgtggtgt gcatggtaaa ccagttgaat
    15481 tcgatttaga taaactttgg attcgcaaca tcaatgtaac aactggtttg gtatctacaa
    15541 atacgactcc acaattgttg aaagcacttg aaagtcataa gattgaacca gaaaaattgg
    15601 taactcacta tttcaaactc agtgaaattg aaaaagccta tgaagtcttc agtaaggcag
    15661 cagaccacca tgccattaag gtcattatcg aaaacgatat ctcagaagcc taagtagtaa
    15721 aaatattttt gtacataagt aaatagaaat tcagtcatcc atcagatggc tggatttttt
    15781 atcaaaaaat taagaaatga gcatatttct ttccttgtct ggcggaattg gttataatat
    15841 acggtacaaa ggaatgaatg aatatgtatc gtgttataga aatgtacgga gattttgaac
    15901 cgtggtggtt cttagaaggt tgggaagaag atattgtagc aagtagaaaa tttgaccagt
    15961 attatgatgc tctcaaatac tacaaaactt gctggtttag attggaacaa gaatcccctc
    16021 tttataaaag tagaagcgac ttgatgacca ttttttggga cccggaagac caacgctggt
    16081 gtgatgaatg tgatgagtat ttacaacaat accattcttt ggctcttttg caggatgagc
    16141 aggttatccc agacgaaaaa ctacgctcag gctatgaaaa acaaaccagt caggaaagga
    16201 atcgttcttg ccgtatgaaa ttaaaataga gaaaagtaac ttttttggag ttgctttttt
    16261 tatttttcta acgctttgcg aatagtatag gtgaggaggt aagtatggtt caagaaattg
    16321 cacaagaaat cattcgttca gctcggaaaa aagggacgca ggatatttat tttgtcccta
    16381 agttagacgc ctatgagctt catatgaggg taggagacga gcgctgtaaa attggtagct
    16441 atgattttga aaagtttgca gccgttatca gtcactttaa gtttgtggcg ggtatgaatg
    16501 tgggagaaaa aagacgtagt caactgggtt cctgtgatta tgcctatgac cagaagatgg
    16561 cgtctctatg tttatctact gtaggcgatt atcggggaca tgagagtttg gttatccgtt
    16621 tgttgcacga tgaggagcag gacttgcatt tttggtttca ggatattgaa gaattaggca
    16681 agcagtacag gcaacgggga ctctatcttt ttgctggccc ggttgggagt ggtaagacga
    16741 ccttgatgca tgaattgtcc aagtcactct ttaaaggaca gcaagttatg tccatcgaag
    16801 atcctgtcga aatcaagcag gacgacatgc ttcagttgca gttgaacgaa gcaatcggcc
    16861 taacctatga aaatctaatc aaactttcct tgcgtcatcg accagacctc ctgattatcg
    16921 gagaaattcg agacagcgag acggcgcgtg cagtagttag agctagtctg acaggtgcga
    16981 cagtcttttc aaccattcat gccaagagta ttcgaggtgt ttatgagcgc ctgctggagt
    17041 tgggtgtgag tgaggaggaa ttggcagtcg ttctgcaagg agtctgctat cagagattaa
    17101 tcgggggagg aggaatcgtt gactttgcaa acaaagacta tcaagaacac cagccaacta
    17161 gctggaatga acagattgac cagcttctta aagatggaca tatcacaagt cttcaggctg
    17221 aaacggaaaa aattagctac agctaagcaa aaaaatatca tcaccttgtt taacaatctc
    17281 ttttccagcg gttttcatct ggtggagacc atctcctttt tagataggag tgctttgttg
    17341 gacaagcagt gtgtgaccca gatgcgcacg ggcttgtctc aggggaaatc attctcagaa
    17401 ataatggcta gtttgggctt ttcaagtgcc attgtcactc agttatccct agcggaagtc
    17461 catggaaatc tccacctgag tttgagaaag atagaagagt atctagacaa tctggccaag
    17521 gtcaagaaaa aactaattga agtagcgacc tatcccttga ttttgctggg ttttcttctc
    17581 ttaatcatgc tgggactacg gaactatcta ctaccacaac tggatagtag taatattgcc
    17641 actcagatta tcggtaatct gccacaaatc tttctaggaa tggtaggatt tgtttcagta
    17701 ggtgtccttt tagcactcac tttttataaa agaagttcta agatgcgcgt cttttctatc
    17761 ctagcacgca ttccttttct tggaatcttt gtgcagactt atctgacagc ttattatgcg
    17821 cgtgaatggg gtaatatgat ttcgcagggg atggaactga cgcagatttt tcagatcatg
    17881 caggaacaag gttcccagct ctttaaagaa atcggtcaag atttggctca gtccctacaa
    17941 aatggccgtg aattttctca gacgatagga acctatcctt tctttaaaaa ggagttgagt
    18001 ctcatcatcg agtatgggga agtcaagtcc aagctgggta gtgagttgga aatctatgct
    18061 gaaaaaactt gggaagcctt ttttacccga gtcaaccgca ccatgaatct ggtgcagcca
    18121 ctggtcttta tctttgtggc tctgattatt gttttacttt atgcggcaat gctcatgccc
    18181 atgtatcaaa atatggaggt gaatttttaa catgaaaaaa atgatgacat tattgaaaaa
    18241 agcgaaggtt aaagctttta cacttgtgga aatgtaggtt actaaaatta tttatatttt
    18301 ccaattgata acaatgtcct cagctgtcac cttaaccttg tttataagcc ttctaacaag
    18361 caccttttga ttttcgtagt ccattgaaaa gactttctca gcgtttagca gtttcctcat
    18421 atcagccttt cttttgttct tcctgagtgc tggatcgttt tctagttcag tttcaagagt
    18481 ccccctcatg cttataaatt cggctgactt gctctgtaat tcttcaaggg taatgcggtc
    18541 atctatgtat agatcgttaa gtctgctcag tttctttgat agctcctcta tttgtttctt
    18601 atagctctca cggtctatgg tctcagcatt gtctcctaaa aatatgttgt ccaggtaatc
    18661 agcgtcatct tgtagtttgc ttatttcttt tagcacatag gcctctagct tgtctttgta
    18721 gtaaaatcct gagtcacact ttttattgtc gttgtaggta gtaacgcctc tcagcgttcg
    18781 tgggtgcctt tggtggcatt catatttttt taacctgctc ccatctttcc tctttacgcc
    18841 taacataatt tttaaaggag cgccacaata tccacattgg gcgataccgg ataaaatgta
    18901 cttagcttgg aatggtctag gattgacatt ctctgctgct gttctttgtc ttatttttag
    18961 ctcagattga gtcttatcgt attcctcttt tgaaataatc ggctcatgat tacctggata
    19021 aatttctccc ttatactgat tgaaaccaca atagacaggg ttatcgagta tggttctgac
    19081 cgcccgatag ctccaaggca catgctttgg gtatttctca tttagatcat ctctcaactt
    19141 agtaatagat ctccctctca ggtaactttc aaagataaac ttaatggtca gagcctgagc
    19201 tggattgatg gtcactgtgc ctgtctcttt gtggtaatcg taaccatagg atgtcttagc
    19261 caacatcatg gatttaccag atttggcacg tcctagcttg ccaagttgca tgcgttcctt
    19321 gatttgctcc ctttctagct gagcaaagac gctcaagagt ccaatcatag ccttaccaaa
    19381 aggagtagag gtgtcaaagt tctcctgcaa gctcagaaat tcaatcccat tcttgatgaa
    19441 tacatcctca atcaagtgaa gcgtgtcttt ttgactacgg ctaagacggt ccagcttata
    19501 gactagaact gtgtcaaatt ttcttttttt agcgtctttg ataagacttt ctagcgctgg
    19561 tctgtcagta ttggatcctg agaaacctcc atcagtatat actttgtata cattccagtc
    19621 tttaatgtcg cagtagctag agagcttgtc tttttgctca tctatagagt atccctcctc
    19681 aacctggttt gtcgtcgaaa ccctgacata tatagccact ttattcattg ttttcattga
    19741 atttgtaccc cttttttgat aaaataggta caagaaaaac agctttttaa tgcttttttc
    19801 ttgctcctag cctcacgctc tcggtcgcca aacttctgag cgtggggctt ttttgagttg
    19861 tttccaaaat ggaaacagtt gctagataaa aagaaaagca gccgtatcaa atacggctac
    19921 catcacgtta tggatctaaa atccaaacct aaactttatg gagctaaact cctgatagct
    19981 gtattgtaat ataattattt aaaaacgtca attttttatt taatataaat ctagtccaag
    20041 aacttctttt atcttgtcta gtagtttttt atggtcgttt gtatctagct tgtaagctgg
    20101 tctataaact ttatcatata actcttttcc tgctgcatct agcattactt gtccatcgct
    20161 atcaatcttt ttctttgttt tatagacgat tttccgtttg tctatttctt ggatttttcg
    20221 gacataagca taggctttgg gcttggacgg agtgttttga tatttactat tttcaatcgt
    20281 gataccacca cgatatttct ttcctgattt tttaccagtt aaaggtgcta ctaggagcgt
    20341 tccatcaact ttgtcaggag ttgttaagat gatagcgtag tgttttccgt aaaattcatt
    20401 cccacctttt tgtgggaagt tgattagata aacttcgcct tgttgaaatt tcatataatg
    20461 ctccggataa taaaataagg tgtacctctt agaagtacac cagaccgttt tgtccttgac
    20521 gaacaaggct ttataaataa atatcgtatc cttgacgaac aaggcttttg acattattag
    20581 tgtacttctt tttttagttt ttgtcaagta gttgtttcca ttttggaaac agttggtttt
    20641 attcccctct atacacactg acaactgcat agatcttgat gtgtgtgtct tcggctggtg
    20701 ggaagtctag gatgatatct tcgtacttgt cattgagcga cactaggcgt aagcgtccgt
    20761 tttcggtata tatcttctta aagtaagaac ggtctccgta tgcgataact gctaggtctc
    20821 cgttgtaggt ggtcagtccc ttgtctacta aatagagaat atctccgtct tggtagtcag
    20881 gttgcatgga gtctccgctg accttagtcg caatatcgtg atgtggtggt tgctcgtcga
    20941 cctctataat ctctctgtct gtatcgtcgt acccaaatcc atagttaaat ccagaagctg
    21001 ctgccgtctc agatacaacc tcaacttggt acaagctgat aacttccgat acttcgttta
    21061 tcttcgtttc ttcttcgttt tcctgctcgt ccagttgcct ctttgcataa ttcaggactt
    21121 tgccctgtct aggtggttct agttcgtcgt agatggtttg gattggggat tttgaaagaa
    21181 gagctggagt agcgttgatt tgaatttctt gatcatcatc aagcatatca attaaatctt
    21241 ctgtagaaat ttgcattcct ttagcaattt tttctattgt gtcataagat gggacaatgg
    21301 gctttttcga tttcggatgt tcattttttt caagcataga aatatatcct tttgttaaat
    21361 cagataattc acaaaaagca tccattgata atttatgctc tgttctatat gattttagca
    21421 attctcctaa cttcatttaa aactcctttc tatatattgt ttaatccatt atacatcttt
    21481 aaataaaaaa agtaaatttt tttgtttaac acacttgaca ttttgtgttt aacgtgttaa
    21541 actataatca agcttaagga aataacaaaa acaaaccgga gggaaacacc atgaacacat
    21601 taaacgagaa agcaatcaac atctttaaag cagtagctaa ggaaacttta atccaaggca
    21661 cttacgagga aaacttcctc tacagccaac ttgaaacatt cagtactaac tgccgtcaat
    21721 tcacttttgg atggacagag ttagcagatg agattgaacg ccaagagcgt taccttctcg
    21781 attctggttt cactcaagag gaaatcgatg acattcgttt cgatgcagcg ttcgcaggaa
    21841 tgcttgataa aatgaatgta gcctgattgg tatcaccaag gttcgaatcc ttggcaggtt
    21901 gttgctcata gagcgaaaaa agagagaaag gagtagaacg atgaatgaat cttttcttac
    21961 gatactaggc atatcaatga ttgctagttt tatcacgaat ttaattgctt acttagctgg
    22021 taagcatcat ctgaaaaaga aaattaaaaa ccacaaaatg tggtttgatt ctgagataga
    22081 gcgtatcaag aaaaagtatc atttgtgatt tttcttggat aattttttca taaattgttt
    22141 ttgaagatcg gaaggttgtt gcttgttcgc gaaatgacta agagtgctta tattttttat
    22201 tgctacatct gcagatattt ctcctgaaat agctttaaaa attaggtcat ttatctttaa
    22261 tccttggtcg gtttgagtgt ctagttgaga tactttttca agttcaagta atcttaattc
    22321 gtgagtttgt tgcagcgaat aaagttcttg tgagtgttgc ttttgcattt tttccatatc
    22381 ttgtttaaat tgattttcga cattttcaag ctcttgtgag tgtgcaatgt taattttatc
    22441 aatttcatgc ttgctgtttc ctttagcagc gatgtaagac cacatgccag aaacaaaggc
    22501 aggtatggca gcgatcgcaa gtgtttctat aaaactaaaa ttattcataa gatttctcca
    22561 atcgttttat tttgattata ccacatttga aaggtagtta gaattggaag ataaaatcat
    22621 tgaacttgct gattacttca tcagcgaaaa cacaacgtac agagaagcta aaatagcgtg
    22681 tgagaagcta tttcttcaag tcagtcatga gatagaactc agggcgctgg aaagtaagac
    22741 gagggggaac gataatggaa cagccgcatg ttaatgttga tatttctggt atggaaaaat
    22801 tagcagaagt aactcaagag gagactgaaa aaatattaac ttatgatgaa atcgtgttgc
    22861 taaaaccaat tactcatctt cataaatcta tctttaggca aacagaatac ttatcagagc
    22921 agttgactga aaggcttcat caccttgagg actacaatag tcccatagat gaagaaacaa
    22981 ttagattagc tgaggtgact atagaatttt ataatctact aatcaagtct cctagtatta
    23041 gtacagttgt caaggagatt gtgagcgagg gacataagag ttaaggcagt taaggcatca
    23101 tgaacgctat ctggattgta gtatttaagt ttatgtgctt tggaattacg ataaagatgt
    23161 gcgattgtca gaagtaaatt cttcaatcct ttatattcac tttgttcgtc gagagtttgt
    23221 aatttatttc cgttgataat catgatgggt tctttggttt taaaacattg gtctattaga
    23281 cttgctgagt ccagagacga accggttagc aaacgaatgc ggtgaaagat tcctttactt
    23341 gcttcaaata cagcatgaaa ataattttct tgtaagagtt cctgggtgca gaattttaaa
    23401 acatttggat gaacatttaa tgttctcaac atatgttcaa gtgattcaaa tcgtttcttt
    23461 gcctcaacta aagtttgtga agcagtagta ataactacat gtccgtcatc tgatatggta
    23521 aggcctttta gggaaagaac gacatttagt tttaatctta agttttcaaa atctgaaacc
    23581 gtatcgatgt acctcaaagg attgcagata tactcaatta caagtttgat atttgattta
    23641 tcttgtgttt tgttgagtat atcagacatg atattgtgaa ctctatggtg tttattgagt
    23701 ccagagttct ggtcgttttg gggatatcct aaaacttctc ccatccttgt gatttcagaa
    23761 tgtgaaacat aatcagatag tattttactg attgtatcta caaattgtgt atcaatactt
    23821 aacatagcaa acctcgtttt tattaaacat tatatcaaaa aggagaaaga aatgagacca
    23881 ataggatatc ggcttaatgt tgaagtttcg ggtattgaag aactaaagga agcctgtaaa
    23941 gaagtatcaa aaaaagccga agaattgcaa gaagcaatcg atcgacttag tattattgaa
    24001 tttgaattaa aagccaagcc tgtcaatgat tagaacaatc tatctagaaa cgacagggca
    24061 actattaaca caagggggtg agtgcgtgca aggagaacgt ttaagaaaat ggcgtgaaaa
    24121 agagaaaatg tctcaagagg aacttgcaga gaagtcaaat gtttctcgaa caacaataca
    24181 cttaattgaa tcaggtcagt cgtcaacagt gaaaattcga acacttcaaa aattagcagt
    24241 agtttttaat aagcaagtga aagatttttt ttaaagaaaa tgtttaacaa attaaacaaa
    24301 aaagaaagga gagcgtatga cagactttaa aaatttagat tgtcaattta tctttcaaga
    24361 atgcgactga aaattatact gctgttagta atagttttat caatgaccca aaactggact
    24421 ttacagctgt tggtattatg atggttgtcc tagctaacca cccaaattgg caagtctatc
    24481 cagatgaaat agctaaacga aaaggtgtta gtcgagacac agttgatagc tacttcaaaa
    24541 tattagaaaa aaatggctac ctacgaattg ttaaaaaagg catgggacgt ggtaaaggag
    24601 ttcgtgtttt cagatttttc tcagatgtaa aaatatccga ttttcaattt gaaatcatga
    24661 aacagagatt gaatgaaagt atatctaagt tatccacagg ttagaattta catttccgat
    24721 ttttacaaat ctgtatttta caaatctgta ttttacaaat cagaaaattt aggcactaat
    24781 aaatattaac taacaacaag tattaaataa caataaatat taaaagacaa ccagtcctac
    24841 ttctctaaat aaataaaaga gagggtagaa aaaataaata caaaggaggt gaggaaatga
    24901 gaccaagacg atatccgtat agtgggaaaa aagagtccac ctttgtaaag gcagaccctg
    24961 agttagttga aaaactttta agaaacacta gttttcttga gcgtttacaa aaaaagccta
    25021 tcaattttca gatagactca gaagaattta agcgtcttag ctatgaagcc attcatgata
    25081 cttctcaagt aactcaatag gaggaaggaa taaaaggaat actatgaacg aactcatcaa
    25141 cgtaaccctg aatgacaatc atgagcctgt tgtttccgga agacaacttc atgaagctct
    25201 gggagtcaaa acaaaatatg ccgattggtt caatagaatg attgaatacg gctttacaga
    25261 aaatcaagat tttttgcttc tcaaaaatga gcagcaaaca ggacgagggg gtcacaacaa
    25321 agttgaccac atcatcaagc tagacatggc caaggaaatt gctatgatcc agcggacgga
    25381 gagaggcaag caagtccgac aatactttat ccaagtagaa aaagacttta atagccctga
    25441 gaaaatcatg gcaagagcat tgctcatggc tgatcagaaa gtccacaagc tagaggctca
    25501 gattgaggct gaccgtccta aggtgctatt tgcagacgca gtaagtgcaa gccatacatc
    25561 tatcttggtt ggcgaacttg ccaagctcat tagccaaaac ggctacaaaa tcggtgccaa
    25621 tcgcctcttt tcttggatgc gcgaaaatgg ctacctgatt aagcgcaaag gctcagattg
    25681 gaacgtgcca acccaacgta gcatggactt gaaactcttt gaaatcatgg aaacaaacgt
    25741 gcaacacgca gatggacata tcactgtgaa caagacacca aaggtcacag gcaaaggaca
    25801 acagtatttt atcaataagt tccttaatca ggaatacttg acaggataaa aacaaaagcc
    25861 cctctggaac ggcaattcca ttgagggact aagcaaaata ctttacgagg taattatatc
    25921 atgaaaacag taaaaaagga atgggagcca cggattgtaa acatcatggc agatggttct
    25981 caagttgatg atttgacagg ctatgtcatc cctgctggtc attcgtacta tgacattatt
    26041 ttaggcatga acaagcaatc taacgaggag ggcgtagctt aatgaaatta cttactaaat
    26101 taaaactcag actcgaaggt gttattaaat cagtcaacct tgactggaga gaggttgcta
    26161 ttgaggttag caatgacctt ctcgaagagc gcaaacgtcg ctttatgcgt gagcaagaaa
    26221 accatgactt gaagcaggag cttgctgcct acaagtacaa agaaaacttt gatatcaagg
    26281 ctagactgca aggagaaatg tagatgtaca ttatatcgat ttatgtcaag aatactgaaa
    26341 ctggaaacga ggatttcagt ttgattggac gtgatttctt accgacgggg caccaagact
    26401 atattgcaag agtttttgga acaaaagaag aagcgattga ttacttaaaa tctatatctt
    26461 acatcgcatc aggtgttcat ggtaacgatt gggtttatca aaatgaaaaa ctaccagaaa
    26521 ttgagtcacg ttgccgaatt tggaaagtag gagaataaaa ggagaacaat atgtttaaag
    26581 cactaaaaac aatcaaaaaa atcaaacagc ttcagaaaga aatgcacgat gtcagtttag
    26641 cctttctggc tctacaagat gtcggattga tgctagagac tgaaagaagc aaggcgaagg
    26701 ctcaaacaat gcacgatgta agccacatgc tcaaggacgt cctgggcggc aagtcggtag
    26761 atgaagccat gaaacgtcta aatagcgaag tgaaaattga agatgtggag caggaagatg
    26821 actagaattg aacttgaaaa ccgtgtatgg cttttggcta atcatgaaga aaaaaaacga
    26881 attgctggat cttgggctaa cgtcaaagac cagatatgtg aagcgagttc tggaactagg
    26941 aaaggtgtat gctcatgttt gattacgaca gagacataat gcagcctcct gaacccagag
    27001 aagaacatga cccagctgat tggattttca gcgctggtca atggatctat gtaggagatt
    27061 gttagcctaa aggagaaaaa aatgacgcag atgaccaata aaggaaagtc gttcataaga
    27121 gcagagatct ctgaaaaaca aaaagaatat atcagacttc ttgctgaatt gagaggcgtg
    27181 acaacacaag aacttctagg tcaagttgta gaacgcttca ttgaccggaa tttgcaactt
    27241 attcaagatt acaaaaatga attagatgac ttaaatagta agtctagacg cagaattgac
    27301 atgaacacat aggagaaaac aagatgacta ataatcaatt agcaacacag acaaaacgta
    27361 acattactac tgacccaagt ttattgaccg gggcagacat caaaaagtat tttgacccac
    27421 aaaacctact gactgaaaaa caagtaggtc aggcgctagc cttgtgtaaa ggtcgcaatc
    27481 ttaacccatt tgctaacgag gtctacattg tagcttacac aaaccgtaat gggggcaaag
    27541 agtttagctt aattgtctct aaagaggctt tcttgaaacg tgccgcccaa tgtaaagact
    27601 atgagggctt tgaggctgga gtagtggtag tagacagtga gggtgttatg cacgaacgca
    27661 aaggggcaat catgctccca gaagatacac tgataggcgg atgggctaga gtgcaccgca
    27721 aaaatttcaa ggtacctgtg gaaatttttg tcagtcgtga ggaatatgac aagaaacaaa
    27781 gtacatggaa caccatgcca gctaccatga tcaggaaagt ggctctagta aatgctctta
    27841 gagaggcttt ccctgaggac ttggggaaca tgtacacaga ggacgacggt ggagagacat
    27901 ttgaccgtat caaagacgtc acacctcaag agagccgtga ggatgtcgta gcacgcaaga
    27961 tggctgaaat tgagcaattc aacaaagagc aagaggcaaa tcatgcagat cccgaacctg
    28021 ctcaaactga ggaaacaatc cagggcgaat tgctagacgg tgaacttgaa tattaggagg
    28081 acaacatgca agaattacag gttattgatg ataagaaaat caataaaatc tatgagatga
    28141 tcacaacgga tgaacttact agagagtctt ttgaaaaaga cctcatagag gctactgaga
    28201 agtacaagga ctatattcct acagctggaa ctctcaaaga cgacaaggca aagcgggctg
    28261 aatttaacaa gttaattgag tctaaaaatc gtatccgtat tgacactaaa aacttactat
    28321 cagagacagc taacacatgg gatagttatg ctaagtcaat tattgaccca tttgcaaccg
    28381 tagttagtga atttgacaaa ggtatcaagg aaatcgaaga acatcaaaga caactaaaaa
    28441 tagatacggt taagagttac ctagccaaca aatcagctga gtacatgttg gatcctcgtc
    28501 tctttgatga aaaggccctt gagtatgtca aggctggcga tttcatggca gatggcgtga
    28561 cgcttaaaaa agccactatg aagtcacttg atgacatggt cacatttgaa tttcagaaac
    28621 aacaagaatt tgaaaaagcc aagtcagcta tttcagggtt atgtgctgag tacggcatga
    28681 ctgactcacc ttacattaga cagctgaaag acttgactct tgctgaagtc tttgaacaaa
    28741 tcaaagctga ttatgagttt gaaaaacaaa aggaagaaat cagacaggct caagaacgag
    28801 cagagcgaga aagtcaggaa cttttagcag cccaacaaac caaacagcaa gaacgggctc
    28861 caaaatcaac gggaacccca aattttgacc cagaaacggg caaaatcttg gacggtggac
    28921 aaatcctcca aaatgagcct aacgctctta gaggggctga aaatgaccta aaacgatatg
    28981 cccaaaaaat gactttagag gtgtattttg tagacacagc cgaaaaagac cgtttcaagg
    29041 ctggtctaag tcaactcgga tttgatttta aaaagaacta tcaagtcagg ggttatcaac
    29101 gtatcgagcc attaactcag gctgaactaa atgaacaatg tgggtggtaa gtatgacaga
    29161 aattgaaaaa atttcagaag aattggctga atatggggtg cctgatgagt taataggaaa
    29221 aatagaggac ctattagcga ctctgtatgg cgaaaaaaag gaaattggag atagaaaaat
    29281 cttggatatt tctccagagt caatggggag gtaaccatgg acatcagaaa aatatctgac
    29341 agcgtagcca tctactcgga cggcaagaaa ttgcaggtta tccacaacct aggggatgag
    29401 tttatccttg atttcaatgt gggagaggat agcgtctgga acctcaatgg ccaagtcgta
    29461 gaaattattg acatgattga gcctgtcttt aaagttttca gcttttgctc aaaatctgga
    29521 gagggtatgc aacgcttaaa acatgctatc gtccactttg aaatatttga gcagtacatc
    29581 agagataatc aggaagacct gatgatctgg tggcacaatc caggagggga atatgattaa
    29641 aaccgtattt ttttcatgtg attatccaca tcatgaggtg attgacgacc aaataaatag
    29701 ctggcttgcc gaaaatccag gcattaagtt gattgacatc aaatttcaat caaatgtgtc
    29761 tgctgtcgct gacagtggag tcagtgctga atattggcat acatccgcat tgattattta
    29821 caaagttccc tcagagaaca atataagcag tattaattca aatggtttag gttttataat
    29881 cagctgtgag aaatgtggta gcttatcaat aatcaaggga aaagatgtag gtcaaaatgt
    29941 atgttatgaa tgcaaaggag agaaataatg aatgatttta tcaaagagat tgggatggct
    30001 atcctatgga tgtttttagg gtatctcttg ggagagcgta gcactagagg gggacaaatc
    30061 agatgatcaa taacgtcaca ctggttggga ggcttgtagc gcctcctgat ctacgaaaaa
    30121 cgcctaataa tgtatctagt ttacagggca cgcttgcagt caatcgcaat ttcaaaaacg
    30181 aaaatggaga gcgtgaggct gattttatca attttcaagc ttggagaggt acagctgaca
    30241 tcattgctca gtattgcagc aagggctcac ttattgggat cattgggcgc ttacaagtta
    30301 ggtcttacga gaaagacggt cagcgtcgat atgtgactga agtaatcgct gagagtgtag
    30361 ctctgctaga gagtcgcaac agtcagcacg gacaaggcaa cagtttccaa aatgggaata
    30421 gctcaccttt taccgatcct aacccctttg acctcccaaa tgacggtttg ccgttttagg
    30481 aggtatatat gtcaaaaatt aaaattcttg acgcttgctg tggcagtcgt atgttttggt
    30541 ttgataaaaa cgaaagtcac acaattttta tggacattag gcaagaaaca tttgagatac
    30601 atgacaaaaa ggtcaatgta gaccctgata ttatcggtga ttttcgtgac atgccttttg
    30661 aagacaacac atttaatcta gttgtgtttg atccaccaca tctaaaatgg gctggaccta
    30721 attcgataat gaaagctcag tatggacagc tggacaaagt tacctggtcg gaagatttgg
    30781 ccaagggttt tgaagaatgt ctgagagttc taaaagttgg cggcacacta gtctttaaat
    30841 ggtctgaccg tcagataaat gtaaagaaat tactagaggt gataccattc aagcccttat
    30901 ttggtcagca aagaggcacc acacactggc taacgtttgt aaagtttgag gaggacaaga
    30961 atggagtgga cggattgggt ggattggaaa cctgaaacca aaacggacat taaaaccaaa
    31021 attgaaaatg acgggtacac ttttccacac tatgacaaga aaaacaacgg cgtcaagtac
    31081 gtcatctcta cactggacat caaacgagac tgtctaagac ttggagtacc gtttgaagat
    31141 gtgtaccctt tgcaaacgac acttttttaa caggagaaag aacatggcaa gtaaaatcaa
    31201 tgcgacagaa cgtattgcta tcatcattga gaaacaaaaa atagaggtcg ttacgactct
    31261 aaactatgat atgagcatta gctttgataa caaagacacg gctcctacac tagatgacaa
    31321 tggtgacctt tttgaaccgg tctacaagtg caaagttaag gcaattccca aaaatgatgt
    31381 atttttcacc tcattaacac gggtcaagag caacatcaag acgctacaag aggttaaaaa
    31441 attctttgag ttcgtaaacg aaaacagaga aaatctcttt gagatggcag gatttaaggg
    31501 ggctcttgaa tgaaattgac cctgaacatt gagcctaaac ctcaatcacg gccaaggttt
    31561 gcaagacgtg ggagttttac cacaacttac gaagacaagg atatgaaaac atggcgcaat
    31621 cattgccagc tgctcattgc taatcagtac atgggtcagc ctatccttga gggagctttg
    31681 agggcacggc ttagatttta tatcaaacct cctcagtaca tttccaaggt caagaagaac
    31741 cagcaggccc tcctagatga aatcatccca gtaggcaaaa agcctgacat tgacaactac
    31801 gaaaaagccc tatatgacag tatgtcaggg atcgtattcc aagacgacgg tcagatagct
    31861 ctgcatgatg taggcaagtt ctacagctta aaccctcgca tagaggtaga ggtggaggtc
    31921 atggaatgga acgcatgagg cgagattatg actgagtatt tgaagaaatg aggaaattaa
    31981 gatgacaaaa actatcgaac taccagacta ttatgaaccc gattggggaa atgcaagata
    32041 cggaacatta gaagaactaa aagagctgtt gctctataag cgtatcgtgg aatgggataa
    32101 agatttttta ctacttgaag atgggacaaa agtcactatt gaaatgtctg aaagtgattg
    32161 ctgtgcctca gcaggtgggg agtttcaaaa tgtttcactt gacgctgtaa tcactaatgt
    32221 tgaaattgga gaacaggaag aaatccctga ccattgggga gcgggttata aaaacaaagt
    32281 aaccatcttc cacaatcaaa atcctgtagc tatcgctaac tgtgaggcag aacataatgg
    32341 ctattattat agcgtgggct ctctagtgat tggtgatatt catttcccag tagtccatgc
    32401 ttaggaggct gatatgagaa ttaagacgga aagcggagga gttggaagat gatggaagag
    32461 ttaaagcaaa aagttaatga agtatacaac tggacggtag aagacgggaa gccgcaacct
    32521 cccaagcaag atttaccaca agcagtgaaa gaccgggcgg actatttttg ggaaatggca
    32581 gaagatggta tgacgtttat gggagcgatg gaatgcatct tcgctgatga aaagcctacc
    32641 gactatgatt tgggagctac taagggttgg ttgccaaaat ctaaggagtt tgatgattgg
    32701 gttggctatt cgccaagcat gtctcagtta gttattgcag tttatttgat ttacagagga
    32761 agcgaagatg aaacttaatg aattgattaa gaaatataaa aaacttgagg gtgtatggaa
    32821 tgctgaagga gcagaactag ctcgtcaaat ttttctgcaa gacttggaac aactagacga
    32881 atccgaaata ggttacgcag atgaagctcc acgctacgta aagaacatac tagcacgatt
    32941 gcgagaattg ccattgcatg atagagaggt ttggttaaag gctatcatga gcgaatttga
    33001 acaggatttt agccgtgcaa aatggcgaga gggctacgag caaggtaaaa ttgagggtat
    33061 ggttgaacgt gaaaaagtca aagttccgcg gtttgtggct gaatggattg aggaagctag
    33121 aaaagcttgt aaagacgtgg tagaattatt cgaatttgat ttcacgaacg atgaagttag
    33181 aaaatggttt atgcaagaaa gaccatttga tttagtagct agagcatggc ttgacggcta
    33241 cgaggtcgag gaagagaagc ggtatttggt gactttaaaa aataggcagc ctttggtcaa
    33301 atcgcaatca gggagtactc tttattttag tcaagatata acagctagga attataaagg
    33361 tactcaaaaa gaactagaag aagctggcct cggatgggtg ttcgattgtg aaggtgttga
    33421 gattgaggag gtggagtgat gacacaaaca gctgaaagtt gcttagaaga aacttatgaa
    33481 gtcatcaagg accgcaaagg taagatgatt gacggggtgt ttgttaaaga agagtattat
    33541 ggagaataaa gatgccaaat tttgcagaag gaacaattaa actaagagga catgcagaaa
    33601 atattaaatc ggctttgaaa tatatgtttg aagctgctgg tgatgtcaca atcgaagaag
    33661 atacagatgg tgagctaatc attttcactt catcaaactc ttatttttac atcaatggca
    33721 caaaacgtgc ttttatcgac ggtgaaagtt ttgaaattca tcttgatgat gattttctta
    33781 tcatcgagct taataatttt acgcaggcat ggcgcgctat cccagacaat tacatagaaa
    33841 tctctgaaaa atttaatgtt gacattaaaa tctttacatt tgaacagggc ttggaattca
    33901 ctcaagaaat cgaaatttca aaagggaaaa ttttaaaaga cattgtattg aagtatggtg
    33961 attatagatg ggaagtcgca tttagcaatt tagggggatg aacagaagga ggatttggca
    34021 tgataccgaa atttagaggg ttatccattg acgaaaaaag caaaggagaa tggcaatacg
    34081 gacatttaat tgaagataga ggaagagcat ttattatcag cgaagtggta gaagccaatg
    34141 aacaatacat tactataggt tcttggtgtc ctgtaaatcc agcaacatta ggacaatcaa
    34201 caggactcag agacaagaac ggcaaggagg tttttgtcgg agatattatc aaatgcacaa
    34261 gaggatgcct tcacgaagtc tatatagaaa aagaatatgg cggtacgtat tttggaggaa
    34321 tgccagctgt atacctaaaa gacttgagag aaggatatgc gtggactgag catgaagaaa
    34381 tcatcggcaa catctacgaa aatccggagc ttttggaggt caacgagtga gatattttaa
    34441 aatcctatgt attgttttat tcgcatcctt actcgtagca tgtcaccaga tttcgagtgg
    34501 gacagtggta gataagtaca ttgatgaacc tcacacaacg ttcatacctg ttataaatgg
    34561 taaaagttcg gtacttgtgc caaccagaac caaaagaaaa tacattctgg tcatttcagg
    34621 atatgcaggc aataagcaag ttgaagaaag gtttgaagtg acagcaaatg aatacaagca
    34681 ctatgaaatt ggcaatactt ttatacagga tgccgtttta gaaaataagg aggaggataa
    34741 ggaatgaaac caaaaaaata tccgtattca ggaaaaatgc aaaaaatccc gtcgccaata
    34801 ttttctgcac gaccaatttt taacgaggtt ccaattgtag aagaagttaa ggttgagttc
    34861 ggagttgaag ctagtatggg gcgcatatat ccagaaacgt taatacattt agatatttct
    34921 ggatacggaa atagagtgca ttcagtacat cgcttccccg gtattttact gagtgttggt
    34981 gagtcaatcc aactaaagat gcttttctat aaaagactta gaaattttac tacagatcgt
    35041 ttcttgacgt ttagagaatc tgattggaag ttctttatcc gggacctggt caacgaattt
    35101 gtgcgataaa aaagccaaga cactctctgt ctcggctaaa ttcctaataa gactattata
    35161 tcacaaagga gacagagagt gaacaaggct aaagaactat tgaaagagtt gcagaatctg
    35221 gacatggaca ttcaaagccg tatagatgaa attaacgagc ttgaggcagg tttgctctca
    35281 agccccaagt ggattgacgt caaagtccaa ggtggtcaag ctagaaaagt tgatgatgtc
    35341 tatactcagc ttgtcgtgat gaaagaggcc atagaacagg atactaaaga ggttatcaac
    35401 agaaagcttg agcttggtag gttgattaac aagctgaaaa atccaaagag caggtctatt
    35461 ctcagggtga cttacattac taagatgtat gttgatgata tttgtgacaa aatggaaatc
    35521 agcagaacaa ctttctacac ttggcggaat atggctatct ctgaactgaa tgaggttttg
    35581 gagagaatgg aactaaattg aactttacaa aaccgtacgg gaaaaaatga tacttgttag
    35641 cacagttttg taattctgat aaaatggtag tatcaagaat tgaaaagaga ggtctcagaa
    35701 ttggtagatg gttacctgta atgtcagggg gctgtaatgg ccttggaggt tcaagtcctc
    35761 ccctctcctt tgagtgtttg tgtcccagaa tgagttaaat cttctgggtg gggattcaca
    35821 tatcactcat taactcctat cactcattaa cttaaaaatg gttgcggagg cgactggacc
    35881 tcgcatgatt gcgtagctaa ttatattccg gataagttat aagctagagg gtttgattcc
    35941 ctcagaggtt ttaaagacta caaaaaataa aaaagaagtc aaaatttaat acgcacgcaa
    36001 ggtagtagtc gccttgcaag aaggtcgcac atcgtgtggc tttttttgat tattcgaagg
    36061 gtggtgatgg aaaattgagt ggattgagaa taaaacaaaa gagatttgca gatgagtaca
    36121 tcatctcagg taatgcgacg gaagcctata agaaagcagg ttatcgtgtt tctagtgata
    36181 gagtggcagg cgttgaagga cataagttac taaagaatcc taagattaaa agctatatag
    36241 atgaacgact gaaacagctt gattctgaaa aaatcgcaga ccagcaagaa gttcttagtt
    36301 atctaacttc agtgatgcga ggagagacgc aagagcagac cttgataagc attggagaac
    36361 tagggcagac gattacggat atagacgtag gagctaaaga tagaatcaag gcggctgaac
    36421 ttcttggtaa acggcatagg ctttggacgg ataaggtaga ggcgga
//
LOCUS       DAVKZI010000019        35897 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKZI010000019 DAVKZI010000000
VERSION     DAVKZI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.019"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            25..1956
                     /locus_tag="VXB18_001120"
     CDS             25..1956
                     /locus_tag="VXB18_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0382333.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKV
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            1943..3259
                     /locus_tag="VXB18_001121"
     CDS             1943..3259
                     /locus_tag="VXB18_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0382334.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            3434..4420
                     /locus_tag="VXB18_001122"
     CDS             3434..4420
                     /locus_tag="VXB18_001122"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0382335.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENIAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4484..4555
                     /locus_tag="VXB18_001123"
     tRNA            4484..4555
                     /locus_tag="VXB18_001123"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4517..4519,aa:Arg,seq:ccg)
     gene            4738..5436
                     /locus_tag="VXB18_001124"
     CDS             4738..5436
                     /locus_tag="VXB18_001124"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0382336.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRETILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5427..8966
                     /gene="smc"
                     /locus_tag="VXB18_001125"
     CDS             5427..8966
                     /gene="smc"
                     /locus_tag="VXB18_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0382337.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKDRTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDEMARLIESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLATIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8963..9757
                     /locus_tag="VXB18_001126"
     CDS             8963..9757
                     /locus_tag="VXB18_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0382338.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYI
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            9757..10575
                     /locus_tag="VXB18_001127"
     CDS             9757..10575
                     /locus_tag="VXB18_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0382339.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10579..11868
                     /gene="ftsY"
                     /locus_tag="VXB18_001128"
     CDS             10579..11868
                     /gene="ftsY"
                     /locus_tag="VXB18_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0382340.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11912..13399)
                     /locus_tag="VXB18_001129"
     CDS             complement(11912..13399)
                     /locus_tag="VXB18_001129"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0382341.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(13548..14288)
                     /locus_tag="VXB18_001130"
     CDS             complement(13548..14288)
                     /locus_tag="VXB18_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0382342.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14288..16453)
                     /locus_tag="VXB18_001131"
     CDS             complement(14288..16453)
                     /locus_tag="VXB18_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0382343.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQSQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16623..17576
                     /locus_tag="VXB18_001132"
     CDS             16623..17576
                     /locus_tag="VXB18_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0382344.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLEFIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            17653..19641
                     /gene="uvrB"
                     /locus_tag="VXB18_001133"
     CDS             17653..19641
                     /gene="uvrB"
                     /locus_tag="VXB18_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0382345.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDVNSLNKQE
                     RKDLVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            19664..20131
                     /locus_tag="VXB18_001134"
     CDS             19664..20131
                     /locus_tag="VXB18_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0382346.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFVESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYRATEFSGTLQS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(20128..20214)
                     /locus_tag="VXB18_001135"
                     /pseudo
     CDS             complement(20128..20214)
                     /locus_tag="VXB18_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
     gene            20445..21421
                     /locus_tag="VXB18_001136"
                     /pseudo
     CDS             20445..21421
                     /locus_tag="VXB18_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000207598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            21418..22329
                     /gene="rbsK"
                     /locus_tag="VXB18_001137"
     CDS             21418..22329
                     /gene="rbsK"
                     /locus_tag="VXB18_001137"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEV0382347.1"
                     /translation="MSKIVVVGSISMDLVMRTKRIPEGGETIFGDSFNIVPGGKGANQ
                     AVAIGRLSSVEDNIYIFGNVGEDIFSADLLSNLQNNDISTAYVGTVPQSTGVAQITLY
                     GGDNRIIYYPGANNLVKTNDWKNEWKLLSDASIVVLQNEIPHEANLSIAKFCQENQVK
                     VLYNPAPARETDKEMIPFCDFITPNEHECSELFPDKKLEEIIKIYPNKMIVTLGVEGS
                     IYYDGTAVKKIPAIKAEVVDTTGAGDTFNGAFAYAISKGKEMNVALSFATIASHLSVQ
                     RFGAQGGMPSLKEIKEHSGYEEIWDFK"
     gene            22304..22702
                     /gene="rbsD"
                     /locus_tag="VXB18_001138"
     CDS             22304..22702
                     /gene="rbsD"
                     /locus_tag="VXB18_001138"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEV0382348.1"
                     /translation="MKKYGILNSNIAKLADDLGHMDWVCIGDLGLPVPKGVDKIDLAL
                     RKGSPSFLEVLKEYSDHVLIEKIFLAEEIKEQNTEQWQAVLDLLGSNIIIEYISHEEL
                     KAMNTKVKAVIRTGEDTPYSNIILQSGVII"
     gene            22716..24194
                     /locus_tag="VXB18_001139"
     CDS             22716..24194
                     /locus_tag="VXB18_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEV0382349.1"
                     /translation="MKIEMKNISKSFGNNRVLESIDLVLNSGEVHALMGENGAGKSTL
                     MNILTGLFPATSGTIFIDGKEKTFSNPQEAERFGLSFIHQEMNTWPDMTVLDNLFLGR
                     EIKNSIGFLDKASMEKKAKEAFKRLNISIPLDAIIGQLSVGQQQMIEIAKCLLSEVSL
                     LIMDEPTAALTDRETETLFKVIEGLKSDGVGIVYISHRMEEIFKITDLITVMRDGFVI
                     DTKKTKLTNADELVQKMVGRELEDYYPEKKAEIGNIVFQAKNLSGNSFTDVSFYVRQG
                     EILGFSGLMGAGRTEIMRAIFGIDSLKSGQIIINEEELIIKNPFEAIKHGIGFLTEDR
                     KDEGLILDFSIKDNMTLPSTRDFVKNGIFDNKTSDIFVQRLIDRLQIKSGYPDKEVGT
                     LSGGNQQKVVLAKWIGIAPKVLILDEPTRGVDVGAKREIYQLMNELAERGVPIIMVSS
                     DLPEVIGVSDRIMVMHEGRISGELTRQEATQEKVMQLATGGQ"
     gene            24196..25137
                     /gene="rbsC"
                     /locus_tag="VXB18_001140"
     CDS             24196..25137
                     /gene="rbsC"
                     /locus_tag="VXB18_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771495.1"
                     /note="functions to transport ribose at high affinity;
                     forms a complex with RbsA2C2B; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HEV0382350.1"
                     /translation="MKNTMKYMSELTTVIALIILMAVITIINSNFLTANNLLNLLLQV
                     TSNALIAFGMTFVILTGGIDLSVGSILALSSALTAGLLGSGMPVTLAILISLILGCIL
                     GMMNGLLISYGKLAPFIVTLATMTIFRGATLVYTNGNPITKGLSDTFLFQFLGQGYIV
                     GIPFPVIIMFIVFIVLYVLLHKTAFGKSVYAIGGNEKAAYISGVKLNKVKIIIYSISG
                     IMASISGLIITSRLSSAQPTAGASYEMDAIAAVVLGGTSLSGGKGRILGTLIGALIIG
                     VLNNGLNIIGVSAFWQQVVKGVVILIAVLIDRFKVVK"
     gene            25245..26210
                     /locus_tag="VXB18_001141"
     CDS             25245..26210
                     /locus_tag="VXB18_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0382351.1"
                     /translation="MKIIKKISIFALFVTFIFALVACGKTGLGNSSNDNKSTTQKSAK
                     ELKLGVSISTTNNPYFVAMKDGLEKAAGEKEVTLKIADAQDDAARQADDIQNFISQNV
                     DALLINPVDSDAIVTSIKAANNANIPVILIDRGSNGGEVLTTVASDNVEAGKMAAEFI
                     TKQLGEKAKTFELSGVPGASATVDRGKGFEQISKTNLDVLSSQSANFDRAKALNTAQN
                     MIQGNKEVQAIFAQNDEMALGAAQAVKAAGLSNVLIVGIDGQPDAHDAIAKGDITATI
                     AQQPAKMGEIAIQSAIDHYQGKKLEKETVSPIYLVTKDNVDQHNW"
     gene            26285..26428
                     /locus_tag="VXB18_001142"
                     /pseudo
     CDS             26285..26428
                     /locus_tag="VXB18_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            complement(26425..26940)
                     /locus_tag="VXB18_001143"
     CDS             complement(26425..26940)
                     /locus_tag="VXB18_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0382352.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLTIVDNGGRVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(26952..27479)
                     /locus_tag="VXB18_001144"
     CDS             complement(26952..27479)
                     /locus_tag="VXB18_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0382353.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHIVFGTLGALYLRKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVVFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(27761..28324)
                     /locus_tag="VXB18_001145"
     CDS             complement(27761..28324)
                     /locus_tag="VXB18_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0382354.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(28308..28859)
                     /gene="coaC"
                     /locus_tag="VXB18_001146"
     CDS             complement(28308..28859)
                     /gene="coaC"
                     /locus_tag="VXB18_001146"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0382355.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(28871..29560)
                     /gene="coaB"
                     /locus_tag="VXB18_001147"
     CDS             complement(28871..29560)
                     /gene="coaB"
                     /locus_tag="VXB18_001147"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0382356.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNSTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            29790..31460
                     /locus_tag="VXB18_001148"
     CDS             29790..31460
                     /locus_tag="VXB18_001148"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0382357.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            31788..32963
                     /gene="mutY"
                     /locus_tag="VXB18_001149"
     CDS             31788..32963
                     /gene="mutY"
                     /locus_tag="VXB18_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0382358.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNIMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            33018..33722
                     /locus_tag="VXB18_001150"
     CDS             33018..33722
                     /locus_tag="VXB18_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382359.1"
                     /translation="MKKILIVDDEKPISDIIRFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            33715..35064
                     /gene="vicK"
                     /locus_tag="VXB18_001151"
     CDS             33715..35064
                     /gene="vicK"
                     /locus_tag="VXB18_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0382360.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            35066..35875
                     /locus_tag="VXB18_001152"
     CDS             35066..35875
                     /locus_tag="VXB18_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0382361.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT        11274 a         6151 c         7851 g        10621 t
ORIGIN      
        1 tcattagtaa aaggagttag attgatgaat aaaagaaaag ttagtttaga agatttttat
       61 aaatggtata gtctaaataa agaagagtta ttaaataagg caactgttgg tgaaaagttt
      121 aatgataaat taaaagaaga gtttctccag gaatggcctt tggataggat tttaacaatg
      181 tcaatcgatg aatatgtaat aggaaaggga cagcaaaata agtctttatg ctacgctctt
      241 gagaagggaa aatacaaaaa tctatttctt ggaatttctg gtggctcagc ttcaaaattt
      301 ggtatttatt ggaataaaaa aacaaacaaa tataaagatc aagctaataa tgagatttca
      361 gagttggatc agcgattttc aaaattaaaa tcagatttgt atgaaattat caaagaaggt
      421 attcgtttta actttgaaaa tcctattttt gatatgaaaa gatcaacaaa tgaatttatt
      481 ggtcgttctg ctatggtgac aaaattactt tgtatctatt ctgagggaga tcctttcttt
      541 ggtgtaaata ttaatagtca gaaagaattt tggaaccact ttgtttctca gacaaatcaa
      601 ggtggacctt atctgcaaaa tcataaaata attgaactgg tgtccaaaac ttatcctgag
      661 ttggagccat cgaaagtagg aactatgctt tttgagtatt ctaagctttt tatggaaaat
      721 aaggaagaca atagtacaat ggattcatca aacaattttc gtcatcaatt aactcaatct
      781 ctattaaagt ctccaaacct tatccttcgt ggtgctcctg gcacaggaaa gacttatctt
      841 gctaaagaaa ttgccaaaga attaacggat ggcaacgaag accaaatcgg atttgtacaa
      901 tttcacccat catatgatta tacggatttt gtagaaggtt taagaccagt atcaaatggg
      961 gatggagcta ttgagtttag gctacaggac ggtattttta aagatttttg tcagaaagca
     1021 aaagaaaccc aattgattgg aggacaagat aattttgatg aggcttggga ttcttactta
     1081 gaatatataa atgttgctga agaaaaagaa tatataacaa aaacatctta cttatctgtt
     1141 aatagtagac aaaatttgtc agtaaattat gatagtggtg ttccaggatg gtcactacct
     1201 agcaaatatg tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa
     1261 agtggtggaa aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt
     1321 tccccaacag aaattgatac tgataagaaa ttcgtcttca tcatcgatga aatcaatcgt
     1381 ggggagattt ctaagatttt tggcgaactc tttttctcta tcgaccctgg ctatcgtggt
     1441 gaaaaaggaa gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat
     1501 atccccgaaa atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc
     1561 tttgattttg ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt
     1621 ggcatgttgg ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac
     1681 ttgaacgctg ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt
     1741 tattttctta agttgaagga tgtagatttt gactatgaat tactctggtc tgattatatt
     1801 aagcctctcc tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact
     1861 ttgaaaaaag catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac
     1921 aatgaaggtg atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga
     1981 aaaatttgtt gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag
     2041 tctatcccaa gatgaacgta ttttcatttt tccaaatgat ttgactcata ctcctgattt
     2101 ggataaggac caaaagattt ttgaaacagt caatcagaaa atcaagacag ggaacgtgat
     2161 tggttttctt ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag
     2221 taatgaccat tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt
     2281 agatgttgct ttgtctcgtg aagagaggct ttatcaactt ttggtgtatc tctttcccaa
     2341 gtatctacaa gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa
     2401 cgacagtcat gttaagggag tgattgatgt aagaaaccat ctcaagaaaa atcttccttt
     2461 cacgggaaat attgcctacg caacgagaga gttcacctat gataatcccc tcatgcagtt
     2521 ggtccgtcac actattgaat acattaagaa tcagaaaagc attggtcaag gggtactaga
     2581 taatctctca actagtcgtg aaaacgtatc tgaaatcgtg cgtgtaacgc cctcttataa
     2641 actagctgat cgtgctaaga ttattcgggg aaatcaatct aaacctatac gtcatgcata
     2701 ctttcacgag tacagaaact tacaagaact ttgtctgatg atcctaaacc aagaaaagca
     2761 cggtttaggg tatcaagatc aaaaaatcta tggtattctc tttgatgttg cctggctttg
     2821 ggaagagtat gtttacacct tgttgccaaa aggttttgta catcccagaa ataaggataa
     2881 gacggatgga atttcagtat tttctgttgg gaaacgaaaa gtatatccag atttttatga
     2941 cagagaacga aagattgttc tagatgcaaa atataaaaaa ctggaattga ctgaaaaagg
     3001 aatcaaccgt gaggacttat tccagctgat ttcctattct tatattttaa aagctgagaa
     3061 ggctggactt gtttttccga gcaaggacaa ggttattgat aatgagatgg gaaacctagc
     3121 aggttatgga gctttgttga agaaatggtc tatccaaatt cctcagaagt cttcatctta
     3181 tagtgcattt tgtaaaatga tggaaaattc agaagaaaat tttaaagcga ttattgatga
     3241 agaagtgggg agaaaataat ttcctctctt tcttttattt ttaacacaag taaaacccga
     3301 acaatatatt tcaattcata aaataatttg acaaaaactg tactttggtt tataataaat
     3361 taaggaaacg tcggaaaagg cgtagtgatg caagagcata ggtaggtcat tacaaaagaa
     3421 acgagacatc gatatgttaa atgaatttcc aatttttgat tacgaagata ttcaattgat
     3481 tccaaataaa tgtgtcatta aaagccgtgc agaagcggat acaagtgtca ctttaggaaa
     3541 tcacaccttt aaactacctg ttgtgccagc gaatatgcag acgattttgg atgaaaatat
     3601 agcagagcaa ctggctaaag gtggttactt ctacattatg caccgttttg atgaggcagg
     3661 acgcattcct tttattaaac gaatgcacga tcaagggctc attgcttcca tatctgtcgg
     3721 tgttaaggac tatgagtatg attttgttag ccagctcaag gctgatgctc ctgagtatat
     3781 cactattgat attgctcatg gtcatgcgga tagcgtgatt tctatgattc aacacatcaa
     3841 gaaagaattg ccagatacct ttgtcattgc tggaaatgtg ggaacaccag aagctgtgcg
     3901 tgaattggaa aatgctggtg cggatgctac taaggtcgga atcggtcctg gtaaggtttg
     3961 tatcacaaag gttaagactg gttttggtac aggtggttgg cagttggctg ctctacgctg
     4021 gtgtgccaag gctgcgcgta aaccgattat cgctgatgga ggaattcgta ctcacggtga
     4081 tattgccaag tctatccgct tcggtgctag catgatcatg attggttccc tctttgcagg
     4141 acacattgaa agtccaggga aaacgattga agtcgatggt gaacagttca aagaatatta
     4201 tggttcagcc tcacaatatc aaaaaggtgc ttacaaaaat gtggaaggca aacgtatctt
     4261 gcttcctgct aaaggtcatc tgcaagacac tttaactgag atggaacaag accttcaaag
     4321 tgctatttct tatgcaggtg gacgtcaggt tgctgacctt aaacacgttg attatgtgat
     4381 cgtgaaaaac tccatctgga atggggatgc ttcccactaa gacggggtct ttgaccaaaa
     4441 aacttgttat tagagcaaat ttctgttata ataaaacaag tttccaccct tagtgtaatg
     4501 gatatcacgt aagattccgg ttcttgagat gggggttcga ttccctcagg gtggatgtaa
     4561 acatcctaaa aagcctttaa tagggctttt ttctttatcc tgacccaaat ttgccgctaa
     4621 aactgagaat ctctgtctaa agaattccca aatgctttcc agtcccgttt tagagtgact
     4681 cagggggctt tttttgatat aataaaaagg actattatca gttagaaaga ggttggtatg
     4741 aaagaattac aaactgtact aaagaatcat tttgcaatcg aatttgcaga caaaaattta
     4801 ctggaaactg cctttactca tacgagttat gccaatgagc accgcctctt aaaaatttca
     4861 cacaatgaac gcttggaatt tttaggagac gctgttctac agttattgat ttcagaatat
     4921 ctatataaaa aatatcctaa aaagcctgaa ggtgacctat caaaactccg tgctatgatt
     4981 gtccgtgagg agagtttagc tggttttgcg cgtgattgcc agtttgacca gtttatcaag
     5041 ttgggtaaag gggaagaaaa atcaggtggt cgcaatcgtg aaaccattct tggtgatgcc
     5101 tttgaagcct ttcttggtgc ccttcttttg gataaggatg tggccaaggt caaggaattt
     5161 atctaccaag ttatgattcc taaggtagaa gcaggcgaat ttgagatgat tacagactat
     5221 aaaacccatc tccaagagtt acttcaggtc aatggtgatg tggctattcg ttatcaggtg
     5281 atttctgaaa cagggcctgc tcacgataag gtctttgatg tagaagttct tgttgaaggt
     5341 aagagcatcg gtcaaggcca aggtcgttct aagaaattag cagagcagga agctgccaaa
     5401 aatgccgttg agaaggggct ggattcatgt atttaaagga aatcgaaatt caggggttca
     5461 agtcttttgc tgataagacc aaggtcgttt ttgaccaagg tgtgacggca gttgttggac
     5521 ccaatggatc tggaaagtcc aatattacag aaagtctgcg ttgggctttg ggggagtcta
     5581 gtgtcaagag tctccgtggg ggcaagatgc cggatgtcat ctttgctgga acagaaagtc
     5641 gcaaaccgct caattatgct tctgtagttg tgactctgga taatcatgac ggatttatca
     5701 aggatgcagg tcaagaaatc agggtggaac gccatatcta tcgtagtgga gatagcgaat
     5761 acaagattga cggcaagaaa gtccgtctgc gtgatattca tgacctcttc ttggatactg
     5821 gattgggacg agattccttc tctatcattt cccaagggaa ggttgaggag atttttaatt
     5881 ctaagcctga ggaacgccga gctatttttg aagaagctgc aggagtttta aaatacaaga
     5941 ctcgcagaaa agaaaccgag agtaaactgc agcaaactca ggataatctg gaccgcttag
     6001 aggacattat ctacgagttg gataatcaaa tcaagcctct tgagaagcaa gctgagaatg
     6061 cccgtaagtt tttagacttg gaaggacaac gtaaggctat ttatttagat gttctggttg
     6121 ctcaaatcaa ggaaaataag gctgaactag agtcgacaga agaagagttg gctcaggttc
     6181 aagaactctt gatgagttat taccaaaagc gtgaaaaatt agaagaagaa aatcaaactc
     6241 ttaaaaagca acgccaagat ttacaggctg aaatggccaa agaccaaggc agtttgatgg
     6301 acttgactag tctgattagt gatttagaaa gaaaattagc cctatcgaaa ctggagtccg
     6361 agcaagtggc cttgaatcaa caggaggcac aagcccgttt ggctgctttg gaggataaga
     6421 gaaattcact cagcaaagaa aagtctgata aagaaagctc tttagctctg ttagagggaa
     6481 atctagtcca aaataatcaa aaactcaatc gtttagaagc tgaattgctg gctttctcag
     6541 acgatcctga tcagatgatt gagctcttac gtgaacgctt tgtagctctt ttacaagaag
     6601 aagcggatgt ctcaaaccag ttgacccgta ttgagaatga gttggaaaat agtcgtcagc
     6661 tttctcaaaa acaagcagat caactagaaa agctgaaaga gcaattagct atagctaaag
     6721 agaaggctag tcagcaaaag gaagagcttg aaactgccaa ggagcaggtt cagaaattat
     6781 tggctgacta ccaagctatt gccaaggagc aagaggagca gaaaacttcc tatcaagctc
     6841 aacaaagcca actctttgac cgtctggata atctcaaaaa caagcaggcc agagctcaaa
     6901 gtttggaaaa tatcctgaga aatcatagta acttttatgc aggtgttaag agtgttctcc
     6961 aagaaaaaga tcgcctaggt gggattattg gtgcagtcag tgagcatctg acctttgatg
     7021 tttattatca aactgcccta gagattgcct taggggcaag tagccagcat atcatcgtag
     7081 aagatgaaga gtcggcaacc aaagctattg atttccttaa acgaaacaga gccggtcgtg
     7141 caaccttcct tccgttgaca acaatcaagg atcgtacgat ttctagccag aatcaagatg
     7201 ctatcgctgt aagtccaggt ttccttggga tggcagatga gttggtgact tttgatacta
     7261 gactggaagc cattttcaag aatttgctag ctacaacggc tatctttgat accgtggagc
     7321 atgcgcgtgc agcagcgcgc caggttcgtt atcaggttcg tatggtgaca ttggacggaa
     7381 cagagctgcg cacaggtggt tcttatgcag gtggagctaa tcgccagaat aacagtattt
     7441 tcatcaagcc agaactggag caattacaaa aagaaattgc tgcagatgaa gcaagcttgg
     7501 gttcagaaga agcggctttg aagaccttgc aagatgagat ggccagattg atcgagtcat
     7561 tagaagctat taaatctcaa ggagagcagg cacgcattca ggagcaaggc ttgttcctcg
     7621 cttatcagca aactagtcag caagttgaag aactggaaac tctttggaaa ctccaagaag
     7681 aggaaataga tcgtctttcc gagggagatt ggcaagcaga caaggaaaaa tgccaagaac
     7741 gccttgctac tatcgccagt gacaagcaaa atctggaagc tgagattgaa gagattaagt
     7801 ctaacaaaaa tgccatccaa gaacgctatc aaaacttgca ggaagagcta gcgcaagctc
     7861 gtttgcttaa gacagaactg caagggcaaa aacgttatga agttgctgat attgaacgct
     7921 taggcaagga attggacaat cttaatatcg aacaagaaga aatccagcgc atgctccaag
     7981 aaaaagttga caatcttgag aaggttgata cagaattgct cagtcaacag gcggaagaat
     8041 ccaaaactca gaaaacaaat ctccaacaag gtttgattcg caagcagttt gagttggatg
     8101 atatagaagg tcaactggat gatattgcca gtcacttgga tcaagctcgc cagcagaatg
     8161 aggagtggat tcgcaagcaa acacgtgctg aagccaagaa agaaaaggtc agcgagcgct
     8221 tgcgccatct acaaaatcaa ttaacagacc agtaccagat tagctatact gaagcactag
     8281 aaaaggcaca tgaattggaa aacctcaatc tggcagagca agaggtgcag gatttagaga
     8341 aggctattcg ctcattggga cctgtcaact tggaagctat tgaccagtac gaagaagttc
     8401 acaaccgtct ggactttcta aatagtcagc gagatgatat tttgtcagcg aaaaatctgc
     8461 tccttgaaac cattacagag atgaatgatg aggtcaagga acgctttaaa tcaacctttg
     8521 aagctattcg tgagtccttt aaagtgacct tcaagcagat gtttggcgga ggtcaggcag
     8581 acttgatatt gactgagggc gaccttttaa cagctggtgt ggagatttct gttcaacctc
     8641 caggtaagaa aatccagtcg cttaacctca tgagtggtgg tgaaaaagct ctatcggctc
     8701 ttgccttgct tttctccatt attcgtgtca agaccattcc ttttgtcatc ttggatgagg
     8761 tggaagctgc gctggatgaa gccaatgtta aacgttttgg ggattacctc aaccgctttg
     8821 acaaggacag ccagtttatc gtcgtaaccc accgtaaggg aaccatggca gcggctgatt
     8881 ccatctatgg agtgaccatg caagaatcgg gtgtttcaaa gattgtttca gttaagttaa
     8941 aagatttaga aagtattgaa ggatgacaat taaactagta gcaacggata tggacggaac
     9001 cttcctagat gagaatgggc gctttgatat ggaccgcctc aagtctctct tggtttccta
     9061 caaggaaaaa gggatttact ttgcggtggc ttcgggtcgg ggatttctgt ctctggaaaa
     9121 attatttgct ggtgttcgtg atgacattat tttcatcgcg gaaaatggca gtttggtaga
     9181 gtatcaaggt caggacttgt atgaagcgac tatgtctcgt gacttttatc tggcaacttt
     9241 tgaaaagctg aaaacgtcac cttatataga tatcaataaa ctgctcttga cgggtaagaa
     9301 gggttcatat gttctagata cggttgatga gacctatttg aaagtgagtc agcattataa
     9361 tgaaaatatc caaaaagtag cgagtttgga agatatcaca gatgacattt tcaaatttac
     9421 aaccaacttc acagaagaaa cgctagaagc tggtgaagct tgggtcaatg ataatgtccc
     9481 tggtgtcaag gctatgacaa ctggctttga atctattgat attgttctgg actatgtcga
     9541 taagggtgta gctattgttg aattagctaa aaaacttggc atcacaatgg atcaggtcat
     9601 ggcttttgga gacaatctta atgacttaca tatgatgcag gttgtgggac atcctgtagc
     9661 tcctgaaaat gcacgaccag agattttaga attagcaaag actgtgattg gtcaccataa
     9721 ggaccagtcg gttatagctt atatggaggg cttataatgg cagatataaa attaatcgca
     9781 ttggacttgg acggtacctt gctgactact gataaaaggc tgacggatcg caccaaggca
     9841 actttgaaag ctgcgcgtga tcgtggtatc aaggtcgtat tgacaactgg tcgtccctta
     9901 aaagccatgg acttctttct ccatgagtta gggactgacg gtcaggaaga tgagtatacc
     9961 attactttta atggtggttt ggttcagaaa aatacaggtg aaatccttga taaaacagtc
    10021 ttttcatatg ctgatgtggc acgtttgtat gaagaaacag agaaattatc actgccactt
    10081 gatgccatct cagaaggaac agtttatcaa atccaatcgg accaagaaag tctttatgcc
    10141 aaattcaatc cagctttgac ttttgttcca gttgactttg aagacctgtc tagtcaaatg
    10201 acctacaaca aatgcgtgac tgcctttgct caagaaccct tggatgcagc cattcagaag
    10261 atttctccag aattgtttga ccaatatgaa atctttaaat cacgtgaaat gttgctagag
    10321 tggtcaccaa agaatgttca taaagcaaca ggtttggcaa aactaatcag ccatcttgga
    10381 atcaaccaaa gccaagttat ggcctgtggt gacgaggcca atgacctttc tatgattgaa
    10441 tgggcaggtc ttggtgttgc tatgcaaaac gctgttcctg aagtaaaggc agccgcaaat
    10501 gtagtaacgc cgatgaccaa cgatgaggaa gctgtcgcct gggctatcga agaatatgtg
    10561 ctaaaggaga actaagatat gggattgttt gaccgtctat tcggaaaaaa agaagaacct
    10621 aaaatcgaag aagttgtaaa agaagctctg gaaaatcttg atttgtctga agatgttgat
    10681 cctaccttca cagaagttga ggaagttcct caggaagaag cagaggttga aattgttgaa
    10741 caagctgtgt tccaagagga ggaaatccaa gacacagttg aagaaagtca ggattcagag
    10801 ccagctgtag gggtttctca agaagaaata gaagaattac caaactcaga agaattacca
    10861 gaggaagaga agcttgagca cgaaggaact atagaagaaa ataattctga agttcttgaa
    10921 ccagaaaggc ctcaaacaga agaaactgtt caggaaaaat atgaccgcag tctcaagaag
    10981 actcgtacgg gcttcggtgc tcgcttgaac gccttctttg ctaacttccg ctctgttgac
    11041 gaagaatttt tcgaggaact ggaagaactg ctgattatga gtgatgttgg tgtccaagtc
    11101 gcttctaact taacggagga actacgttac gaagccaagc ttgaaaatgc caagaaacct
    11161 gatgcacttc gtcgtgtcat cattgagaaa ttggttgagc tttatgaaaa ggatggtagc
    11221 tacgatgaaa gcatccactt ccaagataac ttgacagtta tgctctttgt tggtgtgaat
    11281 ggtgttggga aaacaacttc tattggaaaa ctagcccacc gctacaaacg aactggtaag
    11341 aaggtcatgc tggttgcagc agataccttc cgtgcgggtg cagtagctca gctagctgaa
    11401 tggggccgac gagtagatgt tccagtagta actggacctg aaaaagctga tccagccagc
    11461 gtggtctttg atggtatgga acgtgccgtg gctgaaggta tcgatattct catgattgat
    11521 actgctggtc gtctgcaaaa taaggataac cttatggctg agttggaaaa gattggtcgt
    11581 attatcaaac gtgttgtgcc agaagcacca catgaaacct tcttggcact tgatgcatca
    11641 acaggtcaaa atgccctagt acaggccaaa gaattttcga aaatcacacc tttaacggga
    11701 attgttttga ctaagattga tggaactgct cgaggaggtg tggttctagc cattcgtgaa
    11761 gaactcaata ttcctgtaaa attgattggt tttggtgaaa aaatcgatga tattggagag
    11821 tttaactcag aaaactttat gaaaggtctc ttggaaggct taatctaatc agaagcaaaa
    11881 atcctgcaag gtacaaactt gcaggatttt tttattcgaa acgaccatct tgacgatagg
    11941 cgatatctgg ttgccaagtc catttggcat cgaatttttc aagtaggtca aagctggctt
    12001 gaggtcccat gcttccagct ttatagtcat gaagtggggc accattttcg gcccagagct
    12061 cttcaatacg gtcaatcaac ttccatgacg caccaacctc atcccagtgg ctaaagttag
    12121 ttgagttgtt atttaggaca tcataaatca atttctcgta tggttctgga gaagcaccag
    12181 ttgcagtcgc gtctgtacga taatcaagtg agttaggagc caagttaaat tcttctccta
    12241 cttgcttccc atttaggcta agagagaagc cttctgttgg ttgaatatag atggtcaaaa
    12301 tatttggagc aagtggttct ccaaagatag aatccatttg tttaaagacg atgttgacat
    12361 gagttccttt ttcagtcagt cgtttacctg tacggaaaaa gaaaggaaca ccacggaatc
    12421 gatcgctgtc tacaaagaag gcaccagatg taaaggtttc agttgttgat tctggattca
    12481 catttggttc gctacgataa gagatgtatt tcatgccatc aatcttacca gagcggtatt
    12541 gtccacggat aaagtgttct ttgagttctt catcagttgg atgatagagg tttttaaaga
    12601 ccttaatctt ttcagcacga atctcgtctt ttgtgaagct tgctggtttg tccatggcga
    12661 ggagcgaaag aagttgtaga gtgtggtttt ggaccatgtc acggagggca ccggattggt
    12721 catagtagcc accacgttct tctacaccca agcgctccgc aaaggtaatt tgaacattgt
    12781 cgataaaatc cttgttccaa acgttttcaa aaatcaagtt tgcaaagcga actgcaaaga
    12841 tgctttggat catttcctta ccaagataat ggtcaatacg gaaaatttgt tcttcgtcaa
    12901 atgttgctag gagttcgtca ttcaacttac ttgcagttgc gtaatctgta ccaaatggtt
    12961 tttcaacgat caagcgctca aaacctttgc catcgacaat gttttcagat ttgaggtgtt
    13021 tggcaatggt tccaaagaac tgaggtgcca tagacaagaa gaagagctta ttgtgttcag
    13081 cttggtattt ttcattaagc tcagcttgta attgacgcaa agcaatataa tgttccgaat
    13141 cattgacatc atggctttga tagtagaagt ggctagcaaa ttcttgggct tgctcggtac
    13201 tatctgccaa atcaaggatg gactcgacaa ctacagattc aaaatattcc ttactccaag
    13261 gtctacgggc agttccaata acggcaaagt gcttggaaag attgccggat ttatatagtc
    13321 taaaaaggga agggtagagc ttgcgtttag ccaggtctcc actcgcaccg aaaattgtaa
    13381 caataacctt agatgacatc tagctaccta atttctattt ttattcctag tcttgctagg
    13441 tatgaggaaa cctcatttca taaacttaat tctaacataa ttttccgaaa aatcaaaaat
    13501 tccaatacga ggtagaaaaa ctgcaaggaa atccttacag tttgagttta gacgtttaag
    13561 accttatcta agaactcttt cagacgaggg tgttgtgggt tatcaaagat ttggtcaggt
    13621 gttccgtctt caaggaactc gccatctgca gtaaagataa cgcggttggc aacctgacga
    13681 gcaaatccca tctcatgggt tacgataatc atggtcatgc cttgctcagc caattccttc
    13741 ataacgttaa gtacgtctcc aaccatctca gggtcaaggg cagaagttgg ttcatcgaag
    13801 agcatgatgt ctggattcat tgctaggcca cgagcgatgg ccacacgttg tttttgacca
    13861 cctgataggc tatctggatt ggcattagct ttatctgcta gtccaacctt ttcaagcaac
    13921 tccattccca attcctcagc ttcttcctta gtcatcaact tgtgctcaat aggagcaaag
    13981 gtgatgttgt ccaatacaga catatgaggg aagaggttga agtgttggaa taccatgccg
    14041 atattttcac ggacgtggtc aacattggtt gttttttcag ttaaatcata gccgttcaca
    14101 gtgatgtgac cgctagtgac ttcttctaaa agattgaggc tacggaggaa agttgactta
    14161 ccagaacctg aaggaccgat gatacaaaca acatctcctt catagaactt agtcgtaatt
    14221 ccttttagga cttcattttt tccatagtgc ttgtgtaaat catttacatc aatttttaat
    14281 tttgccatta acgaatcctc ttttctaagc gtttcgctag tctagtcaaa agtgtgataa
    14341 ttacaagata gaagatagca aggattgcat acatcttgaa actttggtag ttacgagcaa
    14401 tgataatctt accagtttgg aagagttcaa ccaaaccgat agcagatacg atagttgtat
    14461 ctttaagagc gataacgaat tggttgacaa agtttggcaa catcaattta gttgcttgtg
    14521 gcaagataat cttacgcatg gtttttccat aagagatacc caagcttcgg ctggcttcca
    14581 tttggccaac tggaacggcc tgaataccac cacgaacgat ttcagcgata taagcagccg
    14641 cattgagtga gagggcaatt gttccagcta caaagtcgtt aattgggctt tgttggcctg
    14701 tgatagactc gatgaagttt ggaattcccc agaagatgaa ggctgcaaga atcatcaatg
    14761 gaataccacg aataacgtca acgaaaatct cagagatgac gcgaagagat ttgtatgggc
    14821 taacgctaaa cataccgaag ataattccga tgacaatggc aatagcaaat gagataagag
    14881 ctagagcaag agtgatacca agaccgctaa ggagttgttt gtagttgttt tgaagcaagc
    14941 cccagagcgt tgtttcgtca acagtacttg ttgaagcagt tgaagattcg ctagctaggt
    15001 atttgtcaag aatcttttgg aattcaccgt ttgctttaag gtttgcaagt ccgttgttga
    15061 acatttcaat cagttctgga tttgctcctt ttttaacggc aaaggctgtt tcaccgattg
    15121 gagttccaga gattggagtt ttcaattttt gactttggct gatagaatat ttgagaacag
    15181 gttcatcatc cataacggca tcaatggcac cagtgtttaa actgtcatac attgaagaac
    15241 catcagcaaa ggttttgatt ttgtaaccgt atttgctttg attttctgtt aggaaggttt
    15301 gagaagcagt tccgttttta acaccgactg tctttccttt tagatcttca taagaagcaa
    15361 tattgcttga ttctttgaca ccaagaatgg tattagcagt gtagtatgat tctgagaagt
    15421 caaaagttgc cttacgagca tctgtgacag acataccagc aatgatacca tcggcttgac
    15481 cagcttggac agcactgata gcagcatcaa aaccagggtt ggtgatttca atttcaaaac
    15541 cttggtcttt agcgattgcc ttaatcaatt ccatatcaat accagtgtat tggttgcttg
    15601 aattttggaa aacaaaaggt gcaaaagaag aatcgctggc aatgatatat ttagccttaa
    15661 caggaatagc ttttaatcct gcgagagtag ttgtagttgg cactgctgaa gatgatgaag
    15721 cagtccattt cttgataatt ttatcaagac taccatcttt tttcatttca gacaaggctt
    15781 ggttaaattc agtaaccagg tgctcgtatt tacttccttt tttcacaccg aaagcaaaac
    15841 ttcctacagc ttcaccatcc atttcaatat ggaggtcttg accttggtta atggcatatt
    15901 cgataacagg tttgtcatcc atcatggcat cgatggcacc agcactcaag ctgttgttca
    15961 ttaaatcacc agtgtcaaat gttttaatag taaagccgta tttatctttg attgtttcaa
    16021 ggaaacgttg agcggcagtt ccgtttttaa caccaacggt tttgccagtt aattggtcgt
    16081 acttgctaat tttgtgtgac tttgtagtag caatgacaac ttttgtatca tagtaagtat
    16141 cagacatggt gaagactttt tcacgttctt tagtctttgt catccctgcc atgatagcgt
    16201 cggcttgccc agcttgaacc gcattgactg ctgcgtcaaa tccaggatag gacatctgaa
    16261 tgttccagcc tttaatctca gcgactttgt taataatgtc aacatcaatt cctttataag
    16321 tttgatctga atctttaaac tcaaaaggtg cataggcggt atcagaaaca atcttaatcg
    16381 tttctgcttt ggcaatacct aatgagaaaa ttgggaataa aattagcaaa aatgctagaa
    16441 attttttctt catttttagt ctccttttcc gaatattctc tcattatatc agaaaaagta
    16501 aaaaaaggca aatttttata tttttcgtgt cagaaaatat aacattgatt ttttcctttc
    16561 cttgaattgc tattaaaaag tgctataata atagtatata tagaagaaaa gaggacgggg
    16621 atatgaagaa caaaagaata tttaaagact tccaagcttc aaaaatgagt ttaaacattt
    16681 acacaagccc cttgttagcc tttgtttttg tcttcatagg agagtttgtg gcttttactt
    16741 tgtatggtat tggcttgtta gctctcatcg gacttgctag aaattttgga gaggctggtc
    16801 aaaatcttgc aagctacttg cagaccttgc atcagagctt gacggataaa acaagtgact
    16861 ttcgtttaat tttaggatta ctggcctttg gttttattct taacactgtg ttcagatgga
    16921 caagaaaagt tgagaaaaga cctattcgaa ccttgggatt ttatagagag aatttcctca
    16981 gcaatcttct gaaaggattt agtctaggtc tggcactttt tcttctgacc ttgttaggtt
    17041 tggtggtctt aggtcaatat cgtttggaat tcattcactt gaatccttat tctcttgcct
    17101 ttgtcgtctt tactatccca ttttggattt tacaggggac agcagaagaa gtggtggccc
    17161 gtgcttggct acttcctcaa ttggcctcaa gaaccaatct aaaactagct attcttatat
    17221 ctagcctgtt ctttaccctg cttcatatgg gcaattctgg cctcacccct ctatctctag
    17281 taaatctctt tttattcgga gttgccatgg ctctttacct tctcaaaact gatacagttt
    17341 ggggtgttgc aggtattcat ggtgcttgga attttgctca gggtaatctc tttgggattt
    17401 tagttagtgg tcaaccgtca ggaacgtctc tgatgacctt tttaccacaa ggcaatcaag
    17461 attggctatc aggtggttct tttggcatag aaggttccat tatgacaagt ctggtattac
    17521 tactgctgat tgtctatctt gctaataaat taaagaaaga aaatgaaagg atgtgacttc
    17581 ggtccatcct tttcttcgtg aaaatactat aagtatgcta aaataggaat agcacatgga
    17641 gagaggattc ttatgatcaa tcacattaca gataatcaat ttaaactagt atcaaaatat
    17701 caaccatcag gagatcaacc ccaagctatc gagcagttgg tggataacat tgagggggga
    17761 gaaaaagcac agattctgat gggggcgact ggaacaggga agacctatac tatgagtcag
    17821 gtcatttcta aagtcaataa accaactctg gttattgccc acaataaaac tctggctggt
    17881 cagctctatg gggagtttaa ggaatttttc cctgaaaatg cagttgagta tttcgtatcc
    17941 tactatgatt attaccagcc agaggcctat gtcccttcta gcgataccta tattgagaag
    18001 gatagttctg tcaatgacga gattgacaag cttcgccact cagctacctc agcccttttg
    18061 gagcgtaatg atgttattgt cgtggcctca gtctcttgta tctatggttt gggttcgccc
    18121 aaggaatacg ctgatagtgt cgttagtctc cgtcctggtc tagagatttc tcgtgataaa
    18181 ctcttgaatg acttggtcga tattcagttt gaacgcaatg atattgattt ccaacgcgga
    18241 agatttcgcg ttcgtgggga tgtggtagag attttcccag cttcccgaga tgaacatgcc
    18301 tttcgagtag aattttttgg agacgaaatt gaccgtattc gtgaagttga ggctctgaca
    18361 ggtcaggtgt tgggagaagt ggatcattta gcgattttcc cagcgacaca ctttgtgacc
    18421 aatgacgacc acatggaagt tgccattgca aagattcagg ccgagttgga agaacaatta
    18481 gctgtctttg aaaaggaagg taaactgctt gaagcccagc gtttgaaaca gcggacagag
    18541 tatgatatcg aaatgttgcg tgagatgggc tataccaacg gggttgagaa ctattcacga
    18601 cacatggatg gacggagcga aggagagcct ccttatacgc tcttagattt cttcccagat
    18661 gattttttaa ttatgattga cgagagtcac atgaccatgg ggcaaatcaa gggcatgtac
    18721 aatggagacc gttcgcgtaa agaaatgctg gttaattatg gtttccgttt gccgtctgct
    18781 ttggacaatc gtcctctccg tcgggaggag tttgagagtc acgttcatca gattgtttac
    18841 gtttcagcga cacctggtga ctatgaaaat gaacagaccg agacagtgat tgagcaaatc
    18901 attcgtccaa cgggactctt ggatccagag gtggaagtcc gtccgactat gggacagatt
    18961 gatgacctct tgggtgaaat caatgcccgc gttgaaaaaa atgagcgtac ctttatcaca
    19021 actttgacca agaaaatggc agaggacttg accgactact tcaaggaaat gggtatcaag
    19081 gtcaagtaca tgcactcgga tatcaagacc ttggaacgga cggagattat ccgtgacctg
    19141 cgcttgggtg tctttgatgt cttggtcgga attaacctgc tccgtgaagg aattgacgtt
    19201 cctgaagtga gcctcgtagc tattctcgat gctgacaagg aaggtttcct acgtaacgag
    19261 cgtggactca ttcagactat tggtcgtgct gcccgtaaca gtgaaggtca tgtcatcatg
    19321 tatgctgaca cggttaccca gtctatgcaa cgtgctatcg atgaaactgc ccgccgtcgg
    19381 aaaatccaga tggcctataa tgaagaacat ggtatcgttc cacaaaccat taagaaagaa
    19441 atccgtgacc tgattgccgt aactaaggca gttgctaagg aagaagacaa ggaagttgat
    19501 gttaatagcc tcaacaaaca agaacgtaaa gatcttgtta agaaactcga aaaacaaatg
    19561 caagaagccg tcgaagtgct tgactttgaa ctagcagcac agattcgtga tatgatgttg
    19621 gaagtcaagg cgttagatta gaataatatc taaaggagaa aatatgtccc gttcccaatt
    19681 aacgatttta acaaacattt gtctgattga agacctcgaa actcagcgcg tggtgatgca
    19741 gtatcgcgcc cctgaaaaca atcgctggtc tggttatgcc tttccaggag gccatgtaga
    19801 aaatggcgaa tctttcgtag agtctgtcat tcgtgaaatc tatgaagaga caggattgac
    19861 tatccaaaat ccacaactgg taggcgttaa aaattggcct ctggatacag gcgggcgcta
    19921 cattgtcttt tgttataggg cgaccgagtt ttctggaact cttcaatctt cagaagaggg
    19981 agaagtttct tgggtgcaaa aagaccagat tccaaacttg gatctggcct atgatatgtt
    20041 acccttgatg gagatgatgg aagctcctga caaatcagag tttttctacc ctcgccgtac
    20101 agaagatgat tgggagaaga aaatcttcta gtcttttact aaataaccta gctgatccaa
    20161 gacctcctca atatagtgga ggtcttgttg tgtttcgtat ctaatagtat agtagattga
    20221 aataagatat aaacaaatca atcaggaaag taaaattaat ttctagaaat attttagcag
    20281 tcacgacgta ctattctggt ttcaatcaat tataatagaa gattagtaaa aacatgtgta
    20341 ctctgaaata aatttaaaat atttctaaaa aagtattgac aaaataaaag aaaacgctta
    20401 ctatataaat aagggaacgg ttccacaata aaaaaggagg agtgatgact acaataaaac
    20461 aggttgctga agaagctgga gtatcaaagt caacagtttc aagatatatt tcgaaaaaag
    20521 gctatgtcgg agatgatgcg agagaaaaga taaaaaatgc tatcaagaaa ttaaattaca
    20581 caccaaatgt attagcacaa tctttaaaaa ctaaaaaaat caaatggtag gactcttatt
    20641 gccagatatt tctaatccct tcttcccaag attggttcga ggagccgaat catatttgaa
    20701 agataaaggt tataggatta tggttggtac tatttcagat catgattcgt tagaagaata
    20761 tataaacctt ttgttaaaaa caaatgcagc tggtattata acaacacttg actttacaaa
    20821 ggaatttcca aatctaacat tacctgttgt tgtggttgac cggattagta aagatacagg
    20881 ctatggtgtt ttttctgata atcagttggg tggacgtttg gctgctaaag caatttggaa
    20941 tgctggcgct gagcaggtta tgatcatcaa agttttagat gataaagctg agaatattgt
    21001 ggaacgattt gaagcaagtt taaactactt gaggaataaa aatttagaaa tttgtattga
    21061 agaaagtgaa acgtttgact ttgaaaaaat tcaaaaagaa gctaaagaga atctaaaaag
    21121 aaatccaaat attgatagta ttatagcacc ttctgatatt catgcgatag cttatattca
    21181 tgaaatttta gcaattggga aaaaaattcc agatgatatt caaatcattg gttatgatga
    21241 tattgtactt agtcaattta tttatccttc tttatcaact atccaccaat catcatataa
    21301 aatgggagaa caggctgcaa agctaatcta taatatggca aataagttct ctatagatga
    21361 agctaaaatt aaactccctg ttaggtacat agaaagaaat acattaagga gaaagaaatg
    21421 agtaaaattg ttgttgttgg aagcatttca atggacttag ttatgagaac aaaaaggatt
    21481 ccagaaggag gtgaaacgat ttttggcgat tcatttaata tagttccagg tggaaaaggt
    21541 gcaaatcaag ctgtagctat tggtagatta tccagtgttg aagataatat ttacatattt
    21601 gggaacgtag gagaagatat tttttcagca gatttattaa gtaatctgca aaataatgat
    21661 atttctacag catatgtggg aacggtacca cagtctacag gagttgcaca aattacttta
    21721 tatggaggtg ataataggat tatttattat cccggagcta ataatttagt taaaacaaat
    21781 gattggaaaa atgagtggaa attacttagt gatgcaagta ttgttgtatt acagaatgaa
    21841 ataccacatg aagccaactt atctatagct aaattttgcc aagaaaatca agttaaggtt
    21901 ctttacaatc ctgcaccagc tagagaaaca gacaaagaga tgattccttt ttgtgatttt
    21961 attactccta atgagcatga atgttcagag ctttttccag ataagaaatt agaggaaatt
    22021 attaaaattt atcctaataa aatgattgta acattaggag ttgaaggctc tatttattat
    22081 gatgggacag cagttaagaa aattcctgct ataaaagctg aagtagttga tactacagga
    22141 gcaggagata cgtttaatgg tgcttttgct tatgctatct caaaaggaaa agagatgaat
    22201 gttgcattgt cctttgcaac gattgcttca catctttctg ttcaaagatt tggagcacaa
    22261 ggaggtatgc ctagtttgaa agaaataaag gagcattcag gatatgaaga aatatgggat
    22321 tttaaatagt aatatagcaa aactagctga tgatttaggt catatggatt gggtttgtat
    22381 cggagatttg ggattgccag tcccaaaagg tgttgataaa attgatttag cattaagaaa
    22441 aggtagtcca agttttttag aagttttaaa agaatattca gatcatgtac ttattgaaaa
    22501 aattttctta gcagaagaaa ttaaagaaca aaacacagaa cagtggcaag cagttttaga
    22561 ccttttagga tcgaatataa ttattgaata tattagtcac gaagaattga aagctatgaa
    22621 tactaaagta aaggcagtta ttcgcactgg ggaagataca ccatattcga atataatctt
    22681 gcaatcagga gttattattt agaagggggt tacctatgaa aattgaaatg aagaacattt
    22741 caaaatcttt tgggaataat cgtgttttag aaagtattga tttggttctt aattcaggag
    22801 aagttcatgc tttaatggga gaaaatggtg caggcaagtc aaccttaatg aatattttaa
    22861 ctggtctttt tccagctact tcaggaacta tttttattga tggaaaagaa aaaacatttt
    22921 ctaatcctca agaagcagaa cggtttggac tgagttttat tcatcaagaa atgaatactt
    22981 ggccagatat gactgtactt gataatcttt ttttaggaag agaaattaaa aattcgattg
    23041 gctttctaga taaagctagt atggaaaaga aagctaaaga agcatttaaa cgtcttaata
    23101 tctctattcc tctcgatgca attattggtc aattatcagt tggacaacaa caaatgatag
    23161 aaatagcaaa atgtttatta tcagaagttt ccttgttaat tatggatgaa cctacagcag
    23221 ctttaactga tcgtgaaact gaaacacttt tcaaagtgat agaaggatta aaatctgatg
    23281 gtgtaggtat tgtgtatatt tcacatcgca tggaagaaat ctttaagatc acagatctta
    23341 taactgtaat gagagatggg tttgtaattg ataccaagaa aacgaagtta actaatgcgg
    23401 atgaattagt tcaaaagatg gtaggtcgtg aattagaaga ttattatcca gaaaaaaagg
    23461 ctgagattgg gaatattgtt tttcaagcta agaatctttc tggtaattct tttacggatg
    23521 tttctttcta tgtacgtcaa ggggaaattc ttggtttttc tggtttgatg ggggctggtc
    23581 gtactgaaat aatgcgagca atttttggaa ttgattcttt aaaatctggt caaattataa
    23641 taaacgaaga agaactgata attaaaaatc cttttgaagc aattaagcat ggaattggtt
    23701 tcttaacaga agatcgtaaa gatgagggat tgattttaga tttttctatc aaagataata
    23761 tgactttacc tagtactcgt gattttgtta aaaatggcat ttttgataat aaaacaagtg
    23821 atatatttgt acaacgctta attgataggt tacaaattaa atcaggttat ccagataaag
    23881 aagttgggac actttctggt ggtaatcaac agaaagtagt tttagcaaaa tggataggta
    23941 ttgcaccaaa agtactgatt ttagatgagc caactcgtgg ggtagatgtt ggagctaagc
    24001 gtgaaattta ccaattaatg aatgaattgg ctgaacgagg tgtaccgatt attatggtct
    24061 cttcagattt accagaagtg attggagtca gtgatcgtat tatggtcatg catgaaggta
    24121 gaattagtgg agaattaaca cgtcaagaag ctacacaaga aaaagttatg caactagcta
    24181 caggaggaca atagtgtgaa aaatactatg aagtatatgt cagaattgac aacagtaata
    24241 gcattgataa ttttaatggc tgtcatcact attatcaatt caaatttttt aacagcaaat
    24301 aatctgttaa atttactatt gcaagtaaca tcaaatgcac tgattgcttt tggaatgacc
    24361 tttgttattc taacaggtgg aattgattta tcagttggat caattttagc cttatccagt
    24421 gcgctaacag ctggcctatt aggatctgga atgcctgtta cattagcaat tctcatctct
    24481 ttaattttgg gttgcattct aggtatgatg aatggattat tgatttccta cgggaaatta
    24541 gctccattta tcgtcacttt agcgactatg actattttta ggggagcaac acttgtttat
    24601 acaaatggaa atcctattac aaaaggatta agtgatacat tcttatttca atttttgggg
    24661 caaggttaca tagtaggaat tccatttcct gtaattatta tgtttattgt atttattgtt
    24721 ttatatgttt tacttcataa aacagcattt ggtaaatctg tatatgctat aggggggaat
    24781 gaaaaagcag catatatatc aggtgtaaaa ttaaataaag tgaaaattat catttattca
    24841 atatcaggta ttatggcttc aatttctgga ttgattataa catcacgctt aagttctgct
    24901 caaccaacag caggtgctag ttatgaaatg gatgctattg cagctgttgt tcttggggga
    24961 acctctttat ctggaggtaa aggtcgtata ttggggactc taataggtgc tttaattatt
    25021 ggagttttga ataatggact taatattatt ggtgtttcag cattttggca acaagtagta
    25081 aaaggagttg taatcttaat tgctgttttg attgatcgtt ttaaagttgt aaaatagtag
    25141 aataattttt caagtttttt ggaaatagta acaatttatt agatgacgaa caatagtcgg
    25201 gatggaaact atccctgtag atatatatta cgaggagtaa taacatgaaa attattaaaa
    25261 aaattagcat ttttgctttg tttgtaacat ttatttttgc tttagtagct tgtggaaaaa
    25321 ctggtttagg aaattcatca aatgataata aatctacgac acaaaagtcg gcaaaagaat
    25381 taaaattagg agtttctatt tctactacta acaatcctta ttttgtggct atgaaagatg
    25441 gtcttgaaaa agctgcaggg gaaaaagaag taactttgaa gatagcagat gcacaagatg
    25501 atgctgctag acaagcagat gatattcaaa attttattag tcaaaatgta gatgctttgc
    25561 taattaatcc agttgattct gatgcaattg tgacatctat taaagctgct aataatgcaa
    25621 acattccagt aatcttaatt gaccgcggta gtaatggtgg tgaagtcttg acaactgttg
    25681 cttctgataa tgtagaagcg ggtaaaatgg ctgctgaatt tattaccaag caattgggag
    25741 aaaaagcaaa aacttttgaa ttatcagggg tcccaggcgc ttctgcaaca gtagatagag
    25801 gtaaaggatt tgaacaaatt tcaaagacaa atttagatgt tctttctagt caatctgcta
    25861 attttgatcg tgcaaaagct ttgaatacag cgcaaaatat gattcaagga aacaaagaag
    25921 tacaagcgat tttcgcacag aatgatgaga tggcattggg agctgcacaa gcagtaaaag
    25981 cagctggtct tagcaatgta ttaattgttg gtatcgatgg tcaaccagat gcacatgatg
    26041 ctattgcaaa aggtgatatt actgccacta ttgctcagca accagctaag atgggtgaaa
    26101 tcgccattca atcagcaatt gatcattatc aaggaaaaaa actagaaaaa gaaacagttt
    26161 ctccaattta tcttgtgact aaggataatg ttgatcaaca taactggtga tatattttta
    26221 ataagtagat acttattcat cttcattcaa tgtagttttt aaatatcatt gctactattt
    26281 gaactcttgg gtgcaaaaag accagattcc aaacttggat ctggcctatg atatgttacc
    26341 cttgatggat atgatggaag ctcctgacaa atctgaattt ttctaccctc gccgtacaga
    26401 agatgattgg gaaaagaaaa ttttctaatc ctttactaaa taacctagct gatccaaggc
    26461 ctcctcgata tagtggaggt cttgttgtgt ttcggcttcg actaggtggt aatggatgcc
    26521 atctgttaat tcagacagag gtctaaaatc tgaatgctcg acttgttcta gaaaatgttg
    26581 cacatctcta cgacaagaca gtttcagcaa ggtttcaatt tctccataga caggatggtc
    26641 aatcaaagtg ttttgaacac gtccaccatt atctacgata gtaaggagtt cctgaccgat
    26701 ttcttcaact tcatgtttca ctttgaatag tttgtgaaca taaggattgg tatcaatttg
    26761 cttatagatg tagccacgat tagtggatag gataggagcg ccatcggctc ttaaaattgc
    26821 aatgtcttgt acaatgacct gacgtgtgac atgaaaatgt tcagctaaac tttggccatt
    26881 aagggcttta ggagcttctt tcaagagttg gagcagggct tgtttgcgat cttttgtcat
    26941 agttcttcct tttaacggcg ttttcgaagc actttataga cagctagtgc taatgtatag
    27001 tctaccatac tatggataat tgtgccaaat ccaactagca caaagagaac ataaaacata
    27061 ttttctacat tggtaccaga agttgcgtaa aaaacgacac aggctaatac ttcagcaagt
    27121 gcatgaacaa cagccaaaac aaagttgaaa acccaggaag attttggttt atctagggta
    27181 tcggggaatt ttcgtaggta aagagctcct agggtaccaa aaacgatatg agagaaagct
    27241 ctaaaaacaa taaccatggg atagccagcc atcaaaaatc caaaactaga agctaggatg
    27301 acaaaaactg ccatcaaggg cgacaagaac atggctataa aaatagcgat gtggctcccc
    27361 aaagtatagg aagcaggtgg aatgacaatc ttgaaaggca taacaattgg aatcaaaatc
    27421 gcaatagccg ttaaaagggc tgtcattgtc ataaattgtg tctttttccg tgtattcaca
    27481 agaatctcct ttttaactgc atatacacta gtatggtaca ataaaccaga caataaagca
    27541 agaatttact tgggtttata gatcattttt tagttaaaag ttatagtgga ttgaaactag
    27601 aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt
    27661 tgtcctgttc ttatttcgtt ttactatagt aaagatttca ttaaaaagaa actgtataga
    27721 gcaaaatctc caccttcagg tttgaaagcg gagattgttt ttattttttc aaggtttgta
    27781 gtcgtggaac aatggctagg gttagaattg cagaaatgac caattcagca attgaatttg
    27841 ttgagataac ggttgccaga agaagttgga tatttccatt ataaacattt ccaaatagga
    27901 agaagattcc tccaaggaca aagatagtat ttgtcaagga accaagggcc ccagctaaaa
    27961 tcagaccagt cttgtttttc atcagtttat agactaagta aggagttaaa ccaatcaaaa
    28021 tacgtgggac aatggcaatg atagctgagt agatgtttcc gtttggtacg aagggagaga
    28081 agaggtagct tgtcggtaga atcgtaatcg tgttaaccgt caagctaagt aatcccatca
    28141 aaaatccaag tgtaacccca actcgtggac cataaataat gctggcaata atgacaggaa
    28201 tatgaacaat ggtcggtttg attggaaatg gaaaaaggtt aaagataagt gagctcagaa
    28261 agtgtatcac gagcatggta gcaaaaaaga tagcaatggg tgcaatatta gagcgttttt
    28321 tcatcgatag tttcctttat tctttctaaa ataattgtga ggtcagctaa agctcctcgt
    28381 ccgtggtctc cacaagctag tagggattcc ttaggagcaa tcagctgata gccgtaggtt
    28441 tctaatgttt tcagattatt ctgagttact ggatggtcat acatttttgt attcatagca
    28501 ggagctatta gtttgggaat atgacttggt agggctagag ctgtactggt taccatgttg
    28561 tccgcaaagc cgtgagctag ttttgcaata gtgttagcag ttgcaggtac cacgataaat
    28621 aaatctgctt tttttccaag ttcgatatga ttgacctgat caggataggg ttccttcatg
    28681 acatccaagt ggacaggatt ctgtgagagt acctgtagtg acaaaggttg gataaactct
    28741 gtagcagcct gagtcattaa gacagtgact tgatggcctt gtttttttag agaactgact
    28801 aaatctgccg acttataaga ggcgattgaa cccgttacag ccaagagaat gtttgccata
    28861 gttttccttt ctaagaatga taggcttgaa ttttttcaag gaggagttct gcaatttctt
    28921 ctttagtctg gactgtttga agctgatttt tctcaacaaa tatagctcgg tgctgatctg
    28981 ctgaaatttg agtcaggtca ttcgcgatga ttaaatctgc ttgattcttg ataagacttt
    29041 ttcgtgcaat atcaaccaga tgatcttcgg taacatcaac cagcagtttg aaaccaatca
    29101 gatgaatagt agaattccat tccttgacta gggatatgat tttgggtgtc tttttaagga
    29161 acaaaacctg aacctcatca gttgaagaaa tcttggcctg atgattctgc ttgcttaaaa
    29221 attcttttag attggagcta gcctgaactt cctcaagccc tgtcatataa acaggagtgt
    29281 agtcagaaac agccattgag tggatcaaga tctgataatc ctgaacacgt tcttgcattt
    29341 ctattagaag gtccttggta ttggtaattt ctcgaatact taggttagga tgagactctg
    29401 gcttcagagc tcgttttgtc gtaattaaac aaacttcatg ccctgcagaa agcaaagtct
    29461 ctgtgataat tttccccaag tgacctgtag aatggttagt gatagagcgg acgctatcga
    29521 tagcttcact ggtaccgccc gatgtaacta aaattttcat agcactattg tacacaaaaa
    29581 taagcggtaa gtaaaatgaa agtgataaat ttttggtaaa aacgaagatt tattatagtt
    29641 tcaaactata aagccatata aaatttaaga aaggactcta aaagtcttaa aaacagagat
    29701 atttacgaac gtttagagag ttttaggatg ttaaaaatct tgttttgtga tataatgaat
    29761 tatcatataa gaggttagag gaattttgaa tgaaaacaga tattgaaatc gcacagagta
    29821 ttgagttgaa gccaattgtt gatgttgtag agaaacttgg tatttcttac gacgatttgg
    29881 agttgtacgg aaagtacaag gctaaactca gctttgataa aattcgggca gttgagagca
    29941 atccagtcgg taaattgatc ttggttactg ccatcaaccc aacacctgca ggtgaaggaa
    30001 agtcgacgct taccattggt cttgcggatg ccttgaacaa gattggcaag aaaaccatga
    30061 ttgctatccg cgaaccgtct cttggtccag tcatggggat caagggtggt gctgctggtg
    30121 gtgggtatgc acaagttctg ccaatggaag acatcaacct ccactttact ggagatatgc
    30181 atgctattac aactgccaac aatgcccttt ctgccttgat tgacaaccac ttgcaccaag
    30241 ggaatgagct gggaattgat caacgtcgta tcctctggaa acgcgttgtg gacttgaacg
    30301 accgtgcgct ccgccatgtg actgttggtc ttggtggtcc tctaaacggt attccacgtg
    30361 aggacggttt tgatattaca gttgcttcag aaatcatggc aattctttgc ttggcaacgg
    30421 acatcgagga cttgaaactt cgtttggcga atatcgttat tggttatcgc tatgaccgta
    30481 cgcctgtttc tgtaggtgat ttgcaggttg agggtgcctt ggctttgatt ttgaaggatg
    30541 ctattaagcc aaacttggtt cagacaattt acggtacacc tgcctttgta cacggtggtc
    30601 catttgccaa tatcgctcat ggctgtaact ctgttttggc gacgacaaca gcccttcact
    30661 tggctgatta cactgttact gaagctggtt ttggtgcgga ccttggtgct gagaaattcc
    30721 ttgatatcaa gacaccaaac ttgccaacat ctccagatgc agttgttatt gtcgcaaccc
    30781 ttcgtgccct taagatgaat ggtggtgtgg ctaaagacgc tctgactgaa gaaaatgtag
    30841 aggcagttcg tgcaggtttt gctaacttga aacgccacgt tgaaaatatc cgtaagttcg
    30901 gtattccagc agttgtagct attaacgaat ttgtatctga tacagaagct gaaattgcag
    30961 ccttaaaaga actctgtgcc tcaatcgatg taccagttga attggctagt gtctgggctg
    31021 atggagcaga aggtggagta gcacttgccg aaacagttgt taagacaatt gctgaaaatc
    31081 cagctaacta taaacgtttg tacgataatg acctttctgt ccaagaaaag attgaaaaaa
    31141 ttgtcactga aatctatcgt ggtagcaaag tgaactttga gaagaaagct caaacacaaa
    31201 ttgctcaaat cgttcaaaac ggttgggaca aattgccaat ttgtatggct aaaactcaat
    31261 acagtttctc agacaatcca aatgcgcttg gagcaccaga aaactttgaa attaccattc
    31321 gtgaattggt accaaaatta ggtgcaggct tcatcgttgc cttaactggt gatgttatga
    31381 ccatgccagg tcttccaaaa cgtccagcag ctctcaacat ggatgttgaa agcgatggaa
    31441 ctgtactagg cttgttctag tggattgaaa ttgactttaa gtgagtttgg aaataatatc
    31501 caagctcatt ttttctcaga ctgcaagcag ttcatcaata agatttatac tcttcgaaaa
    31561 tcttttcaaa ctacgtcagc ttcaccttgc cgtaggtata tgatactgac tctgtcagtt
    31621 ctatccacaa cctcaaaaca gtgttttgag caacctgcgg ctagtttcct agtttgctct
    31681 ttgattttca ttgagtataa gtagatagaa aagttatata ctatctattg aaaatattat
    31741 aaatcagata caaagacagg tgaaaccttc tgtgttatac tagagatatg ttagatttga
    31801 aagaatacgg tatcgtcatg tggccggagg agaaagtcat ttctttccgt gagaaacttc
    31861 tcgcttggta tgatgaaaac aaaagagatt tgccttggag gagaagtaaa aatccttatc
    31921 acatctgggt atctgaaatc atgcttcagc agaccagggt ggatacagtt atcccttact
    31981 acgaaagatt cctggactgg tttccaactg tcgaaagtct ggcaactgcg tctgaggaga
    32041 gtttactgaa agcttgggag ggcttgggct attattctcg agttcgcaat atgcaggctg
    32101 cagcccagca gattatgact gactttggtg gccaatttcc aaatacctat gaaggaattt
    32161 ccagcttgaa agggattgga ccttacacag caggagccat ttccagtatt gcttttaact
    32221 tgcctgagcc agctgtagat ggtaatatca tgcgggtctt ggcgcgtctg tttgaagtca
    32281 accacgatat tgggattcca agtaatcgaa aaatttttca ggcaatgatg gagatcttga
    32341 ttaatccgga tcgtccgggt gattttaatc aagccttgat ggacttaggg tctgatattg
    32401 agtctcctgt aaatcccaga cctgaagaaa gcccagtcaa ggactttagt gcggcatatc
    32461 agaatggaac catggaccgt tatccaatta aatctcctaa gaaaaagccg gttcctattt
    32521 atcttaaagc cttagttgtg aaaaattctc aaggacaatt tttacttgaa aaaaatgaaa
    32581 gcgaaaagct cttggcaggt ttttggcatt tcccctttat agaagttgat aacttttcgc
    32641 aagaagagca gtttgacctc tttcatcagg ttgcggaaga aagtgtgaac tttggcccca
    32701 gtccagaaga gagtttccag caggactatg acctagatgt tgattggctt gatgtttgtt
    32761 ttgatacagt ccagcatgtt tttagtcatc gaaaatggca tgtacagatt gtagcaggtc
    32821 aggtgagtga cttccatgat ttttcagata gggaagttcg ttggctttca ccagaagaat
    32881 tcaagaatta cccacttgcc aaaccccaac aaaaaatctg gcaggcttat gcacaagcca
    32941 acttagacag tagccaagac tagctattgt gtcttctgac tattttttgg tataatagta
    33001 gagaaaaagg tgaacatatg aaaaaaatac taattgtaga tgatgagaaa ccaatctcgg
    33061 atattatcag gtttaatatg accaaggaag gttacgaagt tgtaactgct tttaatggtc
    33121 gtgaagcgct agagcaattt gaagcagagc aaccagatat tattattctg gatttgatgc
    33181 ttccagaaat tgatggttta gaagttgcta agaccattcg taagacaagc agtgtgccca
    33241 ttcttatgct ttcagccaaa gatagtgaat ttgataaggt tatcggtttg gaacttgggg
    33301 cagatgacta tgtaacgaaa cccttctcca atcgtgagtt gcaggcgcgt gttaaagctc
    33361 ttctgcgtcg ttctcaacct atgccagtag atggtcagga agcagatagt aaacctcaac
    33421 ctatccaaat tggggattta gaaattgttc cagacgccta cgtggctaaa aaatatggcg
    33481 aagaactaga cttaacccat cgtgaatttg agcttttgta tcatttagca tcgcatacag
    33541 gtcaagtcat cacgcgcgaa cacttgcttg agactgtctg gggttatgac tattttggtg
    33601 atgtccgtac agttgatgtg actgtacgac gtctgcgtga gaagattgaa gatacgccca
    33661 gccgaccaga gtatatcttg acgcgccgtg gtgtagggta ttacatgaga aataatgctt
    33721 gatttactga aacaaaccat ttttaccaga gattttatct ttatcctgat tttgttaggt
    33781 ttcatccttg ttgtgaccct cttattactg gaaaatagac gtgataatat tcagttgaag
    33841 caaatcaatc aaaaggttaa agatttgatt gcaggagatt attccaaggt tcttgatatg
    33901 caaggtgggt ctgaaatcac caatattacc aataatttga atgacttgtc ggaggttatt
    33961 cgtctcactc aggaaaatct agaacaagag agtaagaggc taaatagtat tctgttttat
    34021 atgacagatg gggttcttgc gaccaaccgt cggggtcaga ttatcatgat taatgataca
    34081 gccaagaagc aactggggtt ggttaaggaa gatgttctga atagaagcat tttggaattg
    34141 ctcaagatag aagaaaacta tgaattgcgt gatttgatta cccaaagtcc agaattgttg
    34201 ctagattccc aagatatcaa tggcgaatat ttgaaccttc gagttcgctt tgccttgata
    34261 cgtcgagagt ctggctttat ttcaggtttg gtggctgttt tgcatgatac gacggagcag
    34321 gagaaggaag aacgagaacg aagactcttt gtttccaatg ttagccatga gttacggact
    34381 cctctgacta gcgtaaaatc ctatcttgaa gccttggatg agggggcttt gtgtgaaact
    34441 gtagcaccag actttatcaa ggtttctctt gatgagacca accgtatgat gcgcatggtg
    34501 acggatctcc tccatctttc acgtattgat aatgctacca gtctcctaga tgtggaactg
    34561 attaacttca ctgcttttat tacctttatc ctcaatcgtt ttgacaagat gaaaggacag
    34621 gaaaaggaga aaaaatatga gttggtgaga gattatccca tcaattctat ctggatggaa
    34681 attgatacag ataagatgac gcaggttgtc gacaatattt taaataatgc tattaagtat
    34741 tcgccagatg ggggtaaaat cactgtcaga atgaagacaa ctgaagacca gatgatttta
    34801 tccatttctg accacggttt ggggattcct aagcaggatt taccacgtat ctttgaccgt
    34861 ttctatcgtg tggatcgtgc tagaagtcgt gcacaaggtg gtacaggtct aggactgtct
    34921 atcgctaaag aaattatcaa acaacataag ggctttattt gggccaagag tgaatacggc
    34981 aagggttcaa cctttaccat tgtgctccct tatgataagg atgcagtgaa agaagaagta
    35041 tgggaggatg aagtagaaga ctagaatgag tgaaataggc tttaaataca gtattttagc
    35101 gtcgggttcc agtggaaatt ctttttatct ggaaacctca aaaaagaagc ttttagtgga
    35161 tgcaggcttg tctggcaaga aaattaccag tctgctagct gaaattaacc gcaagccaga
    35221 agacctggat gccatcttga ttacccatga gcattcagat catatccatg gagtaggcgt
    35281 tttggctcgc aagtatggta tggatcttta tgccaatgaa aagacctggc aagctatgga
    35341 aaatagtaaa tatcttggca aggtggattc ttcgcaaaag catatttttg aaatgggtaa
    35401 aaccaaaact tttggagata tcgacatcga gagttttggt gtaagccatg atgcagtcgc
    35461 accgcagttc tatcgcttta tgaaggatga caagagtttt gtccttttga cagatacagg
    35521 ttatgtcagt gaccgtatgg cgggcattgt cgaaaatgcg gatggctatc ttatcgaggc
    35581 caaccatgat gtagagattt tgcgatcagg ttcttacgct tggcgactca aacaacgaat
    35641 cctatctgac cttggtcacc tttctaacga ggacggtgct gaagctatga ttcggacgct
    35701 aggaaatcgt actaagaaga tttaccttgg gcatttatct aaggaaaaca atatcaagga
    35761 actggctcat atgaccatgg tcaatcagct ggctcaagct gatctgggag tcggagtaga
    35821 ctttaaggtt tatgatacct caccagatac cgcaacacca ttgacagaga tatagaaaga
    35881 acgctgagaa ggtgttc
//
LOCUS       DAVKZI010000020        34492 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKZI010000020 DAVKZI010000000
VERSION     DAVKZI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.020"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            211..2862
                     /locus_tag="VXB18_001153"
     CDS             211..2862
                     /locus_tag="VXB18_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEV0382362.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTTVETKEASTPL
                     DVVILLDNSNSMSNIRHNHAHRAEKAGEATRALVDKITSNPDNRVALVTYGSTIFDGS
                     EATVEKGVADANGKILNDSALWTFDRTTFTAKTYNYSFLNLTSDPTDIQTIKDRIPSD
                     AEELNKDKLMYQFGATFTQKALMTADDILTKQARPNSKKVIFHITDGVPTMSYPINFK
                     YTGTTQSYRTQLNNFKAKTPNSSGILLEDFVTWSADGEHKIVRGDGESYQMFTKKPVT
                     DQYGVHQILSITSMEQRAKLVSAGYRFYGTDLYLYWRDSILAYPFNSSTDWITNHGDP
                     TTWYYNGNMAQDGYDVFTVGVGVNGDPGTDEATATRFMQSISSSPDNYTNVADPSQIL
                     QELNRYFYTIVNEKKSIENGTITDPMGELIDFQLGADGRFDPADYTLTANDGSSLVNN
                     VPTGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSNKFY
                     DTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPEITIPKEKKLGEIEFIKINKNDKKP
                     LRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENSEPA
                     GYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREYPRT
                     GGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            3095..5029
                     /locus_tag="VXB18_001154"
     CDS             3095..5029
                     /locus_tag="VXB18_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEV0382363.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAADNVSTAPDAVTKTL
                     TIHKLLLSEDDLKTWDTNGPKGYDGTQSSLKDLTGVVAEEIPNVYFELQKYNLTDGKE
                     KENLKDDSKWTTVHGGLTTKDGLKIETSTLKGVYRIREDRTKTTYVGPNGQVLTGSKA
                     VPALVTLPLVNNNGTVIDAHVFPKNSYNKPVVDKRIADTLNYNDQNGLSIGTKIPYVV
                     NTTIPSNATFATSFWSDEMTEGLTYNEDVTITLNNVAMDQADYEVTKGINGFNLKLTE
                     AGLAKINGKDADQKIQITYSATLNSLAVADIPESNDITYHYGNHQDHGNTPKPTKPNN
                     GQITVTKTWDSQPAPEGVKATVQLVNAKTGEKVGAPVELSENNWTYTWSGLDNSIEYK
                     VEEEYNGYSAEYTVESKGKLGVKNWKDNNPAPINPEEPRVKTYGKKFVKVDQKDTRLE
                     NAQFVVKKADSNKYIAFKSTAQQAADEKAAATAKQKLDAAVAAYTNAADKQAAQALVD
                     QAQQEYNVAYKEAKFGYVEVAGKDEAMVLTSNTDGQFQISGLAAGTYKLEEIKAPEGF
                     AKIDDVEFVVGAGSWNQGEFNYLKDVQKNDATKVVNKKITIPQTGGIGTIIFAVAGAA
                     IMGIAVYAYVKNNKDEDQLA"
     gene            5076..6257
                     /gene="rrgC"
                     /locus_tag="VXB18_001155"
     CDS             5076..6257
                     /gene="rrgC"
                     /locus_tag="VXB18_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HEV0382364.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDDRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNY
                     RFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            6595..7497
                     /gene="srtC-1"
                     /locus_tag="VXB18_001156"
     CDS             6595..7497
                     /gene="srtC-1"
                     /locus_tag="VXB18_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEV0382365.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            7484..8377
                     /gene="srtC-2"
                     /locus_tag="VXB18_001157"
     CDS             7484..8377
                     /gene="srtC-2"
                     /locus_tag="VXB18_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEV0382366.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEDILQKGAGLLEGASLPVGGKNTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            8364..9215
                     /gene="srtC-3"
                     /locus_tag="VXB18_001158"
     CDS             8364..9215
                     /gene="srtC-3"
                     /locus_tag="VXB18_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HEV0382367.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9288..10564)
                     /locus_tag="VXB18_001159"
                     /pseudo
     CDS             complement(9288..10564)
                     /locus_tag="VXB18_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(10679..10819)
                     /locus_tag="VXB18_001160"
     CDS             complement(10679..10819)
                     /locus_tag="VXB18_001160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382368.1"
                     /translation="MKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVDAFM
                     AL"
     gene            complement(10821..11105)
                     /locus_tag="VXB18_001161"
     CDS             complement(10821..11105)
                     /locus_tag="VXB18_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382369.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(11717..11887)
                     /locus_tag="VXB18_001162"
     CDS             complement(11717..11887)
                     /locus_tag="VXB18_001162"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0382370.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            complement(12704..13927)
                     /locus_tag="VXB18_001163"
     CDS             complement(12704..13927)
                     /locus_tag="VXB18_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0382371.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            14095..15417
                     /locus_tag="VXB18_001164"
     CDS             14095..15417
                     /locus_tag="VXB18_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0382372.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMVVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            15419..17305
                     /locus_tag="VXB18_001165"
     CDS             15419..17305
                     /locus_tag="VXB18_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0382373.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEISGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            17473..17817
                     /locus_tag="VXB18_001166"
     CDS             17473..17817
                     /locus_tag="VXB18_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0382374.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            17827..19239
                     /gene="lacG"
                     /locus_tag="VXB18_001167"
     CDS             17827..19239
                     /gene="lacG"
                     /locus_tag="VXB18_001167"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0382375.1"
                     /translation="MENLQFKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGDANILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLDRENIDHFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKTGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            19308..20987
                     /locus_tag="VXB18_001168"
     CDS             19308..20987
                     /locus_tag="VXB18_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0382376.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(21112..22551)
                     /locus_tag="VXB18_001169"
     CDS             complement(21112..22551)
                     /locus_tag="VXB18_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0382377.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLIFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(22555..23904)
                     /gene="trkA"
                     /locus_tag="VXB18_001170"
     CDS             complement(22555..23904)
                     /gene="trkA"
                     /locus_tag="VXB18_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0382378.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            24093..24941
                     /locus_tag="VXB18_001171"
     CDS             24093..24941
                     /locus_tag="VXB18_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0382379.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            24956..25504
                     /locus_tag="VXB18_001172"
     CDS             24956..25504
                     /locus_tag="VXB18_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0382380.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            25511..25723
                     /locus_tag="VXB18_001173"
     CDS             25511..25723
                     /locus_tag="VXB18_001173"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382381.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            25825..27507
                     /locus_tag="VXB18_001174"
     CDS             25825..27507
                     /locus_tag="VXB18_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382382.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRII
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            27492..28322
                     /locus_tag="VXB18_001175"
     CDS             27492..28322
                     /locus_tag="VXB18_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0382383.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            28515..29018
                     /locus_tag="VXB18_001176"
     CDS             28515..29018
                     /locus_tag="VXB18_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0382384.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      29072..29306
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            29471..30034
                     /locus_tag="VXB18_001177"
     CDS             29471..30034
                     /locus_tag="VXB18_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0382385.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            30048..30674
                     /locus_tag="VXB18_001178"
     CDS             30048..30674
                     /locus_tag="VXB18_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0382386.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKEPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            30702..31091
                     /locus_tag="VXB18_001179"
     CDS             30702..31091
                     /locus_tag="VXB18_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0382387.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            31096..31545
                     /locus_tag="VXB18_001180"
     CDS             31096..31545
                     /locus_tag="VXB18_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382388.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            31673..32260
                     /locus_tag="VXB18_001181"
     CDS             31673..32260
                     /locus_tag="VXB18_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0382389.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            32650..34257
                     /locus_tag="VXB18_001182"
     CDS             32650..34257
                     /locus_tag="VXB18_001182"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0382390.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT        10519 a         5779 c         7610 g        10584 t
ORIGIN      
        1 tatacaagtg tgtcattgcc aggttgagaa gatagctata acgcactttt atacgctttt
       61 gctacgtttg ttagtgaacg gattaactca gtgagataaa ttttatcaga acataagtaa
      121 tccgtttctt cgtgtataca gattgaaagt acctatgaat catagaagga ttaacttgtt
      181 ctatgaataa tgcttaacag ggagacacac atgaaaaaag taagaaagat atttcagaag
      241 gcagttgcag gactgtgctg tatatctcag ttgacagctt tttcttcgat agttgcttta
      301 gcagaaacgc ctgaaaccag tccagcgata ggaaaagtag tgattaagga gacaggcgaa
      361 ggaggagcgc ttctaggaga tgccgtcttt gagttgaaaa acaatacgga tggcacaact
      421 gtttcgcaaa ggacagaggc gcaaacagga gaagcgatat tttcaaacat aaaacctggg
      481 acatacacct tgacagaagc ccaacctcca gttggttata aaccctctac taaacaatgg
      541 actgttgaag ttgagaagaa tggtcggacg actgtccaag gtgaacaggt agaaaatcga
      601 gaagaggctc tatctgacca gtatccacaa acagggactt atccagatgt tcaaacacct
      661 tatcagatta ttaaggtaga tggttcggaa aaaaacggac agcacaaggc gttgaatccg
      721 aatccatatg aacgtgtgat tccagaaggt acactttcaa agagaattta tcaagtgaat
      781 aatttggatg ataaccaata tggaatcgag ttgacggtta gtggtaaaac gacggttgaa
      841 acgaaagaag cctctactcc gctagatgtt gttattctat tagataactc caatagtatg
      901 agtaatattc gacataatca tgcccatcga gcggaaaaag cgggagaagc gacacgagcc
      961 cttgtagata agattacctc caatccagat aatcgagtag cacttgtgac ttatggctca
     1021 actatctttg acggttcaga agctactgtg gaaaaagggg tagcagatgc gaacggaaaa
     1081 atattgaatg actcagcttt atggacgttc gatcgtacga cgtttacagc taaaacttat
     1141 aattatagct ttttaaatct cacatcagat cctactgata ttcaaactat taaggatagg
     1201 attccatcag atgcagagga attgaacaaa gacaaattga tgtatcaatt cggcgcgact
     1261 tttacccaga aggctttgat gaccgctgat gatatcttga caaagcaggc aagaccaaac
     1321 agtaaaaagg ttattttcca cattacagat ggtgttccga ctatgtcata tccaattaat
     1381 tttaaatata caggaacgac gcaatcgtac agaactcagc tgaataattt taaagcaaaa
     1441 actccaaata gtagcgggat attactggag gactttgtta catggtcagc agatggtgaa
     1501 cataagattg ttcgtggaga tggtgaaagt tatcagatgt ttacgaagaa acctgtaaca
     1561 gaccaatacg gagttcatca aatactttca atcacctcca tggagcagag agctaaatta
     1621 gtttcagcgg gatataggtt ctatggaact gacttgtatt tatattggcg tgatagtatt
     1681 ctagcctatc catttaactc tagtaccgat tggattacca accatggtga ccctacgact
     1741 tggtattata acggaaatat ggctcaggat ggctatgatg tcttcactgt tggggttggt
     1801 gtaaacgggg atcctggtac ggatgaagca acggctacta gatttatgca gagcatctct
     1861 agttctcctg acaactacac taacgtagca gatccatctc agattttaca agaattgaat
     1921 cgctacttct atactatcgt caatgagaag aaatctatcg aaaatggtac gattacagac
     1981 ccgatgggtg aactaattga tttccaattg ggagcagatg gaaggtttga tccagcggat
     2041 tacactttaa ctgcaaacga tggtagttcg ttggtgaata atgtccctac tgggggacca
     2101 caaaatgatg gtggcttgct aaaaaatgca aaagtgttct atgatacgac tgagaaaagg
     2161 attcgtgtaa caggtttgta ccttggaacg ggtgaaaaag ttacattgac ttataatgtt
     2221 cgcttgaatg accaatttgt aagcaataaa ttctatgaca cgaatggtcg aacaacccta
     2281 caccctaagg aagtagaaaa gaacacagtg cgcgacttcc cgattcctaa gattcgtgat
     2341 gtacgaaagt atccagaaat cacaattcca aaagagaaaa aacttggtga aattgagttt
     2401 attaagatca ataagaatga taaaaaacca ctgagagatg cggtctttag tcttcaaaaa
     2461 caacatccgg attatccaga tatttatgga gctattgatc aaaatggcac ttatcaaaat
     2521 gtgagaacag gtgaagatgg taagttgacc tttaaaaatc tgtcagatgg gaaatatcga
     2581 ttatttgaaa attctgaacc agctggttat aaacccgttc aaaataagcc tatcgttgcc
     2641 ttccaaatag taaatggaga agtcagagat gtgacttcaa tcgttccaca agatatacca
     2701 gcgggttacg agtttacgaa tgataagcac tatatcacaa atgagccaat tcctccaaaa
     2761 agagaatatc ctcgaactgg tggtatcgga atgttgccat tctatctgat aggttgcatg
     2821 atgatgggag gagttctatt atacacacgg aaacatccgt aaagtgtagc aatgagaaat
     2881 gataatatcg atactctgag cgatactttt aagaagtagc actcaagaag agatttaagt
     2941 ttacttggtg aaaacagttt tcttcgccaa gtaaaccacc attgaaaggg gagatgtttt
     3001 cgaaaacttg cacagaaaaa aggattatta ttgtcatgtg taattcatta cattgctcac
     3061 agttgatttt aagagatatg aataaggaga aatcatgaaa tcaatcaaca aatttttaac
     3121 aatgcttgct gccttattac tgacagcgag tagcctgttt tcagctgcaa cagtttttgc
     3181 ggcggacaat gttagtacag caccagatgc tgttactaaa actttaacaa tccataagtt
     3241 actgctctca gaagatgatt taaagacttg ggatacaaac ggtcctaaag gatatgatgg
     3301 aactcaatct agtttaaaag atttaactgg agttgtagct gaggaaattc caaatgtata
     3361 ctttgaatta caaaagtata atttgactga tggtaaggaa aaagaaaatc ttaaagatga
     3421 tagtaaatgg acaacagttc atggtggttt gacaactaaa gatggactta aaattgaaac
     3481 cagtactctt aaaggtgtgt atcgtattcg tgaggataga acaaagacta cctatgttgg
     3541 tcctaatggg caagtattaa caggttcaaa agccgtacct gctcttgtaa ctcttccact
     3601 tgttaacaat aatggtacag taattgatgc acatgttttc cctaaaaatt catataataa
     3661 accagttgta gataaaagaa ttgctgatac tttgaattat aacgatcaaa atggtctgtc
     3721 tatcggtact aaaatcccat atgttgttaa tacaacaatt ccaagtaatg caacatttgc
     3781 aacttcattt tggtcagatg aaatgacaga aggtctaact tataatgaag atgtaacaat
     3841 tactttgaat aatgtagcta tggatcaagc tgattatgaa gtcactaaag gaattaatgg
     3901 ctttaactta aaattaacag aagcaggttt agctaaaatt aatggtaagg atgcagacca
     3961 aaaaatccaa attacttact cagctacttt gaactcactt gctgttgcag acattcctga
     4021 aagtaacgat attacatatc attacggaaa tcatcaagat catgggaata ctccaaaacc
     4081 aactaaacct aataatggtc aaattacagt aactaagaca tgggacagtc aacctgctcc
     4141 tgagggggtg aaagcgactg ttcaacttgt aaatgccaag actggtgaga aagtcggtgc
     4201 tcctgtagaa ctttcagaaa ataattggac atatacttgg agtggtctag ataattctat
     4261 tgaatacaaa gttgaagaag aatataatgg atactcagct gaatacacag tagagagcaa
     4321 agggaagttg ggggtaaaaa actggaaaga taataaccca gctccaatca atcctgaaga
     4381 accacgtgta aaaacatacg gtaaaaagtt tgtcaaagta gaccaaaaag atactcgtct
     4441 agaaaatgcg cagttcgttg ttaaaaaagc agatagcaat aaatatattg cctttaagtc
     4501 aactgcacaa caagctgcag atgaaaaagc agcagcaact gcaaaacaaa aattggatgc
     4561 agcggtagca gcttacacaa atgctgcaga taagcaagcc gctcaagctc tagtagatca
     4621 agcacagcaa gaatacaatg tagcttacaa agaagccaaa tttggttatg ttgaagtagc
     4681 tggaaaagat gaagcaatgg ttcttacttc taatacggat ggtcaattcc aaatttcagg
     4741 tcttgctgct ggtacttata aattagaaga aattaaagct ccagaaggtt ttgcgaaaat
     4801 tgatgatgta gaatttgttg ttggagcagg ttcttggaat caaggtgagt ttaattactt
     4861 aaaagatgtt caaaagaatg acgctacaaa agtagtcaac aaaaaaatca ctatcccaca
     4921 aacgggtggt attggtacaa ttatctttgc tgtagcgggg gctgcgatta tgggtattgc
     4981 agtgtacgca tatgttaaaa acaacaaaga tgaggatcaa cttgcttaag taagagagaa
     5041 aggagccatt gatgacaatg cagaaaatgc agaaaatgat tagtcgtatc ttctttgtta
     5101 tggctctgtg tttttctctt gtatggggtg cacatgcagt ccaagcgcaa gaagatcaca
     5161 cgttggtctt gcaattggag aactatcagg aggtggttag tcaattgcca tctcgtgatg
     5221 gtcatcggtt gcaagtatgg aagttggatg attcgtattc ctatgatgat cgggtgcaaa
     5281 ttgtaagaga cttgcattcg tgggatgaga ataaactttc ttctttcaaa aagacttcgt
     5341 ttgagatgac cttccttgag aatcagattg aagtatctca tattccaaat ggtctttact
     5401 atgttcgctc tattatccag acggatgcgg tttcttatcc agctgaattt ctttttgaaa
     5461 tgacagatca aacggtagag cctttggtca ttgtagcgaa aaaaacagat acaatgacaa
     5521 caaaggtgaa gctgataaag gtggatcaag accacaatcg cttggagggt gtcggcttta
     5581 aattggtatc agtagcaaga gatggttctg aaaaagaggt tcccttgatt ggagaatacc
     5641 gttacagttc ttctggtcaa gtagggagaa ctctctatac tgataaaaat ggagagattt
     5701 ttgtgacaaa tcttcctctt gggaactatc gtttcaagga ggtggagcca ctggcaggct
     5761 atgctgttac gacgctggat acggatgtcc agctggtaga tcatcagctg gtgacgatta
     5821 cggttgtcaa tcagaaatta ccacgtggca atgttgactt tatgaaggtg gatggtcgga
     5881 ccaatacctc tcttcaaggg gcaatgttca aagtcatgaa agaagaaagc ggacactata
     5941 ctcctgttct tcaaaatggt aaggaagtag ttgtaacatc agggaaagat ggtcgtttcc
     6001 gagtggaagg tctagagtat gggacatact atttatggga gctccaagct ccaactggtt
     6061 atgttcaatt aacatcgcct gtttccttta caatcgggaa agatactcgt aaggaactgg
     6121 taacagtggt taaaaataac aagcgaccac ggattgatgt gccagataca ggggaagaaa
     6181 ccttgtatat cttgatgctt gttgccattt tgttgtttgg tagtggttat tatcttacga
     6241 aaaaaccaaa taactgatat tcaatgtaca tcattatgaa aaagatagca ggctgaaggg
     6301 aagaccagag tactctgagg tgatgttaat caggaatcat ggtgatgtgg catgaatcac
     6361 aataacggat atgaggctgg gcagattgtg ccagcctcat tgtgggttat tgtttgtaaa
     6421 acgataggac tggtctggta atcattttag gaatggacag gactgggatt ctgatttaaa
     6481 atggatggtg aatcagaaag aaatgagatt ttctcgtttc tcttagcaga taggattgtc
     6541 tgttaggaaa agcgataaaa tgatgagttt gaagataaag ggatgctgat aaaaatggta
     6601 aaaacaaaaa agcaaaaacg aaataatctc ctattaggag tggtattttt cattggaatg
     6661 gcggtaatgg cgtatccgct ggtgtctcgc ttgtattatc gagtggaatc aaatcaacaa
     6721 attgctgact ttgataagga aaaagcaacg ttggatgagg ctgacattga tgaacgaatg
     6781 aaattggcac aagccttcaa tgactctttg aataatgtag tgagtggcga tccttggtcg
     6841 gaagaaatga agaaaaaagg gcgagcagag tatgcacgta tgttagaaat ccatgagcgg
     6901 atggggcatg tggaaatccc cgttattgac gtggatttgc cggtttatgc tggtactgct
     6961 gaagaggtat tgcagcaagg ggctgggcat ctagagggaa cttctctgcc gatcggaggc
     7021 aattcgaccc atgcggtgat tacggcacat acaggtttgc caacagctaa gatgtttacg
     7081 gatttgacca aacttaaagt tggggataag ttttatgtgc acaatatcaa ggaagtgatg
     7141 gcctatcaag tggatcaagt aaaggtgatt gagccgacga actttgatga tttattgatt
     7201 gtaccaggtc atgattatgt gaccttgctg acttgtacgc catacatgat caatacccat
     7261 cgtctattgg ttcgggggca tcggataccg tacgtagcag aggttgagga agaatttatt
     7321 gcagcaaaca aactcagtca tctctatcgc tacctgtttt atgtggcagt tggtttgatt
     7381 gtgattcttt tatggattat tcgacgcttg cgcaagaaga aaaaacaacc ggaaaaggct
     7441 ttgaaggcgc tgaaagcagc aaggaaggaa gtgaaggtgg aggatggaca acagtagacg
     7501 ttcacgaaaa aaaggcacaa aaaagaagaa acatccgctg atccttcttc tgattttctt
     7561 agtaggattc gccgttgcga tatatccatt ggtgtctcgt tattattatc gtattgagtc
     7621 aaacgaggtt attaaagagt ttgatgagac ggtttcccag atggataagg cagaacttga
     7681 ggagcgttgg cgcttggctc aagccttcaa tgcgaccttg aaaccatctg aaattcttga
     7741 tccttttaca gagcaagaga aaaagaaagg cgtctcagaa tatgccaata tgctaaaggt
     7801 ccatgagcgg attggctatg tggaaattcc tgcgattgat caggaaattc cgatgtatgt
     7861 cggaacgagt gaggacattc ttcagaaagg ggcagggctg ttagaagggg cttcgctgcc
     7921 tgttggaggt aaaaataccc atacagtgat cactgctcac agaggattgc caacggcaga
     7981 attgttcagt caattggata agatgaaaaa aggggatatc ttttatcttc acgttttaga
     8041 tcaggtgttg gcctaccaag tggatcagat agtgacggtg gagccgaatg actttgagcc
     8101 tgtcttgatt caacatgggg aagattatgc gaccttgttg acttgtacac cgtatatgat
     8161 taacagtcat cgtctgttgg tacgtgggaa gcggattccg tatacggcac caattgcaga
     8221 gcggaatcga gcggtgagag agcgtgggca attctggttg tggttattac taggagcgat
     8281 ggcggtcatc cttctcttgc tgtatcgcgt gtatcgtaat cgacggattg tcaaaggact
     8341 agaaaagcaa ttggaggggc gtcatgtcaa ggactaaact acgagcctta ttgggatact
     8401 tgttgatgtt ggtagcctgt ttgattccta tttattgttt tggacagatg gtgttgcagt
     8461 ctcttggaca ggtgaaaggt catgctacat ttgtgaaatc catgacaact gaaatgtacc
     8521 aagaacaaca gaaccattct ctcgcctaca atcaacgctt ggcttcgcaa aatcgcattg
     8581 tagatccttt tttggcggag ggatatgagg tcaattacca agtgtctgac gaccctgatg
     8641 cagtctatgg ttacttgtct attccaagtt tggaaatcat ggagccggtt tatttgggag
     8701 cagattatca tcatttaggg atgggcttgg ctcatgtgga tggtacaccg ctgcctctgg
     8761 atggtacagg gattcgctca gtgattgctg ggcaccgtgc agagccaagc catgtctttt
     8821 tccgccattt ggatcagcta aaagttggag atgctcttta ttatgataat ggccaggaaa
     8881 ttgtagaata tcagatgatg gacacagaga ttattttacc gtcggaatgg gaaaaattag
     8941 aatcggttag ctctaaaaat atcatgacct tgataacctg cgatccgatt cctaccttta
     9001 ataaacgctt attagtgaat tttgaacgag tcgctgttta tcaaaaatca gatccacaaa
     9061 cagctgcagt tgcgagggtt gcttttacga aagaaggaca atctgtatcg cgtgttgcaa
     9121 cctctcaatg gttgtaccgt gggctagtgg tactggcatt tctgggaatc ctgtttgttt
     9181 tgtggaagct agcacgttta ctacgaggga aataaaaaga aatgaaagga aagctaaggc
     9241 tgttcctttt tccggctctt tgtcaactgt agtgggttga aaaaaagcta agctcgagaa
     9301 aggacaaatt ttgtcctttc ttttttgata ttcagagcga taaaaatccg ttttttgaag
     9361 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     9421 gcttccagtt tggcattaga atagtgtagt tgaagggcgt tgataatctt ttctttatct
     9481 ttgaggaagg ttttaaagac agtctgaaaa ataggatgaa cctgcttaag attgtcctca
     9541 ataagtccga aaaatttctc tggttcctta ttctggaagt gaaaaagcaa gagctgatag
     9601 agttgatagt ggtgtttcaa gtcttccgaa tagctcaaaa gcttgtttaa aatctcttta
     9661 ttggttaagt gcatacgaaa aataggacga taaaatcgct tatcactcag tttacggcta
     9721 tcctgttgaa tgagtttcca gtagcgcttg atagccttgt attcatggga ttttcgatga
     9781 aactgattca tgatttgaac acgcacacga ctcatagcac ggctaagatg ttgtacaatg
     9841 tgaaagcgat caagaacgat tttagcacac gggaaaagtt gtctagctaa gtcatagtaa
     9901 ggactaaaca tatccatagt aatgattttg acgcgacatc ggacggctct atcatattta
     9961 agaaagtgat ctcggatgac agcttgtgtt ctaccttcaa gaacagtgat gatattgaga
    10021 ttgttaaaat cttgcgcaat aaagctcatc tccatctccc gattgaaaca gtcactcccc
    10081 ggactgtttc aacgtcccag gacataatct caggaagacg cgaaaaatca tgctcaaagt
    10141 gagaatcatt gagcttgcga atgacagttg aagttgaaat ggccagctga tgagcaatat
    10201 cggtcataga aatcttctca atcaactttt gcgcaatttt ttggttggta atacgaggaa
    10261 tttgatgatt cttcttgacg atagaagttt cagcgaccat catttttgaa cagtgatagc
    10321 acttgaaacg gcgttttcta aggagaattc tagtaggtat accagtcgtt tcaagataag
    10381 gaattttaga aggtttttga aagtcatatt tcttcaattg gtttccgcac tcagggcaag
    10441 atggggcgtc gtagtccagt ttggcgatga tttccttgtg tgtatcctta ttgatgatgt
    10501 ctaaaatctg gatattaggg tctttaatgt ctagtaattt tgtgataaaa tgtaattgtt
    10561 ccatatgatt ctttctaatg agttgttttg tcgcttttca ttataggtca tatgggactt
    10621 tttttctaca caaaaatagg ctccataata tccatagggg atttacccac tacaaatatt
    10681 atagagccat aaaagcatca acatcttgtg tggcacgtaa accatgatat tctaagacat
    10741 aaccatcgac acagataatt gttaaagtca gattttcctg aattaattcc ttatttaggg
    10801 cttggaagac cggtttcatt ttatccatgt ttgtatttct ccatcaattt ttgaacattg
    10861 gttaacttag caggtttatt taatgaaatc acatatttat gagttggagt atgctcttga
    10921 aaggcatact tcaagctaat tttttgaaaa cgggttagtt ctttggagtc tagcaacttt
    10981 tctacatctt ggtttgttaa ataagaatag tcttcaaaaa taacttttcg caaatagcga
    11041 aaccaatggc ttgcgttgaa ttgtgattgt ttggatgcct gtatcatata atcgtaccaa
    11101 tccattgtct tcctcctata aaatttagtt tatattattg tagtttatat tcgaaaatgt
    11161 agtttttctt aattagctcg tatctatagg atgatactga aaatcttctt gttgctttaa
    11221 atcacaatcg aaaaattctg tttttcatct tagaaaagaa tgtttagaaa tgtaaaatga
    11281 atcttttttc ttatccgaaa acattactaa agtatataat ttaggaagtc aattctgtat
    11341 gataatgttt gtactatcgt cgagtttttg cttgattgcc taacgagata aattttagaa
    11401 gaattttcgg tgtgatttga caagcttctg actggaagga tagttacact agtattgttt
    11461 attaaaatga gcagatagag aaaatttgga atctatttgc ttattatcaa tcgttttttt
    11521 agcttatttg tcttagattg gtatagaact gatctatgga ttaatcctct tgtatcttat
    11581 cctgttccta aatatgttgg tagaaaaatg aagcagttgt tacgagtgtc tgtattggga
    11641 aaaattttgt ctatacaatt ctttaaatga tatgaaggct aggaatgcca aaacactgac
    11701 atatttcgtt taaagcctat ccagcctttt caattgtatt tgtagaaatg ctatcagtaa
    11761 tatattcgcg aacactatga tttacaacag tgtggtcgta catctttgta actttattat
    11821 acaacaacca tttacaggtg taaagttgag cagtgtcttt agtaaattta gggacttgtt
    11881 ttgtcatagt tttgatacct gtattcgttg tttcatgagc atttgacgtt tcttttcatg
    11941 taggcatttc aacaattaga atgatatttt tccgaggatg aacttatata ttgtgacttt
    12001 ttagagttat gatgcctctt gatttgacta tcgctatcaa tttcatccac ttttacagtt
    12061 tcatggtttt atgaaccgaa acatctaggt acaggtttta gcatcaattg attgtttttg
    12121 agccatatga agttgaaacg tggagatgct tttcttgtga taacgcccta ttcaaagagg
    12181 cataaccgtt tttggagaga gttcagtact atgtggcgct aaataatata tgtaaaatag
    12241 tatggtgtag agatattaaa caagatttaa ctaatacttt tcgaaaatct cttcaaacca
    12301 cgtcagcgtc gccttaccgt atagatgtta ctgacttcgt cagttctatc tacaagctca
    12361 aaacagtgtt ttgagcagcc tgcagctagc ttcctagttt gctctttgat tttcattgag
    12421 tatacggaga attgtaaaaa caaaaatggg gatttcatat aaagtttatt ctaggagtat
    12481 gtatcttgaa taaaaattgt tatttaagtt ctgggggtta tgatgaatgt ttttataata
    12541 ataaaatgca gctagaagaa aagttatttt aatataaatc actcaacata gcgagaaggc
    12601 ggtttcctat atggaagtcg tcttgttttc atattgtcta aatacgagat atctactaca
    12661 ggttatagtt gatttaaaca ggtgtataga tttctaatat atattaaggt gaaataatat
    12721 cttgtaatac attgctatgc tctatgaaaa aagcaacgat agctaatgca caagctccta
    12781 tacttccacg atgtttgttg taaggtaaaa tttcaatttc tatattacga gtaaagggaa
    12841 cgaagtggag ctggtcttgg attttatccc tgacttcatg agtgaaaggt tgataattaa
    12901 gcaattgact gttgatatag attttatcag caggattgat gaggagaaga tttgcaatag
    12961 aagtggccaa taaattgact cctttatcaa tttgttggcg taaagcggag tcgcctaaat
    13021 tataagccgt taaaagggtg tctaaatgaa tgtctttttc agtctttaca aggcttttta
    13081 gtacagttag ttgggaattt ttaaataata attgggcgtg tttgattaac caagcatccg
    13141 aaatatatgt ttgtaaacaa cctttttttc cgcattcaca atattgccca ttcaattcga
    13201 caatggtgtg tccaatttct ccgatataag gatttttaga ggctcctatt ttttcttttg
    13261 tgaaaaagga agtgtaaata cctaatccag cgtgtaggaa aataaagtta tcgggggtat
    13321 tgtgtggatt aaaaaggtat tgtcctatag ccatacaatc gatattattt tttacaataa
    13381 aaggaaaatt gaatctttta attacattta ataaattaaa agattcccat atggggttgt
    13441 ttgtaatgat acttccggag tctttgttat aatgtccagg tattgataag ccaaatccaa
    13501 gtaattttgt ttccaaaggg acgtactcta tagctgtttt tatcatattg gtaatggtgg
    13561 aattgatttc tgaaatagga taatcttcat tcaaaatttc tgtctcgaaa agagttttcc
    13621 cttgtaagtc acatagactg agaaagatac ctaggacgtt tatttcaata cctccaacaa
    13681 catacggaat attatctgtg atagaaatag tttttctacg tcttccagat ccggaaaact
    13741 cgctaaattc atcaccagtt tcgtatatga gggactgttc gcttagctct tttatgatgt
    13801 tagtcgttgt tgctggagta aggcctgttt cattaacaat atctgtacgg gatgttgctg
    13861 gatttcgata tagaaactcc agtatagtgg ctctattttg taaaaaggct gattgttttg
    13921 taatcatttg tttcctcctt tggtttattt tatattaaac ataagaaaaa atcaattaaa
    13981 attattattc tatacaaaga aaaaaatatt gtaaaaacaa caaaaaatat attgacaacg
    14041 ctttctgtta gtggtatatt taatttataa aaaataaaaa aaggagttcc ggtgatgaac
    14101 aatattttag cgtttttaga aacaaaagtc gctccgtttg gtgaaaaagt tggcaaccaa
    14161 cggcatttga aagctattcg tgaaggattt atgatggcaa tgcctttgat tttagtcggc
    14221 tctttatttc ttattctaat cagttggcct caagaggatt ttacaaattg gctgaatagt
    14281 gttggattgc taagtatctt gacaactatg aatcagtcaa cagtagcgat tatctccttg
    14341 gtcgcttgtt tcggtattgc ctacaggttg tcggaaggat atggtacaga tggtccgtcg
    14401 gcagggatca tagccttatc cagttttgta ttgatggcac ctcgtttttc gagtatggtt
    14461 tatgataaaa atggggagca ggtcaagcag ttatttggcg gcgcaatacc attttctagc
    14521 ctgaatgcat cttctttgtt tatggcgatt actattggat tggttacagc agagatttat
    14581 cgtatgttta tccagcgcgg aattacgata aaaatgccaa gtggtgtccc agatgtggta
    14641 agtaaatcat tttcagctct tttacctggc tttactactt ttgttttgtg ggctctggtc
    14701 ttaaaaggtc ttgaagcggc aggagttgca ggaggtctca acggactcct aggtgcaatt
    14761 gttggaacac cgcttaagtt aattgcagga acgcttccag gtatgattct atgtgttatt
    14821 gtaaactcat tcttttggtt ctgtggagtt aatgggggac aagttttaaa tgcttttgta
    14881 gatccagttt ggttacaatt tactacagaa aaccaagaag ctgtggctgc aggacaaaca
    14941 ctccaacaca ttattacatt accgtttaaa gatttatttg tatttattgg tggcggtgga
    15001 gcgactattg gtcttgcgat ttgtctcttc ctatttagta agagtcgtgc gaataaaaca
    15061 ttaggtaagc tagctattat accgtctatt tttaatatca atacagctat tctatttacg
    15121 tttccaacag ttttaaatcc gattatgctg attccgttta ttgctactcc tacaatcaat
    15181 gccttaatta cctatgtatc aatggttgta ggattagtac cctatacaac aggtgtaatc
    15241 cttccgtgga caatgccacc gatcatagga ggcttccttg cgacaggagc tagttggcga
    15301 ggagctctat tacaagttgt tttgattttg gtttctgtag caatttatta tccattcttc
    15361 aaaattgcag ataaacgcaa tcttgaaaaa gaaaaagcta ctgttggagg gaaataagat
    15421 ggttatcaga gtatttgata agcagaaaaa tacttattct agctttgcct tagaggaatt
    15481 aagttactat ataaatcggg tctttaagac tgacatagaa cttgtcgagg agaaggaagc
    15541 ggatattttt gtaggattag tcaataaaga ggatagaaga gaccatgttc ttatctcatt
    15601 agacaagggt aaggggagaa ttgagtctaa tacaattgta ggtttactta ttggaattta
    15661 ccgaatgttt catgaatttg gggttgtgta tactagacca gggcgcggac atgactttgt
    15721 tccagagtta cgatttgaag attttttaga taaacagcta tctatagatg aaacagccag
    15781 ttactatcat aggggagtat gtatagaggg agcggattca tttgaaaata tactagattt
    15841 cattgattgg ctacctaaga ttgggatgaa cagttttttc atccagtttg aaaatcccta
    15901 ctcttttttg aaacgttggt atgaacatga atttaatcca tatctaaata aagaacaatt
    15961 ttcaaatgaa ttagtacaag aattgagtga taggttggat aaagaattgc aaaaaagagg
    16021 tcttattcat catcgtgttg gtcatggatg gacaggtgaa gttttaggtt actcttcaaa
    16081 atttggctgg gaatcaggtc ttagtatttc agaggagaag aaaccctatg tcgctgaaat
    16141 aagcgggaaa cgagaattat ttaatacggc tccgatttta accagtctgg atttttcaaa
    16201 tccagatgtg gcggataaga tggtagaaat tatcaaggat tatgccaaga aaagacctga
    16261 tgttaactac ttacatgtat ggttgtcgga tgctcgtaat aatatttgtg aatgcgaaaa
    16321 ctgtagacaa gaattggttt cggatcagta tattcgtatt ctcaatcaat tggatagggc
    16381 tttaacgagt gagggattag atacaaagat ttgttttctg ctttaccatg agttgctatg
    16441 ggcgcctcag aaagaaaaat tagataatcc tgaacgcttt accatgatgt ttgcaccgat
    16501 tacaagaaca tttgaaatga gttatgcaga tgtagatttt gacaattcca tacctacgcc
    16561 taaaccttat ctgcgtaata aaattatact tccgaattct cttgaggaaa atttatctta
    16621 tctttttgag tggcaaaaaa catttaaagg agatagtttc gtatatgact atcctttagg
    16681 gcgtgctcat tatggcgatt taggctatat gaaaattagt caaaccattt acagagatgt
    16741 atcttatctt tctaacctac atttgaacgg ttacatttcg tgtcaagaat tacgtgccgg
    16801 attccctcat aattttccta attatgttat gggggaaatg ctctggaaga agacaagaag
    16861 ttatgaagaa ttgattgaag aatacttttc tgctttgtat ggggaaaatt ggcagtctgt
    16921 tgttgaatat ttagaaaaat tatccattta ttcctcttgt gattatttta atgcaattgg
    16981 cagccgtcaa agtgatgttt tagcgaatca ttattatata gcttacaatc tagctgataa
    17041 ttttttacca attattgagg aaaatatttc taagttatta aatagtcaaa aggatgaatg
    17101 gaaacagctc agttatcatc gtgaatatgt tgttaagatg gcgaaggctt tatatcttca
    17161 agcaactgga aaaacaaggc aagctcaaga tgaatggaga aatgtgttga attatatccg
    17221 tgggcacgaa ttgctatttc aatctaattt ggatgtttat cgtgtaattg aagtagcaaa
    17281 aaattacgct ggtttccact tataaatcat aagtatagaa aatgaactaa ggtattcaga
    17341 gaagattgac cctaaatatt atgaaattta aggattttta agatatttag ggtcgacttt
    17401 ctatttgtat cgtagcgaag tcattttaat aatgatgtgt aaaagatgga tcaagattga
    17461 ggaggaagaa agatgaaatc aaaagaagaa ataaatatgc ttggttttac aattgtcgct
    17521 tacgcaggag atgcaaggtc agatttgatg gatgctttgg cgtttgcgag agatggatat
    17581 tttgaacagg caagagaatt ggttgagtct gcaaacgact caatagtgtc tgcccatcga
    17641 gaacagacta atttattagc agaggaggca tatggagata attttgaagt gagctttatt
    17701 atgattcatg gtcaagatac tttgatgaca acgatgctat tgtatgatca ggtaaagttt
    17761 tttattgatg aatatgaacg aattcgaaag attgaagaac atattggttt gcaatgagga
    17821 ttagtcatgg aaaatttaca gtttaaagcc ttaccgaagg agtttttatt aggagctgct
    17881 accgctgctt atcaagtaga gggtgcaact agggtagatg gtaaaggaat aaatatgtgg
    17941 gatgtttatt tgcaagaaaa tagtccgttc ttaccagatc cagctagtga tttttattat
    18001 cgttacgaag aggatatagc tttggcggca gaacatggtt tgcaggcttt gcgtttatct
    18061 atttcttggg ttcgtatatt tcctgatata gatggagatg ctaatatatt ggctgttcgt
    18121 tattaccata gagtctttca gtcttgctta aaacataatg tgattccgtt tgtttcttta
    18181 catcattttg attcgcctca gaaaatgtta gaaacagggg attggttgga tagagagaat
    18241 attgatcatt tcatacgata tgctcgcttt tgtttccaag aatttacaga agtcaagcat
    18301 tggtttacaa tcaatgaact gatgtctctt gctgcaggtc aatatatagg aggtcagttt
    18361 cctccaaatc atcattttca attatctgaa gcaattcaag cgaatcataa tatgttgttg
    18421 gcgcatgctc ttgcagtcct cgaatttcat caattaggaa ttgagggaga gataggttgt
    18481 attcatgctt taaagccagg ctatcctatt gatgggcaaa aagaaaatat tttggcagct
    18541 aaacggtatg atgtttataa taataaattt ctattagatg gaactttttt gggctactac
    18601 agtgaggaca cgctttttca cttgaatcaa atattggaag ctaataattc tagctttatt
    18661 attgaagatg gtgatttaga aattatgaag agagctgcac ctcttaatac gatgtttggg
    18721 atgaattatt atcgttcaga atttattcgt gaatacaaag gtgaaaatag acaagaattt
    18781 aattcaacag gaataaaagg acagtcttct tttaaattaa atgctctagg tgaatttgta
    18841 aaaaaaactg gtattccgac aacagattgg gattggaata tttatcctca agggttattt
    18901 gatatgttgc ttcgtatcaa agaagaatat cctcaacatc cggtcattta tttaactgaa
    18961 aatggtacag cccttaaaga agttaagcca gagggcgaga atgatattat tgatgacagt
    19021 aagagaatcc gttatattga gcaacattta cacaaagttt tagaggctcg agatagagga
    19081 gtcaatattc aaggctattt tatatggtct ttgcaagatc aattttcttg ggcgaatggc
    19141 tacaataagc gatatggtct tttctttgtt gattatgaaa cacagaagag atatattaag
    19201 aaaagtgctc tttgggtaaa agggctaaaa cggaattaag gttagcgatt tgactgatgt
    19261 ttaatatgtt ttaaatatga ggttgaattt tttataggag gagttttatg gataagctag
    19321 tcgctgccat tgaaaagcaa caagggaaat ttgaaaaaat ttctactaat aactatatga
    19381 tggctattaa agatggattc attgctacta tgcctttaat tatgttttca agctttttga
    19441 tgattattat tatgattcct aaaaatttcg gagtagagtt accgagtcca gctattgtct
    19501 ggatgagaaa agtgtatatg ttaaccatgg gagttttggg tattattgtt tcagggactg
    19561 ttggaaagtc attagttgga aatgttaaca gaaaaatgcc tcacggaaag gtaataaatg
    19621 atacttctgc aatgttggca gccatatgta gttatctggt attaactgta acgcttgtag
    19681 ttgatgagaa gacgggatct acaagtttgt cgacaaacta tttaggatct caaggattga
    19741 taacttcgtt tgtcagtgcc tttattactg taaatgttta ccgattctgt attaagcgag
    19801 acattactat tcatttacct aaggaagttc ctggggctat atcacaagct tttagagata
    19861 tttttccttt ttcttttgtt ttacttatta gtggtttgtt agatattgta tctcggttta
    19921 gtttagatgt tccttttgcc caagtatttc aacaactatt gactcctatt tttaaggggg
    19981 cagaatcata tcctgctatg atgttgattt ggtttatgtg tgctttgctt tggtttgttg
    20041 gaattcatgg accatctatt gtcttacctg ctgttacagc tttacaactg agcaatatgg
    20101 aagagaatgc tcaacttctt gcaaatgggc agttccctta tcattcttta acacctaatt
    20161 tcgggaatta tatcgctgct attggaggaa cgggggctac ctttgttgta ccatttattt
    20221 tgattttctt tatgcggtct aaacaattaa aatcggtagg taaagctaca attactcctg
    20281 ttttatttgc ggtaaatgaa cctcttctat ttggtatgcc tgttattttg aatccctatc
    20341 tttttgtccc ttttttgatg actccaccag taaatgtatt tctaggaaag gtatttattg
    20401 atttctttgg aatgaatgga ttttatatcc agttaccttg ggcttttcct ggtcccttgg
    20461 gattgttaat tggaacgaat tttcaaccta tctcctttgt gcttttatct ttgatgttag
    20521 ttgtcgacat attgatttat ttgccattct gtagagcgta tgatagacag ttactgatga
    20581 aagaagatgt tgcaagctca aatgatatta ttttagagga ggatacaagt gaaataatgc
    20641 ctggtgagat agatgtaata aaaagtaagg agttgaaagt actggttctt tgtgcagggt
    20701 ctggaacaag tgcgcaatta gccaatgcaa ttaacgaggg cgctcaatta gcagaagtta
    20761 gagtgattgc gaattcagga gcgtacggag ctcattatga tattatgggt gtttatgatt
    20821 taattattct ggctccacaa gttcggagtt attatagaga gatgaaggtg gatgcagaaa
    20881 gattaggtat tcagatagtt gctaccagag gaatggaata tattcattta acaaagagtc
    20941 caagtaaatc cttacaattt gtattggagc attaccaagc tgtgtagtaa gtttttccat
    21001 cttttatttg agtaagaact ttgcttacag acaggcttgg atttaaaaac gttccccctt
    21061 tttaatataa aaatccctct ttcacaattg taaaaagagg gattttgtat tttatctttt
    21121 agaccaagtt ctcttcataa agagaagtag gattgggtaa atctccaagc ggcctgcaat
    21181 cattgcaaag gagaggagaa tttttgagat aggactaaag attgagaaac tagaagtggt
    21241 tcctagaata ggcccgatat tattgaaaca gctaaagaca gcgctggtca cgatcagaaa
    21301 atcattgcta tctaggctga caataaagat aagggatagc aaaatcatag catagatgac
    21361 aaagtacttg agaattttat gctgggtatc cttatcaatc accgttttat tcacatggag
    21421 agtcaaaaca cggtggggag atagaatgga caaaatttga tttttggcaa tttttgaaag
    21481 gatgaggcct cgaataatct tgagtccacc tgcagttgat ccagcagaac caccgattgt
    21541 catgaggaag aggaggataa actgggagaa gaggggccag ttggtaatat ctccatatcc
    21601 aaaaccagtt gttgtaatga tgttggaaac ctggaagaag gtcatttcaa agctctttga
    21661 aaaccctggg tagaggtaga gggtgttgag gctaatcaag cctgtagaaa ccagtacaat
    21721 gaccaagtaa gcccgaagtt cttcgtcacc aaagaaggcc ttgatgcgac ggagcatgag
    21781 gtagtagtag aggttgaaat ttaccccaaa aatcagaact ccgatactga ccagataggt
    21841 aatcagtgag ctgccatagt gggcaattcc gtcgttatag acggtaaagc ctccagttcc
    21901 cgctgtcccc atagcaatga caaaactatc gtagagaggc ataccagcta gataatagat
    21961 gatgacaaag agggagaaga gagctagata aaggagatag agaatctggg cagtgttttt
    22021 tagtttggat acaaccttgc caaaaacagg acctggaacc tcagccttca tcacctctag
    22081 gtggctattt ttggcattgt ccataatagc aagtgcaaaa acaagcactc ccatccctcc
    22141 aatcaagtgg gtaaaacttc tccagaagag gagggaacgg ctgagaaccg aaacgtcgtt
    22201 caaaatactt gctccagtag ttgtaaaccc agaactaatt tcaaaaaagg catcaataac
    22261 gctagggatt tgcccagaaa agacaaaggg gagaccacca aagaaagacc aaaggatcca
    22321 acagagggca acgatcaaga ctccctcctt ggcataaatc cgttgatttt ttggcttctg
    22381 taaactccct gaaccgccta acaatacgag aatccctatg gtcgaaaaga gggccgtaaa
    22441 gacttggctc gattcacggt aatagacagc gatagccaca ggaaccaaga ggagaacagc
    22501 ttcaatcaaa agtaactttg aaaggaggta acgaatcata cttttattca ttttttacct
    22561 cgcaatcaag tcataaatct tggtgatgtt tggcaacaag gttgttacta ggagcttgtc
    22621 tccaacttcc aacatatcct ccccagttgg gaaaatagtc ttgccctttc gaataatggc
    22681 tgcaataaga accccttttt tcaatttcag ttgagaaaga ggtttggcag tcattttatt
    22741 ggcttccttg atatggaatt gcagggtttc gatttggcca ttggctagat ggtgcatggc
    22801 ttgaaggtct gaatactggg cattaactcg accacgaata aagtgcataa tcgtatctac
    22861 agcgatgctt ttaggtgtga tgatacttga aaaatcaggc gcattgataa tctcgaggag
    22921 actggtacga ttgaccttag taatattttt ctgtacacct accctgtcaa ggaacataga
    22981 tgtaatcaga ttttcctcat cgacacctgt tagagtcgca acggcatcat agtgttgagc
    23041 actttcttcc agcaggatat cttttgcggt tccatctcct tgaacgatgt agagatttgg
    23101 gaatttctcg ctaaagaagc tggcgatttc aggattgatt tcaatgactt ttgtatcgat
    23161 acgactatct ttgagaatac caagtagata ataggcaatt ctacctgccc caacgatgag
    23221 aaggctcttc acggcgcgtg atttaaaata attatggaag agtatcatat cgacacggtt
    23281 accagtgaca aagattctat ctttatcctg tacagtcatg tcaccgcttg gaatgataat
    23341 ttgatgctcc ctctctatcg cacagacaat gacattacca aattttttac gaaaatcaga
    23401 aatgggcatt tggcaaagac cgctggtgga cttgacgaca aattccatga ggctaacgcg
    23461 tccaccagca aagcgttcga cagacagggc gttggggaag tcaatgatat tcgcgatagc
    23521 gcgggcagcc aagagctcag gattaacgat aagagaaaaa ccgagaatat tcttttcctt
    23581 gaaataagag ttagaatatt cagggttccg cacccgaacg atagtttctt tagctcccat
    23641 tttcttggct agaactgctg caatcatgtt gacttcatcg tgctcagtca gggcgataaa
    23701 gatatcacaa tcttggacgc tggcttgctc aagaatggca aaatcggccc cgttaccaag
    23761 gataccaatg atatcaaagc gactgacaat atgattgaga acagcttcgt cttgctcaat
    23821 cagcaaaaca tcatgctttt ctgcaaccaa ggagcgacag agggcaaaac caacttttcc
    23881 ccctccgaca aggataattt tcataataaa acctactttt tcatgatgta actatcatac
    23941 cctttttcaa gaaaaaatgc acctactagc taataaccag agtttttagt aggaaatttg
    24001 ctataagtta aaactatacc ctaaccaatt gaaatagcta ttagcgactt tctctgaaat
    24061 atggtatgat aaaggatata caaggagata aaatgaataa taatttactg gtattacaat
    24121 cagactttgg tctggttgat ggtgcggtat cggctatgat tggagtggct ttagaagagt
    24181 ctccaacctt aaaaatccat cacttgacgc acgatatcac gccttataat atttttgagg
    24241 ggagctatcg tctctttcag acggtggatt actggcctga gggaacgacg tttgtatcgg
    24301 ttgtcgatcc aggtgtcggt tcgaaacgta agagtgtagt tgccaagact gcaaaaaatc
    24361 aatacattgt cacgccagat aatgggacgc tttcctttat caagaaacac gttggcattg
    24421 tagccattcg tgagatttct gaggtggcca ataggcgtca aaacacagag cattcttata
    24481 ccttccacgg tcgtgatgtc tatgcctata ctggtgctaa actggccagt ggtcacatta
    24541 cttttgagga agtagggcca gagctcagtg tggaacagat tgtagagctt ccagtcgtag
    24601 cgaccatcat agaagatcat ctggtgaagg gagccattga tattctggat gtgcgtttcg
    24661 gttcgctttg gacctctatc acacgggaag aattttacaa gctggaacca gaatttggtg
    24721 atcgttttga agtgaccatc tatcatgctg atatgctggt ctatcaaaat caggttgtct
    24781 atggcaaatc atttgcagat gtgagaattg ggcaacccat cctttacatc aactctctct
    24841 atcgtttagg tttggctatc aaccaaggtt cctttgccaa ggcctataat gtaggtgtcg
    24901 gttcatcttg gaccattgaa ataaagaaaa tagaaggata aaataggaga atagtatgga
    24961 aatcaaattt acaattaaac aagttgttgc tgtcggaatt ggcgctgccc tctttgtcgt
    25021 catcgggatg atcaacattc caacccctgt tccaaataca agcatccagc ttcagtatgc
    25081 ggtacaagcg ctactttcta ttatttttgg accgattatc ggtttgcttg tcgggttgat
    25141 tggtcatgca atcaaggact ctcttgttgg ttatggtcta tggtggactt ggattatcgc
    25201 tagcggactc tttggtttag ttgtgggact ttttagaaag tacgttcgcg tgatcaatag
    25261 tgtttttgac tggaaagata ttcttatttt taatctcatt caactacttg caaatgccct
    25321 tgtttggggt gtcttggcac cacttggaga tgttgtgatt tatcaagaag cggcagaaaa
    25381 agtatttgca caagggattg ttgcgggaat tgccaatggt gtatctgtag ctattgcagg
    25441 aactcttctc ttacttgcct atgcaggaac ccaaactcgt gcaggaagtt tgaaaaagga
    25501 ctaatactca atgaaaatca aagagcaaac taggaagtta gccgcaggtt gctcaaaaca
    25561 gtgttttgag gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggcgaa
    25621 actgacgtgg tttgaagaga ttttcgaaga gtataaaatg atggggaagg ctgggcaact
    25681 agtctttttc gatgtttata gattagttag gcaagtaagc taggatagga atctttttgg
    25741 cgctaagatt ttaagagaag agactgcaag aagggcttga tttatgataa aatagaagtc
    25801 taagaagcga atgaagagag taagatgaaa gaagctataa ttgagtggaa ggatttctct
    25861 ttccggtatg aaacacaaca agaaccgacc ttgcaaggga tagacttgac catttacaag
    25921 ggagagaaag tcttaattgt tggaccatct ggatcaggta aatctacctt gggtcagtgt
    25981 ttgaatggga ttattcccaa tatttacaag ggtcagacat atggagaatt tttgataaag
    26041 ggtcaaacag cctttgatat gagcatctat gataagtctc atctggttag cacagttttg
    26101 caggatacag atgggcagtt tattggcttg tctgtggcag aagatttggc gtttgctctg
    26161 gaaaatgatg tgacagccct agatgagatg aaaggtcgtg tttataaatg ggctgaaaag
    26221 ctggaccttc ttcctttact ggatcagcgt cctcaggatt tgtcaggtgg acaaaagcag
    26281 cgagtcagtc tagctggtgt cttgattgat gaaagtccga ttctcttgtt tgatgagcca
    26341 ctcgccaatc tagatcccaa gtcaggtcag gatattatcg aattgattga ccagattcat
    26401 aaggaagagg ggacgacgac tctgattatc gagcaccgtt tggaggacgt tctgcatcgc
    26461 cctgtggatc ggattatctt gataaacgat ggtcgtatcc tttttaatgg gagccctgac
    26521 cagttgcttg cgactgattt attgactcaa aatggaattc gagaacccct ttatctaacg
    26581 actctccgtc aattaggtgt ggacttagtc aaggaagaac agttagcgaa tctggataac
    26641 atgtctatct caaaaggtca ggttcagctg cagaatgaac tggcaaaaga aactccagaa
    26701 ttgcagtcac tctttaaatt agaggacgtg tctttctctt atgatgatag accgatttta
    26761 aaatccctac atttagatat taaaaagggt gaaaagattg ctattgtcgg aaaaaatgga
    26821 gcagggaaat caactctagc caaggctata agtagcttta ttcagacgga aggacgctat
    26881 ctttgggaaa aacaggatat aaaaggcgat tctgttgcag agcgggcgga acgagtaggc
    26941 tatgtgctac aaaatcctaa tcaaatgatt tcaaccaata tgatttttga tgaggtggct
    27001 ctagggctcc gtttgcgagg tgtggatgag aaggaaattg aaacgagagt ctatgaaacc
    27061 ttgaaaatct gtggacttta tgaattccgt aattggccta tttctgccct gtcatttggt
    27121 cagaaaaaac gtgtcaccat tgcttcaatt ttggtcttag gagctgaaat tattctccta
    27181 gatgaaccga ctgcaggtca agatcagaag aactatactg agattatgga atttctcgaa
    27241 gagttacatc aaaaagggca taccattgtc atgattaccc atgatatgca attgatgctg
    27301 gattattcag accgggtcct tgtcatggtg gatggagaat tgattgccga tactgttcca
    27361 gccagtctgt tgagcgatcc tgagctgtta gtaaaagcca atctaaaaga aacctccatc
    27421 tttaacttgg ctaagaaact agatgtggat ccactggatt taacggcatt ttacaaagaa
    27481 aggagagagg gatgcaagct aaattaatcg gttaccagca tagagatact gtgattcatc
    27541 gcttgtcagg agctgggaaa cttctctttt tcattctggt atcattggcg gccatgatta
    27601 gctatgatac cagaatgctc ttgctgattg ccatcttttc agtctttctc ctctatttat
    27661 cagaaattcg ctttaaagat gtttcctttg tagccgtttt tgcgacggta tttgccgttt
    27721 taaacgtttt gatggtctat ctcttttctc ccgagtatgg ggttggactt tatggagaga
    27781 gaagtgtgat ttggcaggga atcggtgtct acactctaac cagccaggag ctcttttatc
    27841 tgctaaattt ggccattaag tatctttgca ccattcctct ggctattatc tttttgatga
    27901 caacccatcc tagtcagttt gcttccagtt taaatcaaat tggtgtgccc tataagattg
    27961 cttattctgt cagcctgacc ttgcgctata ttccagattt gcaggaagaa ttctttacta
    28021 tcaagatgtc tcaggaggcg cgtgggatgg aattatccaa gaaagcttct cttatgcaac
    28081 gaatcaaagg caatctgctc attattacgc ccttgatttt tagctcgcta gaacgcattg
    28141 ataccattgc gactgccatg gagcttcgcc gctttgggaa agagaaaaaa cgcacatggt
    28201 atagttatca ggccttgaaa aaaggagact atattacctt gctcttggca accttgtttt
    28261 tagtagttag tttactactt atcttgcaga atcagggacg attttacaac ccttggaaat
    28321 agcttgaaaa aattgaaaaa atcaagtcat ttctattgac aatgattctg aaagtgttat
    28381 actaagaaag tagtttcgct gatttacttc aaacctgttg tgaggtaagt taacgatgcc
    28441 ttaaccacgc tgtttgctga gcttgactcc gggcagtgtg gctatttttt tgcaatggtg
    28501 aaaggaagca agtcatgaca aatcacattg tattatttga acctcaaatt ccacaaaata
    28561 cgggcaatat cgcgcgtact tgcgctgcga ccaattctcc cctccacatc atcaagccta
    28621 tgggctttcc tattgatgac cgcaagatga agcgggctgg attggattac tgggataagc
    28681 tagagattta tttttacgag agtttggaag atttcatatc tcagatgaag ggaaaactct
    28741 atctgatttc gaaattcgcg gaaaaagtct attctgaggt ggatttatcg actgacgagg
    28801 accattattt tctctttgga cgtgaagaca agggcttacc tgaagatttt atgcgagaac
    28861 atcctgagaa ggctctccgt attcccatga atgatgaaca tgtccgcagt ctcaatgtgt
    28921 ctaataccgt ctgcatgatt gtctatgagg ctcttcgcca gcagaacttt gcaggtcttg
    28981 agctcgtcca tacctatgaa gtggataaat tgaaataaaa aatgaaaatg aacaaaatgc
    29041 ttgcgcttgc aagcgttttt tgttatgata aaagagtctt cagggcaggg tgtgattccc
    29101 gaccggcggt gactttaact aggaaatgat cttttccttt tatactttgt tgacaagctt
    29161 tgcctaacca gaagttatgc ctacagcttg tcgcctagtc taaaagaaaa atctctattt
    29221 ccttctcttt aaagaagtcc gcgagcgcaa gctgatgtgg tgagattcca caaccgacag
    29281 tatagtctgg atgggagaag acgaaagaat agctttgtct gttttgatag atttatagcc
    29341 ggattgtaac cacttgcttt gtttttcttt aatagagtaa gagggaactt ttgggatata
    29401 aaaagtgaga atagatagag gaatcctttc caacttcttc tgattttata gaaaattgga
    29461 ggaacctgtt atgacaaaca cacgtcgact ttcgaccatt gcaattttat cagccatctc
    29521 atttgtgctg atgtactttg actttccgct tttaccagcg gcatctttcc tcaagatcga
    29581 atttagtatc ttgccagtcc ttgtgggtct ggtggtcatg gatttgcctg ctgctctagg
    29641 agtgctcttg cttcgctcac tattgaaatt gcttcttaac agccaaggag tgaatactta
    29701 cattggtttg ccgatgaata tcgtagcttt gggagttttt gtcatcgtat ttgctttgat
    29761 ttggaaaaag gaacggacaa cccttcgttt cctactaggc tctctagctg gaactgttgg
    29821 tttaaccttg gccatgttgg ttctcaacta tgtttatgct gttcctttgt acgctaagtt
    29881 tgctaacttt gatattggaa aaattttggg actttccaac tacctaatga ccatggtatt
    29941 accttttaac ttgattgagg gtgtaatctt ttccgtttca ttctggttgt tgtacgtcct
    30001 tttgaaacca accttaaaac actatgaaag ataaacaaac atttttaatg aagggcagtt
    30061 ttgccctttt acttttcgtt attcttggct atatggtcaa attttaccct gaaatgttgg
    30121 tcaattttga ccaatcgatt cagactgcca ttcgaggaga cttaccagat tatttgacta
    30181 ttctttttcg atccctcaca cgtctgattg atatcccagt gattatcact tgggttgtca
    30241 ttacagcttt tgtcttttat cgtaagcgat ggaagataga aagtttcttc atgctgggaa
    30301 atctggcttt ggcaggtctt ttaatcgtga cctttaaaaa tatctaccag cgcccacgac
    30361 cagctatctt acatctggtg gaggagaagg gattttcctt cccaagtggg cattctctgg
    30421 ctgtaacctt gatggtaggt actttgattg ttattcttag tcagcggatt aaagagccag
    30481 tctggagaaa aatcgtacaa atcgtccttg gcctctacct agtcagtgtg ctggtatcaa
    30541 gagtctatct gggagttcat tacccatcag acgtccttgc cagtctctgt gtgggcttgg
    30601 gagtcctgtt tatcgagttt cccttctatg acaagctccg cttccaatgg cgatttaaag
    30661 gcaaacagaa gtgagtatcg aattcccttg aggagaaaga aatgaaagtc aatatagcag
    30721 atcttcatcc gactcaacta tatttatcag aaaagaagtt gcaagatatt cagatgcttt
    30781 accagtcggc agaaacaatc caagtcgatc caatcagtat tcttgccttt ggagattgtt
    30841 tgctgattac agatgggcat cacagggctt atcaggcttt attggcaggt cgggatacga
    30901 tttctgctga gtgggataga gatggtggtg atgaactata tcatctctat gcgcaagctt
    30961 gcgaggaaag aaagatttac tctgtttttg atttagaaga tcgtatccta gctcaagatg
    31021 ggtatgaagc aaaatggtat aactggtgtg atggttttaa tcaagcagca actcttttgt
    31081 tgaaaaggta gtgcattgtg ttttgttcct tattataagg tcaattattg tgaggaagct
    31141 tttgcttggt atcaggatgt gaacttggtt tacctcgtag atggggtgaa gcttccttac
    31201 agtcaagcga ccttggaagc catgtattcc tatttggatc ggcatggtga gcttttttgg
    31261 attgaagtca aggagaaggg agaatggttt ccaattgggg atattacact atctcaggat
    31321 aatctcccca ttgtgattgg gaattccgct taccaacatc gaggacttgg aaaaaagatt
    31381 ctaagtgctt tgattgaatt ggctcgagta aaaggatgga aagaattgag agtcaaggaa
    31441 atctacacct acaatcatgc ttctaggagg tgtttcaagt cgcttggatt tgtggaaaat
    31501 ggagcaacag aaaaaggaag gagttttata ttggaattag tctaatcctg ccactttctc
    31561 ccccttaacc tttgactatt ccgcaaaatt atcgtaaaat aaagagtaaa tgataaaatg
    31621 aggtcagagt ctgttcgctc tggcgatagt agtataaatg aggagaaacg ctttggaatt
    31681 agaagtattt gctgggcaag aaaaaagtga actatctatg attgaggtag cgcgtgctat
    31741 cttggaactt cgtggtcgcg atcatgagat gcattttagc gatcttgtaa acgaaattca
    31801 aaactacctt ggaacatcaa acagcgatat ccgcgaagct ttgcctttgt tctacacaga
    31861 gttgaacttt gacggtagct tcatctcact tggggacaac aaatggggtc ttcgttcatg
    31921 gtatggtgtg gacgaaatcg acgaagaaat catcgctctt gaagaaaatg acgacgatga
    31981 agtagcacca aaagctaaga aaaaacgtgt caatgccttt atggatggtg attcagatgc
    32041 cattgactac aatgcagatg atccagaaga cgaagatgca tacgaagcag atccagctct
    32101 ttcatacgat gatgaaaatc cagatgatga aaaaaatgaa gtggaagctt atgatgcaga
    32161 aatcaacgaa atcgctccag atgacttggg agaagatgtg gatctcaacg aagacgacga
    32221 cgagttttca gatgacgacg ctgaaaccag cgaggaataa gagttagcta ttgacaatta
    32281 tcctattttt aggtatcata ttgtttgggc acctctttta gaggtcgggg ctccctagtt
    32341 cttagggagc tatttttatt ttttcaagaa gttatcttct tgtattttat actcaatgaa
    32401 aatcaaagag caagctagga aactagccgt aggctgctca aaacactgtt ttgaggttgt
    32461 agataagact gacaaagtca ggaacacata tctacggcaa ggcgacgttg acgcggtttg
    32521 aagagatttt cgaagagtat tagttgtgaa tctggtgcag ttgtcccaga ttattcttat
    32581 tagtagggtc ttgttttcta tatcccctcg tagttaacaa gaccttgagc attttagaaa
    32641 gaggaatcta tgtctacgaa atatattttt gtaactggtg gtgtggtatc gtctattggg
    32701 aaagggattg tggcagcgag tctaggccgt ctcttgaaaa atcgtggtct caaagtaacc
    32761 attcaaaagt ttgaccctta tatcaatatt gatccgggaa ccatgagtcc ttaccagcac
    32821 ggggaagttt ttgtgacaga tgacggagct gagacagatt tggacttggg tcactatgaa
    32881 cgtttcatcg atatcaatct caacaaatat tccaacgtga caactgggaa aatttatagt
    32941 gaagttcttc gtaaagaacg ccgtggagaa taccttgggg caactgttca agtcattcct
    33001 catatcacag atgctttgaa agaaaaaatc aagcgtgccg ctctaacgac cgactctgat
    33061 gtcattatca cagaggttgg tggaacagta ggagatatcg agtccttgcc attcctagag
    33121 gctcttcgtc agatgaaggc agatgtgggt gcggataatg tcatgtatat ccatacaacc
    33181 ttgcttcctt acctcaaggc tgctggtgaa atgaaaacca aaccaaccca acactctgtc
    33241 aaagaattgc gtggcttggg aatccaacca aatatgttgg ttattcgtac agaagagcca
    33301 gctggtcaag gaattaaaaa taaactggcc cagttctgtg atgtggcacc agaagccgtt
    33361 atcgaatcgt tggatgttga acacctttac caaattccac tgaacttgca ggcacaaggg
    33421 atggaccaaa ttgtttgtga tcatttgaaa ttagacgcac cagcagcgga tatgacagaa
    33481 tggtcagcca tggtggacaa ggtcatgaac ctcaagaaac aagttaagat ttcccttgtt
    33541 ggtaagtatg tggagttgca agatgcctat atctcagtgg tcgaagcctt gaaacactct
    33601 ggctatgtca atgatgtaga agttaaaatc aattgggtca atgccaatga tgtgacagca
    33661 gagaatgtag cagaactctt gtctgatgcg gacgggatca tcgtaccagg tggttttggt
    33721 caacgtggaa cagaagggaa aatccaagcc atccgctatg cgcgtgaaaa tgatgttcca
    33781 atgttgggag tctgcttggg aatgcagttg acatgtatcg agtttgctcg tcacgtttta
    33841 ggtcttgaag gtgccaattc tgcagagctt gcaccagaaa caaaataccc tatcattgat
    33901 atcatgcgtg atcagattga tattgaggat atgggtggaa cccttcgttt gggactttat
    33961 ccgtctaagt tgaaacgtgg ctctaaggct gctgctgctt atcacaatca agaagtggtg
    34021 caacgccgtc accgtcaccg ttatgagttt aataatgcct tccgtgagca gtttgaggca
    34081 gcaggttttg tcttttcagg agtttctcca gacaatcgtt tggtagaaat cgtggaaatt
    34141 cctgaaaata aattctttgt agcttgtcag tatcaccctg aactgtcaag ccgtccaaac
    34201 cgaccagaag aactctacac tgcctttgtt actgcagcgg ttgagaacag caattagcaa
    34261 aatcagaacc tttgagaaaa atctcagagg ttttttgcat acgatgatat tgcagtatat
    34321 ctgaggtagg ggtcctctgt atgtacctgc taccgttgaa atcaatagcg actccctctt
    34381 gccctgtgct agtgaatgga tttatcagta tattgaaatg aaataaaatt tgaacaaatt
    34441 aattcggaaa gccaaatcaa tttctagcaa agttttagga actggattgt at
//
LOCUS       DAVKZI010000021        34414 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKZI010000021 DAVKZI010000000
VERSION     DAVKZI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.021"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            566..1018
                     /locus_tag="VXB18_001183"
     CDS             566..1018
                     /locus_tag="VXB18_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0382391.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1037..2374
                     /locus_tag="VXB18_001184"
     CDS             1037..2374
                     /locus_tag="VXB18_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0382392.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLGSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2453..3337
                     /locus_tag="VXB18_001185"
     CDS             2453..3337
                     /locus_tag="VXB18_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0382393.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3337..4170
                     /locus_tag="VXB18_001186"
     CDS             3337..4170
                     /locus_tag="VXB18_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0382394.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4188..6281
                     /gene="nanB"
                     /locus_tag="VXB18_001187"
     CDS             4188..6281
                     /gene="nanB"
                     /locus_tag="VXB18_001187"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0382395.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVREKGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6293..7396
                     /locus_tag="VXB18_001188"
     CDS             6293..7396
                     /locus_tag="VXB18_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0382396.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7570..8268
                     /locus_tag="VXB18_001189"
     CDS             7570..8268
                     /locus_tag="VXB18_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0382397.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8287..9804
                     /locus_tag="VXB18_001190"
     CDS             8287..9804
                     /locus_tag="VXB18_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0382398.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9929..11257
                     /locus_tag="VXB18_001191"
     CDS             9929..11257
                     /locus_tag="VXB18_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0382399.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11509..12375
                     /locus_tag="VXB18_001192"
     CDS             11509..12375
                     /locus_tag="VXB18_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0382400.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12391..13230
                     /locus_tag="VXB18_001193"
     CDS             12391..13230
                     /locus_tag="VXB18_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0382401.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13502..13954
                     /locus_tag="VXB18_001194"
     CDS             13502..13954
                     /locus_tag="VXB18_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0382402.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYASMEEKVRKYLFKILID"
     gene            14096..14404
                     /locus_tag="VXB18_001195"
     CDS             14096..14404
                     /locus_tag="VXB18_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382403.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGTYAAKYGISMARSI
                     LNRAAATAAERVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDAHDKIPNNGRINF
                     "
     gene            14691..15335
                     /locus_tag="VXB18_001196"
     CDS             14691..15335
                     /locus_tag="VXB18_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0382404.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15504..16421
                     /locus_tag="VXB18_001197"
     CDS             15504..16421
                     /locus_tag="VXB18_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0382405.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16439..17323
                     /locus_tag="VXB18_001198"
     CDS             16439..17323
                     /locus_tag="VXB18_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0382406.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17339..18190)
                     /locus_tag="VXB18_001199"
     CDS             complement(17339..18190)
                     /locus_tag="VXB18_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0382407.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18390..20447
                     /gene="pbp2b"
                     /locus_tag="VXB18_001200"
     CDS             18390..20447
                     /gene="pbp2b"
                     /locus_tag="VXB18_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0382408.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20458..21054
                     /gene="recR"
                     /locus_tag="VXB18_001201"
     CDS             20458..21054
                     /gene="recR"
                     /locus_tag="VXB18_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0382409.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21230..22273
                     /locus_tag="VXB18_001202"
     CDS             21230..22273
                     /locus_tag="VXB18_001202"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0382410.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22357..23730
                     /locus_tag="VXB18_001203"
     CDS             22357..23730
                     /locus_tag="VXB18_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0382411.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLAAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23717..24328
                     /locus_tag="VXB18_001204"
     CDS             23717..24328
                     /locus_tag="VXB18_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0382412.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24419..25123
                     /locus_tag="VXB18_001205"
     CDS             24419..25123
                     /locus_tag="VXB18_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0382413.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25342..26715
                     /gene="ftsA"
                     /locus_tag="VXB18_001206"
     CDS             25342..26715
                     /gene="ftsA"
                     /locus_tag="VXB18_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0382414.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26732..27991
                     /gene="ftsZ"
                     /locus_tag="VXB18_001207"
     CDS             26732..27991
                     /gene="ftsZ"
                     /locus_tag="VXB18_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0382415.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27996..28667
                     /locus_tag="VXB18_001208"
     CDS             27996..28667
                     /locus_tag="VXB18_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0382416.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28677..29216
                     /locus_tag="VXB18_001209"
     CDS             28677..29216
                     /locus_tag="VXB18_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0382417.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29216..29479
                     /locus_tag="VXB18_001210"
     CDS             29216..29479
                     /locus_tag="VXB18_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0382418.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29476..30261
                     /locus_tag="VXB18_001211"
     CDS             29476..30261
                     /locus_tag="VXB18_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0382419.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVFSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30270..31058
                     /gene="divIVA"
                     /locus_tag="VXB18_001212"
     CDS             30270..31058
                     /gene="divIVA"
                     /locus_tag="VXB18_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0382420.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31406..34198
                     /locus_tag="VXB18_001213"
     CDS             31406..34198
                     /locus_tag="VXB18_001213"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0382421.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     LRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10575 a         6064 c         7491 g        10284 t
ORIGIN      
        1 aacggtaaca aaactaattt agagaatgaa atatagagta tttctctctt aaaagttttt
       61 ggtgaaacga gatgtagaaa ggagatttag ccaaagagtc tattagtgct agaataatag
      121 attagaatta ttttagaaaa acgaagtgag cagcttataa attcaagtcc ccaaatagat
      181 tcatactagt atcttttgca aaaaataaag ggcgacttcc ttcatgaata tcaatttcat
      241 ctataaggaa ggtagctaat tgaactaact tatttattct gtttgtcgct agaaaaatca
      301 gacctccttg tgaagattga ggagatactg aatgaaaatc aaagaagaaa ctagcaagct
      361 agtagcagat tgcccaaaac accgctttga ggttgtagat aagactgacg tatataatcc
      421 aaggtgaagc gactgtggtt tgaagagatt ttcaaagagt ataggctaga gagtagtgtt
      481 tttatgtcct tctagtagaa aatgctagac agaagaatgg ggaacttgga taggaaaaat
      541 agattgagaa aggaggttag aagagatgat tattacaaaa attagccgtt taggaactta
      601 tgtgggagta aatccacatt ttgcaacatt aatagatttt ctagaaaaaa caggactaga
      661 aaatttaaca gaaggttcga ttgctatcga tggtaatcga ttgtttggga attgctttac
      721 ttatctagca gatggtcaag caggggcttt ctttgaaaca caccaaaaat atttggatat
      781 tcatttagtt ttggaaaacg aagaagccat ggctgttaca tcgccggaaa atgtaagcgt
      841 tacccaagaa tatgatgaag agaaagatat tgaattatac acagggaaag tggaacagtt
      901 ggttcatttg agagctggcg aatgcctcat cacttttcca gaagatttac atcaacccaa
      961 ggttcgtata aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga tttcttaatg
     1021 tagaaagaga agaacgatga aaaaaatgag aaagttttta tgtctagctg gaattgcgct
     1081 agcggctgtt gccttggtag cttgttcagg aaaaaaagaa gctacaacta gtactgaacc
     1141 accaacagaa ttatctggtg agattacaat gtggcactcc tttactcaag gaccccgttt
     1201 agaaagtatt caaaaatcag cagatgcttt catgcaaaag catccaaaaa cgaaaatcaa
     1261 gattgaaaca ttttcttgga atgacttcta tactaaatgg actacaggtt tagcaaatgg
     1321 aaatgtgcca gatatcagta cagctcttcc taaccaagta atggaaatgg tcaactcaga
     1381 tgctttggtt ccgctaaatg attctatcaa gcgtattgga caagataaat ttaacgaaac
     1441 tgccttaaat gaagcaaaaa tcggagatga ttactactct gttcctcttt attcacatgc
     1501 acaagtcatg tgggttagaa cagatttgtt aaaagaacat aatattgagg ttcctaaaac
     1561 ttgggatcaa ctctatgaag cttctaaaaa attgaaagaa gctggagttt atggcttgtc
     1621 tgttccgttt ggaacaaatg acttaatggc aacacgtttc ttgaacttct acgtacgtag
     1681 tggtggagga agcctcttaa caaaagatct taaagcagac ttgacaagcc aacttgctca
     1741 agatggtatt aaatactggg ttaaattgta taaagaaatc tcacctcaag attctttgaa
     1801 ctttaatgtc cttcaacaag ctaccttgtt ctatcaagga aaaacagcat ttgactttaa
     1861 ctctggcttc catatcggag gaattaatgc caacagtcct caattgattg attcgattga
     1921 tgcttatcct attccaaaaa tcaaagagtc tgataaagac caaggaattg aaacctcaaa
     1981 cattccaatg gttgtttgga aaaattcaaa acatccagaa gttgctaaag cattcttaga
     2041 agcactttat aatgaagaag actacgttaa attccttggt tcaactccag taggtatgtt
     2101 gccaactatt aaggggatta gcgattctgc agcctataaa gaaaatgaaa ctcgtaagaa
     2161 atttaaacat gctgaagaag taattactga agctgttaaa aaaggtactg ctattggtta
     2221 tgaaaatgga ccaagtgtac aagctggtat gttaactaac caacacatta ttgaacaaat
     2281 gttccaagat atcattacaa atggaacaga tcctatgaaa gcagcaaaag aagcagaaaa
     2341 acaattaaac gatttatttg aggctgttca gtagatgtaa aagactagaa aataggtggg
     2401 ctagtgatct gaaaagctct agcccaatct tgtaaaagaa gggagaagga gaatggttaa
     2461 agaacgtaat ttaactcgct ggatatttgt tttgccagct atgattatcg taggattact
     2521 ctttgtttat ccgtttttct cgagtatttt ttatagcttt accaataagc atttgattat
     2581 gcctaattat aaatttgttg gtttggctaa ctataaagct gtgctatcag atcccaactt
     2641 ctttaatgcg ttctttaatt caattaagtg gaccgttttc tcattagttg gtcaagtttt
     2701 agtagggttt gtattggctt tagctcttca cagagtacgc cacttcaaga aattatatag
     2761 gaccttattg attgttcctt gggcatttcc taccatcgtt attgcctttt cttggcagtg
     2821 gattctaaac ggggtttatg gctacttacc taatctaatc gtaaaattag gtttaatgga
     2881 acatacacct gcatttttga cagatagtac atgggcattc ctatgtttgg tgtttatcaa
     2941 catttggttt ggagcaccaa tgattatggt taatgtgctt tcagctttgc aaacagtacc
     3001 agaagaacaa tttgaggctg ctaagataga tggtgcttca agttggcagg tgttcaagtt
     3061 tatcgtcttt ccacatatta aagtggttgt aggacttcta gttgttttga gaactgtatg
     3121 gatctttaat aactttgaca ttatctacct cattactggt ggtggaccag ccaatgctac
     3181 aacgacgctt ccaatttttg cttacaacct gggctgggga actaaattgt tgggtcgtgc
     3241 ttcagcagtt acagtattgc tctttatctt cttggtggcg atttgcttta tctactttgc
     3301 tatcatcagt aagtgggaaa aggagggtag aaaataatga agaagaaatc cagtatttat
     3361 ttagatattc tctcacatgt acttttagtt ggtgcgacca tcgttgcagt tttcccattg
     3421 gtatggatta tcatatcttc tgtcaaaggg aaaggggaat taactcagta tccaacacga
     3481 ttttggcctg aacagtttac attagattat ttcactcatg ttatcaacga tttgcacttc
     3541 attgataaca ttcgaaacag tttaatcatt gccttggcta caacccttat tgcgattatt
     3601 atttctgcta tggcagccta tggtattgtt cgattctttc ctaaattggg agcaatcatg
     3661 tcgagactac tcgtcattac ctacattttc ccaccaattt tgttagcaat tccctattca
     3721 attgccattg ctaaagttgg gttaacaaat agtttatttg gcttgatgat ggtttatcta
     3781 tcttttagtg ttccatatgc agtttggctc ttagttggat ttttccaaac agttccaatt
     3841 ggaattgaag aagcggctag aattgatggt gcaaataaat ttgttacgtt ttataaagtt
     3901 gtgctaccga ttgtagcacc aggtattgta gcaacagcta tttatacatt tatcaatgct
     3961 tggaatgaat tcctgtatgc cttgattttg attaacaata caggaaagat gacagtagca
     4021 gtagcccttc gttcacttaa tggttcagaa atactagact ggggagatat gatggcagcg
     4081 tctgttattg tagttcttcc atcaattatt ttcttctcta tcatccaaaa taagattgca
     4141 agtggattat cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg aataaaagag
     4201 gtctttattc aaaactagga atttctgttg taggcattag tcttttaatg ggagtcccca
     4261 ctttgattca tgcgaatgaa ttaaactatg gtcaactgtc catatctcct atttttcaag
     4321 gaggttcata tcaactgaac aataagagta tagatatcag ccctttgtta ttagataaat
     4381 tgtctggaga gagtcagaca gtagtaatga aatttaaagc agataaacca aactctcttc
     4441 aagctttgtt tggcctatct aatagtaaag caggctttaa aaataattac ttttcaattt
     4501 tcatgagaga ttctggtgag ataggtgtag aaataagaga cgcccaaaag ggaataaatt
     4561 atttattttc tagaccagct tcattatggg gaaagcataa aggacaggca gttgaaaata
     4621 cactagtatt tgtatctgat tctaaagata aaacatacac aatgtatgtt aatggaatag
     4681 aagtgttctc tgaaacagtt gatacatttt tgccaatttc aaatataaat ggtatagata
     4741 aggcaacact aggagctgtt aatcgtgaag gtaaggaaca ttacctcgca aaaggaagta
     4801 ttggtgaaat cagtctattt aacaaagcaa ttagtgatca ggaagtttca aatattccct
     4861 tgtcaaatcc atttcagtta attttccaat caggagattc tactcaagct aactatttta
     4921 gaataccgac actatataca ttaagtagtg gaagagttct atcaagtatt gatgcacgtt
     4981 atggtgggac tcatgattct aaaagtaaga ttaatattgc cacttcttat agtgatgata
     5041 atgggaaaac gtggagtgag ccaatttttg ctatgaagtt taatgactat gaggagcagt
     5101 tagtttactg gccacgagat aataaattaa agaatagtca aattagtgga agtgcttcat
     5161 tcatagattc atccattgtt gaagataaaa aatctgggaa aacgatatta ctagctgatg
     5221 ttatgcctgc gggtattgga aataataatg caaataaagc cgactcaggt tttaaagaaa
     5281 taaatggtca ttattattta aaactaaaga agaatggaga taacgatttc cgttatacag
     5341 ttagagaaaa gggtgtcgtt tatgatgaaa caactaataa acctacaaat tatactataa
     5401 atgataagta tgaagttttg gagggaggaa agtctttaac agtcgaacaa tattcggttg
     5461 attttgatag tggctcttta agagaaaggc ataatggaaa acaggttcct atgaatgttt
     5521 tctacaaaga ttcgttattt aaagtgactc ctactaatta tatagcaatg acaactagtc
     5581 agaatagagg agagagttgg gaacaattta agttgttgcc tccgttctta ggagaaaaac
     5641 ataatggaac ttacttatgt cccggacaag gtttagcatt aaaatcaagt aacagattga
     5701 tttttgcaac atatactagt ggagaactaa cctatctcat ttctgatgat agtggtcaaa
     5761 catggaagaa atcctcagct tcaattccgt ttgaaaatgc aacagcagaa gcacaaatgg
     5821 ttgaactgag agatggtgtg attagaacat tctttagaac cactacaggt aagatagctt
     5881 atatgactag tagagattct ggagaaacat ggtcgaaagt ttcgtatatt gatggaattc
     5941 aacaaacttc atatggcaca caagtatctg caattaaata ctctcaatta attgatggaa
     6001 aagaagcagt cattttgagt acaccaaatt ctagaagtgg ccgtaaggga ggccaattag
     6061 ttgtcggttt ggtcaataaa gaagatgata gtattgattg gagataccac tatgatattg
     6121 atttgccttc gtatggttat gcctattctg cgattacaga attgccaaat catcacatag
     6181 gtgtactgtt tgaaaaatat gattcgtggt cgagaaatga attgcattta agcaatgtag
     6241 ttcagtatat agatttggaa attaatgatt taacaaaata aaggagaaaa acatggttaa
     6301 atacggtgtt gttggaacag ggtattttgg agctgaattg gctcgctaca tgcaaaagaa
     6361 tgatggagca gagattactc ttctctatga tccagataat gcagaggcga ttgcagaaga
     6421 attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg aagtagattg
     6481 tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg ctgcacagca
     6541 tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt gtcgcgagat
     6601 ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta tgaatttctt
     6661 taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag acgttctata
     6721 ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat ggaaaaaaat
     6781 tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt gcgttcaatt
     6841 ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg cccatgaagg
     6901 tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt ctaataagcg
     6961 ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg tcttaatcca
     7021 aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc ttaagctaga
     7081 tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg atcggactcg
     7141 tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag gtaaacgtac
     7201 tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg agattatgga
     7261 aggagctcca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg ccctagaagc
     7321 aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag taaaattgtc
     7381 agaaattgta aaataaattt tggtattctc ctatttatag gtcgacttgc tcctctgaaa
     7441 gtacttttag aggagctgtt tgactttgct agtttttgaa actgaaatct attatactac
     7501 aaactattga aagcgtttta attttaaggt ataataatct catagaaata aagaaaagga
     7561 ggaaagagga tgccacagat tagcaaagaa gccttgattg agcaaatcaa agatggaatc
     7621 atcgtttctt gtcaggctct tcctcatgaa ccgctttata cagaagcggg aggggtgatt
     7681 cccttgctgg tcaaagcggc tgagcaaggt ggagcagtcg gtatccgagc aaacagtgtt
     7741 cgcgatatca aggaaattaa ggaagtcact aaacttccaa tcattgggat tatcaaacgt
     7801 gattatccac ctcaggaacc cttcatcacg gctactatga aagaagttga tgaattggca
     7861 gaactggaca tcgaggtgat tgctctggat tgtaccaagc gtgaacgcta cgatggtttg
     7921 gaaattcaag agttcattcg tcaggttaag gagaaatatc ctaatcagct tttgatggct
     7981 gatactagta tcttcgaaga agggctagca gctgtagaag caggaattga ctttgtcgga
     8041 acaaccttat caggctacac atcctacagt ccaaaagtag acggtccaga ttttgaattg
     8101 attaagaaac tctgtgatgc tggtgtagat gtcattgcag aaggaaaaat tcatacacca
     8161 gaacaagcca aacaaatcct tgaatatgga gtgcgaggca tcgttgttgg tggcgccatt
     8221 actagaccaa aagagattac agaacgcttc gttgctagtc ttaaataaga tgtgaggggg
     8281 agttttatgt ttaaagtttt acaaaaagtt ggaaaagctt ttatgttacc tatagctata
     8341 cttcctgcag caggtctact tttggggatt ggtggtgcac tttcaaaccc aaccacgata
     8401 gcaacttatc caatactaga caatagtatt tttcaatcaa tattccaagt aatgagctct
     8461 gcaggagagg ttgtattcag taatttgtca ctacttctct gtgtgggatt atgtattggc
     8521 ttagcgaaac gagataaagg aaccgctgcg ttagcaggag taactggtta cttagttatg
     8581 actgcaacga tcaaagcttt ggtaaaactt tttatggcag aaggatctgc aattgatact
     8641 ggagttattg gagcattagt tgtcggaata gttgccgtat atttgcacaa ccgatataac
     8701 aatattcaat taccttccgc tttaggattc tttggaggtt cacgcttcgt tcctattgtt
     8761 acatcgttct cttctatctt gattggcttt gtcttctttg ttatttggcc acctttccaa
     8821 caacttcttg tttctacagg tggatatatt tctcaggcgg gtccaattgg aacttttcta
     8881 tatggatttt taatgagact ttctggagca gtaggcttac atcatataat ttaccctatg
     8941 ttttggtata ctgaacttgg tggtgttgaa actgttgcag gacaaacagt ggttggagct
     9001 caaaaaatat tttttgctca attagccgat ttggcccatt ctggattatt tacagaagga
     9061 acaaggtttt ttgcaggtcg tttctcaaca atgatgttcg gtttaccggc tgcctgttta
     9121 gcgatgtacc atagtgttcc taaaaatcgt cgtaaaaaat acgcgggttt gttttttgga
     9181 gttgctttaa catcttttat taccggtatt acagaaccaa ttgaatttat gtttctattc
     9241 gtcagtccgg ttctatatgt tgttcacgca ttccttgatg gtgttagctt ctttattgca
     9301 gacgtcttaa atatttcaat aggaaacaca ttttcaggag gtgtaatcga tttcacttta
     9361 tttggaattt tgcaggggaa cgctaagacg aattgggttc ttcagattcc atttggactt
     9421 atttggagtg ttttgtatta tattattttt agatggttca ttactcaatt caacgttcta
     9481 acgccagggc gaggagaaga agtagattct aaagaaattt ctgaatccgc agattcaact
     9541 tcaaatactg cagattattt aaaacaggat agcctacaaa ttatcagagc cttgggtgga
     9601 tcaaataata tagaagatgt agatgcttgt gtgacacgtt tacgtgtagc tgtaaaagaa
     9661 gttaatcaag ttgataaagc acttttaaaa caaattggtg cagttgatgt cttagaagtg
     9721 aagggtggca ttcaagcaat ctatggagca aaagcaatct tatataaaaa tagtattaat
     9781 gaaattttag gtgtagatga ttaagtactt actgacttaa taaaaaacag aggagagtga
     9841 tggatgagta ggatgaaatg aaatcgcata caagaaataa agaactcatt atccaagttg
     9901 gatacgctta ttacatagga gaatacaaat gaaatttaga aaattagctt gtacagtact
     9961 tgcgggtgct gcggttcttg gtcttgctgc ttgtggcaat tctggcggaa gtaaagatgc
    10021 tgccaaatca ggtggtgacg gtgccaaaac agaaatcact tggtgggcat tcccagtatt
    10081 tacccaagaa aaaactggtg acggtgttgg aacttatgaa aaatcaatca tcgaagcgtt
    10141 tgaaaaagca aacccagata taaaagtgaa attggaaacc atcgacttca agtcaggtcc
    10201 tgaaaaaatc acaacagcca tcgaagcagg aacagctcca gacgtactct ttgatgcacc
    10261 aggacgtatc atccaatacg gtaaaaacgg taaattggct gagttgaatg acctcttcac
    10321 agatgaattt gttaaagatg tcaacaatga aaacatcgta caagcaagta aagctggaga
    10381 caaggcttat atgtatccga ttagttctgc cccattctac atggcaatga acaagaaaat
    10441 gttagaagat gctggagtag caaaccttgt aaaagaaggt tggacaactg atgattttga
    10501 aaaagtattg aaagcactta aagacaaggg ttacacacca ggttcattgt tcagttctgg
    10561 tcaaggggga gaccaaggaa cacgtgcctt tatctctaac ctttatagcg gttctgtaac
    10621 agatgaaaaa gttagcaaat atacaactga tgatcctaaa ttcgtcaaag gtcttgaaaa
    10681 agcaactagc tggattaaag acaatttgat caataatggt tcacaatttg acggtggggc
    10741 agatatccaa aactttgcca acggtcaaac atcttacaca atcctttggg caccagctca
    10801 aaatggtatc caagctaaac ttttagaagc aagtaaggta gaagtggtag aagtaccatt
    10861 cccatcagac gaaggtaagc cagctcttga gtaccttgta aacgggtttg cagtattcaa
    10921 caataaagac gacaagaaag tcgctgcatc taagaaattc atccagttta tcgcagatga
    10981 caaggagtgg ggacctaaag acgtagttcg tacaggtgct ttcccagtcc gtacttcatt
    11041 tggaaaactt tatgaagaca aacgcatgga aacaatcagc ggctggactc aatactactc
    11101 accatactac aacactattg atggatttgc tgaaatgaga acactttggt tcccaatgtt
    11161 gcaatctgta tcaaatggtg acgaaaaacc agcagatgct ttgaaagcct tcactgaaaa
    11221 agcgaacgaa acaatcaaaa aagctatgaa acaatagtcc ttagttattc tataaaaagt
    11281 agttttttaa agaacctaag agtgtatacc cccttttccc tctacacaga tagtgtaaga
    11341 aaagggggct tttgtttaaa atgtaagaaa ctgtcacgaa attaaaatga agttcttaca
    11401 taagcgaatc ataaaaaatt tcattttgat tttaaaacag ttcaagaaag tcaaaaaatt
    11461 attctatttg aaagagaggt gccgactgtg aaagtcaata aaatccgtat gcgggaaaca
    11521 gtgatttcct acgctttcct agcaccagta ttattcttct ttgtcatctt tgtgttggct
    11581 ccgatggtga tgggcttcat tacaagtttc tttaactact caatgactaa atttgagttt
    11641 gtaggcttgg ataactatat ccgtatgttt aaagatcctg tctttacaaa atctctgatt
    11701 aacacagtta ttttggttat tggatctgta ccagttgttg ttctattctc actctttgta
    11761 gcatctcaga cctatcatca aaatgtcatt gccagatcct tctaccgttt cgtcttcttc
    11821 cttcctgttg taacgggtag tgttgccgtg acagttgttt ggaaatggat ttatgaccca
    11881 ctatcaggga ttctaaactt tgtccttaag tccagccaca tcatcagcca aaacatttct
    11941 tggttgggag ataaaaactg ggcattgatg gcgattatga ttattctctt gaccacttca
    12001 gttggtcagc ccatcatcct ttatatcgct gccatgggga atattgacaa ttcactggtt
    12061 gaagcggcgc gtgttgatgg tgcaactgag tttcaagttt tttggaagat taaatggcca
    12121 agccttcttc caacaactct ttatattgca atcatcacaa caattaactc attccagtgt
    12181 ttcgccttga ttcagctttt gacatctggt ggtccaaact actcaacaag taccttgatg
    12241 tactaccttt acgaaaaagc cttccaattg acagaatacg gctatgccaa cacaattggt
    12301 gtcttcttgg cagtcatgat tgctatcgta agctttgttc aatttaaagt acttggaaac
    12361 gacgtagaat actaaagaaa ggagacagct atgcaatcta cagaaaaaaa accattaaca
    12421 gcctttactg ttatttcaac aatcattttg ctcttgttga ctgtgctgtt catctttcca
    12481 ttctactgga ttttgacagg ggcattcaaa tcacaacctg atacaattgt tattcctcct
    12541 cagtggttcc ctaaaatgcc aaccatggaa aacttccaac aactcatggt gcagaaccct
    12601 gccttgcaat ggatgtggaa ctcagtattt atctcattgg taaccatgtt cttagtttgt
    12661 gcaacctcat ctctagcagg ttatgtattg gctaaaaaac gtttctatgg tcaacgcatt
    12721 ctatttgcta tctttatcgc tgctatggcg cttccaaaac aagttgtcct tgtaccattg
    12781 gtacgtatcg tcaacttcat gggaatccac gatactctct gggcagttat cttgcctttg
    12841 attggatggc cattcggtgt cttcctcatg aaacaattta gtgaaaatat tcctacagag
    12901 ttgcttgaat cagctaaaat cgacggttgt ggtgagattc gtaccttctg gagtgtagcc
    12961 ttcccgattg tgaaaccagg gtttgcagcc cttgcaatct ttaccttcat caatacttgg
    13021 aatgactact tcatgcaatt ggtaatgttg acttcacgta acaatttgac catctcactt
    13081 ggggttgcga ccatgcaggc tgaaatggca accaactatg gtttgattat ggcaggagct
    13141 gcccttgctg ctgttccaat cgtcacagtc ttccttgtct tccaaaaatc cttcacacag
    13201 ggtattacta tgggagcggt caaaggataa tactctgcga aaatctcttc aaactacgtc
    13261 agcttcacct tgccatactt aagtattgcc tgcggttagc ttcctagttt gttcttcaat
    13321 tttcattgag tataggaaaa tcaatctatc aagatacaga agtatatttt atagatttag
    13381 agaatataga ggttataagt gtctacaaaa tggagggtat gcagttactt tatgaagttt
    13441 tgtcagacac ttataaactt aagaatggtt ttagttaact atcagaaacg aaggaaagag
    13501 tatgattttt gacgatttga aaaacatcac cttttacaaa gggattcatc ccaatttaga
    13561 caaggctatc gactacctct accaacatcg taaagattca ttcgaattag gaaagtatga
    13621 gattgatggg gataaagtct ttctagttgt tcaggaaaat gtcctcaatc aagttgagaa
    13681 taatcaattt gaacaccata agaactatgc agatttgcat ttgctgatag aagggcatga
    13741 atattcgagc tacggttcac gtatcaaaga cgaggcagta gcattcgacg aagcgactga
    13801 cattggcttt gttcattgtc atgaacacta ccccctcttg ttgggttatc acaattttgc
    13861 gattttcttc ccaggtgagc cacatcagcc aaatggttat gcaagcatgg aagaaaaggt
    13921 tcggaaatat ctctttaaaa ttttgattga ttaaaaatag gatgaattgt ttttttgtaa
    13981 agctttgaca atactctacc atgaaattga tctttgtgag gtagggaaat gagaataaaa
    14041 tatttaaaaa ttggtatctt cttgtcagtc tgtgtatgct acaagagcta gtttcttgga
    14101 tggacaggga attacagttg atgagatggc ttggataatt aggggcattg tgaatgcatt
    14161 gattggtaga tacataaaat taggtactta tgcggctaag tatggtatta gtatggcgcg
    14221 ttctatctta aatagagcag ctgcaactgc ggcagaaaga gtaggattat tgactaagat
    14281 ttttggatgg attttacgaa tagctgtgct cgcagctgat gtatatggta attttgccaa
    14341 caatattgct gtagcttggg atgcacatga taaaatccct aacaatggtc gtataaactt
    14401 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
    14461 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtaatat
    14521 tttagctagt gcgttgtcct cgctatacat acattatata tccatagata gaaaaagaaa
    14581 aaagtccaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta tgaaagcttt
    14641 actaacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagtaaac atggcacaaa
    14701 aaggagtaag ccttatcaag gcagcatttg atacagataa ctttcttatg cgttttagtg
    14761 agaaagtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt ttgcccatcg
    14821 tgacgattgg agtggctaaa atcagcctct acgagaccat gtttgagatt aagaagagca
    14881 gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg aaactaggtc
    14941 ttcagttagg tctgcttgag ttgggcattg tttcattaag cctcctagat ctttatctct
    15001 tttggggtca aacagctctg ccctttcaat tgctgaaagc tatttgtcta ggcattctga
    15061 ttttccttac gattgtgatg ttggctagct atccaatcgc ggcacgttat gatttaactt
    15121 ggaaagaagt gttacaaaaa gggcttatct tggcaagttt taactttcct tggttcttcc
    15181 tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtctgcc ttcagtctac
    15241 ttttaggtgg ctcagtcttc ctgctttttg ggtttggact attggttttt atccagactg
    15301 gattgatgga gaaaattttc gcaaaatacc aataggagcc ttatttctga aactactttc
    15361 aaaggctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct ataagatatt
    15421 gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct ttagcagaaa
    15481 ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt gtcattccag
    15541 ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg cgtgccttgg
    15601 ttcaatactt cattgataaa ggtgttcaag gtctttatgt caatggttct tctggtgaat
    15661 gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg gcggtagcca
    15721 aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagat agtatggaac
    15781 ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca ccaatttatt
    15841 tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct gcagctccaa
    15901 acacagacta cgtgatttac aacattcctc aattggcagg ggttgctttg actccaagcc
    15961 tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct tctatgccag
    16021 ttcaagatat ccaaaccttt gtgagccttg gtggggaaga ccatatcgtc tttaacggtc
    16081 cagatgaaca gttcctaggt ggtcgcctca tgggtgccaa agctggtatc ggtggtactt
    16141 atggtgctat gccagaactc ttcttgaaac tcaaccaatt gattgcggat aaggacctag
    16201 aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc acttctgctc
    16261 atggaaatat gtacggtgtc attaaagaag tcttgaaaat caatgaaggc ttgaatattg
    16321 gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt gtagaagcgg
    16381 ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atctaaaagg aggtatttat
    16441 gacatactac gttgcaattg atatcggtgg aaccaacatc aagtatggtt tggttgatca
    16501 agaggggcaa cttcttgaat cgcatgaaat gccaactgag gcgcataagg gtggacctca
    16561 tatcttacaa aagaccaaag atatcgtagc tagttattta gaaaaaggcc cagtagcagg
    16621 tgttgccata tcttctgctg ggatggtgga tccggataag ggtgagattt tctatgctgg
    16681 gcctcaaatc cctaactacg caggcaccca gttcaaaaag gaaatcgaag aaagctttac
    16741 tattccttgt gagattgaaa atgatgtcaa ctgtgcaggt cttgctgagg cagtatctgg
    16801 ttcaggcaag ggagcaagtg tgacactttg cttgaccatt ggaaccggta tcggtggttg
    16861 cttgattatg gataggaaag tcttccatgg ttttagcaat tcagcctgtg aagtcgggta
    16921 tatgcatatg caggatggag cttttcagga tctcgcttct acaacagctt tagtgaaata
    16981 tgtagctgaa gcccatggag aagatgttga tcagtggaat ggccgacgta tctttaagga
    17041 agctactgaa ggaaacaaaa tctgcatgga aggtattgac cgtatggttg actatctagg
    17101 aaaaggtctg gcaaatattt gttatgtggc caatccagaa gtagttattc ttggtggtgg
    17161 tatcatgggg caagaggcta tcctcaaacc taagatccgc acagccttga aagaggcatt
    17221 ggtaccaagt ttagcagaaa aaacacgatt agaatttgcc catcaccaaa atacagcagg
    17281 gatgttgggt gcatattatc attttaagac aaaacaatcc tagtttggct cagccaaact
    17341 aggattttct tacacgtttt tgtctacgat agccgttgag ttttttattt tcccagtagc
    17401 tattaaagat tttttccttg ctttcgcgat tgatttccaa aaagtaggca taaatcaaat
    17461 cgataaagaa gagcatagga agttgagcgg atattcgttg gatgtaggag ggttggctgt
    17521 gggtggctac aagaacagtc tctgtatagg tctggctatc tttattggga acacttgtaa
    17581 agagtacagt ctttgccccc atctccttgg catctaatag actatctaaa atagaaggag
    17641 ttgagcctga aagtgagaaa cccagtacta gacaattttc atccatgatg ctggttgtcc
    17701 aggcaaagcc gtcttggtct gtcaaagctt cgcagaccac acctagtcgc ataaaacgta
    17761 atttcatttc acgggcgacg aggccagaac tccctgttcc aaagaagtag atacgctcag
    17821 catcttcgat tagctgggca attcgctcta gttggatttc gtcaatcaag tcttgtgttt
    17881 gttccctcat attgctataa cttctgagga ctcgtttggt cagtggacta tgcttggaga
    17941 cttggttggc ttgattttct gcctgatgtt ggtattggaa aataaattct cggtagccag
    18001 taaagccaca ctttttagca aagcgggtca aagcagcttg agaaatatgt aatttttggg
    18061 tgacttgttg agaagataaa tcatctgtaa tcgtttcagc ttgcaaaaaa tagcgagcga
    18121 tttcttgctc taggtctgtc atttcttcaa aatgtgaatc aatgatagtt gcgatatctg
    18181 gtttgtccat agggaaagct cctttacatg ggtcatactg gaagactaga tcagggaata
    18241 gtcacacttc attataacac ataatataag gatagataaa taaaaacgca tttctgtttt
    18301 aaaaacgaaa aaatcgaaaa agcttctttc ttttccataa ttttctactc aaattgtggt
    18361 acaattaaga gtaagatttt aagttagaaa tgagactgat ttgtatgaga aaatttaaca
    18421 gccattcgat tccgattcgg cttaatttat tgttttcaat cgtcatttta ctctttatga
    18481 ccattattgg tcgtttgttg tatatgcagg ttttgaacaa ggatttttac gaaaaaaagc
    18541 tagcctcagc tagtcagacc aagattacaa gcagttcagc ccgtggggaa atttatgatg
    18601 ctagtggaaa acctttggta gaaaatacgt taaagcaggt tgtttccttt acgcgtagca
    18661 ataaaatgac ggctacagac ttaaaagaaa cagctaaaaa gttactgact tatgtgagca
    18721 tcagttctcc aaatttgaca gaacgccagc tggcggatta ctatttggct gatcctgaaa
    18781 tctataaaaa aacagtggaa gctctcccaa gtgagaaacg cttggattca gatggcaatc
    18841 gtctatccga atcagaactg tataacaatg cggtcgatag tgtccaaaca agtcaactaa
    18901 actatacaga ggatgaaaag aaagaaatct atctttttag tcagttaaat gctgttggaa
    18961 actttgcgac aggaaccatt gctacagatc ctctaaatga ttctcaggtg gctgttattg
    19021 cctctatttc aaaggagatg cctggcatta gtatttctac ttcttgggat agaaaggttt
    19081 tggaaacttc cctttcttct atagttggga gtgtatccag tgaaaaagct ggtctcccag
    19141 cggaagaagc agaagcctat cttaaaaaag gctattctct aaatgatcgt gtaggaacct
    19201 cctatttgga aaagcaatat gaagagacct tacaaggaaa acgctcggta aaagaaatcc
    19261 atctggataa atatggcaat atggaaagcg tggatacaat tgaggaaggt agtaagggaa
    19321 acaatatcaa actgaccatt gatttggctt tccaagatag cgtggatgct ttactgaaaa
    19381 gttatttcaa ttccgagcta gaaaatggtg gagccaagta ttctgaaggt gtctatgcag
    19441 tcgcccttaa cccaaaaaca ggtgcggttt tgtctatgtc agggattaaa catgacttga
    19501 aaacgggaga gttgacgcct gattccttgg gaacggtaac caatgtcttt gttccaggtt
    19561 cggttgtcaa ggcggcgacc atcagctcag gttgggaaaa tggagtcttg tcaggaaacc
    19621 agaccttgac agaccagtcc attgtcttcc aaggttcagc tcccatcaat tcttggtata
    19681 ctcaggctta cggttcattc cctatcacag cggtccaagc tctggagtat tcatcaaata
    19741 cctatatggt ccaaacagcc ttaggtctta tggggcaaac ctatcaaccc aatatgtttg
    19801 tcggcaccag caatctagag tctgctatgg agaaactgcg ttcaaccttt ggcgaatatg
    19861 gcttgggtac tgcgacagga attgacctac cagatgaatc tactggattt gttcccaaag
    19921 agtatagctt tgctaattac attactaatg cctttgggca gtttgataac tatacgccga
    19981 tgcagttggc tcagtatgta gcaactattg caaataatgg tgttcgtgtg gctcctcgta
    20041 ttgttgaagg catttatggt aataatgata agggaggact gggtgacttg attcagcaac
    20101 tgcaaccgac agagatgaat aaggtcaata tatccgactc cgatatgagc atcttgcacc
    20161 aaggttttta tcaggttgcc catggtacta gtgaattgac aactggacgt gccttttcaa
    20221 atggcgcctt ggtatccatt agcggaaaaa caggtacagc cgaaagctat gtggcagatg
    20281 gtcagcaagc aaccaatacc aatgcggtgg cctatgcccc atctgataat ccccaaatcg
    20341 ctgttgcagt ggtctttcct cataatacca atctaacaaa tggtgtagga ccttccattg
    20401 cgcgtgacat tatcaatctg tatcaaaaat accatccaat gaactagaaa ggaaattatg
    20461 ctttatccaa cacctattgc caagttgatt gacagttatt ctaagttacc aggtatcggg
    20521 attaagacgg ctacgcgtct ggccttttat acgattggga tgtctgctga tgatgtcaat
    20581 gaatttgcaa aaaatctcct ttctgctaag agagaattga catattgttc tatttgtgga
    20641 cgtttgacag acgacgatcc ttgttctatc tgtactgatc cgactcgtga ccagacaaca
    20701 attttagttc ttgaggatag tagagatgtg gcagccatgg aaaatatcca agaataccat
    20761 ggactctatc atgtccttca tggcctcatt tctcctatga atggtatcag tccggacgat
    20821 atcaatctca agagccttat gactcgtctt atggatagtg aagtttcaga agtgattgtg
    20881 gcgactaatg ctacagcgga tggtgaagcg acttccatgt atctttcacg tttgctcaag
    20941 ccggctggta tcaaggttac gcgtctagca cgaggtctcg ctgtgggagc ggacattgag
    21001 tatgcggacg aagtgacact cttacgagcg attgaaaatc ggacagagtt gtaagtgtag
    21061 gcaaatttac gaactccatt catttataaa aaatcaaaga ggctgaaaat cgttcctatc
    21121 ggcctctttt tgtatagtgt gatgagtagg atcaggttca agttttaaaa aaccaagcaa
    21181 atatgatata ctaaagagcg agtattctag tagaattagg acaaataata tgaaacaaac
    21241 gattattctt ttatatggtg gacggagtgc ggaacgcgaa gtctctgtcc tttcagctga
    21301 gagtgtcatg cgtgcggtca attacgaccg tttcacagtc aagactttct ttatcagtca
    21361 gtcaggtgac tttatcaaaa cacaggaatt tagtcatgct ccggggcaag aagaccgtct
    21421 catgaccaat gaaaccattg attgggataa gaaagttgca ccaagtgcta tctacgaaga
    21481 aggtgcagtg gtctttccag tccttcacgg gccaatggga gaagatggct ctgttcaagg
    21541 attcttggaa gttttgaaaa tgccttacgt tggttgcaac attttgtcat caagtcttgc
    21601 catggataaa atcacgacta agcgtgttct ggaatctgct ggtattgccc aagttcctta
    21661 tgtggctatc gttgaaggcg atgatgtgac tgctaaaatc gctgaagtgg aagaaaaatt
    21721 ggcttatcca gtcttcacta agccgtcaaa catggggtct agtgtcggta tttctaagtc
    21781 tgaaaaccaa gaagaactcc gtcaagcctt aaaacttgcc ttccgatatg acagccgtgt
    21841 cttggttgag caaggagtga atgcccgtga aattgaggtt ggcctcttgg gtaactacga
    21901 tgtcaagagc acgctacctg gagaagttgt caaggacgtt gccttttatg actacgatgc
    21961 caagtatatt gataacaaga ttactatgga tattcctgcc aaaatcagtg atgatgtggt
    22021 ggctgtcatg cgtcaaaatg cagaaacagc cttccgtgcc attggtggcc ttggtctatc
    22081 tcgttgcgat ttcttctata cagataaggg agagattttt ctcaacgagc tcaataccat
    22141 gccaggtttt acccagtggt ctatgtaccc actactttgg gacaatatgg ggatcagcta
    22201 cccagaacta atcgagcgtt tggttgacct tgccaaggaa agttttgaca agcgcgaagc
    22261 gcatttgata taaaatgaaa gagagggtag aagccagaac catcactgca cggtgactag
    22321 agttctcgga cttcagccct ttttaaagga gtagaaatga aattaacaat ccatgaaatt
    22381 gcccaagttg ttggagccaa aaatgatatc agtatctttg aggacaccca gttagaaaaa
    22441 gctgagtttg atagtcgttt gattggaact ggagatttat ttgtgccact taaaggtgcg
    22501 cgtgatggcc atgactttat tgaaacagcc tttgaaaatg gtgcagcagt aaccttgtct
    22561 gagaaagagg tctcaaatca tccttacatt ctagtagatg atgttttggc agcctttcaa
    22621 tccctagcat cctactatct tgaaaaaacg actgttgatg tctttgctgt tacaggttca
    22681 aatggcaaga caacgactaa ggatatgttg gcgcatttac tgtcaacaag atacaagacc
    22741 tacaaaacac aaggcaatta caataatgag attggccttc cttacacagt tcttcatatg
    22801 cctgaaggaa cagaaaagtt ggttttggag atgggacagg atcacttggg agatattcat
    22861 ctcttgtctg aattggctcg tccaaaaaca gccatcgtga ccttggttgg agaagctcat
    22921 ttggcctttt tcaaagaccg ttctgagatt gctaaaggaa aaatgcaaat tgcagacgga
    22981 atggcttcag gttccttgct tttagcgccg gctgacccta tcgtagagga ctatttgcca
    23041 actgataaaa aggtggttcg ttttggtcaa ggagcagagc tgggaattac cgacttggtt
    23101 gagcgcaaag atagtctgac cttcaaggtc aatttcttag agcaagccct tgatttgcca
    23161 gtaactggca agtacaatgc gacaaatgct atgattgcat cctatgttgc cttgcaagaa
    23221 ggagtttcag aggagcaaat tcgtttggcc ttccaacatc ttgaattgac gcgtaaccgt
    23281 accgagtgga agaaagcagc caatggagca gatatcctgt cagatgttta taatgccaat
    23341 ccaactgcta tgaaactgat tttagagact ttctctgcca ttccagccaa tgaaggtggc
    23401 aagaaaattg cagtgttggc ggatatgaag gagcttggtg accagtctgt tcaacttcat
    23461 aatcagatga ttttgagcct ctccccagat gtgcttgata tcgttatttt ctatggagaa
    23521 gatattgctc agttggctca attggccagt caaatgtttc caatcggcca cgtttactac
    23581 ttcaagaaaa cagaagacca ggatcaattt gaagacctag tcaagcaggt taaggaaagc
    23641 cttggagctc atgaccaaat cctgctcaaa ggctctaact ctatgaatct agccaagttg
    23701 gtagaaagtt tagaaaatga agacaagtga ttttgtcaag tatttgcaaa gaatgattgc
    23761 cattacagat actggcttaa cctttacaaa agatccgttt gaccgtgagc gctacgaaga
    23821 cttgcgaagt ctgttatctg aaatgttgaa tcaggtatca gacctggatg cagaagaagt
    23881 agcagaagtc ttgaaaccaa cttcagctta tgcgactccc ttaatggacg tccgtgcttg
    23941 gattgttgag gatgagaaga tttgtctggt taggggacaa ggagaggata gttgggcttt
    24001 gccaggtggc tttggtgaag tcggctattc tccaactgaa aatattctca aggaaattga
    24061 agaagaaacc ggttttaaag ccaaagttga aagactgcta gctgtttttg ataccaatcg
    24121 tttccaacta cagagtaaac aatatgcaaa gtttgttttt gaatgtaagt ttctcgatgg
    24181 acaattccaa gaaaatcaag aaattgcaga tcttcaattt tttgccattg accaactgcc
    24241 gaacttatct gaaaaacgca ttaccaagga gcaaatagag cttctttggc aggtttatca
    24301 aggtcatagg gggcaatatc ttgactaaga agatgattat cgtattttta aatccatttt
    24361 taacaactag catggtataa taatatgcag gaaaattttg aattatgagg aagactagat
    24421 gaatttatgg gatattttct ttacgactca ggcaaccgag ccgcccaaat ttgacctttt
    24481 ttggtatgtt agcctattta cgctcttagc cttaaccttt tatacagccc atcgctatcg
    24541 tgaaaagaag gtttaccaac gatttttcca aatcttgcag actgttcagt taatccttct
    24601 ttatggttgg tactgggtca atcatatgcc actgtcagaa agcctaccct tttaccattg
    24661 ccgtatggct atgtttgtgg tactcttgct tcctggtcag tccaaatata aacaatactt
    24721 tgcattattg ggaacatttg ggacattagc agcctttgtt tatccagtgc cagatgctta
    24781 cccttttcca catatcacca ttctatcctt tatctttggt catttagcac tcttggggaa
    24841 ctctctagtt tatctattga gacagtataa tgcgcgattg ctggatgtga agggaatttt
    24901 tctcatgacc tttgccctaa atgccttgat ttttgtggtc aatttggtga caggtggcga
    24961 ttacggattt ttgacaaaac cgccattggt tggggatcac ggtctagtag ctaattattt
    25021 acttgtttca attgtgctgg tagctactat cagtttgact aagaaaatct tagaattctt
    25081 tttagctcaa gaagcagaaa aaatgattgc aaaggaagct taacacagag ctttcttttt
    25141 tgctcttaga gagtttttac aagcagctta taaaataaga atttctgaat agacaaactc
    25201 aaaaaatggc tgggaaattt aggaaaaaag caagcacgat taaatttttt gtgttataat
    25261 attttgtgaa tagctatgcc tatgtttagc tatggaataa tacgaagtgc gaaacttgga
    25321 agatagagag gaagcgatgt aatggctaga gaaggctttt ttacaggtct agatattgga
    25381 acaagctctg tcaaggtgct tgtggccgag cagagaaatg gtgaattaaa tgtaattggc
    25441 gtgagtaatg ccaaaagtaa aggtgtaaag gatggaatta ttgttgatat tgatgcagca
    25501 gcaactgcta tcaagtcagc catttcccaa gcggaagaaa aggcaggcat ttcgattaaa
    25561 tcagtgaatg tcggcttgcc tggtaatctt ttgcaggtag aaccaactca ggggatgatt
    25621 ccagtaacat ctgatactaa ggaaattacg gatcaagatg ttgaaaatgt tgtcaaatca
    25681 gctttgacaa agagtatgac acctgaccgt gaagtcatta cctttattcc tgaagaattt
    25741 attgtggatg gtttccaagg gattcgtgac ccacgtggta tgatgggggt tcgccttgaa
    25801 atgcgtggtt tgctttatac aggacctcgt actatcttgc acaatttgcg taagacggtt
    25861 gagcgtgcag gtgttcaggt tgaaaatgtt atcatttcac cactagcaat ggttcagtct
    25921 gttttgaacg aaggggaacg tgaatttggt gctacagtga ttgatatggg ggcaggtcaa
    25981 acgactgtcg ctacaatccg taatcaagaa ctccagttca cacatattct ccaagaaggt
    26041 ggagattatg taactaaaga tatctccaag gttttgaaaa cctctcgcaa attagcggaa
    26101 ggcttgaaac tgaattacgg ggaagcctat ccgcctcttg caagcaaaga aaccttccaa
    26161 gtagaggtta ttggagaagt ggaagcagtc gaagtgacgg aagcctactt gtcagaaatt
    26221 atttctgcac gaatcaagca catccttgaa caaatcaagc aagaattaga tagaaggcgt
    26281 ctattggacc tccctggtgg tattgtctta atcggtggga atgccatttt accaggtatg
    26341 gttgagcttg ctcaggaagt ctttggcgtc cgtgtcaagc tttatgttcc aaatcaagtt
    26401 ggtatccgta atccagcctt tgcgcatgtg attagtttat cagaatttgc gggtcaatta
    26461 acagaagtta atcttttggc tcagggagcg ataaaaggtg agaatgactt aagtcatcag
    26521 ccaattagtt ttggtgggat gctgcaaaaa acagctcagt ttgtacaatc aacgcctgtt
    26581 caaccagctc ctgctccaga agtagagccg gtggcgccta cagaaccaat ggcggatttc
    26641 caacaagctt cacaaaataa accgaaatta gcagatcgtt tccgtggctt gatcggaagc
    26701 atgtttgacg aataaagagg aaaaataaat tatgacattt tcatttgata cagctgctgc
    26761 tcaaggggca gtgattaaag taattggtgt cggtggaggt ggtggcaatg ccatcaaccg
    26821 tatggtcgac gaaggtgtta caggcgtaga atttatcgca gcaaacacag atgtacaagc
    26881 attgagtagt acaaaagctg agactgttat tcagttggga cctaaattga ctcgtggttt
    26941 gggtgcagga ggtcaacctg aggttggtcg taaagccgct gaagaaagcg aagaaacact
    27001 gacggaagct attagtggtg ccgatatggt cttcatcact gctggtatgg gaggaggctc
    27061 tggaactgga gctgctcctg ttattgctcg tatcgccaaa gatttaggtg cgcttacagt
    27121 tggtgttgta acacgtccct ttggttttga aggaagtaag cgtggacaat ttgctgtaga
    27181 aggaatcaat caacttcgtg agcatgtaga cactctattg attatctcaa acaacaattt
    27241 gcttgaaatt gttgataaga aaacaccgct tttggaggct cttagcgaag cggataacgt
    27301 tcttcgtcaa ggtgttcaag ggattaccga tttgattacc aatccaggat tgattaacct
    27361 tgactttgcc gatgtgaaaa cggtaatggc aaacaaaggg aatgctctta tgggtattgg
    27421 tatcggtagt ggagaagaac gtgtggtaga agcggcacgt aaggcaatct attcaccact
    27481 tcttgaaaca actattgacg gtgctgagga tgttatcgtc aacgttactg gtggtcttga
    27541 cttaaccttg attgaggcag aagaggcttc acaaattgtg aaccaggcag caggtcaagg
    27601 agtgaacatc tggctcggta cttcaattga tgaaagtatg cgtgatgaaa ttcgtgtaac
    27661 agttgtcgca acgggtgttc gtcaagaccg cgtagaaaag gttgtggctc cacaagctag
    27721 aactgctact aactaccgtg agacagtgaa accagctcat tcacatggct ttgatcgtca
    27781 ttttgatatg gcagaaacag ttgaattgcc aaaacaaaat ccacgtcgtt tggaaccaac
    27841 tcaggcatct gcttttggtg attgggatct tcgccgtgaa tcgattgttc gtacaacaga
    27901 ttcagtcgtt tctccagtcg agcgctttga agccccaatt tcacaagatg aagatgaatt
    27961 ggatacacct ccatttttca aaaatcgtta agtaaatgaa tgtaaaagaa aatacagaac
    28021 ttgtttttcg agaagttgca gaggctagtc tgagtgctca tcgagagagt ggttcggtct
    28081 ctgtcattgc agttaccaag tatgtagatg taccgacagc ggaagccttg cttccgctag
    28141 gtgttcatca tatcggtgaa aatcgtgtag ataagtttct ggaaaaatat gaagctttaa
    28201 aagatcgaga tgtgacttgg catttgattg gtaccttgca aagacgtaag gtgaaagata
    28261 tcattcaata cgttgattat ttccatgcat tggactcagt aaagctagca ggggaaattc
    28321 aaaaaagaag tgaccgagtc atcaagtgtt tccttcaagt aaatatttct aaagaagaaa
    28381 gcaaacacgg tttttcgaga gaggaactgc tggaaatctt gccagagtta gccagactag
    28441 ataagattga atatgttggt ttaatgacga tggcaccttt tgaggctagc agtgagcagt
    28501 tgaaagagat tttcaaggcg gcccaagatt tacaaagaga aattcaagag aaacaaattc
    28561 caaatatgcc tatgaccgag ttaagtatgg gaatgagtcg tgattataaa gaagcgattc
    28621 aattcggttc cacttttgtt cgtataggta catcattttt taagtaggag agaaccatgt
    28681 ctttaaaaga tagattcgat agatttatag attattttac ggaggatgag gattcaagtc
    28741 tcccttatga aaaaagagat gagcctgtgt ttactccagt aaattcttca caggaaccgg
    28801 ctctcccaat gaatcaacct tcacagtcgg ctggtacaaa agagaacaat atcaccagac
    28861 ttcatgcaag acaacaggaa ttggcaaatc agagtcagcg tgcaacggat aaggtcatta
    28921 tagatgttcg ttatcctaga aaatatgagg atgcaacaga aattgttgat ttattggcag
    28981 gaaacgaaag tatcttgatt gattttcagt atatgacaga ggtgcaggct cgtcgttgtt
    29041 tggactattt ggatggagct tgtcatgttt tagctggaaa tttgaaaaag gtagcttcta
    29101 ccatgtattt gttgacacca gtgaatgtta ttgtaaatgt tgaagatatc cgtttaccag
    29161 atgaagatca acagggtgag ttcggttttg atatgaagcg aaatagagta cgataatgat
    29221 ttttttaatt cgtatgattt ataatgcagt ggatatttac tccctgattt tggtagcctt
    29281 cgctgtcatg tcttggtttc caggtgccta cgaatccagt ttaggtcgtt ggattgtagc
    29341 gttggtgaaa ccagtgcttg ctcccttgca acgcctgcct ttacagatag cgggtcttga
    29401 tttatctgtt tgggtcgcga ttgttttggt tcgattttta ggagaaaacc tagtgcgttt
    29461 tctggcgatg ataggatgaa taaagggatt tatcagcatt tctccataga agatcgtcca
    29521 tttcttgaca agggaatgga atggataaag aaggtagaag atagctatgc tcctttttta
    29581 actcctttta tcaatcctca tcaggagaag ctattaaaga ttttggccaa aacctatggt
    29641 cttgcttgta gcagtagtgg ggaattcgtc tcgagtgagt atgttcgagt tttattatac
    29701 ccagattatt tccaaccaga gttttcagat tttgaaatat ctctccagga aattgtgtat
    29761 tccaataaat ttgaacattt aacgcatgct aagattttag ggacagtcat caatcaatta
    29821 gggattgaac ggaaactttt tggagatatc ctagtagatg aagaacgggc gcagattatg
    29881 attaatcagc agtttcttct tctctttcaa gatggactaa agaaaattgg tcgtatacct
    29941 gtttcgctgg aggaacgtcc tttcaccgag aaaatagata agctagaaca gtatcgagaa
    30001 ctggatttat ctgtgtttag ttttcgatta gatgttcttt tatcaaatgt tttgaaacta
    30061 tctaggaatc aagcaaacca gttgattgaa aagaaacttg tccaagtaaa ttatcatgtg
    30121 gtagacaaat cagattacac tgttcaagtt ggagacttga ttagtgtgag aaaatttggc
    30181 cgcttgagat tacttcaaga taagggacaa acgaaaaaag agaagaaaaa aataaccgtc
    30241 cagttattat taagtaagtg aggaatagaa tgccaattac atcattagaa ataaaggaca
    30301 agacttttgg aactcgattc agaggttttg atccagaaga agtcgatgaa tttttagata
    30361 ttgtggttcg tgattacgaa gatcttgtgc gtgcgaatca tgataaaaat ttgcgtatta
    30421 agagtttaga agagcgtttg tcttactttg atgaaataaa agattcattg agccagtctg
    30481 tattgattgc tcaggataca gctgagagag tgaaacaggc ggcgcatgaa cgttcaaaca
    30541 atatcattca tcaagcagag caagatgcgc aacgcttgtt ggaagaagct aaatataagg
    30601 caaacgagat tcttcgtcaa gcaactgata atgctaagaa agtcgctgtt gaaacagaag
    30661 aattgaagaa caagagccgt gtcttccacc aacgtctcaa atctacaatt gagagtcagt
    30721 tggctattgt tgaatcttca gattgggaag atattctccg tccaacagct acttatcttc
    30781 aaaccagtga tgaagccttt aaagaagtgg ttagcgaagt acttggagaa ccgattccag
    30841 ctccaattga agaagaacca attgatatga cacgtcagtt ctctcaagca gaaatggaag
    30901 aattacaagc tcgtattgag gtagccgata aagaattgtc tgaatttgaa gctcagatta
    30961 aacaggaagt ggaaactcca actcctgtag tgagtcctca agttgaagaa gagcctctgc
    31021 tcatccagtt ggcccaatgt atgaagaacc agaagtagct ccagtgcatc cgacaggtcc
    31081 aacaccagct acagaaactg ttgattcagc accgggattt gaagcaccgc aagaatctgt
    31141 tacaatttta taagaaatat tctgagaaca atatcttatc cttatattcc cagcgagcag
    31201 gagatggtgt gagtcctgca ttccctatcg ataagattat cctctcaaaa actcaagtct
    31261 gaagctagta agatttgacg ttccccacgt tacgggataa gagggagaaa gactaaaact
    31321 ttttccgaat aaaggtggta ccacgatttt cgtccttttt ggaagtcgtg gtttttaatt
    31381 tgttattatt tataaaggag ataccatgaa actcaaagac acccttaatc ttgggaaaac
    31441 tgaattccca atgcgtgcag gccttcctac caaagagcca gtttggcaaa aggaatggga
    31501 agatgcaaaa ctttatcaac gtcgtcaaga attgaaccaa ggaaaacctc atttcacctt
    31561 gcatgatggc cctccatacg ctaacggaaa tatccacgtt ggacatgcta tgaacaagat
    31621 ttcaaaagat atcattgttc gttctaagtc tatgtcagga ttttacgcac catttattcc
    31681 tggttgggat actcatggtc tgccaatcga gcaagtattg tcaaaacaag gtgtcaaacg
    31741 taaagaaatg gacttggttg agtacttgaa actttgccgt gagtacgctc tttctcaagt
    31801 agataaacaa cgtgaagatt ttaaacgttt gggtgtttct ggtgactggg aaaatccata
    31861 tgtgaccttg actcctgact atgaagcagc tcaaattcgt gtatttggtg agatggctaa
    31921 taagggttat atctaccgtg gtgccaagcc agtttactgg tcatggtcat ctgagtcagc
    31981 ccttgctgaa gcagagattg aataccatga tttggtttca acttcccttt actatgccaa
    32041 caaggtaaaa gatggcaaag gagttctaga tacagatact tatatcgttg tctggacaac
    32101 gactccattt accatcacag cttctcgtgg tttgacggtt ggtgcagata ttgattacgt
    32161 tttggttcaa cctgctggtg aagctcgtaa gtttgtcgtt gctgctgaat tattgactag
    32221 cttgtctgag aaatttggct gggctgatgt tcaagttttg gaaacttacc gtggccaaga
    32281 actcaaccac atcgtaacag aacacccatg ggatacagct gtagaagagt tggtaattct
    32341 tggtgaccac gttacgactg actctggtac aggtattgtc catacagccc ctggttttgg
    32401 tgaggacgat tacaatgttg gtattgctaa taatcttgaa gtcgcagtga ctgttgatga
    32461 acgtggtatc atgatgaaga atgctggtcc tgaatttgaa ggtcaattct atgaaaaggt
    32521 agttccaact gttattgaaa aacttggtaa cctccttctt gcccaagaag aaatctctca
    32581 ctcatatcca tttgactggc gtactaagaa accaatcatc tggcgtgcag ttccacaatg
    32641 gtttgcctca gtttctaaat tccgtcaaga aatcttggac gaaattgaaa aagtgaaatt
    32701 ccactcagaa tggggtaaag tccgtcttta caatatgatc cgtgaccgtg gtgactgggt
    32761 tatctctcgt caacgtgctt ggggtgttcc acttcctatc ttctacgctg aagatggtac
    32821 agctatcatg gtagctgaaa ctattgaaca cgtagctcaa ctttttgagg aacatggttc
    32881 aagcatttgg tgggaacgtg atgccaaaga cctcttgcca gaaggattta ctcatccagg
    32941 ttcaccaaac ggcgagttca aaaaagaaac tgatatcatg gacgtttggt ttgactcagg
    33001 ttcatcatgg aatggagtgg tggtaaaccg tcctgaattg acttatccag ctgaccttta
    33061 ccttgaaggt tctgaccaat accgtggttg gttcaactca tcactcatta catctgttgc
    33121 caaccatggc gtagcacctt acaaacaaat cttgtcacaa ggttttaccc ttgatggtaa
    33181 aggtgagaag atgtctaaat cacttggaaa taccattgct ccaagtgatg ttgaaaaaca
    33241 atttggtgca gaaatcttgc gtctctgggt aacaagtgtt gactcaagca atgacgtgcg
    33301 tatctctatg gatattttga gccaagtttc tgaaacttac cgtaagattc gtaacactct
    33361 tcgtttcttg attgccaata catctgactt taacccagct caagatgtag tcgcttacga
    33421 tgaacttcgt tcagttgata agtacatgac tcttcgcttt aaccagcttg tcaagaccat
    33481 tcgtgatgcc tatgcggact ttgaattctt gacaatctac aaggccttgg tgaactttat
    33541 caacgttgac ttgtcagcct tctaccttga ttttgccaaa gatgttgttt acattgaagg
    33601 tgccaaatca ttggaacgcc gtcaaatgca gactgttttc tatgacattc ttgtcaaaat
    33661 caccaaactc ttgacaccaa tccttcctca cactgcggaa gaaatctggt catatcttga
    33721 gtttgaagct gaagacttcg ttcaattgtc agaattgcca gaagctcaaa cttttgctaa
    33781 tcaagaagaa gtcttggata catgggcagc cttcatggac ttccgtggac aagctcaaaa
    33841 agccttggaa gaagctcgta atgcaaaagt tatcgggaaa tcgcttgaag cacacttgac
    33901 agtttatcca aatgaagttg tgaaaactct actcgaagca gtaaacagca atgtggctca
    33961 acttttgatc gtgtcagact tgaccatcgc agaagggcca gctccagaag ctgctgttag
    34021 cttcgaagat gtagccttca cagttgaacg cgctgcaggt caagtatgtg accgttgccg
    34081 tcgtatcgac ccaacaacag cagaacgcag ctaccaggca gtcatctgtg accactgtgc
    34141 aagcatcgta gaagaaaact ttgcggaagc agtcgcagaa ggatttgaag agaaataagg
    34201 ttgaaaagtc taggcaaaat tcaatttgag aagaaaagac aactaatttt atagtctatt
    34261 aaacgcattg tatcacgttt ttgaatacct gatatgatgc gttttttatt tattttaaaa
    34321 atttgcgagg tatgactttt tatactcaac aagaatcaaa gagaaactta gcaagctaac
    34381 agtagtaaga taaaatagga atttgatatt aggg
//
LOCUS       DAVKZI010000022        33195 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKZI010000022 DAVKZI010000000
VERSION     DAVKZI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33195
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.022"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(167..517)
                     /locus_tag="VXB18_001214"
     CDS             complement(167..517)
                     /locus_tag="VXB18_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382422.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(657..992)
                     /locus_tag="VXB18_001215"
     CDS             complement(657..992)
                     /locus_tag="VXB18_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382423.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(1083..2393)
                     /gene="der"
                     /locus_tag="VXB18_001216"
     CDS             complement(1083..2393)
                     /gene="der"
                     /locus_tag="VXB18_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0382424.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(2407..3120)
                     /locus_tag="VXB18_001217"
     CDS             complement(2407..3120)
                     /locus_tag="VXB18_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0382425.1"
                     /translation="MTETIKLMKAHTSVRRFKEQVLPQEDLTEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLKQKKLL"
     gene            complement(3117..4013)
                     /gene="dnaI"
                     /locus_tag="VXB18_001218"
     CDS             complement(3117..4013)
                     /gene="dnaI"
                     /locus_tag="VXB18_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0382426.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTTWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(4014..5183)
                     /locus_tag="VXB18_001219"
     CDS             complement(4014..5183)
                     /locus_tag="VXB18_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0382427.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEYLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEAIIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(5184..5657)
                     /gene="nrdR"
                     /locus_tag="VXB18_001220"
     CDS             complement(5184..5657)
                     /gene="nrdR"
                     /locus_tag="VXB18_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0382428.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5797..6162
                     /locus_tag="VXB18_001221"
     CDS             5797..6162
                     /locus_tag="VXB18_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0382429.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELVAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            6167..6862
                     /locus_tag="VXB18_001222"
     CDS             6167..6862
                     /locus_tag="VXB18_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382430.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            6879..7646
                     /locus_tag="VXB18_001223"
     CDS             6879..7646
                     /locus_tag="VXB18_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382431.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(7999..9198)
                     /locus_tag="VXB18_001224"
     CDS             complement(7999..9198)
                     /locus_tag="VXB18_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382432.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(9195..10088)
                     /locus_tag="VXB18_001225"
     CDS             complement(9195..10088)
                     /locus_tag="VXB18_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382433.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            10205..10285
                     /locus_tag="VXB18_001226"
                     /pseudo
     CDS             10205..10285
                     /locus_tag="VXB18_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10770..10983
                     /locus_tag="VXB18_001227"
                     /pseudo
     CDS             10770..10983
                     /locus_tag="VXB18_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11398..12015
                     /locus_tag="VXB18_001228"
     CDS             11398..12015
                     /locus_tag="VXB18_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0382434.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12058..12945)
                     /locus_tag="VXB18_001229"
     CDS             complement(12058..12945)
                     /locus_tag="VXB18_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0382435.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIEFNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(13094..14977)
                     /locus_tag="VXB18_001230"
     CDS             complement(13094..14977)
                     /locus_tag="VXB18_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0382436.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSIPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            15354..16808
                     /locus_tag="VXB18_001231"
     CDS             15354..16808
                     /locus_tag="VXB18_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0382437.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRFQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            16789..17754
                     /locus_tag="VXB18_001232"
     CDS             16789..17754
                     /locus_tag="VXB18_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0382438.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(17789..19063)
                     /locus_tag="VXB18_001233"
     CDS             complement(17789..19063)
                     /locus_tag="VXB18_001233"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0382439.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQIANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(19063..20235)
                     /locus_tag="VXB18_001234"
     CDS             complement(19063..20235)
                     /locus_tag="VXB18_001234"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0382440.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(20366..20614)
                     /locus_tag="VXB18_001235"
     CDS             complement(20366..20614)
                     /locus_tag="VXB18_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382441.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(20682..21308)
                     /locus_tag="VXB18_001236"
                     /pseudo
     CDS             complement(20682..21308)
                     /locus_tag="VXB18_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21370..21819)
                     /locus_tag="VXB18_001237"
     CDS             complement(21370..21819)
                     /locus_tag="VXB18_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0382442.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(21821..22579)
                     /locus_tag="VXB18_001238"
     CDS             complement(21821..22579)
                     /locus_tag="VXB18_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0382443.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(22694..24673)
                     /gene="pknB"
                     /locus_tag="VXB18_001239"
     CDS             complement(22694..24673)
                     /gene="pknB"
                     /locus_tag="VXB18_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0382444.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(24670..25410)
                     /locus_tag="VXB18_001240"
     CDS             complement(24670..25410)
                     /locus_tag="VXB18_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0382445.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(25425..26738)
                     /gene="rsmB"
                     /locus_tag="VXB18_001241"
     CDS             complement(25425..26738)
                     /gene="rsmB"
                     /locus_tag="VXB18_001241"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0382446.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(26731..27666)
                     /locus_tag="VXB18_001242"
     CDS             complement(26731..27666)
                     /locus_tag="VXB18_001242"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0382447.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMIFRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEDQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(27679..30075)
                     /locus_tag="VXB18_001243"
     CDS             complement(27679..30075)
                     /locus_tag="VXB18_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0382448.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRSGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(30141..30455)
                     /locus_tag="VXB18_001244"
     CDS             complement(30141..30455)
                     /locus_tag="VXB18_001244"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0382449.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(30480..31106)
                     /gene="gmk"
                     /locus_tag="VXB18_001245"
     CDS             complement(30480..31106)
                     /gene="gmk"
                     /locus_tag="VXB18_001245"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0382450.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(31236..32849)
                     /locus_tag="VXB18_001246"
     CDS             complement(31236..32849)
                     /locus_tag="VXB18_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0382451.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILVQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT         9373 a         7528 c         6386 g         9908 t
ORIGIN      
        1 tcaattaggg gatctaaagc attttatacc aatgttttat aagttgtatt gtattattcc
       61 atattcaatc cactatacaa gatgaatatt tctctcaagt ttcataatca aaataaaaat
      121 gactgtatct atagctccat aaacaaatca tagatacagt cattttttag ttcctacacc
      181 ttcctttatg cacaccttta gacttcccta gttcccgtct caagtcaagc atttttttga
      241 aacagatata gtctaaccag tcactagcaa aagcgataag tagtaataat agccaaatac
      301 cccataactt gatatctgtc aaatttctca agacgatatt gaaaaacaga actgaaaaaa
      361 ctgtccaagc aaggctaaaa agagcataga gggtgatgta aatccagtaa aaatagtaaa
      421 aaattgggaa aaatttactt tctctattat ccttgtcaat ccagctgaaa aagtaaaaac
      481 agggtaataa gattatcatt ttaaacaagt gttccatcac aagcctcctt ttttaaattg
      541 ttttctttag tttcgttcta ttaaatgtta ttaccaatat aaaccttgga atagcgtgta
      601 ataaatgatt ttagaggtac cataagccac ctcctacaaa tagaaaccga tataaatcaa
      661 tgccttccac ccttagactt ccctagttcc tgtctcaagc gaaacatttc tttgaaacag
      721 gaataagtta accaattcat accaatagct agcagaataa aaagaaacca aatgccccat
      781 aacttgatat ctgtcacatt tctcaagacg gtattgaaaa acagaactga aacaactgtc
      841 caagcaaggc taaaaagaga atagaagggg atgtaaatcc agtaaaaata ataaaaaatt
      901 ggaaaaaact tactatttct gttggccttt tcaatccagt tatcaaaata aaagtacggt
      961 gctaaaagta agaatttaaa caaatgttcc atcaccgaca tccccctcct tcttttaata
     1021 gcgttttcta ttattttatt atatcaaaag aatctggaaa tgtcattcca gattctactt
     1081 ttttatttac gctttcttgc gatgagatga atcggtgttc cctcaaagac aaaggccttg
     1141 cggatttgat tttccaagaa acgtaggtaa gaaaagtgca tgagttcttc ttcgttgaca
     1201 aagataacaa aggttggtgg tttggttgcc acttgggtcg catagaaaat cttgagacgt
     1261 tttcctttgt ctgtcggtgt tgggttgatg gcaatggcat ccatgatgac atcgttcaag
     1321 acagctgatg gaatacgtgt attttgactt tcgctgattt gcttaatcat cccaggaagt
     1381 ttgtggagac gttgcttggt taaagctgat acaaagataa tcggtgcgta aggcaggtat
     1441 tggaactgct cacggatatc ttcttcccag tttttcatag tgtggttatc tttttcaagc
     1501 gtatcccact tgttgaccac gataatcatc cctttaccag cttcatgagc aaatccagcg
     1561 atacgcttgt cgtattcacg aatcccctct tccgcattga tgaccattaa gaccacatct
     1621 gaacggtcaa tagcacgcat ggcacgcatg acagagtact tctcagtatt ttcataaacc
     1681 ttaccagact tacgcatacc agccgtatca atcatggtaa actcttgacc atctgtatct
     1741 gtaaagtggg tatcaatagc gtcacgagtt gttccagcaa caggactggc aataacacgg
     1801 tcttcgccca agatagcatt gatcaagctt gattttccaa cgtttggacg accaatcagg
     1861 ctaaacttaa tgacatctgg attttcttcc tcatattcat ttggaagatt ttctacgata
     1921 gcatctagta catcccctgt accgattcca tggacagatg agataggcag tggttcaccc
     1981 aaaccgagag catagaaatc atagatatca tttctcatct cagggttgtc caccttgttg
     2041 actgcgagga taactggttt gtgggtctta taaagcttac gagctacgta ttcgtctgca
     2101 tcagtaattc cttccttacc agacacgaca aaaacgataa catctgcttc ttccatggca
     2161 atttctgcct ggtgcttgat ttgttccatg aaaggagcat ctacatcgtc gattcctcct
     2221 gtatcaatca tactaaaaga gcgattgagc cactcacccg ttgcatagat acggtcacgt
     2281 gtcactcctt cgacatcttc tacaatggag attcgctcac cagcgatccg attaaatagg
     2341 gttgatttcc caacattggg acgtcctaca atggcaatag ttggtagggc cataatttct
     2401 cactttctac aataacttct tctgtttaag attttttcta gttgagcttg gttctgcttg
     2461 gccaaactgt tctgctagac gctgactcca gcttgtggtc gcacgcgctc cagcatagtc
     2521 agcctgcaca cggtcataag cttggattgc ctcagttgac tgttcttggt attcttcctc
     2581 aaagactaca ttatctagtg gcagtctcgg tttcacatca tgagtttgat ttggcacacc
     2641 cagtgccatc ccaaagacag aataggtgta gtcaggtagg ttaaagagct ctgccacttc
     2701 ttcagacttg tatcgaacca aaccgataat cacaccacca tagcccaagc tttcagctgc
     2761 caacaaggca ttttgtccag caagagctgc atcgaccgaa ctaatcaaga gaccttccac
     2821 accttggggt tggaaggtgt cggtatgaag tcgggctccc ttttctgctc ggttcaaatc
     2881 tccgacaaag agaaggaaaa cagcagactg gcgaatggct tcttgaggta ccaattcata
     2941 caaggcatct ttcttctctt ggcttcgtac cacaatcaca gagtaggatt ggaaattctt
     3001 ccaagatgat gccatctggg ctgctgtcag gatttcagtc aaatcttcct gaggaaggac
     3061 ttgctcctta aatctgcgca ctgaagtatg agccttcatc aatttaatgg tttctgtcat
     3121 cgacggttta ctccttctaa acgagtctcc tcagccaaat aacggatgcg ttccatgacg
     3181 cgtctggctt cccaggtttc gtcatttcca tttttccctt tagcgaaatg cttctccaaa
     3241 tcttcaaagt tgaagttaga ggtgaaaaag gtcggtaaat tttcctgcat ccgatattgg
     3301 agaatgacct gcaggatttc atcacgcacc caagtggtgg attgctcggc accaatatca
     3361 tctaaaatca ggacttcaga aagcttaatc tcatccacta aggtcttaac attgccatca
     3421 ctgatagcat ttttgacatc aatgacaaag ctaggatagt ggaggagagt ggatgataca
     3481 ccacgttttt ctgataaatc atgagctagg gcagccacca tgaaactttt acccacacca
     3541 aagtctccat acaagtaaag acctttcaaa ttattggggt aatcgttaac aaattctatc
     3601 attcttttta gaacagttaa gcgctgaaca tcatcacgat aaacatctaa aaaactgaca
     3661 tttttcaggc tagatggaaa attaattaag ttgagacgtt tcttgatagc cgcttctttt
     3721 tcagctgcga ttagttcagg agtttcttca taagaaacat ccgcatagcc atggttcatg
     3781 actaatatag gcttgtagcc tttggcaata taatctgtat ctcctcggag gaatttatct
     3841 ctctcagtga tgtattggtt aaacttggaa atactacggt tcaactcgtc ctgattgagg
     3901 gattcttgct ggacaaaggc cgcaacatca ggatccttca tgattttctg aactaaatct
     3961 tgatagtgaa aacgacttgg ttgacgtttg agtacatctc cgacactttc catctaatca
     4021 cctccgttat ctaattttgc taataattct agggtttggc gttccatctc ttctaattcc
     4081 tcagcggatg acgtattttt atattcagga ttactccatt taggaatatt ggtttttgct
     4141 ggggcagtct gattctgttt ttgtgttttt gctttctgtc ctcgctcacg gatgcgcaag
     4201 actgcctctt ctgccgaatg aatcttttga taggcatagt cattggctac cttcatggca
     4261 tatttctcat tgatatttgc cgaatcgacc ttattaaagg tcaataaaag aatgatattg
     4321 atgacttcgt ccagcaaacc caagccagcc atctgttgca agagttctct ttctgtttgg
     4381 gtaatggttc ccttgcgtgt ttgcttgatt tctgccaaga actgcagggc agttttactt
     4441 ttggcttctt tgataatgat cgcttcctta agactaaagt cagaggaaac tggtttttga
     4501 gcaatttttt cacgcatgcg tttggttgaa ataacctgag aaacagctgt tgacttggcc
     4561 aattgatagg tttcaaacca agtccatttc ttctcctcgg caatggcaaa gaggtttaag
     4621 acatcggact gctcatccgc aaagcgaagt ccatctcgag ccataagctg acgaaaatgg
     4681 tccaagtcaa aatcgttggc cactttcttc ttgagaccaa ggtattcttg actgcctagt
     4741 tctgccaatt ctggaaagac ttgattgagt gagacaggta tttcttcacc atcagcactt
     4801 tcaactttca aatcctccac agctacatcg ccaatctttt tctctaagag tctgcgataa
     4861 acaggatgcc ccaagaagtc ttgactagat agaggagcat ggagggctag ctgataaaca
     4921 tccccctttt gatagagagt caagagatta aaagcagata agattttcaa tgattttatc
     4981 agtctatcca tcccaaagtt gagatgattg aggatacttg aaaaaagata ttcctttcta
     5041 ccattatccc aaaaactaat cgtataaaga taaaggctca gtgcctcctg accgataatc
     5101 gggaggtagc actgtaccag agatgaggta tcttgcgaca cccgattatt ctttagataa
     5161 gaaaaacggt caattggctt catttatctt tcctttttct ttttagagga ctgggtgatt
     5221 tgttggagca agctctctaa ctcactgaca tccttaaaac tacgatagac actagcaaaa
     5281 cgtacatagg taatctcgtc caattcagcc aactcctcca tgacgagtga accaatgtcc
     5341 tcactttgaa tttcattttc atttcgacca cggagtttct gttcgatacg attgactacc
     5401 atgttgattt catcacttga cacaggacgt ttctgggctg agcggataat cccattaaag
     5461 attttatctc tggagaattg ttcccgtgtg ccatcttttt taacaaccac taaggttctt
     5521 tcttctactc gttcgtaggt tgtaaaacgg tgttggcact cgtcgcactc tcgtcttcta
     5581 cgaatggtgt tcccttcttc tgcttggcga ctatcgataa cacttgactt ggtagcccca
     5641 cattttggac aacgcatcct ttccctcctt atcgttttct tttcattata ccatttttta
     5701 agcgattccc aaaacaattc ttctttttgc ttgacaagtt ttttgttttg ttgtattatt
     5761 taattaagac aacaaggtaa aagaaaggag actaagatgt cctggacatt tgacaacaaa
     5821 aaacccatct atttacagat tatggagaaa atcaagcttc agattgtttc ccatacactg
     5881 gaacccaatc aacaacttcc aaccgtgagg gagctagcta gcgaggctgg tgtcaatccc
     5941 aataccatcc aaagagcctt atcagacctt gaacgagaag gatttgtcta cagcaagcga
     6001 acaactggac gatttgtgac taaggataag gagctagtcg cccagtcacg caaacaatta
     6061 tcagaagaag aattggaaca cttcgtttcc tccatgaccc attttggcta tgaaaaagaa
     6121 gaactaccag gcgtagtcag tgattatatt aaaggagttt aagcctatgt cattactagc
     6181 atttgaaaat gtatccaaat catatggagc aacaccagcc cttgaaaatg tttctcttga
     6241 cattccagct ggaaaaattg tcggccttct tgggccaaac ggctcaggaa aaacaaccct
     6301 gattaaacta attaatggcc tcttacaacc agatcaagga cgtgtcctca tcaacgacat
     6361 ggacccaagc ccagcaacca aggccgttgt agcttatttg cctgatacga cctatctcaa
     6421 tgagcaaatg aaggtcaaag aagccctaac ctacttcaag accttctata aagatttcaa
     6481 tcttgaacgc gcccatcatc tacttgcaga cctgggcatt gatgaaaata gtcgtctcaa
     6541 gaaactatca aaaggaaaca aagaaaaggt tcaactgatt ttggttatga gccgtgatgc
     6601 tcgtctctat gttttggatg aacccattgg tggggtggat ccagcagccc gtgcttatat
     6661 cctcaatacc attatcaaca actactcacc aacttctacc gttttgattt ctacccactt
     6721 gatttctgat atcgagccaa tcttggatga aattgtcttc ctaaaagacg gaaaagtcgt
     6781 ccgtcaagga aatgtagatg atattcgcta cgagtcaggt gaatccattg accaactctt
     6841 ccgtcaggaa tttaaggcct aagcaaagga gattatttat gttttggaat ttagttcact
     6901 acgaatttaa aaatgttaac aagtggtatt tagccctcta cgcagccgtg ctagtccttt
     6961 ctgccctcat cggaatacag acacaaggct ttaaaaatct accttaccaa gaaagtcagg
     7021 ctactatgct actttttcta gctacagtct ttggtggctt gatgcttaca cttgcgattt
     7081 caaccatttt cttgattatt aaacgcttca aaggtagtgt ctacgaccga caaggctatc
     7141 tgactttgac cttgccagtt tctgaacacc atatcatcac agccaaacta atcggtgcct
     7201 ttatctggtc attgattagc accgctgtat tggctctaag tgctgttatt attctggctt
     7261 taacagctcc agaatggatt cctctttctt atgtgattac atttgtagaa acacatctcc
     7321 ctcagatctt tcttacaggt atatccttcc tactaaatac catttcagga atcctctgca
     7381 tctacctggc tatttccatt ggacagcttt tcaatgaata ccgtacagca ctcgctgttg
     7441 cagcctacat tggtatccaa atcgtcattg gatttattga acttttcttc aatcttagtt
     7501 ctaatttcta tgtcaattca ctggtaggac tcaatgacca tttctatatg ggagcaggta
     7561 tagccattgt taaagaactc atattcatag ctatctttta tctcggaacc tactacatct
     7621 tgagaaataa ggttaatttg ctttaaataa tttttaccta gatatgtaac atactcatag
     7681 aacaaaagag accaggcaaa aagtttttaa aattagaaaa cgcatagtat caagtgttaa
     7741 aaatccttga tattatgcgt tttttgtgag ctgacttatt tcctttcact atatcgcaaa
     7801 atgaaataag aacggaacga tgggattttg gaattcaaat caatttataa gaatgtttta
     7861 gaagtaatat tatcctattc cagattcagt tcactataca attgagtttt caagcaacct
     7921 gtttacataa tgtgtacata attaggttcg tgattccacc cttttcacct ttaaaaacct
     7981 cgctttcgca aggctcttct atttataaga taaggcacgt ttaaaggttt tccaaatccc
     8041 taaatcatcc gtttgaagaa cgagactagc atacatgcgt ccgataaatc ctgttgctac
     8101 caccgcaaaa atcactgtaa tagcaagtga aatccatgct tctgctcccc ccgcatagcc
     8161 attaatcgtt cgaaacggca taaagaaggt cgaaataaag ggaatataag aaccaatctt
     8221 caagaggaga ttgtcaccag ctgcacctag agctgtcact ccaaaaaaac cacccataat
     8281 caaaatcatc aaaggcgaca aggctttccc tgagtcctca ggacgagaaa ccatagatcc
     8341 taggaaggct gccaagacta catacatgaa aagactgatc aaaataaaga gcaaggtatt
     8401 cagtgagata gcatctccca agtgatccaa aataccagac tgagccaaga atggcaaatc
     8461 tttaaagagc aaaacggcag ccagaccacc tacaacatag atcccaatat gcgttaaaat
     8521 cactagaaac agagccatca tccgcgcata gaaatagtga cttgccctta tgctagaaaa
     8581 aacgacttcc ataattttgg tgcctttttc actggcaact tcctgagctg ttacacccgc
     8641 ataggtaatc agaatcatat aaagaaagaa tcctaaggca cctgctgcaa ttgtttgaat
     8701 aaacttttta ttttccttgg cttcatcaat cttttctgtg aattgaattg tctgcgctaa
     8761 gcgtttttcc tgctcttgag acaaggaagc agttgaacga ttaagctgat tttgcagttc
     8821 attgagtgta cctgtaacct caaatttaat tccattttca agcgatgttt cgccatgata
     8881 aactgccttt agaacactat cttcttgatc aatggtcaaa taacctttta atttttcttc
     8941 tttaattgct tctttggcac ttgcttcgtc tttatagtcg aagttaacac catttacatt
     9001 cttcagtcct tctgctacag atggcactgt tgtcactact gccactttat tatttttagc
     9061 catagaagaa ccttggatat gcccaattcc tacagagatt cctaaaaaga ggaacggcga
     9121 aatcaccata aagaagaaac tccatgactt gacatgtcga agataggttt ccttgattac
     9181 aacccacata tttctcatac ttccactcct gattctagtt taaagatttc atcgatagtt
     9241 ggcgcttgtt ggtcaaatgt tgcgatatat tgaccttgag tcaagattgg gaagagttcc
     9301 cttccagcgc tctcatcctc caaaatcaat ttccaactgc cttgtttggt caagctcacc
     9361 tgtttgacat gaggaagatt ttccaattct tccttgcttc gttcacttga aacaaagaga
     9421 cgcgttttcc cgtattgatt gcggacatcc tgaactggtc cgtgcaagac cacacggcca
     9481 tctcggatca tcagaatatc gtcacaaagt tcctcaacat tggtcatgac atggtcagaa
     9541 aagataatgg ttgctccgcg ctctttttcc tgaaaaatga cttgtttgag caattctgta
     9601 ttaactgggt ccaatccact aaaaggctca tccaagataa tcaggtctgg ttcatgaatc
     9661 agagtaataa tgagctgaat cttctgctga tttccttttg acagactctt gattttatct
     9721 gtcagctttc ctttcacttc caacctcttc atccattgag ggagtttttc tttgacttct
     9781 ttggcatcca tgccttttag agtcgccaag tagcgaactt gttcaagaac tgtcaattta
     9841 ggcatgagac tgcgttcttc aggcagataa ccaatccgag cataggtctc ctgacgaata
     9901 tcctgaccat ccagaccgat ttctccctga tattctagga atttcaaaat actatggaaa
     9961 atcgttgttt ttccagcacc attttttccg actagtccca aaatacgacc tggtcgcgct
    10021 tgaaagtcaa taccaaacaa aacttgcttg gatccaaaac ttttctctag acttcttact
    10081 tctagcatct ttcacctccg aaatttcttg cactcattat actccttttt gatagccttt
    10141 acaatgtttt ttgtccattt ttagaagact attgctgtgt aaaatatggc ctggagcact
    10201 tttatactca atgaaaagca aagagcaaac taggaagcta gccgtaggct gctcaaagta
    10261 cagctttgag gttgcagata aaactgacga agtcagctca aaacactgtt ttgaggttgt
    10321 ggatagaact gacgaagtca gtaactatat ctacggcaag gcgaagctga cgtggtttga
    10381 agagattttc gaagagtatt agtgataaat ccattataca gtagcaaact taatttatac
    10441 cttccgctcc tcaactgtct atttttaatc ctgaattgtt atttgagtaa ctcctttttc
    10501 ctcataaagt tttcttcctc taaaacttct ggaaaaaagc gaatagtttc agacaacatt
    10561 tttataagaa acaagttcat ctgtcatttc aagaaggagt aatcctttat ctactaatgg
    10621 acggaacgga attcaaccgc ttgtccgata tgttttctaa ggattatata gtaaaatgaa
    10681 ataaaaacat gacaaataga tcgggacagt caaatcgatt tctaacaatg ttttagaagt
    10741 agatgcgtac tattctagtt tcaatctatt atatctatta tgcacaccac tataggatct
    10801 aataaaaatc acaacaagtt cattcataga tggttacctc agggaactaa gaaaacgact
    10861 acaaaggaag tcgcattcat cgaaaagtgg attaacaact atcctaaaaa atgcttgaac
    10921 tacaagtccc ccagagaaga cttctggatg actaacttga acttgaaatt tagcaataat
    10981 taattcacca tctaactata tttagtaatt atttcagaac tgattaatat taaaattaac
    11041 taacaattca aaggattcat actagccata aattacgtcc atcagagaga gactcttact
    11101 acttttagat tttagtcttt ctagcttcag aatacatcta aactttaggg aaaatgacta
    11161 tttgaaagcg cgaatgcctc aaaattatct cagataagct attcgaaact tagaatgctt
    11221 ttaaatttat ggaattgcga ttattcgaaa cctagaatgc atataacctt tagttgacag
    11281 acctattcta agtctcgaag ggctatttac tttctattcc ttatcaaaaa agactcattc
    11341 cccctttctc ctccaaaata tggtatagta gaaatatact atctatgagg agtttacatg
    11401 tcacaggata aacaaatgaa agctgtttct ccccttctgc agcgagttat caatatctca
    11461 tcgattgtcg gtggggttgg gagtttgatt ttctgtattt gggcttatca ggctgggatt
    11521 ttacaatcca aggaaaccct ctctgccttt atccagcagg caggcatctg gggtccacct
    11581 ctctttatct ttttacagat tttacagact gtcgtcccta tcattccagg ggccttgacc
    11641 tcggtggctg gggtctttat ctacgggcac atcatcggga ctatctacaa ctatatcggc
    11701 atcgtgattg gctgtgccat tatcttttat ctagtgcgcc tatacggagc tgcctttgtc
    11761 cagtctgtcg tcagcaagcg cacctacgac aagtacatcg gctggctaga taagggcaat
    11821 cgttttgacc gcttctttat ttttatgatg atttggccca ttagcccagc tgactttctc
    11881 tgtatgctgg ctgccctgac caagatgagt ttcaagcgct acatgaccat catcattctg
    11941 accaaaccct ttaccctcgt ggtttatacc tacggtctga cctatattat tgactttttc
    12001 tggcaaatgc tttgacacgt aaaaaatccg tttggtttcc caagcggatt ttgtgcttta
    12061 ttttgaaact tcttttgcaa gaacaaagtt cccaagtgtg gcagaaccat ttcctgcgac
    12121 tgctggcgtc acgatatagt cacgcacatc tggtactggt aggtaaccat taagaagaga
    12181 tgtaaatttc tcacggacac ggtccagcat atgttgttga gccatgaccc ctccaccaaa
    12241 gacaatcacg tctgggcgga aagtcactgt cgcattaacc gcagcttgag cgatatagta
    12301 ggcttgaaca tcccaaacag ggttgttgaa ttcaatagtt tccccacgta cacctgtacg
    12361 agcttccaaa cttggaccag ctgcataacc ttctagacat cccttatgga aaggacaaac
    12421 acccttaaac tctttttcaa tatccattgg gtgtctagca acataataat gacccatttc
    12481 agggtgaccc acaccaccga taaactcacc acgttggatg acgcctgcac cgatacctgt
    12541 accgattgtg tagtaaacca agttttcgat acgaccacca gcattgttac gggcaaccat
    12601 ttcaccgtaa gcagagctgt ttacgtctgt tgtgaagtac attggcacgt ttagggcgcg
    12661 acgaagggca ccaagcaagt ccacatttgc ccagtttggt tttggagtcg tcgtgataaa
    12721 gccataagtt tttgagtttt tgtcaatatc aatcggccca aatgaaccaa ctgcaagacc
    12781 agcaaggtta tcgaattttg agaagaactc aatggtttta tcgattgttt cgattggagt
    12841 tgttgttgga aattgtgttt tttctacaac gttaaagttt tcatcaccga cagcacagac
    12901 aaactttgta ccgcccgctt ccaagcttcc atataatttt gtcatgataa acctcttgtt
    12961 tttattttct ttattatagc atacttcgaa agtctaaatg tctctatttt ttagattttc
    13021 ctctgtaaat cttactatct aataaaaacg aacaaacatg tcatttgttc gttttcacat
    13081 tagagaggat tgattagatt ttcacttcga tcacagcatc ccccttcgca actgaacctg
    13141 ttgcgactgg agctactgaa gcgtagtcag ctgtatttgt aacgataacc attgttgtat
    13201 catcaagtcc agctgcagcg attttgtttg agtcaaatgt tccaagaaca tcgccagctt
    13261 tcaccttatt accttgagca acttttgctt caaaaccgtc accgttcata gatacagtgt
    13321 caataccaac gtgaatcaaa acttcagcac catttcttgt tttcaaacca aaagcgtgcc
    13381 ctgttggaaa ggcaattgaa acttcagcat cagctggtgc atagaccaca ccttggcttg
    13441 gtttcacagc gataccttgt cccatagctc cacttgagaa gactgggtca ttgacatcag
    13501 caagagcgac aacatcacca acgataggag ttacaagtgt ttcattttga agagctgctg
    13561 gcgcaacttc ttctttttct tcagccactt cagcttgttt tgcagctgca gttgcgtcta
    13621 cttcatcttc gtaaccaaac atgtaagtaa gagcaaaacc aagggcaaat gatacagcta
    13681 ccataagaag gtattgtgga agttgtccgt taccaacata aagcattgta ccagggatga
    13741 tggtgatacc attaccagta ccagcaagtc caaggataga agccaatcca ccaccgattg
    13801 caccagcaat caatgaaagg aagaatggtt tacggaagcg caagttcacc ccgaagatag
    13861 caggctctgt aatacctagg aaggcagaaa gagcagccgg gaaagcaagt gttttcagtt
    13921 ttggattttt tgttttaaca ccaaccgcaa cagtagcagc accttgagct gtcatagcag
    13981 ctgtgatgat agcgttgaat gggttagcat ggtcagcagc aagtaattgc acttcaagca
    14041 agttgaagat gtggtgcaca cctgacacga cgatcaattg gtgaacccca ccaatcaaga
    14101 aaccaccaag accaaatgga atgctaagaa tcgcttttgt agcaataagg atgtagtttt
    14161 caacaacgtg gaaaactggt ccaatgacaa agagtccaag gatagacatg accaaaagtg
    14221 tcacgaatgg tgttaccaag aggtcaatga catctggaac aaccttgcgg acagcttttt
    14281 caaatttagc tccgacaacc ccgatgatga aggctggaag aacggaacct tgcaaaccaa
    14341 caacagggat gaaaccaaag aagttcatcg ctgttacttc accaccttga gcaactgccc
    14401 aagcgtttgg aagtgagcca gagacaagca tcataccaag aacgatacca acggcaggat
    14461 ttccaccaaa tacacggaag gttgaccaca caaccaaacc tggcaagatg atgaaggctg
    14521 tatctgtcaa gatttgtgtg taagttgcaa agtcacctgg aagtggcatt tcaagagcgt
    14581 tgaaaagacc acgcacaccc atgaagagac ctgtcgctac gataactggg atgattggaa
    14641 cgaaaacatc accgaaagta cggatagcac gttggaacca gttcccttgt ttagcaactt
    14701 ctgctttcat gtcatcctta gatgatgttg gtaagccaag tacaacaact tcatcgtaca
    14761 ttttgttaac tgtacctgta ccaaagataa tttggtattg ccctgagtta aagaaagcac
    14821 cttgaacttt ttccaagttc tcaatcactt ctttattgat tttctcttca tctttgacca
    14881 tgacacgtag acgagtcgca cagtgggcaa cactattgac attttcacgt ccgcccaagg
    14941 catcgatgac tttttttgca atttcctgat tgttcatttg caaaaatctc cttatataac
    15001 attttgttct tgtttgaaag cgattttatt cgcccttacg actattattt tatcatgttt
    15061 taaaaatatg tcaagcgttt tgcagaaaaa atattctatc cacttagtgg gcaagtttta
    15121 gattgattgt ttttgactgt ttcatcagga attccttgaa aaataagttt gaaaccttgg
    15181 ttaaaaagta ttttatttca ttatctttca cattttcgta aaaatttgat tgatttcctg
    15241 tatttatttc atgataatcg tttgacagtt ttttctcttt tttaatataa aaggcttgca
    15301 ttttttatcg aaaacagtta ctattaaaag tgataagatt tttggaggaa tgaatggaat
    15361 ggacaactga gcgtcgttac agactttatc aagattggac gcaagaagaa attcaacata
    15421 taaaggaaaa tatggcacaa tctccatggc atactcatta ccatgttgag ccaaaaacag
    15481 gacttctcaa cgacccaaat ggcttttctt acttcgatgg caagtggatc ctcttttacc
    15541 agaattttcc ttttggtgca gcccacggtt taaaatcttg ggcacagcta gaaagtgatg
    15601 atttggttca ctttagagaa actggagtca aagttttgcc agatactcca ttagatagtc
    15661 acggtgccta ctctggttct gccatgcaat ttggcgataa cttattccta ttttatacag
    15721 gaaatgttcg cgatgaaaac tggatccgtc acccatacca aatcggtgct ttgatggaca
    15781 aggagggtaa gattacaaag attgacaaga tcttgattga ccagccagca gactctactg
    15841 accacttccg cgatccacaa atttttaact ttcagggtca atattatgcc attgtcggcg
    15901 gacaagactt ggagaaaaaa ggtttcgttc gtctctacaa ggctgtcaat aacgactaca
    15961 caaactggca agcagttggc gaccttgact ttgctaacga ccgtactgcc tacatgatgg
    16021 aatgtcctaa tctggtcttt gtagaggaac agcctgtcct tctctactgt ccacaaggat
    16081 tggataagaa agttctagac tacgataata tctttccaaa tatgtataag attggggctt
    16141 cctttgaccc taaaaatgcc aaaatggtag atgtgtctca acttcaaaac atggattacg
    16201 gtttcgaagc ctatgcaact caagccttca acgctcctga tgggcgtgct ctagcagtta
    16261 gctggcttgg tttgccagat gtttcttacc catctgaccg ttttgaccac caaggaacct
    16321 tctctttggt caaggaactc actatcaaag acgacaagct ctaccagtat ccagtcgctg
    16381 ctattaagga ccttcgtgct tctgaagaag ccttctcaaa ccgtttccaa accaagaaca
    16441 cttacgaact tgaactcaac ttggaagcta atagccagag cgagattgtc ttacttgctg
    16501 ataaagaagg taagggactt tcaatcaact ttgaccttgt aaacggtcaa gtgacagtgg
    16561 atcgtagcca ggctggagaa cagtatgccc aagaatttgg gacaactcgt tcttgcccta
    16621 tcgagaatca ggctactact gctacaatct tcatcgataa ctctgtcttt gaaattttca
    16681 tcaataaagg agaaaaagta ttttctggtc gtgtcttccc acatgcggac caaaatggta
    16741 tcctgatcaa atctggaaac ccaactggaa cttactatga attagattat ggtcgcaaaa
    16801 ctaactgatg tcgccaaact tgcaggcgtc agtcctacta ccgtttctcg ggttatcaat
    16861 aaaaaagggt atctatctga gaaaaccatc caaaaagtca atgaagccat gcgagaattg
    16921 ggctataaac ccaacaacct ggctcgtagt ctgcaaggaa aatcagctaa gttaatcggc
    16981 ttgattttcc ccaatatttc caatgttttc tatgcagaat tgattgataa attggaacac
    17041 caactcttca aaaatggtta caagaccatc atctgcaaca gtgaacatga ttctgagaag
    17101 gaacgtgaat acatcgaaat gttggaagcc aatcaggtgg acggcatcat ttctggtagt
    17161 cacaacctag gaatcgaaga ctacaatcgt gtgacagcgc cgattatttc ctttgaccga
    17221 aacctatcgc cagacatccc tgtcgtctcc tctgacaact atgctggtgg ggttcttgct
    17281 gcccaaacct tggtcaagac aggtgcccag tctatcatca tgattacagg gaatgacaat
    17341 tccaattcgc caaccggact gcgccacgct ggttttgcat ccgtactccc aaaagctcct
    17401 attatcaatg tttccagtga cttttctccc gtcagaaaag aaatggaaat caagaatatc
    17461 ttgacccggg aaaaaccaga tgccattttt gcttcggatg atttgacagc tattctggtc
    17521 attaaaatcg ctcaagaatt gggcatttct gtcccaaaag agctcaaggt catcggctat
    17581 gatgggacct actttatcga aaattactac cctcaattgg ctactatcaa gcaacctttg
    17641 gaagagattg cttgtctcac tattgatctt ctcttgcaaa agattgaagg caaggaagtc
    17701 gccacaactg gttacttctt accagttacg ctattaccag gaaaaagtat ttaaacacaa
    17761 gaaaactcag accgattcgt ctgagttttt atgatcttaa attttcgaga tagcgctggg
    17821 ctgtctctag gttaaaggtt ttatctgaga tgaggcgctc tactagggga gcaacttcag
    17881 attcactagc cccagctagg agagctaggg atttggcctg tagtttcatg tggccttgct
    17941 ggatgcccgt acttaccaag gctttgaggg ctgcaaaatt ttgagcaaga ccgatggaca
    18001 cgataatctg ggctaattct ctggcagaag gatttcctag tagatcatga ctgagagcta
    18061 cacgtgggtt gaggccgata gagccaccct tagtcgctac aggcatgggc agggtcatct
    18121 caccgaccaa ttcttctctt tcaaggtcca gcgtccagca gctaagacct tgatagcgtc
    18181 catctcgact ggcaaaggca tgggccccag cttcgatggc acgccagtca ttaccagtgg
    18241 caatcaaaat cgcatcaata ccattaaaaa ttcctttatt atgagtagca gctcggtaag
    18301 gatcagcctg cgcaaactga ctagccaacg caattttctc cgcaatctct cgtccttgat
    18361 ccttttggcg gctcaagtag cgaaaggcga tgcgacagct tgcagtcacc agagaatcag
    18421 tcgcgtagtt ggacaggatt cccatgagac tctgtccctg actgagttct tctaagactg
    18481 gtttcaaggc ttccagcatg gtgttgagca tattggcacc catggcttcc tgggtatcga
    18541 catgaatata aacaacgaga aagtctggtt cgccttttat ctgctcgaca tgcagatcac
    18601 gcgccccacc cccacgttta acgatagaag gataggcttg attggcaagc tccaagagct
    18661 ccgctttctt gctggcaatc ttctcttgcg ctagtttagg attagcaatt tgataaaggg
    18721 ctacctgccc aatcatctgg cgctgatgga cttgtgcagt aaaaccacct gcacgcttga
    18781 tgattttgct ggcatagctg gccgccgcaa ccacagaggg ttcttctgtc acatagggaa
    18841 cggtgtattc ctgaccgttg acaagtacct ccggaaccag cgaataaggc agagaaaaag
    18901 ttcccaccac attctcactc agctggtctg ccacagtcac actcatctgt tcatccttct
    18961 ccagactagc ttgtctctca ggactaagga gcgcctgagc ttttagcagc tcgaggcgct
    19021 cttggtatga ttttttagaa aatccattcc aacttatctt cattattttt caaccttgct
    19081 ataacggcgt tggtggtcaa gaatttcaac caaggcaaaa tcttgatttt catagccagc
    19141 aaactgggca gagtttgttt catccaagtt tacttcctca aaaaagacct tttcatagtc
    19201 tgcaacggat agggcagttc gttggttgag cttgttcaag cggtctttat ccaaataagc
    19261 ttcatatcct tcaaccaatt caccactgaa gaactcagcc acagctccac ttccgtaact
    19321 ataaagggcg attttatccc cagctttcaa gctatctgta ttttccaaga gagacaaaag
    19381 tccaaggaaa agtgaacctg tgtagatatt ccccaccttt tgactgtaga gaatagactg
    19441 gtcaaaatgc ttttgtaaga ggtctttttt ctcttgaggc aggctcttat ccatgatttt
    19501 tttcaagcct tttagcgcta atttaggata aggcaagtgg aaacaaacag cagcaaaatc
    19561 atccaaagta agctggtagc gtttttgata ttcaagccaa gtcgttttca aactatccaa
    19621 gtattgttgg gtagaataga caccatttac ataaggagtt gtcgagtaat ttggtcgcca
    19681 gaaatccatg atgtcacggg tctgagctac attgtcatta ttaaaggcca tcatgcgtgg
    19741 attttgtgta atcaacatag ctacacttcc agcaccttga gttggttctc ccggagtttc
    19801 aataccatat ttggcaatat cactggcaat gaccaatacc ttggactccg gagaattttc
    19861 cacatgcaat ttggcataat ggagggcagc tgtcgcccca tagcaggctt ctttaatctc
    19921 gaaactacga gcaaagggct ggatgcccag caagccatgc acaaagacgg ccgcagcctt
    19981 actctggtca attcctgact cggtagccac aatgaccatg tcaacttctt gtctttcttg
    20041 ctcagttaaa atagagtcac tagcactggc cgccaaggtc acgatgtcct cagttagggg
    20101 cgcaatactc aattccttga gtaagagtcc tttacttaat ttttcagggt caattcccct
    20161 cgcttctgct aagtcttgta atttcaagac atattgactg gtcgcaaaac caatcttatc
    20221 aataccgatt gtcatattta cctctgtttt atcattcatg taaaaaatcg ttctatacta
    20281 ttttatcaca aatggcagta aaagagagaa aaaagacttg attcaccaaa tcaagcctct
    20341 tattggtcat cattttaaag aatgattagt tgctagagag ttcaccgata taagtagctt
    20401 tataagctcc attcacagtt atcagctcct ggaggatcaa atttcctgag taagtccttc
    20461 ccatctcatc tacaaatttt tgataaaact gactggtcgg aatttctctg acatccttat
    20521 caaatgtctt gtcaagtgtt ttactaacct tctcagcaat caattgatgc tcttgccatc
    20581 cactttgaaa ctctgagccc gaactagaaa ccatgactgg gataaacaac aaggtcagta
    20641 gacttacaga caataaggaa aatagtagac ttcctgcaaa actagaatcc tagttcatga
    20701 ttgataatac caacaatcaa attcattcgt aatccgaagc gtttacgatg atttcgatag
    20761 gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac tttgcttctc
    20821 tccttagata gcgcatggtt ataggcttta tcttcagcta ttagcggctt gaggttgctg
    20881 gatttacgtg gagtttgtgc ttgaggatat atcttcatgg gcccttgata accactgtca
    20941 gccaagattt taccagcttg tccgatattt ctgcgactca ttttgaacaa cttcatatcg
    21001 tggcaatagt tcaccgcaat attcaaagaa acaattcttt cttggctggt gacaatcgct
    21061 tgaggttcca tagaatgaca tttctatttt accagaataa ttggctagtt gattttttta
    21121 ggacgattta tttttacctc tgttgcatcc acaatcaccg tattctcagc actaagatga
    21181 gtttttgaaa tcgtaacacc actttgaaca agagttactt caacccattg gctccgacgg
    21241 attaagttgc tttcgtggat accaaaatca gccgcaattt cttcataagt tcgatattct
    21301 cgcacatata gaaagcgttg tcaatctatt tgtctcattt ttcagaaaat tcttttattt
    21361 ctgtaaagtc tacgatactc gatgtgtttt tatataatga tagagtctga gaatcactgt
    21421 tccgctagcc attccaatag agattaccag agccaacatg acaaccaagg tcgcacttgc
    21481 cagtgcttta ttatagtccc ctgtcacaaa aaaggcagtt gttcggtagg agagataacc
    21541 tggaaccagc ggtgccaaaa tggccaagat aaagaccaca gcaggtgtct tataaagaat
    21601 acttaaaatc tggctgacac aagaaccaat aatggctgca atgaaggtag ctacaatgac
    21661 attggtcggt tccttgagca agagatagat tagccagaca gtcatgccca aaatccctcc
    21721 aggtaagagc atagaccgtt gcacattgag tacgattaaa aaagtgataa tggcaagaaa
    21781 acttgctact gcttgtaata aaaaggttgt tagtgtcata ttagttcatc aataccaagg
    21841 cgacagaagt tcctgcccct aaagcgaggg taatgagcag ggattcaaac atcttactca
    21901 taccagagtt tatgtggttg gtcataatat cacggaccgc attggtcaag gcaatacctg
    21961 gtacaaacgg catgaccgca ccagctataa tcaaatctgc cgttgaagga aaacctgtgt
    22021 agcgagccca aaactgggca attatcccaa agacaaaggc tccagcaaag gctgtcacaa
    22081 agggaattcg gataaatttt tccacataga gggaaaaggc aaaaccaaat aaggtcgcca
    22141 ctcctgcccc aagtgcgtcg tagatatttc cgctaaacat aactgaaaag aaaggagcac
    22201 taaaggtcgc agccagagtt acctgcaact tagtataggg aaggggttga gcttgcaagg
    22261 ccgtcaattg cttaaaggct gtttctaagt caatctgccc cccaactagc tgacgagaaa
    22321 tctggttcac atcgcagact ttttcgatgt tataagaaga ggaggtcacg cgcttcatgc
    22381 gcgaaatatt ggtattttca atagagaaaa agatagcggc aggcatggca aggacattgc
    22441 aatccacaat cccctgcgaa tgcgcgattc gaatcatggt atcttctaca cgatggattt
    22501 ctgagccact tttaaggaga atagtccccg ctagcataat cacatcaatg acggcattta
    22561 attcttttga ttcttccatg ctttcctcct tttatcaact ccctctattc tatcacaaat
    22621 ctggactcaa aaaaaatctt tgccatgaaa tcatgacaaa gattgattac tcattttgat
    22681 tatccatctg cttttaagga gtagctgaag ttgttttagg tttgtagatt gaaatcttga
    22741 ctctagtctt atttaggtct accttttcac ctgctctagg actttgttca acaaccatgc
    22801 cttctacact acctgcaggc gctgtcgtca cttctacaac ttctatatta gcttccttaa
    22861 tcccaacaat ttgaatcaaa ttgttcttag taaactccaa gctggaacca atgtaactcg
    22921 gcatggcaac acttgtaact tttttagcta ctgtcaagac aatttgagta ggtttactca
    22981 catcataagt cgttccggca cctggacttt gtttcataat cgttcctggt tcgctttcgc
    23041 tggactcttc ttcctctatc ttaatcaaat tctcaggaac cttcttctgc ttgagttctg
    23101 agattacttc tgtagagttc cgtccaatat agttccctaa ttgaatcgtc gtagcttttt
    23161 tagctactgt caaaacaatt tgagttgcct tgctcaagtc ataggtcgta ccttctggta
    23221 gactttgctt caggaccgtt ccagcctcac tctcattcga ctcttcttcc tcaattttaa
    23281 tcaaattatc tggaactttt ttctctttta attccgcgat aacatcagaa gatttccggc
    23341 cgacataatt actaatttgg aaggattgtt tgcctgatga gacaaccaga ttgattttcg
    23401 ttccttcttt tcgaccagtt ccagcgccag gatctgtacg gataatccgc ccttcttcca
    23461 ccttttcact agcctctgtc ttctcctcac caatctcaaa attggctttt ttgagcgttg
    23521 ccttggcctc tgcaactgtc tgacctgcca catctggaat ggcaatggtt gcaggagttc
    23581 tggatagtat ccaaataaga gaagctgcca ccaatacaag gctggccaac aaaatcaggt
    23641 aacgcatctt aaatctatgt tttttcggtg cttgtggttg gtaagtttcc tctgtcacag
    23701 cctggcttgg gtttttgatt gatttgtgtt ctgtctgcgc ttgaacctta ggaatagatg
    23761 tcaaggtact ctgagaaacc ttcggcaagg tcttggtatc tgccttgctc gtttcatcaa
    23821 agattaactt actttcattt ctacgattgt aggacaagct actagacaag tccacataca
    23881 tctctgaaac cgagcggtag cgattggtca actttttagc agttgccttg ataataacat
    23941 tttctaaagc ctgaggtaca gatggatttt ctgcaataac ggacggcagg ggtttctgga
    24001 aatgctggag ggcaatggtc accgcgctat ccccgtcata agggatatgg cctgtcaaca
    24061 tctcatagaa aataatcccc atggcataga tatcactctg cacagtcgcc ttcgaaccac
    24121 gcgcctgctc tggtgacaag taatgaactg agcccaacat cgagttagtc tgggtcagac
    24181 ttgtctctgc aaaggctaca gcaatcccaa agtctgtgac cttggccgtc ccatctggtg
    24241 tcaaaaggat attttgaggt ttcaagtccc tgtgaacaat tcctcgagta tgggccaagc
    24301 gcatagccaa gagaatttgt cccatgatac ggactgcttc ttcattagaa agaggataat
    24361 gttccttgat atagcgtttg aggtctagtc cagcaacata ctccattgca agatactgtt
    24421 gaccgtcttc ctcgccaata tctgttatcc gaacgatatg aggatggtct agatctgcca
    24481 tagctctcgc ttcacgctga aaacgagcta cagctatcgg gtccgtctgg tagttggtcc
    24541 tcagaacctt cactgccact tcttccccat ctaagattaa gtctttggct aggtagacat
    24601 ccgccatgcc tcctcgacca atctgtttga caatccgata gcgtccggca aaaatcttgc
    24661 cgatttggat cattcttcat cctcctcgtt catagaaaca agggcaaccg taatgttgtc
    24721 taaacctcct gcattgttag caaaacgaac aagtgtctcc gttttatctg ctaaaggaat
    24781 atcactggtt acaatatcac gaatctcact gcctgaaatc atgttggtca agccgtcact
    24841 attgagcaag agatagtcac ctgactcaag gataactgtc ccaaaatcag gctgaatttc
    24901 atctttttgc ccaatagact gggtgataat atttttttgc ggatgagctt ctgcctcttc
    24961 tggtgtcaat tgaccagcct tgagcaattc attaaccaag gaatgatcgc tcgtcaactg
    25021 atggtattct tctccacgaa tcaagccgat acgcgaatca ccaatatgag catagatagc
    25081 ctgattatca ataatagcaa ggacttccaa agtagttccc atgcctctgt aagcttcatc
    25141 ctgaccaagc tggtgaatct tttgattttc aatttctagg taatgggcga accattcacg
    25201 cacttcattg actgtatcga tctgggtatc aacccaagct acacccaggt ctgtgaccgc
    25261 catttcacta gcgatattcc ctgcacgatg acctcccatc ccatcagcta aaataatcat
    25321 ggtacgtcca gctctattga catagtggtt gacatagtct tggttatttg ttcgtttctg
    25381 accaacatct gttaataatg aaatttccat gtgtcagttc cttcctaatc cgatatcttg
    25441 cgaaattgac tgatgaagaa tccatcactt ccatacaatt caggtgtaat gaggatacag
    25501 ccgtctttca tgatatcctt acattcatgt tctagtttta cctgctcgaa ctcgggatga
    25561 ctctctaaaa aggccttaac gacttgaaaa ttctcctctg agacgatagt gcaggtgcta
    25621 taagttatta taccaccttt gcctagtatt tgacaaacac tacctaatat ttctaactga
    25681 atttcctgca aggacgcgaa atctgccgtt tctttattgt atttgatatc tggttttcgg
    25741 cgcaaaagac cgattcctga acaaggagca tccaccaaaa tcttatcaaa ggaatcctgg
    25801 tcaaaaaact catgcacctt tctggcatcc aatttttgag tttgaacccg atctgcaact
    25861 cccagacgtt gggcattttc ttgaattaaa tccaacttgt ggtcgtacaa gtccagagca
    25921 gtaacctgac ctgtcgtaag ataagaggct atatgggctg ttttcccacc tggagccgca
    25981 caggcatcaa gcactcgctc atcaccttgt aaatcaagcg tcggagcaac cagctgactg
    26041 gactcgtctt ggatggtaat ggctccatcc gcaaacaaat tatgccctgc aaaatgccct
    26101 tgctccttaa ccagaccagt ggttgctaaa agggaatcat tcgcctccaa caaggcttgg
    26161 atttcctctt ttcgacttag gtctgttaca cgaatactgg ctttgtttcg cactaacagg
    26221 ctttcaaaga tggcttttgc tctctcctct ccgtattctt ccttgagttt ggtaactagc
    26281 caaactggga gagaataggc aatggagtca cgcttgtttt ttcgcttgat gctagcaata
    26341 tctggccagc cttcacgcaa gatacggcga aggacagcgt tgaccaattt ttcactgcct
    26401 tttttacgga gtttggccaa ttccactgct tcattgacca cagcatgatc tggaatcttg
    26461 tccaaatagc ggagttggta ggcactcatg agaagaagga catagagcca gctgtctaac
    26521 tggtctctgt cttcgataaa gtgggataag taccattcca gagtcagttt acgggctacc
    26581 gttccataga ctagctcggt cactaagccc ttgtctgctg cagagagctg actccccttg
    26641 aggtgtttat ttaaggcaat atttgaatat gcttgattca caaaaacatc ctctagcact
    26701 gctagagcta aacttctagc cgtttctact ttagtcacca aatcgttctc ctacagtcaa
    26761 tgtacgtcca actccgttga ggaaggaagc aatgtccatc ttaggcttac cagctggctg
    26821 cacttgtttg agggatagag ccccttcagc cgttgcgaca atcaattctt tcttgccgat
    26881 agagagaatc tcacctggat ttccctgatc ttctactggt agggcttcat aaatcttaaa
    26941 gcggtcgccc ttaaggaaag tatgggcaac aggccagggg ttcattccac gaatttggtt
    27001 aaagagttga cgattggttt tgttccagtc cagtttttct tcctctggct ttatatttgg
    27061 agagaaggta acctgactcg tatcctgcgg ttcaggtttg atatcaccag caatataggc
    27121 aggcagagtg tccaaaagca aatcacgacc aactagcgcc aatttttcaa acaaggtgcc
    27181 aacattgtcc tcatctgtga tcggaatgct gcgacgaaaa atcatatctc ctgcatccat
    27241 ttccttaacc atttccatga tggtcacacc agcttcctca tccccttgaa tcaaggcata
    27301 atggataggc gcaccaccac ggtgtctagg aaggagggag gcatgaacgt tgacagcaaa
    27361 gtccatgcta tcaaggagtt tgcttgggag aaactgccca aaagcagcag tcacaattcc
    27421 atctgctcct agcttcataa gttcttccat ctctggactt ccagataatt tttcaggttg
    27481 gtagatagat agtcctgctt ccttggcagc ctgcttgact ggggtttctt ggataacttt
    27541 tttacgacca acagcacggt ctggctgggt cacaacggct agaatttcgt aacggtcatc
    27601 tgtcaaaagt ccttttaaga ctgttgctga aaagtcgggg gtccccataa agattagttt
    27661 tgtcatatct tctccttctt ataaaaattg ctgcggctca tggtcaatgc tgagacggag
    27721 ctcactattt tcccgttctt gagtcaaggc taaaacctgg ttgagggtcg gccccagctc
    27781 atcttctaaa cggtatttaa ttaaaatctg gtaatgatag aggttgtggg tacgggcaat
    27841 cggttttggc gttggcccca gaatgggact ggtctctgac aagcctgacc gcaaaatgtt
    27901 catgacttca taggcacgtt tgaaaacctc ttcttctttc ttgtgagaaa gggtaatacc
    27961 aatcgtgaaa tagtaaggtg gatagccgag ttgtcgtctg attcccattt cataggcata
    28021 aaagccttcg taatcttgat ccttggcaaa tcgaatagca tagtgctgcg gattgtagga
    28081 ctgtatcaag acttgacctg ccttttcagc ccgacctgat cgacctgcca cctgagtcaa
    28141 gagctggaag gttctctcag aagaacggaa atcaggcaga ttcaaggccg tatccgcatt
    28201 tagaactccg actagggtaa cattgggaaa atccaaaccc tttgcaatca tctgagtacc
    28261 aagtaaaata tccgcttccc ctcgcccaaa ctggtcaagc aaggcttggt gactgccttt
    28321 ctttcgagtc gtatccacat ccatcctcag aatgcgagct tggggaaaga gttctgctag
    28381 ctcatcataa gccttctgag ttcccgttcc atagtaacga atactgtggc tcttacagtt
    28441 aggacagacc tgaggaatat ccttcgagaa accacaataa tggcagttca tagtcttggt
    28501 atccatatgc aaggtcagag aaatatcgca gttgggacaa gtatccaccg tcccacactc
    28561 ccgacacatg acaaagctag aataaccacg gcgattgagc atgagaacca cctgctcttt
    28621 tttaaccaga cggtcttgga tagcctctag caaaggaggc gtaaagtttg acgtctcatt
    28681 ttgtccgata tagtctcgaa agtcaatcac ttgaacctca gggattgtag ccaaaggatt
    28741 ggcacgttgg gttagacgta agtgttgata gacgcctttg ccagcacgtg cccggctctc
    28801 taagctcggc gttgcagatc caagtaccag agttgcttga ttatactgag cccgtaaaat
    28861 agctacctct ctggcatggt aacggggatt gctgtcctgc ttataagccg cttcatgctc
    28921 ttcatcaata atcatgacac ccagattttt cagaggagca aagatagcag atctggcacc
    28981 aacaacaact tgggcatcgc cacgctccac cttgcgccat tcatcatact tttcgccatt
    29041 ggataatcct gagtgaagaa tggctacctt gtccccaaaa cgtgctataa aacgctcggt
    29101 catctgagga gtcaaggaaa tctcaggtac cagcaaaata gctgtcttgc ccttatccag
    29161 ggcaccttgg ataatctgca agtaaacctc ggtcttccca cttcctgtaa tcccttgaag
    29221 tagaaaggga ggttgagaac tgccaataga actcacaacc gcatcacgcg cctgtctttg
    29281 ttctggattt aactccaaag gtctacttgc ttcaattcct tcaaaataag cagccgagcg
    29341 ttgaacttcc ttttggacta tggtaacagc accttgatcc acaaagaagt tgacttgctc
    29401 tcgcgagtag gactctaaca agctagccaa ggaagcgctc tctggatgag acagcagata
    29461 atctctcagt tccaactttt tcttggcacg tgtagaaatc tcaacacctt ctaattgggc
    29521 atggtcaacc tcataccaag actgggtctt gaccttcttt tgatcgactg cctgatattc
    29581 cagaccaagc aggccttttc tagtcaaacg catcatttca gcttgcttac ctaaatccag
    29641 agaagaaaag gctagcgaat cttctgaatc aaacaggcgt actcgttctt cctgactcaa
    29701 gccttccaga ggatagagaa tcttgtcata gctagaattc agaaatcccg gaagcatggc
    29761 cttgaggata gagattttgt aggagaagac agatttgcgt aactcctcag ccagccagag
    29821 ttgttctggc gtgagaacag gagaaaaatc cagcacctct gcaatatctt ttaaatcttg
    29881 ctccatctct tctccatctg attgggactc caaaccaaga acaatccctt gaatcaggcg
    29941 attaccctta ccaaaaggca catgaacccg catcccaact tccagcattc cctcaaattc
    30001 ctccggaatc ctgtaactat agggctggtc cgtctgcatc aagggcacat ctacgataat
    30061 cttagctagg gccatcttct cacctcctcc ttgtcagtac attcttgcaa tagaaaaaat
    30121 aagattgagt ccccccaacc ttaaattttt tcaccatctt ctttttcttt agcaatttgc
    30181 tctttgattt tcttttcttc ttcttctttg cggcgttttt cttcttcgat acggcgacgc
    30241 actgcttcac gttttccttc tggatctggg tgaattgtaa cgtttcctga ttcgatttct
    30301 tctaaagcgc gaagagttga tttttcagac ttgaaacctt gagttgctgg ggcacctgct
    30361 tccaattcgt gggcacgttt tgcttccaag attacgagtg aatattttga aggaaccttg
    30421 tcgagcaagg tatcaataga gggttttaac atcatttgct tgtacctatt ttctaaattt
    30481 tatcgggtag ttggagattt tggtaacatc tcctgatagt gaccaatgac acgatccaca
    30541 cagaagtgtt ctgcttcaat cacacatttg acacgttcag cagctagggg cacctgatcg
    30601 ttgacaatcg cataatcata ctcacgcatg agggcaattt cttccttggc cttttcgatt
    30661 cgttgggcaa tcacttctgc actatctgtt ccacgaccta ccaagcgatc ttgcaattca
    30721 tccaaatctg gtggtgtcag gaagataaag acagcatctg gaaccttttt cttgacctga
    30781 agagcaccct gaacttcaat ttcaaggaaa acatcgattc ccttgtccaa ggtttcattg
    30841 acataggtca gaggagttcc atagtagttg ccgacatatt ctgcgtattc caacatttgt
    30901 ccttgacgaa tcagctcttc aaattcttca cgagtacgga agaaatagtc aacaccgtcc
    30961 acttctccag gacgttgtgc gcgtgtcgtc atcgatacag aatattgaaa ttggttttca
    31021 gaactctcaa aaatctctct tctaaccgtt ccttttccaa cccctgaagg accagaaaaa
    31081 acgattagta agcctcggtc tgccattgtg tctcctttta gtcaatctgt gaaataacat
    31141 ttctctagaa taatggcaaa aagccagatt atcctttaca gtctttctat ctagtgtaac
    31201 aaaaaagcag taatttttca actgctcttt cttatttatt tagcataatc tactgcacga
    31261 agctcgcgaa tcacggttac cttgatattt cctggataat cgagattgtt ttcaattttc
    31321 ttacgaactt tgtgagccaa gattgtgact ttgtcgtcct tgatttttcc tggattgacc
    31381 atgatacgaa tttcacgtcc tgcttgaagg gcaaagctag tttgcactcc ttcaaagccg
    31441 ttagcaattt cttccaaatc atggagacgc ttgatgtagc tttcaagaga ctcactacga
    31501 gcacctggac gggctgcgct caaggcatct gctgcagcga cgataactgc tatcacgctc
    31561 tcagcttcaa catctccgtg gtgactagca atcgtattca ccacaactgg gggttccttg
    31621 tacttacggg ccaattccat accgatttca acgtggctac cttcaacctc atggtcaatg
    31681 gctttcccga tatcgtgaag gaatccagca cgacgggcaa gagccgcatt ttcaccaagt
    31741 tcgctcgcca tgataccagc caacttagcc acctcaatcg aatggcgcaa aacattttgt
    31801 ccatatgaag tacggaactg caaacgtccc ataatcttca tcaagtctgg atgaaggttt
    31861 ggcgcaccaa tttcataggc agcagcctca ccgtattcac gaatcttatt gtcaatctct
    31921 tgacggtttt tctcaaccaa ctcttcgata cgagctggat gtatacgacc atctttgagc
    31981 aacatttcca tagtcatacg ggcaatctca cgacgaatcg gatcaaatcc tgacaaggtc
    32041 accacttctg gtgtatcgtc gataatcaca tcgacccctg tcaaactttc aaaggtacga
    32101 atgttacgac cttcacgacc aataatgcgt cccttcatag tatcgtctgg cagatgaact
    32161 gttgagtttg ttgactccgc tacatattca ccagcgatac gttgcatagc ttgaaccaag
    32221 atgtccttgg ccattttgtc agaacgttcc ttgacctctt gctcagcttc gcgaatgcga
    32281 ctggcaatct ccctggtcaa gttttcctct gtctgaacca agataatatc tcgtgcttct
    32341 gcctgagaca gagcaccaat acgctctagt tctgcttctt tttgtctttc gacttcctct
    32401 aattgctctt cacgcgcatc aaggtttttc gctctatcag aaatactttg ttctttttgt
    32461 tcaagtgttt gttctttact cgtcaaattg tcgtccttac ggtcaaggct agtagctctc
    32521 tctgtcaaac gactttcgat ttgtttgagt tcttgacgtt ctgatttgaa ttcagcgtcc
    32581 acttcttcac ggtattttct ggcttcttct ttggcctcca atagtgcttc ttttttaaga
    32641 gacttgcttt cacgtttggc ttcattaaca agtaaatccg cttcacgctc agcttgtcca
    32701 cgtaaattag ttgcttcttg ttcagcattt aaaagcatca actctgcagc ttcctgagat
    32761 gatttcatct tagctgagat gctgacatat ccaatgacta aaccaatgat gacggcaaaa
    32821 acagcaatcg caagcgacat gatttccatg tttttacctc attttattgt tattccgaat
    32881 gacatacatt cttttacatt ctaccataaa aaagtgattt tcacaaacct aaaatagaat
    32941 atgttttggg gaaattagtc tgaattttag gattacactt ccttggtttt ttaaggagat
    33001 aagtcagtgc cgctatcaaa aagttccacc gaatttctac cgctatggat tttctattgt
    33061 tgtgccaaat agtgttccac tagattcaaa cattttgctt tcaagtcttt gaaaattcac
    33121 tttaggaaat cacagcttat cttcaagatc aaatttgtca taaattaact tttttattta
    33181 gttgtatcaa tttat
//
LOCUS       DAVKZI010000023        32655 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKZI010000023 DAVKZI010000000
VERSION     DAVKZI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.023"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..1007
                     /locus_tag="VXB18_001247"
                     /pseudo
     CDS             1..1007
                     /locus_tag="VXB18_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1050..1691)
                     /gene="plsY"
                     /locus_tag="VXB18_001248"
     CDS             complement(1050..1691)
                     /gene="plsY"
                     /locus_tag="VXB18_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0382452.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDYLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1827..3770
                     /gene="parE"
                     /locus_tag="VXB18_001249"
     CDS             1827..3770
                     /gene="parE"
                     /locus_tag="VXB18_001249"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0382453.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            4190..6661
                     /gene="parC"
                     /locus_tag="VXB18_001250"
     CDS             4190..6661
                     /gene="parC"
                     /locus_tag="VXB18_001250"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0382454.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDVAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6793..7815
                     /locus_tag="VXB18_001251"
     CDS             6793..7815
                     /locus_tag="VXB18_001251"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0382455.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7871..8575
                     /locus_tag="VXB18_001252"
     CDS             7871..8575
                     /locus_tag="VXB18_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0382456.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8640..9329
                     /locus_tag="VXB18_001253"
     CDS             8640..9329
                     /locus_tag="VXB18_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0382457.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9326..10249
                     /locus_tag="VXB18_001254"
     CDS             9326..10249
                     /locus_tag="VXB18_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0382458.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10264..10908
                     /gene="pcp"
                     /locus_tag="VXB18_001255"
     CDS             10264..10908
                     /gene="pcp"
                     /locus_tag="VXB18_001255"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0382459.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            11076..11306
                     /locus_tag="VXB18_001256"
     CDS             11076..11306
                     /locus_tag="VXB18_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0382460.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11356..11436
                     /locus_tag="VXB18_001257"
     tRNA            11356..11436
                     /locus_tag="VXB18_001257"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11390..11392,aa:Tyr,seq:gta)
     gene            11446..11517
                     /locus_tag="VXB18_001258"
     tRNA            11446..11517
                     /locus_tag="VXB18_001258"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11478..11480,aa:Gln,seq:ttg)
     gene            11679..12881
                     /gene="rpsA"
                     /locus_tag="VXB18_001259"
     CDS             11679..12881
                     /gene="rpsA"
                     /locus_tag="VXB18_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0382461.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(12966..14268)
                     /locus_tag="VXB18_001260"
                     /pseudo
     CDS             complement(12966..14268)
                     /locus_tag="VXB18_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14461..14958
                     /locus_tag="VXB18_001261"
     CDS             14461..14958
                     /locus_tag="VXB18_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0382462.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            14958..16613
                     /gene="dnaX"
                     /locus_tag="VXB18_001262"
     CDS             14958..16613
                     /gene="dnaX"
                     /locus_tag="VXB18_001262"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0382463.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            16641..16835
                     /locus_tag="VXB18_001263"
     CDS             16641..16835
                     /locus_tag="VXB18_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0382464.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            16985..17755
                     /gene="sufC"
                     /locus_tag="VXB18_001264"
     CDS             16985..17755
                     /gene="sufC"
                     /locus_tag="VXB18_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0382465.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            17783..19045
                     /gene="sufD"
                     /locus_tag="VXB18_001265"
     CDS             17783..19045
                     /gene="sufD"
                     /locus_tag="VXB18_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0382466.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            19056..20282
                     /locus_tag="VXB18_001266"
     CDS             19056..20282
                     /locus_tag="VXB18_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0382467.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            20269..20709
                     /locus_tag="VXB18_001267"
     CDS             20269..20709
                     /locus_tag="VXB18_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0382468.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20763..22175
                     /gene="sufB"
                     /locus_tag="VXB18_001268"
     CDS             20763..22175
                     /gene="sufB"
                     /locus_tag="VXB18_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0382469.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22406..23647)
                     /locus_tag="VXB18_001269"
     CDS             complement(22406..23647)
                     /locus_tag="VXB18_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0382470.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23750..24859
                     /locus_tag="VXB18_001270"
     CDS             23750..24859
                     /locus_tag="VXB18_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0382471.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            25393..25740
                     /gene="ssrA"
                     /locus_tag="VXB18_001271"
     tmRNA           25393..25740
                     /gene="ssrA"
                     /locus_tag="VXB18_001271"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(25923..26010)
                     /locus_tag="VXB18_001272"
     tRNA            complement(25923..26010)
                     /locus_tag="VXB18_001272"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25974..25976),aa:Ser,seq:gga)
     gene            26172..26912
                     /locus_tag="VXB18_001273"
     CDS             26172..26912
                     /locus_tag="VXB18_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0382472.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            26909..27820
                     /gene="pfkB"
                     /locus_tag="VXB18_001274"
     CDS             26909..27820
                     /gene="pfkB"
                     /locus_tag="VXB18_001274"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0382473.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            27817..29769
                     /locus_tag="VXB18_001275"
     CDS             27817..29769
                     /locus_tag="VXB18_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0382474.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKTVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            29933..32158
                     /locus_tag="VXB18_001276"
     CDS             29933..32158
                     /locus_tag="VXB18_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0382475.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPQLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(32203..32637)
                     /locus_tag="VXB18_001277"
     CDS             complement(32203..32637)
                     /locus_tag="VXB18_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382476.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
BASE COUNT         9829 a         5882 c         7266 g         9678 t
ORIGIN      
        1 cctaaaatgg gacgtaatcc aaaaacgaga cctgaagaga ggacagaatt agaacgtctt
       61 caatcagaaa atgagtacct gagagcggag aatgccatcc taaaaaagtt aagagaactc
      121 cgattgaagg aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa ttaatgactg
      181 agttttcgtt agatcttctt ctaaaatcca ttaaactagc tcgttcgacc tactactatc
      241 acttgaaaca gctagacaaa acagataagg accaagagct taaagctgaa attcaatcca
      301 tttttatcga acacaaggga aattatgctt atcgctgtat tcatttagaa ctaagaaatc
      361 gtggttatct ggtaaatcat aaaagagttc aaggcttgat aaaagtactc aatttacaag
      421 ctaaaatgcg acagaaacga aaatattctt ctcataaagg agacgttggc aagaaggcag
      481 agaatctcat tcaaggccaa tttgaaggct ctaaaacaat ggaaaagtgc tacacagatg
      541 tgacagaatt tgccattcca gcaagtactc aaaagcttta cttatcacca gttttagatg
      601 gctttaacag cgaaattatt gcttttaatc tttcaacttc gcccaactta gaacaagtga
      661 agagtatgtt agaacaggcc tttacagaga aatactatga gaatatgatt ctccatagtg
      721 accaaggctg gcaataccga cacgattctt atcatcggtt cctagagagt aagggagttc
      781 aagcatccat gtcacgtaag ggtaacagcc cagacaatgg tatgatggag tccttctttg
      841 ggattctgaa atcggaaatg ttttacggtt atgagaagtc gtttcagtcg cttaagcaat
      901 tggaacaagc cattatagac tatattgatt actacaacaa taaacgaatt aaggtaaaac
      961 taaaaggact tagccctgtg caatacagaa ctaaatcctt cggataaatt aattgtctaa
     1021 ctgtttgggg gcagtacaga actggcgttt tattttttag gatcttgatg ggttaggttc
     1081 aatccccaag ggaccaaatt ttcagtttta tttttgatac gagctatatt gtccttatga
     1141 cgaatgataa tcaaactagc aagtgctaag ataatagcga tgaagagata gtcatagtta
     1201 ctcaggataa aaccaaaaag tggaaagagc agaaccccga taacagccgc gatcgatgct
     1261 gtgacactag acagtgaaat catactgcca agatagagag ctccaaagaa gataatcgca
     1321 aggtagagac agaagatagg cgcaaatccg aaaatcactc cagcactggt tgcgacagcc
     1381 ttaccacctt taaatcctgc aaagataggg aaggtatggc cgataacagc caaaagtcca
     1441 aagatgagag gagaaacgcc ttgtagatga aaaataatcg gaagcagcgt tgctagggtt
     1501 cctttgaaaa agtcaatcac aaaggttgcc ataccagctt tcttacctaa aatgcggaag
     1561 gtgttggtcg ttccagtgtt accagaacca tgctcgcgta gattgatttg aaagaatact
     1621 tgtccaatcc agagaccaga tggaatcgaa cccagcagat aggctaggat taataaaact
     1681 attgtaatca tactcctatt atatcatgaa ttgggaaaga aaagcagaga atctctgctg
     1741 aaattgtcac atcggagaaa gaaaaatttt gcaaaatcct tggaaaacct gtagaatagt
     1801 aaagatgaac gaataggagg ttccttgtgt caaaaaagga aatcaatatt aacaattata
     1861 atgatgatgc tattcaggtg ctagaagggt tggatgcggt ccgaaaacgt ccagggatgt
     1921 atattggatc gaccgatggc gctggtcttc atcacctagt ttgggaaatc gttgataatg
     1981 cagtcgatga agccttgtct gggtttggtg atcgtattga tgtaactatc aataaagacg
     2041 gtagtctaac ggttcaagac catggacgtg ggatgccgac aggtatgcac gctatgggaa
     2101 ttccaactgt tgaagttatc tttaccattc ttcatgccgg agggaaattc ggtcaaggtg
     2161 gctataagac atcaggtgga cttcacggag tgggttcttc cgttgttaac gccctttcta
     2221 gctggttaga agttgaaatt acccgtgatg gcgcagttta caagcaacgt tttgaaaatg
     2281 gtggaaaacc tgtcacgact ttgaagaaaa tcggtacagc acccaagtct aaaacaggca
     2341 ccaaagttac ttttatgcct gacgcgacta tcttttctac gacagatttc aagtacaata
     2401 ccatttcaga gcgccttaat gaatcagcct ttctcttgaa aaatgtgacc ttgtctttaa
     2461 cggacaagcg aacagatgaa gcgattgagt tccactatga gaatggagta caagattttg
     2521 tttcttatct caacgaagat aaggaaatct tgacgccagt tctttacttt gaaggggaag
     2581 acaatggttt tcaagtggaa gtagccctcc agtacaatga cggattctca gataacattc
     2641 tatcctttgt caataacgtt cgcaccaagg acggtggaac gcacgagaca ggactcaagt
     2701 ctgccattac caaggtcatg aatgactatg cacgtaaaac aggtcttctc aaggaaaaag
     2761 ataaaaacct tgaaggttca gactatcgtg agggactagc ggccgttctt tctatcttag
     2821 ttcctgaaga acacttgcag tttgaaggac agaccaagga taaactagga agccccctag
     2881 ctcgcccagt tgtggatgga atagtggctg ataagttgac ctttttcctt atggaaaatg
     2941 gggaattagc ttctaacctc atccgcaagg ctatcaaggc ccgtgatgct cgtgaagcag
     3001 cacgtaaggc gcgtgatgag agccgaaatg ggaagaaaaa caagaaagat aagggcttgt
     3061 tgtctgggaa attgacccca gcccaatcta agaatcctgc taagaatgaa ctctatctag
     3121 ttgaggggga ctctgccggt ggttctgcca aacaaggtcg tgaccgcaag ttccaggcta
     3181 ttctacctct tcgtggtaag gttgtcaata cagccaaggc caagatggcg gatatcctca
     3241 aaaatgaaga gatcaatacc atgatttata ccattggtgc gggtgttgga gcagacttct
     3301 ctattgaaga tgccaactat gataagatca ttatcatgac cgatgcggat accgacggtg
     3361 cccatatcca gaccttgctc ttgacatttt tctaccgtta catgcgtccg ctagtcgagg
     3421 caggtcatgt ctatattgcc ctcccacctc tttacaagat gtccaaaggt aaaggcaaga
     3481 aagaagaagt ggcctacgct tggacggacg gagaactaga agaactccgt aaacagttcg
     3541 gtaaaggcgc taccctccaa cgatacaaag gacttggtga gatgaatgcg gaccagctct
     3601 gggaaacaac catgaaccca gaaacacgta ccctcatccg tgtcacaatt gaagatttag
     3661 cgcgcgccga acgccgcgtc aatgttctca tgggagataa ggtagaacca cgccgtaaat
     3721 ggattgaaga taatgtcaag tttacgctag aagaagcgac agtgttttaa tgaaagaaaa
     3781 taatatgtta gtaaactgga aattagagtc ggatgtgaat gactatgtaa aaaagcagtt
     3841 tgaaaatctt ggtttgaaaa aattgcagga ttattaatga agaatcttct atgagtgctt
     3901 atctcaaaga ggcgtttaag ggagcggcta agacacaaac taagactaat tttggaaaac
     3961 cagattttca tattgaaaaa tacaaacagg atagtttggt tacttatcgt aactgaacac
     4021 gggacgaatt cccgtaaaat atcttttact gcataaaaac ctactctaca ttctttgaaa
     4081 ggagttgaac acgccctaga tactgtgtga aaaagataaa ttctcttgtg agtttgctta
     4141 cttcaagaat tttctatttt cacttggtat tttatgggct ttgtatctta tgtctaacat
     4201 tcaaaacatg tccctggagg acatcatggg agagcgcttt ggtcgctact ccaagtacat
     4261 tattcaagac cgggctttgc cagatattcg tgatgggttg aagccggttc agcgccgtat
     4321 tctttattct atgaataagg atagcaatac ttttgacaag agctaccgta agtcggccaa
     4381 gtcagtcggg aacatcatgg ggaatttcca cccacacggg gattcttcta tctatgatgc
     4441 catggttcgt atgtcacaga actggaaaaa tcgtgagatt ctagttgaaa tgcacggtaa
     4501 taacggttct atggacggag atcctcctgc ggctatgcgt tatactgagg cacgtttgtc
     4561 tgaaattgca ggctaccttc ttcaggatat cgagaaaaag acagttcctt ttgcatggaa
     4621 ctttgacgat acggagaaag aaccaacggt cttgccagca gcctttccaa acctcttggt
     4681 caatggttcg actgggattt cggctggtta tgccacagac attcctcccc ataatttagc
     4741 tgaggtcata gatgttgcag tttacatgat tgaccaccca actgcaaaga ttgataaact
     4801 catggaattc ttgcctggac cagacttccc tacaggggct attattcagg gtcgtgatga
     4861 aatcaagaaa gcttatgaga ctgggaaagg gcgcgtggtt gttcgttcca agactgaaat
     4921 tgaaaagcta aaaggtggta aggaacaaat cgttattact gagattcctt atgaaatcaa
     4981 taaggccaat ctagtcaaga aaatcgatga tgttcgtgtt aataacaagg tagctggaat
     5041 tgctgaggtt cgtgatgagt ctgaccgtga tggtcttcgt atcgctatcg aacttaagaa
     5101 agacgctaat actgagcttg ttctcaacta cttatttaag tacaccgacc tacaaatcaa
     5161 ctacaacttt aatatggtgg cgattgacaa tttcacacct cgtcaggttg ggattgttcc
     5221 aatcctgtct agctacatcg ctcaccgtcg agaagtgatt ttggcgcgtt cacgctttga
     5281 caaagaaaag gctgagaaac gtctccatat cgtcgaaggt ttgattcgtg tgatttcgat
     5341 tttggatgaa gtcattgctc ttatccgtgc ttctgagaat aaggcggacg ccaaggaaaa
     5401 cctcaaagtt agctatgatt ttacggaaga acaggctgag gctatcgtaa ctttgcaact
     5461 gtaccgtttg accaataccg atgtggttgt cttgcaggaa gaagaagcag agcttcgtga
     5521 gaagattgct atgctggcgg ctattatcgg tgatgaaagg actatgtaca atctcatgaa
     5581 gaaagaactt cgtgaggtca agaagaaatt tgcaactcct cgtttgagtt ctttagaaga
     5641 tactgcgaaa gcaattgaga ttgatacagc tagtcttatc gctgaggaag atacctacgt
     5701 cagcgtgacc aaggcaggtt acatcaagcg taccagtcca cgttcctttg cggcttccac
     5761 cttggaagaa attggcaagc gtgatgatga ccgtttgatt tttgttcaat ctgccaagac
     5821 aacccagcac ctcttgatgt tcacaagtct tggaaatgtc atctacagac caatccatga
     5881 gttggcagat attcgttgga aggacatcgg agagcatctg agccaaacca tcacaaactt
     5941 tgaaacgaat gaagaaatcc tttatgtgga agtactggat cagtttgacg atgcgacaac
     6001 ctactttgca gcgactcgcc ttggtcaaat caaacgggta gagcgaaaag aatttactcc
     6061 atggcggacc tatagatcta agtctgtcaa gtatgctaag ctcaaagacg atacagatca
     6121 gattgtagca gtggctccga ttaaactaga tgatgttgtc ttggttagtc aaaatggtta
     6181 tgccctgcgt ttcaatatcg aagaggttcc ggttgtcggt gctaaggcag caggtgtcaa
     6241 ggctatgaat ttgaaagaag atgatgtcct ccaatctggc tttatctgta atacttcgtc
     6301 cttctacctc ttgacccagc gtggaagctt gaaacgtgtt tccattgagg aaattctagc
     6361 aaccagccgt gccaaacgag gattacaagt cttgcgtgag ttgaaaaaca aaccgcatcg
     6421 tgtcttcttg gcaggagcag ttgcagagca aggatttgtt ggcgatttct tcagtacgga
     6481 agtggatgtg aacgaccaaa ctctgcttgt ccaatccaat aaaggaacaa tctatgaaag
     6541 ccgattgcaa gacttgaact tgtcagaacg cactagcaat ggaagcttca tttctgacac
     6601 gatttcagat gaagaagttt ttgacgctta tcttcaggaa gtagttactg aagataaata
     6661 agtgaaatga agaatcagtt ctaagagctg gtttttattg gagaaatttt ctgaaaatta
     6721 caaaatatac ttgctatttt agaaaaatag tgtagaatat aagaaatagg tttttagaat
     6781 aaggagtgga atatgacagt aacgattgat tgggaaaacc tcggtttttc ctatatgaaa
     6841 ttaccttatc gctatcttgc tcatttcaaa aatggacaat gggatcaagg agagcttaca
     6901 gaggatgcaa ctttgcatat ttcagagtct tctccaagtc ttcactatgg acaacaagca
     6961 tttgaaggtt tgaaagctta tcgtactaag gatggcagtg ttcaactgtt ccgtcctgat
     7021 gaaaatgcta aacgcctgca acgtacatgt gaccgtctct tgatgccaca agttccgaca
     7081 gacatgtttg tagaagcttg taaagcagtt gtccgtgcga atgaagaata cgtaccacca
     7141 tacggaatag gtggaacctt atatcttcgc cctcttttga ttggtgtcgg agatattatc
     7201 ggggtaaaac cggcagaaga atacattttc accatctttg ctatgccagt tggaaattac
     7261 tttaaaggtg gtttggtccc aaccaacttc ttgattcagg atgagtacga ccgtgcagca
     7321 ccaaatggta caggtgcggc taaggttggt ggaaactatg ctgcaagtct cttaccagga
     7381 aaaatggcca agtcacgtca tttctcagat gttatctatc tggacccatc aactcataca
     7441 aagattgaag aagtcggatc agctaacttc tttggaatta cagctgataa tgaatttgta
     7501 acaccattga gtccatctat cttgccatct attaccaagt attccttgct ttatttggca
     7561 gaacatcgct tgggattaac tcctattgag ggtgatgttc caattgataa tcttgaccgt
     7621 tttgtagagg caggtgcctg tggtacagca gcggttattt ctccaattgg aggtattcaa
     7681 catggtgatg atttccatgt attctatagt gaaacagaag taggtcctgt gacgcgtaaa
     7741 ttatataatg aattgacggg tattcagttt ggcgatattg aagcgccaga aggttggatt
     7801 gtaaaagtag attaaaataa accaaaggag attttttatg aaatagaaaa agtggctctt
     7861 aacagcagga gtggtcctga gcacgtcagc tattttagtg gcttgtggaa aaactgataa
     7921 agaagcagat gcaccgacaa cattttctta tgtctatgca gtagatccag catcattggg
     7981 ctacagtata gcgactcgaa catcgaggac agacgttatt ggaaatgtta ttgatggttt
     8041 gatggaaaat gataaatacg gcaatgttgc tccttctcaa aaagactatg atttgaacag
     8101 tacaggatgg gctccaagct atcaagatcc agcgtcttac ttgaatatta tggatccaaa
     8161 atctggttct gccatgaaac accttggcat tacgaaagga aaagataagg atgttgtagc
     8221 taaacctggt ttggataaat ataagaaatt gttagaagat gctgtttctg agaccactga
     8281 cctagagaag agatatgaaa aatatgccaa agctcaagct tggtcgacag atagttcatt
     8341 attgatgcca acagcttcat ctggtggttc tccagttgta agtaacgtag taccattctc
     8401 aaaaccatac tcacaagttg gtattaaggg ggaaccatat atctttaaag gaatgaaatt
     8461 gcaaaaagat attgttacaa caaaagaata taacgaggtt tttaaaaaat ggcaaaaaga
     8521 aaaattggaa tccaatagca aataccaaaa agaactagaa aaatacatta aataaggaat
     8581 ggtattgatc ttgataaaat ttttaaaata ctgtcatttt gaatataaag gagtttgata
     8641 tggagtggat tagattaata ggaatagcaa tcattgttgt gggttttatt ttaaaatttg
     8701 atacaattgc aacagtagtc ttagctggtt tggttacagc tttagtttca ggtgtttctc
     8761 tcgttgaatt tttggagatt ttgggaaaag aatttagcaa tcagcgagtg ctcacgattt
     8821 ttatggttac cttgcctctt gtggggctgt cagaaacctt tggactcaag caacgatcaa
     8881 tcgatttgat tcgaaagatt aaaggtctga cagttggaaa cttctataca gtttatttct
     8941 ttattcgaga gttagctggt ttcttttcaa ttcgtctagg aggacaccct cagtttgtca
     9001 gacctttggt tcaacctatg ggagaagcag ctgcagagtc tcaattaggt agaaagttaa
     9061 cagaggttga agatgagaca ataaaagcgc gtgcggctgc gaatgaaaat tttggaaatt
     9121 tctttgctca aaatacgttt gtaggtgctg ggggagtcct cttgataggg ggaacattag
     9181 atcagttagg ctatgaaagc aattatgcag ggattgcttc tacatctatt attgttgctg
     9241 ttataacact tattgtagtg gggatttaca attatttatt tgataaaaaa ttgatatcaa
     9301 aaaagactag gggaggagaa caaaaatgac agagttggca aagcaactat tagagttgac
     9361 ctatattgtg attggttgtc aatttctcca tacagcctat tgtagttata aagataaaac
     9421 aaacccagtt cgacttggga catctgcatt ttggactcta ttgtctatta cgtttatagg
     9481 tggttcctat atgccaaata tgagtattgg tattattgta atcctattat cgctgttaac
     9541 attgtttaag caagtccgta tcggaacctt gccatcctta gatgaaatga aagccaatat
     9601 tgaatctaac aggttgaaaa ataaaatttt tattccagtt atgctgatgg caatacttgc
     9661 gttggtctta gcgcaaatga ttccagaatt tagcaagatt tcgattagcc ttgccgcctt
     9721 gtttgctaca atttctgttc ttgtgattac caatagtcac cctaagagtc tgttatcaga
     9781 aaataatcga atgactcagc aagtttcaac aagtgggatt gttcctcaat tattaggggc
     9841 tttgggggct atttttactg tagcaggtgt tggtgatgtt atctctcatc tgattagcgg
     9901 tattgttcct tcagatagtc gctttatagg agttttggct tatgttcttg gaatggttct
     9961 attcacaatg attatgggaa atgcttttgc agcattcacc gttattacag caggtgttgg
    10021 agttcccttt gtatttgctc tgggagctaa tccaattgtg gctggtgctc ttgccatgac
    10081 agcaggttat tgtgggacct tattgacccc aatggctgct aattttaacg ctctaccagc
    10141 agcattgatg gatatgaaag atcagaatgg cgttataaag gctcaagcag gtgttgctct
    10201 agtaatgatt gttattcaca tattcttaat gtactttctc gcattttagt aaaggaaaat
    10261 aaaatgaaaa tattggttac aggttttaat ccttttggag gtgaaaagat taatccagct
    10321 ttggaggctg taaaattatt accatctgag attaatgggg ctgaagttcg ctgggtagaa
    10381 attccaacgg ttttttataa gtcgtcagaa gttttagagg cagaaatatt acgatatcaa
    10441 ccagatgctg tactttgtat tggacaagca ggcggcagga ccggcttaac acctgaacga
    10501 gtggctatta atcaagatga tgctcgcata cctgataacg aaggcaatca accaattgat
    10561 acaccgattc gtattgatgg agcatcggcc tattttagta gtttacctat caaagcgatg
    10621 gtacaagcta tcaaaaaaca gggacttccg gcagttgtat ccaatagtgc aggaaccttt
    10681 gtttgcaatc atttgatgta ccaagctctt tatttagtgg ataaaaaatt ccctaatatg
    10741 agagcaggtt tcatgcatat tccatatatg atggaacaag tagtaaataa gccgaatact
    10801 gcaggaatga gtctatgtga tattgtaaga ggcatagagg tagctattga agctattgta
    10861 gactacaaag ataaggattt gcagttagta ggcggtgaga ctcactgata acctaaaaag
    10921 gatagtcaat tatgcttgtt tactaactat taactatgct aaatcaattg aggttgttta
    10981 cataaaactc tatatcagag aagcctgata tagagttttt tcttgctagt tttaggattt
    11041 tcttgtaaaa tagaaaaagt gaagagaggt atgaaatgag caagaaagat aaaaaaatcg
    11101 aaattcaagt agcggatgcc aaagttaatg ttggtaaaga cagttttgaa ggttatacat
    11161 tgactatcgg taaaaaagtt atcggagaaa ttgccgaatt agacggacaa tttgccatta
    11221 taaagaatgg gaatgtcgat agtttttata aaaaattgga aaaagctgtg gaaattttga
    11281 ttgaaaatta taatttagca aaataagtct tgtttttttg aaattttcat gatataatag
    11341 tccatgttga ttgtaggaga gatagcgaag aggctaaacg cggcggactg taaatccgct
    11401 ccttcgggtt cgggggttcg aatccctctc tctccatttc attaatgggg tatagccaag
    11461 cggtaaggca agggactttg actccctcat gcgttggttc gaatccagct accccagttc
    11521 ttaggtaata atcaagatag aaagcaaaat atcttagggt attttatttt tataattgaa
    11581 agacgtgaat gatatgaaca tgtccttgcg ggtgcttagg aaaaaaatta taagtatgtc
    11641 aagtttaaga aaaacttgat tgttggagga ttttttagat gaacgaattt gaagatttgc
    11701 taaatagcgt tagtcaagtt gagactggtg atgttgttag tgctgaagta ttgacagttg
    11761 atgcgactca agctaacgtt gcaatctctg gaactggtgt tgaaggtgtc ttgactcttc
    11821 gcgaattgac aaacgatcgt gatgcagata tcaatgactt tgttaaagta ggagaagtat
    11881 tggatgttct tgtacttcgt caagtagttg gtaaagatac tgatacagtt acataccttg
    11941 tatctaaaaa acgccttgaa gctcgcaaag catgggacaa acttgttggt cgcgaagaag
    12001 aagttgttac tgttaaagga acgcgtgccg ttaaaggtgg actttcagta gaatttgaag
    12061 gtgttcgtgg atttatccca gcttcaatgt tggatactcg tttcgtacgt aacgctgagc
    12121 gttttgtagg tcaagaattt gatactaaaa tcaaagaagt taacgctaaa gaaaaccgct
    12181 tcatcctttc acgtcgtgaa gttgttgaag cagctactgc agcagctcgc gctgaagtat
    12241 tcggtaaatt ggctgttggt gatgttgtga ctggtaaagt tgctcgtatc acaagcttcg
    12301 gcgctttcat cgaccttggt ggtgttgacg gattggttca cttgactgaa ttgtcacatg
    12361 aacgtaacgt atcaccaaaa tcagttgtaa ctgttggtga agaaattgaa gtgaaaatcc
    12421 ttgatcttaa cgaagaagaa ggacgtgtat cactttcact taaagcaaca gtaccaggac
    12481 catgggatgg cgttgagcaa aaattggcta aaggtgatgt agtagaagga acagttaaac
    12541 gtttgactga cttcggtgca tttgttgaag tattgccagg tatcgatgga cttgttcacg
    12601 tatcacaaat ttcacacaaa cggattgaaa atccaaaaga agctcttaaa gttggtcaag
    12661 aagttcaagt taaagttctt gaagttaacg cagatgcaga acgcgtatca ctttctatta
    12721 aagctcttga agaacgtcca gcccaagaag aaggacaaaa agaagaaaaa cgtgctgctc
    12781 gtccacgtcg tccaagacgt caagaaaagc gtgatttcga acttccagaa acacaaacag
    12841 gattttcaat ggctgatttg tttggtgata tcgaacttta atcaaattga aaattcacaa
    12901 aatcctttgt ttactaaaca agggattttt cggctctttg tcaactgtag tgggttgaaa
    12961 aaaagctaag cttgagaaag gacaaatttt gtcctttctt ttttgatgtt cagagcgata
    13021 aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg tttgataagt
    13081 ttgatgagat tattggtcgc ttccaatttg gcgtttgaat agggtagttg aagggcgttg
    13141 acgattttct ctttgttctt tagaaaggtt ttaaagacag tctgaaaaag aggatgaacc
    13201 tgcttaagat tgtcctcaat aagtccgaaa aatttctctg gttccttatt atagagctga
    13261 tagtggtgtt tcaagtcttc tgaatagctc aaaagcttgt ttaaaatctc tttattggtt
    13321 aagtacatac gaaaagtagg acgataaaat cgcttatcac tcagtttacg gctatcctgt
    13381 tgaatgagtt tccagtagcg cttgatagcc ttgtattcat gagactttcg atgaaactga
    13441 ttcatgattt ggacatgcac acgactcata gcacggctaa gatgttgtac aatatgaaag
    13501 cgatcaagaa cgattttagc attcgggagt gaaacagtct gggagactgt ttcagcctga
    13561 gcctagaaat ttgaaagcga agttgtctag ctaagtcata gtaaggacta aacatatcca
    13621 tagtaatgat tttcacttga caacgaacgg ctctatcata tttaagaaag tgatctcgga
    13681 tgatagcttg tgttctacct tcaagaacag tgatgatatt gagcttttca aaatcttgcg
    13741 caataaagct catctccatc ttccgattga aacagtcact ccccggactg tttcaacgtc
    13801 ccaagacata atctcaggca gatttctaaa attacactca aagtggaagt cattgagctt
    13861 tcgaatgaca gttgaagttg agatggaaag ctgatgggca atatcggtca tagaaatctt
    13921 ttcaattaac ttttgagcaa tcttttggtt gatgatacga gggatttggt gattcttctt
    13981 gacgatagaa gtttcagcga ccatcatttt tgaacagtga tagcacttga atcgacgctt
    14041 tctaaggaga attctagtag gcataccagt cgtttcaaga taaggaattt tagacggttt
    14101 ttgaaagtca tgtttcttca tttgacttcc gcactcaggg caagatgggg tgtcataatc
    14161 cagtctagcg atgatttcct tgtgtgtatc cttattgatg atgtctaaaa tctggatatt
    14221 agggtcttta atgtctagta attttgtgat aaaatgtaat tgttctatat gattctttct
    14281 aatgagttgt tttgttgctt ttcattatag gtcatatggg actttttttc tacacaaaat
    14341 aggctccata atatccatag gggatttacc cactacaaat attatagagc ccaaaatcct
    14401 ttgtttacta aacaagggat ttttcttttg tctctgctcc ttttttgata taatagttct
    14461 atgttaaaat cagaaaaaca atcacgttat caaatgttaa atgaagaatt gtccttccta
    14521 ttggaaggcg aaaccaatgt tttggctaat ctttccaacg ccagtgctct cataaaatca
    14581 cgttttccta ataccgtatt tgcaggcttt tatttgttcg atggaaagga attggtttta
    14641 ggccccttcc aaggaggtgt ttcctgcatc cgtattgcac taggcaaggg tgtttgtggt
    14701 gaggcagctc actttcagga aactgttatt gttggagatg tgacgaccta tctcaactat
    14761 atttcttgtg atagtctagc taaaagtgaa attgtggtgc cgatgatgaa gaatggtcag
    14821 ttacttggag ttctggatct ggattcttca gagattgagg attacgatgc tatggatcga
    14881 gattatttgg aacaatttgt cgctattttg cttgaaaaga caacatggga ctttacgatg
    14941 tttgaggaaa aatcttaatg tatcaagcac tttatcgaaa atatagaagt caaaacttct
    15001 cccagttagt tggtcaagaa gttgtggcta agactcttaa acaagcggtg gagcaagaga
    15061 aaataagtca cgcttatctt ttttctggtc ctcgtggaac gggaaaaacc agtgttgcta
    15121 aaatctttgc caaggctatg aactgtccca atcaagtggg tggcgaacct tgcaataact
    15181 gctatatttg tcaagcagtg acggacggta gtttagaaga tgtcattgaa atggatgcag
    15241 cttctaataa tggggtagat gaaattcgcg aaattcgtga taaatctacc tatgcgccta
    15301 gccttgctcg ttataaggtt tatatcatag atgaggttca catgctgtct acaggggctt
    15361 ttaatgccct cctaaagacg ctggaagaac caacacagaa tgtagtcttt attttggcca
    15421 ctactgaatt gcacaagatt cctgctacta ttctatcccg tgtgcaacgt tttgagttta
    15481 aatcaattaa gacacaggat attaaggaac atattcacta tatcttagaa aaagaaaata
    15541 tcagttctga accagaggct gtggaaatca ttgccaggcg ggcggaaggt ggaatgcggg
    15601 acgccttgtc tattttggat caagccctga gtttgacaca gggaaatgag ctgacgactg
    15661 ctatctctga agaaattact ggcaccatta gcctatcagc cttggatgat tatgtggcgg
    15721 ccttgtctca acaggatgtt cccaaagctt tgtcttgctt gaatcttctt tttgacaatg
    15781 gtaagagcat gactcgtttt gtgaccgatc ttttgcacta tttaagagac ttgttaattg
    15841 ttcaaacagg gggagaaaat actcatcata gttcagtctt tgtagaaaat ttggcacttc
    15901 ctcaaaaaaa tctgtttgaa atgattcgct tagcaacagt gagtttagca gatattaagt
    15961 ctagtttgca gcccaagatt tatgctgaaa tgatgaccgt ccgtttggcg gaaatcaagc
    16021 ccgaaccagc tctatcagga gcggttgaaa atgaaattgc tacgctgaga caggaagttg
    16081 cccgtctcaa acaagagctt tctaatgtag gtgcggttcc taaacaagtt gcaccagctc
    16141 ctagtcgacc agctacgggc aaaacagtct atcgtgtcga tcgcaataaa gtgcaatcta
    16201 tcttacaaga ggccgtcgaa aatcctgatt tagcacgtca aaatctaatt cgtttgcaga
    16261 atgcctgggg agaggtaatt gaaagtctag gtgggccgga caaggctctg ctagttggtt
    16321 ctcaaccggt tgctgccaat gaacaccatg ctattcttgc ttttgagtct aacttcaatg
    16381 ctggtcaaac tatgaaacga gacaatctca ataccatgtt tggtaatatc ctcagtcagg
    16441 cggcaggttt ttcacctgag attttagcta tttccatgga ggaatggaaa gaagttcgcg
    16501 cagccttttc agccaaagcc aaatcttctc aaactgaaaa agaagtagaa gaaagcctga
    16561 ttccagaagg atttgaattt ttggctgata aagtgaaggt agaggaagac taaagaaaga
    16621 tttcatgata caataagttt atgaataaac aacaatttat tattatggcg ctgtttacag
    16681 ctgctgagac ctattttttc aatgaagcct ggatgactgg ccgctatatt atggcagcct
    16741 tttgggcaat tttactcttt agaaatttcc gagtcagtta tgtgatgggc aaaatcgttg
    16801 atgtcatcga tcagcatttt aataggaaag actagccctc agcttccaga caaaatcaaa
    16861 gccttttagg cttttttttg ttatactaga aaagtatatt tatagaattt ttgctctatt
    16921 tctggggaaa tcagacgttt ttctagtaag tactgtaaaa gttttgaaaa agaaaggaac
    16981 tatcatgtca gtattagaga ttaaagatct tcacgttgag attgaaggaa aagaaatttt
    17041 aaaaggggtt aacctgaccc tgaaaacagg agaaattgcc gctatcatgg gaccaaatgg
    17101 tacaggtaaa tcgactcttt ctgccgctat catgggaaat ccaaactatg aagtaactaa
    17161 aggtgaagtt ttgtttgatg gcgtaaacat ccttgagttg gaagtggatg agcgtgcgcg
    17221 tatgggactt ttccttgcta tgcaataccc atcagaaatc cctggaatta ccaatgctga
    17281 gtttcttcgt gccgctatga atgcgggtaa agaaggtgat gagaagattt cagttcgtga
    17341 gtttattact aagctagatg aaaaaatgga attgctcaac atgaaagaag aaatggcaga
    17401 gcgttacctc aacgaaggct tctctggtgg tgagaaaaaa cgcaatgaaa ttcttcaact
    17461 tttgatgttg gagccaacat ttgctctttt ggacgagatt gactcaggtc ttgatattga
    17521 cgctcttaaa gttgtgtcta aaggtgtcaa tgccatgcgt ggtgaaggtt ttggtgctat
    17581 gatcatcact cactaccaac gtcttttgaa ctatatcaca cctgatgtgg tacacgtgat
    17641 gatggaaggt cgtgttgtcc tttctggtgg tccagaattg gctgcgcgtt tggaacgtga
    17701 aggatacgca aaattagctg aagaacttgg ctacgactac aaggaagaat tgtaattccc
    17761 tcgtatcttt taggagaagt aaatgactag agaaaatatt aaactttttt cagaaatgca
    17821 cgctgaacca agctggttgg ctgatctccg tcaaaaagct tttgacaaga ttgagacttt
    17881 ggaattacca gttattgagc gtgtcaaatt ccaccgttgg aatctgggtg atggaacgat
    17941 tacagaaaat gagccatcag caaatgttcc agatttcaca gctttagatc atcacttgaa
    18001 gttggtgcaa gtaggaactc aaactgtttt cgaacaaact ccagttgagt tagctgaaca
    18061 gggtgttgtc ttcacagact ttcactcagc tttagaagaa attccagagc tgatcgaaga
    18121 attcttcatg tcatctgtta agtatgatga tgacaagttg gcggcttacc acacagctta
    18181 ctttaacagt ggtgctgtac tctatattcc agataacgta gaaatcacag agccaattga
    18241 aggaattttc taccaagata gcgatagcaa tgtgccgttt aacaagcata ttatgattat
    18301 cgctggtaaa aattctaaga ttagttatct ggagcgttta gagtcacgcg gtgaaggaag
    18361 tgacaaagca actgccaata tcacagtgga agtgattgca cgttctggtg cgcaagtcaa
    18421 gtttgctgct attgaccgtc taggtgaaaa cgtcactgcc tacattagcc gtcgtggtaa
    18481 attaggcaac gatgcaagta ttgactgggc tatcggtgtc atgaacgaag gaaatgtcgt
    18541 tgctgatttt gatagtgact tgattggtaa tggtagccat gctgacctca aggttgtagc
    18601 tctttcaagt ggtcgtcagg tacaagggat tgatactcgt gtaactaact atggctgcaa
    18661 ctctatcgga aatatcctac aacatggggt tatccttgaa aaagcaactt tgactttcaa
    18721 tggtatcggc cacatcatca agggtgctaa gggagcagat gcccaacaag agagccgtgt
    18781 tctcatgctt tcagaccaag cgcgttcaga tgctaaccca attcttttga ttgatgaaaa
    18841 tgacgtcact gcaggacatg cagcctctat tggtcaggta gatccagaag atatgtacta
    18901 cctcatgagt cgtggattgg ataaggcaac tgcagagcgt ttggttgttc gtggtttcct
    18961 tggatctgtt atcgtggaga ttccagtcaa ggaagttcgt gatgaaatga ttgcaactat
    19021 cgaagagaaa ttgtcaaaac gctaagggga agcctatgtt agatgtagaa gcgattcgca
    19081 aggattttcc aattttagat cagattgtca atgatgaacc tctggtctat ctggacaatg
    19141 ctgcgacgac acaaaaacca ctagtagttc tgaaagctat taacagttac tatgagcagg
    19201 acaatgccaa tgttcaccgt ggtgtccata ccttagcgga acgagcgaca gcttcttatg
    19261 aagctgctcg tgaaaccatt cgtaagttta ttaatgcagg ctctacaaag gaagttctct
    19321 ttaccagagg aacgacaacc agccttaact gggtggcacg ctttgctgag gaaattctca
    19381 ctgagggaga ccaggtcttg atttcagtaa tggaacacca ttctaatatc attccatggc
    19441 aggaagcttg tcgaaagact ggagcagagc ttgtctatgt ctatcttaaa gacggtgcct
    19501 tggatatgga ggatttgcga gctaaattga ctgataaggt taaatttgtt tccctagctc
    19561 atgcctccaa tgttcttggt gtggtcaatc cgatcaagga aatcactcaa ttagcccacc
    19621 aagttggggc aatcatggta gtggatggtg ctcaatctac acctcatatg aagattgatg
    19681 tccaggactt ggatctggac tttttcgcct tttcgggtca caagatggct ggtccgactg
    19741 gtatcggtgt cctttacggc aaagaaaagt atcttgagca aatgtctcca gtagaatttg
    19801 gcggcgagat gattgatttt gtctacgagc aatctgctag ttggaaggaa ttgccttgga
    19861 aatttgaggc tggaacgcca aatatggcag gagctattgg acttgcgact gcagttgatt
    19921 atctggaaaa gattggtatg gatgccgttg aagctcatga acaggaattg attgcgtacg
    19981 tctatccaaa actgcaggca attgagggat tgaccattta cggttctcag gatttggctc
    20041 aacgttcggg tgttattgcc tttaacctag gtgatctcca tcctcacgat cttgcgacgg
    20101 ctctggatta tgaaggagtg gctgttcgtg ctggtcacca ttgtgcgcaa cccttgcttc
    20161 agtatttgga agtcccagca acagctcgtg caagttttta tatctataat accaaggcag
    20221 attgcgacaa actagtcgat gccctacaaa agacaaagga gtttttcaat ggcactttct
    20281 aaactagata gcctttatat ggcagtggta gcagaccatt cgaaaaatcc acatcaccaa
    20341 gggaagttag aagacgctga gcaaatcagt ctcaacaatc cgacttgtgg agatgtcatc
    20401 aatctctctg tcaagtttga tgcagaggac cgtttggaag atattgcttt tctaaattca
    20461 ggatgcacga tttcaactgc ttctgctagt atgatgacag atgccgtttt aggaaaaacc
    20521 aaacaagaaa ttttagaact ggcgactatt ttttctgaaa tggttcaagg gcaaaaagat
    20581 gagcgtcaag accaacttgg agacgcggca ttcttgtcag gtgttgccaa attccctcaa
    20641 agaatcaagt gtgcaaccct agcttggaat gcccttaaga aaacaattga aaatcaagaa
    20701 aaacagtaag acaagtttct tttgtcttat gaattattag aaatgaagaa agaaaggata
    20761 ttatggctga agaaagagta gaaccaaaac caattgacct tggtgaatat aaatttggtt
    20821 tccatgacga tgtagagcct gtcttatcga caggaaaagg actcaacgaa ggtgttattc
    20881 gtgaattatc tgctgctaag ggtgagcctg agtggatgtt ggagttccgt ttgaagtctt
    20941 atgaaacctt caaaaaaatg cccatgcaaa cttggggagc agacttgtca gagattgact
    21001 ttgatgactt aatctactac caaaaaccat ctgacaaacc agcccgttct tgggatgatg
    21061 tacctgaaaa gattaaagaa acctttgaac gtatcgggat tccagaagct gaacgtgctt
    21121 atttagcagg ggcttctgcc cagtacgagt cagaagtggt ttaccacaac atgaaggaag
    21181 agttccaaaa attaggtatt atctttacag atacagattc cgcactcaag gaatacccag
    21241 acttatttaa tcaatacttt gcgaagttgg taccgccgac agataacaag ttggcagccc
    21301 tcaactcagc agtatggtcg ggtggaactt ttatctacgt gccaaaaggt gtcaaggtag
    21361 atattccact tcaaacttat ttccgtatca ataacgaaaa tataggtcag ttcgaacgta
    21421 ccttgattat cgttgatgag ggagcaagcg tccactacgt agaaggatgt acagcaccaa
    21481 catattcaag caatagctta cacgctgcca ttgtagaaat ttttgctttg gacggagctt
    21541 atatgcgtta tacaactatc caaaactggt ctgataacgt ctataacttg gtaacaaagc
    21601 gtgctaaggc tcaaaaggat gccactgttg agtggattga tggaaacttg ggtgccaaaa
    21661 cgactatgaa atatccatct gtttaccttg atggagaagg agcgcgtggt accatgctct
    21721 ctatcgcctt tgctaatgca gggcaacacc aagacacggg tgctaagatg attcacaatg
    21781 ctccacatac cagctcgtct attgtgtcta aatccatcgc taaaggtgga ggaaaggttg
    21841 actaccgtgg acaagtcacc tttaacaaga actctaagaa atctgtttcc cacattgaat
    21901 gtgataccat tatcatggat gacttgtcag catcagatac tattccattt aatgaaattc
    21961 acaactcgca agtggctttg gaacacgaag ccaaagtatc taagatttca gaagagcaat
    22021 tgtattatct catgagccgt ggattgtcag aatctgaggc aactgaaatg attgtcatgg
    22081 gatttgtaga accctttaca aaagaacttc caatggaata cgcagttgag ctgaaccgct
    22141 tgattagcta tgaaatggaa gggtcagttg gataaaattt gattttatac tcttcgaaaa
    22201 tctcttcaaa ccacgtcagc atcgccttac cgtatgtatg gttactgact tcgtcagttt
    22261 catctacaac ctcaaaacag tgttttgagc aacctgaggc tagcttccta gtttgttctt
    22321 tgattttgag tattagattt actcaaaatc aaggattttg aagatgaact tgtatcaaaa
    22381 aatcgcggtt taaaatcgcg attttttata atttctcgtt aacaaagcgg acaaactgat
    22441 tccaccaaac ttttaagaag aaggcttttt caattttctt gtctgctacc atttcgaaac
    22501 tagggcgctc tgtggtgatg taaccttgac caatcaagtc cttgtcttca taagtcaaat
    22561 ggccaaccac tgttccagct tcaagtggtg ctgggattgc tttggaatca ggtgtgaatt
    22621 gaacagattg ggaagattga ttcccaacac gttcgattag atagatatcc tctggagcca
    22681 ctgcagttac tgtatcttct tttccatctt gtacaggggc tttgctatct tgataggcat
    22741 cgccttgttg aacgattttg cgaagtgtaa atgtagaaga aatataatcc attagggaag
    22801 atgtagctgt aaatcgagcg taaggattat tgtcttgatg atctgcattt aaaacaactg
    22861 tgatgactct catgcctttt tcgacagtag taccaacaaa agactctcca gccttatctg
    22921 ttgttcctgt ttttagccca tcaaaaccac cacggtaagc aggcatacct tctaacatgt
    22981 agttggttga agtgattgtc atcccagcaa aagtagaaga aggttttttg gtgatttcta
    23041 agacttgtgg gtattttttg atgaggttgc gagcaacgat agcgacatca taagcactaa
    23101 gcttattttc ctcatctttt ttagaacctg ggtaaatgtt atcccctaga gtttcattgt
    23161 taagacctgt cgtattgaca acagtggcat cctgaattcc ccattccaag agttttgccc
    23221 gcatcatatc gacgaaatct ttttctgagc cagcaatttt ctcagctagg gcaatagcgg
    23281 cgctgttggc actagatacc agagttgctt caagcaactc ttcgacagta taattacggg
    23341 cctccatagg aatattactg gcttcagaat ttgtcgtcaa ttgataagga taatcagaaa
    23401 tatctacagg agtggagagg gtaatacttc cgttttccaa agcttcatag accagataaa
    23461 cagtaatcaa ttttgttatg gaagcaattt cgacaggttg cgttgcatcc ttctcataga
    23521 gaattttacc agtatttgcc tcaacagcaa tcgcatgttt agcggcaatg gtaaaatctt
    23581 gagcaacagc agtagaagca ccccctaaaa gagagacagt taacaaagtt aaaaatattt
    23641 ttttcatagt agtcttattc tatcataaag aaaaaaaata ttcttgcttt aataattcat
    23701 ctgttaagct ttttgaaaat atggtaaaat aaagtgaggg aggtaactca tgtttcgtag
    23761 aaataaatta tttttttgga ccacagaaat tttactctta accatcatct tttacctatg
    23821 gagacagatg gggtctttga ttaacccttt tgttagcgtg cttaatacaa ttatgattcc
    23881 atttttatta ggaggctttc tttattattt gacaaaccct attgttactt tcttaaataa
    23941 agtctgtaaa ctcaatcgtt tgcttggtat tttaattacc ttgtgtactt tggtctgggg
    24001 aatggtcata ggtgttgtct atctcttacc tattttgatt aatcagttat ctagtttgat
    24061 tatatctagt caaactattt atagtcgagt acaagactta atcatagact tatctaatta
    24121 tcctgcgctc cagaatttgg atgtagaagc tacaattcag cagttaaact tatcctatgt
    24181 ggatattctt caaaatatcc taaatagcgt atcaaatagt gtggggagcg tcttgtcagc
    24241 tcttatcagt actgttttga ttttgattat gactccagtt tttttggttt atttcttatt
    24301 agatggacat aaattcttgc ccatgcttga aagaacgatt ctaaagaggg atcgcttgca
    24361 tattgcaggc ttattaaaga atttaaatgc gacgattgct cgctatatta gtggagtttc
    24421 gattgacgca atcattatag gttgtttggc ttatattggc tatagtatta ttggtttaaa
    24481 atatgcttta gtttttgcca ttttttctgg tgtagccaat ttaattcctt atgtggggcc
    24541 aagtattggt ttgattccta tgatcatcgc aaatatattc actgatcccc atagactgct
    24601 gattgcagtg atttatatgc ttgttgttca gcaggtagat ggcaatatct tatatcctcg
    24661 aatcgtagga agtgttatga aggttcatcc aatcacgatt ttagttttac ttttgttgtc
    24721 aagcaatatc tatggtgtag ttggaatgat tgtcgcagtg ccaacctatt ctatcttgaa
    24781 agaaatttct aagttcttat cccgtttgta tgaaaatcat aaaataatga aagaacgaga
    24841 aagagaatta gctaagtaaa agtcaggaga accctgattt ttctttactg gaagtggcct
    24901 ttagattaga agactgaaaa taagttaaag tcttaaacta attttcacag ctaagaatag
    24961 tagaagttaa tctgataaaa atcgaaaaaa ccagtggaat tctgtgtcag ggtaagttcc
    25021 actggttttc atagtctatt aaagttcgaa tgaaacctat ttatagtaga ttgaaactag
    25081 aatagtacac ctctaattct aaaacattgt tagaaatcga tttgactgtc cttatctatt
    25141 cgttctattc ttatttcatt ttactatatt ttggtgcaat aagtgaaaag tagaccgaat
    25201 aatataagga ttgattttat agtttttaaa ctcaaatgaa ttgaaataaa gagagtacga
    25261 aaattctcat ctgaaagtat tttagaataa ttctcttcgt gaatttcttc aaaacagata
    25321 gcttcatctt aggtatgtga tttctttttg catttttgag ttagataagg tataatggtt
    25381 ttattgtctt ttggggtcgt tacggattcg acaggcatta tgaggcatat tttgcgactc
    25441 gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa aataacactt cttacgctct
    25501 agctgcctaa aaaccagcag gcgtgacccg atttggattg ctcgtgttca atgacaggtc
    25561 ttattattag cgagatacga ttaagccttg tctagcggct tgataagaga ttgatagact
    25621 cgcagtttct agacttgagt tatgtgtcga ggggctgtta aaataataca taacctatgg
    25681 ttgtagacaa atatgttggc aggtgtttgg acgtgggttc gactcccacc ggctccatta
    25741 ttcctttgca ttcttttgca ttccttggta aaacgttgtt aaatcaacgt tttttatttt
    25801 tatctttggt attcctttgc attcttttgc taaaaaggga gtcacaaaca gaccctattt
    25861 taaaaaaagg atagaaaaaa ggatacaaca tttgtcgcat cctaaaaata atcttttttc
    25921 gacggaagac atgggattcg aacccacgca cgctattaca cgcctaccgc gtttccaaca
    25981 cggcctctta agcctcttga gtaatcttcc aatacttact caaatagtct accataaagg
    26041 ctcttatctt gcaataaaaa ttctagaaat aagaaaaatg atagattttg aaagaaaatg
    26101 ataaaaaatg cttgacttcg aaagaaagta tgatagaatg aatagtgtaa acgataacag
    26161 gaggtgattc agtgttaaaa acagaacgta aacaactaat tttagaggag ttaaatcagc
    26221 atcatgtagt ttctctagaa aaattagtta gtttgctaga aacgtcagaa tcaacggttc
    26281 gaagagactt ggatgagttg gaagcggaaa acaagcttcg tcgtgtgcat ggtggagcag
    26341 aactccccca ctccttacag gaagaagaaa ccattcaaga aaaatctgtc aaaaaccttc
    26401 aagaaaagaa gttgctggct cagaaagcag cctctctcat taaagaaaaa gatgtcatct
    26461 ttatcgatgc tggaacaaca actgcttttt tgattcatga attggtcaat aagaatgtta
    26521 cagttgtgac caactccatt caccatgccg ctcagttggt tgaaaagcag attccaactg
    26581 tcatggttgg aggaaacgtc aagacggcga cagatgctag tatcgggggc gttgctctta
    26641 accagattaa ccaattgcac tttgaccgtg cctttatcgg aatgaatggt gttgacgatg
    26701 gctattatac gactcctgat atggaggagg gagctgtgaa aagagctatt ttggagaatg
    26761 ccaagcagac ctacgtcttg gtggattcgt caaaaattgg acaaacttgc tttgccaagg
    26821 tagcaccact caaacgcgct atcgttatca ctagtcaagg gcatgagctc ttgcaggtta
    26881 ttaaggagaa aacggaggta atagaagtat gatttataca gtcacactca atccatccat
    26941 tgactatatc gttcgtttgg accaagtcaa agttggtagt gtaaatcgta tggacagtga
    27001 tgataagttt gctggtggga aaggaatcaa tgtcagccgt gtcttgaaac gtttgaatat
    27061 accaaataca gcgacgggat ttatcggtgg ctttactggt aaatttatca cagatacttt
    27121 agcagaggaa gaaatcgaga cacgttttgt ccaggtggca gaagatactc gtatcaatgt
    27181 taaaatcaaa gcagaccaag aaacagaaat caacggaacg ggtccaactg ttgaatcggt
    27241 tcagctagaa gaattgaaag ctattttatc tagtctgaca gcagaagata cagttgtctt
    27301 tgcaggttca agtgctaaaa atctaggcaa tgttatctat aaggatttga tttccttgac
    27361 gcgccagact ggtgcgcaag tggtctgtga ctttgaagga cagaccttaa ttgatagttt
    27421 ggactaccag cctcttcttg taaaaccaaa caatcatgaa cttggagcga tttttggggt
    27481 taaactcgaa agtttagatg aaattgagaa atacgctcgt gagttactgg ctaagggtgc
    27541 tcaaaatgtt attatctcta tggctggtga tggtgccctt cttgtcacat ctgagggagc
    27601 ttacttcgct aaaccaatca aaggaacagt caaaaattca gttggagctg gtgattctat
    27661 ggttgctgga ttcacaggtg aatttgtcaa atcaaaagac gtagtagaag ccttcaaatg
    27721 gggagtggct tgcggaacgg caactacctt ctcagatgac ttggcaacgg cggaatttat
    27781 taaagaaaca tatggaaaag ttgaggtaga aaaaagatga aaattcaaga cctattgaga
    27841 aaagatgtca tgttgctaga tttgcaggca actgaaaaaa cagctgtcat cgacgagatg
    27901 attaaaaatt tgacagagca cggttatgta acagattttg aaacatttaa agaaggaatt
    27961 ttggcgcgtg aagctttgac ttctactggt ttgggtgatg gaatcgcaat gcctcacagc
    28021 aaaaacgctg ctgtcaaaga agcgacagtt ctatttgcta agtcaaataa gggtgttgac
    28081 tacgagagct tggatggaca agcaactgac ctcttcttca tgattgcagc tccagaaggt
    28141 gccaatgata ctcacttggc agccttggca gaattgtctc aatacttgat gaaagacggt
    28201 tttgcagaca aacttcgtca agcaacatct gcagaccaag ttatcgaact ttttgaccaa
    28261 gcttcagaaa aaactgagga acttgttcaa gcacctgcta atgactctgg tgactttatc
    28321 gtagctgtta cagcttgtac aacaggtatt gcccacactt acatggccca agaagccctt
    28381 caaaaagtag ctgctgaaat gggggttggt atcaaggtcg aaaccaacgg tgctagcggt
    28441 gttggaaatc aactaactgc agaagatatc cgtaaggcta aagctattat cattgcagca
    28501 gacaagaccg ttgaaatgga tcgatttgat ggaaaaccat tgatcaatcg tccagttgct
    28561 gacggtatcc gtaagacaga agagctaatt aacttggctc tttcaggaga tactgaagtc
    28621 taccgtgccg ctaatggtgc caaagctgca acagcctcta acgaaaaaca aagccttggt
    28681 ggtgccttgt acaaacactt gatgagtggt gtatctcaaa tgttaccatt cgttatcggt
    28741 ggtggtatca tgattgccct tgccttcttg attgacggtg ctttgggtgt tccaaatgaa
    28801 aaccttggca atcttggttc ttaccatgag ttagcttcta tgttcatgaa aattggtgga
    28861 gctgcctttg gtttgatgct tccagtcttt gcgggttatg ttgcctactc tattgctgaa
    28921 aaaccgggtt tggtagcagg tttcgtggct ggtgctattg ccaaagaagg ttttgccttt
    28981 ggtaaaattc cttatgccgc aggtggtgaa gcaacttcaa ctcttgcagg tgtctcatct
    29041 ggtttcctag gtgcccttgt tggtggattt atcgcaggtg ccttggttct tgccatcaag
    29101 aaatacgtta aagttcctcg ttcactcgaa ggtgctaaat caatccttct attgccactt
    29161 cttggaacaa tcttgacagg atttgttatg ctagctgtga atatcccaat ggctgcaatc
    29221 aacactgcta tgaatgactt cctaggcggt cttggaggag gttcagctgt ccttcttggt
    29281 atcgtccttg gtggaatgat ggctgttgac atgggtggac cagttaataa agcagcttat
    29341 gtctttggta caggtacgct tgcagcaact gtttcttcag gtggttctgt agccatggca
    29401 gcagttatgg ctggaggaat ggtgccacca cttgcaatct ttgtcgcaac tcttcttttc
    29461 aaagataaat ttactaagga agaacgtaac tctggtttga caaacatcat catgggcttg
    29521 tcatttatca ctgagggagc gattccattt ggtgccgctg acccagctcg tgcgattcca
    29581 agcttcatcc ttggttcagc agtagcaggt ggactcgttg gtcttactgg tatcaaactc
    29641 atggcgccac acggaggaat cttcgttatc gcccttactt caaatgctct cctttacctc
    29701 gtttctgtct tggtaggagc aatcgtaagt ggtgtggttt atggttacct acgcaaacca
    29761 caagcataaa aaatagaaaa atgaaaagat tggaccgttt ggtgcagtct ttttctcttc
    29821 ccgaaatgcc tgtgaaatat ggtataatag aagaatggca aacaagaata caagtacaac
    29881 aagacggaga ccgtctaaag cagaactgga aagaaaagaa gcgattcaac gaatgttgat
    29941 ttcattagga attgcgattt tattgatttt cgcagccttc aaattagggg ctgcaggtat
    30001 aaccctttat aatttaattc gcttgctagt gggtagccta gcttatctgg cgatattcgg
    30061 cctattaatc tatctcttct ttttcaagtg gatacgaaaa caggaaggac tcttatctgg
    30121 ctttttcacc atatttgctg gcttactctt gatttttgaa gcctacttgg tttggaaata
    30181 tggtttggac aagtccgttc taaaagggac catggctcag gttgtgacag atctgactgg
    30241 ttttcgaacg actagctttg ctggaggggg cttgataggg gtcgctcttt atattccaac
    30301 agcctttctc ttttcaaata tcggaactta ctttattggt tctatcttga ttttagtggg
    30361 ttctctccta gtcagccctt ggtctgttta cgatattgct gaatttttca gtagaggctt
    30421 tgccaaatgg tgggaagggc acgagcgtcg aaaagaggaa cgctttgtca aacaagaaga
    30481 aaaagctcgc caaaaggctg agaaagaggc tagattagaa caagaagaga ctgaaaaagc
    30541 cttactcgat ttgcctcctg ttgatatgga aacgggtgaa attctgacag aggaagctgt
    30601 tcaaaatctt ccacctattc cagaagaaaa gtgggtggaa ccagaaatca tcctgcctca
    30661 agctgaactt aaattccctg aacaggaaga tgactcagat gaccaagatg ttcaggtcga
    30721 tttttcagcc aaagaagccc ttgaatacaa acttccaagc ttacaactct ttgcaccaga
    30781 taaaccaaaa gatcagtcta aagagaagaa aattgtcaga gaaaatatca aaatcttaga
    30841 agcaaccttt gctagctttg gtattaaggt aacagttgaa cgggccgaaa ttgggccatc
    30901 agtgaccaag tatgaagtca agccggctgt tggtgtaagg gtcaaccgca tttccaatct
    30961 atcagatgac ctcgctctag ccttggctgc caaagatgtc cggattgaag caccaatccc
    31021 tgggaaatcc ctaatcggaa ttgaagtgcc caactccgat attgccactg tatctttccg
    31081 agaactatgg gaacaatcgc aaacgaaagc agaaaatttc ttggaaattc ctttagggaa
    31141 ggctgttaat ggaaccgcaa gagcttttga cctttctaaa atgccccact tgctagttgc
    31201 aggttcaacg ggttcaggga agtcagtagc agttaacggc attattgcta gcattctcat
    31261 gaaggcgaga ccagatcaag ttaaatttat gatggtcgat cccaagatgg ttgagttatc
    31321 tgtttacaat gatattcccc aactcttgat tccagtcgtg accaatccac gtaaagccag
    31381 caaggctctg caaaaggttg tggatgaaat ggaaaaccgt tatgaactct ttgccaaggt
    31441 gggagttcgg aatattgcag gttttaatgc caaggtagaa gagttcaatt cccagtctga
    31501 gtacaagcaa attccgctac cattcattgt cgtgattgtg gatgagttgg ctgacctcat
    31561 gatggtggcc agcaaggaag tggaagatgc tatcatccgt cttgggcaga aggcgcgtgc
    31621 tgcaggtatc cacatgattc ttgcaactca gcgtccatct gttgatgtca tctctggttt
    31681 gattaaggcc aatgttccat ctcgtgtagc atttgcggtt tcatcaggaa cagactcccg
    31741 tacgattttg gatgaaaatg gagcagaaaa acttcttggt cgaggagaca tgctctttaa
    31801 accgattgat gaaaatcatc cagttcgtct ccaaggctcc tttatctcgg atgacgatgt
    31861 tgagcgcatt gtgaacttca tcaaggctca ggcagatgca gactacgatg agagttttga
    31921 tccaggtgag gtttctgaaa atgaaggaga attttcggat ggagatgctg gtggtgatcc
    31981 gctttttgaa gaagctaagt ctttggttat cgaaacacag aaagccagtg catccatgat
    32041 tcagcgtcgt ttgtcagttg gatttaaccg tgcgacccgt ctcatggaag agcttgagat
    32101 ggcaggtgtc attggtccag ctgaaggtac caaaccaaga aaagttttac aacaataaaa
    32161 aaatagcttc tttccaagtt tggaaggagg ctattttagt gattattgat tagttttatt
    32221 ttccgaagtt ggggtattgg actgtttttc gttttcagta gcaggtttac ttggagtagg
    32281 agcaggagta gaagaatcct gagttgatgt tttctgctct tcttttttct cttccttgac
    32341 gctggatttt ggcgtttctt cttgttgtgt tttttcttga gaagtcttat tttccttatt
    32401 gggactagta ttttcctgag gggattcctt ttgaatttct ttgacaattg ttgtcgtctg
    32461 gcttgttgta ggttcctttt tagtattttt gttattatcc aaggcgttca taatcgtgat
    32521 actagcggta atcaagccaa ggatactagc gatagtcgca acggtttttt gaaagactgt
    32581 aaagcctttt ttgatgtgtt ctgtttttgg ttttgaagtt ctacgataat tagacataca
    32641 ttctctcctt taatt
//
LOCUS       DAVKZI010000024        30075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKZI010000024 DAVKZI010000000
VERSION     DAVKZI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.024"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            470..1633
                     /locus_tag="VXB18_001278"
     CDS             470..1633
                     /locus_tag="VXB18_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0382477.1"
                     /translation="MDRIRVSKRVEKKLAKGLVLLESSDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1630..2307
                     /locus_tag="VXB18_001279"
     CDS             1630..2307
                     /locus_tag="VXB18_001279"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0382478.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2297..3151
                     /locus_tag="VXB18_001280"
     CDS             2297..3151
                     /locus_tag="VXB18_001280"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0382479.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3170..4237
                     /locus_tag="VXB18_001281"
     CDS             3170..4237
                     /locus_tag="VXB18_001281"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0382480.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPASITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4247..5413
                     /gene="aroC"
                     /locus_tag="VXB18_001282"
     CDS             4247..5413
                     /gene="aroC"
                     /locus_tag="VXB18_001282"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0382481.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVFIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5423..6526
                     /locus_tag="VXB18_001283"
     CDS             5423..6526
                     /locus_tag="VXB18_001283"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0382482.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6537..6875
                     /locus_tag="VXB18_001284"
     CDS             6537..6875
                     /locus_tag="VXB18_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0382483.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6967..8250
                     /gene="aroA"
                     /locus_tag="VXB18_001285"
     CDS             6967..8250
                     /gene="aroA"
                     /locus_tag="VXB18_001285"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0382484.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDSKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8243..8719
                     /locus_tag="VXB18_001286"
     CDS             8243..8719
                     /locus_tag="VXB18_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0382485.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8716..9564
                     /gene="pheA"
                     /locus_tag="VXB18_001287"
     CDS             8716..9564
                     /gene="pheA"
                     /locus_tag="VXB18_001287"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0382486.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9561..10835
                     /gene="psr"
                     /locus_tag="VXB18_001288"
     CDS             9561..10835
                     /gene="psr"
                     /locus_tag="VXB18_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0382487.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11114..11959
                     /locus_tag="VXB18_001289"
     CDS             11114..11959
                     /locus_tag="VXB18_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0382488.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11949..13052
                     /locus_tag="VXB18_001290"
     CDS             11949..13052
                     /locus_tag="VXB18_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0382489.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSTSNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            13054..14040
                     /locus_tag="VXB18_001291"
     CDS             13054..14040
                     /locus_tag="VXB18_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0382490.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            14056..15489
                     /locus_tag="VXB18_001292"
     CDS             14056..15489
                     /locus_tag="VXB18_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0382491.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLVHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15517..16551
                     /locus_tag="VXB18_001293"
     CDS             15517..16551
                     /locus_tag="VXB18_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0382492.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYFFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16752..17489
                     /gene="mecA"
                     /locus_tag="VXB18_001294"
     CDS             16752..17489
                     /gene="mecA"
                     /locus_tag="VXB18_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0382493.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17640..18926
                     /locus_tag="VXB18_001295"
     CDS             17640..18926
                     /locus_tag="VXB18_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0382494.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18928..19797
                     /locus_tag="VXB18_001296"
     CDS             18928..19797
                     /locus_tag="VXB18_001296"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0382495.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19873..19944
                     /locus_tag="VXB18_001297"
                     /pseudo
     CDS             19873..19944
                     /locus_tag="VXB18_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            20092..21030
                     /gene="msrB"
                     /locus_tag="VXB18_001298"
     CDS             20092..21030
                     /gene="msrB"
                     /locus_tag="VXB18_001298"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0382496.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            21088..22812
                     /locus_tag="VXB18_001299"
     CDS             21088..22812
                     /locus_tag="VXB18_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382497.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVKLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDVLVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22814..24562
                     /locus_tag="VXB18_001300"
     CDS             22814..24562
                     /locus_tag="VXB18_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382498.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLIRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24864..26123
                     /locus_tag="VXB18_001301"
     CDS             24864..26123
                     /locus_tag="VXB18_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0382499.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     KAVKEALTEMLQSGTTTFNDMYNPIGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26199..26334
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26373..26873
                     /locus_tag="VXB18_001302"
     CDS             26373..26873
                     /locus_tag="VXB18_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0382500.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26949..27317
                     /gene="rplL"
                     /locus_tag="VXB18_001303"
     CDS             26949..27317
                     /gene="rplL"
                     /locus_tag="VXB18_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0382501.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27504..27674
                     /locus_tag="VXB18_001304"
     CDS             27504..27674
                     /locus_tag="VXB18_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382502.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27674..27925
                     /locus_tag="VXB18_001305"
                     /pseudo
     CDS             27674..27925
                     /locus_tag="VXB18_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27912..28259
                     /locus_tag="VXB18_001306"
                     /pseudo
     CDS             27912..28259
                     /locus_tag="VXB18_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28252..28632
                     /locus_tag="VXB18_001307"
     CDS             28252..28632
                     /locus_tag="VXB18_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0382503.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            28645..28788
                     /locus_tag="VXB18_001308"
     CDS             28645..28788
                     /locus_tag="VXB18_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382504.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            28881..29468
                     /locus_tag="VXB18_001309"
     CDS             28881..29468
                     /locus_tag="VXB18_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0382505.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            29670..29807
                     /locus_tag="VXB18_001310"
     CDS             29670..29807
                     /locus_tag="VXB18_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0382506.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         8942 a         5493 c         6748 g         8892 t
ORIGIN      
        1 aagtattttt gatagaacat atatttagag ttcgaaatag aatgatgcag ataggtgaaa
       61 ttataattat tgttgcttct ataatattat ttattgatag tatattgagt ttgtaacaaa
      121 aggcttctct ataaaatcaa attttccaga tacctattga agcagattta tttcttcatc
      181 tttcttctac tacctttgtc actaaatttg acagacacat attgctgata caacctctct
      241 acctataatc tcacggttaa cctgaggcta gtttcatagt ttgctatttg attttcgttg
      301 ataaaaagaa tgctcctcca agatggaaga gcatttttta ttgtgattct tacacattta
      361 cttcctagtt ttgcaggaag tctagtatac cattttttaa aagaagagta aaaaagcaag
      421 ggtagtttct tttttgagaa ttgtctaaaa gtttgatata atggtagtta tggatagaat
      481 aagagtcagc aaaagggttg aaaagaagct tgctaagggg ctagttttac tagaatccag
      541 tgatcttgag aatgtcaatc ttaaggatca ggaagtagag gtgcagggtc aggaaggaaa
      601 ctttcttggg actgcctacc tttctcagca aaacaagggc ttgggctggt ttgtcagcaa
      661 agacaaggtg gccttcaatc aaactttctt tgaaacgttg tttagaaaag ccaaagaaaa
      721 gagaaacgct tactatcaag atgatttgac aactgccttt cgtctcttta atcaagaggg
      781 agatggcttt gggggtctga cagtggacct ttatggcgac tacgccgtct tttcttggta
      841 taactcttat gtttatcaga ttcgtcagac tatatcagaa gcctttagac aggttttccc
      901 tgaggtttta ggggcttatg agaaaatccg ctttaagggt tttgactatg aatctgccca
      961 tgtttatggt caagaagcac ctgacttttt cactgtttta gaaaatggtg tcctgtatca
     1021 agtctttatg aatgatggct tgatgacagg aattttccta gaccagcatg aggttcgcgg
     1081 tagtttagtt gacggcttgg ctatgggtaa atccttgctc aatatgtttt cctacacagc
     1141 ggctttttca gtagctgcgg ccatgggagg agctagccag acaacttctg ttgatctagc
     1201 caaacgttca cgagaattgt ctcaagcgca ttttcaggca aatgggctca gcacagacga
     1261 gcatcgtttt atagtcatgg atgtctttga gtatttcaaa tatgccaaac gcaaagactt
     1321 gacctacgat gtgattgtcc tagatccgcc tagctttgct cggaataaaa aacaaacttt
     1381 ctctgtggcc aaggattatc acaagttgat ttcccagagt cttgagattt taaatccggg
     1441 agggattatc attgccagta ccaatgctgc caatgtttcc cgtcagaaat ttacagaaca
     1501 aattgataaa ggctttgcag gaagaagtta ccagatttta aacaaatatg gtcttccagc
     1561 agattttgcc tataataaaa aagatgaaag tagtaattac ctcaaggtga ttagtatgaa
     1621 ggttagtaaa tgaaattaat cgtttcagta atgccaagaa gtttagagga ggctcaggct
     1681 ctggatgcca cgaggtacct ggatgccgac atcattgaat ggcgtgccga ctatctgcct
     1741 aaagaagcga ttttgcaggt agctccagcc atttttgaaa aattcgcagg ccgtgagttg
     1801 gttttcacgc tacgaactcg ctccgaaggt ggagaaatcg acctttctcc agaagagtat
     1861 atccatctaa tcaaggaagt tgcgcaattc tatcaaccag actatattga ttttgagtac
     1921 tatagctaca aggatgtttt tgaggaaatg ctggacttcc caaatcttgt tttgagttac
     1981 cataatttcc aagaaacacc tgagaacatg atggaaatct tgtcagagtt gacgatccta
     2041 aatccaaaac ttgttaaggt tgcggtgatg gctcacacgg agcaggatgt cttagacttg
     2101 atgaactata cacgaggctt taaaaccctc aatcctgaac aggaatatgt gaccatttct
     2161 atgggtaagg tgggcaaggt ctctcgtatc actgcggatg tgactggttc gagttggtct
     2221 tttgccagtc tggatgaggt tagtgcccct gggcagattt ctctagctag catgaaaaaa
     2281 atcagggaga ttttggatga agcttgatgg ctatacacgt ttagctgcag ttgttgccaa
     2341 tcctattaag cattctattt ctcccttcat ccacaataga gcctttgagg cgacagctac
     2401 caacggtgct tatgtggctt gggagattga agcgagtgac ttggcagaaa cagtggccaa
     2461 tattcgtcgc taccagatgt ttggcatcaa tctgtccatg ccctataagg agcaggtgat
     2521 tccttatttg gataagctga gcgatgaagc gcgcttgatt ggtgcggtta atacggttgt
     2581 caatgagaat ggcaatttaa ttggatataa tacagatggc aagggatttt ttaagtgctt
     2641 gccttctttt acaatttcag gtaaaaagat gaccctgctg ggtgcaggtg gtgcggctaa
     2701 atcaatcttg gcacaggcta ttttggatgg cgtcagtcag atttcggtct ttgttcgttc
     2761 cgtttctatg gaaaaaacaa gaccttacct agacaagtta caggagcaga caggttttaa
     2821 agtggatttg tgtgctttag agtatgtttc tgaactgcaa gcaaggattg ccgagtcgga
     2881 tttgctagtt aatgccacca gtgtgggcat ggatggccaa tcctctcctg ttcctgaaaa
     2941 catagtctta ccagaaactc tcttagttgc agatatcata taccaaccct ttgaaacacc
     3001 gtttttgaaa tgggctagaa gtcagggcaa tccagcagtc aatggtctgg gaatgttgct
     3061 ctatcaagct gcagaagctt ttcaactgtg gacaggcaag gaaatgccga cagaagagat
     3121 ttggcagtct ttaacagaaa aataccaata aagaaaggga gactctccta tgaaaatcag
     3181 aatcgatatt cctcatcatc cttatgatat tcagattgaa aaaggttgta tggcccaggc
     3241 tggtcagtgg ttgcgagaac tctggcaacc gcaaaaggta gtcattgtga cagataacca
     3301 tgtagcctct ctctatgcag agaaggtcaa gctcagccta gaagatgctg gttttcaggt
     3361 agctgttttt gatttcttag aaggtgaaga aagaaagaat ttaactactg ttcagaaagt
     3421 ctatgaattt ctagtcaagc aaggtctgac tcgtagcgat ggaatcgtgg ctcttggtgg
     3481 tggcgttgtt ggggacctgg ctggctttgt agcctctacc tatatgcggg gtattcactt
     3541 tgttcagatt ccgactagtt tgacagctca ggttgattct tctatcggtg gaaagacagg
     3601 cgttaacaca ccatttgcta aaaatatggt ggggaccttt gctcaaccag atggggttct
     3661 gattgatcca cttgttcttg aaaccctcgg aaaaagagag ttgattgaag ggatgggtga
     3721 agttatcaag tatggcttga ttgaggatcc agaactgtgg gctctcttga cggggctgaa
     3781 tggttctgtt gagagcattt tggaacatgc agagaccttg attgaacatt cttgtcaggt
     3841 gaagcgcaag atggtggttg aagatgagtt ggacaatggt attcgtcttt acctcaattt
     3901 tggccacact attggccatg ccatcgaagc gactgccggt tatggcaagg tcatgcatgg
     3961 agaggctgtt gccatgggaa tggtacagat ttccaagatt gctgaggaaa aaggcctcat
     4021 gccagctagc attacccaat ctatcacaga gatgtgtcag aaattcggct tgcctgttga
     4081 ctatgaaaat tgggaagttg acaagcttta tcaggctctt actcatgaca agaaagcgcg
     4141 tggtaacacc ttgaaattgg tcttggtgcc agagcttggt tcagcgacca ttcatccagt
     4201 ttctctggaa gagatgaaag actacttggt aaaataagga gagtgtatga gatatttaac
     4261 tgcaggagaa tcacacggcc cccgtctaac agctattatt gagggaattc cagctggact
     4321 tccattgaca gctgaggata tcaatgagga ccttagacgc cgtcagggtg gctacggtcg
     4381 tggtggtcgt atgaagattg agaatgacca ggttgtcttt acttcgggcg ttcgccacgg
     4441 gaagacgaca ggggcgccta ttactatgga tgtcatcaat aaggaccacc agaaatggct
     4501 ggacatcatg tctgcggagg acattgaaga ccgtcttaaa agcaagcgga aaattactca
     4561 tcctcgccca ggtcatgccg atttggttgg ggggattaag taccgttttg atgatttgcg
     4621 aaattctttg gagcgttcat cagctcgtga aaccaccatg cgggtggcag ttggtgcagt
     4681 agccaaacgc ctcttggctg agctggatat ggagattgcc aaccatgtcg tggtctttgg
     4741 tggcaaggaa atcgatgttc ctgaaaatct gacagtcgct gaaattaagc aaagagctgc
     4801 ccagtctgaa gtttttattg tcaaccaaga acgagaacag gaaatcaagg actatattga
     4861 ccaaatcaaa cgtgatggtg ataccatcgg tggggttgtg gagacagtcg tcggaggcgt
     4921 tccagttggt cttggttcct atgtccaatg ggatagaaaa ttggatgcaa gattggctca
     4981 agctgttgtc tctatcaatg cctttaaagg ggtggaattt ggtcttggct ttgaggctgg
     5041 ttatcgtaaa ggcagccaag ttatggatga aattctctgg tctaaagaag acggttatac
     5101 tcgccgtacc aataatctag gtggttttga aggtggtatg actaatgggc aacccatcgt
     5161 tgttcgtggg gtcatgaaac ccattcctac tctttataaa cctcttatga gtgtggatat
     5221 cgaaacccat gaaccttaca aggcaaccgt ggagagaagt gatccgactg ctcttccagc
     5281 tgcaggaatg gtcatggaag cagttgtagc aacggttctg gcgcaagaaa tcctcgaaaa
     5341 attctcatca gataatcttg aggaactaaa agaagcggta gccaaacacc gagactatac
     5401 aaagaactat taaggagttc ctatggcaaa aacaatctat atcgcaggtc ttgggttgat
     5461 tggagcctct atggcacttg gtatcaaacg cgatcatcca gattatgaaa ttttaggtta
     5521 taatcgtagt caagcttcga gagatatcgc cttgaaagaa ggcatgattg accgtgcaac
     5581 ggatgatttt gctagttttg ctcctttggc agatgtcatt atcctcagct tgccaatcaa
     5641 acaaactatt gctttcatta aggagttggc caatttggat ttgcgagaag gcgttattat
     5701 ttcagatgct ggttcgacca agtcaaccat tgtggatgcg gcggagcagt atttggctgg
     5761 caagtctgtt cgctttgtcg gggcccatcc catggctggt agtcacaaga caggggctgc
     5821 ttcggcagat gtcaatcttt ttgaaaatgc ctattatatc tttacacctt caagcctgac
     5881 aagtcaggac acgcttaagg aaatgaagga tctgctttca ggtcttcatg ctcgttttat
     5941 cgagattgat gccaaggagc atgatcgtgt cacttctcag attagccatt ttcctcatat
     6001 tttggcttct agtctcatgg agcagactgc ggtctatgct caagagcatg agatggcaag
     6061 gcgctttgcg gcaggtggtt ttcgagatat gacccgaatt gcggaaagcg agccaggaat
     6121 gtggacctcc attctcttgt ccaatagcga gaccattctg gatagaattg aggatttcaa
     6181 ggaacgtttg gaagtgattg gtcaggccat tagtaaggga gatgaagagc aaatttggaa
     6241 cttttttaac caagcgcgtg aacaacgcca gaccatggaa atccataagc gtggtggtgt
     6301 ggatagctct tacgacctct atgttgacgt tcctgatgaa gaagatgtca tcctgcggat
     6361 tttggaactg ctacgtggaa cttccttggt taacatccac atcaacgagg aaaatcgtga
     6421 ggatattcac ggaatcctac aaatttcatt taaaaatgct caagacttgg aaagagctga
     6481 gcatctcata acagaaaata ccgactatac agtcgtcatc aaataaggag aagaacatgt
     6541 caaatattta cgatagtgca aacgaactca gtcgcggtct acgcggatta ccagaataca
     6601 aggctgttaa agcagctaaa gatgcgattg cagcagatgc tgaggcaagc aaaatcttta
     6661 cggaatatct tgcctttcaa gaggaaattc aaaaactagc acagacaggt caaatgccag
     6721 atgcgtcctt ccaagctaag atggaaggct ttggtaaaca gattcaagga aatagcctct
     6781 tgtcagaatt ctttaccaag caacaacaat tggccattta cctttctgac attgaaaaaa
     6841 ttgtttttga accagtttca gaattgctga aataagaaaa gaacgatcct aaagtcagga
     6901 atttttaagg aatttctggc tttttatgat aaaataggta aaagtattgc aagtatgagg
     6961 tccagtatga aactaaaaac aaatattcgc catttacatg gtagtatccg cgtcccaggt
     7021 gacaagtcta tcagccaccg ttccattatc tttggaagtt tggctgaggg tgagaccaag
     7081 gtttatgata ttctgcgagg tgaagacgtt ctttcgacca tgcaggtttt tcgtgacctt
     7141 ggtgttgaaa ttgaggataa agatggggtt attaccattc aaggtgtagg catggctggc
     7201 ttaaaagcgc cgcaaaatgc ccttaatatg ggaaattctg gcacctcgat tcgcctgatt
     7261 tcaggtgtcc ttgctggtgc agatttcgaa gtagagatgt ttggagatga tagtctttcc
     7321 aaacgtccta tggaccgtgt gacccttcca ctgaaaaaaa tgggcgtcag catttcaggg
     7381 caaactgaac gagacttgcc tccccttcgc ttaaaaggga cgaaaaacct aagacctatt
     7441 cattatgagt tgccaattgc ctctgcccaa gtcaagtcag ccttgatgtt tgcagcctta
     7501 caagctaagg gggagtcagt tattatcgaa aaagagtgca cccgtaatca tactgaagat
     7561 atgttgaaac aatttggtgg tcatttaagt gtggacagta agaaaatcac agtccaaggg
     7621 ccacaaaaat tgacaggaca gaaggtggtc gtaccaggag atatttccag tgcagccttt
     7681 tggttagtcg caggtttgat tgttccaaat tctcgtctag tgctgcagaa tgtggggatc
     7741 aacgaaactc gcaccggtat tattgatgtc attcgtgcca tgggtggaaa attggaaata
     7801 actgaaatcg atccagtcgc taaatcttct accttgactg ttgagtcttc tgacttgaaa
     7861 ggaacagaga ttggtggcgc tttgattcca cgattgattg atgaattgcc cattattgcc
     7921 ctgcttgcga ctcaagccca aggtgtaaca gttatcaagg atgctgagga gctcaaggtc
     7981 aaggaaacag accgtattca ggttgtggca gacgccttaa atagtatggg agcagatatt
     8041 actcctacgg cagatgggat gattatcaaa gggaaatcag ctcttcacgg tgctagagtc
     8101 aatacgtttg gtgaccaccg tatcggcatg atgacagcta tcgcagccct cttggttgca
     8161 gatggagagg tggagcttga ccgtgcagaa gccatcaata ccagctatcc tagtttcttt
     8221 gatgatttgg agagcttgat tcatggctaa ggtgttatta gggtttatgg gggctggaaa
     8281 atcgactatt gcaagaggct tggaccctaa ttaccttgat atggatgctc tgattgagaa
     8341 gcgcctaggt atgtccattg cgaatttttt cgctgaaaag ggagaagcag cctttcgtca
     8401 ggtagaatca gaagtcctag ctgatttact acaaacagac caagtcgtgt caactggagg
     8461 aggagtggtt atttctcaga gaaatcgtga cttactcaag actaatacag ataacatcta
     8521 cctgaaagca gattttgaaa ccctctacct acgtatcgta gctgataagg acaatcagcg
     8581 accgcttttt ctaaataata gcaaggaaga actagtagct atttttcaag aaagacaggc
     8641 ttggtatgag gaagtggcta gtcgggtttt ggatgtgacc aagctaagcc cagaggaaat
     8701 tatagaggaa ctaagatgaa aattgcttat ctaggtccca agggatcatt ttcacaccac
     8761 gttgtgcaga cagcttttcc tcatgaggaa ttgcaggctt ttgccaacat tacagatgtc
     8821 atcaaggctt atgagcaagg attagtgaac tattctgtgg tgccagttga aaattctatt
     8881 gagggtagtg ttcatgaaac cttggactat ctttttcatc aggctcacat ccaagcagta
     8941 gcagaaatcg ttcagcctat tcatcagcag ttgatggtgg ttccaggcca tactaagatt
     9001 gaaaagattt tttcacatcc acaggccttg gctcaaggaa agaaattcat cgatgaacaa
     9061 tatccagagg ctcaaatcga ggtaacagct agtacagctt atgcggcccg ttttatttcc
     9121 gaacatccag accagccctt tgcagcagtt gcacctagaa gttctgctga agaatatgga
     9181 ttggaactga ttgccgagga tattcaggaa atggaagcca atttcacacg tttctgggtt
     9241 ctaggagctg aaaatcctag tattcccttg caagcacaaa ctgaaaagat gagtttggcc
     9301 ttgacattac ctgacaacct tccaggtgca ctttataagg ccctgtcgac ctttgcttgg
     9361 cgaggaattg acttgacaaa aattgaaagt cgtccactca agacagcact gggtgaatac
     9421 tttttcatta tcgatgtgga ttataccgat aaggacttgg tccactttgc ccaaaaagaa
     9481 ttagaagcga ttggaatcca gtataaaatt ctgggtgcct atcctattta tccaatatca
     9541 gaccatggaa aggagagaag atgagtaaag aaaatccctt aagtcatcat gagcagttgc
     9601 gttatgatta tttgctaaaa aatattcact atctcaatga gagagaaaaa aatgagtttg
     9661 cctatttgca agaaaagcta actcttgcta ggggaaatag tagctctagc ttggaacaag
     9721 aaagagaaga gcaggttgac ttaccaagct atgcgaaccg gagtcgctca caatccaaat
     9781 cacaagcact ctctttccct ccaaaaaaga aaagacggaa gctccgtctt aaacgaattt
     9841 ttatggtgat tttttcactt ttggtctgtg tggctttggc catggtattc atgtttttgc
     9901 gtggttacca agatgctagc gcaaagaaaa ctgctgatgc ccgggcagct caagtagaag
     9961 tctttaatgg tcaggacact agagatggag ttaatatttt aatcatgggt actgatggtc
    10021 gaatcggcca gaacagtgtt gagacacgaa ctgactctat tatggtatta aatgtcgggg
    10081 gctcagataa gaaaatgaag ctagtcagtt ttatgcgtga taatttggtc tatatagatg
    10141 gttatagtca agtgattaat ggtagaaaac agacagataa caagttaaac gtagcctacg
    10201 agttaggaga acaagagggg caaaaagggg cagaaatggt tcgccaagtc ttaaaagata
    10261 attttgactt ggacattaag tactacgcct tggttgattt ccaggccttt gccacagcga
    10321 ttgacacgct tttccctgat ggggtgacga ttgatgctca attttcaaca ttgaatgggc
    10381 gtcccctaac agaagctaca gtcggagatg atttatatgc taccgagact gagtctccaa
    10441 cccaaaccat taaagtcgga aaacagcaga tgaatggctc gaccctgctc aattatgctc
    10501 gtttccgtga tgatgatgag gcggattacg gccgtacaaa aagacagcaa caagttttaa
    10561 cagcaatttt agagcaaatt aaagatccca ctaaactttt cactggttct gaagctcttg
    10621 gaaaggtttt tgctatgacc tcaaccaacg taccctatac tttcctccta acaaacggtt
    10681 tatctgtttt ggatggagca aaaaatggta ttgaaaaatt gacgattcca gaactgggtg
    10741 actgggtaga tgcctatgat gtttatggag gcttgggctt gctggttgat caaaacaaat
    10801 atcaaaccaa gctcgctcaa atgggcttga gataagataa tactcaatga aaattaaagt
    10861 gcaaactagg aagctagccg caggctgcta aaaacacagt tttgaggttg tagataagac
    10921 tgacgaagtc agttacctat acctacggca aggtgaagct gacgtggttt gaagagattt
    10981 tcgaagagta taagacagaa aaatcaaagt ttgatagcta tttggatagc agtcaggctt
    11041 tgatttttta cagtctgcaa tagattttca ccccttgttt gtggtataat gaaacgatac
    11101 gatagaaaga ataatgaaca atatgactga tttaaaagca attcaggctc gtagtctgga
    11161 gatggctgaa tattttgtgg ccttttgtaa agaacatgat ttgctctgtt atctctgtgg
    11221 cggaggcgct attggtaccc ttcgaaacaa gggatttatt ccttgggacg acgacctaga
    11281 cttttttatg cctcgtaaag attatgagaa attagcagaa ttatggcctc gttatgcaga
    11341 tgaacgttat ttcttgtcaa agagttacaa ggattttgtt gatcgtaatc tttttattac
    11401 cattcgtgac aaggaaacca cctgtatcaa gccttatcag caggatttgg atttgccaca
    11461 tggtctggcc ttggatgttt tgcctttgga ttattatccg aaagatccag ctgagcggaa
    11521 aaaacaggtt cgttgggcct tgatttattc actcttttgt gcgcaaacta ttccagaaaa
    11581 gcatggtgct ctcatgaaat ggggaagtcg cattttactg ggtttgactc caaaatctct
    11641 ccgttatcgc atctggaaaa aagctgagaa agaaatgact aagtatgatt tggctgattg
    11701 tgatggcatt acagaattat gctcaggtcc tggctacatg agaaacaagt acccaatcac
    11761 atcttttgaa gacaatcttt tcttgccatt tgaaggaaca gagatgccta ttccaatcgg
    11821 ctatgatgtc tatctcagaa ctgcttttgg ggattatatg acgcctccac cagcagacaa
    11881 gcaggtaccg catcatgatg ctgtcatcgc tgatatggat aagtcttata cagaatacaa
    11941 gggagaatat ggtggctaag aaaaaaatct tattttttat gtggtctttt tctcttggag
    12001 gtggtgcaga gaagattcta tcaaccattg tttcaaatct ggatccagaa aagtatgata
    12061 ttgatattct tgaaatggag cactttgaca agggatatga atctgttcca aagcatgtac
    12121 gcattttaaa atcccttcaa gattatcgcc aaaccagatg gttacgagct tttttgtgga
    12181 gaatgagaat ttattttcca agactggctc gtcgtttgct tgtaaaagat gattatgatg
    12241 ttgaagtttc ttttaccatt atgaatccac cactgttgtt ctctaaaaga agagaagtca
    12301 agaagatatc ttggattcat ggaagtattg aagaacttct taaggatagc tctaaaagag
    12361 aatcacatag aagccagttg gatgctgcga atacaattgt agggatttca aaaaagacca
    12421 gcaattctat caaggaagtt tatccagatt atgcttctaa attacagaca atctacaatg
    12481 gatatgattt tcagactatt ctagaaaaat ctcaagagaa gatcgatatc gagattgctc
    12541 ctcaaagtat ctgtactatc ggacggattg aggaaaataa gggttctgac cgtgtagtgg
    12601 aagtgatacg attattacac caagagggaa aaaactatca tctctatttt atcggagctg
    12661 gtgatatgga agaggaactg aaaaaacgag tcaaagagta tgggattgag gactatgtac
    12721 atttccttgg ttatcaaaaa aatccttatc agtatctatc tcagacgaaa gttcttttgt
    12781 ctatgtctaa acaagaaggt tttcctggag tgtatgtgga ggccttgagt ctgggactcc
    12841 cttttatctc tacggacgtt ggaggggctg aggaattatc ccaagaagga cgatttggac
    12901 aaatcattga gagcaatcaa gaggcagctc aggcgattac taattacatg acttctacct
    12961 caaactttga tgtcgatgag gctagccaat tcattcaaca atttacaatt acaaaacaaa
    13021 tcgaacaagt agaaaaacta ttagaggagt agcatggaaa ctgcattaat tagtgtgatt
    13081 gtgccagtct ataatgtggc gcagtaccta gaaaaatcga tagcttccat tcagaagcag
    13141 acctatcaaa atctggaaat tattcttgtt gatgatggtg caacagatga aagtggtcgc
    13201 ttgtgtgatt caatcgctga acaagatgac agggtgtcag tgcttcataa aaagaacgaa
    13261 ggattgtcgc aagcacgaaa tgatgggatg aagcaggctc acggggatta tctgattttt
    13321 attgactcag atgattatat ccatccagaa atgattcaga gcttatatga gcaattagtt
    13381 caagaagatg cggatgtttc aagctgtggt gtcatgaatg tctatgctaa tgatgaaagc
    13441 ccacagtcag ccaatcagga tgactatttt gtctgtgatt ctcaaacatt tctaaaggaa
    13501 tacctcatag gtgaaaaaat acctgggacg atttgcaata agctaatcaa gagacaaatt
    13561 gcaactgccc tatcctttcc taaggggttg atttacgaag atgcctatta ccattttgat
    13621 ttaatcaagt tggccaagaa gtatgtggtt aatactaaac cctattatta ctatttccat
    13681 agaggggata gtattacgac caaaccctat gcaaagaagg atttagccta tattgatatc
    13741 taccaaaagt tttataatga agttgtgaaa aactatcctg acttgaaaga ggtcgctttt
    13801 ttcagattgg cctatgctca cttctttatt ctggataaga tgttgctaga tgatcagtat
    13861 aaacagtttg aagcctattc tcagattcat cgttttttaa aaggctatgc ttttgctatt
    13921 tctaggaatc caattttccg taaggggaga agaattagtg ctttggccct attcataaat
    13981 atttccttat accgattctt attactgaaa aatattgaaa aatctaaaaa attacattag
    14041 aacgggggtg accaagtgat tgatgggaaa cgattattat ttagtttgac catagtcagt
    14101 tatgccttga cgctagtaag tggaattgtg tatctgttta ataataataa tgttagctta
    14161 ctttctactt tattgttctt gttggttagt agcttaattg cttgttggaa tgatatcaag
    14221 tattacttag tccattttat tttctattta accatttttg tatttctggt atcaagaccg
    14281 accattgatt attttaggga tggtgctttg gacacctatc atccaatagc ctatcgtttt
    14341 gcctttatag ttgtcatggt ttcgattctg ggcttgacaa caggaggcgt cctggctcgt
    14401 tacttcatag ctaggaagaa aataaaagta gcaaatatag gaaattctct aaaagaggtt
    14461 tatatcaagc ggttacgctt tgtatcacta ggagtttttc ttctaactta tcctttctat
    14521 ttcattcggt tatttgaacg gctcttgtat cgtttgcaga cttcctacta tgcctactat
    14581 gcaaattttg aaagtaaact gccttatttt acctacattt tgtctacctt tacggtctat
    14641 gcaatgtgta tgtatctggc aaccaagcca aagaaattgc aggccacagc agtgcttgtc
    14701 tcctttattg cagctaatac tattcatttg gcaattggga cacgaaatcc ctttatttta
    14761 agtattttat ttgcttttgt ttattacttt atgcgggagc aaactgaaaa aggaaaatgg
    14821 attgggttta aagaaaagtt agcgattttt gtaggttctc ctattctcat gttagcgatg
    14881 ggagtactca attatgtacg ggataatgtc caagtttccc atacaggttt ctgggatatc
    14941 ttacttgact ttatctataa acaagggact agttttggtg ttctggctcg aggttttcta
    15001 tttaacagta gcctccctta ccgagatttc cgtaatttta cttttggtcc tgttcttgat
    15061 tattttgcaa gggggagttt gggagccatt ttcggaggaa aagcctttga acatacaacc
    15121 aatagtgtgg aactagctat tgatagtaat agttatgccc acaatctatc ctatcttgtc
    15181 ttgaacaagg aatacttgaa agggcatggt atcggaagta gttatatcat ggagttgtat
    15241 accgactatg gtatgattgg agtctttctg cttagtttct tactcggcgt attatttata
    15301 gccatgctgc aagtagccta tcgctcaagg acaatcctat ttgctttatc cctactcatc
    15361 ttgaataatc tattctttat gccaagaagc agcttttcag aaagtttctt caatttattt
    15421 acaatgcaat tctggggaat tgttcttgtg attatatttg tagcaaaaat gcttacaaag
    15481 gaaaactagt atctactaaa caaaggagaa aaaatcatgt ttgaacatta ttcagtagct
    15541 gatttgtttg caaatcttta taaaaagcga aaagcaaata ttttagctct catcgcttta
    15601 tttgctctca ttgctgtacc atttacaatt aaagcagtta ggaataaaaa cactgtcaaa
    15661 gatacaacaa gttattcaac ttatcttatc tataaaatca ctcctccaaa agagtcggcc
    15721 aaaacgattt tgaatcatca aattggtggt tatagtgatt tttatgggaa attgattgat
    15781 ggtaatttga atggagctta tcttttcaat gatgtagaac ccagtgagtt gaaaaaaatt
    15841 gccagtgaat tagacacgac agaaacaacc ttgaaaaatt caacgaatga ctattggtgg
    15901 aaaaaattga ccgtctacta tatgattgac gatgcagggg ttggtgtgaa aattttgaca
    15961 tcaagtaaag atgccaatga cttgttagag aaaaaaattg atgggttgat tgagaaattt
    16021 aaacatgcct atgcaaatgt aaaaattgaa aaactggaaa ccatcaactc taaagaattg
    16081 aacgcaaatg gtgaaacagc gcttggctta aatgtgaaaa atctgattct tcgtttagtt
    16141 gttattggag tggtttgtgt gattttggtt gtgatgggaa atgtgttagt ttatttcttt
    16201 aatccaacaa tcaatagagt aggtgatttt tctcagtatc aaattgattt tgtaacagag
    16261 attacaacaa ttgctaacct agcagatgtt ttgtcataca aaaatactgg acaggaattg
    16321 accatcgtta gctcaaataa agctatccta gataaattga aacagagtca agaagcttta
    16381 aaaggaatgc attttgtaga tttacaggat gtatcatctc ttttggaaag agatacagtc
    16441 cttcttgttg aagagtacgg agtgactcgt tataagaaat ttgagcaaag tcttcaaatt
    16501 ctcagaaact taaatcgttc tatcctcggt gtagcaacct ttaaattata agtattctga
    16561 tgtatgaggt cttcaaaatc ggctaagagc tgattttgaa ggctttttct atctgtctgc
    16621 agaaattttc ttttggagtc tcctacagaa gttaccctag ggaaaatcta tccgtataga
    16681 ggagccttct tttgataaaa tcgtaaaaat ctagtataat agatagaact gaaagtatga
    16741 ggttactagc aatgaaaatg aaacaaatta gtgatacaac tttaaaaatc acgatgtctt
    16801 tagaggattt gatggatcgt ggaatggaga ttgctgactt tctcgttcct caagaaaaaa
    16861 cagaagagtt cttttatgct atcttggatg agctagagat gcctgatagc tttctggata
    16921 caggcatgtt gagcttccgt gtgactccaa aacctgataa ggtagatgtc tttgtgacca
    16981 agtcaaagat tgaccaaaat ctagattttg aagacttatc ggatttgcca gatatggaag
    17041 aattggctca aatgtctcca gatgaattta tcaaaaccct ggaaaaaagc atcgcagaca
    17101 aaaccaagga tgatatcgaa gccattcaat ctcttgagca agttgaagcc aaggaagaag
    17161 agcaagagca ggctgaacaa gaagctgaga gtaagaaaga accttacatc tactacatcc
    17221 tttcttttgc taagttggct gacttggtag cttttgccaa gacagtgact tttgaaatgg
    17281 aaacttctga actctacaaa atgaacgagc gctattattt gaccatttta gtggatattg
    17341 aaaatcatcc aagcccatat ccagcttggc tgttggcccg tatgcgcgag tttgcagacg
    17401 atagtgatat tagtcgctca gtcttacaag agtatggtca agtcttgatg agtcacgatg
    17461 cagtgctcaa tctgcaaaaa atcggctaat cctttctgga aagctatttt cagattttaa
    17521 gaagagcgaa tcgtctgatt cgttttttct ttttatactg aaatagtgat ttactataat
    17581 aggaattttc acaaaattct gttataatgg ctatattaga aaatttcgag gagataaaga
    17641 tgacagttaa aattgcttta ctaggatttg gtaccgttgc aagtggtgtg cctttcctcc
    17701 taaaggaaaa tggaggaaaa atcaatcaat cagcacattc agatatcaaa gttgctaagg
    17761 tattggtcaa ggatgaagat gaaaaaaatc gcttgcttgc agcagggaat gactttaact
    17821 ttgtaaccaa tgtggatgat attttatcag accaggatat tactatcgta gtggaattga
    17881 tggggcgtat tgagcctgct aaaaccttta tcactcgtgc cttggaagct ggaaaacacg
    17941 ttgttactgc taacaaggac cttttagctg tccatggcgc agaattgcta gaaatcgctc
    18001 aagctaacaa ggtagcactt tactacgaag cagcagttgc tggtgggatt ccaattcttc
    18061 gtactttagc aaattccttg gcttctgata aaattacgcg cgtgcttgga gtagtcaacg
    18121 gaacttccaa cttcatggtg accaagatgg tggaagaagg ctggtcttac gatgatgctc
    18181 ttgcggaagc acaacgtcta ggatttgcag aaagcgatcc gacgaatgac gtagatggga
    18241 ttgatgcagc ctacaagatg gttattttga gccaatttgc ctttggcatg aagattgcct
    18301 ttgatgatgt agcccacaag ggaatccgca atatcacacc agaagacgta gctgtagctc
    18361 aagagcttgg ttacgtagtg aaattggttg gttctattga ggaaacttct tcaggtattg
    18421 ctgcagaagt gactccaacc ttcctaccta aagcgcaccc acttgctagt gtgaatggcg
    18481 taatgaacgc tgtctttgta gaatctatcg gtattggtga gtctatgtac tacggaccag
    18541 gtgcgggtca aaaaccaact gcaacaagtg ttgtagctga tattgtccgt atcgttcgtc
    18601 gtttgaatga tggtaccatt ggcaaagact tcaacgaata tagccgtgac ttggtcttgg
    18661 caaatcctga agatgtcaaa gcaaactact atttctcaat cttggctcca gactcaaaag
    18721 gtcaggtctt gaagttggct gaaatcttca atgctcaaga tatttccttt aagcaaatcc
    18781 ttcaagatgg caaagagggt gacaaggcgc gtgtcgttat catcacacac aagattaata
    18841 aagcccagct tgaaaatgtc tcagctgaat tgaagaaggt ttcagaattc gacctcttga
    18901 ataccttcaa ggtgctagga gaataagatg aagattattg tacctgcaac cagtgccaat
    18961 atcgggccag gttttgactc ggtcggtgta gctgtaacca agtatcttca aattgaggtc
    19021 tgcgaagaac gagatgagtg gctgattgaa caccagattg gcaaatggat tccacatgat
    19081 gagcgtaatc tcttgctcaa aatcgctttg caaattgtac cagacttgca accaagacgc
    19141 ttgaaaatga ccagtgatgt ccctttggcg cgcggtttgg gttcttccag ctcggttatc
    19201 gttgctggga ttgaactagc caaccaactg ggtcaactca acttatcaga ccatgaaaaa
    19261 ttgcagttag cgaccaagat tgaagggcat cctgacaatg tggctccagc catttatggt
    19321 aatctcgtta ttgcaagttc tgttgaaggg caagtctctg ctatcgtagc agactttcca
    19381 gagtgtgatt ttctagctta cattccaaac tatgaattac gtactcgcga cagccgtagt
    19441 gtcttgccta aaaaattgtc ttataaggaa gctgttgctg caagttctat cgccaatgta
    19501 gcggttgctg ccttgttggc aggagacatg gtgaccgctg ggcaagcaat cgagggagac
    19561 ctcttccatg agcgctatcg tcaggacttg gtaagagaat ttgcgatgat taagcaagtg
    19621 accaaagaaa atggggccta tgcaacctac ctttctggtg ctgggccgac agttatggtt
    19681 ctggcttctc atgacaagat gccaacaatt aaggcagaat tggaaaagca acctttcaaa
    19741 ggaaaactgc atgacttgag agttgatacc caaggtgtcc gtgtagaagc aaaataaaga
    19801 atagaagata ggatggggaa actcttgacc agagggtttc atatcctttt tgtgaaaaga
    19861 agtttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa
    19921 cagtgttttg aggttgtgga tagaactgaa gaagtcagct caagacactg ttttgaggtt
    19981 gcagatagaa ctgacgaagt cagtaacata tatacggtaa ggtgacgctg acgtggtttg
    20041 aagagatttt cgaagagtat tagttaaaaa cgtgataaag gagaaataaa gatggcagaa
    20101 atttatctag caggtggttg tttttggggc ctagaggaat atttttcacg catttctgga
    20161 gtgctagaaa ccagtgttgg ctacgctaat ggtcaagtcg aaacgaccaa ttaccagttg
    20221 atcaaggaaa cagaccatgc agaaacggtc caagtgattt acgatgagaa ggaagtgtca
    20281 ctcagagaga ttttacttta ttatttccga gttatcgatc ctctatctat caatcaacaa
    20341 gggaatgacc gtggtcgcca atatcgaact gggatttatt atcaggatga agcagatttg
    20401 ccagctatct acacagtggt acaggagcag gaacgcatgc tgggtcgaaa gattgcagta
    20461 gaagtggagc aattacgcca ctacattctg gctgaagact accaccaaga ttatctcagg
    20521 aagaatcctt caggttactg tcatatcgat gtgaccgatg ctgataagcc attgattgat
    20581 gcagcaaact atgaaaagcc tagtcaagag gtgttgaagg ccagtctatc tgaagagtct
    20641 tatcgtgtca cacaagaagc tgctacagag gctccgttta ccaatgccta tgaccaaacc
    20701 tttgaagagg ggatttatgt agatattacg acaggtgagc cactcttttt tgccaaggat
    20761 aagtttgctt caggttgtgg ttggccaagt tttagccgtc cgatttccaa agagttgatt
    20821 cattattaca aggatctgag ccatggaatg gagcgaattg aagttcgttc tcgttcaggc
    20881 agtgctcact tgggtcatgt tttcacagat ggaccgcggg agttaggcgg cctccgttac
    20941 tgtatcaatt ctgcttcttt acgctttgtg gccaaggatg agatggaaaa agcaggatat
    21001 ggctatctat tgccttactt aaacaaataa aacagagagt ggggcttccc actttcttca
    21061 tttctagaat atgaatagaa gggatttatg aaacacctat tatcttactt caaaccctac
    21121 atcaaggaat caattttagc ccccttgttc aagctgttag aagctgtttt tgagctcttg
    21181 gttcccatgg tgattgctgg gattgttgac caatctttac ctcagggaga tcaaggtcat
    21241 ctctggatgc agattggcct gctccttatc tttgcagtaa ttggcgtttt agtggccttg
    21301 atagctcaat tttactcagc aaaggcagca gtaggctttg ctaaggaatt gacaaacgat
    21361 ctttatcgtc atattctttc cttgcccaag gatagcagag accgtctgac aacttctagt
    21421 ttggtcactc gcttgacttc ggatacctac cagattcaga ctggtatcaa tcaattcctg
    21481 cgtctctttt tgcgagcgcc cattatcgtt tttggtgcca tttttatggc ttatcgaatc
    21541 tcagctgagt tgactttctg gttcttagtc atggttgcca ttttgaccat tgtcattgta
    21601 gggttatctc gattggtcaa tcctctctac agtagtctca gaaagaaaac ggaccaactg
    21661 gttcaggaaa cgcgccagca attgcaaggg atgcgggtta ttcgtgcttt tggtcaagaa
    21721 aaacgagagt tacagatttt tcaaaccctt aaccaagttt atgctagatt acaagaaaag
    21781 acaggtttct ggtctagttt attaacacct ctgacctatc tgattgtcaa tggaactctt
    21841 ctcgttatta tctggcaagg ctatatttca attcaaggag gagtgctcag tcaaggtgct
    21901 ctcattgctc ttatcaatta cctcttacag attttggtgg aattggtcaa gctagccatg
    21961 ttgatcaatt ccctcaacca gtcctatatc tcagccaagc gaatcgagga agtctttgtt
    22021 gaggctccag aggatatcca ttcagagtta gaacaaaagc aagctaccag agataaggtt
    22081 ttacaagtcc aagaattgac ctttacctat cctgatgcgg cccagccttc tctgagatac
    22141 atttcctttg atatgactca aggacaaatt ctaggtatca tcgggggaac tggttctggt
    22201 aaatcaagct tggtgaaact cttacttgga ctttatccag tagacaaggg gaacattgac
    22261 ctttatcaaa atggacgtag tcctcttaat ttggagcagt ggcggtcttg gattgcctat
    22321 gtacctcaaa aggtcgaact ctttaaggga actattcgtt ccaacttgac tctaggtttc
    22381 aatcaagaag tatctgacca gaaactctgg caggccttgg agattgcgca agctaaggat
    22441 tttgtcagtg aaaaggaagg actcttggat gtcctagttg aggcaggggg gcgaaatttc
    22501 tcaggtggac aaaaacaaag gttgtctatc gcccgagcag tcttgcgcca agctccgttt
    22561 ctcatcctag atgatgcaac ctcggcactg gataccatta cagagtccaa gctcttgaaa
    22621 gctattagag aaaattttcc aaacacgagc ttaattttga tctctcaacg aacctcaact
    22681 ttacagatgg cggaccagat tctcctcttg gaaaaaggtg agttgctagc tgttggcaag
    22741 cacgatgact tgatgaaatc cagccaagtc tatcgtgaaa tcaatgcatc ccaacatgga
    22801 aaggaggact agaatgaaac gacaaactgt aaaccagacg ctcaaacgtt tagccgtaga
    22861 tttagcaaac catcccttcc tccttttcct agcctttcta ggaactattg cccaagttgg
    22921 cttatcaatt tacctaccta ttctgattgg gcaggtcatt gaccaagtcc tagtggctgg
    22981 ttcatcacca gttttttggc agatttttct acagatgctc ttggtggtaa taggaaatac
    23041 tctggtacaa tgggccaatc ctctcctcta taatcgtcta atcttctctt ataccagaga
    23101 tttacgagag cgaatcatcc ataaactcca tcggttaccg attgcttttg cggatcggca
    23161 aggcaatgga gagatggtca gtcgtgtaac cacggacatc gaacagttgg cagctggctt
    23221 gactatgatt tttaaccaat ttttcattgg tgttttgatg attttggtta gtattctagc
    23281 catgctccaa attcatctcc tcatgactct cttagtcttg ctgttgacgc cactgtccat
    23341 ggtgatttca cgctttattg ccaagagatc ctatcatctc ttccagaagc aaacagagac
    23401 gagggggatt cagacccagt tgattgaaga atcgcttagc cagcagacta taatccagtc
    23461 cttcaatgct caaacagagt ttatccaaag attgcgtgag gctcatgaca actactcagg
    23521 ctattctcag tcagccatct tttattcttc aacggtcaat ccttcgactc gctttgtaaa
    23581 tgcactcatt tatgcccttt tagctggagt aggagcttat cgtatcatga tgggttcaac
    23641 cttgaccgtc ggtcgtttag tgactttttt gaactatgtt cagcaataca ccaagccctt
    23701 taacgatatt tcttcagtgc tagctgagtt gcaaagtgct ctggcttgcg tagagcgtat
    23761 ctatggagtc ttagatagcc ctgaagtggc tgaaacaggt aaggaagtct tgaccagtga
    23821 ccaagttaag ggagctattt cctttaaaca tgtctctttt ggctaccatc ctgaaaaaat
    23881 tttgattaag gacttgtcta tcgatattcc agctggtagt aaggtagcca tcgttggtcc
    23941 gacaggtgct ggaaaatcaa ctcttatcaa tctccttata cgtttttatc ccattagctc
    24001 gggagatatc ttgctggatg ggcaatccat ttatgattat acacgagcat cattgagaca
    24061 gcagtttggc atggtgcttc aagaaacctg gctcacacaa gggaccattc atgataatat
    24121 tgcctttggc aatcctgaag ccagtcgaga gcaagtaatt gctgctgcca aagcagctaa
    24181 tgcagacttt ttcatccaac agttgccaca gggatacgat accaagttgg aaaatgctgg
    24241 agaatctctc tctgtcggcc aagctcagct cttgaccata gcccgagtct ttctggctat
    24301 tccaaagatt cttatcttag acgaggcaac ttcttccatt gatacacgga cagaagtgct
    24361 ggtacaggat gcctttgcaa aactcatgaa gggccgcaca agcttcatca ttgctcaccg
    24421 tttgtcaacc attcaggatg cggatttaat tcttgtctta gtagatggtg atattgttga
    24481 atatggtaac catcaagaac tcatggatag aaagggtaag tattaccaaa tgcaaaaagc
    24541 tgcggctttt agttctgaat aagccattct cttttgaaag tttatggacg aaaaaagttg
    24601 ccttcgagtg acttttttgt tacaatagct agaaaaattg tttactgtaa tactcaatga
    24661 aaatcaaaga gcaaactagg aagctagccg taggttgctc aaagcacagc tttgaggttg
    24721 tagataagac tgacgaagtc agctcaaaac actgctttga ggttgcagat agaactgacg
    24781 aagtcagtaa ccacacctac ggcaaagtga atctgaagtg gtttgaagag agtacaactt
    24841 gtcttttaaa aaaggagtct ataatgaaag tctttcagca tgtaaatatc gtgacttgtg
    24901 atcaaaattt ccatgtttat cttgatggaa tcttagcagt caaggattct caaatcgtct
    24961 atgtcggtca agataagcca gcgtttttag aacaagctga gcagattata gactatcagg
    25021 gagcttggat tatgcctggt ttggtcaatt gtcacaccca ttctgcaatg acaggtctga
    25081 gagggatccg agatgacagc aatctccatg aatggctcaa tgactatatc tggccagcag
    25141 aatctgagtt tactcccgac atgactacca aggcggtcaa agaagccttg acagagatgc
    25201 tccagtcagg aacaacaacc tttaacgata tgtataatcc cattggtgtg gatatccagc
    25261 aaatttatca ggtggtgaaa acttccaaga tgcgttgtta tttttctccg actctctttt
    25321 cttcagagac agaaacaact gctgagacta taagcagaac tcgatccatc atagatgaaa
    25381 tcttaaaata taaaaatcca aatttcaagg ttatggtagc acctcattct ccgtatagct
    25441 gcagtagaga cttgctggaa gcgagtttgg aaatggcaaa agagctaaat attccgctcc
    25501 atgtccatgt ggcggagacc aaggaggagt caggaattat cctcaaacga tacggcaaac
    25561 gcccccttgc ttttcttgaa gaactgggtt atttagatca tccgtccgta tttgctcacg
    25621 gggtcgaatt aaacgagaga gaaattgaac gcttggcatc ttctcaagtg gctatcgccc
    25681 acaatcctat cagtaacctc aaactggcat caggaattgc tccaattatc cagctccaaa
    25741 aagcgggagt agcagtcgga attgcgactg actcggttgc ttccaataac aatctagata
    25801 tgtttgagga aggaaggact gcagctcttc ttcagaagat gaaaagtggg gatgccagcc
    25861 agtttccaat cgaaacagct ctcaaggtac tgacaatcga aggggctaag gtccttggaa
    25921 tggaaaatca gataggaagt ctggaagtcg gcaagcaagc agattttctg gtcattcaac
    25981 cacaagggaa aattcatctc caacctcagg aaaatatgct gtctcacctg gtttatgcag
    26041 ttaaatctag tgatgtagat gatgtttata tcgccggaga acaagttgtt aagcaaggtc
    26101 aagtcctgac agtagaactt taaaagaaaa attacgaaaa attttaaaaa aagtttgcaa
    26161 aaatcttgca ttcttttttt gactatgcta tacttatata cggtttaaaa aaactgccta
    26221 agacagtagg ggagctcgac tcataaatat cctaccgagg acaagacgta tcatgtaaaa
    26281 agaagcgtat tgtactttcg tgtctaggtt tgggcgcgtt tttctttttg aaaaattccc
    26341 caagcaaaat aattacggag gtgaacacac taatgagtga agcaattatt gctaaaaaag
    26401 cggaactagt tgacgtagta gctgaaaaaa tgaaagctgc tgcatctatc gtcgttgtag
    26461 acgctcgtgg tttgacagtt gagcaagata cagttcttcg tcgtgagctt cgtggaagcg
    26521 aagttgagta taaagttatt aaaaactcaa tcttgcgtcg tgcagctgaa aaagctggtc
    26581 ttgaagatct tgcatctgta tttgttggac catctgcagt agcattttct aatgaagatg
    26641 ttatcgcacc agcgaaaatc ttgaacgact tttctaaaaa cgctgaagca cttgaaatta
    26701 aaggtggtgc aatcgaaggc gctgtcgcat ctaaagaaga gattcttgca cttgcaactc
    26761 ttccaaaccg cgaaggactt ctttctatgc tcctttctgt acttcaagcg ccagtgcgca
    26821 acgttgctct tgcagtcaaa gcggttgcag aaagcaaaga agacgcggct taatcttaag
    26881 ctacacagcg tagcctagct acgaaaaaaa ctattataaa atttaaaact tatttggagg
    26941 aaataacaat ggcattgaac attgaaaaca ttattgctga aattaaagaa gcttcaatcc
    27001 ttgaattgaa cgaccttgta aaagctatcg aagaagaatt tggtgtaact gcagctgctc
    27061 ctgtagctgt tgctgcagct gatgcagctg atgctggtgc tgctaaagat tcattcgacg
    27121 ttgaattgac atctgcaggc gacaaaaaag ttggcgttat caaagttgta cgtgaaatca
    27181 ctggtcttgg tcttaaagaa gctaaagaac ttgttgacgg tgcaccagca cttgttaaag
    27241 aaggcgttgc aactgcagaa gctgaagaaa tcaaagctaa attggaagaa gctggagctt
    27301 cagttactct taaataatag agtatcgcaa tttgattgcg gaatccctat ttaccagtct
    27361 ttgagagcga taagcgattg atagaaactg ataaattgat ttggtttcct gccaaaaatt
    27421 ctttggcagg atttttgttt taataaactt tcgggggtag acactagatt gtctacccct
    27481 ttttttgtgt ttcggaggta attatgcaaa aggaaggaca gtcatcacgt caattcgtga
    27541 agagtcatct catgactatc atgggagttg atattgtaaa agcaactcag ttagttgatg
    27601 aaatggaaca agtaggttta atccgatttg atgaatttgg aaatgttgga attttagtct
    27661 tggagggaca ataatgaagc gtattaccgc taatcaatat cagacatcag agcgttatta
    27721 taagctcccc aaacttttat ttgagagtga acggtataag aatatgaaac tggaggttaa
    27781 ggtggtttac tcagttttaa aagatcggtt ggagttgtct ttgagcaaag gttggattga
    27841 tgaggatggg gctatttatt tgatttattc caattcaaat ttgatggcac ttttaggctg
    27901 ttcaaagtca aaattactct ccatgtgagt ttgaagtaac atttttagat gattaccata
    27961 aaaaacacaa ctacccacta ttttacgagt cctatcttca aaacgttatg gaattccttg
    28021 aaagtcaaga cataaagaat ggggttgatg cctttgtaga tgatcatcaa aatctcgttt
    28081 ttgttttata tggacaaggc tatcgagccg agggaaaaga gggaatactt acaacccaag
    28141 taactgtaaa agcttatgat gaagacaaga aaccgattaa cttcgcaaat ttattagatt
    28201 ccttaatcgt ctcagaatat caaatggaac cgaatctttg ggaggtctcc catgattgat
    28261 ctctatctaa gtaaaaatag acaaagaaat caacttcttt tagatttctt ccaaaactat
    28321 ggcatagagg tatcttgtca ttcagtttct gaaatgacaa aggacaaatt aattgagatg
    28381 atgagctatt cttcagattg ttttgagttt ttatctccca atttattacg atttaagaac
    28441 cgtgacaatc taagattaac ggatttcgtt gagataattt taaaaaatcc tgaactaacc
    28501 atcagacttc ctcttgcggt ttcaaataag cgagtttatc caagtctgaa tttggaagag
    28561 gctagagctc tattgccaag agatacgaaa caattgattt acatggcgca aacacattat
    28621 ttatctaact aaaggagaag caatatggct gaacgatttt gggagaactt gtccattatt
    28681 ttggctgaaa gaaatatcag ctggattgag ttaaccagaa aaatgtttgc gggagagttt
    28741 cactatccaa gtgaattgaa tcgtttgtat caaaagattc gccactagaa gatggaacaa
    28801 tgaatgcctc aaagtccatg ggtagaaagg attgtgcagg tattagattt agattatgaa
    28861 gatttatttc ggaggtaact atgaaaagaa taattccagt ttatatattc caacaagtaa
    28921 atgtcctatt ggtatctcta tacttattga aatttctttg tatcggtgag ttaactatac
    28981 tacagattct ctatggttcg tcactcattt cttttttatg gatgtatggc caacgcaaac
    29041 aagcgcataa ggtcaatatg aaatctagga tgaaatggct tggtgttgaa tttgttagcc
    29101 tactgattat aagtctatgt tttagtctga ttcatgctca aggaagcacg aatcaagcaa
    29161 acttaattgg ccttcaacat caaattcctt ggttttcatt tttattgttc ttaatcaatg
    29221 cgagtatggt tgaagaattt ctgtatcgag aaattttatg gaatttggtc agaaaattag
    29281 atatcagagt tgctttgaca agtgttttat ttgccttagc acatcatcca ggaaccatta
    29341 tagcttggtg tttgtatgta tcgctgggga tgtttttagg gcttgtacgc tacaaattgg
    29401 acttatgggg cagtatgggg ctacatttgg tgtggagcct actagtttat agtttgctgc
    29461 ttttttaaaa taggtaacct gatttttagg taacttctaa aactaacttc cagttttggg
    29521 agagagatgg aagttacttt gaaaagttac ggaaacatta ttttctacgt gacaacattg
    29581 tatcattgct tgcattttac tgctggagag agtataatga aggtggataa agcacttaat
    29641 cccaaaaatt taaataggag gagttagcta tggcagaaga agtattaaat cttcaattag
    29701 tatctgttca agttgacgaa acagatgaag ttgatggaat gcgatttagt acattcagta
    29761 caaaccgttg cggtaactgg agtgctttta gttgggaaaa ttgttaattc atttaaattg
    29821 taaactttag ggattctctg aagttatgga tgtcgttcca atatgtgcac gttggaatgt
    29881 tagtgcttat atggggggaa cagaatcctc tcttgattga agacaagtta gccattaggc
    29941 tggtttgtct ctttgtcaac tgtagtgggt tgatataata gtattagtga gtgggataaa
    30001 agtttcattt agtttattca gtacaaattt aacgggtcaa gatttattga actgcacccc
    30061 aatagttaga cagaa
//
LOCUS       DAVKZI010000025        30020 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKZI010000025 DAVKZI010000000
VERSION     DAVKZI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30020
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.025"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(508..1494)
                     /locus_tag="VXB18_001311"
     CDS             complement(508..1494)
                     /locus_tag="VXB18_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0382507.1"
                     /translation="MGKSVAILMTTYNGERYLSQQIDSIRSQTFTNWTLFIRDDGSKD
                     KTIEVIQRYSKIDDRIRLVENPSKFHGAYYNFFNLIEYVKNNYQFDYYFFCDQDDIWK
                     EHKLEIQLLRFSKDDMPEMVYSDMSTIDASNNLIDISINKIMGIELPNINNLYFIQAY
                     IWGCTAGFNHALLEMVPSVDIDKDYLYIEKLAHDSYFAKFALEYGKVLFCPEQLVLYR
                     RHGHNVTTSHHFKLSPLNVFRKAILGFNELALTHARVYNQTLYMLKKASGKNPLSDRL
                     LEIQEVIKIGGLKGVRYFYQNRISRKQLVRTIGLYTIMLFGAYKKYIMKELL"
     gene            complement(1497..2216)
                     /locus_tag="VXB18_001312"
     CDS             complement(1497..2216)
                     /locus_tag="VXB18_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEV0382508.1"
                     /translation="MSIYKLCKDIERKTMSPAKKAMAKNDYFAFYVGRPLSYLLTVPF
                     VKTNITPNQISYLSIIPLIVGFIIMIFTTDFVVLLLAWFLFFLWNLLDGVDGNLARYR
                     EQYSKDGSVVDAMAGYVAMVLTYFGAGIVAAHLTDSDIYIILGALSGISLIFPRLVMH
                     KYINTVAQDESVSSIKDKSDFNTIKILALNMTSITGIPQVLLLLTILTNQWVLFTLVY
                     FTINFLLMIFSLYSLFKKENV"
     gene            complement(2203..3327)
                     /locus_tag="VXB18_001313"
     CDS             complement(2203..3327)
                     /locus_tag="VXB18_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0382509.1"
                     /translation="MFMKLLHFSEVGGGVDRYIKLYLKYSDKEHFKNIVVGSDQLNRQ
                     TYEQEYNIKFYHIDIYRSLSPIKLLRAIKQFRKILYLERPDIVYLHSTFAGVVGRLAS
                     MGLSCKVVYNPHGWSFKMDVSKIKQFVYKNIEKFLSYLTDKYILISKSEYEAAQSLKI
                     PLKKLTLVYNGVEIDEDFNENQINVLLPINKYVIGMIGRISEQKNPFFFVEFAKKLSE
                     IYSNLYFVIVGDGELRGRTEELIEEYGLRSSFFITGWVDNPEDYLAQFNQAVLFSKWE
                     GFGLAVAEYMKHKKPILITNVDGMSELVIDGESGFKVPLYNLEVTVDRSRSIIENREL
                     ANELGSAAFQRVRSTFEIKEKVSELENIFMSLREDDNVNI"
     gene            complement(3334..4701)
                     /locus_tag="VXB18_001314"
     CDS             complement(3334..4701)
                     /locus_tag="VXB18_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0382510.1"
                     /translation="MNGKIVKSSLVIIQSSLVILLTYLLSTVREAKIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDGLIESNEVVGEL
                     VAVSVLDKPDFQHDYLKIVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIRKMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            complement(4716..5405)
                     /locus_tag="VXB18_001315"
     CDS             complement(4716..5405)
                     /locus_tag="VXB18_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV0382511.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSIDKYGSY
                     GNYGNYGKNKK"
     gene            complement(5415..6107)
                     /locus_tag="VXB18_001316"
     CDS             complement(5415..6107)
                     /locus_tag="VXB18_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV0382512.1"
                     /translation="MKEQNTIEIDVFQLFKTLWQRKLMILLVALVTSAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVAVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFDKMK"
     gene            complement(6116..6847)
                     /gene="cps4B"
                     /locus_tag="VXB18_001317"
     CDS             complement(6116..6847)
                     /gene="cps4B"
                     /locus_tag="VXB18_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV0382513.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            complement(6849..8294)
                     /gene="cps4A"
                     /locus_tag="VXB18_001318"
     CDS             complement(6849..8294)
                     /gene="cps4A"
                     /locus_tag="VXB18_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0382514.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSTLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIKKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            8517..9038
                     /locus_tag="VXB18_001319"
                     /pseudo
     CDS             8517..9038
                     /locus_tag="VXB18_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9031..9198)
                     /locus_tag="VXB18_001320"
     CDS             complement(9031..9198)
                     /locus_tag="VXB18_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV0382515.1"
                     /translation="MKKRILSAGLTFTSALLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(9363..10970)
                     /locus_tag="VXB18_001321"
     CDS             complement(9363..10970)
                     /locus_tag="VXB18_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0382516.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNEDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENKKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKRVLAPWDAFCVELL"
     gene            11123..12607
                     /locus_tag="VXB18_001322"
     CDS             11123..12607
                     /locus_tag="VXB18_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0382517.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            12702..13184
                     /locus_tag="VXB18_001323"
     CDS             12702..13184
                     /locus_tag="VXB18_001323"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0382518.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(13251..13586)
                     /locus_tag="VXB18_001324"
                     /pseudo
     CDS             complement(13251..13586)
                     /locus_tag="VXB18_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(14038..16143)
                     /locus_tag="VXB18_001325"
     CDS             complement(14038..16143)
                     /locus_tag="VXB18_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0382519.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISDL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(16752..17732)
                     /locus_tag="VXB18_001326"
     CDS             complement(16752..17732)
                     /locus_tag="VXB18_001326"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0382520.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(17734..19986)
                     /gene="pbpX"
                     /locus_tag="VXB18_001327"
     CDS             complement(17734..19986)
                     /gene="pbpX"
                     /locus_tag="VXB18_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0382521.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(19990..20307)
                     /gene="ftsL"
                     /locus_tag="VXB18_001328"
     CDS             complement(19990..20307)
                     /gene="ftsL"
                     /locus_tag="VXB18_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0382522.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(20319..21269)
                     /gene="rsmH"
                     /locus_tag="VXB18_001329"
     CDS             complement(20319..21269)
                     /gene="rsmH"
                     /locus_tag="VXB18_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0382523.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            21435..21629
                     /locus_tag="VXB18_001330"
     CDS             21435..21629
                     /locus_tag="VXB18_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382524.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            21645..22187
                     /locus_tag="VXB18_001331"
     CDS             21645..22187
                     /locus_tag="VXB18_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0382525.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            22198..22440
                     /locus_tag="VXB18_001332"
     CDS             22198..22440
                     /locus_tag="VXB18_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382526.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            22451..22786
                     /locus_tag="VXB18_001333"
     CDS             22451..22786
                     /locus_tag="VXB18_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382527.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(22896..23897)
                     /locus_tag="VXB18_001334"
     CDS             complement(22896..23897)
                     /locus_tag="VXB18_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0382528.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(23957..25858)
                     /locus_tag="VXB18_001335"
     CDS             complement(23957..25858)
                     /locus_tag="VXB18_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0382529.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(25880..26173)
                     /locus_tag="VXB18_001336"
     CDS             complement(25880..26173)
                     /locus_tag="VXB18_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0382530.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(26173..26991)
                     /locus_tag="VXB18_001337"
     CDS             complement(26173..26991)
                     /locus_tag="VXB18_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0382531.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(26978..27757)
                     /locus_tag="VXB18_001338"
     CDS             complement(26978..27757)
                     /locus_tag="VXB18_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0382532.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(27772..28263)
                     /locus_tag="VXB18_001339"
     CDS             complement(27772..28263)
                     /locus_tag="VXB18_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0382533.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(28274..29464)
                     /locus_tag="VXB18_001340"
     CDS             complement(28274..29464)
                     /locus_tag="VXB18_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0382534.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(29476..29910)
                     /locus_tag="VXB18_001341"
     CDS             complement(29476..29910)
                     /locus_tag="VXB18_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0382535.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT         8998 a         6655 c         5141 g         9226 t
ORIGIN      
        1 taagtgtagt cgctggaata attttagata gttgattaat cattccactt atttctactt
       61 catttgaata ataagatagg tacctatagt tacttatcaa atctgtaata ttagaaaaac
      121 ttctacctga aaacaatacc actttctgaa tttcacgggt ataaagaaat agcataacaa
      181 gatttagaat cagaagaatg acatagatta tctttgaagg atttatttct ttcaattctt
      241 catacgaaat tccctccact ttaggcctgt acgacaattt tgtcaacaag gaaactataa
      301 taaatgtagc aacccctaac aatatcaaac caaaggtttt gaaatggagt tctgttcccc
      361 aaacatttct attaactaga gcacttgcaa tcgaaataaa ataagtgagt gttaaaatta
      421 ctgcaggttg aaaaaaatcc ccctcaaata atataaatgt aatgataatt aatagaaaaa
      481 tagatatgaa taagaaattt aaaagcatta taagagctct ttcataatat attttttata
      541 ggccccaaaa agcatgatgg tatataagcc gattgttctt acgagttgct ttcgagaaat
      601 tcgattctga tagaaatatc tcacaccttt taatcctcca attttgatta cttcctgaat
      661 ttcaagtagt ctatcactta aaggattttt tccagaagct ttttttagca tataaagagt
      721 ttgattatat accctagcat gtgtaagtgc caattcattg aaacccaata tagcctttct
      781 gaaaacattt agcggagata atttaaaatg atgactagtt gttacattat gtccatgtct
      841 tcgatacaag accagttgtt cagggcagaa caacaccttc ccatactcta gcgcaaactt
      901 tgcaaaataa ctatcatgag ccagtttttc tatatataaa taatctttat caatatcaac
      961 tgaaggaacc atctctagca atgcatgatt aaaacctgca gtacaccccc agatataggc
     1021 ttgaataaaa tacaaattat ttatgttcgg taattcaatc cccattattt tatttatact
     1081 aatatctatc aaattattac tggcatcaat cgttgacata tcagagtaaa ccatctctgg
     1141 catgtcatct ttagaaaatc ttaacagctg tatttctaac ttgtgctctt tccaaatatc
     1201 atcttgatca caaaaaaagt aataatcaaa ttgataattg tttttaacgt attcaattag
     1261 attaaaaaaa ttgtaataag ctccatgaaa ctttgaggga ttttcaacta atctaattct
     1321 atcatctatc ttagaatacc tctgtattac ttctattgtt ttatcttttg atccatcatc
     1381 cctaataaaa agtgtccaat tagtgaatgt ttgagaccta atactatcaa tctgttgtga
     1441 caaatatcgc tcaccattat aggtggtcat taaaattgca actgactttc ccatttctaa
     1501 acattctcct ttttgaataa tgaatacaaa gaaaatatca ttaataaaaa attaatcgtg
     1561 aaatatacta aagtaaaaag tacccactga tttgttaaaa tagttaatag cagtaaaacc
     1621 tgcggaattc ctgtaattga tgtcatgttt agagccagta tttttatagt attaaaatcg
     1681 gatttatctt taatgctact cacagactca tcttgagcta ctgtattgat atacttatgc
     1741 atcactaacc ttggaaaaat caatgaaatc ccagataatg cacccaggat tatatagata
     1801 tctgagtcgg ttaaatgagc agctactatt cctgcaccga aatacgtcaa caccatggct
     1861 acatagccag ccattgcatc tactacactt ccatccttcg agtattgctc ccgatatctg
     1921 gctaagttcc catctactcc atctagtaag ttccataaaa aaaatagaaa ccatgccagt
     1981 aataatacaa cgaaatcagt tgtaaatatc attattataa atccaacaat caaaggaatt
     2041 atagataaat aagatatttg attgggagta atatttgttt tcacgaaagg aactgttaaa
     2101 agataggata aaggtcttcc aacataaaat gcaaaatagt cgtttttagc cattgctttt
     2161 ttagcaggcg acatagtttt tctttcaata tctttacaaa gtttatatat tgacattatc
     2221 atcctctctt aaactcatga atatattctc taactctgac actttttctt ttatttcaaa
     2281 tgtagatcga actctttgga aagcagcact acctaactca ttggctagtt ctctattctc
     2341 aataatactt ctacttctat ctacagttac ttctaaatta tatagtggga ctttaaaacc
     2401 tgactcacca tcaataacca attctgacat cccatcaaca ttagttataa gaattggctt
     2461 cttatgtttc atatattccg caaccgccaa tccaaagccc tcccatttcg agaaaagaac
     2521 tgcctgattg aactgagcta aataatcctc tggattatcc acccaccctg ttataaaaaa
     2581 tgagcttcga agcccatact cttcaattag ttcttcagtt cgcccacgca attcgccatc
     2641 gccgacaata acaaaatata aattgctata aatctctgat aatttttttg caaattcaac
     2701 aaaaaagaaa ggatttttct gttcactaat acgaccaatc atcccaataa catatttatt
     2761 tatgggtaat aaaacgttta tttgattttc gttaaaatct tcatcaatct ctactccatt
     2821 atacactaaa gtcaatttct taaggggtat ttttaaagat tgagccgctt catattcaga
     2881 tttagagatt aatatatact tatctgtaag ataagacaaa aacttttcaa tatttttata
     2941 aacgaattgc ttaatcttag aaacatccat cttaaaagac catccgtgag gattgtatac
     3001 tactttacac gacaaaccca tagaagctaa cctgcctact acacctgcaa aagtactgtg
     3061 cagatatact atatcaggtc tttctagata caatattttt ctaaattgtt taatcgcgcg
     3121 taaaagcttt attggagaca agcttctata gatatcaatg tgataaaact ttatattata
     3181 ttcttgttca tatgtttgtc tattaagctg atctgatcct accacaatat ttttaaaatg
     3241 ttctttatct gaatatttta aatataactt aatataccta tcaactccac cgccaacttc
     3301 actaaaatga agcaatttca tgaacatatc cccctatttg gctccatcct tcatcaatac
     3361 taccttaact gtcttcaata aaatttcaat atctttccag attgtccaat catctatata
     3421 agccacatct aatttgacaa cttcatcgaa atttttgatt tcacttcgtc cactgacctg
     3481 ccataagcct gttataccag gtttaaaact tagccgacgt ttttgttctg gggtatagtg
     3541 ttcatactca tccactgttg gtggccgtgt gccaaccaaa ctcatatctc cctttagaac
     3601 attataaaac tgtggtagct cgtccaagct agtcttccgt ataaaacaac caattttcgt
     3661 gatacgagga tcatcgtcca ccttaaacat tccaccctgc atggtatttt gttccatgag
     3721 ttctcttttt ttcgcctcgg catctacaca catagagcga aacttataaa aagtgaactg
     3781 acgaccattt tttcctatac gcgtctgagc aaaaatagca gagcccccat cctttcgaat
     3841 caaaggaacc agtacaatac tgactaaacc acataatatc aacccgacca atgcacccac
     3901 gatatcaata atccgcttag caattacatg actagtctta taaaatgttg tagaaaaagt
     3961 cacaacgttt aatcctgcca tcttacgaat ttgcttgtta cgtgccaaac tacgatcaaa
     4021 agcatttaga ttgactgtta catcaattcc catcgtttca aactgagaga caagctctcc
     4081 aatattgtat ttttcacttg gaagattgat aaagacttca tcgaccacct catgagtcgc
     4141 aaagtttact atctccccct ctgctactat ctttaaataa tcatgctgaa aatctggttt
     4201 atctaagaca ctgacggcta ccaactcccc aacaacctca tttgattcta ttaatccatc
     4261 cagtaccttt tcgacacgag aagttgctgt aagtaggaga atcttcttac ttcctttaaa
     4321 gttgggataa gcccgcttcc aataccactt gataaatagg tttagcacat agactaagag
     4381 agcatgtaat gtgaggaagt aaatcatgcc tcgtctggaa atactaaatc gatcctctaa
     4441 gaaaaaatta gaaatactaa tcgctagtgc aaagaatagg atatatttca atgtctggac
     4501 aagttcaatc aaatatcccc ttttaaagaa atcctgtcca taatcactga tataaaagac
     4561 aaaataatgg aggatataaa gtgcaatagc tgttgttgaa acaatcttcg cttctctcac
     4621 agtactaagt agataagtca ataaaataac aagagaactc tggattatga ccaatgaaga
     4681 ctttactatt tttccattca tctctatccc ccgacctatt ttttattttt cccgtaattt
     4741 ccataatttc cataagaacc gtatttgtct attgaagtat cgaatttatt caacacaact
     4801 cccaaaaacg gcttccctgt gtgttccaac tgttcttttg ctttttgaat atcccgtcga
     4861 tttatttcac ctgcctccgt cactaaaata gaagcatcgc attttcgcgt aataatagcc
     4921 gcatcaatca cgacaccgac aggagcagta tctacaatga tgtagtcaaa atatttacgc
     4981 aaggtttcaa gcattgtact gaaattctta ctttgaagaa gagctgtcgg attcggtgac
     5041 acagagccag cctgaattac aaagagattt tcgatattgg tatcacaaag cccttgtgat
     5101 aggtctgtag ttcctgataa aaattctgtc aggcctgtaa tcttatccct tgctttaaag
     5161 acacctaaca taacagaatt gcgaatatct ccatcaatca gcagcgtttt gtatcctgca
     5221 cgcgcaaaag cccaagcgat attggtggaa gtcgttgatt ttccttctcc tagtttcaca
     5281 gaagtgatag aaaatacttt caaaccatct ccacttaact gtaggttcgt gcacaaagcg
     5341 ttataatatt cctctgcctt ttttacagaa tccaattttg cctgtgagat ttctaatgtt
     5401 ggcataactt cctcctattt cattttgtca aaatctggaa cgagccctaa aagtggaatt
     5461 ttcagtacat cttcaacatc ttcaggacgt ttcacacggg tgtcgagcaa ctcaatcaaa
     5521 agaacagcaa ttactgttac gactgctcct ccaagaaaac caaataagga attgcgtcga
     5581 acatttggag aagagggagt cgtagctggt cgcgcttctt caagtgtcgt tacatcagat
     5641 actcgcgtta cagcgacgat cttttctgca gcaacttctc gtagagaatt agcgatacga
     5701 ctggcttcct ctggctgttt atccttgaca gagattgaga cgatacgagt gtcagctggt
     5761 acagccactt gaactttgct ggctaacgtt tttgctggca tatccaactt caaatttgtc
     5821 gctacttttt ccaatgcatc ctgcgaaagg ataatctcac ggtagtcttt caccagataa
     5881 gttcctgcct gcaaatcctg atttgtcagc cccggcttgt ctccttgatt gcgattcact
     5941 acgtaaattc gcgtggtact cgtatattct ggcttaacaa taaaagtgct atatgcaaaa
     6001 gcccccgcac ttgtcacaag tgccactaat aaaatcatta gcttgcgttg ccacaaggtt
     6061 ttaaataatt gaaatacatc gatttctatc gtgttttgtt ctttcatcat ttctcctaaa
     6121 ttagttgatc cattacaatt tttcgaggat tgtctataaa aagttcctga gccttcgctt
     6181 ctccgtattt ttgggtaaca aggtcatatg cttctgccat atgaggaggt ctaccgtcta
     6241 gattgtgcat atcacttgca atgacatgga ccaaatcctg ctctaaaaaa tactgagctc
     6301 tttttttcat gaatttataa cgttcgccaa aaagtttggg tttgaggaca tgtgaactat
     6361 ttacttgcgt gtaacagccc atatcgatta gttctcgaac gcgtttttca ttattttcaa
     6421 gagcatcata gcgctcaatg tgggcaatga ctggagtaat tcccaacatc aagatcttgc
     6481 tcaaggcgct atgaatatcg cgataaggag tgttcatact aaactctatc aaggcataac
     6541 gactatcatt gagggtcgga atccgctttt ttcccagctt atccagaaca tctggtgtgt
     6601 agtaaatttc agccccgtaa gcaatgacta agtcactcgc cacttcctta gctatttccc
     6661 gaacctgaag aaagttttct gctatcttct cttccggagt ttcaaacatg cccttgcgac
     6721 ggtgagaggt agagacaatg gttcgcaccc cctgtctgta ggcttctgcc aagagagcct
     6781 tgctttcctc tcttgacttg ggaccgtcat ctacatcaaa aacgatatgc gaatggatgt
     6841 ctatcatttc atctaccctc catcacatcc tgtatagctg ctttaactac agctaaacta
     6901 ctatcatcta tttccatcac atagaggtta ctgtctggca ttgcataaga aggaagatcc
     6961 atccgacctg tacctttcaa gtcttgcgaa tttactttat aattcccccc actttccaac
     7021 tgagtattca ctaaatctat catagtctca atcggcatat ttgtttgaag agaatcctgc
     7081 aatccttgaa gaatactact atagtttttc aaaacctctg tagaagttaa cttcttaata
     7141 attgctacaa tgaccttttg ttggttgcga ccacggtcac ggtctccatc ggctagtgag
     7201 tagcgttcac gtacaaaacc tagagcctgc tcagagtcta gatggacatt ccctactggg
     7261 aaatggaact tcccatgtag agttgaaaac tcttgatcat tatgaacatc tactcctccc
     7321 aataagtcaa tcattttcaa gaaagaagtg aagttcaatc gcacatagta attgatatcc
     7381 actccataga gattttctaa ggtgtgaatg gacgaatcaa ctccataaat gcccgcatgg
     7441 gttaatttat ctttttgatt atttccacca tctgcgattg gtacataggc atcacgtggc
     7501 gttgtggtca agaggatttt cttggtatct cgattgacag tcatcaggat attgacatct
     7561 gatcgcgaca ccgaactaat aggaccatag gtgtcaattc cactaacata gatattgaaa
     7621 gactgattct tagacgtctt aggagcttct acttttttag tgaatccctt ggtataaatc
     7681 ttttttatct tcgatgcata gtctggatac tctgactcga tgatattttc aaagacacta
     7741 tttaagacaa tggccttagt ctcccctgca atcaaactct tgtaagctgc caagtaagac
     7801 gaactctgat cgaccgtcaa atcggtattc tgacttgact tgatatcagc tagtagtttc
     7861 tgaatatttt cattatcagt cccagtcggt gctgtcacac tcgtcagttg cgtaacattt
     7921 tcgatctcac tatctgctaa aacagcgaca ctgattgaat attctgagta attagaagtc
     7981 gcatttaaac gattggtcag tccaacaaac tgctgtactg caaagagcga cacagagctg
     8041 acaaggatag agaacaccaa cagaaaaata gtaaattttt cagctttttt atagataatc
     8101 aggagtagcc ctaccaaggc aactagtagg actaacgcag ttaccactag attaagatat
     8161 ctaaaagcaa ggatattgta cttaaagatt aagaacaata aaaaacaaac taacaataaa
     8221 taaatagtca acaaaactat attaacactt cgcttcactt tctgtgaacc tgatttttta
     8281 aaacgtctac tcatgattaa cacctataca ttgaacatca tacgattata tcactttttt
     8341 acggtaatgt ctacaccttt tttcactatc tgcatcttta agtatcttag tagacttccc
     8401 gcgaaacaaa aatatagtaa aatgaaataa gaacatgaca aatcaatcag gacagtcaaa
     8461 tcgatttcta acaatgtttt agaagcagag gtgtactatt ctagtttcaa tctaattatg
     8521 aacaagaccc agaaaaagta gccttatttc ttaagaattt taatagttta aagcacctag
     8581 cacctgttta gattgacgaa acaggattcg atacttattt ttatcgagaa tatggtcgct
     8641 cattaaaagg tcagttaaga agaggcaaag tatctggaag aagatatcag aggatttctt
     8701 tggttgcagg tctaacaaat ggtgagttaa tcgctccaat gacttacgaa gagacgatga
     8761 cgagcgactt ttttgaagct tggtttcaaa aatttctctt accaacatta aacacatcat
     8821 cggttattat tatggataat gtaagattcc atagactggg gaagctagaa cttttatgcg
     8881 aagagtttgg gcataaactt ttaccttctt cctccctact cacctgagta caatcctatt
     8941 gagaaaacat gggctcacat caaaaagcct cgtaaaaggt attaccaagt tgcaatacct
     9001 tttatgaggc tcttttgtct tgttcttgtt tcaattgact atattatcag cgtaatagtc
     9061 taatagatag ttaaatgtag ttggatttcc actaaaggtt gatgagtaag tttttgtatc
     9121 tgaacctgat tggccgcaag cagctaaaag caaagcagat gtaaaagtca ggcctgcact
     9181 aaggatacgc ttctttatgt tcgtcttctt tctccttaat agtgggaatt tgtaaagtta
     9241 attgaatttc gagaatgaag gtttataaac cttggttata aaaaacaaag gatttctgcc
     9301 ttttatacag tcctcccttg tttttatacg atttcaattt taaatttttc tgcaaaaaat
     9361 atttatagta attccacaca gaaagcatcc catggagcca agacccgttt ttcaagtact
     9421 tctttagccg cagtgttttc aatcaagaca gatttgactt ttccttctac tgtcaagtct
     9481 tgctcttcat tggacaagtt agccacaact aggaagcgac ggtcgccatc cttacgtata
     9541 taagcaaaga ccttatcagc cgtatcaagc aattcaaagt cagctcgaat tagccagcta
     9601 ttctccttgc gaatttggac cagtttctga taggtataga aaatagaatc tggatttgcc
     9661 agcgcttctt ggacattgat catctcgtaa tttggattaa ccgccaacca aggttgacct
     9721 gttgagaaac cagcgttttt gctctcgtcc cattgcatag gggtacgggc attgtcacgt
     9781 ccaataacac ggatactgtc catgatttct tcaatcggaa cacctttttc aagagcctca
     9841 cgcgcatagt tgagagattc aatatcttct acttgatcca gtgtttcaaa cggatagttg
     9901 gtcatcccaa tctcctcacc ttggtagata taaggagttc ctctcataag atgaagcaag
     9961 attgcaaagg ctttggcaga tttttcgcgg tattcttggt catttcccca gattgagacg
    10021 atacgaggga ggtcatgatt gttccagaag agggaattcc aaccgtcctc aactcctaac
    10081 tctgtctgcc atttgttgaa gatttctttt aacttagcga tattcagctc tttttgatag
    10141 tgccatttag gctgaccttc ctgatactga agaccgatat gttcaaactg gaagaccata
    10201 gacaattctt gcccctttgg atcagagtag agcttggcaa tctctggcgt tgctccccaa
    10261 gtctccccta ctgtcaagag atccttagct ccaaaggtcg cctgattcat ttccttgaga
    10321 tagggatgga gcataggacc attattgact accttctcat caggaatttt gccaatcatg
    10381 tcaataacat ccatacggaa accaccaata cctttatcaa tccagaagtt catcatctca
    10441 taaattttct ggcgaagttt tttattttcc cagttgagat ccggctgttt cttgctgaaa
    10501 aagtggagat agtattgacc agatttttca tcgtattccc aagcagatcc actaaaaata
    10561 gaatctaaat cgttaggctc atcccgccag atatagtaat ctcgctcagg gctattagga
    10621 ttttcacagg cctctacaaa ccaggcatgc tcatccgagg tatgattgac caccaagtcc
    10681 atgatgatac ggatatcacg cttcttagct tctgcaatca gttgatccat gtcctccatg
    10741 gttccaaaaa tagccgcaat cgcttgataa tcagcaatat catagccatt atcatccata
    10801 gggctgtcat aaacgggaga aagccaaatt gctgtgattc ctagcttggc tagatagtcc
    10861 aacttactgg taattcctgg caaatcgcca attccatctt cattactatc cataaaactc
    10921 tttggataga cttgatagac tacggcattg tgccaccatt tttcttgcat cttcttacct
    10981 cattattttc ataatctata gtctatgata gcacttttta aaattttgtg caagcgtttg
    11041 cttaatcttt ttaatttctt ttttagctcc gtagtttcct aacttccaat tttttattat
    11101 aatagagtcc agaggtaaaa aaatgaaaaa acaagctttt agttctgaac aatatttaaa
    11161 tctacaacgc gaccacatct tagagcgcat taaccaattt gacggcaagc tttacctaga
    11221 gtttggtggc aaaatgttag aagatttcca cgctgctcgt gtccttcctg gttatgaacc
    11281 tgacaacaaa atcaagctct tgcaagaatt gaaagagcaa gttgaggttg tgattgccat
    11341 taatgctagc aacattgaac attccaaagc acgtggcgac ttgggcattt cttatgacca
    11401 agaagttctt cgtttgattg acaaattcaa tgaattaggg atttttgttg gttccgttgt
    11461 cattacacaa tacgctggcc aacccgctgc agatgccttc cgcaaccaac ttgagaaaaa
    11521 cggaattgat tcttatcttc attatccaat caaaggatat ccgacggata tggatcacat
    11581 catttcccca gaaggcatgg gcaaaaacga ctacatcaaa accagtcgca acttgattgt
    11641 cgtaaccgct cctggacccg gttctggaaa attggcaacg tgtatgtcca atatgtacca
    11701 cgaccaaatc aatggcatca agtctggcta cgctaaattt gaaaccttcc ctgtttggaa
    11761 tcttcccctt catcacccag ttaacttggc ttatgaagct gccacagctg accttgatga
    11821 tgtcaacatg attgacccct tccatcttca aacctatgga gaaaccactg tcaactacaa
    11881 ccgtgatatc gaaatcttcc cagtgctcaa gcgcatgttg gaacgtattc tcggaaaatc
    11941 accatacgct tcaccgacag atatgggtgt caacatggtt ggtttcgcta ttacagatga
    12001 cgaggctgct gtcgaagctt ctaaacaaga aatcatccgc cgttactatc aaacagttct
    12061 tgacttcaaa gctgaaaaag ttggcgaagc tgccgtcaag aaaattgagt tgctcatgaa
    12121 cgacctcggt atcacacctg cagaccgtaa ggttgctgtc gttgcgcgcc aaaaagcaga
    12181 agaaactggt ggaccagccc tagcctttga attgccaaat ggggaaatca tcactggtaa
    12241 gaactcagaa ctctttggcc ctacagccgc tgccttgatc aatgccatca aaaaatcagc
    12301 tgacatcgct aaagaagtaa aactaatcga gcctgaagtt gttaagccaa tccaaggtct
    12361 taaaatcgat catctcggta gccgcaatcc acgccttcat tcaaatgaaa tcctgattgc
    12421 acttgctatc acagctacag aaaatcctga tgctgcccgc gctatggaag aactcggcaa
    12481 cctcaaagga agcgaagccc actcaaccat catcttgact gatgaagaca agaatgtcct
    12541 tcgtaaactg ggtatcaacg taacctttga cccatactac caatacgacc gcttatatcg
    12601 taagtaaaga tttcaacctc tctagcctcg gagaggtttt ctctctgtct caggaacaac
    12661 ctttatgata taatgagaga agaaaactga aaggatttac catgtcaaaa gaagttattg
    12721 tcgaaagttt tgaacttgac cacaccattg tcaaagcacc ctatgttcgc ttgattgggg
    12781 aagaaacagg accaaaagga gacattatct ccaattatga tattcgcttg gtgcaaccaa
    12841 acgaagactc tatccctact gccggccttc acactatcga gcacctctta gccaaactca
    12901 tccgtacccg cattgacggc atgattgact gttcaccatt tggttgccgc acaggcttcc
    12961 acatgattat gtggggacgt cacaccagtg ctaaaatcgc agctgttatc aaggattcgc
    13021 tcaaggaaat cgctgaaact actacttggg aagatgtccc agggacaacc atcgaatctt
    13081 gcggaaacta caaggaccac agcctcttct ctgctaaaga atgggcaaaa ctcatcttgg
    13141 aacaagggat ttcagatgat gcctttgaac gtcatgtgat ttaaaatcga gtaggggata
    13201 atctctagcc cctctcacac caccgtacgt gccgttcggc atacggcggt tcaactaact
    13261 tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg tttttcaagg
    13321 actggttttg atatagcacg tttaagtacc gacttctgag ctactaattg atagtggtcg
    13381 ccccagccag ataccttatc tgctatccat ttaggaaccc ctaacttaag caatccccat
    13441 aatcgtctcg attttttctt ccattgcttc cagataatca ctcgtaggcg agtatgcaag
    13501 cgctcatcta tgctagtgac tatacttttc atatttccca atgagaaata gtttatccat
    13561 cctcgaacag acaaattcag ttgctctcgt gatttacgca tataggctac gactaccttt
    13621 ttgaacttta gagtttgagg ccccttatcc gctatatacg ccttattatc acgttcctat
    13681 tcgtagagcc acgatttcgc tatcccttcc tctgacgatt cttatttcca gcgtcagact
    13741 taaaacggtc tatccccaga ccgttttaat ccgctacctc acgatagtca ggcttgggaa
    13801 tcactattgg gagcaccggt agcaggtacc caccgaggac ttacacctca gatatatagt
    13861 aaaatgaaat aagaacagga caaatcaatc aggacagtca aatcgatttc taacaatatt
    13921 ttagaagtag atgtgtacta ttctagtttc aacctactgt acgacatgcc cgtcgtacct
    13981 aaaaaggaac cagttttttt cagctggctc cttctttttt atcctcaaaa ttctgtctta
    14041 ggctttctca cgaataacca aaacgccatc ttccatatct gcttccagat gtttagcatc
    14101 taaatgatcc aagtggaagt ctgtcacctt atcacgaatt tcttgttcaa ccactcgacg
    14161 gagaggacga acccccatga cttcgtcgta accttcttct gtgatataat ctttagccgc
    14221 ttgactaact accaagtcaa tgtctttctt agccaaggtt tggttaactt cagccaacat
    14281 caaatctaca atcttagaaa ggtcttcctt agtcaagtgt gagaactcga tgactgcatt
    14341 aaagcggttg aggaattctg gacggaagaa gggtttcaaa cggtccatca attctggttt
    14401 atccgcatct tctgtcaagt tggcttcata gccaaatcca gcatttgagg tcgcaataat
    14461 gacagtgttc ttgaagttta ctgtatttcc ttgaccatct gtcaaacgac catcatctag
    14521 aacttggagg agaagggtaa taacttgagg gtcagccttt tcaatttcat ccaagagaat
    14581 gatagagtat ggattgcgac gaacacgttc tgttaaggta ttgctattgt catcataacc
    14641 cacatagcct gctgttgtac caattagctt agaaacagct gtacggtcac tgtattcaga
    14701 catatccaaa cggataatcg catcctgggt tccaaacata tcgagtgcca attgcttagc
    14761 aagctccgtc ttaccaaccc cagtagaccc tacaaagagg aagctgccga ttgggcgatt
    14821 tccttcatca aaaccagcac ggttacgacg gatagcacga gctacagctt ctacggcctt
    14881 atcttgacca atcaccttgt cttgcaagcg atgagccata tctttcaaac gttcgatatc
    14941 tgaagctccc atttgcgata ctgggatacc tgtcattcgt tccacagatt cagccacatc
    15001 gttgacactt gcagtcactt tcatatcttc tgtgtggttt tcgattttcc tttccaattc
    15061 tgcaatgcgt gttttatagt ttagagctgc ttcaaaatct tctgcttcaa ctgctttttc
    15121 ttgcttgtct ttttccgttt cgatttctcg ttcaacagca tgcacatctg ttactggatg
    15181 ttgagccgcc aagtgagcag ccgttacatc gacaaggtca atagccttat ctggcaagct
    15241 acgttgagga atgtattgaa cagaataatc caccgctgct ttcaagactt cgtctggcaa
    15301 gatgacattg tggtgttgtt gatagagatc acgaatgcct tgaagaattt taaaagtatt
    15361 ctctgctgaa ggagcattga ccttcacttc gttgaaacga cgagcaagag cagcattctt
    15421 caagatggtg ttacggtatt cgtcttgagt tgttgcccca atcactgtca attctccacg
    15481 agagagagct ggcttgagaa tatccgcaag tcctttagaa ccactgtctc caccagtgct
    15541 accagcacca agaatttggt gaatttcatc aaagaagagg ataatattcc ctgcttcttt
    15601 cacttcattg actaagtttt ggacattttc ttcaaagcta ccacggtatt gagtaccagc
    15661 ctcaagatct gagatatcaa tagaaataat ttccttgttc ttgatagcag caggaacatc
    15721 tccgttcaca atggcttgcg ctagaccttc gacaactgct gtcttaccaa cacctgcatc
    15781 tccgaccaaa acaggattgt tcttggtgcg gcgtgagagg atttcagatg tttcttgaat
    15841 ttccttgttt cgtccgataa caggatccaa cttgccctca cgcgcttctg ctgtcaagtt
    15901 tcgacctagt tttgcaagga caccgtcttg tttcatacct gatgcctgtt gtgacatttg
    15961 cacatcagtt tctgcatttc ctggtaattg accagtcgta cgatagtgag caaattcctc
    16021 aggtgtgact tcgcgcccat taattaagta acggcgattt tcagaactgt atcctcgcat
    16081 accacccatc aattggttaa ataaatcatc catgttatta aaattattaa agttgttatt
    16141 catattcttt acctcttttt gtttacttag ttatgattac tgatattgac tatctttgac
    16201 ctttgtttta aaaaatttag actagctaaa ccgctaccct acgtactatt tctggttttt
    16261 ctttttcaag caggagtaga ctatctttac ttctgaaaat ttctagatga aacatagacc
    16321 cacctctttc tattttactt taaataagtg ttctagtaag gctttcattt accttacgtt
    16381 cataatatac tacattggtc agaaaaggtc aagggttttg actttaactg accaatattt
    16441 ttttacactc ttcgaaaacc tcttcaaacc acatcagctt ctccttatct acaacctcaa
    16501 aaccgtgttt tgagctgact tcgtcagttc tatcaaccat ctcaaaactg tatattaaaa
    16561 cgaaataaga acaggacaaa tcaatcagga cagtcaaatc gatttctaac aatattttag
    16621 aagtagaggt gtactattct agtttcaaac tactatgttt tgagcagcct aaagttagct
    16681 ttctagattg ttctttgatt ttcattgtgt atttaaacac aaaaacaccc tgaaacatca
    16741 gggtgccatt cttacatcaa atataaaatt gcgagggtca ggagacttgc tagaagtccc
    16801 actccccaaa agaagaagtc aaccttccac tcgctccaag gatttccttt accagacaat
    16861 cccccaagct caaaatggtg atgtacaggc gtcatacgga aaatacgttt accacctgtc
    16921 agtttgaaat aactgacttg catcataaca gaagttgttt caaaaacata cacaattccg
    16981 ataatcaaga gagtccattc ttggtggaga gccatagaga tagctgccag catcccacct
    17041 agggccaaac ttcccacatc acccataaag accttggcag gcttatggtt aaagataaag
    17101 aaaccgagca aaccaccaat catggcaaga atcactagaa gaatatccat ctgaccttgc
    17161 acataggcaa taactccata ggcagacaaa ctaatcacaa cggaaatact agctaaaccg
    17221 tcaacaccgt ctgtcaagtt tactgcgttt gaaaaaccga ctagccagaa aagagcgaag
    17281 aaaatataga aaaatcccaa atgaactgga taaccaaaga cagacaggat atcgccaccg
    17341 cgctcataga aaagatagaa gataactcca cctagaagct gaagagctaa tttttgctta
    17401 ggattaagcc cctcattgat tttacgaaag accttgagaa agtcatctaa aaatccgacc
    17461 aagccataca agaccaagat gaacaaaatc attcccacat tattgctgaa ttggctacta
    17521 aatagggcga aaaagaaagc aaccaaaaca gaagtaatca agaaaaccaa acctcccatt
    17581 gtaggagtcc cagcttttgc ctgatgctgt ttgacatcct catgcatctg ctggcctgta
    17641 atttgcgcct ttctataaaa ttggataaag gccggaattt ctactaaagt tagtaaaaat
    17701 gtcacaattc cagcactgat ggaaataaac atattagtct cctaaagtta atgtaatttt
    17761 tttaatgtcc ttgatagctg tgttagcacg aacatcttgc ttctgcacag tagagcccga
    17821 accttgaaat tcaagttcta tattgagcca cttagcaagg gtctcagcag tctcctttgt
    17881 ccaaccatac atatctggaa cttcctctgc tttatcagat aagataagga cctgctgatt
    17941 cggggcaaga ttcttccctt cttcagcaga actgttttta atcttcgttc ctgttcccac
    18001 aacgatgggt tgtacaagat tgcgacgcaa ttcttctgct aaatcaccag gtgaaatatc
    18061 cttgacacta ggcataggat aaggactttg ttgacttact tgctccaaag ccttagctgt
    18121 tgtttgaaga ttgagagagt ctttcatagc tgaagcccgc tccaagatag gattggcaaa
    18181 ttctcccaac tgaatacctg aataatgttc aggttgttgg accgtcacat acaagataaa
    18241 atcaggattt tcagccggac tcatcgatac agccgagaaa atatagtcgg ttaacccgac
    18301 tagataacca ccatttttct cgtcagcaat ctgagccgta ccagacttga gggctacatt
    18361 ttgcccagga acagttacag ttggcttgcc tgtgctgtgg ttatacatgg ttccataaac
    18421 cggatccgtc cctaccaaaa ccatgttagt ccgagttaga ctagctgcat ctttagaaac
    18481 aggatttccc acaatttctt tttgagattt ccgagcagtt tgatcatttg gatcataaat
    18541 ggcactaata aatttaggct ccagcatgac accgtcatta gcaatagctg taaaggcacg
    18601 aatcatttgc gtctgggtca ctgaaatccc ttgtccaaat gagctttgcg caatgttgac
    18661 aatattatcc gcaggaagct gaccagcata ctcatccgtc aaaccgaaac gggtcggaac
    18721 accaaattta aaacgattaa gataatcaag ccaggtagca tctcccatct tttgctcaag
    18781 gagagtcatc ccaacgttac ttgagtgtgc aaaaccttga gaaaaagtca tcattctgcc
    18841 accagtcaat ccttcattaa cgtcccaatc tcgaatcgtg gcatctgcaa tttttaactc
    18901 actactatta aagacttctc ctcctggaaa ggtattatta tcaatagcag cagccaacat
    18961 catcactttc atagtggaac ctggctcata gttactttgg taaaggatat cacgccaaac
    19021 aaagtcctct gtaatgcctt cttttgtatc tgcatcaaag gtcggtcgtt gcgttgttgc
    19081 cagaatttcc cctgttttag cactgaccaa agtcgctgtc atgtactttc cttttacctt
    19141 ctcttgaaaa gcatccatct gggtttccat aaaggactgg agggggctgg aaatggttgt
    19201 ataaacatcc ttaccgtcca tcgttcgttg ggaaacttgt tctgttccag gtacaatatt
    19261 acccagacga tccttttcat aggtaataat gccgtctgtc cctgcaagaa tactgttcaa
    19321 ggaactctcc attccagagg ttcccagcaa gctcttgctt ccatcttcat tttcatggag
    19381 ctgagctagg ccgataaaac tagaagcaaa ttgtccgttt gggtaactac gattgggact
    19441 ggttgtaaaa tcaatcccct tgacctctgc agcttccaat tcttttttga tagacatcat
    19501 attggcatag gtaatcccat ttccctttgc tccaaaggaa acttgcttga gattaggttg
    19561 cgagagttgc tctcttacat aggattcttc catgtccaga tacttatgaa agacctctgc
    19621 aaccttgtta aattgtgttt tttctacgta aagaatctta cccgttgctg acttatagtt
    19681 ctcatcaatg accgcataga cattatagga ggttgcatcc tcagcaatcg ggactccatt
    19741 tcggtcataa atagtcccac gtttggcagg aactgtacgg gtggtttgat gaaccttctt
    19801 agcttccttc gctaaatctg ttccaaagcg agtgcctgtc ccaataatga ccgcaaaatt
    19861 gactaaaaaa atggcaaaaa caaagacaga taataaactc agactttttc caactctgcg
    19921 tctgttttca gccggcgatt tccgattttt ggtcgcataa cggattactc tttttgtcca
    19981 cttcatatct tactccgcta ttctaatatt ttcattgttt aattgcaaat cgtgtgaatt
    20041 ggcaatttct ttcaaacgtt ctgcacgtaa tagttcattg acctcttgct tggcatcgtc
    20101 caattcggtt ttcttttcct ctatctgcgc attgattttt gtcaaatcat tctgcacttg
    20161 caagagcttg gtctgcataa aaataatact aatggctaca ataagagtgg ttacagcaat
    20221 ggaaaagtaa aaagcttttt ccacacgcga aaaccgttta agttgcatct gtagtatttg
    20281 acctgttttt tccatttttt ctgccatctt tttccctctt acttgtgaat ttttctggcc
    20341 acgcgcaact tggctgagtg cgagcggtta ttggcttcta actcttccgc acttggcaag
    20401 attggcttac gggacaccaa ttccatcttg ggcttgagat catctgggat gaaaggcaag
    20461 ccttttggaa cttcaactgt tgaagcttcc ttgaacaatt gcttggtcaa gcggtcttct
    20521 aaggaatgaa aggtaatcac tgaaattcta ccatccagag ccaacatatc catagcctgc
    20581 tggatggact catctgccgc tcccagttca tcattgactt caattcgaat agcctggaaa
    20641 atctgcttag caggatgacc cttcttcttg agttccttgg caggtttgac caacttgata
    20701 atctctgcta actcagtcgt tgtctcaatc ggcttcactt cacgcgcttg ctcaatctta
    20761 cgcgcaatct gtttagagaa tttatcctca ccgtatttga agaaaatacg aaccaaatca
    20821 tgatagtcat agtgattaac cacttcatag gctgtcagac tagcatcctg attcatccgc
    20881 atgtccagtg gcgcatcctt tttataagaa aaaccacgct cacgctggtc caattgagga
    20941 ctagacactc ccaagtcata acaaattcca tcaatttcct gaacaccagc ttcgcgcaaa
    21001 cgtgcctgta aatgacggaa gttatccttg ataaaggtca ccattccctt ctcaatgtaa
    21061 ggtgccaagc gtttttgcgc attgtcaatg gcattctgat cctggtcaaa ggcatagaga
    21121 tggccttttt cacttaattt acttaataaa tactcgctat ggcctgctcc acccaaagtc
    21181 gcatcaacgt agataccgtc aggttttacg tcaagcatat caatcgtttc gtggagtaag
    21241 accgttacat gatgaaattc ttttgtcata tcttatctat tttaccacaa atccgaccag
    21301 cttgcacttg tcagacaaat aggacaagga gactactatt tcttcaaaaa atatgtcaaa
    21361 aatacttgac actttatgtt taaaagacta taatatagtc aaatatatac gacataaatc
    21421 agaaaggaga ccagatgaat cgtgtgaaag aatttcgcaa ggaattgggt atttcccagc
    21481 tcgaactcgc caaggatatc ggtgtctcga gacagactat caatatgatt gaaaacgaca
    21541 agtacaatcc aaccttggaa ctctgtctca atctcgcccg cagcctccaa actgacctca
    21601 acagtctctt ttgggaggaa gatttttaaa aaaggagcaa actcatgaaa aaagaaacct
    21661 tcactgaaaa actgatcaaa cgcacatacg gtatttctgg tccccttgac gaatacaaac
    21721 ggcgtgaggc cgatcgtatt gggaaccaag tctttatcat cctcttttat ctgatgattt
    21781 tcggaaatct tattccactc cttctggcct ataaataccc tcaagaagtg gctctaatct
    21841 atcctcctct gattttagtg attgccctca tcgctgctgg ctatgtcacc taccaaatga
    21901 aaaaaacagg gattacagct attgatccag acatgctgag cgagaaagaa agtaagcaac
    21961 tacattaccc aggtctgaaa gcaggtttgt tctttggtct atggatgttt tttataactc
    22021 ctcttctcag tatactcata gatgaaggtc aggactattt tcattctctt ctcactataa
    22081 gaaatggtgt atcaagtatt ctcggttcta ttttcttcgg agcgagcata cagttcctca
    22141 tctcccgtcg cattgcaaaa actaagaaaa atcaagatga ggattaggag gaaactcatg
    22201 aaaaaagaaa agaaacagtt acgttatcct ggtctgaaag caggttcgat ttatggaaca
    22261 gtgatatttt ttataattcc actcattgat accctaacaa gtgaaaatcc aaattttatc
    22321 agttctcttc taaatacaaa acatattttt aaaactatac tgggagcttt ctttttcgga
    22381 gtgatgatac atattgtcga ctcacttcgt attgcaagag ctaaaaaaga ccaggattag
    22441 gaggtgcctt atgaaatcac tagctagact actgatcatt catgttttta tcagtatttt
    22501 ccttttcttc gcccttactt caggagctat ttctcataca gttttactac tcctactcct
    22561 ctttcttcct gcgctcaata aaggacttga gaaaatacaa tcaaaacgga tacctgtcct
    22621 caacgcagcc ctcttctttc tcctcatatc ctttccacaa cttttaacca accctgtcca
    22681 atggaaattt tcaatattcc tagtcgtaac catcatttca agtttggcct acttctataa
    22741 cttttatcaa gtagttaaag aagtagatca aaaacagttg atttaggagc ttgctcccat
    22801 aatttctcat ttcataggca aataatccca cctagcttgt tctaggtggg attattttat
    22861 ttcttaacag aaattgcaag tcattttcct tcattttaga aagtcgactc tttccaattc
    22921 acactacaat ccaagacttg ttgcctttct tcttgattgc ggccttcaat ctgatcaatc
    22981 aaaatctttg tagcctgttg tccttcctca aaggagggct gaaccagcgt cgaaacactt
    23041 ggagaagaaa agcaagtcca ctccgtattg tcaaaaccaa tcaacccaac ttgcggcaag
    23101 ttataattca actctttgat aacggtaaag actagaggta gggcccaaca gttagggata
    23161 aataccagag ttttttcatc gggatcgatt tctttttgta aaaattcttt aatttgttcc
    23221 aaattcgtat gcttatcttc aatggttaga ctggcgtgac gcatattagc atctgttaaa
    23281 gcatccacaa aaccacttgc ccgctcaatc cgagtactca aacgactcgt atccgctgta
    23341 atcaagagaa aatgctcata acctttttcg atacaggact gggtcatgtc ataaacggca
    23401 tcatagttat tggttttaac ccagctagtc cggtgttcat agagctgact atcaaaaaag
    23461 accattttct tctttttctc atcgatgata cgagaatatt ttcggaaatt agaggtcggc
    23521 tgaataataa agccgtctac tcccaagaga agcatgcttt caatataccg gtcctcactc
    23581 tcttggctgt aattgctatt tcctatcatt acctggtagc cattctggct ggcgatatcc
    23641 tcaattccct taacaatttg gtttgagaaa ctgttggtaa tatcaccgat caaaacaccg
    23701 attaattttg ttcgtttgga gtttaagcta cgcgcaacaa tgctcggttt gtaatttgtt
    23761 tcatgaataa ctttttcaat cttttcacgt gtctcttggg acattttttc atatttcccg
    23821 tttaggtaaa atgacacggt tgttttcgag gtctgagcca tttccgcaat gtcttttatg
    23881 gtcagtttct tctccaatct aaaacacctc ctactaatac ttattataac atattcacta
    23941 ttcaaaatgc ctatttctag cactgcaagc gaatcattct ctcatttatt ttatcatata
    24001 ctagacattt tccacgcatt tttgttccgt caacgaggca caatttttca cctacacaaa
    24061 tatcctcgct taataacaga atcagcttgt ctgtttcgtc atttttcact tcaaaagcca
    24121 gagcattttc cacttcacga tcatctgtct ggtagacaga atgacggatg atttcaaaac
    24181 tctcatgcgc aatgatggta taatccagca tctgattctc aaagaattgg cgcttggtga
    24241 gtttgttact tctttcaagc tcattgtatt taggagaaat gatggtatct tccaaatcaa
    24301 aatcaacttc actccatagt ctcaactgat tgattttccc atcttgatag gtcacatcct
    24361 tgtcaaggat aaactgagtc aacgcctcat gctgaccttg acacctgatg tcatctacca
    24421 agagccagac atcctctacc aacatgagga tttttctctt gtgaagataa ggcaaatcag
    24481 gttctgctga ccaataagcc ccctcaatat aatgcactcc ctccctttct ttatggtgac
    24541 aaaacaggga gtgaggatag tattcatatt cccaggatcc cgtgattctt tccggagctt
    24601 tcccatctac aatgcaggtc gaatgactcc aagcactctt taagagataa cgttcatata
    24661 tctcccgata agaataacgc ccagcatcta tgaaaatagg ttggccttga tactgtaaac
    24721 aaaaactatt ctcgtcacta tggctatggg cacttcctag cggaccattt ttgaaaaata
    24781 gataacgatg ttcatcctta atgcagacat gtccagagtc ttcaaagatc atggacttag
    24841 gctgccaagc tctcctttca aattcctgca gtcgcttgac cttttctcgc cccaggaaca
    24901 agaggctaag caaatcgact ttaacatcca gaccgttaag aaggtcttcc ttgttcaaaa
    24961 ccacagcaga caggctcaaa atttctgtcg tttctgtaga atcgctatca ccaaaagcca
    25021 aagttcgtcc atctaagcct gtcatcattt gaatataggt cgccatcttt tccagcaact
    25081 ctcggtaact atcttgcaag tctggaagca agagacacaa atccagcaag gctttataaa
    25141 cctctacatg atagagaatc gactgttcaa actggcttcc atctcctaaa atctgtgtct
    25201 caatttgctg tttcaactcc tctgaagcaa aatggtaagc ttcttctaga tccatcttat
    25261 ctgaaaagaa atgatagata gcaagcatcg gaattgtttg taaaatcccc cagttactaa
    25321 gggtgtactt ggcgcgatag tagcttttca taaagtcaat ctgcttttct agactgacca
    25381 aaattttctc taattctttc tcctctagca agtcaaattt caagaggagc aagagtagtt
    25441 tcaaccaagt aaaggaacga atacccgtat ccaaggttct agtcatcaag gattgaggag
    25501 aaaattctct cacctgctca atccaatcaa atagaaagaa cttgcacttt tgaatatagt
    25561 ccttatctcc ttctaccaga taccctatca taaactgcaa gagatattct tgtcgattga
    25621 gcatataaga ccattctgga tcatcttcaa atacttgatc ccataccatc ggctggattt
    25681 gatggatttt tgaacaaggc tccatatccc aaggactatc aaacataaaa cgattgtcca
    25741 tcaagcgttc aagggaactc ttgactttct catagtcttt tgaacagtgg gacaagatat
    25801 aatcacgaca ttggtttcca tcgactcttt caaaaaattg tcttctttct tctttcatta
    25861 tctattacca gaaaaagaac tacttaaaaa gcagttcttt tgtctttccc attacacttt
    25921 ccttttctac atagatgacc acaccttttg caatctgcaa ggagaccaag tcatctttga
    25981 tagaaatgat ttttccatga attccagaca ataacaacac ttcatcacca gatgttaaag
    26041 aagctaaata ctcttgtcgt tgctccatct gtttgcgaag caacttttgc tgacgaatag
    26101 aatgaaagct tgacagtaaa aggggactca ctgccaagac aatcactatt ccataaaaca
    26161 atgttgtatc cattaagcta taatcttaag ccagcttccg ataattccga tgataactgt
    26221 taaaataacg agtttatatg ttgtccattt cttttctttg atcaagtagt aaactaaaag
    26281 tgtaaatagg gctggtagaa gagctggagc aaccttatca agcattccct gaatacttac
    26341 gatactttgt ttagcgtctg ctttaacttc ccctgcagca aaggtaatcg gcaccataat
    26401 cttaacagat gtcgctgcca aaccagcaat tacggttaca ccgataatat tggcaatacg
    26461 agaaatcgtt gccatctgtt cgcttagttt atcaatcaca gttgttccta gtttgtatcc
    26521 atacagacca gttgacaatt taatcgctgt taaaatcgta ttcatcgcaa ggaagaacaa
    26581 gattggaccg acaaccaagc cttcttgagc aaacgaagct gcgatggttg agaacaatgg
    26641 agctaaacag aattgagaaa gagaatcccc aatacctgcc aatggtccca tcaaggccat
    26701 cttgatgcta cgtgtttctt ttgttggtcg gccattttcc aacattacaa gatgcaagct
    26761 ggtaataaaa ggcaggaagt gtgggttggt attatagaat tcacagtttt cttccaaggc
    26821 ttggtagaaa ccttcctgat cctctccata gtgttttttc aaagcaggat acatcacatt
    26881 ggcatatccc aacccttgat agttactata gttaaatcca ttttgacaaa agaatgcccg
    26941 caaagacgtt ttaagataat cacgttttgt taatttgtta gatccagtca tcgtgtgctt
    27001 cctcctctac cacatgatcc gctgtttttg gcttgttata aaattcaatc aaagcaaaga
    27061 tagtacctac aattgcaata ccaattgttg ggatgtttag ataagctgca caaacatatc
    27121 ccaacaagac aaagggaatc aactctttct tagccatcac tgacaagatc atcgcaaaac
    27181 cgatagctgg gagcatttta ccagcaactg tcaaacctgt aagcaatact ggtggaatgt
    27241 agtctacgag tttcaacaag gtatccattg aaagggcacc caagcaaccc aaggtaaatc
    27301 caataaaggc aaacaaccaa attgttgcat ttagagtgaa cttgaatttc ttcaaattat
    27361 ggtttttcaa gtgcttcatc gccgtttcag gcgcaccagc acgtacagtg taggcgaaag
    27421 tttgtaagaa ttgaatcgcc acagcaatcg gagtagagag ggcaagagcc gcttctggac
    27481 tgactttacc agcactagtg atagccatca aggtaccaaa gataccaggt ccgattgggt
    27541 ttggtggaac agtacctcca gcaccaacac cgaatcccat ataagccaat tcaccaatag
    27601 ctcccattgc aagagcagta ggcaaatcac ctagaataat tccgacacca aatgacagaa
    27661 caatacatct attggtgtaa attcctaaca gcattccact aaaacagaaa gctgtccata
    27721 atccaattaa aatcgcttga aatacattaa tcgacataac gatctcctct tttaaatata
    27781 gtccataatg ttgacttgaa cagctccatc atttcctgtt ggagttgttt tcgtattaaa
    27841 tgttacttga tgagtttggc tcaattcctt gagggccgcc ttgtcctctt cacccaggaa
    27901 gatggagcgt gtcacttgct ctttaccagt agcattgtga atgttcccaa tattgatttc
    27961 tttgataggg acaccacctt ctaccaaggt taaagcgtcc ttcacatcct ttacaacgat
    28021 aaagatcgtt tgagcaggat tagccttgtg aatgatatca atcacctttt gcaaagggaa
    28081 gaaacgcatg gcaactgagt ctggcacaac tgttttcatc agagtttgtt gcatcttgtc
    28141 tgtgcttact tcgtcattgg caacaatgac cgtattacaa cctaggtatt ttacccaaag
    28201 ttgtccttgc ccatgaatca accgttcatc gatacgggtc ataataatat ttggcattgt
    28261 catatttctc ctcctaccaa tataggttcc agtctttgta gaaacggata agggcttcta
    28321 ggtaatagta gtcaccccag atattgcctt catccactcc tttacctgaa tgccatgagt
    28381 acacaccgtg gaggagactt gtcccaccag gggtaaattg atcatttgca taatgttcga
    28441 tcaaggaacg aagcatggca tgcatagcat gtttataaat atctttgtca gcatccacct
    28501 ctgggagatg ttttagcatt tcatgaatcc cacagacggc gatagctgtt gctgaagaat
    28561 ctcgtgattg atcactacca tcattaaaaa tcaaatccca ataggacaca tgatcttttg
    28621 gcagacgatt caagaaataa ttggtcacac ccttaaacaa gtcaaagcag gactcgtctt
    28681 ttaagtgacg ataagtcaaa ggaataccat agactcccca tgattgacca cgtgcccagc
    28741 atgaatcatc actataccct tgtctcgtta cacctttaaa gggttgacct gtctcaggat
    28801 caaaatagaa ggtgtggaag gacgaagcgt catcacggat tacattatta gctgaagcat
    28861 agaaatggct ttctgcaata tcgtagtatt tttgatcgcc tgtttcttga taagcaaaga
    28921 ataagagttg gatattgagc aagcagtcga taatcaaacg gtaatgctct ttcttgccca
    28981 agtctcccca agcttgaata aaaccacctt tttcttgata gcgttcaatc aacttatctg
    29041 cagctttcaa ggttgcttct ctagcctctc catctccatt tatcttatat tcagccatac
    29101 aagacggtgt gtacaagaag ccgagatcat gatgatccaa ttctactctc ttattgacac
    29161 gatccaggaa agaaagaaca tttttatgag cgatgttttt aaatgcatcc tgttgactgt
    29221 attcataagc caaccacagt tctcctgtcc agaaaccatt ggtccattcc gtgttatcca
    29281 tgattggata gacattatca aaggtagctg gcgtcgggaa atcttccttg aaatagtcaa
    29341 ggttgagttc taactgccga ataaccttat cgattgcctg gccgacttct tctttcgtca
    29401 gaagtggtac ttctaagaag cgctcaggcg attttatttt ttcaatcgta acctttttta
    29461 tcattctttt accctttaaa tacccgattc gaaatcttct tcctcttcct ctgcatccgt
    29521 tgaaaacaat tctttaccat ttacgactcc gccctgggcc gccactactg atttattaac
    29581 aacctcatca aagctatgag ccattctagc aaagactgct tccattaaca tggctaagtt
    29641 caaacccgag agaacattca ttgttttgac tggattttct cccattatgg tagaagaaac
    29701 cttgaatggc gatcctccca agagatcact taggattaaa acttcttctt catttgaaat
    29761 tgcaagtaag attttttgct tgagttcatc tgctgacatt ccttccacaa agtcaatcgc
    29821 ctccacattt tcttgattgc ctgcaatcaa ttgtaaagaa ctataaatcc ctgtagcaaa
    29881 atgtccatgc cctacaagta caattttcat cttttctcct ttcttgttta ggtttaccgg
    29941 tttactttat attccccatt gtaatccttt atttttatct tgtcaatagt ttttttaaaa
    30001 aaatattagc gctttcatta
//
LOCUS       DAVKZI010000026        29682 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKZI010000026 DAVKZI010000000
VERSION     DAVKZI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.026"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            304..2286
                     /locus_tag="VXB18_001342"
     CDS             304..2286
                     /locus_tag="VXB18_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0382536.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAANKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2586..7889
                     /locus_tag="VXB18_001343"
     CDS             2586..7889
                     /locus_tag="VXB18_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0382537.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSIWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(8056..10215)
                     /locus_tag="VXB18_001344"
     CDS             complement(8056..10215)
                     /locus_tag="VXB18_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0382538.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10212..10808)
                     /gene="recU"
                     /locus_tag="VXB18_001345"
     CDS             complement(10212..10808)
                     /gene="recU"
                     /locus_tag="VXB18_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0382539.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10874..11401
                     /locus_tag="VXB18_001346"
     CDS             10874..11401
                     /locus_tag="VXB18_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0382540.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11471..11800
                     /gene="gpsB"
                     /locus_tag="VXB18_001347"
     CDS             11471..11800
                     /gene="gpsB"
                     /locus_tag="VXB18_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0382541.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11821..12201
                     /gene="rnpB"
                     /locus_tag="VXB18_001348"
     ncRNA           11821..12201
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXB18_001348"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12286..13443
                     /locus_tag="VXB18_001349"
     CDS             12286..13443
                     /locus_tag="VXB18_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0382542.1"
                     /translation="MKKEFNLIATAAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13456..14850
                     /gene="mapZ"
                     /locus_tag="VXB18_001350"
     CDS             13456..14850
                     /gene="mapZ"
                     /locus_tag="VXB18_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0382543.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14926..16350
                     /gene="gndA"
                     /locus_tag="VXB18_001351"
     CDS             14926..16350
                     /gene="gndA"
                     /locus_tag="VXB18_001351"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0382544.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLNKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16362..17051
                     /locus_tag="VXB18_001352"
     CDS             16362..17051
                     /locus_tag="VXB18_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382545.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17149..18114
                     /gene="cbpC"
                     /locus_tag="VXB18_001353"
     CDS             17149..18114
                     /gene="cbpC"
                     /locus_tag="VXB18_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0382546.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPS
                     NGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            18133..19131
                     /gene="cbpJ"
                     /locus_tag="VXB18_001354"
     CDS             18133..19131
                     /gene="cbpJ"
                     /locus_tag="VXB18_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0382547.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            19253..20131
                     /gene="mvk"
                     /locus_tag="VXB18_001355"
     CDS             19253..20131
                     /gene="mvk"
                     /locus_tag="VXB18_001355"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0382548.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSYGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            20113..21066
                     /gene="mvaD"
                     /locus_tag="VXB18_001356"
     CDS             20113..21066
                     /gene="mvaD"
                     /locus_tag="VXB18_001356"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0382549.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            21053..22060
                     /locus_tag="VXB18_001357"
     CDS             21053..22060
                     /locus_tag="VXB18_001357"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0382550.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVFLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            22044..23054
                     /locus_tag="VXB18_001358"
     CDS             22044..23054
                     /locus_tag="VXB18_001358"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0382551.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIVDLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            23131..23829
                     /locus_tag="VXB18_001359"
     CDS             23131..23829
                     /locus_tag="VXB18_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0382552.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            23826..24821
                     /locus_tag="VXB18_001360"
     CDS             23826..24821
                     /locus_tag="VXB18_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0382553.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            24835..25467
                     /locus_tag="VXB18_001361"
     CDS             24835..25467
                     /locus_tag="VXB18_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382554.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQADVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            25468..25709
                     /locus_tag="VXB18_001362"
                     /pseudo
     CDS             25468..25709
                     /locus_tag="VXB18_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25634..25945
                     /locus_tag="VXB18_001363"
     CDS             25634..25945
                     /locus_tag="VXB18_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0382555.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLQLA
                     S"
     gene            25970..26236
                     /locus_tag="VXB18_001364"
                     /pseudo
     CDS             25970..26236
                     /locus_tag="VXB18_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            26386..26625
                     /locus_tag="VXB18_001365"
     CDS             26386..26625
                     /locus_tag="VXB18_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382556.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            26706..27527
                     /gene="cbpG"
                     /locus_tag="VXB18_001366"
     CDS             26706..27527
                     /gene="cbpG"
                     /locus_tag="VXB18_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0382557.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            27546..28568
                     /gene="cbpF"
                     /locus_tag="VXB18_001367"
                     /pseudo
     CDS             27546..28568
                     /gene="cbpF"
                     /locus_tag="VXB18_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(28696..29682)
                     /locus_tag="VXB18_001368"
                     /pseudo
     CDS             complement(28696..29682)
                     /locus_tag="VXB18_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         9056 a         5312 c         6797 g         8517 t
ORIGIN      
        1 ccataaaggg gaaactcttt tttgtctagt aaaaaacacc cattgggtga aaaaagaaac
       61 catccaggat ctaagctaag gcaaggattc tggatggttt ttagattagg ggtgaataat
      121 tggggtttag aaatagtatt aaaaattcct tgactatgtg atatagttga gggattttta
      181 aatgatattc atattttttg caaagatgtt gtttgaaaaa taattttcaa aaattctgaa
      241 aattctgttg acaactttct gaaaagagtc tataatggag agaaagtttt aaaggagaaa
      301 aggatgaaaa gttcaaaact acttgccctt gcgggcgtga cattattggc ggcgactact
      361 ttagctgcat gctctggatc aggttcaagc actaaaggtg agaagacatt ctcatacatt
      421 tatgagacag accctgataa cctcaactat ttgacaactg ctaaggctgc gacagcaaat
      481 attaccagta acgtggttga tggtttgcta gaaaatgatc gctacgggaa ctttgtgccg
      541 tctatggctg aggattggtc tgtatccaag gatggattga cttacactta tactatccgt
      601 aaggatgcaa aatggtatac ttctgaaggt gaagaatacg cggcagtcaa agctcaagac
      661 tttgtaacag gactaaaata tgctgctaat aaaaaatcag atgctcttta ccttgttcaa
      721 gaatcaatca aagggttgga tgcctatgta aaaggggaaa tcaaagattt ctcacaagta
      781 ggaattaagg ctttggatga tcagacagtt cagtacactt tgaacaaacc agaaagcttc
      841 tggaattcta agacaaccat gggtgtgctt gcgccagtta atgaagagtt tttgaactca
      901 aaaggggatg attttgccaa agcgacggat ccaagtagtc tcttgtataa cggtccttat
      961 ttgttgaaat ccattgtgac aaaatcctct gttgaatttg cgaaaaatcc gaactactgg
     1021 gataaggaca atgtgcatgt tgacaaagtt aaattgtcat tctgggatgg tcaagatacc
     1081 agcaaacctg cagaaaactt taaagatggt agccttacag cagctcgtct ctatccaaca
     1141 agtgcaagtt tcgcagagct tgagaagagt atgaaggaca atattgtcta tactcaacaa
     1201 gactctatta cgtatctagt tggtacaaat attgaccgtc agtcctataa atatacatct
     1261 aagaccagcg acgaacaaaa ggcatcgact aaaaaggctc tcttaaacaa ggatttccgt
     1321 caggctattg cctttggttt tgatcgtaca gcctatgcct ctcagttgaa tggacaaact
     1381 ggagcaagca aaatcttacg taatatcttt gttccaccaa catttgttca agcagatggt
     1441 aaaaactttg gcgatatggt caaagagaaa ttggtcactt atggggatga atggaaggat
     1501 gttaatcttg cagattctca ggatggtctt tacaatccag aaaaagccaa ggctgaattt
     1561 gctaaagcta aatcagcctt acaagcagaa ggtgtgacat tcccaattca tttggatatg
     1621 ccagttgacc aaacagcaac tacaaaagtt cagcgcgtcc aatctatgaa acaatccttg
     1681 gaagcaactt taggagctga taatgtcatt attgatattc aacaactaca aaaagacgaa
     1741 gtaaacaata ttacatattt tgctgaaaat gctgctggcg aagactggga tttatcagat
     1801 aatgtcggtt ggggtccaga ctttgccgat ccatcaacct accttgatat tatcaaacct
     1861 tctgtaggag aaagtactaa aacatattta gggtttgact caggggaaga taatgtagct
     1921 gctaaaaaag taggtctata tgactacgaa aaattggtta ctgaggctgg tgatgaggct
     1981 acagatgttg ctaaacgcta tgataaatac gctgcagccc aagcttggtt gacagatagt
     2041 gctttgatta ttccaactac atctcgtaca gggcgtccaa tcttgtctaa gatggtacca
     2101 tttacaatac catttgcatt gtcaggaaat aaaggtacaa gtgaaccagt cttgtataaa
     2161 tacttggaac ttcaagacaa ggcagtcact gtagatgaat accaaaaagc tcaggaaaaa
     2221 tggatgaaag aaaaagaaga gtctaataaa aaggctcaag aagatctcgc aaaacatgtg
     2281 aaataactgt tgcaaaatat aagaaaggat ttagtatttc tcttgaatgc tgaatccttt
     2341 tttacatttg taaagaaaga ttctaaatgt actgaccccc aaaagttgga gcctcttttt
     2401 gtcagaatag agaaaatttt tgttaatttt acttgtttcc tattgctttc tcagttatta
     2461 tttgttatat taaaagtata attattttta tttatcaggg ttaagcattg cactttcaga
     2521 ggaaggagta ttttttaaaa aggaaatgta aacgcttgct aaaaaatgaa aggatttaga
     2581 agtttatgaa taaaggatta tttgaaaaac gttgtaaata tagtattcgg aaattttcat
     2641 taggtgttgc ttctgttatg attggagctg cattctttgg gacaagtccg gttcttgcag
     2701 atagcgtgca gtctggttcc acggcgaact taccagctga tttagctact gctcttgcaa
     2761 cagcaaaaga gaatgatggg cgtgattttg aagcgcctaa ggtgggagaa gaccaaggtt
     2821 ctccagaagt tacagatgga cctaagacag aagaagaact attagcactt gaaaaagaaa
     2881 aaccggctga agaaaaacca aaagaggata aacctgcagc tgctaaacct gaaacaccta
     2941 agacggtaac tcctgaatgg caaacggtag agaaaaaaga acaacaggga acagtcacta
     3001 tccgagaaga aaaaggtgtc cgctacaacc aactatcctc aactgctcaa aatgataacg
     3061 caggcaaacc agccctgttt gaaaagaagg gcttgaccgt tgatgccaat ggaaatgcaa
     3121 ctgttgattt aaccttcaaa gaagattctg aaaagggcaa atcacgcttt ggtgtcttcc
     3181 tgaaatttaa agataccaat aataatgttt ttgtcggtta tgacaaggat ggctggttct
     3241 gggaatacaa aactccaggt aatagcatat ggtataaagg caaccgtgtt gctgctcctg
     3301 aaacaggatc aataaaccgt ctttctatca ctctcaagtc agacggtcag ctaaatgcca
     3361 gcaataacga tgtcaatctc tttgacacag tgactctacc agctgcggtc aatgaccatc
     3421 ttaaaaatga gaagaagatt cttctcaagg cgggctctta tgacgatgag cgaacagttg
     3481 ttagcgttaa aacggataac caagaggggg taaaaacaga ggatacccct gctgaaaaag
     3541 aaacaggtcc tgaagttgat gatagcaagg tgacttatga cacgattcag tctaaggtcc
     3601 tcaaagcagt gattgaccaa gccttccctc gtgtcaagga atacagcttg aacggacata
     3661 ctttgccagg acaggtgcaa cagttcaacc aagtctttat caataaccac cgaatcaccc
     3721 ctgaagtcac ttataagaaa atcaatgaga caacagcaga gtacttgatg aagcttcgcg
     3781 atgatgctca cttaatcaat gcggaaatga cagtacgctt gcaagttgtg gacaatcaat
     3841 tgcactttga tgtgaccaag attgtcaacc acaatcaagt cactccaggt caaaagattg
     3901 atgacgaaag aaaactactt tcttctatta gtttcctcgg caatgcttta gtctctgttt
     3961 ctagtgatca aactggtgct aagtttgatg gggcaaccat gtcaaacaat acgcatgtca
     4021 gcggagatga tcatatcgat gtaaccaatc caatgaagga tttggctaag ggttacatgt
     4081 atggatttgt ttctacagat aagcttgctg ctggtgtttg gagtaactct caaaacagct
     4141 atggtggtgg ttcgaatgac tggactcgtt tgacagctta taaagaaaca gtcggaaatg
     4201 ccaactatgt aggaatccac agctctgaat ggcaatggga aaaagcttat aagggcattg
     4261 ttttcccaga atacacgaag gaacttccaa gtgctaaggt tgttatcact gaagatgcca
     4321 atgcagacaa gaacgttgat tggcaagatg gtgccattgc ttatcgtagc attatgaaca
     4381 atcctcaagg ttgggaaaaa gttaaggata tcacagctta ccgtatcgcg atgaactttg
     4441 gttctcaagc acaaaaccca ttccttatga ccttggatgg tatcaagaaa atcaatctcc
     4501 atacagatgg tcttgggcaa ggtgttctcc ttaaaggata tggtagcgaa ggccatgact
     4561 ctggtcactt gaactatgct gatattggta agcgtatcgg tggtgtcgaa gacttcaaga
     4621 ccctaattga gaaggctaag aaatatggag ctcatctagg tatccacgtt aacgcttcag
     4681 aaacttatcc tgagtctaaa tacttcaatg aaaaaattct ccgtaagaat ccagatggaa
     4741 gctatagcta tggttggaac tggctagatc aaggtatcaa cattgatgct gcctatgacc
     4801 tagctcatgg tcgtttggca cgttgggaag atttgaagaa aaaacttggt gacggtctcg
     4861 actttatcta tgtggacgtt tggggtaatg gtcaatcagg tgataacggt gcctgggcta
     4921 cccacgttct tgctaaagaa attaacaaac aaggctggcg ctttgcgatc gagtggggcc
     4981 atggtggtga gtacgactct accttccatc actgggcagc tgacttgacc tacggtggct
     5041 acaccaataa aggtatcaac agtgccatca cccgctttat ccgtaaccac caaaaagatg
     5101 cttgggttgg ggactacaga agttatggtg gtgcagccaa ctatccactg ctaggtggct
     5161 acagcatgaa agactttgaa ggctggcaag gaagaagtga ctacaatggc tatgtaacta
     5221 acctctttgc ccatgacgtc atgactaagt acttccaaca cttcactgta agtaaatggg
     5281 aaaatggtac accggtgact atgaccgata acggtagcac ctataaatgg actccagaaa
     5341 tgcgagtgga attggtagat gctgacaata ataaagtagt tgtaactcgt aagtcaaatg
     5401 atgtcaatag cccactatac cgtgaacgta cagtaacgct caacggacgt gtcatccaag
     5461 atggttcagc ttacttgact ccttggaact gggatgcaaa tggtaagaaa ctttctactg
     5521 ataaggaaaa gatgtactac ttcaatacgc aggccggtgc aacaacttgg acccttccaa
     5581 gcgattgggc aaagagcaag gtttaccttt acaagctaac tgaccaaggt aagacagaag
     5641 agcaagaact aactgtaaaa gatggtaaaa ttaccctaga tcttctagca aatcaaccat
     5701 acgttctcta tcgttcgaaa caaaccaatc ctgaaatgtc atggagtgaa ggcatgcaca
     5761 tctatgacca aggatttaat agcggtacct tgaaacattg gaccatttca ggcgatgctt
     5821 ctaaggcaga aattgtcaag tctcaagggg caaacgatat gcttcgtatt caaggaaaca
     5881 aagaaaaagt tagtctcacc cagaaattaa ctggcttgaa accaaatacc aagtatgccg
     5941 tttatgttgg tgtagataac cgtagtaatg ccaaggcaag tatcactgtg aatactggtg
     6001 aaaaagaagt gactacttat accaataagt ctctcgcgct caactatgtt aaggcctacg
     6061 cccacaatac acgtcgtgac aatgctacag ttaacgatac aagttacttc caaaacatgt
     6121 acgccttctt tacaacagga tcggacgtct caaatgttac tctgacattg agtcgtgaag
     6181 ctggtgatca agcaacttac tttgatgaaa ttcgtacctt tgaaaacaat tcaagcatgt
     6241 atggagacaa gcatgataca ggtcaaggca ctttcaagca agactttgaa aatgttgctc
     6301 agggtatctt cccatttgta gtgggtggtg tcgaaggtgt cgaagacaac cgtactcact
     6361 tgtctgaaaa acacgatcca tatacacaac gtggttggaa tggtaagaaa gtcgatgatg
     6421 ttatcgaagg aaattggtca ctcaagacaa atggactagt gagccgtcgt aacttggttt
     6481 accaaactat tccgcaaaac ttccgttttg aagcaggtaa gacctaccgt gtaacctttg
     6541 aatacgaagc aggatcagac aatacctatg cttttgtagt cggtaaggga gaattccaat
     6601 caggtcgtcg tggtactcaa gcaagcaact tggaaatgca tgaattgcca aatacttgga
     6661 cagattctaa gaaagccaag aaggtaacct tccttgtgac aggtgcagaa acaggggata
     6721 cttgggtagg tatctactca actggcaatg caagtaatac tcgtagtgat tctggtggaa
     6781 atgccaactt ccgtggttat aacgacttca tgatggataa tcttcaaatc gaagaaatta
     6841 ccctaacagg taagatgttg acagaaaatg ctctgaagaa ctacttgcca acggttgcca
     6901 tgactaacta caccaaagag tctatggatg ctttgaaaga ggcggtcttt aacctcagtc
     6961 aggccgatga tgatatcagt gtggaagaag cgcgtgcaga gattgccaag attgaagcct
     7021 tgaagaatgc tttggttcag aagaaaacgg ctttggtagc agaagacttt gcaagtctta
     7081 cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt tgatggaaac ttatctagtt
     7141 tatggcatac atcatggggc ggaggagatg taggcaagcc tgcaaccatg gtcttgaaag
     7201 aagcaacaga aatcactgga cttcgttatg ttccacgtgg atcaggttca aatggtaact
     7261 tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa ggagcatacc tttactgcaa
     7321 ctgattggcc agataacaat aagccaaaag acattgattt tggtaagaca attaaggcta
     7381 agaaaattgt ccttacaggt actaagactt acggagatgg tggcgataaa taccaatctg
     7441 cagcggaact tatctttact cgtccacagg tagcagaaac acctcttgac ttgtcaggct
     7501 atgaagcagc tttggctaag gctcagaaat taacagacaa agacaatcaa gaggaagtag
     7561 ctagcgttca ggcaagcatg aaatatgcga cggataacca tctcttgacg gaaagaatgg
     7621 tggaatactt tgcagattat ctcaaccaat taaaagattc tgctacgaaa ccagatgctc
     7681 caactgtaga gaaacctgag tttaaactta gctctttagt ttccaatcaa ggtaagacgc
     7741 cagattataa gcaagaaata gatagaccag aaacacctga acaaatcttg ccagcaacag
     7801 gtgagagtca atctgacaca gccctcttcc tagcaagtgt tagtctagcc ctatctgctc
     7861 tctttgtagt aaaaacgaag aaagactagt atttagtaaa acctcttaac aagattacgg
     7921 aagcagtctc tatcttttcc aatgaggttt atagtacaga aaaagcctga gaagatgtct
     7981 tctcaggctt ttgttaagca cataaataca atagtgctat gacaaaatca cccagaaaaa
     8041 tctgggtgat aaatgttatg gttgtgctgg ttgaggattc tgattttgtt gatcaggggt
     8101 tgtatttgat tgttgcgtat tattgttagg attggtagtc gtactattat ttgtgcttgg
     8161 agtggttgag ctagactgtg aagttgaact atctgatgat gagcttgaac tttcagttga
     8221 tgggggttgt tgtggagcag gtgagttcca cgtagaacga gcaccatttt taaatacgaa
     8281 ttctccattt ctgtagagcc cctctggtat attccaatcc tctggattgc ttccttcaga
     8341 cagataggtc atcatagagc ggtaaacttt ggcagcgacc gtaaggccat tgcctacaag
     8401 tggtgtcaga cggttagaat agcctgtcca tacagccatt gaatatttac gcgtatagcc
     8461 agcaaatagt tcatcaggtg ctacaaattg agaggtcttg atgtggtttt caatttcctc
     8521 gtctgtatag ttagaggttc ctgttttacc agcctgaggg agccaagcaa gataggcatt
     8581 tcgtccagtt ccataactca agactgtttt catcatgtcg gtcatcatat aggctgtcgt
     8641 ttccttcatg gcacgagttc cgacattaga gaactctttt tcactcccat cactaaagac
     8701 gactttatgg atatacattg gtttatagta agttccacca tttgcaaagg cagcgtaagc
     8761 agcagccatc ttttcactac ttgctccata ttttttgtct gattcggttg tgttacttga
     8821 aatggcattt gagtagtgaa tacttgggta gtcgattccg agaccattta ggaaagtctt
     8881 ggcgcggttg agtccgacct tgtttagagt ttccacggct gggacgtttc gcgattgttg
     8941 cagggcgtat tgcaaggtga tgttgccaaa gtagccccta tcccagttat aaacaggggt
     9001 atttgtccca gggtagttat agggctcatc gtgaacgata gtagcagttg aatcgtagat
     9061 accgtactcc aaggcaggag catagtctgt gatcggtttc atagttgatc cccagtcgcg
     9121 gtttgtttct actgcttggt taattccgaa ggaaacatta cttgactgat ggcgtgctcc
     9181 tagctgggca atgactttac cgttagaaac atcaacaatg gtagaagcga cttgcaattc
     9241 atcgtctgga taggcaacgt attcgtctgt attgtaaata tcccacagat gtttttgagc
     9301 ttcttggtct acatttgtgt agacatccat cccagttgtg agcaggttat agcctgtttc
     9361 ttcttcaact tgattgatga cttccttgag gtaattatcc atgtaagcag ggtaattact
     9421 tgctgatttg agactttgta gtccatcagt aattggtgta ttgactgctt tctcatactg
     9481 ttcagcagag atgtagcctt gatttttcat ttcagataag accaagtttc ggcggtcttg
     9541 ggctgcttct ggatgtgaat aggggtcata ttggtttggt gcctgaggca ttccagccag
     9601 caaggctaac tgaggtaaac ttaaattatt gaggtcttta ccatagtagt tttgagctgc
     9661 tgtctgcatt ccatagttcc cattagacat gtagacctta tttatatagt aggtcaagat
     9721 ttcttgcttg gttgcttttt gttctaactg aatcgctaac caagcttcct gagccttacg
     9781 agaaatagtc tggtcggaag tcgaagttga aaagtaagtc aacttaatca actgttgagt
     9841 gagagttgat ccaccttgga gggaattgct ttgcagattg cgcaagaaag ctcccaggat
     9901 acggatggta tcaatccccc tgtggtcgaa gaagcgatgg tcttcgatag aaacgattgc
     9961 tttaaccaaa tctgtgggaa tatcattagc ttgggcattg acgcggcgtt cagaacccaa
    10021 gtcagcaatg agttgatttt tattgtcgta gattttacta gaagttgttg caactagttt
    10081 actctcggat aggctaggag ccttgctaac gtagtagaaa aaaactcctc cgcctaagac
    10141 aatggctgcg ataaccaagc ttaagaagct aatgctcaga tacttgatta ggcgcagaat
    10201 cgttggtttg ttcatcttgt tttaccacct aataaatgtt ctttgataac attgagataa
    10261 ggaatttgag ggaaggcacc agccttgatt tcatatccat attctcgaat atattcaagt
    10321 ggcattgatt tttgtccctt atcttgatga tagaagcgaa tcaaatcgaa tgccggcaat
    10381 aagtaggttt cttgctgaga agaaaagtga agaaggacaa agcagattcc ttgttgggca
    10441 aggacttgtt ccatatgctg aatctgatgt ggatgaaaat ttttcatcgg aatcgcacgt
    10501 ttttgttttg tttccttgac ttcaaagtcg atgtaatatc cattataaac gccagaatag
    10561 tccgtcgttg aagcttgtcg aaaataggct tcaacaatct tggcacgact tcgttgtgga
    10621 tagtccactt gtacgatttg aataggagtt ggtttcttat gtataacagc caagccctga
    10681 gacaaatagt agtcgttggt agcattgatc atcttttcaa aagacattcc tcgatttgcg
    10741 aaatttttgg gttgagaaag agatgtttgt cttttttgtg atgaaacttt atgtggatag
    10801 ttgaccataa ttctccttat tggtacaata acatcacttt attataccat aatttgcaca
    10861 gaaagggtta aaaatggcta cagctttggt tttaggctat tctgcttttg atttgggttt
    10921 attttctgat aaggatcctc gtcttaaatt gattaaaaaa gcgatacgta aagatttaga
    10981 ggctatggca gcagatgggg tgtcttggct tgtgtttaca gggactttgg gctttgaata
    11041 ttgggtttta gaggttgctc aggagatgaa aaccgaatac ggtttccagt tggccaccat
    11101 ttttgctttt gaaacccatg gggaaaattg gaatgaaggc aatcagatga aactgagtcg
    11161 ctttaagcag gtagactttg tcaaatatgc ctatcctcgc tatgaacaca aggggcagtt
    11221 aagagattac cagcagtttt tgctggaaaa cacgactagt tcctatcttt tttatgatga
    11281 agaaaatgaa acaaaactag cttattttta ccaaaagatg aaaaatcaag aggactattt
    11341 tataaagaga ttaacatttg atcaattaaa tgaacttgct gaaaattttt ccgaaaattg
    11401 aagctttgac cttgattttt gtttgccttt ttttatataa taatactagc aagcgagaat
    11461 ggagagagac atggcaagta ttattttttc agcgaaagat atttttgaac aggagtttgg
    11521 acgtgaagtc cgtggctata ataaagtaga agttgacgag tttttagacg atgtcatcaa
    11581 ggactatgaa acctatgctg ccttggtcaa gtcacttcgt caggaaattg cggatttgaa
    11641 ggaagaatta actcgtaaac cgaaaccttc accagttcaa gcagaacccc ttgaagcggc
    11701 aattacaagt tctatgacga attttgatat tttgaaacgc ctgaatagat tggaaaaaga
    11761 agtttttggt aaacaaattt tagataactc agatttttaa gtagttattt gagatgtgca
    11821 atttttggat aatcgcgtga ggagaattgc ttctcatgag gaaagtccat gctagcacag
    11881 gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa gcctagggac gagaaatcgt
    11941 tacggcagtt gaaatggcta agtccttgga taggccagag taggcttgaa agtgccacag
    12001 tgacgaagtc tttctggaaa cagagagagt ggaacgcggt aaacccctca agctagcaac
    12061 ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg tagtattctg actgctatca
    12121 gctagagctg ttagtggtag acagatgatt atcgaaggaa gtggtcctag tcacttctgg
    12181 aacaaaacat ggcttataga aaattgcata taggttgggg ctgagaaatt ttctcaacct
    12241 cattttttaa agtggacata tagaaaggtc ttgcaagact gtaacatgaa aaaagaattt
    12301 aatttaattg caactgcggc agcagggctt gaggctgtcg ttggtcgtga agtgcgagag
    12361 ttgggctacg attgtcagat tgaaaatgga cgtgttcgtt ttcaaggaga cgtgagagct
    12421 attatcgaaa ccaacctttg gctgcgggca gcagatcgta tcaaaattat cgtaggaacg
    12481 ttccctgcta agacttttga agagctattt cagggagttt tcgctttaga ttgggaaaat
    12541 tatttaccac ttggagctcg gttcccgatt tcaaaagcta aatgtgttaa gtccaaactt
    12601 cacaatgagc ccagtgttca ggctatttct aagaaagctg ttgtcaagaa attgcagaaa
    12661 cactatgctc gcccagaagg ggttcctctg atggagaatg gcccagagtt taagattgag
    12721 gtctctattc tcaaagatgt ggcaactgtc atgattgata cgaccgggtc tagcctcttt
    12781 aaacgtggtt atcgtaccga aaaaggtggc gctcctatca aggaaaatat ggcagcagcc
    12841 attttacaac tttctaactg gtatccagac aagcctttga ttgatccgac ctgtggttcg
    12901 gggactttct gtattgaggc agttatgatt gctagaaaga tggcgccagg tcttcgtcgc
    12961 tcttttgcat ttgaggaatg gaactggatc agcgatcgct tgattcaaga agtgcgcaca
    13021 gaagcggcta aaaaagtaga ccgtgagctt gagctggata tcatgggctg tgatattgat
    13081 gctcgcatgg tggaaattgc taaggccaat gctcaggcag ctggtgttgc aggagacatt
    13141 acttttaagc agatgcgcgt gcaggattta cgttccgata aaatcaatgg agtaatcatt
    13201 tccaatccgc cttatggtga acgtttgtca gatgatgcag gggtgaccaa gctctatgct
    13261 gagatggggc aagtatttgc accgctgaaa acttggagca aatttatcct gactagtgat
    13321 gaagcttttg aaagcaagta tggtagccaa gcagataaga agcgtaagtt atacaacgga
    13381 accttgaaag tggatctgta tcaatatttt ggtcagcgtg tcaaacggca agaggtaaaa
    13441 tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc aaaaaaaaga aggtcaagaa
    13501 ccgcaatttg attttgatga agcaaaagag ctaacagttg gtcaagctat tcgtaaaaat
    13561 gaagaagtgg aagcaggagt cttgcctgag gattccattt tggacaagta tgttaagcaa
    13621 cacagagatg aaattgaggc ggataagttt gcgactcgtc aatacaaaaa agaggagttc
    13681 gttgaaactc agagtctgga tgatttaatt caagagatgc gtgaggctgt agagaagtca
    13741 gaagcttctt cggaggaagt tccatcttct gaagacatct tactaccctt gcctctggac
    13801 gatgaggagc aaggcttgga tcctctattg ctagatgatg aaaatccaac agaaatgact
    13861 gaagaagtgg aagaggagca aaacctttct cgtctggatc aagaggactc agaaaagaaa
    13921 agtaaaaaag gctttatttt gaccgttttg gcgcttgtat cagtaattat ttgtgtcagt
    13981 gcttattatg tctaccgtca agtggctcgt tcgaccaagg aaattgaaac ttctcaatca
    14041 actacagcca atcaatcgga tgtggatgat tttaatacac tttatgacgc cttttacaca
    14101 gatagcaata aaacggcttt gaaaaatagc cagtttgata aactgaatca actcaagact
    14161 ttacttgata agctggaagg tagtcgtgaa catacgcttg ccaaatctaa atatgatagt
    14221 ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc aatttgagaa accagctatt
    14281 gtggatggtg tgttggatgc caatgccaaa gccaaatcgg atgctaaatt tacggatatt
    14341 aaaactggaa atacggagct tgataaagtg ctagataagg ctatcagtct tggtaagagc
    14401 cagcaaacaa gtacttctag ctcaagttca agtcaaacta gcagctcaag ttcaagtcaa
    14461 gcaagctcaa atacgacaag tgagccaaaa ccaagtagtt caaatgagac tagaagtagt
    14521 cgcagtgaag tcaatatggg tctctcgagt gcaggggttg ctgttcaaag aagtgccagt
    14581 cgtgttgcct ataatcagtc tgctattgat gatagtaata actctgcctg ggattttgcg
    14641 gatggtgtct tagaacaaat tctagcgact tcacgttcac gtggctatat cactggagac
    14701 caatatatcc ttgaacgtgt caatatcgtt aacggcaatg gttattacaa cctctacaag
    14761 ccagatggaa cctatctctt tacccttaac tgtaagacag gctactttgt cggaaatggc
    14821 gctggtcatg cggatgactt ggactactaa gcagtcgtta caaaattctt tcttttcaaa
    14881 agtaaaaatg ataaaataaa acaaatgaaa caagaggagt gtcaaatgac aaaagctaac
    14941 tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg cccttaatat tgaatctcgt
    15001 ggttacacag ttgctatcta caaccgtagt aaagaaaaaa cggaagatgt gattgcttgc
    15061 catcctgaaa agaactttgt accaagctat gacgttgaaa gttttgtaaa ctcaatcgaa
    15121 aaacctcgtc gtatcatgct gatggttcaa gctggacctg gtacagatgc tactatccaa
    15181 gcccttcttc cacaccttaa caagggggat atcttgattg acggaggaaa tactttctac
    15241 aaagatacca tccgtcgtaa tgaagaattg gcaaactcag gtatcaactt tatcggtact
    15301 ggggtttctg gtggtgaaaa aggtgccctt gaaggtcctt ctatcatgcc tggtggacaa
    15361 aaagaggcct acgaattggt ttcggatgtt cttgaagaaa tctcagctaa agcaccagaa
    15421 gatggcaaac catgtgtgac ttatatcggt cctgatggag ctggtcacta tgtgaaaatg
    15481 gttcacaacg gtatcgagta cggtgatatg caattgatcg cagaaagtta tgacttgatg
    15541 caacacttgc taggtctttc tgcagaggat atggctgaaa tctttactga gtggaacaag
    15601 ggtgaattgg atagctactt gatcgaaatc acagctgata tcttgagccg taaagacgat
    15661 gaaggccaag atggaccaat cgtagactac atccttgatg ctgcaggtaa caagggaact
    15721 ggtaaatgga ctagccaatc atctcttgac cttggtgtac cattgtcact gattactgag
    15781 tcagtgtttg cacgctacat ttcaacttac aaagaagaac gtgtatatgc tagcaaggtg
    15841 cttccaaaac cagctgcctt caactttgaa ggagacaagg ctgaattgat tgaaaagatc
    15901 cgtcaagccc tttacttctc aaaaatcatt tcatacgcac aaggatttgc tcaattgcgt
    15961 gtagcctcta aagaaaacaa ctggaacttg ccatttgcag atatcgcatc tatctggcgt
    16021 gatggctgta tcatccgttc tcgttttttg caaaagatta cagatgctta caaccgcgat
    16081 gcagatcttg ccaaccttct tttggacgag tacttcttgg atgttactgc taagtatcaa
    16141 caagcagtgc gtgatatcgt agctcttgcg gttcaagctg gtgtgccagt gccaactttc
    16201 tcagcagcta ttacttactt tgatagctac cgttcagctg accttccagc taacttgatc
    16261 caagcacaac gtgactactt tggtgctcac acttaccaac gtaaagacaa agaaggaacc
    16321 ttccactact cttggtatga cgaaaaataa gtaggtcagc catggggaaa cggattttat
    16381 tacttgagaa agaacgaaat ctagctcatt ttttaagttt ggaactccag aaagagcagt
    16441 atcgggttga tctggtagag gaggggcaaa aagccctctc catggctctt cagacagact
    16501 atgatttgat gttattgaac gttaatctgg gagatatgat ggctcaggat tttgcagaaa
    16561 aattgagtcg aactaaacct gcctcagtca tcatgatttt agatcattgg gaagacttgc
    16621 aagaagagct ggaagttgtt cagcgttttg cagtttcata catttataag ccagtcctta
    16681 tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg tcgggacttc attgatcaac
    16741 actgcagtct gatgaaagtt ccaaggacct accgcaatct taggatagat gttgaacatc
    16801 acacggttta tcgtggtgaa gagatgattg ctctgacccg ccgtgagtat gaccttttgg
    16861 cgacacttat gggaagcaag aaagtattga ctcgtgagca attgttggaa agtgtttgga
    16921 agtatgaaag tgcgaccgag acaaatatcg tagatgtcta tatccgctat ctacggagca
    16981 agcttgatgt taaaggccaa aaaagctaca ttaaaaccgt gcgtggtgtt ggatatacca
    17041 tgcaagaata gataagcagt tgcagttgtg taactgcttt tttgaggagt ttttatatat
    17101 tgacatgcag tcgggtcttt gctacaatcg ttttaggagg atatatagat gaaacttttg
    17161 aaaaaaatga tgcaagttct actagcagtc tttttctttg gtttgctagc tacaaatacg
    17221 gtatttgcga ataccacagg tggccgattt gttgataagg ataatagaaa atattatgta
    17281 aaagatgatc ataaagcaat ctattggcat aaaatagacg gtaaaactta ctattttggt
    17341 gatattggag agatggttgt cggttggcaa tacttagaaa ttcctggaac aggttatcgt
    17401 gataatttat tcgataacca accagttaat gagattggcc ttcaggagaa gtggtactat
    17461 tttggacaag atggtgcttt gctagaacaa acagataaac aagtactaga ggcaaaaacg
    17521 tctgaaaata caggaaaagt atacggtgaa caatatcctc tatctgctga aaagagaact
    17581 tattattttg ataataatta tgctgtaaag acaggctgga tttatgaaga cggcaattgg
    17641 tattatttaa ataagctagg aaattttggc gatgattctt acaatccact accaattggt
    17701 gaagttgcta agggttggac tcaagatttt catgttacta ttgacattga tagaagcaaa
    17761 cctgctccat ggtactacct agacccagaa actggcatta tgcgaacagg atggcaatat
    17821 ctaggtaata actggtacta cctccgttca tcaggagcaa tggcaacagg ttggaaatat
    17881 gtacgaggca aatggtatta cttagataat aaaaatggtg atatgaagac tggttggtat
    17941 caagatggtt caacttggta ctatttagat ccttctaatg gagatatgaa aataggttgg
    18001 acaaaagtaa atggaaaatg gtattatctc aattcaaatg gagcaatggt tacaggtagt
    18061 caaactatcg atggtaaagt ttataacttc gcttcatctg gtgagtggat ttaatgttgg
    18121 aggatatata aaatgaagct tttgaaaaaa actatgcaag ctggactaac agtaattttc
    18181 tttggtttgc tagctacgaa tacagtattt gcagataact ctgaaggatg gcagtttgtc
    18241 caagaaaacg gtagaaccta ttacaaaaag ggggacctca aagaaaccta ctggcgagtg
    18301 attgatggta agtactatta ttttgattct ctatctggag agatggttgt cggctggcaa
    18361 tatatcccgt ttccatctaa aggtagtaca attggtcctt acccaaatgg tatcagatta
    18421 gaaggttttc caaagtcaga gtggtactac tttgataaaa atggagtgct acaagagttt
    18481 gttggttgga aagaattaga gattaaaact caagacagtg ttggaagaaa gtatggggaa
    18541 aaacgtgaaa attcagaaga taaagaagag aagcgttatt acacgaacta ttactttaat
    18601 caaaatcatt ctttagagac aggttggctt tatgatcagt ctaactggta ttatctagct
    18661 aaaacagaaa ttaatggaga aaactatatt ggtggtgaaa gacgtgcagg ttggataaat
    18721 gatgcttcag cttggtacta cctagatcca gcaactggta ttatgcaaac aggttggcaa
    18781 tatctaggta ataagtggta ctacctccgt tcctcaggag caatggccac tggctggtat
    18841 caggaaggta ccacttggta ttatttagac cacccaaatg gcgatatgaa aacaggttgg
    18901 caaaaccttg ggaacaaatg gtactatctc cgttcatcag gagctatggc aactggttgg
    18961 tatcaagatg gttcaacttg gtactaccta aatgcaggta atggagacat gaagacaggt
    19021 tggttccagg tcaatggcaa ctggtactat gcttatagct caggtgcttt ggcagtgaat
    19081 acgaccgtag atggctattc tgtcaactat aatggcgaat gggttcggta atgaaagaag
    19141 cgattgtgaa tggaaacaat cgcttttttt gtgaaaatat aataaaatag ataggaaaga
    19201 attaatactt gtatgaaaaa taagacgttt tttcgtctag taaaaggaaa aaatgacaaa
    19261 aaaagttggt gtcggtcagg cacatagtaa gataatttta ataggggaac atgcggtcgt
    19321 ttacggttat cctgccattt ccctgcctct tttggaggtg gaggtgacct gtaaggtagt
    19381 tcctgcagag agtccttggc gcctttatga ggaggatacc ttgtccatgg cggtttatgc
    19441 ctcactggag tatttggata tcacagaagc ctgcattcgt tgtgagattg actcggctat
    19501 ccctgagaaa cgggggatgg gttcgtcagc ggctatcagc atagcggcca ttcgtgcggt
    19561 atttgactac tatcaggctg atctgcctca tgatgtacta gaaatcttgg tcaatcgagc
    19621 tgaaatgatt gcccatatga atcctagtgg tttggatgct aagacctgtc tcagtgacca
    19681 acctattcgc tttatcaaga acgtaggatt tacagaactt gagatggatt tatccgccta
    19741 tttggtgatt gccgatacgg gtgtttatgg tcatactcgt gaagctatcc aagtggttca
    19801 aaataagggc aaggatgccc taccgttttt gcatgccttg ggagaattaa cccagcaagc
    19861 agaagttgcg atttcacaaa aagatgctga aggactggga caaatcctca gtcaagcgca
    19921 tttacatcta aaagaaattg gagtcagtag ccctgaggca gactttttgg ttgaaacgac
    19981 tcttagctat ggtgctctgg gtgccaagat gagcggtggt gggctaggag gttgtatcat
    20041 agccttggta accaatttga cacacgcaca agaactagca gaaagattag aagagaaagg
    20101 agctgttcag acatggatag agagcctgta acagtacgtt cctacgcaaa tattgctatt
    20161 atcaaatatt ggggaaagaa aaaagaaaaa gagatggtgc ctgctactag cagtatttct
    20221 ctaactttgg aaaatatgta tacagagacg accttgtcgc ctttaccagc caatgtaaca
    20281 gctgacgaat tttacatcaa tggtcagcta caaaatgagg tcgagcatgc caagatgagt
    20341 aagattattg accgttatcg tccagctggt gagggctttg tccgtatcga tactcaaaac
    20401 aatatgccta cggcagcggg cctgtcctca agttctagtg gtttgtccgc cctggtcaag
    20461 gcttgtaatg cttatttcaa gcttggattg gatagaagtc agttagcgca ggaagccaag
    20521 tttgcctcag gctcttcttc tcggagtttt tatggaccac taggagcctg ggataaggat
    20581 agtggagaaa tttaccctgt agagacagac ttgaaactag ctatgattat gttggtgcta
    20641 gaggacaaga aaaaaccaat ctctagccgt gacgggatga aactttgtgt ggaaacctcg
    20701 acgactttcg acgactgggt tcgtcagtct gagaaggact atcaggatat gctgatttat
    20761 ctcaaggaaa atgattttgc caagattgga gaattaacgg agaaaaatgc cctggctatg
    20821 catgctacga caaagactgc tagtccagcc ttttcttatc tgacggatgc ctcttatgag
    20881 gctatggact ttgttcgcca gcttcgtgag aaaggagagg cctgctactt taccatggat
    20941 gctggtccca atgttaaggt cttctgtcag gagaaagact tggagcattt atcagaaatt
    21001 ttcggtcatc gttatcgctt gattgtgtca aaaacaaagg atttgagtca agatgattgc
    21061 tgttaaaact tgcggaaaac tctattgggc aggtgaatat gctattttag agccagggca
    21121 gttagctttg ataaaggata ttcccatcta tatgagggct gagattgctt tttctgacag
    21181 ctaccgtatc tattcagata tgtttgattt cgcagtggac ttaaggccta atcctgacta
    21241 cagcttgatt caagaaacga ttgctttgat gggagacttc ctcgctgttc gcggtcagaa
    21301 tttaagacct ttttccctaa aaatctgtgg caaaatggaa cgagaaggga aaaagtttgg
    21361 tctaggttct agtggcagcg tcgttgtctt ggttgtcaag gctttactgg ctctgtatga
    21421 tgtttctgtt gatcaggagc tcttgttcaa gctgactagc gctgtcttgc tcaagcgagg
    21481 agacaatggt tccatgggcg accttgcctg tattgtggca gaggatttgg ttctctacca
    21541 gtcatttgat cgccagaagg cggctgcttg gttagaagaa gaaaacttgg cgacagttct
    21601 ggagcgtgat tggggatttt ttatctcaca agtgaaacca actttagaat gtgatttctt
    21661 agtgggatgg accaaggaag tggctgtatc gagtcacatg gtccagcaaa tcaagcaaaa
    21721 tatcaatcaa aattttttaa gttcctcaaa agaaacggtg gtttttttgg tcgaagcctt
    21781 ggagcagggg aaagccgaaa aagttatcga gcaagtagaa gtagccagca agcttttaga
    21841 aggcttgagt acagatattt acacgccttt gcttagacag ttgaaagaag ccagtcaaga
    21901 tttgcaggcc gttgccaaga gtagtggtgc tggtggtggt gactgtggca tcgccctgag
    21961 ttttgatgcg caatcaacca aaaccttaaa aaatcgttgg gccgatctgg ggattgagct
    22021 cttatatcaa gaaaggatag gacatgacga caaatcgtaa ggacgagcat atcctctatg
    22081 cccttgagca gaaaagttcc tataatagct ttgatgaggt ggagctgatt cattcttcct
    22141 tgcctcttta caatctggat gaaatcgatc tttcgacaga gtttgctggt cgaaagtggg
    22201 actttccttt ttatatcaat gccatgactg gtggaagtaa taagggaaga gaaatcaatc
    22261 aaaagctggc tcaggtggcg gaatcctgtg gtattttatt tgtaacgggt tcttatagcg
    22321 cagccctcaa aaatccaacg gatgattctt tttctgtcaa gtctagtcat cccaatctcc
    22381 tccttggaac caatattgga ttggacaaac ctgtcgagtt aggacttcag actgtagaag
    22441 agatgaatcc tgttctattg caagtgcatg tcaatgtcat gcaggaatta ctcatgcccg
    22501 agggagaaag gaagtttaga agctggcaat cgcatctagc agattatagc aagcaaattc
    22561 ccgttcctat tgtcctcaag gaagtgggct ttggaatgga tgccaagaca atcgaaagag
    22621 cctatgaatt cggtgttcgt acagtggacc tatcgggtcg tggtggcacc agctttgcct
    22681 atatcgaaaa ccgtcgtagt ggccagcgtg attacctcaa tcaatggggt cagtctacca
    22741 tgcaggccct tctcaatgcc caagaatgga aagataaggt cgaactcttg gttagtggag
    22801 gggttcggaa tccgctggat atgattaagt gcttggtttt tggtgctaag tctgtgggat
    22861 tgtcacgaac cgttctggaa ttggttgaaa cctacacagt tgaagaagtg attggcattg
    22921 tccaaggctg gaaagcagac ctacgcttga ttatgtgttc ccttaactgt gccaccatag
    22981 tagatctaca aaaagtagac tatcttcttt atggaaaatt aaaagaagca aaggatcaga
    23041 tgaaaaaggc gtaaccagcg ccttttttcc atcctcagac tgaggtgact tttttgaatt
    23101 gtgataaaat agaagggaga ggatgaacct atgagaaaat ttaaaatctt tttatttatc
    23161 gaagcctgtc ttctgacagg agctctgatt ttgatggtat cagagcattt ttcgcgtttt
    23221 ctgctgatac tattcctctt tttgcttttg attcgctact acactggtaa agagggaaat
    23281 aatcttcttt tagtagcggc aaccattctc ttctttttca tcgttatgct caatcctttt
    23341 gtgattctag ctatttttgt tgcggttatc tatagtctct ttcttcttta cccgatgatg
    23401 aaccaggaaa aagagcagac caatttggtt tttgaagagg tcgtgacggt taagaaggag
    23461 aaaaatcgtt ggtttggaaa tcttcatcat ttttcaagct accagacttg ccaattcgat
    23521 gatatcaatc tctttcgctt catgggcaag gacactattc atctggagag ggtcatctta
    23581 accaatcatg acaatgtcat tatcctcaga aagatggtag gaacgaccaa aatcatcgta
    23641 cctgtagatg tggaagtcag tctcagcgtt aactgtctct atggggattt gacttttttc
    23701 aaccagccca agcgagccct ccgcaatgaa cactatcatc aagaaacaaa agactatctc
    23761 aagagtaaca agagtgtcaa gattttcttg accactatga ttggtgatgt ggaggtggtt
    23821 agaggatgaa aaaacaagcc tatgtcatta ttgctctcac ctccttccta tttgtctttt
    23881 ttttctccca cagcttgctg gaaatacttg attttgactg gtctatcttt ttgcacgatg
    23941 tcgaaaaaac agaaaaattt gtctttttat tgttggtttt cagcatgtcc atgacctgtc
    24001 tcttagccct gttttggcga gggatcgaag agctttctct aagaaaaatg caggctaatc
    24061 tcaagcgttt attggcaggg caagaagtag ttcaggttgt agatccagat ttggatgcca
    24121 gtttcaagtc cttatcaggt aaacttaacc ttttgacaga ggctcttcaa aaagctgaaa
    24181 atcatagcct tgctcaggaa gaggaaatca tcgagaagga acggaagcga attgctcggg
    24241 atttgcacga tacagtcagt caggagttgt ttgcggccca catgatttta tcgggtatca
    24301 gtcagcaggc tttgaaattg gatagagaaa agatgcagat ccagttgcag agtgtcacag
    24361 ctattttaga aactgcccag aaggatttgc gggttttgct cttgcatttg cgaccagttg
    24421 aactggagca gaagagcttg atagaaggga ttcagattct cttaaaagag cttgaggaca
    24481 agagtgatct tagggttagt ctcaagcaga atatgacgaa attgcctaag aaaatcgagg
    24541 agcatatctt ccgtatcctg caagagttga ttagcaatac cctccgccat gcccaggcat
    24601 cttgcctaga tgtctacctc tatcagacag atgttgaatt gcaactgaag gtggtggaca
    24661 atgggattgg tttccagtta gggagcttag acgacttgag ttatggactg cgaaatatca
    24721 aggagcgggt tgaagatatg gcagggacgg ttcagttatt aacagctccc aagcaagggc
    24781 tggcagttga tatccgtatt cccctgttag ataaggaatg ataaaggagt aaagatgaaa
    24841 attttactag tagatgacca tgaaatggtc cgattgggct tgaaaagcta ctttgacctc
    24901 caagccgatg tagaagttgt gggtgaggcg tccaacgggt ctcaagggat tgacttggcc
    24961 ttggaactgc gtccggatgt tattgttatg gatattgtca tgcctgagat gaatgggatt
    25021 gatgcgacct tggctatcct caaagaatgg cctgaagcca agattttgat tgtgacctct
    25081 tatttggaca atgaaaaaat catgccagtc ttagatgctg gtgccaaagg ctatatgctc
    25141 aagacttcta gtgcagatga attgcttcat gccgtcagta aggtagctgc tggcgagctg
    25201 gccattgagc aagaggttag caagaaggtt gaataccacc gcaatcatat ggaacttcat
    25261 gaagaattga ctgcgcgtga gcgagatgtt ctccaactca tcgccaaggg ctacgaaaat
    25321 cagcgcatcg cagatgacct ctttatctct ctcaagacgg tcaagaccca cgtgtccaac
    25381 attcttgcca aacttgaagt cagcgatcgt acccaggcgg ctgtctacgc ctttcagcac
    25441 catttggtgg ggcatgagga gttttagatg agtttagcag atttacttta ggagctagaa
    25501 gcagcaaaag actctaaaaa gcaaggccca tggaagccta tatgcgccat caattttctt
    25561 ttctaggtat tgcggtgcct gaaagaaata aactctataa aaatatttac cagaagcgaa
    25621 aaaaacaaag attatcgatt gggattttgc agacacttgc tgggaaaagg agcctagaaa
    25681 ataccaatat gtggctgcta actatttgaa agcaatgcag tcttatctaa aggaaaccga
    25741 tttgcctaag ctagagcagt tagtcgtgac aaaatcctgg tgggacacgg tagatatcct
    25801 agatcgagta gtagggagtt tggtgtatga acaccctgaa ctagaagaaa taatcttaat
    25861 actcttcgaa aatctcttca aaccacgtca gctctatctg caacctcaaa acagtgtttt
    25921 gagcaacctg cagctagctt cctagtttgc tctttgattt tcattgagta taaaatggag
    25981 cctatcagat aatatctggc tgagacgtgt cgctattgac caccagttgt taataaaaga
    26041 gaagaccaat actcaattaa tggaaaagat tctacttcat aacttgaacc aaacagaatt
    26101 ttttatcaat aaagccattg gctggactct gcgagactac tccaaaacga atcccacttg
    26161 ggtaacatgc tttattgaga aaaacaagga aagaatggct gaacttagta tcaaagaagc
    26221 aagtaagtac ctctagcgtg attgaaaagc gcagtcatta attgaaaagt ttacctgttt
    26281 atgtgataat ggagggtatt taaagaaggt ggtagatttc ttgattctat agtagattaa
    26341 gaaatttaga atagtacgct ataattacat taggaggata caataatgaa gaaaactgtt
    26401 tataaaaaat tgggtatttc aattattgcg agtactttat tggctagcca gttatcgaca
    26461 gtatctgctt tgagtgttat ttctagtaca ggtgaagaat atgaggtaag tgagacacta
    26521 gaaaaaggtc cagagtctaa tgattcttca ttatctgaga tttcaccaac gtatggttca
    26581 tactaccaaa agcaatcaga agtattatcg gtaatgatga tttgattaaa attgataata
    26641 ctttacagta tccgtattcg acttcagcta tggttttatc taagtattat ggagtagccg
    26701 atggaatgaa tgtagaaggg aggggaagtg cgaattttat taaagataat gtgttaatta
    26761 cagcggctca caactactac agacatgact atgggaaaga agcggatgat atttatgttc
    26821 ttccggctgt tagtccaagt caagaactat ttggaaagat caaagtaaag gaagttcgtt
    26881 atttgaagga atttagaaat ttaaattcta agaatgcaag ggaatatgac ttggctttat
    26941 taattctaga agagcccatt ggtgcaaaat tagggacttt gggtcttcct actagtcaaa
    27001 aaaatttgac aggaataact gtgactatca caggctatct atcatataat tttaaaattc
    27061 atcaaatgta tacagataaa aaacaagttt taagtgatga tggcatgttc ttggattacc
    27121 aagttgatac tttagagggg tctagtggat ctgcagttta tgatgctagt caccgcgtag
    27181 taggagtgca tactttagga gatggagcta atcaaattaa cagtgcagtt aaattaaatg
    27241 aacgaaattt gccatttatt tattcggttc ttaaaggtta ctctcttgaa ggatggaaga
    27301 aaataaatgg tagttggtac tattatagac aacatgataa acaaacgggt tggcaggaga
    27361 taaatgatac ttggtattat ttagacagtt ccggtaagat gcttacagat tggcaaaaag
    27421 taaatggaaa atggtattat ctcaattcaa atggagcaat ggttacaggt agccaaacta
    27481 tcgatggtaa agtttataac ttcgcttcat ctggtgagtg gatttaatgt tggaggatat
    27541 ataaaatgaa gcttttgaaa aaaatgatgc aagtcgcact agccacattt ttcttcggtt
    27601 tgctagggac cagtacagta tttgcagatg attctgaagg atggcagttt gtccaagaaa
    27661 atggtagaac ctactacaaa aagggggatc taaaagaaac ctactggaga gtgatagatg
    27721 ggaagtacta ttattttgat cctttatccg gagagatggt tgtcggctgg caatatatac
    27781 ctgctccaca caagggggtt acgattggtc cttctccaag aatagagatt tctcttagac
    27841 cagattggtt ttattttggt caagatggtg tattacaaga atttgttggc aagcaagttt
    27901 tagaagcaaa aactgctacg aataccaaca aacatcatgg ggaagaatat gatagcccag
    27961 cagagaaatg agtctattat tttgaagatc agcgtagtta tcatacttta aaaactggtt
    28021 ggatttacga agagggtcat tggtattatt tacagaagga tggtggcttt gattcgcgca
    28081 tcaacagatt ggcggttgga gagctagcac gtggttgggt taaggattcc cctcttacct
    28141 atgatgaaga gaagctaaaa gcagctccat ggtactatct agatccaaca actggcatta
    28201 tgcaaactgg ttggcaattt ctaggtaata gatggtacta cctccattcg tcaggagcta
    28261 tggcaactgg ctggtataag gaaggctcaa cttggtacta tctagatgct gaaaatggtg
    28321 atatgagaac tggctggcaa taccttggta acaagtggta ctatctccgt tcatcaggag
    28381 ctatggcaac tggttggtat caggaaggtt cgacttggta ctatctaaat gcaagtaatg
    28441 gagatatgaa aacaggctgg ttccaagtca atggtaactg gtactatgcc tatgattcag
    28501 gtgctttagc tgttaatacc acagtaggtg gttactactt aaactataat ggtgaatggg
    28561 ttaagtaatg aaggctaatt gtaaactgtg atggatactt aactttgtat aataggtgga
    28621 taaaagtctt cacaatcaaa aaacgcatag tatcaaggtt tttctgtact gccccccaaa
    28681 agttagacaa ataatttatc caaaggattt agttctgtac tgcacaggac taagtccttt
    28741 tagttttacc ttaattctct tgttgttgta ataatcaata tagtctataa tagcttgttc
    28801 caattgatta agtgatttaa atgttttctc atagccataa aacatttccg atttcagaat
    28861 cccaaagaag gactccacca tagtgcttct ctgtgaatgc ctgttccaac cttgtttgta
    28921 cttgttctaa gttgggtgaa gttgaaagat tataggcgat aatttcactg ttaaagccat
    28981 ctaaaactgg tgataagtaa agcttttgag tacttgctgg aatggcaaat tctgtcacat
    29041 ctgtgtagca cttttccatt gttttagagc cttcaaattg gccttgaatg agattctctg
    29101 ccttcttacc aacgtctcct ttattttcgt ttctgtcgca ttttagcttg taaattgagt
    29161 actttcatca agccttgaac tcttttatga tttaccagat aaccacgatt tcttagttct
    29221 aaatgaaccc ggcgataagt ataatttccc ttgtgttcga taaaaatgga ttgaatttca
    29281 gctttaagct cttggtcctt atctggtttg tctagctgtt tcaagtgata gtagtaggtc
    29341 caacgagcta gtttaatggc ttttagaaga agatctaacg aaaactcagt cattaattct
    29401 tgaacaattt ctatctttct tctttctctt tttcctcctt caatcggagt tctcttaact
    29461 tttttaggat agcattctcc gctctcaggt actctctctc ttgttttctc aacaatagta
    29521 tacccgtttt tcctgtattg tgctagccag ttaagaagta tcgtacgact tgggaggcag
    29581 tattcaagag aaactctatc tttagtccag ccttcatgtc agactttatg aatcatttct
    29641 tgttttaaat caggagaata gtaacgattt ttcccttttt tg
//
LOCUS       DAVKZI010000027        28669 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKZI010000027 DAVKZI010000000
VERSION     DAVKZI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.027"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..538
                     /locus_tag="VXB18_001369"
     CDS             <1..538
                     /locus_tag="VXB18_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0382558.1"
                     /translation="SAYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSG
                     TSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDSSSLIKNEVRMMMSCIAYNLYLFLKH
                     LAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNL
                     NLPVPYEPPRRKASLMMH"
     gene            complement(930..1790)
                     /locus_tag="VXB18_001370"
     CDS             complement(930..1790)
                     /locus_tag="VXB18_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0382559.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDITKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1806..3083)
                     /locus_tag="VXB18_001371"
     CDS             complement(1806..3083)
                     /locus_tag="VXB18_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0382560.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(3076..3627)
                     /locus_tag="VXB18_001372"
     CDS             complement(3076..3627)
                     /locus_tag="VXB18_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382561.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3643..4902)
                     /locus_tag="VXB18_001373"
     CDS             complement(3643..4902)
                     /locus_tag="VXB18_001373"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0382562.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(6095..6253)
                     /locus_tag="VXB18_001374"
     CDS             complement(6095..6253)
                     /locus_tag="VXB18_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382563.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(6263..7573)
                     /gene="obgE"
                     /locus_tag="VXB18_001375"
     CDS             complement(6263..7573)
                     /gene="obgE"
                     /locus_tag="VXB18_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0382564.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENIEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7637..7771)
                     /locus_tag="VXB18_001376"
     CDS             complement(7637..7771)
                     /locus_tag="VXB18_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0382565.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7830..8006)
                     /locus_tag="VXB18_001377"
     CDS             complement(7830..8006)
                     /locus_tag="VXB18_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0382566.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(8037..9362)
                     /locus_tag="VXB18_001378"
     CDS             complement(8037..9362)
                     /locus_tag="VXB18_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0382567.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(9378..10421)
                     /gene="cpoA"
                     /locus_tag="VXB18_001379"
     CDS             complement(9378..10421)
                     /gene="cpoA"
                     /locus_tag="VXB18_001379"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0382568.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(10536..10865)
                     /locus_tag="VXB18_001380"
     CDS             complement(10536..10865)
                     /locus_tag="VXB18_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0382569.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10879..11988)
                     /gene="rpoD"
                     /locus_tag="VXB18_001381"
     CDS             complement(10879..11988)
                     /gene="rpoD"
                     /locus_tag="VXB18_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0382570.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11991..13751)
                     /gene="dnaG"
                     /locus_tag="VXB18_001382"
     CDS             complement(11991..13751)
                     /gene="dnaG"
                     /locus_tag="VXB18_001382"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0382571.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLTQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13841..14599)
                     /locus_tag="VXB18_001383"
     CDS             complement(13841..14599)
                     /locus_tag="VXB18_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382572.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMGLTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(14596..15462)
                     /locus_tag="VXB18_001384"
     CDS             complement(14596..15462)
                     /locus_tag="VXB18_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382573.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPIF
                     KQTILKGAKLSK"
     gene            complement(15531..16535)
                     /locus_tag="VXB18_001385"
     CDS             complement(15531..16535)
                     /locus_tag="VXB18_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0382574.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16648..16865)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16948..19644)
                     /gene="ppc"
                     /locus_tag="VXB18_001386"
     CDS             complement(16948..19644)
                     /gene="ppc"
                     /locus_tag="VXB18_001386"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0382575.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDKEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19664..20893)
                     /locus_tag="VXB18_001387"
     CDS             complement(19664..20893)
                     /locus_tag="VXB18_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0382576.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(21049..21351)
                     /locus_tag="VXB18_001388"
                     /pseudo
     CDS             complement(21049..21351)
                     /locus_tag="VXB18_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21456..21745)
                     /locus_tag="VXB18_001389"
                     /pseudo
     CDS             complement(21456..21745)
                     /locus_tag="VXB18_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821711.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            complement(21994..22581)
                     /locus_tag="VXB18_001390"
     CDS             complement(21994..22581)
                     /locus_tag="VXB18_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0382577.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(22660..23087)
                     /locus_tag="VXB18_001391"
                     /pseudo
     CDS             complement(22660..23087)
                     /locus_tag="VXB18_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(23143..23445)
                     /locus_tag="VXB18_001392"
     CDS             complement(23143..23445)
                     /locus_tag="VXB18_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382578.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            complement(23720..25459)
                     /locus_tag="VXB18_001393"
     CDS             complement(23720..25459)
                     /locus_tag="VXB18_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0382579.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKIPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            complement(25622..26506)
                     /locus_tag="VXB18_001394"
     CDS             complement(25622..26506)
                     /locus_tag="VXB18_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0382580.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(26618..27472)
                     /locus_tag="VXB18_001395"
     CDS             complement(26618..27472)
                     /locus_tag="VXB18_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0382581.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(27530..28288)
                     /locus_tag="VXB18_001396"
     CDS             complement(27530..28288)
                     /locus_tag="VXB18_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0382582.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(28350..28538)
                     /locus_tag="VXB18_001397"
     CDS             complement(28350..28538)
                     /locus_tag="VXB18_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0382583.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
BASE COUNT         8579 a         6311 c         4764 g         9015 t
ORIGIN      
        1 ctccgcctac tcagaaactc tctatcaagc aggatcttgg tcgcacaagc gtcgtgtctg
       61 ccagttctct gaacgaaaag aaggaaactt gttctacgat gttatttctc tcgttacaaa
      121 tatgacgagt ggaacaagcc aagaccagtt tcagctttat cgtggacgtg gtcaagccga
      181 gaatttcatc aaggagatga aggagggatt ttttggcgat aaaacggata gttcaagctt
      241 aatcaaaaac gaagttcgta tgatgatgag ctgtatcgcc tacaatctct atctttttct
      301 caaacatcta gctggaggtg acttccaaac tttaacaatc aaacgcttcc gccatctttt
      361 tcttcacgtg gtaggaaaat gtgttcgaac aggacgcaag cagctcctca aattgtctag
      421 tctctatgcc tattccgaat tgttttcagc actttattct aggattagaa aagtcaacct
      481 gaatcttcct gttccttatg aaccacctag aagaaaagcg tcgttaatga tgcattaaag
      541 aacagtcgag atgaaaaaat cgtgtgacgc accaagggag gagtctgccc ttttgaggaa
      601 atctagcgag gaaaaacgat actggaacag cagaaagtaa aactgacctc atgaggagga
      661 agaaagtggc tcatgaggtc aggggttttg taagttacat ctagttgaga gaggtatgaa
      721 tgatttgggt ttactaatag tatataggag gagagccctg aatcctagac cctttgttat
      781 gatgcgctta caaacagagt tggaaaaaat cttaaaagca gaaaaacgca tgatatcagc
      841 tcctaacact tgatacaatg cgttttatta tgaaaagatc tactggattt tttatcaaaa
      901 taaacttcca gtagtctttt cactttttat taataagttc cttcttcacc ttggctagtc
      961 aagataacag gtccatcttt cgtaatgaca aattggtgtt catactgaca tgacaatcca
     1021 ccgtcaatgg tcttatgcgc ccaaccagtt ttcatatctg tatcaatttc ccaatcgcct
     1081 gtattgatca ttggttcaat ggttaagacc attccttcac gaagacggag tccacgacct
     1141 gcaataccat agttaggaac cattggttct tcgtgcatag ttgggccaac accatgacca
     1201 accaaatcac gcactacacc gtaaccacga ctttcagcgt attcttgaat agccgcaccg
     1261 atatcaccga tacgatttcc aacaacagct tgctcaatac ccttgtacat agcttctttg
     1321 gttatatcca tcaagttttt gacttcttcg gacggtgtac caacagcata agcccaacat
     1381 gagtctgcta aaccaccaga atagctctga gtgtattttt tcatttgttc aacattgttg
     1441 aagtttaatt ttgagacatt caggtcggat ttagcaatgg gacctcccaa aaccatatca
     1501 actttgagca aatcaccatc tttcaagata taatgacgag ggaaagcgtg agccacttca
     1561 tcgttaagag agcaacaggt agcataagga tagtccatca tggcaccgtc aaccccaatc
     1621 tgaagtggaa ggaaattttc ttctttacaa cgacggcgga catattcttc aacttcccac
     1681 atatctacgc ctggtttaat caaatcacgt aagcctatat gaatacttgc tagaaaatca
     1741 ccagccttgt ccatagcttc gatttcacga gctgatttta atgttatcat cttttctcct
     1801 agtttctaat taattttaac agtcacattt gcttttgaaa caatctggtg accatgataa
     1861 atatcgtaat caattatagc tgaccgtctc gtatgatgaa taatccgtgc ctgaatgcgc
     1921 aatatatcat ctatctgaac agcctgcaaa aagtagatca gcatctgctc gataatgaga
     1981 ttgcgaccac tattaacaac taaatcttgg gtcatgtggg tcagaatttc tgccaataca
     2041 ccattagcca aaactccatt tttttctagc ataaagggtt ccactgtaat aactacttca
     2101 tcatggtgat aagagagctt ttgtccaatc tgctcagaaa aagttggtag agccgaaact
     2161 tgggaacggc tcatcttctc catgacatct cgtcgcgtca caacgccaag caaagtttga
     2221 ttgcttcgaa caactggtac catttcaaag tcttctgcga tcatccgttg actcacattg
     2281 gcaatatttg tcgataatcc aaccaaaaat agactacgag acataacctt atcaattgtc
     2341 gtgcttggtg atttatcacc agcgtctctc atggttacaa cgccaacaac gacctgatgt
     2401 tgattgataa cagggaaacg gctgctacga ttcttacgaa ccaagtccaa ataatcttta
     2461 actgtatctg tctctctcag aaaaccatac tcatgactag ggcgataaag tttctcaact
     2521 gtcagaatat cagtcttgat ttggacattt gacaaggctt tattgatcat ggtcgcgacg
     2581 gtaaaggtat catgcttact tcttagaaca ggaatccctt tttgattggc cagtttaagc
     2641 acatcatcat gaacctgaaa tccccctgta accagaactg cattttcatt ttccaaggct
     2701 agcaactgaa tacgggttcg gtctccgaca atcaagagcc ccccatcatg aaggtaagac
     2761 aagatatttt gttcagtcat ggcaccaatt gaaaacttac taaattctct ctctaaacct
     2821 tcttgcccag ccagaacctc agaagaagtc acttctgcaa tttcagcaaa cgttaatctc
     2881 tctatagcaa ctttctggga tttaacacga attgttccac ttctaggacg ggtctccaca
     2941 attccacggt tttcagcttc tttaatagcc cgataggctg ttccatcact aactcctaga
     3001 tgattcgaaa tgctacgaac actgaccctt ttacctactg gtaattcctc caaatagctt
     3061 agaatttcct gatgcttact cattgaactc tccttttaca taccgaaatt caagataatc
     3121 ccgcattttt cttgtgtaac gatcacttcc cttaaactga cggaacaaac taaatccaga
     3181 cttaagagca actctttggc tagctttatt ttcaaggtgg gtaatgatag ataattgttt
     3241 taagccaaat tcctcaaaag aaagctgaca aatttttcta acaacctctg tcataaatcc
     3301 ttgcgaccaa gcatcttttc tcaaaaaata gccaagctca gcttcttttt tgatttcatc
     3361 taacttctca aatttaatag aaccaatcat ttgttgattt ttctggtcac aaattgccca
     3421 cactcccaaa ggggacttca taaagtaatt ggccagtgca tattgacttt cttccagact
     3481 tgcctgcgtt gggaaaataa attgaagatt ttctggattt gaagctatct cgcggaagtc
     3541 ctgactatca ctaaaaaaga aaggacgcaa atacaagcga tccgtttcaa aaaaagaaaa
     3601 cattgctaat ttggtccaaa tattcataaa cacctctacg gtttaatcct caacaagtct
     3661 aatatccgct cctaaattac gtaatttttc gataatatca gaataaccac gtaagataaa
     3721 ctcgatattg gtaatttcag ttttaccttc agccataagc ccagcaatga ctagtgcagc
     3781 cccagctctt aagtcggtcg ctttaacact ggccccacgt aaatcacgtc cacccgtgta
     3841 caaaatatga ccatttgttg tcgaaatatc cgcatccatc tttgctagtt caaaaacatg
     3901 atttacacgt ttttcgtaaa tcgtatcgac aattgtacca cgaccattcg ctcttagtaa
     3961 aagaggggta agcggttgtt gcaaatcagt tgcaaagcct gggtaaggag ctgtcttaat
     4021 attgattgct ttcaaattag actgttcctc gacaaaaatg ctgtcttcag atacagtcat
     4081 tctcactccc atttcttcca acttagcaat aaacccttcc aggtgttcgt aaagaacatt
     4141 atttatacga attcctttac caactgcagc agctaaagat atatatgttc cagcttcaat
     4201 gcggtctgga atcacctgat gacgtgtccc atgtaatctt tcaacaccat caataatgat
     4261 gatattagtt cctgccccac ggatatgggc acccatatta ttcaagagag tagctacatc
     4321 aataatctca ggttcacggg ctgcattttc aataatagta cgaccatttg ctttaaccgc
     4381 agcaatcatc gtattaatcg ttgctcccac actaaccgta tccatgtaaa tacttgcacc
     4441 atgaagtcct gtatctttag cagataactt catgttatct ccctcgtagc tagcagtggc
     4501 acccatagct tcaaacgcct taaggtgtaa gtcaatcgga cgaggaccaa gatcacatcc
     4561 tcccggtaga ccaactgtcg cttcaccaaa acggcctaag aggctcccat aaaaatagta
     4621 agatgcacga agactgttaa ttttaccata aggcattgga atattttgaa cacctcttgg
     4681 atcaatctcc aagacatcgt cataacgctt aacagtagct cccatcaatt ccatgatttc
     4741 gacaagactg gctacatccg aaatatctgg aacacaatcc aaagtcacca catcatcagc
     4801 caatataata gctggaatta aggccacaac actattttta gcaccactaa tagtaatttc
     4861 accttgcagt ggtaatccac cattgataac aatttttctc attctaagtt ttcaatactc
     4921 tttcaagatt tctaataagg tcttcaaaat aaagtatatc ataaatttat ccttttttcc
     4981 atccttttca attttattgg ataaatcaga gttgacgagt tagtaactga attactaata
     5041 ctcaataaaa atcaaagatc aaactaggaa actagccgca ggttgctcaa aacactgttt
     5101 tgaggttgta gatggaactg acgtagtcag tatcctacac gtacggcaag gcgatattga
     5161 cgtgatttga agagattttc gaagagtata atctttctcg aatcgctatt gccccttttt
     5221 tatcctctga aaccgagtag gagctaagac tagatctctt atctaagtat cggaatacgg
     5281 ctgttcaact aaattttatc aagaacttct cccccttctc tcagttcaca gaagcgtttt
     5341 atacataccg tccctatatt tcatgaacaa gacgttttca ggctagcatc ctatcagaca
     5401 atctatttta aagataaccg tgactcagga tcgcttctat ctgtcgtttt ctctttatag
     5461 tgatagacct cacgggataa gtcgtacatc tttcctcgtg tatagaagat atgaggacgt
     5521 taaaagatta cagtgaaaat agaaaatctt agtacgaatt caattactct cgtgatttac
     5581 gcatataggt tacgactacc tttttggact ttagtgcttt tggccccctt atccgctata
     5641 tacaccttat tatcacgttc ttgttcgtag agccacgatt tcgctattcc ttcttctgac
     5701 aattcttatt tccagcgtca gacttaaaac ggtctatccc cagaccattt taatccgcta
     5761 cctcacgata gtcaggcttg ggaatcgcta tttgactcgc cgagaacttt gacatcagat
     5821 atactataac aaattgaaat aagaataaaa caatttaatt ttgaaattca aatcaattta
     5881 taacaatata gttgattgaa actagaatag tacatctctg cttctaaaac attgttagaa
     5941 atcgatttta ctgtcctgat cgatttgtcc tgttctcatt tcattttact atattttaga
     6001 agatatgctg tgctattcca gattcagttc gctatacatg cccgtcgtac cacaaaatcc
     6061 cgtgtctgat gaggcacggg attttttagc ttctttactg agatggattt tcctttttag
     6121 ttcgtgccaa tctcaaggca cgatttggat tgagacgatt aaatagttct tccaatttct
     6181 tttcattcca aacgtctgcg gcggaaacaa aattaccatc cgcatctcgg aaagatatcg
     6241 gtttatctcc cataccagtc tcctagtcta caaattcaaa ctcaaattta ccaatgcgga
     6301 ccaaatcccc atctttagct ccacgcgcac gaagggcttc atcaaccccc ataccacgaa
     6361 gctgacgggc aaatttcatg acagattcat cacgatcaaa gttggtcata ttaaagagtt
     6421 tcatgagttt ttcaccagaa agtacccatg tcgcatcgtc atcacgacta atttcaaagg
     6481 ctttttcttc ttcgtcaaat ccatagtaag cttcttcttc catatcggac tcgtcgtaga
     6541 gcaaaaattc tggtgtcttg tctaacaatt cagctgtagc atctaaaagt gttgccagac
     6601 cttgcttggt caatccagaa attgggaaga tagctggtaa ctcttcaaat tcatcataat
     6661 tttcagccaa ttttttctta aagtcttcaa tattttcctg actctcaggc atgtccatct
     6721 tattagctac aataatctgt ggacgctcca tgaggcgaag attgtaagac tccagctctt
     6781 tattgatagc taggtaatcc tcatatggat cacggccttc gctagctgac atatcaatga
     6841 tgtgaaggat aacacgtgta cgctcgatgt gacggaggaa ctgagttccc aaaccaacac
     6901 cttgactagc cccttcaatc aaacctggca agtcggctac tgcaaaggat tcacctgatt
     6961 gggtgcgaac catacctaaa tttggtacaa tagtggtaaa gtggtaggca ccaattttag
     7021 gcttagctga ggtaataaca cttaaaagtg ttgacttccc tacagatggg aatcctacta
     7081 aaccgacatc tgccaagatt tttagttcca attgtaactc acgttcctga cctggttctc
     7141 cattttcaga gatttccggt gcaggatttt ttggtgtcgc gaaacgaata tttccacgtc
     7201 caccacgacc accgtgggca acgataaatt cttgcccatg ttcaatcaaa tctgttaaaa
     7261 ccttgccagt ctccgcatca cgaacagtcg taccttgtgg tactcgaact ctaaggtcct
     7321 cagcaccacg accatgcatc cctttggtca tccctttttc accagaatca gccttgaaat
     7381 gacgattgta gcggaaatcc atcaaggtac gtagtccttc gtctacaacg aagaccacat
     7441 tgcctccacg accaccatca ccaccccaag ggcctccatt agggacatat ttttcacgac
     7501 gaaaggcaac cataccatcg ccaccattac cagccttgac cttaatctta gctgtatcta
     7561 aaaacatact cattatttct tctcacttta aaaaagggct gggaaatccc agtcactaaa
     7621 ttttcttgaa tctattttat agattactga gggcaccaat tgcagttgca aaaattccca
     7681 ataaacttgc tactagcatg ataatcacga taaacaaggt tattttctca aacatagttt
     7741 ttttacgatt tccattatct ccaaatgcca tttttctctc cttcgttaca ttctattttc
     7801 tattatctta gcatgaattg agctagtttt caatagtcag ttgctactgg tgcgataatc
     7861 cataaaataa tgtaagctac aattccagct ccgtaacagc aagtaagaac accccaaatg
     7921 acttgaacga tagtcggatc catatccaga taatgggcca ccccagcaca aacacccgca
     7981 atctttttat cacgaccgct tctcattaat tgtttttttc atagctgttc ctctttctat
     8041 tcttcatggt ctttccaata gtctctcata ctgatcaact gtgtttttga agccttcaac
     8101 atgcgtctag atccttttac aggtacagca accacctgtt gctgaagata caaaactgtc
     8161 ttaaagatac gctgactgac cgtatcatct ttagccaaat ctttctggaa gttatttgaa
     8221 ataatggcat ccagataaaa ctcatgcact cgtttcccaa agttctcagc tgaaatctca
     8281 tacaatttct ctgataaggt atgctcgttc atgtctggtg ttgcaatcag ggcttccaaa
     8341 atagcaccag ccaaatcatg ttctccatag tacaaggttc caaacatttt atcactgatg
     8401 aggttgttca aataaggatt tccgtgagca atgacaggtg ttccactggc taagctttcc
     8461 aagtaggtca aaccttgcgt ttcgcttgtc gatgctgaaa tgaagaaatc cgccgcttta
     8521 tagtaaagag ccgtctcact aggagcaatc atccctgtaa agatgactga gtcttgaatc
     8581 tctaggttct gggcttgctc tttgaggtca ttcagataag ggccatcccc agctactacc
     8641 agtttaacct tgtcttcctc tttcagaaca tcagcaaagg ctgctaaaac tgcttgaata
     8701 tttttttcat aggagattct cgaaagacta agcaacgtct tttcaccatc ttgaatccct
     8761 agtttactac gcagttcttt caaattttcc tgcttgattt ccggacgctc aaacttggct
     8821 aattcaatcc cagtaggaat gacccgtttt tcaaccttga ccttataatc agatagcaag
     8881 tcacggacaa tctcactagg gcaaataacc ccatccacat catgcaggaa acctctaacc
     8941 agatacttga ccatactcgg ccggatcaac atccccttag caatataatg gacatagtct
     9001 tcatactggg tgtgataggt atggatgact ggaattttca attcacgcgc aatccaaatc
     9061 cccaacaggc caagagaaaa ttctgtctga gtatggataa tatctagctg atactgttta
     9121 gcaatttcaa gtgccttgct aaaacctcgg taggcaaagc gacgatcctt aaaagcaaag
     9181 aaaggaacac ttggaatgcg gataatttgc caatcttcgt agcgattgac atccttatct
     9241 gtcgtcgtaa agataaaaac agcatgtccc tgcttttcaa gttctgtttt caaggttcga
     9301 atactggtcg caacaccaga aacctgagga aaataggtat ctgtaaataa accaattcgc
     9361 atagattacc tcacttttta ctttctccct aaagcggctt gtttctcata aaaatccaac
     9421 cagatttgta acagatgctc ttcagaatac tctctggaaa tattcttagc cttttctttg
     9481 agatctttta aggcagcagg atttgcttga tattccaaaa tagcctcttt catctcttct
     9541 ctacccgctg tcgcccgata atttccctcc aaaatcacct tatagagatc taaatcacgc
     9601 aacataatag gagcctcaca actcgcagct tctaaaatag tcataggaaa gagctcattg
     9661 taactaggca acaagaaaag atccgctaga gcatacaatt cgcgcatccg ctctggcgat
     9721 acaatgcctg gaaaaatcaa atttttaggg ggattttcca taattttctt atagtgttca
     9781 taaccatctg tcataccacc aaaagagaag ccaccagccc agataaaggt aatctgaggc
     9841 aattcctcag ccagacggat aaagtcatca atccctttac gtttctgaac ttgcccagca
     9901 cctactacga taaactgatt gtcactaaga ccaagatctg tgcgcagtct gactacctct
     9961 tcttgtggta gaggatgcca tttttccttg ttgacaaagt taggaatata ggtcactttt
    10021 tcacgtggaa taccagctgc taccaaatcc tcaataaaca taggattgac cacaaccaag
    10081 tgctccatcc ggttgtaaaa agaaaataca tagcgtttca caattccctt taagaaaaat
    10141 ggaattttca aacttccctc aagtgtagct ggcaagaaat gcacatagcc aatctttctc
    10201 cctgagcgtt tcttttggaa ggttgataaa taatagggaa aatcaatcgt atgaaagtga
    10261 gtcacatctg cctcgattgg aagattttct gtaacaatca attggtcctt ggcagcacgg
    10321 tgaagaagac gaactaattc acggtaagca cctgaaactc cctgtcctgc tactttctca
    10381 cttgaactca acatattgat gcgtaatttc tttttctcca taactactat tatatcattt
    10441 tctttgaata aaatcagcaa aagaaaggag agactagagg aaaagagggg aaatttcctc
    10501 gcttttccaa cagtctctca catgctttta tatgtttact taatgcctag ggcaatgcgg
    10561 gcatagcgac tcattttttc aactgtccag gctggatacc agactaattt aacctcagta
    10621 tccgttactt ctggaacctc tatcatagca tcataaatct ggtctgtcaa aaggtctgct
    10681 aagggacaac ccatagttgt caaagtcatg tcaatctctg tttgccctgt gtcaccgtca
    10741 aaacgaatct catagatcaa accaagattg acaatatcga ttcccaactc agggtcgatg
    10801 acttcttcca aggctgttaa aatccgtgtt ttgatgtttt caatttgctc ttctgtataa
    10861 gccatatttt cctcactctt agtcttcaat aaaatcacga agcggtttgc tacgacttgg
    10921 ttggcgtagt tttctcaaag cctttgcttc aatctgacgg atacgctcac gagttacgtt
    10981 aaagactttc cccacatctt caagtgtgcg catttttcca tcatctagtc caaaacgtag
    11041 acgcagaaca ttttcttcac ggtctgtaag agtatctaag atttcatcca attgctcacg
    11101 caagacgata cgagtcgtat aatccactgg attttcaatc acttcatctt cgataaagtc
    11161 tccaaggtgg ctatcgtcct cttcaccgat aggagtttcg agagatactg gttcttgggc
    11221 aatcttcaag atttcacgaa ccttatcagg tgtcatatcc attcgttcag caatctgttc
    11281 tggtgtcgga tcttgcccca attcttgaag gagattccgc tgttcacgaa ccaatttatt
    11341 gatagtttca accatgtgaa ctgggatacg gatggtacga gcttggtccg caatagcacg
    11401 agtgatagcc tgacgaatcc accaagttgc ataagttgaa aacttgaacc ctttagaata
    11461 gtcaaacttg tcaaccgcct tcatcaagcc catatttcct tcttgaatca agtcaaggaa
    11521 ctgcatacca cgaccgacat agcgtttggc aatggaaaca accaaacgaa gattggcttc
    11581 cgcaagacgt tgtttggctt cgatatcacc agcttcaaca gccagtgcca actctttctc
    11641 ctcttcattg gtcaagagag gaacgacccc tatttctttc aagtacatac ggacagggtc
    11701 attgacctta gcagaagttg acccaatcaa gtcctcatcg ctgagttctg gttcttcttc
    11761 attgctaaga acacgcgcac ttggatttcc ttcgttatct gtgatagaaa ttcctgcatc
    11821 ctgaatccgt tgcaagagat cttcaatccc atcagcgtcc aaggtaaaag gaataaccaa
    11881 acttgcattg atttcatcat ctgttgctgt ccctttttgc ttatgattac ggataaattc
    11941 tgctacctgt acgtcaaatg ttgttacttc tttttgtttt gttgccatta ttactccatt
    12001 cttctctttt gggaaattaa acgttccaat tcttctaggg ctgtatctgt atctcctaca
    12061 tggctagctt cctgcacctt ctttttgatt ctcatattgt cctgattcaa gagagccttg
    12121 tttcgagtca tctctacttc actaagttcc tgcggcgata tctcagcagg caaatcctga
    12181 gttaaaactt ggtaccaagc tctttcaact tcctctgtct gctctgctaa aacttctgga
    12241 ggaagatttc catactggcc aagcaagtca tataagacct gaaattcagg tgtagcaaat
    12301 gcaaagtctt ctcgcaaacg gtaatcgttc aaaacaagag gggattccat catccgatag
    12361 agtagatggg cttctgccct cataatagcc gataactgct tggtgatagg catggtgatt
    12421 ggcgtcggtc tggaaattcc ttccatgcga ttctgccttt gcacctgacg actctcatta
    12481 acaatctgct caatctgggt ataatcaaag gacgccagac tgtcagctaa aatatgaata
    12541 tagctgtttt gagcagcgat ggacttttct tgaacaatca agggagctat tttttcaata
    12601 aactcaatct gagcctgcag attttcactg ttttcaggtt tgtactgatg aatgtagaac
    12661 tcaatcggac taatacgagt ttttgttaat agataggcca agtcttctgg accatttttt
    12721 tgtagatact catcaggatc caagttatca ggcatgctaa cgatttgcac aggcatatca
    12781 ccaatttcat ccaatgcttt caatatcgcg gcttgcccag ccttatctcc atcgtaaaca
    12841 agaaccaatt tcttggttaa ccttttcaga tgctcaacat gctctcgact caaggccgtt
    12901 cccatcgacg ccacagcatt ttcgattcca gcccgatagg ctgcaataac atccatgaat
    12961 ccttccatca ggtaaatctc actagctttt ccagaagatc tttttgccct atccatatga
    13021 tataattcgt aacttttgtt aaaaattgca gtcgatcggc tgtttttata cttagaagtt
    13081 tgtgaatccg ttttttgcca gatacgacct gagaaggcaa tgacctttcc ttggtcattt
    13141 gtcaggggaa acataatgcg attgtgaaag gtgtctacaa attgattggc atccgagaga
    13201 taaaacaggc ctgaatccag taaatcctct tcacgatact gatcagacaa acgttgatag
    13261 agatagtttc gttctggagg tgctaaacca atccaaaaat gtttaagcac ttcatctgtc
    13321 aaaccccgct gataaaggta atttctggcc tcttctccca tagtcgttgt catgagaata
    13381 gcatggtaaa atttggctgc atcttcgtgc atatcataaa gagcttggtg aggcgaggct
    13441 ggcttctgtt cactataaag cggtttttca acctcaatcc cgacacgctg acctaagatt
    13501 tggacagcct ccataaaggt aaccccttgg tactcctcga tgaatttaaa gacatcacct
    13561 gagcgaccac aaccaaaaca gtggtaaaac tgcttgtcct ctacaacgtt gaaagaaggt
    13621 gttttttcac catgaaaagg acagagccct agatagttcc gtcctgcctt ttgtaaagaa
    13681 atcacatctc ctatgacttc cacaatgttg gcattgtttt tgatttcttc aatgacttgt
    13741 ttgtcaacca tacacaatac ctccatgtta tcatagttta ctttatatag tatactttat
    13801 ttcagaaaaa aagtaaacca tttcactcat tttccctact ttattcaaag agttgataat
    13861 aatcagagat tttcattttt gctttttctt cttggtttaa atcttggata atccgtcctt
    13921 ctttcatgac aatcaagcga ttgccgtatt tgagagcatc ttccatatga tgagtaatca
    13981 taagggctgt tagctgatct ttcttaacaa attcatctgt caatcccatc aaagcaacac
    14041 tagtctttgg atccagggca gcagtatgct cgtctaacaa gagtaattca ggtcgcttca
    14101 aggttgccat caagagactc aaagcctgtc tttgtccacc tgataagaac tcaatcggtg
    14161 tattcaagtg tttctcaaga ccatttccta ctttttcaat ggttgcctga aattcatcct
    14221 tatagctagt caagcgtcgt ggtaacaatc cacgcttttc accacgaaac ttggcgatta
    14281 aaagattttc agcgaccgtc atacggggag ctgtccccat ctttggatct tggaagacac
    14341 gagacaggta cttggcacgc ttctcgggtg aaaacttagt gagttcttca cctaaaatac
    14401 ggatagttcc actagttagt gataaggtcc ctgctatagt gttaaagagg gttgattttc
    14461 cagcaccatt tccgcccaaa atcgtgataa agtcccgttc aaaaatttct aaggaaacat
    14521 catttaaaat aatcttttct tcatcaaagc catttttaac gattttggtt gcatttttta
    14581 attctacaat tgctgtcatt tgcttaactt ggctcctttc aagattgttt gcttaaatat
    14641 tggaatcatg aggcagactg ctaaaatcaa ggcactgtat aaacgaaggt aacttgtatt
    14701 aaagccaagt gcgataactg cccacactaa aaattgataa gcgatagaac ctacaacgat
    14761 agtaaccaaa cgctctgcca agctcaaact cttgaaaata acttctccaa taatcaaact
    14821 tgcaagtccc acaacgataa ccccgatccc tcgagacaca tcggcatagc cttcttgctg
    14881 agcaatgagg gcacctgcaa gggcaatcac accatttgat aagaccaagc ccatgagctc
    14941 catgcgtcca gtatgaatcc cgaaacttct agccatatca ggattatccc ctgtagcaat
    15001 ataggcttgt ccgagtttag tgtccaagaa aaagagcatg agagcaataa caatgctcac
    15061 aaagatgaga cctgtcaaga gttgattcaa atccgaatca aaaggcaaaa catcctgaat
    15121 ttgcttggtt ccaagcaggc ctaaatttgc acgtcccata atcaagagca tgattgagtg
    15181 acaagaagtc atcaccaaaa tccctgagag caaggttggg atcttccctt ttgtataaag
    15241 aaggcctgct gccattccag ccaaacaacc tgctcctaca gcaacaagtg tcgctaaaaa
    15301 tgggttcacg cctttggtta tcaaagtgac agcaacagct cccccaagag ggaaggaacc
    15361 ttctgtcgtc atatctggaa agtttaaaat cctaaatgtc ataaagattc ccagacctag
    15421 aatagcccag acaaatcctt gagaaataat ggaaacaatc atattttatt taatcctttc
    15481 tatattcatc tttttaaaaa atgggaagag tctcctcctc cctaccttat ttattcgatg
    15541 acttgtcctg cttctttgag aacagactca ggaatagtaa tacctagttc ttgtgctatt
    15601 tttttattga tgactgactt accagttgaa aagacattga ctggggtatc ggctggtttt
    15661 gcacctttca agacttgcac aatcatttta cctgttgcca caccaaggtc atgttggtca
    15721 attacaactg atgccaaacc acctacttct accatagctg tcgcactggg ataaattggt
    15781 ttcttagaac tttgattgct agagacaacc gttggaaatc ctgatgcaat ggtgttatca
    15841 attggaaccc aaatagcatc taccttgcta gtcataacag tgacagttga ggcaatttca
    15901 tttgttgaag gaactgcaaa tgtttccact gtcagacctg ctttttcagc ataagcctta
    15961 aattcttcga cctgtgtttt tgaattgtct tcgctacttg agtaaagagc tccgattgtt
    16021 ttcacattcg gtgtcagagc cttgatgagt tcaatttgtt gttgagctgg attgtggtca
    16081 gatacccctg taacgttgcc acctggtttt ttcaaatctt taaccaagtt agcaccaatt
    16141 gggtctgtaa tagcggccat gataactggt aggtcttttg ttgcactagc caacccttgg
    16201 gctgctggtg ttgcgatacc aaccacaagg tcattcccat ttgcaaccaa ttgtttactc
    16261 attgtcgcaa ccttactttg gtcaccttct gagttcataa aatcaatttt aacttgatca
    16321 tctttatatc cttcttctgc aagtccatct tggatccctt tataaatcaa atcaagggat
    16381 ggatggctca caaattgaag cacaccaatc ttagttattt tcttctcatc cttattattc
    16441 tgagcttctg atttattcat tgaagaataa atcaagcttc ctgctactaa gactgctaat
    16501 gcagcaataa ttccaattaa acgtttattt ttcattctgt ttctcctttt tatttccttt
    16561 aacatatttc acttatctaa acaagcgacg ccattgtttt ctttccatac taacctccat
    16621 caaaaaaatc ctcacacaaa aaacttgtgt gaggacgtcg atgcgcggta ccacctcaat
    16681 tatagggaat ttccctatcg ctcagtctcg caataacgag atgcactgta aggtgtgctt
    16741 accgaatttt tataatttca aattctaaat agcattcagc ccaattttca tcattgccac
    16801 ttatctgttt tcagctacca cagactctct aaaaagtttg tatgattact tttctgaatg
    16861 gttaaattat atcattttta aactacttgt caatagtcta ttagaatttt tttgatattc
    16921 acttttagca ttcactcttg aaaattatca acctgaatta cgcaatcctg tcgcaattcc
    16981 gttgatggtg atatgaatca atcgttcttg atcactggac aattctccac gacgttggcg
    17041 tttaatcaac tctaactgaa tatagttgag aatattaaag taaggcatac ggtaatccag
    17101 actagctttt agatatggat tgtcagctaa gagttcgtca tgtccttcaa tagccaagat
    17161 aacgttctta gtaacttgcc attcatttaa aatagtctca tagatggcct taacttgctc
    17221 gtcttcacaa agtttagcat attcaaaagc aatattcata tttgattttg acaaaaccat
    17281 atcaacattt gaaagaagcg attggaagaa aggccaattt tggtacatat ctcgtaagat
    17341 agcaatattc tctggatttt tattgataaa ttccttgaag cttgaaccaa ccccgtacca
    17401 tccagggaac ataacacgac tctgtgacca tgagaatacc caagggatgg cacgcaatcc
    17461 accgatttca gtaatagtct tacgagcggc tggacgagaa ccaatattaa aacttgaaat
    17521 agccttgatt ggacttgact cgaagaaata atcatagaaa tgctcattac caaagaccaa
    17581 atcacggtag atatcgtaac tacggtccac tacttgatcc ataatggctt cataacgatt
    17641 tggggtattg gtatcgctct tcttctgagt aatcatacgg ttaatagctg ccgatactag
    17701 catttcaagg ttatagtaag cggcgtcttt gttaccgtat ttattcccaa ttacttcacc
    17761 ctgctccgtc aagcggatac gatccttgat agacttgagc ggttgagacg taatggcttc
    17821 ataggttggc ccaccaccac gaccgacagt accaccacga ccatggaaga aggtaacctt
    17881 aacgccaaat tcatctccaa tagcagtcaa ttgttgttga gccttgtaga gggtccaaca
    17941 tgatgacaag taaccgccat ctttattact gtcagagtag ccaagcatga tttcttggta
    18001 gttatttcgt gagtcaatcc attttttggc aaggctaaga gaaagatatt ttctcattgt
    18061 ttcctctgaa tgatccaagt cttcaattgt ttcaaaaagg ggaacaatct gaacacgcgc
    18121 cctttccgta tccaccagtc ctacttcttt taacagaata gctaattcta gcatatcaga
    18181 aaggctggtt gcatgtgaaa tgatggtctg acggatgaca tcatctccca acttatcttt
    18241 caaaacacga gccgtcttaa aaatagctaa ttcttttgct aataattctg atttttctgc
    18301 gtgagtcgca gaaagaattc ggggatcttc ttctaattct ttcaagagaa ggtcacactt
    18361 ttcttcttcg ctcaactcgc tataacgaga atgaattcct gctgatttca agagttctgc
    18421 cacacaggct tcatagacgc tagagtcttg tcgcatatca attgatgcta agtaaaaacc
    18481 aaatatctct actgcctgca ataattccac aaaatcacct gaaatcaagg actcgccctt
    18541 attttctagt agagaatctc gaatggcaat caaatccttg tagaaatcat tggcggtttc
    18601 ataacgagtc ccaacttctt tatcctcaat cagataggtt ttagttgcct gaatttttga
    18661 ttgaatatca aacaaggcac gacggtaaag ctctttttcg cggtaaatcg agttatcctt
    18721 ggattgacga gccatttctc tgacttgctt gctgacgttg acaatgctag ttgaaagaga
    18781 aaattcacga taaagttggt aaatcttttt atcatagtag ttcatgatga cttcacactg
    18841 agtgagtgca gactgcttca aggtctttgc tgtaacaaat ggatttccat cacggtcacc
    18901 acctatccac atacccatgg tgattggttt agcctgtttt aaattcagac catgcgcttg
    18961 cgctaagcgc ttatactccg tcgtcaaatg aggtacagct ttcaaaaagg agctgttata
    19021 atattccata gcattcgtga tttcgttagt cacttttaat tttttctcac gaatcatgtc
    19081 tgtctgcatg ataatttcga tgtaacgacg caaatcattg taccatttat ctttattgat
    19141 caaccccaac ttaacatcac ggtatttacg caaaagacta tgaatatgat ttgttaaatc
    19201 caacatactt ttgcgttgca cttgtgttgg atgggctgtc aaaacaggga caacattcaa
    19261 gtgttctagg atctcaacgg cattttcctt ttctgctacc aatttaatcg ttgtagataa
    19321 tttacctaaa tagtcctgat caatattatt ttgatgattg atttcataag ctaaatccac
    19381 atcctctgaa atattaatca aaagaggcaa gatagagaaa tagcgtgaaa tatagaccat
    19441 ttcatcattt gataagctag tcactagacg gtttagacct tgataatctt cctgcgttga
    19501 taattctttc aactgtatta ttttttcaaa ggtctctggg gcaagcatat ttttagtaat
    19561 atcttccagt aattctgtta gaatcaagac ttcttcttgc acaacacttt tattactata
    19621 attttctaat ttttgaagag acataaacta tcctttcttt atcctacttc aacagaaggt
    19681 tcattggttg attttccaat tctcggtaca acttagcgcg tttttcactg gcatcaatat
    19741 ttaagacaaa ggctactgcc actgataaga ctagaagact atttccaccc tgggataaga
    19801 aagggaaagt cactcctgta gatggaatca agcccgaaat ccctccgata ttgacaaata
    19861 cctgaaccaa catcatccct ccgacaccga gtgcaaccat ggcattgaaa ggattctccg
    19921 ctcggatacc gaccaagata atccgcaaaa tcatgaaaaa caagagagct aaaataagac
    19981 tggcaccaac aaagccaaat tcttcaatca cgatagaaaa gacaaagtct gtatgagctt
    20041 ctggcaaata acctcgtttt tcaatcgagt ttccaagacc tagaccaaac caaccaccat
    20101 tgaccatggc aaaataagaa ttagctaact ggtgacctgc atcagcacga tcggcaaaag
    20161 gattaaaaaa ggcactaaag cgcttggcta catagccaaa tactggaatt tttgaaaagg
    20221 tctcaacacc gattaggctg atagtggtca agacaaagac agaagtggca gatacgagcg
    20281 ccagaatggt tgaaaaccag cgataagcga ttccactaac tgtatacata atcaaggaaa
    20341 ccaagactaa aatagtcgca tttcctaaat cagggaaaat tcccaaactt ccaatcagaa
    20401 ctaggagaac gaatcgccaa tcattaaaag cacggggaag ccattgattt tgagtcaaaa
    20461 cttgaaaatc ataagtagct atttcttctt gctgtttgga gaatcggtga gctaaatacc
    20521 aaataataat gatttttaag tactcagctg gctgaatagt tactcctgca accgaaatcc
    20581 aaccgtatgc cccgtttact gaaataccaa taaaacgagc caagaacaat aaaagcattt
    20641 ctattaatat aactaaaatg attagtcgct catttctcaa aaaatctagt ctcaatttat
    20701 aaattaaggc aatcagtatc aaactaacaa tccaaaagat tccttggttt cgaaccaact
    20761 gcaaggcgct cttgccttct tcaattaaaa tagcactggt ggtcgaatag accacaatca
    20821 agcccaaaat agataaaagc aagtagggaa tcaagatgga ataatttaat aagtgcctct
    20881 tactaatctt catagtatca ccactctact aggatacaga caaatctgtt ccaaattccg
    20941 ttttattttc tagttttgat tgctattata ccattttttc agaaagaaaa aaactcttac
    21001 cttacaatcc ttcgaatttt actgttttta cagaattaag gcagaatttg aaatcgtaaa
    21061 accattttga ataagagttg cttcaaccca ttgactccga cgaattaagt tgctttcgtg
    21121 aatgccaaaa tcagccgcaa tttgttcata agtgctctat tctcgcatgt attgaatagt
    21181 taccataagg agatcgtcta ggcttaattt gctttttcgt ccaccttttg cgcgtttacg
    21241 ttgataagct gtttttaaca cagctaacat ctcttcaaaa gtcgtgcgct gaacacctac
    21301 aaggatcttg aaacggctat cgcttaattg tttacttgct tcatcatcca tagttttatt
    21361 gtattgtatt tttgtttcgc aggaagtcta ttattccttt cgttccaagg tttttacgct
    21421 tttagcaaca agcttacaca ctgagcgttt cggacttacc atatcatttc gttggagatt
    21481 ttatcatcaa tttttagatt aaaaaaaatt tcccaatctt cacaaacttc tgtagcagga
    21541 attgtatgaa tctttctaag tatctttgta tctttcctgc ttctacacca tatgtgtatt
    21601 gttggttttc tgaataagct aaaatgctat ctattgcatc tcttccgtct atccattcgt
    21661 gtaaagaatg tacttcgtca tcgcagagtt caatgctaat tggtttacac atcggaactc
    21721 caagagaagc tactttctcc atcatatcaa attcaaattt ttttataatc taacttcgac
    21781 ttatcagaaa cacgcaagaa atatttttac tgattttgat ctgtcacaca atatttttta
    21841 tcatctgacc agcctttatt tatggctatc ttactactaa aatccatcaa gcacactccg
    21901 attcacttta caacactttt tgcagttttc actagtaacc tatccagttc gtctacactt
    21961 ttatttccta gatccatttt tacattatga aagttagtca attttctcta tgatgtttcc
    22021 aagtttatcc aatacaagac aagaatgatc atttagtgga attatgggaa cattaacgag
    22081 ttcttcagct ctatccttat ttgctttatc attccaggaa tcataatgga cactaattaa
    22141 aaactgacta aagagtccta atccattttt tatctttatc tgatgatctg aattatcatt
    22201 aggtgagaca tagacttttt ctcctaatag tagggctcct gcagaaaatc ctataatttt
    22261 tgcctcttta ttaagcatat gatcgatata acttttgaac tcctgattaa cataagtagc
    22321 aatatatttt tccgtatttc caccaccgat gataattatg tcagcatcta gatagctatc
    22381 aagatcaatc tgctcagtgt ccaggagcaa gtaatcaatg tttagattag gaaattgact
    22441 ttgaaaaact tccgtgtact ttttcatgta cggttcccaa ttttctcgaa aaactgtaaa
    22501 aatgataatt cttttaatct tggttgataa tacaatttta tcaacaatac tatatttctt
    22561 cattggggga ttcccaccca tcaaaaaaat ttgttctttc aagttaacac actttctaaa
    22621 gatacataaa gtttaaacaa gtttattcac gtttctaaat tataattttt tcttaaaatg
    22681 aataattcta tttgcctcct gaaatccaat attgagatga aatcttatag aatccgtatt
    22741 cgttaaagta cagtcacttg caaattcctt acatccttta tttttcgcac attcctcaca
    22801 ttttgtacag agatttttag caatatcctt taaacgatat tcctcgtcaa caataatccc
    22861 ttctaagaat ccaacaggac tatatttaca accttcaaca taatcaaatc tgagtgaaca
    22921 tagtgctaga cctacaattg tgtcaccttc aacttcagta aagattgcag tatttttgcc
    22981 attcgtatat tttttacttc atcaatagct tctttatcgg tcaattgggg ccataattgt
    23041 ttcattagtt tagccgtttt tataaaatct tttgttattc catccatatt gatgttcctc
    23101 cgcaaattac aagtaaatgt ttcgaatcat gctgatactt tgttactcat tgattgatac
    23161 caattttata ctgctttcaa aaggctcata tgttttatac ttaattactt cgtctttaaa
    23221 attaaataaa ggtgtatccg gcttagcatt ccataaaata atcaaccaca ttatagcatt
    23281 ataaagctgc tttgcagttt cattccactt ttcaggttgt aaatttccac tccctgtatt
    23341 gtcatattct tgtctattat ttacatgaga atcacctaca agcggattaa aaagaggtag
    23401 ccctttgtga ttaattagtt ctaaaaaatc ccttgccgca cccatgcaac actgaataac
    23461 ttccttcttg tcatcaattt tactctcagc gataaataca taatattcat cttcaatagt
    23521 tgctcctgca tcactatgtt tttgttgatt tgctaacagc ttaatatgtg ctttaggcta
    23581 aacttcaaaa tctctaacaa ttctttgtct tgtttcatgt cctctacaat tcatttaagt
    23641 tctcctttac aagtttagta actagcctta ttatactata taagatatga aatgtaccat
    23701 aatcttcatc aactagtttt tagaaaatca caaatccatc tggagagatg acaagctgat
    23761 tctccaattc ttggcaattg cttgctagtg ctactgcttc tttctctaaa agataatctt
    23821 ctgttgattg gttgaatatt gctttgagga tccgtccttc gtatttccat tccagagcta
    23881 ctagatcaga tttgatttct tgaaggctat acttgccatg cgaaatgatt actgacgcgt
    23941 atttccgaat cttaatcagc ctcttcataa agttcagcat atcattgtca cttgatacac
    24001 gttcccaagg catacaacga cgacaatctg gatctggtcc tccagtcaag gctaactcgg
    24061 ttccgtaata aatgcacggt gttccttttt gtaaaaagag aaaggctaag gctgatttaa
    24121 ccagttgaac atcttcattg gccgtccaca ggattcgctc tgtatcatgt gaatccaaga
    24181 gattaaacat gacctctgaa atctgctgct tgtaatacat agactctcca ttgatttcat
    24241 cgatgaactg gtctgtcttc ttaattcctc gtaagaaata gtccttgata ctatcagata
    24301 aaggataatt catgacggca tggaactcat ctccatttag ccaaggctga gatgtatgcc
    24361 agacttctcc taggatataa agatcaggat ttttagctaa aactgcctta cgaaaatcct
    24421 tccagaactg atggtcaatc tcattagcca catccaaacg ccaagcatcg atattaaact
    24481 cttcaatcca ataagtcgca acctttaaaa gataattctt gacctctgga ttggctgtat
    24541 ttagcttagg catatagtcc tcgaaaccaa aaacatgata gggtaagtct ctcttattaa
    24601 ctagcttttc agttgtcact gggaattgtt gaatatggaa ccaatcctta taagcagact
    24661 gttcaccatt tttgacgaca tttttccatt gaagagattg cgaaccaata tgattaaata
    24721 ccgcatccag catgactttc atgccacgat gatgcgcttg atccaccagt tcccgaaagg
    24781 tctccttgtc tccaaaatga cggtcaattt caaagtaatc tgtcgtattg tacttgtgat
    24841 tgcttgtaga ttcaaagatg ggacaaagat atagtccagt aatacccaag tcttgcaagt
    24901 aatccatatg atcaataatc ccctgtaaat caccaccaaa gaaatcatcg ctcttaggtg
    24961 tgacagatga atcccagtct aaagtccctt ctgggtttaa tagagcattg ccattggcaa
    25021 atctttcagg aaatatctga taccataccg tatttgaaac ccagtcagga atcttgcagg
    25081 catcaatctc atgaagataa ggcaacttaa atccattccc aattgcatga agattttcta
    25141 gagaattttc cacacaccct ttatcgccat acaaaatatt ttgaccttct gtatctctga
    25201 gctcaaagag atactggata cgtgcaaagt caactgacac ttcaacctgc caatggtcaa
    25261 ataaggtacc agaagttatc ttgaccattt cttttgtatc ctgataaaac tcctccataa
    25321 agataaaagg gtccccatag tgcaagttga tgctttcaat gtcccctttc ttagttcgaa
    25381 ttcgaatatg gagtttctta tccttataaa gataggcata ctccgactca ggcctatggt
    25441 aaatagcact caattccatc aatttgtctc ctaaagtatt cattcaaatt ttacgcaaac
    25501 gttttcaaac tcaataaatc cagtatacta tttttgtgaa ctatttgcaa ggaatgtccg
    25561 ttgttaaagg aactatcttt taaagtatac aaaaagcctt aaaaaaggct ttctctatat
    25621 actaatcctc tttcggtttt gaaaatactt ctactcgctg agctaggact ttgatttcta
    25681 caggtaggtt atctgattta tctccgtcaa catctgactc caattcacta tctgaagaga
    25741 ttttaatatt acgcgctttg atatactcga tattatcatt tgcgacaaca tcccctttta
    25801 ataaatcagg aatgacggat aatttggaga atatagaggc atctttcaga atcaaaatgt
    25861 tggcatagcc gtccttgttt tcttcaaaga ttttcttatc agcgaagtaa tttgtcaaaa
    25921 ggaccaaaac atggctagct tcaccaacat aatttccatt ttctgtctca accttaatgt
    25981 taaagacctg atctgtcatg acagacttca tggtatttac agcataggtt aaaataccga
    26041 attttgtttt gtcctctatt tcaacattgt gaatcgcctc aggcagagaa ccgatactaa
    26101 agatataacc aaaatagttg tcatttgctt taccgatatc aatcttattg gttaaatcaa
    26161 aatccagttc gtcaattgcg ccatcgatgt cttgattgat ttccaaaagt tttgtaatga
    26221 ggttacccgt accgcctggg ataatcccta acttaggaat gtagtctctc tcatcaatac
    26281 ctgaaatgac ttcattgaca gttccatctc caccaaacac aaccactgca tcatactgct
    26341 cacgagaagc ttcttcagca aaatgtgttg catccagcgc tttttcggta attttggttt
    26401 caacatattc aaagtattct tttgctttat tctccagctt ttctttgtaa tccaaagcct
    26461 tctcgccacc agaagtaggg ttgataatta ccattgcttt tttcattgat tttatcctta
    26521 attttaaaca gaaatgttta catttcgtcg tatgcaagta aatgtaatcc tattatacaa
    26581 tgaaaataca gaaaagagaa atctgacgta ctggagatta atacgctttt attctatttt
    26641 cccatcgcct aactacatcc tttaagggtt catccaagta agaataggcc ttatccttga
    26701 tccaatcagg aataccgtaa gctgcctctg ctatgctaca agtgattgct gcgagagtat
    26761 cactgtcgcc accaagtgag atggcatttc ttatcgcatc ttcgaagtct ctactttcaa
    26821 gaaaggcgat aatggcttga gggacagttt cctgacatgt ttcgttaaaa cgatagttag
    26881 gacggatttc atctaaagtt tgagatagat tgtaatcgta ttctttttct atataatcct
    26941 taattcgtct tttacactct gtaggattgt cgttaattga ttgctcgtac tctctacaat
    27001 aaccaccaaa gtaaaaacga catagaaaga tagcatcagc tgtagccata gcgcctttga
    27061 caccttctgg atgattatga gttacctctg cagaaagact cgtaagtcct ctagatgatg
    27121 gccacatacc agttttcgca taaaaaccac agtccatgat ccaagcacat ggagaaatac
    27181 gcatagctga tccattccca aagctattat aaggctcacg gttatcgctg tttagccatg
    27241 cattaaaccg agcaccgtaa tcagcattcg gatacattct gccatatttc ttcatcgcgt
    27301 caatgaaatc gtctttttgt ccaccattca taattgcttc tgcaacagca caggtcataa
    27361 ccgtgtcatc tgtaaaaaag cagtccttcc gaaataaagg aaagtccttt gttttgatat
    27421 tgttccattc gtaaacagaa ccgacaatat ctccaataat tgctccaagc atcagattcc
    27481 tccttgttca ttttgatgct ttttatattg gttatatacc atatttattt tagaaaacaa
    27541 catcctgttg gattttaaaa atttcatttt tttcaaaata gggttttacc atttctttcc
    27601 acctagctct atgaaaattg attgatttta aaggagatag gccataattt cccaatgcat
    27661 aaccatcatt tacttcaaca acaagtgttc tgccatcgcg agtaacaccg atatctagtc
    27721 cataagctat tggcgcatct ttccaacatg atatcgcttc atcaattaca cttgcatcaa
    27781 attgtgcatg ataatcacct gtatagggtc gaacatctaa tacgcgacca tctaacacaa
    27841 aacaacgcca ttcagctatg aattctacaa cctcactaat ccatatagga tagtcgaaag
    27901 gtagaccaat acctattaaa tcatgggttc cattaacaac tcttccagta aagacttttg
    27961 aaccagcttt aggcttaata aattttcccc aattatcagg tatattcaca atctctccta
    28021 aaataccagc ataaatcttt cgaccataaa actctttaag ctcaatagga tagtcatgaa
    28081 ccggaacgtt taagcccatc atttttagta atgctctagt ctccattata taatctacaa
    28141 ctatatcttc acttgttaac tcttttattt cagaaaaaga ttgatataaa acagcttctt
    28201 ctccttgtaa gtaggcacct acttgagcat tgtatttatt aattgaaacc tcacttggta
    28261 atttactttg tctaatataa acaaccattt catcactcct atatcactag tgttacacca
    28321 atttgtaaaa aataatagca attttgctct tatttttttg agtaaatagc ccccataata
    28381 tcatcgaaat aatcaacggt atttaggagt aattcaataa cctgggactt tgttagtcgc
    28441 attccccttc tatctctagc atcttctact aaattttcaa gtttctctag atttttatca
    28501 tccaagctaa tcattattct atttttatcg gttgccattt tcatcacctc aagttaattc
    28561 tatcacaggt gtaacacttg tgtcaactgg cttttataat acattagttt aaaagtggag
    28621 aggattttta acacagtaac tttaaatctt tggtattaaa aaattttca
//
LOCUS       DAVKZI010000028        26481 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKZI010000028 DAVKZI010000000
VERSION     DAVKZI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.029"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(136..903)
                     /locus_tag="VXB18_001398"
     CDS             complement(136..903)
                     /locus_tag="VXB18_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0382584.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGSRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(900..1766)
                     /locus_tag="VXB18_001399"
     CDS             complement(900..1766)
                     /locus_tag="VXB18_001399"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0382585.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(1803..3170)
                     /gene="accC"
                     /locus_tag="VXB18_001400"
     CDS             complement(1803..3170)
                     /gene="accC"
                     /locus_tag="VXB18_001400"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0382586.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(3182..3604)
                     /gene="fabZ"
                     /locus_tag="VXB18_001401"
     CDS             complement(3182..3604)
                     /gene="fabZ"
                     /locus_tag="VXB18_001401"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0382587.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKCRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(3601..4086)
                     /locus_tag="VXB18_001402"
     CDS             complement(3601..4086)
                     /locus_tag="VXB18_001402"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0382588.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4089..5324)
                     /gene="fabF"
                     /locus_tag="VXB18_001403"
     CDS             complement(4089..5324)
                     /gene="fabF"
                     /locus_tag="VXB18_001403"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0382589.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(5346..6077)
                     /gene="fabG"
                     /locus_tag="VXB18_001404"
     CDS             complement(5346..6077)
                     /gene="fabG"
                     /locus_tag="VXB18_001404"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0382590.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(6111..7031)
                     /gene="fabD"
                     /locus_tag="VXB18_001405"
     CDS             complement(6111..7031)
                     /gene="fabD"
                     /locus_tag="VXB18_001405"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0382591.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7024..7998)
                     /gene="fabK"
                     /locus_tag="VXB18_001406"
     CDS             complement(7024..7998)
                     /gene="fabK"
                     /locus_tag="VXB18_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0382592.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(8117..8341)
                     /locus_tag="VXB18_001407"
     CDS             complement(8117..8341)
                     /locus_tag="VXB18_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0382593.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(8401..9375)
                     /locus_tag="VXB18_001408"
     CDS             complement(8401..9375)
                     /locus_tag="VXB18_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0382594.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(9375..9809)
                     /locus_tag="VXB18_001409"
     CDS             complement(9375..9809)
                     /locus_tag="VXB18_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0382595.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(9903..10688)
                     /locus_tag="VXB18_001410"
     CDS             complement(9903..10688)
                     /locus_tag="VXB18_001410"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0382596.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11013..12377
                     /locus_tag="VXB18_001411"
     CDS             11013..12377
                     /locus_tag="VXB18_001411"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0382597.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12380..12751
                     /locus_tag="VXB18_001412"
     CDS             12380..12751
                     /locus_tag="VXB18_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0382598.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            12965..14239
                     /gene="serS"
                     /locus_tag="VXB18_001413"
     CDS             12965..14239
                     /gene="serS"
                     /locus_tag="VXB18_001413"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0382599.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(14264..15163)
                     /locus_tag="VXB18_001414"
     CDS             complement(14264..15163)
                     /locus_tag="VXB18_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0382600.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(15273..15821)
                     /locus_tag="VXB18_001415"
     CDS             complement(15273..15821)
                     /locus_tag="VXB18_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0382601.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16039..17361)
                     /locus_tag="VXB18_001416"
     CDS             complement(16039..17361)
                     /locus_tag="VXB18_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0382602.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(17452..17540)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(17704..20040)
                     /locus_tag="VXB18_001417"
     CDS             complement(17704..20040)
                     /locus_tag="VXB18_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0382603.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKEIELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(20144..20692)
                     /locus_tag="VXB18_001418"
     CDS             complement(20144..20692)
                     /locus_tag="VXB18_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0382604.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(20689..20991)
                     /gene="zapA"
                     /locus_tag="VXB18_001419"
     CDS             complement(20689..20991)
                     /gene="zapA"
                     /locus_tag="VXB18_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0382605.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21078..21962
                     /locus_tag="VXB18_001420"
     CDS             21078..21962
                     /locus_tag="VXB18_001420"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0382606.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            21974..22588
                     /gene="lepB"
                     /locus_tag="VXB18_001421"
     CDS             21974..22588
                     /gene="lepB"
                     /locus_tag="VXB18_001421"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0382607.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            22716..25082
                     /locus_tag="VXB18_001422"
     CDS             22716..25082
                     /locus_tag="VXB18_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0382608.1"
                     /translation="MEVYFSGTIERIIFENPSNFYHILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(25130..26413)
                     /locus_tag="VXB18_001423"
     CDS             complement(25130..26413)
                     /locus_tag="VXB18_001423"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0382609.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT         7614 a         6147 c         5161 g         7559 t
ORIGIN      
        1 atttttgtaa gcttacatct acagtataca tcttttttgt ctattttata gtctatctcc
       61 tcaactgtca atttttcaac ctgaattgca tttttccata aaaaatgaga cctttctagt
      121 ctcatttagt cattcttagt attttctaaa tcgttgatag cgttcttcca gcaactcttc
      181 tagcggtttt tgtgaaagtc tagccagctc cgtttggagt tcttttttga cactcttaat
      241 cagttcttta ctagaaagtc ctacttcaga aatcacctta tccaccacgt ccatttctag
      301 cagctcatgc gaagtgattt tcatcaattc tgccgcttcc atggcacgac tgccatcctt
      361 ccatagaatg gaagcaaagc cttctggact tagaatggca taaatagaat tttccagcat
      421 ccagacacgg tccgcgactg ctagagccag agccccacct gaaccacctt caccgataat
      481 gatagcaata atcggaactt tcaggtcact catttccatg agattgcgag cgatagcttc
      541 cccttgacca cgttcttccg ctccgacacc aggataagca cctgctgtat tgataaaggt
      601 cacaactgga cggccaaatt tctcagcatg tttcatcaac cgcagtgcct ttcggtagcc
      661 ttctggatgt ggttggccaa aattccgttt gaggttgtct tgcaaactct tgcctttttg
      721 gataccaacc actgttacag cttgatctcc aagccaacca ataccaccaa caactgcacc
      781 atcatcacga aaagaacggt caccatgtaa ttggataaat tcatcaaaaa tgcctgtcgc
      841 aaagtccaag gttgtcaagc gactctgctc acgcgcttct ctgactattt ttgcaatatt
      901 catctaggac tccctccatg caatctgact aggctagcaa tcgtatctgg taagtctctt
      961 cttttgacaa tagcatccac aaagccatgt tctaatagga attctgcctt ttggaaatcc
     1021 tcaggcaagc tttcacgaac cgtattttca atcacacgac gcccagcaaa accaaccaag
     1081 ctctgtggtt cagccagaat gatatcgcct tccatagcga aagaagctgt cacaccacca
     1141 gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag catttgaatg acgtttaacc
     1201 gccgcagaga tcttagccat ctgcatgaga ctcatgattc cttcctgcat acgggctcca
     1261 ccagaggctg tgaataggac aactggcaat ttttcgacag tcgcatactc aaacaaacga
     1321 gtgatttttt cacctacaac cgtacccata gaagccatga taaagttaga atccataatc
     1381 ccgagagcca cagtctgacc tttaataaga gcagttcctg tcacaacggc ttcatgcaga
     1441 cctgtttttt cacgcataga tgccagtttc ttttggtaac cagggaaatg caagggatcc
     1501 ttgctttcaa tccctgtaaa caattctttg aaggttccca tatcaatcgt caaagccaag
     1561 cgttcttggg cagaaatacg aaaggtatag ctacagtgcg gacagatacg ttcacttccc
     1621 agatccttct gatagatggt atgcttacag cctggacact gggaaaataa ttcatctgga
     1681 acctctggct tagcttgagg tttttcccta accgaacgat tgggattgat tcgaatatac
     1741 ttatcttttt tactaaatag agccattgat tccccttttc ggtttaaact cttaaagtca
     1801 ttttattctt tttcttgata tttaggtaag aaggtttcca tcaagaagga agtatcataa
     1861 tccccagcaa tgacattgcg atctgaaatg aggtcaagct ggaaatctgc attggtctgc
     1921 actccttcaa tctctaattc atagagggca cgttgcattt tcatcaaggc gtcaaaacga
     1981 ttttcgccgt gtactatgat tttggcaatc atactatcat aataaggcgg aatggtataa
     2041 cctggataaa ctgctgaatc cacgcgcaag ccaactccac cacttggcag atagagatta
     2101 gtaatcttac ctggacttgg agcaaagtta aaggctgggt tttctgcatt gatacgacac
     2161 tcgatggcat gaccgcgtag gacaatatct tcttgcttaa cagacaaagg ctgacctgcc
     2221 gcaatgcaaa tctgttcctt aacgatatca acacctgaaa caaactctgt tactggatgt
     2281 tctacctgaa cacgagtatt catctccatg aaatagaaat tgctacttgc ttcatcaaga
     2341 agaaattcaa tggttcctgc attctcatag ccaacaaact ctgccgctcg aacagcagca
     2401 gcacctattt catgacgcag cgtttttccg attgcaatcg agggactttc ttccaaaacc
     2461 ttttggttat tcctttgaag agaacaatcc cgctcaccca agtgaatcac atgtccatgc
     2521 tcatcaccta ggatttgaac ctcaatgtgc cgagctggat agataacccg ttctatgtac
     2581 atggcaccat tgccataatt ggccttggcc tcactagagg cagtttcaaa ggcagaaacg
     2641 aggtcatctg gtttttcaac cttacgaatc cctttaccac ctccacctgc tgaagccttg
     2701 agcataacag gatagccaat tttttcagca acaatcaaag cttcttcaga gttatgcact
     2761 tctccatctg aacctggtat aacaggcaca cctgctttaa tcatctgagc acgcgcattg
     2821 atcttatccc ccatcatatc cataacatga ccagatggac cgataaactt gatacctact
     2881 tcttcacaca tggtcgcaaa tttggaattt tcactgagaa atccaaaacc agggtgaata
     2941 gcttctgcct cagtcaagac tgcagctgat agaactgcat taatattgag ataagactct
     3001 gttgccttgc caggaccaat acaaactgct tcatctgcca aaagcgtatg aagagcttcc
     3061 ttatcagcag ttgaataaac cgctaccgtc gcaatcccca attcacgtgc cgcacggata
     3121 atacgaaccg caatttcacc acgattggca attaaaattt ttcgaaacat ggagaacctc
     3181 cttagttccc aattgcaaaa gtaaggatac cactggctgc aagcttgcca tccacttcag
     3241 cctttgcttc aaccacagct atggtgccac gacattttac aaaagtcgct gtcataacca
     3301 attggtcgcc tggtacaact tgcttcttga acttaacctt gtccatacca gcgtaaaaga
     3361 ccagttttcc tttattttca ggttttgata actccaacac accagcagtt tgcgccaagg
     3421 cttccataat cagaacacct ggcataactg ggtattgagg aaagtggccg ttaaagaaag
     3481 gttcgttaat ggtcacattt ttgatagcaa caatggtatc ctcgctcact tccaagacac
     3541 ggtccactag aagcatagga taacggtggg gaagagcttc tttgatttct tgaatatcga
     3601 tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt tcttcgttag agacgagaat
     3661 ttccgttacc acaccatcct taggagctgg gatttcattc atgactttca tggcttcgat
     3721 aattaccaat gtttgacctt ttttgacact atcaccaact gtaacgaagg caggtttatc
     3781 tggtccagca gccaagtaaa ccactccaac aagtggactc tctacaagat ttccctcagt
     3841 agccacactt gcttcagctg gagctggaac ttcttctgct acagtctctg ctggagcaga
     3901 tgtaggagct actggactcg gtgttgctag aacgggtgct ggagcgactt gagttgcaac
     3961 ttcaggcaca ggtctcgctt cattcttgct aaactgcaac tcatccgtcc catttttata
     4021 agaaaattct ctcaaacttg actggtcaaa ttgagtcatc aagtctttaa tatcgtttaa
     4081 attcatactt atctattctc ccaacgtttg aaagcaagaa ctgcattgtg gcctccaaaa
     4141 ccaaaagtat ttgaaatagc gtatggaatt tctttctcca agccttgtcc ataaacgaca
     4201 ttagcttcga tataatctga tacttcactt gtcccagctg tcattggtac aaagttatgg
     4261 cgcatagctt cgatggtgac gatagcttct actgcacccg cagcccccag caaatgtcct
     4321 gtaaaagact tggttgatga tacaggtact tccttaccaa gaacagctac gatagctcca
     4381 ctttctcctt tttcattggc aggagttgac gttccgtgag cattgacata ggctacttgc
     4441 tctggagaaa tctcagcttc ttccaaggct agtttgatgg ccttgatagc tccctgacct
     4501 tctggatgtg gagaagtcat gtggtaggca tcacaagtat ttccgtaacc aaccacttca
     4561 gccaggatag tagctccacg tttttcagcg tgttcaagac tttctaaaac caacatccct
     4621 gaaccttcac ccataacaaa cccattgcga tccttatcaa atgggatcga agcacgagtt
     4681 ggatcctctg tagtagagag agctgttaag gcttggaaac cagcgatggc aaaaggtgtg
     4741 atagaagctt ctgttcctcc caccaacatc acatcttgga aaccaaactt aatggagcgg
     4801 aaggcatccc caatcgcatc atttgatgaa gagcaggcag tattgataga tttacaaaca
     4861 ccgtttgcac caaaacgcat ggctacattc ccagaagcca tatttggtaa agcttttgga
     4921 agagtcattg gtttgacacg tttgggtcct ttttcatgaa ggcgaagtac ctgatcttca
     4981 atttccttga ttccaccaat accagatgca acgataacac caaaacgatc cctattaaga
     5041 gcctctacat caagattggc atgatttaca gcctcttggg ctgcatacaa ggcatataaa
     5101 gaatagttat caaaacggtt ggtatctttt tttacaaagt atttatcgaa cggaaaatct
     5161 tggatttctg ccgcattatg cacatcaaag tcactatgat caaattttgt aatgccacca
     5221 atgccgattt tcccagttgc taaactattc caaaattctt ctggtgtatt tccgattgga
     5281 gatgttactc cataacctgt taccactact cgatttagtt tcattctttt cacctctagc
     5341 tttcgctaca tacttaagcc accatcaatg gcaatcactt gaccagttag ataatcttgg
     5401 cctgctaaaa atactgtcaa atctgcaacc tgctctgcct gcccaaattc tttcatcgga
     5461 atctgagcta gtgtagcttc cttaatctta tctgataaga tagctgtcat atcagactca
     5521 atcattcctg gagcaatcac attgactcgt atattccgac tagcgacctc gcgtgccaca
     5581 gacttggtaa agccaatcaa gccagcctta gaagcagcat agttagcttg accaatattc
     5641 cccatcaaac caacaacact agacatatta atgatagcac cttctctggc tttcatcatc
     5701 ggtttcaaga ctgattgtgt catattaaag gcaccagtca gattgacctt gagcactttt
     5761 tcaaaatctg cttctgtcat cttgagcata agagtatctt gggtaatccc tgcattgttg
     5821 accaaaacat ctactgaacc cagttctgca atagcttgat caatcatacg cttagcgtct
     5881 gcaaaatctg atacatctcc tgaaatggga accaccttga taccatagtt tgaaaactca
     5941 gcgagcaatt cttctgagat tgccccacga ctgtttaaga caatgttggc tcctgcttga
     6001 gcaaacttgt gggcgatggc aagaccaatt ccacgactcg aacctgtaat aaagatattt
     6061 ttatgttcta gtttcatttt tttcctttca aaacttctac ttattttagt ctatttttct
     6121 aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta agtgagcagt ttgatcaatt
     6181 tttttaacaa aacctgacaa gactttcccc ggtccaatct cgataaagtt gcttatgcct
     6241 gcttcttgca tgaccccaat actttcatag aaacgaacgg gttccttgac ctgacgcgtc
     6301 aagagctgag caatgtcctc tttttgcatc acagcagctt ctgtattgcc gactagggga
     6361 caagtaaaat ctgaaaaact tacctgagct agagtttcag ctagtttctg gctagctggc
     6421 tcaaggagag cggtgtgaaa gggacctgac accttaagag gaatcaagcg tttggcacct
     6481 gcttcttgca aaagttcaac cgctcgatca actgcaacca cttctccagc aatgacgatt
     6541 tgtgcaggtg tgttatagtt ggctggagta accactccaa gttcagaagc tttttgacag
     6601 gcttcttcaa tgacctctac tggcgtattg agaactgcta ccatcttgcc agagtcagca
     6661 ggagccgctt cttccatata ggctccacgc ttagctacca aggcaaccgc atcttcaaaa
     6721 tccaaggcgc cgcttgccac caaggcagag tattctccaa gagacaaacc agcaaccata
     6781 tcaggctgat agcccttttc ttgcaataaa cggtagatag caaccgaagt cgctagaatg
     6841 gctggttgcg tatagcgggt ctgattgagt ttgtcttctt ccgtatcgat gagataacgc
     6901 aaatcataac ctagcacctg actcgctcga tcaatcgttt ctttaacaat cggatactga
     6961 tcatagaaat cccgtcccat ccctagatac tgggcacctt gaccagcaaa taaaaaggct
     7021 gttttagtca tttcttacaa ctcctgtcca gcgagaggct tcttcttgaa ttttcttagc
     7081 ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt tcttctttag aaacaagccc
     7141 tgcgatttga cctgccatga cagagccacc ctccacatca ccgtgaacaa ctgctttggc
     7201 tagggcaccg gctcccattt gttcaaagat ttctaaatca ggatcttcct gcttaaaggc
     7261 atctttttca gccagttcaa aatctctagt caactgattt ttaatagcac gaacagcatg
     7321 accaaagtgc tgagctgaaa tcgtagtgtc aatatccctt gcttttaaaa ttttctcctt
     7381 gtagtttgga tgggcattcg actcttttgc aactacaaac cgtgtcccca cctgtacagc
     7441 ctctgcacct agcataaagc cagccgcagc accttcacca tccgcaattc ctcctgcagc
     7501 aataacagga atagatacag ctgtggctac ctgtcgcacc aaggtcatgg ttgttaattt
     7561 accgatatgc cccccagctt ccattccttc tgcaataaca gcgtctgcac cgattttttc
     7621 catgcgttta gctaaagcga cactaggaac gacaggaata acgattatcc cagcttcatg
     7681 gaaacgttcc atatacttgc ttggatttcc tgctcctgtt gtgacaactt taacaccttc
     7741 ttcaataacg agatccacga tatcttccac aaagggagat aagagcatga tgttgacccc
     7801 aaagggttta tcagtcaatg atttgatttt atcaatattg gccttgacaa cttctttcgg
     7861 ggcatttccc ccaccgataa ttcctaatcc tccagccttg gaaacagccc ctgccaaatc
     7921 accatcagca acccaggcca tccctccttg gaaaatagga tagtcaatct tcaataattc
     7981 tgtaatacgc gttttcatag tgcctccaac cttccttgct tacgtaatag ttcgatttca
     8041 ccataatttg acagtcaaac tattacctaa acaagaggga gtgggtttct ccctactcct
     8101 tctactaata ttctgcttat tttgcttgct cttcaacgta agcaaccaag tcaccaactg
     8161 ttttcaagtc attttctgct tcgatttgga tatcaaaagc atcttcgatt tctgagatta
     8221 cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa agttgattca agtgttactt
     8281 ctgatgcgtc ttttccaagt tcttcaacga taatttcttg tactttttca aatactgcca
     8341 tgataggact cctttaaaat aaatagtttt tttataacaa tgtgttcacc acatgattac
     8401 ctaaattgta agaatgagcg tgccccaggt caagcctcca ccgaagcctg atagaagaac
     8461 agtctggcta ccatctaaag ggatgagacc ttgttctaca cactctgaaa gtaaaatcgg
     8521 gatactggct gcactggtat tgccatattc catcatattg gctggaagtt tggctcggtc
     8581 aacaccaatt tttctagcca tcttatccaa aatacggtca ttggcttgat gaagtagcag
     8641 ataatccaag tctgtcacct ctataggaga ttcatcaata gtctgcttga tagacttggc
     8701 tacatctcga atggcaaaat caaagactgt gcgtccatcc atcttcaaaa atgaatctgc
     8761 actttcttga tctgaaaatg gagaatgcaa acctgaatgc ccataagtta aacactcgct
     8821 gcgacttcca tcgctattga gactctcagc taagaaatgc tcttgctcgc tagcttctaa
     8881 caagacacca ccagcaccat ctccaaacaa cacagctgtt gatcgatccg accaatcgac
     8941 tgccttagag agggtttcac taccaatcac caagcctttt tgaaagcgac cagaagcgat
     9001 aaacttttca gcagttgaaa gagcaaatac aaatccactg caagccgcgg ttaagtcaaa
     9061 agcaaaggct ttattagcac caatattagc ttgaacacga gcagctgtag agggcatcat
     9121 cgaatctgga gtaatggtag ctaggatgat aaaatccagt tcttctcctg ttattccagc
     9181 ttttgccatc agtttcttag caacctctgt agccaaatca ctggtagatt ctgttcttga
     9241 aatatgcctt tgtcgtattc ccgttcgact tgaaatccac tcatcattgg tatccataat
     9301 ctgagccaag tcgtgatttg taaccacttg ctctggcaca taatgagcaa cctgacttat
     9361 ttttgcaaaa gccattattt caaatcctcc aaaaattggt aaagattagt caagccttta
     9421 cccatgacag caatttcttc ctcgctcatg ccatcaataa ttttttctac catggccttg
     9481 tggaagcgtt tatgcagtct atgaatcaag cgacccttct ttgtcaaatg cagatgcacc
     9541 acacgacgat cctgttctga ccgaactcgc tcaatgtagc ccttacgctc taaattgttc
     9601 aaacttgtcg taacagttcc aagagttacc atcaactctt ttgacacttg acttggagtc
     9661 acatctggag ccttaccgat gacatcaatc gtatgcattt ctttgatgga gatatcctta
     9721 aaacgactac ctctcaagtt cacttcctca attacaagga cattgttaaa tatagatgtt
     9781 aaatattcat tgattcgttg gtagtccatt tttcatatcc ctccttctta aaaaaacttt
     9841 tacaatcaaa acatttgaca gaaagaatta tatcaaaatt caaagaatga tgcaagtatt
     9901 ttttattttc ctgtaaattt aggtcttctt ctctccgaat gagctcgcac tccttctttg
     9961 aaatcctctg tttgagctaa ggatttctgt aggttcagtt ctaaagtagc gtaaccctgc
    10021 cagtctttaa attggctctc ccaaaccaac ttcttaatgg cagcatagga attacttgaa
    10081 gcacgtctta attttttaag aagctgttct ctcgtctttt caagtttttc agcttcagaa
    10141 acgcggtaaa ccaaccccca ttctagggct ttttctgccg ttaaagcctc tcctgtcata
    10201 gctaattgag cagcacgcgt cacaccgata ctgcggctca agagatgaat tccccctgca
    10261 tctggagcca aaccaacacc aacaaaggct tggataaact tagccttatc cgtcgccaaa
    10321 cagaaatctg ccgcaacagc catattcgct gcggcacctg caacagcacc gtcaacttcc
    10381 attaaaacag gtttggctat ttgcttgatt ttataagaaa tcgtattgac caactctgcg
    10441 atttttgtca atgatggaat atcatcctca tccactgctc gcttcatctc taccaaatct
    10501 cccccaactg agaagacctt tccattggca ttgattaaga taaaatgcac agctggattt
    10561 tcttctgcca aagtcagagc ttctaaaatc tcctcacaca tgggaatatg aaaaccattt
    10621 gcgacctcag gacggttcaa ggtaaggatt gccaagtcct cttcaagttg ataaataatg
    10681 tgttccatca gggctccttt ttattttata agcagtttat actcttcgaa aatctcttca
    10741 aaccgcgtca gcttccatct gcaacctcaa aacagtattt tgagctgact tcgtctagct
    10801 tcctagtttg ctctttgatt ttcattgagt gttaaattat ttcactgtca aagtatatct
    10861 tttttaggat cagaaagcaa gaaaaaatcg actgaaagtg tctcagccga taagaaaagc
    10921 tcgctttagg ctagaaagca tcttattctc ttcattgaaa aaagcctttc tttctgctat
    10981 aatcgtataa aatacttact ttaggagttc ttatgaaagt tgttaaattt ggaggtagtt
    11041 ctcttgcctc tgctagtcaa ttagaaaaag ttttaaacat cgtcaaaagc gattcagagc
    11101 gtcgttttgt agtcgtttct gcgcctggta aacgcaatgc tgaagatact aaggttacgg
    11161 atgccctgat taaatactac cgcgactatg ttgcgggtaa cgatattagc aagagccaaa
    11221 gctggattat cgaccgctat gctgctatgg ttagtgaatt gggactaaaa ccagctgtgc
    11281 tagaaaaaat ttctaaaagc attcacgcct tggccactct tcctattgaa gaaaatgaat
    11341 ttctctacga tactttccta gcagccggtg aaaataacaa tgccaaattg attgctgcct
    11401 actttaacca aaatggtatc gatgcacgct atatgcaccc tagagaagct gggattgtgg
    11461 tcacaagtga acctggtcac gctcgcatca ttccatcaag ttatgacaag attgaagaat
    11521 tgacaaacac caatgaagtc cttgtcattc ctggtttctt tggtgtcact aaggaaaatc
    11581 aaatctgtac tttctcacgt ggaggttctg atattacagg ttctatcatt gctgctggtg
    11641 tcaaagctga cctctatgaa aactttacgg acgttgatgg tatctttgca gcccaccctg
    11701 gtattatcca ccaaccacac tcgattcctg agttgaccta ccgtgaaatg cgcgagttgg
    11761 cctatgcagg cttctcagtc cttcatgacg aggctcttct tcctgcctac cgtggaaaaa
    11821 ttcctctggt tatcaagaat accaacaacc ctgaccatcc aggtactcgt atcgttctaa
    11881 aacacagtaa tgatgaattt ccagttgtgg gaattgctgg tgactcaggc tttgtcagca
    11941 ttaacatgtc gaaatacctc atgaaccgtg aggttggatt tggccgcaag gttctgcaaa
    12001 tcctggaaga acttaacatc ggttgggaac atatgccaac aggtatcgac gatctttcta
    12061 tcattctccg ttctcgccaa ctaactccca tcaaggaaga agaaatcctg cgtcagttgg
    12121 ttcaaaaggc taaagtagat catgcagaaa tcgaacacga cctttctatc attatgattg
    12181 ttggtgaaaa aatgaagagc catatcggag tgactgctac tgcgacacgc gctctatctg
    12241 aaaacaaaat caacatccag atgatgtctc aaggttctag tgaagtttct attatgtttg
    12301 ttgtcaataa agaccaagag aaagcagcaa ttaaagccct ctacaatgcc ttttttggag
    12361 aaagtaagga agactaagca tggctcaatc acttaacaaa acagtactcc tcagtacgac
    12421 aggcacttcc tacctctcta tcgctgggaa agttgggaaa ttccttgtcg gagatcaggc
    12481 tttggaattt tacccagatg tcaatgtcga acaatttatc cagattcctt ggagccatat
    12541 caatcagatt ggagccaatg tcactggacg caaaatcagc cgccacttcg aagtctttac
    12601 agacaaagga aaattcctct ttgcttcaaa agactcaggt gccattctca aaattgcacg
    12661 cgaaaaacta ggcaatgaca aggtcgtcaa acttccgacc ctgattcaga caattagcca
    12721 aaaatttaaa aatctatttg caaaaaagta gaaactttag tataatcata gcaacggata
    12781 agtaggttat cttcttcttt cagaaagtct gcgggtactg cgagcagata ggagggatag
    12841 gtgaaattct accgttagta acaattacat acacaatcaa gtgcacacct gtgaagttgg
    12901 atggaaccgt ggccctgcca ctccaacgtt ttgtcaggcg tgcttttttc ataaaggagt
    12961 tcttatgtta gatatcaaac gtattcgtac agattttgaa gctgtcgcag aaaaattagc
    13021 tacacgtggt gtagatgctg ctgtcttgaa tgaaatgaaa gaaatcgatg ctaaacgtcg
    13081 taacatcttg attaaggttg aaactctcaa agcagaacgt aacacagttt ctgctgagat
    13141 tgcccaagct aagcgcaaca aggaaaatac agatgacaag attgctgcca tgcaaaatct
    13201 atctgctgag gttaaagcct tggatgctga attggcagaa atcgatgcta aattgacaga
    13261 atttacaacg actcttccaa atatcccagc tgacagcgtt cctgttgggg ctgacgaaga
    13321 cgacaatgtg gaagttcgcc gttggggtac tccacgcgag tttgacttcg aacctaaagc
    13381 tcactgggat ctcggtgaag accttggtat ccttgactgg gaacgcggtg gtaaggtaac
    13441 aggcgctcgc ttcctcttct ataaaggcct cggtgctcgt ttggaacgtg ctatctacaa
    13501 ctttatgttg gatgaacatg gaaaagaagg ctatactgaa gtcatcacac cttacatagt
    13561 caaccatgat tctatgtttg gtactggtca gtatccaaaa tttaaggaag atacttttga
    13621 actcagcgat accaactttg tcttgattcc aactgctgaa gttcctctga caaactacta
    13681 ccgtgatgaa atcttagacg gcaaagatct tccaatctac ttcactgcca tgagtccgtc
    13741 attccgttct gaggctggtt ctgccggtcg tgatacgcgt ggcttgatcc gtttgcacca
    13801 attccacaag gttgaaatgg tcaaatttgc caaaccagaa gaatcttacg aagaattgga
    13861 aaaaatgaca gccaacgctg aaaacattct tcaaaaactc aaccttccat accgtgtcgt
    13921 tgctctctct actggagata tgggcttctc agctgcgaag acttacgact tggaagtgtg
    13981 gattccagca caaaacaatt accgtgaaat ctcaagctgt tcaaacacag aagatttcca
    14041 agcccgtcgt gcccaaatcc gttaccgtga tgaagcagat ggcaaggtga aactccttca
    14101 taccttgaac ggttctggac ttgcagttgg acgtacagtg gctgcaattc ttgaaaatta
    14161 ccaaaatgaa gatgcttctg tgaccatccc agaagcactt cgtccataca tgggtggagc
    14221 tgaagtcatc aaaccataaa aaataaggtt tagctatttc tagctagacc ttttttcgta
    14281 accaaatcag ataagcacct agtacaaaga ataaaatagt taggcatata atggtttcag
    14341 ccaataccag gtaatccaga aatggaagtt tcaaaattcc ctgagccatc ttgagcgagg
    14401 tcgctgtgat aatggttggg aaggtgaggg ctgagaaggc tggttgaaaa ccttgtttta
    14461 aaatgttggg cagacgagtt aaaacaaaga aaaagaagga ttgagaagcc aaaatcatga
    14521 caatcaagac ccaagtcggc aggctggttc ctcctactcg aactagagaa gccaagagta
    14581 gagagaaagg agcacagtag attccttctt gtccaagcaa ggctagtggg agtggatgtt
    14641 tctttaaatc gctataaata aggggataga gatagaaggt caagagaaaa ccaaaactca
    14701 aggtcgcata ggcaatttcg ataataccta ccagaggata ggtcaaggca gccactgcta
    14761 tccccacata gagaaccgtc caacttggag tggcatgaac cctccgccct ggacaagcaa
    14821 acttgatggt aaaaccagca atcaaggtca aatccaagag aaatgaaaac caccaaatcc
    14881 cttgtgctac caaaggaaga taagagaata cgcgaaagac ataggtcgat aaaatcatcc
    14941 cagccatagg aaaggttgcc attcctgaca aaagaggggg cttggtcaat tcttgcttgg
    15001 tttctttcca attaaagaga tgcagaatta gaaagtaaat ccataaaacc aaaccagtca
    15061 gactaaaaag atgggataga accggcaacg tatctaaaat aagatttcca gctcctgcca
    15121 aacctagcaa acaacctgaa aatactaagg ggagtttttt catcctaacc tccaataatc
    15181 atgttagttt cagtataaca taaaagcgct taaatgagga tttaaaaaaa cgaagtccgc
    15241 ttatttcaga cttcatttta ctcagatatg aattaggcat aaggttgcaa ttctggatta
    15301 attggtgtat tagctaagtt gttggcatag ttacagagga ttgctaggct gacaccaaaa
    15361 accacatcca aggcattttg ttgagtgtag ccagcttcta aaaactcaga caaggcttca
    15421 tctcctacac gacccttggt attgataact gccaaggtaa acttagctag ggtatccaat
    15481 ttaggatctg tttcaattgg agtacgattg cgaagagctt gaatcaagtc atcattcatc
    15541 tggatttgtt tgatggaaaa ggctgtgtga cctgcgacac agaaggcaca accattggtc
    15601 acggctgccg tgatttgcac cacttcacgc tcaacgggtg tcaggctgtt gcgacggtgg
    15661 atagatgaga caatttgata ggcttctaaa acagtcgggg cattggccaa gagaccgatt
    15721 aggttgggaa tatagccatt gttgtctttt tctactgttt caagaatttc tttcacttct
    15781 gctggtgctg actctactgt atggatagta aatgttgtca taagatacct cttttcttat
    15841 tattgacact aatattattg gaaaatctta taaaatcctg attcctaagt ttatctaaga
    15901 taaagcttta ttctctcata agattttcgt tgttatatta gtttatcaca cttccaatca
    15961 cttgcataat atatattata tatcaggctg ataaaaatta tttataggca aaaaaatcac
    16021 acgaactgtg tgattccatt atttgtcaaa atacttttta gtttcagcaa taacgactgg
    16081 cgacaagacc aagagggcaa tcaagtttgg cagagccatc aaggcgttaa cgatatctgc
    16141 gataatccag accatatcca actcgataaa tcctcctaac aagaccatga gcacaaaaac
    16201 cacacggtag agccagataa agcgaacccc aaagaggaac tcaaaacagc gttctccgta
    16261 atagttccaa cctagaatcg ttgtaaaggc aaaaagtaca aggaagatgg tcaagagggc
    16321 aggcccaaag tgtgaaaaga ctgttgagaa agctgactga gtcaaggcaa ccccattcaa
    16381 gtcaccactc caaactccag ttaccaagat ggtcaaacca gttagagtac aaatgatgag
    16441 ggtatcaata aaggttcctg tcatggaaat caaaccttgc tctactggtt catttgtctt
    16501 ggcagctgca gctgcaatag gagcagaacc cagaccagat tcgtttgaga acacaccacg
    16561 cgccacacca ttttgaatag ccatccgaac gctagcacca gcaaatccac ctaccgcagc
    16621 aaggggacta aaagctgagg taaagactaa agcgattgtg ccagggattt ttccgatatt
    16681 aaagaaaata actgtaagag ttcctaagat ataaatgatg gccataaaag gaacaacagt
    16741 agttgaaacc ttagaaatag acttgagtcc accaaagact gcaatcgcta caaagacaga
    16801 caagacgaga gctgtgatgg ctggcgaaat cgtcgttgta ttttggatag attctgcaat
    16861 cgagttgact tgggtgaagg ttccgattcc caagagagca accaatactc ctgctactgc
    16921 aaacaaaaca gcaagtggtc gccacttttc tcccatccct agaaggatat aatgcatggg
    16981 acctcccgct actgcaccat ggtcgtcctt ggtgcggtat ttgatggcca agagtccttc
    17041 cgcatacttg gtagccattc caaagaaagc cgccatccac atccaaaata gagctcctgg
    17101 tccaccaacc ttgatagccg tcgcaactcc tatgatattt cctgttccaa cagttgatgc
    17161 caaggctgta cacagagctg caaaactgga tacatcacca tgtcccttat cctggataaa
    17221 aataagctga aaagccttgg gcagacgcaa aacctgcaag agtcctagcc gaatagttag
    17281 gtaaatccct gttccgacca ataaaatcaa gaggggcggt ccccaagcaa aagcatcgat
    17341 tgatttaagc aattctaaca tttccttctc ctatcgtttc aaccccaaaa gaaagagcac
    17401 atgcaagata catgtactct ggaatgctta gataaatgct aaaaagcggt ctatcctagc
    17461 tctgtccttt tacctgagag tttgagcagt tgcctgcctt gccccttcgg tgcctttacg
    17521 gtctctccag agttccgtcc atttacagtc atggaaaatc aaacgattcc ccacttctat
    17581 taaacttcat tcggtgttgg tatttaattg attctaattt tacaaaaaat gttggctttt
    17641 gtcaatgtgt ttattagtaa aaattagttc aacagttttt actttataaa gtccagaata
    17701 ctgctatcct ttaaaagtga caatagtcgc accactgcct ccagcatttt gtggggcata
    17761 gccgaaactc ttgacatgtt tgtttctttg caagtatttg gtaactcctt cacggatgac
    17821 tcctgttccg ataccatgga tgatatcaac ttgagccata ttgttaagca aggcttggtc
    17881 gatgaaggta tctagctcat tcatggcttc ttcatagcgc ttgcctcgaa gatccagtct
    17941 agcttgaggt cctcgcccag aagttcgttt cacaacattg acctgtttct tcttgactgg
    18001 tttttcttgc tgggcttgaa caagatcaaa ctctttctct tccaaggtca tcttaatcaa
    18061 gccaacttgg gcttcccagc ggccgtcctt gagttgactg gtcaaggtac cacgctgacc
    18121 ataactgaga accacgatat catctcccac ctttggagct cgttttttct tggccttttg
    18181 aaggaccttg tttttagaca agtccacttt ttcaggagcc aattttttca acttggcctt
    18241 ggcttcaatg atttcgtggg gcttgagttg ggatttactg tggagatttt tgagaatctg
    18301 gtcactttca cttagggcca tatccacaat ctcagcagcc tgttcacgcg ccttgttaag
    18361 ctcgatttcc ttttcacgat taagctcgtt gtagagtttt tttagcgcac ggttcatctt
    18421 gagattttct tgctccacct cacggatatt gtccaagcgt ttgcggcttt ccagcgtctg
    18481 ctcttctaat tgctcaatga tacgattgac gtcattgtcc tgatcgatct gctgactggc
    18541 atctcctacg ataacttcag ataggcctag acgtttggca atttcaaagg cattacttcg
    18601 gccaggaaca ccctgcataa agcgataggt cgggcgaaga gttgcagtat caaactccat
    18661 actggcattt tgcacaaagg ctgtctcaat accgtaggcc ttgagttctg gatagtgggt
    18721 cgtcgccatg gtcttgattt gacgcaggcg aaggtcctcc agaatagcca tggcaagggc
    18781 tgctccctct tggggatcag taccagcccc caactcatcc aaaagtaaga gtgaatgttg
    18841 gttgaccttg ccaagaatat ccacgatatt ggtcatatgg ctagagaagg tagacaagct
    18901 ctgctcaata gactgctcat ctccaatatc agcaaagatt tcttcaaaaa taccaacacg
    18961 acttcccttg tctgctaaaa tcggcaatcc tgactgggcc atgacctgtg tcaagcccag
    19021 agttttgagc atgatggtct tcccacctgt attgggacct gtaatgacaa tagctgttaa
    19081 atcttgacca aaatagacat catttgcgac ggcatttttg accaaaggat ggcagacatg
    19141 gagcagttga atctcttgat tttctgacag ctgaggcacg actgcttgtc tttcttggat
    19201 aaatcgaacc ttggcacgaa tcaagtccag atgaccgata atccaagcgt cattagcaat
    19261 ctcagccgca tgagggcgga cacgctcaga aatttcttgg agaatgcgaa gcatttcata
    19321 gcgctcatct gctcgcagac tagcaatttc ttcgctcagt ttgactacct cacgtggttc
    19381 gatatagacg gtgtttccac tagcagaaat atcatgaacg acacctgcaa tcttattgcg
    19441 gtaggtgttt ttgactggta aaacctgacg gccatttctg ctagcaacaa ttccttccgt
    19501 caacatctgc gctttttgct tgagcaagtc ttgtaaaaca tcgcgtacct gactctcgct
    19561 atcatgtatt tttcgacgga ttcgcgccaa ttcttcactg gcaaaatttt caatgaaacc
    19621 cgcatcatta aaggcctgaa gatttccttg taattgcgga aaatcatgta atttctcaaa
    19681 ccaaagggct aattcttcca agctgacatt ttccagattg gcgtaaaaac tttgaagttc
    19741 tcggctggta agaagcacgc gtttcaagag taggaactcc tcgatattga gatccgctcc
    19801 catctccaac ctcttgcaga ctcctgcaat ttccttagtt gagagaatag taaaatgcgg
    19861 ttgctcgacg aaaagagcct gcatttcttt catctcagca aaagcctgtt tgattttatc
    19921 tgctttggca gtcggagcca gctgtctcaa ttgctccaag ccctgctcgg tcaacaaatg
    19981 aggctcaaac aaggccttga ccttatcgaa ctctaatgtt tctaatattt tcttattcat
    20041 ctttatttcc ttgtctttga atgtctaggt gtggtagctt tttacattct gatagattcg
    20101 agtcaaatct gtaaacaaag ggctaggaaa actcctgccc tttttatccg attaaatttg
    20161 tcacccagat ttgtttgagc caactggttg ttatcggtat gctctggatg atgtgttttg
    20221 cgacgatact cttttcaaga ggattttgta taactgccat ggggatggtc gccaagattg
    20281 tcaaggccat ttgcaagaca aataaggtca ccaacatgga caagatacct gctgaaactt
    20341 ggaacaactt accacccagt tttttgctag gaatcaagtg taagagaaga ccaagcaaac
    20401 gaccaatgct atagacaatc ccaaatacaa gcaagtagcc gatacctgca taaaagacct
    20461 tatccagctg aaagagttga tccgatggga aaaagaaagt cccctgacct tcctgcgaat
    20521 ttgcataagg gagcaataaa tggaattgct ctccaagccc cttataaaac tggccagcca
    20581 taaaagccga tgccatggct gaaatcaggt aataaacctg taagagcagg cctctccgat
    20641 agccgatata aaatccccaa accaagacca atagaagaag gaatgaaatc ataaggaatc
    20701 ctcaatcttg ctctgttctt gcttacaagt cacaagcttg tgacggagtt cttctagctc
    20761 ttgctcctta tcgtcaaatt caatctcacg gctgagctga gttgataaac agttgactgc
    20821 caacaaaaga gcgattgttt catcatctgc gctaggcatt tgttctttaa ttgcttggta
    20881 tttttctgtc gcaaccttag cgatttcctc cataaaaagg ttgtcatgtt cgcttgtcaa
    20941 ggttaacgat tttttcccga atgtaaattt gaatcgattt agatttgcca taaaattcac
    21001 ctcacgatat tataccaaaa ttcgctaatt ttgtcagttt ttacaaattt tactgctttt
    21061 gtggtacaat agaaactatg gcaagtatca cactcacacc aagcgaaaag gatattcagg
    21121 cttttcttga acactatcaa accagtctgg ctcctagcaa gaatccctat atccgctact
    21181 ttttgaaact acctcaagca acggtttcta tctatacttc tggaaaaatc ttgcttcagg
    21241 gtgaaggggc tgaaaaatac gccagtttct ttggctatca agctgtagag caaaccagcg
    21301 gacaaaatct tcctttgatt gggacagatg aggtagggaa tggttcctac tttggtgggc
    21361 ttgcagttgt ggcttccttt gtcacacctg accagcatgc cttcttacga aaactcggtg
    21421 tgggagattc taagactctg accgaccaaa agattcgtca gattgctcct attctcaagg
    21481 aaaaaattca gcaccaggca ctccttctct cacccagcaa gtacaacgag gtcatcggag
    21541 accgctacaa tgctgtttcg gttaaggttg ccctccataa tcaggctatc tatctcctcc
    21601 ttcaaaaagg tgttcagcct gagaaaattg tgattgatgc ctttaccagt gctaaaaatt
    21661 atgacaagta cttggcacaa gagaccaatc gtttcagcaa tcctatcagc aatcctatca
    21721 gcttagaaga aaaggctgag ggcaaatact tggctgtcgc agtttcttct gtcattgcgc
    21781 gtgatctctt tctggaaaat cttgaaaatt tgggacgaga actgggttat cagcttccaa
    21841 gtggagctgg aacggcttct gacaaggtgg ctagccagat tttgcaagcc tatggtatgc
    21901 agggactcaa cttctgcgcc aaattgcact ttaaaaatac tgaaaaagcg aaaaacgctt
    21961 agaaaggtaa gttatgaatt tatttaaaaa tttcttaaaa gagtggggat tattcctcct
    22021 gattctgtca ttactagctt tgagccgtat ctttttttgg agcaatgttc gcgtagaagg
    22081 acattccatg gatccgaccc tagcggatgg tgaaatcctc tttgttgtta agcacctccc
    22141 tattgaccgt tttgatatcg tggtggccca tgaggaagat ggcaataagg acattgtcaa
    22201 acgtgtcatc ggaatgcctg gcgataccat ccgttacgaa aatgataaac tttacatcaa
    22261 tgacaaagaa acggacgagc cttatctagc agactatatc aaacgcttca aggatgacaa
    22321 actccaaagc acttactcag gcaagggctt tgaaggaaat aaaggaactt tctttagaag
    22381 tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac tacaacacca actttagctt
    22441 tactgttcca gaaggagaat accttctcct cggagatgac cgcttggttt cgagcgacag
    22501 ccgccacgta ggtaccttca aagcaaaaga tatcacaggg gaagctaaat tccgcttctg
    22561 gccaatcacc cgtatcggaa cattttaaga gacctaagag gccgagaatc accaatctca
    22621 gcctcttctt ctatcgtgag aaaatgattg gtaactatct aaacttacca gaacagaaac
    22681 acctcaactc tcacctattc atgcaaagga attttatgga agtttatttt tcaggaacca
    22741 ttgaacggat tatttttgaa aatcccagca atttttatca catcctcctc ctagaaatcg
    22801 acgatacgga cgcagaggat tttgatgatt ttgaaatcat tgtcacagga accatggctg
    22861 atgtaattga gggcgaagac tatacttttt gggggcaaat tgtccagcac tccaagtatg
    22921 gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag ggcttggtca
    22981 agtacttttc aagtagccat ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg
    23041 atacctatgg cgaaaatacc attgacgaaa ttttgcaaca cccagaaaag ttagaaggca
    23101 tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt ctcaactacg
    23161 gaacggagat ggttttggcc aaactagcca actacggcat tcccaacaaa ctagcctttc
    23221 agattcaaga cttttacaag gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc
    23281 tggttgagga tatcaagggt ttgggcttta ccattgctga ccaactagct gaggaactag
    23341 gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct agttcacagt ctttttcagg
    23401 cctgtatgga aacaggggac acctatgttg aagcacggga tttgctggaa caaaccctta
    23461 ctctccttga gtcttcccgt cccgtggaac tagaccccag ccaagttgcc caagagctct
    23521 cctacctgat cgaagaagac aaggttcagc agattgatac caagatcttt gacaacagcc
    23581 tctttttcgc tgaggaaggc atccgcagtc acttggttcg tatccttgaa aaaggaaaac
    23641 agaagagtca tgatttaaaa accattcaaa aacatatcac tactatcgag aaagagcttg
    23701 gaattgagta tgataacatt caaaaacagg ctatctgtga tgctatccag aataaggtct
    23761 ttatcctgac aggtggacct ggtactggta agacaactgt tatcaatggg atcatcgctg
    23821 tttacgccct gttagaggga cttgacctca ggaagaaaag caacctgccc attcttcttg
    23881 ctgctccaac tggtcgagct gctcgtcgca tgaatgaatt gacaggtttg cctagcgcga
    23941 ccatacaccg ccacttggga atgacaggtg acgatgatac cagtcatctg gaagattacc
    24001 tagatgctga ctttatcatc gtggatgaat tctctatggt ggatacttgg ctggccaatc
    24061 aactcttctc cagtatctct tctaacagta agatcctcat cgtaggtgac agtgatcagc
    24121 taccttctgt cagtcctgga caggttctag cggatctgct tcatattcct ttgattcctc
    24181 agactcgctt ggaaaaaatt tatcgacaaa gcgaagaatc aaccatcgtc accctagcta
    24241 gtcagattcg acagggcatc ttgccagctg atttcaccca aaaaaaagct gaccgttcct
    24301 actttgaaat tgctagtggc catattcctg ccaccattga aaaaatctta ggtgccgccc
    24361 tcagaaatgg tattcctgcc cgtgatatcc aagttctggc tcctatgtac cgagggacgg
    24421 cagggattga tgctatcaat cagctcatgc aagacctgct caatccccca caaaaagatc
    24481 aactcagttt tgaagctcct cagtgccact atcgtaaggg agacaaggtc attcatttgg
    24541 ttaacgatgc tgaaatcaat gtctttaatg gggatttagg agctatcaca gacctgattc
    24601 ctggtaaata caccgaatcg aaacaagacg agattgtcat tgattttgat ggtaatgaag
    24661 tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg agtattcata
    24721 agtctcaggg aagtgagttc ccagttgtca tcctaccgat tactagtgct agccgacgta
    24781 tgctggagcg aaatctcatc tacacagcca ttacacgtgc caaaagcaaa ctcatcttac
    24841 taggcgaatt acaagccttc gactatgcta cccaacacat cggaactgcc cgaaaaacct
    24901 atctgattga acgcttcagt gatctactgg agaatgttga agaaaagcaa caagctgtct
    24961 ctgaaacagt cacatcaagt gcctctgaac aatcctacat cctaaccgaa gaaaactggg
    25021 acagcattcc agccatgatt gggattacag acacagacct caaagagatt tttggaaaat
    25081 agtacatcag aaaacccacc aattcaggtg ggttttctgt ttattaagat tattttactg
    25141 ttgctgtgct tgtgatcaat tcaacagctt ttttgatagt gatatcatgt ttcaacatgt
    25201 cagctgaaag caagttttga acttgtgcaa cttccatgtt gtagtctgct gccaattgct
    25261 caacttcttt ttggatttct tcttctgaag catcaaatcc ttcagctttg gcaactgctt
    25321 cgataacaag gttagtctta gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt
    25381 cttcttgagt agttccagtg atttggaagt acatgtcagg gttgatccct tgacgttgca
    25441 agttcccaag gaattcattt actgaacggt gaacttcttc atggatcatt tcttctggaa
    25501 gttctacgat ttcagcgttt tctacagctg tatcaattgc tgcaccttca actgcatctt
    25561 tgtaagcttc ttctttagca gcagccaatt ctttgcggta tttttctttc aagtcagcaa
    25621 gtgtttcaac ttcttcatca atgtcttttg caagttcatc gtcaagagct ggaacttctt
    25681 tagcttttac ttcgtggata gttgtcacga atttagcttc tttacctgca aggtcttctg
    25741 cttggtagtc ttctgggaat gttacgataa catcaacggt ttcgccagct gagtgaccta
    25801 ccaattggtc ttcgaaacca gggatgaatt gacctgaacc aagtccaagt gagaagtttt
    25861 caccttttcc accgtcaaat tcaacaccgt cgatagaacc aacgaagtcg atcacaacag
    25921 tgtcgccgtt ttcagcagca gcttccttga taaccaattc agccaggttg ttgcgttcgc
    25981 gttcgatacg ctcttcaaca tcagcgtcag ttacttcttt ttctacatca actgatactt
    26041 caaggttttt gtagtcaccc aattttactt caggttttgt aacgacttca gcagcgataa
    26101 cccagtcttg acctttttcc attgaagtta cgtcaatttt tggttgggca accacttcaa
    26161 gaccagcttc ttttacagct gcttcataag cgtttggcaa aagagcgttc ataacgtctt
    26221 ggtaaagtga ttcttcacca aattttttat cgaagatagg acgtggaagg tgacctttac
    26281 ggaaacctgg aacattaaga gatttcttca ctgacttgaa gacacggtcc aattctggtt
    26341 tgatttggtc ttgagagata gtgaaagtca agacaccacg gtttgtttct ttgttttcaa
    26401 atgatacaga cattctgtca tttctcctta aaatttttta aatacagtct attataacat
    26461 tttctataaa taaaatctag a
//
LOCUS       DAVKZI010000029        26423 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKZI010000029 DAVKZI010000000
VERSION     DAVKZI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.030"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            32..202
                     /locus_tag="VXB18_001424"
     CDS             32..202
                     /locus_tag="VXB18_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382610.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            652..2667
                     /locus_tag="VXB18_001425"
     CDS             652..2667
                     /locus_tag="VXB18_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0382611.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNIGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2669..3301
                     /locus_tag="VXB18_001426"
     CDS             2669..3301
                     /locus_tag="VXB18_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382612.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4246..4659)
                     /gene="ndk"
                     /locus_tag="VXB18_001427"
     CDS             complement(4246..4659)
                     /gene="ndk"
                     /locus_tag="VXB18_001427"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0382613.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(4770..8447)
                     /gene="rpoC"
                     /locus_tag="VXB18_001428"
     CDS             complement(4770..8447)
                     /gene="rpoC"
                     /locus_tag="VXB18_001428"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0382614.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NKETTEVVVDTAVETVEETVE"
     gene            complement(8480..12091)
                     /gene="rpoB"
                     /locus_tag="VXB18_001429"
     CDS             complement(8480..12091)
                     /gene="rpoB"
                     /locus_tag="VXB18_001429"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0382615.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12507..12577
                     /locus_tag="VXB18_001430"
     tRNA            12507..12577
                     /locus_tag="VXB18_001430"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12539..12541,aa:Cys,seq:gca)
     gene            complement(12775..14106)
                     /locus_tag="VXB18_001431"
     CDS             complement(12775..14106)
                     /locus_tag="VXB18_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0382616.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14397..15221)
                     /gene="endA"
                     /locus_tag="VXB18_001432"
     CDS             complement(14397..15221)
                     /gene="endA"
                     /locus_tag="VXB18_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0382617.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15260..15448)
                     /locus_tag="VXB18_001433"
     CDS             complement(15260..15448)
                     /locus_tag="VXB18_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0382618.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15441..16724)
                     /gene="murA"
                     /locus_tag="VXB18_001434"
     CDS             complement(15441..16724)
                     /gene="murA"
                     /locus_tag="VXB18_001434"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0382619.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16748..16978)
                     /locus_tag="VXB18_001435"
     CDS             complement(16748..16978)
                     /locus_tag="VXB18_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0382620.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17036..18073)
                     /locus_tag="VXB18_001436"
     CDS             complement(17036..18073)
                     /locus_tag="VXB18_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0382621.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18057..18545)
                     /gene="coaD"
                     /locus_tag="VXB18_001437"
     CDS             complement(18057..18545)
                     /gene="coaD"
                     /locus_tag="VXB18_001437"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0382622.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18535..19074)
                     /gene="rsmD"
                     /locus_tag="VXB18_001438"
     CDS             complement(18535..19074)
                     /gene="rsmD"
                     /locus_tag="VXB18_001438"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0382623.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19139..20131)
                     /locus_tag="VXB18_001439"
     CDS             complement(19139..20131)
                     /locus_tag="VXB18_001439"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0382624.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20242..20925)
                     /locus_tag="VXB18_001440"
     CDS             complement(20242..20925)
                     /locus_tag="VXB18_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0382625.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFSELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20981..21721)
                     /locus_tag="VXB18_001441"
     CDS             complement(20981..21721)
                     /locus_tag="VXB18_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0382626.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            21755..22033
                     /locus_tag="VXB18_001442"
     CDS             21755..22033
                     /locus_tag="VXB18_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0382627.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22111..23037
                     /gene="yidC"
                     /locus_tag="VXB18_001443"
     CDS             22111..23037
                     /gene="yidC"
                     /locus_tag="VXB18_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0382628.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23112..23906)
                     /gene="pflA"
                     /locus_tag="VXB18_001444"
     CDS             complement(23112..23906)
                     /gene="pflA"
                     /locus_tag="VXB18_001444"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0382629.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24032..25282)
                     /locus_tag="VXB18_001445"
     CDS             complement(24032..25282)
                     /locus_tag="VXB18_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0382630.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25349..26176)
                     /gene="purR"
                     /locus_tag="VXB18_001446"
     CDS             complement(25349..26176)
                     /gene="purR"
                     /locus_tag="VXB18_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0382631.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
BASE COUNT         7618 a         5894 c         5178 g         7733 t
ORIGIN      
        1 aaaaacaagg aaaaagaaaa gggtttcacg aatgaagaaa aatcgtggaa ttcaaaaatt
       61 agctatatta gtattactag gtgtttttat gtttagtaac acaattcctt accaacagtt
      121 tattcagaag aatagacaat tggagattcg agtgcaatca caaaagaagt ccaatggtct
      181 tgatgttggg aaggctgatt gatttcgtat tactttaaaa ttcaactatt tagagaaagg
      241 tattctgatg agagcttgta acaataccag atagatataa gaatggagat gtttgataaa
      301 atgctttcat agctaaccaa ctgttgaaaa ttatgagtta caaaatctaa agtatttaag
      361 attggtttat aaaattaggt ctctgcctgt agaaaggaac gtgcagttag aaaggaggaa
      421 aaaataggat actataattc agactgagat ttctaattaa aatatgtagt tgcatttcgc
      481 tcattttcat aatatttcat tcagaggagt aataatatgt taaaatttag atttgatgcg
      541 ggatggtaaa gaataattga agaagattct tttatcaata gtttagtaag cttgttagtt
      601 tatagagggc aggggtattt ctgccctctg ttttagaata aggaatgcac tatgaaaaaa
      661 ttatttatac tcatatccaa cctgcttgct agtttgttct ttgtttgggt atttaccatt
      721 tggactgata catatgtctc ccattattac cccaacgttg ttgtacgtga ttcttcccct
      781 gaaacaactt ttcagcatgt tgctacacgc ttggaaaaac tagcagaaga aacagatagc
      841 tttattgcga ttcaacacca agatcctaac tcagaaggta ctacagtttt ttcttatacg
      901 acctttgggg acggaaagtt gcctgatggg cttcaggaaa aaaatctaga agatgctcaa
      961 agtagtagtg ttgaaacaaa ctattttgta ttcgatggac acctagatat tcacttgcta
     1021 agggaagagc taagtcaact tggcttgact aacatgcacc tgacaattcc atctaaacta
     1081 tctacgttaa tggctatctt tagtaacgga tttcagttaa tcagtctatt gattttcatc
     1141 ttaacctttg tagcactgac tttaattagt caaattagcc aattacggtc atcgggcatt
     1201 cgcctcattt caggagagaa acggtggtcc attttcctta gaccagttgg tgaggatttg
     1261 aaagcgatag ctgttggttt cagtttagct ggcgtgctcg ccattcttat gcaaaaaatt
     1321 ctgtcgcttc caacgcaatc cctaatgacc ataggagcag gcttgctcag ttataatctc
     1381 atcttgttgt cgatctccct gtttttcgct caactcttcg cagttgggat aaaaaagata
     1441 cacctgatgc agattataaa agggcaagtg cctgtcagag gaatcattag tttgatttta
     1501 atcggtcaac tattagcgat tattattgta acactgggaa tagggagtag cttaaagtat
     1561 tcccaagcct ggcaacagca tcggattgga caagaggctt ggagtcagga aaggcaactg
     1621 attaccctat caatcagccg tgaaggaacg agtcctggtt ttgatgaaca agctcaaagg
     1681 aaactcagaa cttggtatca attgatggat ctggctgttt cagaacaaaa ggctttctta
     1741 tctagacacc agttaattga ccgtactttg caaaatggca tggcttcctc caaaaacttg
     1801 ataacctcta cagaatggca cgattacaac ccgaatggca atgtccttat cgtcacaccg
     1861 caatacttgg agcgtcaaaa cattcctgta gatacaacta ttgagcaaaa gatgaatcac
     1921 cttaatatag gggagtttgt cttattgcta cctgaacacc tccgttcaga ggaagaacat
     1981 tataaatctg tttttgaaga cgacttaacc agtcgcatgt ctagtcaaga tgaacgacag
     2041 caaatgactg ctacggtagg ttatttggaa tcaggtcagg atcgatttgt gtataatacg
     2101 acccctattt cttaccagca gtttttgaaa gatccaatca tcattgttat aacaccccaa
     2161 tcaactggtc cacagtccat tttgttttgg atagacgcag tacagaacta cgttctcttt
     2221 aatcaattgt ctgatgccca ggagcttatc cagagacaag gcattgaaaa ttgggtctca
     2281 gaaatgcaaa caggttacca caactacatc acattattgg ataatatcca gagggaacgt
     2341 tgggtaatgc tagcaggagc tgtgcttggg attgcaactt caatcttgtt gtttaacact
     2401 atgaataggc tctactttga agaatttaga cgtgccattt ttatcaaacg cattgcaggt
     2461 ctcaggttct tagaaatcca tcgcacttat ctctttgctc aactgggtgt gtttttactg
     2521 ggatttgttg cgagtgtatt tcttcaggta gagataggag ttgctttctt agtcttgtta
     2581 ctctttactg gtctatctct tttacagtta catgtccaaa tgcagaaaga aaacaagatg
     2641 tccatgcttg ttttgaaggg aggttaatat gattgaactt aaacaggtga gtaaatcttt
     2701 tggagaacga gagttatttt cgaatctttc aatgacattt gaggctggaa aagtctatgc
     2761 cttaattggt tcaagtggta gcggaaaaac aaccttgatg aacatgattg ggaaattaga
     2821 accttatgat gggacgattt tttaccgagg taaagacttg gccaattata aatcaagtga
     2881 ttttttccgt cacgaattgg gctacctctt ccagaacttt ggcttaattg aaaaccaaag
     2941 tattgaagaa aaccttaagc taggtctcat tggtcaaaag ttgagtcggt cggaacagcg
     3001 gttgaggcag aagcaggctt tagaacaggt cggcctggtt tatcttgacc tagataagcg
     3061 catctttgag ttatcgggcg gagaatcgca acgggttgcc ttggcaaaaa ttatcttaaa
     3121 gaatccaccc tttattctgg cagatgagcc aacagcttca atagacccag caacctctca
     3181 gttgattatg gagattttgc tatctcttcg agatgataat aggctaatca ttatcgcaac
     3241 acataatccg gcaatttggg agatggctga tgaagtgttc acgatggatc atctgaaata
     3301 aaaatccttg tttttaattg cacgatgagt tactgaaata ttatcatgaa tcaagaattg
     3361 gagttaattt agaattgtac tttattaata ttgaggtaac tttttcttga taaaggaaga
     3421 aataatggag aggaagttag aatggagagg aagttagaat gaaaaaattc gacaattata
     3481 ttattgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
     3541 gtttggtaga tgatattttg caattttctc tcagaatcaa taatagtgta ggagagattt
     3601 tcctcctaca accgttttaa aagaaaacta tctttattcc atgttatttt gaggaagata
     3661 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
     3721 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtagct
     3781 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
     3841 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
     3901 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggataaa
     3961 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggattgaa cacctttatt
     4021 gtatcgcgtt tggagttttt ttggtataac cttcgacgca cacccgcata gcgggtgttt
     4081 ttttgtctcg cacctaacgg agcgagacaa actaatagtc acttaatcaa aaaacgcacc
     4141 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
     4201 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
     4261 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataatctc
     4321 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
     4381 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
     4441 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
     4501 caagtcctga tagtgctggt caatcaactc ttctgaaacc tgtgaacgaa actccaattt
     4561 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gtcctctttt
     4621 tacaccatct ggtttgatga taaagaatgt ttgttccata ctcgtctcct ttgtcagctt
     4681 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga agagagaatg
     4741 agagaaccct cgggttctct cattctctct tattctactg tttcttccac agtttcaacg
     4801 gcagtatcca caactacttc tgttgtttct ttatttcctt cttcctctac tggaggatta
     4861 aggtattctt cttcgttgac agcatgtggt tcaaggttac ggtaacgggc cataccagta
     4921 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
     4981 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
     5041 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
     5101 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
     5161 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
     5221 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
     5281 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
     5341 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
     5401 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
     5461 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttgtcct
     5521 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
     5581 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
     5641 attgtaagct gtgtaccagg ttccccgata gattgggcag cgattgtacc aactgcttca
     5701 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
     5761 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
     5821 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
     5881 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
     5941 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
     6001 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
     6061 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
     6121 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
     6181 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
     6241 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg attagcaatc
     6301 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
     6361 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgttcgac acgtttgtgt
     6421 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
     6481 aatcctgcaa gagttgagtg gtggtaaccg aggttcttca tgcggtcaag tagggcagaa
     6541 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
     6601 ttgaatggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
     6661 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
     6721 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
     6781 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
     6841 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
     6901 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
     6961 atgtcctgag atggagtaac taccggtttc ccatctttcg ggttcaagat gtgctcagca
     7021 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
     7081 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
     7141 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
     7201 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
     7261 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
     7321 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
     7381 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
     7441 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
     7501 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
     7561 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
     7621 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
     7681 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
     7741 gggataaccg gaaggatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
     7801 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agcagttttc
     7861 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
     7921 atggcttccg cacccatctt agcaacaaat gaaccataac catattcacg caagcgctct
     7981 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
     8041 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
     8101 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
     8161 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
     8221 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
     8281 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacgg
     8341 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
     8401 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
     8461 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
     8521 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgggct gctttttcgc
     8581 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
     8641 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
     8701 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
     8761 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
     8821 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
     8881 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
     8941 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
     9001 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
     9061 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
     9121 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
     9181 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
     9241 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
     9301 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
     9361 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
     9421 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
     9481 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
     9541 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
     9601 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
     9661 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
     9721 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
     9781 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
     9841 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
     9901 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
     9961 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    10021 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    10081 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    10141 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    10201 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    10261 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    10321 aggttccatc ttcattcaga cgagagttag cctgagctac agtatattca tcttcttcat
    10381 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    10441 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    10501 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    10561 gcacgtcacg tacttcatat ccggcacggt cacgagtcaa accaccaggt cctaaggctg
    10621 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    10681 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    10741 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    10801 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    10861 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    10921 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    10981 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaataacc ttgaattttt
    11041 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    11101 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    11161 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    11221 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    11281 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagccgtct
    11341 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    11401 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    11461 aaatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    11521 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    11581 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    11641 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    11701 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    11761 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    11821 gtgctgagta gctagcatcg tgaatacgag cttcttctag cgtgtatttt ggttccttga
    11881 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    11941 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    12001 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    12061 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    12121 gccttgtcaa tcaggctttt ctaatcgtca tatggttgta aaccccttat caccgtgtcc
    12181 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcataat cttgaaaaaa
    12241 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    12301 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    12361 ctagattttt caaggggttt cagtaggttt ttggtaaatt ttttcccata gaaaacttgg
    12421 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    12481 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    12541 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    12601 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    12661 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    12721 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    12781 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    12841 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    12901 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tggtatcaac
    12961 gtcatcactt tccagctcaa catcaaagta attattgaaa tcattgaggg tcatagttcc
    13021 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    13081 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    13141 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    13201 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    13261 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    13321 tccaattaca ttgtccttat ccccatcata aactgggata cgagaataat tttgttttaa
    13381 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    13441 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtagcatctc
    13501 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    13561 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    13621 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataatcgg
    13681 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    13741 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    13801 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    13861 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    13921 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    13981 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    14041 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    14101 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    14161 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttacg
    14221 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    14281 aactggaagt tagttttaga agttactatt ttttcttagt acctattcta gccctgctta
    14341 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    14401 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    14461 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    14521 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    14581 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    14641 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    14701 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    14761 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    14821 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    14881 ttagctacgg ttggaacagt ttccttgccc actgtctttg ttttattgtc agcgtagggc
    14941 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    15001 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    15061 gccaatgctt gactaggagc ttcagacgct tgttttttct gactaagctt ggttttagga
    15121 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    15181 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    15241 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    15301 ctggagacag gatagcccat ggatcttgac ccttgcccaa gattccataa cctaccatta
    15361 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    15421 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    15481 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    15541 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaggc tgcactggca
    15601 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    15661 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    15721 cgattttcga aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    15781 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    15841 gcttttagat tttctagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    15901 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    15961 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    16021 tcttggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    16081 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    16141 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    16201 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcgccatgc
    16261 aagcgttctg ccttggcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    16321 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    16381 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcacgc
    16441 atcttgctga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    16501 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    16561 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    16621 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    16681 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    16741 cttgatttca taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    16801 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataaa cgaacttttc
    16861 ttgtattatc atctgtcact tttaaaacct tctcccatct aacaagatcc tttaaaaggt
    16921 aaaaactcac ataaataaag aacatatgac tacttagagt gaataataat tgaaccattt
    16981 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    17041 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    17101 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    17161 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    17221 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    17281 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    17341 gagtatagat agctagacta aacatgagac cagcacttgg accgccaata ccagctgttg
    17401 aaaagctaat tgggacattg ctgattacct ctgtacggtc aatcaagccg attccaattc
    17461 catttttgcc attttccaag gtgatgattt ttccttctgc agacttggtt tgcccatcct
    17521 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    17581 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    17641 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    17701 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    17761 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    17821 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtggcat
    17881 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    17941 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    18001 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    18061 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    18121 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggccgg
    18181 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaacta
    18241 gcttcatatt gcaaatccgc cgcattcctc aacccccgta ctaggaaagt agcccccagt
    18301 ctttttgcaa catcgaccac caatttatca tgagaagcca cgacttcaac attttccaaa
    18361 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    18421 tggggattaa aaaaaatacc cacataaagc ttatcaaaga gtctgctcgc ccgttcaatg
    18481 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    18541 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    18601 aatctcttct ggaagttcaa cggccttatc cgtctcgcac acaaccataa catcttcaga
    18661 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    18721 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tctctgcatc
    18781 catcttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    18841 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    18901 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtcccc cttcaaagta
    18961 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgtcgtctt
    19021 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    19081 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    19141 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    19201 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    19261 ttgtcaatgg gaatagacca ttcaacaaag acttgtgcca ttccaattcc aagcggtctt
    19321 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    19381 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    19441 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    19501 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    19561 tacaaatcgc attttcacgt tctttcggtg tcaagtctgg gtagcgttct accaattctt
    19621 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    19681 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    19741 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    19801 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    19861 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    19921 gcaccacttc ataagtagca tcagggattt ggagaacctt gacagatact ggattttcca
    19981 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    20041 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    20101 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    20161 attatacacc tatttccaaa aaaagaaaag agaaaattta aaaaaatcag tgtcactcaa
    20221 aacactgatt tcatagacct tttagtcatt gcgaccgaag atacgtagaa tacttaggaa
    20281 aagattgata aaatcaagat agatgctgag agccattgac accacccagc ctgtcgctac
    20341 acgaccttgt gattgttcat aggcgaggcg aatcttttga ttatcccaag caatcaaccc
    20401 tgaaaaaacc aaaaccatgg ctacgctaat catataatca aagaagccac tagccaagaa
    20461 aatattgact accatagcaa tcagtaaacc aatgagagct gccatcattg ctcgaccaat
    20521 cccactcaag tctttcttgg taaagatacc aactgccgcc atgacaaaga agagaagggc
    20581 gctcgataca aaggcagata aaactgtacc cggagtatag aaagccacca caaaactaag
    20641 ggtaaagccg tttaaaacgg agtaaagtaa aaatactgga agagcagctg gactatttct
    20701 tgaagccatg ctactggcaa cgaaaaccaa agccaactcc gaaaaagtag caatggtcaa
    20761 ccagagacgc ccctgcatca acaagtaaac caactgagac tgaaagaccg tcaacataag
    20821 gcctgatacc aaagcagata gtccgattcc cagaccaaca aaggcataaa ccttagcgta
    20881 aaattgattg agacctgcac ggtcatgtat aatagtgtga ttcatccttt tctccttttc
    20941 tgtgaacatc tttccttgat tataacaaaa aaagttaaaa ttagcttaaa tggaagatta
    21001 aaataccggc tgcaactgca acattcaaac tctcggcctg ccccttcatg ctaatatgga
    21061 ccaactggtc tgcactttca gccataaggg gactaattcc ttgaccctca tttcccataa
    21121 ctagtacaaa attttctata gaaggcagtt ctctgtaatc aacagaatct ttagataggg
    21181 ttgttgctag cactgggata gctacctttt tagtttcgtc aagaagcgct tgactagtca
    21241 tccggtaaat gggcagatgg aaatgactac cttgcatgga acgtagggtt ttgagactgt
    21301 agatgtctgc cgacttatct gaaacaatca ctcctgtaaa acctgctgca tccgcagttc
    21361 gaatgatagt tcctacatta ccaggatctt gcacatcttc caaaaacaag aacttgccct
    21421 gactcaaatc agcttgtcct acttcttctt tttgaaccac ggcaacaatt ccctgtggag
    21481 tctgagaatc cgccaaatct agcaaaatat cctctgacac ccagacagtt tgcgaaaaag
    21541 tagctaactg atctcgataa ttttctaggg taaagatttt ctcaatcgtc actccagctt
    21601 gaacagcttc ttcaaacaag tgccagcctt caattaaata ggcagacttg cggtattttt
    21661 tttggtgtaa tttcttggca ttttttacca cagaattggc ttttgaggtt ataatagtca
    21721 tagaaatatt ataacacaat caaaggggtt tggtatgcaa aaggttagaa tgattgccca
    21781 aggtagggta cagggagtcg gctttcgttg gggtgtttac agcttggcac ttgaaattgg
    21841 tggcatcaca ggtcgagtat ggaataacga cgatggcaca gtggaaatct tagcccaagc
    21901 agactcatct gctatcatgg caaaatttat ccaagaaatc cgaaaaggac cgacaccttt
    21961 ttcaaaagta agctacttag atgtcaaact aagcaacttt cctccctact ctgattttaa
    22021 aatcgcaaat taggtctcca gaactattgt atattttgta aaaaaacagt agaatagaaa
    22081 ggtataattt ttaaagaagg aataaaaaca gtgaaatcta ttaaacgttt tgcactctca
    22141 gctatgggag tggctatgtt gcttgtcttg actggctgtg tcaatgtcga taaaaccaca
    22201 ggtcagccaa caggatttat ttggaatacg atcggagcgc ctatggctga agccatcaag
    22261 tacttcgcta ctgataaagg tctaggcttt ggtgtcgcta tcattatcgt aaccattatc
    22321 gtacgcttga ttatcttacc acttggtatc taccaatcat ggaaggcaac gcttcactct
    22381 gaaaagatga acgccctcaa gcacgtcctt gagccacacc aaacgcgtct caaagaagcg
    22441 actactcaag aagaaaaact cgaagcccaa caagctctct ttgctgctca aaaagagcac
    22501 ggtatcagca tgtttggcgg tgtaggatgt ttccctatcc tccttcaaat gcctttcttc
    22561 tctgctatct actttgctgc ccaacatact gaaggggttg ctcaagcaag ctacctaggc
    22621 attcctctag gttctccaag tatgattttg gttgcctgtg ctggtgtcct ttactatctt
    22681 caatcgctcc tttcacttca cggagtagaa gatgaaatgc aaagagaaca aatcaagaaa
    22741 atgatttaca tgagcccact catgatcgtc gtcttctccc tcttctcacc agctagtgtc
    22801 acactttact gggttgtcgg tggtttcatg atgattctcc aacagtttat cgtcaactat
    22861 atcgttcgtc caaaacttcg caaaaaagtc cgtgaagaac tagccaagaa cccaccaaaa
    22921 gcaagtgctt tctctaaacc aagtggacga aaagacgtta cccctgaaca accaactgct
    22981 atcacaagca agaaaaaaca caaaaatcgc aacgctggaa aacaacgttc gagataagaa
    23041 gaaaaaggct tagctgattt gctaagtctt tttgcaaatc aaaagcccga tgtttccatc
    23101 aggcttcttt tctatccatg tacacgtttc atataatctt gataactttc ggtatccatg
    23161 agttttttag cgttcttgac gcgatctgct gttggtggtt tgactccttc gagggaatat
    23221 ggaattccaa gttcacgcca cttgaactca cccatggtgt gataaggtag aatttcaaac
    23281 ttatcaacat ttttgagggt cttgacgaac ttaccaagtt caatcaagtc atcatctctg
    23341 tctgtcaatc ctggaactag cacgtggcga atccagacag gttttccaat atctgataga
    23401 tactgggcac aagccaagat atttttatta gtttggctag tgacaatctt gtgctgttct
    23461 tcgttgattt ccttgatatc caaaagaacc aagtcagtga cagccatgag tttgtcaaac
    23521 ttctcaaggt aacgtggttt attacggaaa ggaagagcac aggtatccaa ggtacagtgg
    23581 attccttgtt ccttagcctt ggtgaagaga gcaatcagga aatcaatctg caagagagct
    23641 tctcctccac tgactgtaat cccaccctta tttccccaga aaccacggta gcgcaaggcc
    23701 tctgtcaaga catcatctac cgtccgttca cgtgacttat tggactccat agcccaagtg
    23761 tctgggttgt ggcaatactg gcaacgcatg tgacagccct gcaaaaagac aataaagcga
    23821 ataccaggcc catctactga cccaaagctt tctgtcgaat gcaccattcc tgtcacttgt
    23881 ccataatcaa ttgtttcttc agacatatcg ttaccttcct tgaaaacgtt ttatagtttt
    23941 attatatcac gacttgaagg aaaaacaaga tttttgccta ttttttagaa agcaatctgt
    24001 ttttcaattt cattttcaat ctattatcag attattcttc aaaatcgaag ccatataagg
    24061 ttgcaaaata gtcctcaggg cgctctgcac ggcggatttg acgggcttta ccttcttcgg
    24121 tatagaggat ttccgcagaa cgtaatttgg cattatactg gtagcccatt gaaaatccgt
    24181 gggcacctgt atcatgaatt accagcaaat caccgatttc tgtatgaggc agttcgcgat
    24241 tgactgcaaa tttatcattg ttttcacaga gtgaaccaac cacatctacc gcttcagctg
    24301 gtccatctgg atgggtcacg ttgctaatat gatggtaagc tccgtacata gctggacgca
    24361 tgaggttgac tgctgaggca tccacaccta gataggtacg gtaggtttcc ttcttatgag
    24421 tcactcttgt gactagagca ccgtgaggtg ccagcataaa acgacccaat tcggtgaaaa
    24481 tcttgacctg accaagacct gctgacgtaa gaacttcttc atacacctta cgaactccct
    24541 caccaatcaa ggcgatatcg ttcggctcct ggtctggacg ataattaaca ccaataccgc
    24601 cagaaagatt gataaagtct agccaaatgc ccaacttttc cttgatttca acagccagtt
    24661 caaagagctg acgagccaac tctggataat agagatgggt cacggtattg gacgctagga
    24721 aggagtgaat cccaaaagtc ttggctcctt tttccttcaa gatagcaaag gcttcaaaga
    24781 gctggtcctt ggtcatgcca aacttagcct ccccaggatt gtccataatg tctgtcccca
    24841 gttcaaaaac gcctccagga ttataacgac aagagatgat ttctggaata cctgctgctc
    24901 tctccagatg ttcaatatct tcaaaggcat ccaagttaat ggtcgcaccc aattcacgtg
    24961 cataggcgta ttccttgtct ggcgtgttgt tggaagagaa cataatctca gaacccagaa
    25021 agtccagttt atggctcatc aaaagctcta cataactaga gcagtccaca ccacaacctt
    25081 cttcttggag aattttcaaa atagctggag ttggagtagc cttaactgca aaatattcct
    25141 taaagccctt gttccacgaa aaagcttggt tgacggctct tgccttctca cgaatcccct
    25201 tctcatcata caagtgaaag ggagtcggga actcggcaac aatcgcttct aactcttctc
    25261 tattgataaa tggtgttttc ataagcttcc ttctattctg tttgcaaaga aaggctggga
    25321 caatcgttcc aacctttagt tctatctctt atttatcttc gtcaaagata ttgccaacct
    25381 caacatcgat ggcttggttc ttgacatcaa tattagttac cttcaagagt gacttgtagt
    25441 caaactgctt ttcacgttct tcttgggcat tgtccgcaaa gaccgctaca cctgccagtt
    25501 ctgagtcgaa ctcgcgcaag agactaatca taccgttgac cgttccgcca cctttcaaga
    25561 agtcatccac aatcaagaca cggctgcctg ccttaagact acgttttgaa aggaacattt
    25621 tctcgatacg gtcaccactt gaacctgaaa catagttgac gctaacagtt gaaccttcgg
    25681 taattttcag gtcacggcgc acaatgacaa aagagacatt gaggacattg gcaactgcat
    25741 ttgcaagtgg cacaccctta gttgctacgg tcataaccgc gtcaattttt tggtccataa
    25801 agcttttggc aataatacga ccaatatttt tcaagatggc tggtgtgcta agcaaatcag
    25861 acagatagat ataaccacct ggcaagatac ggtcactttc tgacaacttg gtacgcaagt
    25921 cttcaaccat ttccttagca tcctgactcg aaatagacgg tgtgaagatg acacctccgc
    25981 cagccccagt cactgtctgg atatgaccga tttcaatttc ctcaaaggcg cgtttgataa
    26041 tgacgatatc ttctgagatg gatgatttag cagactcata cttttcagca aaagtattga
    26101 gactagttag tttataagga ttattaatca aatagttgga aatgacaacc atccgatcac
    26161 ttcttcttaa tttcatttct atttcctatt ccatttttat tcaaaaaatc aaaaagcaaa
    26221 ctagaaagct ggtcgctggt ggttcaaaac actgttttga gattgtcgat agaactgaca
    26281 aaccctgtaa tatacctgca tatatacata cgacaaggcg atactaccct agtttgaaga
    26341 gattttcgaa gagtattcat ttttgtcttt tacttattat accatattca cataaaaaaa
    26401 cgaacattct tatcctaaaa aat
//
LOCUS       DAVKZI010000030        25211 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKZI010000030 DAVKZI010000000
VERSION     DAVKZI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.031"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(287..2938)
                     /gene="adhE"
                     /locus_tag="VXB18_001447"
                     /gene_synonym="adhC"
     CDS             complement(287..2938)
                     /gene="adhE"
                     /locus_tag="VXB18_001447"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0382632.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(3238..3648)
                     /locus_tag="VXB18_001448"
     CDS             complement(3238..3648)
                     /locus_tag="VXB18_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382633.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(3650..4078)
                     /locus_tag="VXB18_001449"
     CDS             complement(3650..4078)
                     /locus_tag="VXB18_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0382634.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(4125..4424)
                     /gene="yajC"
                     /locus_tag="VXB18_001450"
     CDS             complement(4125..4424)
                     /gene="yajC"
                     /locus_tag="VXB18_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0382635.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(4541..6517)
                     /gene="tkt"
                     /locus_tag="VXB18_001451"
     CDS             complement(4541..6517)
                     /gene="tkt"
                     /locus_tag="VXB18_001451"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0382636.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            complement(6631..7722)
                     /gene="ulaG"
                     /locus_tag="VXB18_001452"
     CDS             complement(6631..7722)
                     /gene="ulaG"
                     /locus_tag="VXB18_001452"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0382637.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(7834..9507)
                     /locus_tag="VXB18_001453"
     CDS             complement(7834..9507)
                     /locus_tag="VXB18_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0382638.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQFLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKSLLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            complement(9686..10390)
                     /locus_tag="VXB18_001454"
     CDS             complement(9686..10390)
                     /locus_tag="VXB18_001454"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0382639.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVTYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(10392..11255)
                     /locus_tag="VXB18_001455"
     CDS             complement(10392..11255)
                     /locus_tag="VXB18_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0382640.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTEN
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(11259..11924)
                     /locus_tag="VXB18_001456"
     CDS             complement(11259..11924)
                     /locus_tag="VXB18_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0382641.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            complement(11941..12426)
                     /locus_tag="VXB18_001457"
     CDS             complement(11941..12426)
                     /locus_tag="VXB18_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0382642.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(12503..12784)
                     /locus_tag="VXB18_001458"
     CDS             complement(12503..12784)
                     /locus_tag="VXB18_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0382643.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(12807..14264)
                     /locus_tag="VXB18_001459"
     CDS             complement(12807..14264)
                     /locus_tag="VXB18_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0382644.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(14395..15018)
                     /locus_tag="VXB18_001460"
     CDS             complement(14395..15018)
                     /locus_tag="VXB18_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0382645.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(15069..16055)
                     /locus_tag="VXB18_001461"
     CDS             complement(15069..16055)
                     /locus_tag="VXB18_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0382646.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(16074..16898)
                     /locus_tag="VXB18_001462"
     CDS             complement(16074..16898)
                     /locus_tag="VXB18_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0382647.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(16873..17244)
                     /gene="rnpA"
                     /locus_tag="VXB18_001463"
     CDS             complement(16873..17244)
                     /gene="rnpA"
                     /locus_tag="VXB18_001463"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0382648.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(17392..18582)
                     /locus_tag="VXB18_001464"
     CDS             complement(17392..18582)
                     /locus_tag="VXB18_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0382649.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSIPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(18633..19586)
                     /locus_tag="VXB18_001465"
     CDS             complement(18633..19586)
                     /locus_tag="VXB18_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0382650.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(19647..20241)
                     /locus_tag="VXB18_001466"
                     /pseudo
     CDS             complement(19647..20241)
                     /locus_tag="VXB18_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(20378..20788)
                     /locus_tag="VXB18_001467"
     CDS             complement(20378..20788)
                     /locus_tag="VXB18_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0382651.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKSEEKPEKKENS"
     gene            complement(20766..21227)
                     /locus_tag="VXB18_001468"
     CDS             complement(20766..21227)
                     /locus_tag="VXB18_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0382652.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            complement(21190..21450)
                     /locus_tag="VXB18_001469"
     CDS             complement(21190..21450)
                     /locus_tag="VXB18_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382653.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(21455..21859)
                     /locus_tag="VXB18_001470"
     CDS             complement(21455..21859)
                     /locus_tag="VXB18_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0382654.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(21852..22118)
                     /locus_tag="VXB18_001471"
     CDS             complement(21852..22118)
                     /locus_tag="VXB18_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGC"
                     /protein_id="HEV0382655.1"
                     /translation="MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAEL
                     YSLEKNEDASLRKLQADGRITEEQAKAYKEYHDKNGGANRKVND"
     gene            complement(22120..22377)
                     /locus_tag="VXB18_001472"
     CDS             complement(22120..22377)
                     /locus_tag="VXB18_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382656.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYQVPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVRMYEIEKSENFTILD"
     gene            complement(22647..23603)
                     /locus_tag="VXB18_001473"
     CDS             complement(22647..23603)
                     /locus_tag="VXB18_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0382657.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGLVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKHDIENGLSVEAGWKKNDTGYWYVHLDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     SWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(23603..23938)
                     /locus_tag="VXB18_001474"
     CDS             complement(23603..23938)
                     /locus_tag="VXB18_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0382658.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            complement(23942..24241)
                     /locus_tag="VXB18_001475"
     CDS             complement(23942..24241)
                     /locus_tag="VXB18_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382659.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(24250..24600)
                     /locus_tag="VXB18_001476"
     CDS             complement(24250..24600)
                     /locus_tag="VXB18_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382660.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            complement(24603..24806)
                     /locus_tag="VXB18_001477"
     CDS             complement(24603..24806)
                     /locus_tag="VXB18_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382661.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(24787..24904)
                     /locus_tag="VXB18_001478"
                     /pseudo
     CDS             complement(24787..24904)
                     /locus_tag="VXB18_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
     gene            complement(24901..>25211)
                     /locus_tag="VXB18_001479"
     CDS             complement(24901..>25211)
                     /locus_tag="VXB18_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0382662.1"
                     /translation="KYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDFIENKKHE
                     EIGLIAQEAETIVPKIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA
                     "
BASE COUNT         7136 a         5530 c         4523 g         8022 t
ORIGIN      
        1 atatttttta tataataaaa tgaaatagga ataggacaaa tcgatcagga cagtcaaatc
       61 gaattctaac aatgttttag aagcagaagt gtactattcc agtttcaatc tattatatat
      121 tttgtttcta ttctagtttt tcaaaaaggg caaaaaggcc tcaatatcat aaaaaggcat
      181 cctatcaggt gttcaaaaac cttgatagga tgccttttat catagaaaaa ttactggatc
      241 tttccctcaa attgagtttt tgtcttgctt ctagactgat aaacaattat ttacggcgtc
      301 ctggtctttc tttgtagcca tagtatgcat cttcgatgat ttcttgcata tggtctacca
      361 ttggaagacg tgggttagct ggtgaacatt ggtcttcata agccaggaag gctaattcac
      421 gagaatgttc tttccattct ttttcgtcaa ttccttggtc tctaaaattc atttggatcc
      481 caatacgttc accgagttcg tagacagctt ttgcgtaaga ttcaacccct tcttctggag
      541 tagaagctgg aagtccaagc atgcgtgcga tatcttggta tttttcatct gcacggtagt
      601 agttgtactt aggccatgtt gctgtcttag ctggacgtgt accgttgtaa cggataacgt
      661 atggaagcaa gatagcattt gtacgaccgt ggattgtgtg gaattgcgca ccaatcttat
      721 gggccattga gtgagaaata cctaggaagg cattggcaaa ggccatacca gcgattgttg
      781 aagcgttatg cattttctca cgtgagtgga agtctgcatt cttaactgag ctttcgagat
      841 tttcaaagac caatttaatg gcttgaagtg ctaaaccatc agtgtagtca ctagccattt
      901 gtgatacgta tgcttctgtc gcgtgagtca atacgtccat accagtatca gcagcaacaa
      961 atcctggaac tgtcaatacc aaagcaggat ctacgattgc cacagttggt gtcaatgagt
     1021 agtcagcgat tgggtattta cggttgtttg ctttatcaga gataacggca aatggtgtta
     1081 cttcagatcc tgtaccagat gtagttggaa tcgcgatgaa tttagtcttc ttaccaagca
     1141 atgggaactt gaaggcacgt ttacggatat ccatgaattt ttggacaagg tcacggaagt
     1201 ccacttctgg ttgctcgtag aagagccaca ttactttggc agcatccatt ggagacccac
     1261 caccgagtgc gatgatggta tctggtttga aggcacgcat aatctcagta ccacggttta
     1321 cagttgtgat atctggatcc ggttctacat ccgcaaagat ttggtaaaca accttattgc
     1381 gacgaaggtc cagttgttcg atgatacgat caaggaaacc aagctctacc atggcatggt
     1441 cagtaacgat catgacacgt tcaacgtcac gacatttttg aaggtattga attgaatcac
     1501 gttcaaagta tgtttttgaa ggaagtttca tccattgcat gttatttctc cgtcttccga
     1561 cttttttgat attcaagagg ttaatggcac taacgttatc cccaactgag ttgcgtccgt
     1621 aagaaccaca tccaagtgtc aatgatggca agaaggcatt gtaaacgtcc ccgataccac
     1681 caaaagtaga aggtgagtta cagataacac gaatagcttt aacagcttta ccaaattctt
     1741 tagtcaattc ttcgtcagct gtgtggatag ctgctgagtg tccaagaccg ttaaattcaa
     1801 ccatttgacg agccttagta ataccatctt cacggctttc agatttcaaa actgcaataa
     1861 ctggtgacaa tttttcacga gtcaatggct cattttcgcc aacttcttta cattctgcag
     1921 caagaatgtt tgttccttct ggaactgtaa atcctgcttg ttctgcaatc caagttgctg
     1981 gtttaccaac gatgtcagcg ttcaattttg caccagcaca gtttttgctg tttgctttga
     2041 cgccgaagca gaactcttca agaagagctt tttctttttt gtttacaaag taagtgtggt
     2101 aagatttgaa ctctgctaca aattcatcgt aaatttcttt atcaatgata actgcttgtt
     2161 cagatgcaca gaccataccg ttatcaaatg atttagacat gacgatatcg tgtgctgctt
     2221 gacgaatgtt tgctgatttt tcaacataag ctggaacgtt tccggcacct accccaagag
     2281 ctggtttacc acatgagtat gcggctttaa ccatggcatt accacctgtt gcaaggattg
     2341 ttgcaatacc ttcgtggttc ataagggcac tagttgcttc catagatggt tgagtgatcc
     2401 actgtacaca gttttcagga gcaccagctg cgatagctgc atcgcggacg atacgagctg
     2461 catgagctga tgattcttga gctgatggat ggaaggcaaa gacgattgga ttacgtgtct
     2521 tcaatgaaat caatgatttg aagatcgctg ttgatgttgg gtttgttgtt ggagtgatac
     2581 cacaaacaac accaactggt tcagcaatca gggtcaatcc tgttacatca tcttcttcga
     2641 taacgccaac tgtcttagtg tgacgcatgt tgtttaccac gtgttcacaa gcaaacaagt
     2701 tcttagttgc tttatcttca aatacaccac gtcctgtttc ttcaaaggca tgtaaagcca
     2761 attctccgtg ggcatccaaa gctgctactg atgctttggc aacgatgtag tcaacttgtt
     2821 cttgatccaa tttacgcatt tcttcaaggg caactagagc tttttgaacc aactcatcta
     2881 cgtgtttttc agcaacgagt ttcttttcct ctggtgtcac agttttttta tcagccatat
     2941 tttcctccat agctttcaag gaacgatatc ctttgttaat tttttcacaa gtttattata
     3001 acgcattatt tcaactttgt aaacagtttc ataaacattt cacaaagaat ttttaaactc
     3061 ttgtgaaact tttctcattt tcttttctta tcaagtttta tctttgaagt ttgtgaaatt
     3121 tatttcaaat attttttatt tcacaaactt gcttggaaga gggatttgga aagaaaggga
     3181 tttacaggta agcgcttacc ttgtgattct aataatacct cctttgataa ggaggcttta
     3241 tttttgttga aaaacgcctt gtttaaaagt tccttcataa acgacttctt gttctgttgt
     3301 tagtttccct tttccttcag cctgaccatt tacaaaatca ccttcgtagg tccagccttc
     3361 tttagattga aaggtacctt ttccgttgaa ggctccattg ttgaagccac ctgtatattg
     3421 gtctccattt tggaaggtaa tggtaccttg gccattcatt ttaccacgga caagactgcc
     3481 atcataaaca atcgttccat tatcgagttt taagacacct tttcctggaa tatttagaaa
     3541 aaagacgagt acagcacaga aaacaatggt aactactgcc aaaagctcta aacgtggacg
     3601 agtcagatag acacgatact tttcgtaaaa attcgtaaga ttttccacct taactctcct
     3661 tttctaaacg ttctaaccaa gcttgacagc cctcttgaac acgtcgatag gtttcttcaa
     3721 aatctcctgt ataccaaggg tctggaacac tttcagatga aaatgagtaa atcttatctt
     3781 gacagtctac tggacacatc tgacataagt cagaaatatt tgaagcgtcc attccgataa
     3841 tataatcaaa ggcttcaaaa tcttccttac taatctgaag cgatgtcttg ttcttgtcat
     3901 aaggaatctc atactcttga aaaattccct gagtcccctt atgaatcgga ttgccatgtt
     3961 cccaagagga agttgctcga ctttggattt cgtagttatc tgtcattgat ttcataacaa
     4021 actcggccat agggctacgg caaatatttc ccagacagac aaagactaat tttttcatcc
     4081 catttccttt cttttataga aaaacgggag ttcgtgatcc cgtcttattt ttcaattgcg
     4141 ccttctagtg aagctgtttc tttcagcggt aatactgtct tgatagcagc tagttcaaaa
     4201 gtcaagtaaa ctccatctac gtcaagaact attgttccct tctccgtatc tacttcatcg
     4261 actgttccat aaagtccacc gattgtaatc acttcatagc ctttttgtag tttatttaag
     4321 ctttccatac gcttttgagc ttgtttcttt tgagaacgtt gcataaagaa catcaaggcc
     4381 atcataccta caagcatgat taaaaaagta atatttggat tcattgtttt ctcctttgtc
     4441 ttttacatag gactactata tcaaatttca gctactttta caagattgta ccttactttt
     4501 ctggtaagaa aaaccagagc ttacgccctg atttttagga ttatttcaag tttcgaacaa
     4561 tttttacaag attttctaca gtaaagccat attctgccaa tacttttggt gctggggcag
     4621 aggctccgaa ggtatcaata cctagaacgg caccatcgag accaacatat ttgtaccagt
     4681 tttgacttgc acccatttcg actgcaacac gacggcggac tgcatttgga agaatctctt
     4741 ccttgtaagc tgcatcttgt ttatcaaaga catctgtaga tggcatgctg actacgcgga
     4801 ttttttcgcc ttgactagcc aattctttag cagctgagac agcaagatta acctctgaac
     4861 ctgtcgcaat caagatggta tcaaagtcgg ctgcattttc atatacaaca taagcacctt
     4921 tagcaacctt gtcgaagtct gttccatctt caacagtcaa gttttgacgt gtcaagacaa
     4981 gggcagttgg tgttttctca cttgtcactg caaggtacca agctgcttgc gtttcacgcg
     5041 catctgctgg acggaaaaca tttagatttg gcatagcacg aagacctgct aaatgctcaa
     5101 ctggttcgtg agtcggacca tcttccccaa ctgcgattga atcatgggta aagacataag
     5161 tcacaggaag tccttgtaag gctgacaagc ggacagctgc cttcacatag tcagagaaga
     5221 cgaagaaagt tccaccgtat acacgaagtc caccatgaag ggccatcccg ttcaagattg
     5281 ttcccattgc aaattcacga acaccaaact gaatgttacg attcaagcga ttggcatcgt
     5341 cttgaagtcc atccgtcttg atataagtca tgtttgagtg agcaaggtca gctgatccac
     5401 ctagaaaggt tggtaattta gctgccacaa cattcaaggc atcttgactt gaattacgag
     5461 ttgcttgaga aaaaccattt tctaaagctg ggaagtctgc tggagtcact tcgactggat
     5521 cacgtccgtc gatgatggct tctacttctg cagccagttc tggatgagct tctttataat
     5581 ctgcaactaa tttagtccaa gcttgataag ctgatgcgcc acggtctgca acatgttctt
     5641 tgaaatcagc atatacttgt tctggaattt caaatggttc gtagtcccaa ccgagggctt
     5701 gacgagttga tgcagtttca tctgctccaa gaggggcgcc gtgtacagca ttagttcctt
     5761 gtttgtttgg agaaccgtat ccaataaccg tcttcacttc aatcaaagat ggcttgcctg
     5821 aagcttttgc tgtttcgata gcagcatgga tggcttccaa gtctgttcca ttttcaacca
     5881 aggcagtatg ccaaccgtag gcattgtaac ggtcacgaac actttctgta aaggaatcct
     5941 ttgtctcacc atccaagttg atatcatttg aatcataaag aacaaccaac ttatcaagtt
     6001 tttgcaaacc tgcgtatgaa gctgcctcgc ttgagacacc ttccatcaag tctccgtctc
     6061 cacagataac gtaagtatag tggtcaaaga tattgtagcc ttcacggtta tatttggctg
     6121 ccaagaaacg ttctgcttgg gcaaaaccag tagcagttga aatcccttgc cctagaggac
     6181 ctgtcgtagc atcaatccct gccgtatgac caaattctgg gtgacctggt gtttttgaac
     6241 cccattgacg gaaactctta atctcatcca tgctgacatc ttcaaaacca gaaaggtgaa
     6301 gaagagcata aaggagcatt gaaccatgac ctgctgaaag aataaagcgg tcgcggttaa
     6361 tccagtttgg ttgagctgga ttgatatgaa gttgttttgt aaagaggctg taagccatcg
     6421 gagccgctcc cataaccaca cctggatgac ctgagttggc tttattaatg gcgtcaatac
     6481 ctagaaaacg aattgcatta acagatagat ttgacataga atttcctttc tatttgaggt
     6541 gattattgaa tcacacattc tattttacta ttatatgaaa attatccgta tcatgcaaca
     6601 tacggataac ctccaaagaa tatttttata ttatagcaaa gctttaaatt gaatgttaga
     6661 gtcttgttca aaacaatcat caaaaccacg tggatgatgg tattctacta agtgttgatc
     6721 ttgaggataa gtgtacttac cgccaacttc ccagataaat ggatggaaat cgtattgcaa
     6781 gcgatctttt cgcattttcc aaagttctag aatctcatta gtagaagcca tgaagttaga
     6841 ccagatatca tagtgaactg ggataataac tttggtacgc agattttctg ccatacgaag
     6901 aaggtcgata gatgtcattt tgtcttggat acctaccgga ttttcaccat agttattcaa
     6961 agcaacatca attttaaagt ctttaccatg ttttgcaaaa tagtttgaga agtgagaatc
     7021 tgcaccatga tagatggttc cacctggtgt ttcaaagata tagttaacag ccttttgagc
     7081 catttcttca tctgtaacag ccaatccagc aagttcaccg cctgtctcat cagcaccgtt
     7141 cactgggaga gttaccaagc aagtacggtc aaatgattct actgcatgaa tcttcatatc
     7201 ttttaattcg atagtgtcac ctggtttaac aacgatgata cgttcttttg gaacacccca
     7261 tccttcccag attcgtccac agtggtaagg accgataaac ttaacatgct ctaacttagg
     7321 attgttgaga attgctgcag ctgtgtatgg gtcgatatga tcactgtgga agtgtgaaac
     7381 taagtaatag tctagttcgt tgatagcaaa tggatcgata accattggct gaacacgcaa
     7441 gtttggttgc aacttacgaa cacctgccat atttgccatt tggtgcccac gaaccatatc
     7501 tttcactttt ttggttgatt ttccacggtt tgaccaaagg tccatgacaa cgttagcacc
     7561 agctggtgtc ttaatccaag taccacagtt gcctagccac cacatggcaa aattgccttc
     7621 aggtacgact tcttcttcga tttcttcgtt caaccatgtt ccccactctg ggaaagtggc
     7681 taaaatccat gactctcttg taatttcttt gacgtttggc atatgttgcc tcctttggat
     7741 ataattgtta tctttgagat tagtatacca cccttcaaaa cactaaaaaa gaccaagaaa
     7801 aacacaggtt tgtgttcatc attggactgt ccttcaaata tcttccaaaa aagcttgaac
     7861 tactatttct tgatttataa gtgtttgaac ctcttcttgg aacttactag ccaacttgct
     7921 gtctacaata taagacgaaa taagactaga aagattttca ctgaaacttt tgctctcatt
     7981 acgaaatata ttgtgtttaa gatagtctag cattttcaaa atatcttctg cttcaaggat
     8041 aggattaacc cttaaaatcg gaaatctgct atccaaatca tcattagtag taatcactac
     8101 atcaacttgt gcaatatctt ccacactctt aaattgttct gttgtaaata cagtgtcaat
     8161 ttgctcattt ggaaaataaa gtttgcattg tttcagcaaa agtctcgaaa ccgcaacacc
     8221 ttcatcacaa acgagataaa cttttttcat atttttttga gacgatggtg tatactttaa
     8281 aaatcctcca atatgaatcg tcaaataggc aatatcatcg tctgttagcc gaataaacca
     8341 tgctccttct aaaatttccg cagattttct agtgactaaa aataattctc catacttgga
     8401 tcgaatttgt tttgttagag gatttttaga aaaaataccg taagtctttc taaataacaa
     8461 ggatttacag tggatcatca aatttcgtaa caaatcatcc ttgttctcaa tctccattcg
     8521 gatttgtgat tcaaaatacc agataaattc ttctaaagca agttttaatt gccgaaaatc
     8581 atcactttct gcatgaatat ccaaatcttt acgataggag aggaggagaa cagctacaag
     8641 agaaacttca agtcctgaca aagaaatttc aaacttttga aacaaccgtt ctcctaattt
     8701 cttagacacc tgatactcta ttctttttct tatcaaagaa aattctttct ctatatcctg
     8761 atgtctttct tgatactgtt caacattatg acagcttaac agcaaataag gtagaaactg
     8821 caacataaaa gttatttcat gatggtttat tttcttccct aaatcttgtt caactaaagg
     8881 aacctgttcc ttaaaaaatt ggttcatttc aacagaaagc aaacactcat catctaacct
     8941 ctctttcatc ttatcttcta aaatagatac aaaagtggca ttttcttcca taaaaatatg
     9001 atatagaagc gattgaagat actgaatttt attaagaggg tgggcatgaa ggtggtatcc
     9061 ctgtgacttg ctcacttgca aggtcacctg atattgttcc aaagttagtt gataacgaat
     9121 gctattcaaa tcattgagaa cagtattcct agatacctct gttaactcta tcaatttttc
     9181 aatcgtaata cgttctttag aaatacctat ccatagtaac attatcatca tacgttcatg
     9241 cgcactcatg atataatcgt acgaatctac ttccgataat agtttacaac aagcatctct
     9301 ctgctcttcc gttaagtgaa taccaattcg tggaatacta atgatgtgaa gcgcctcgtc
     9361 acccagagca gcattgattt tgtcaatgtg ataataaatt ttccttcttg actctttcaa
     9421 atctttcgaa atcgccataa tcgttttgga cgtttcttga tccatcaaat attgaagcaa
     9481 atcacaactt gccttatcca gtaccatatt aaaaaatccc ccaaatctat tgatatcaca
     9541 gcaattcttt ttattttacc atatatatat caagcgctat ttctaaaaaa tcttttaaaa
     9601 ttacttcaac tccaacttta ctctcaataa aaatcaaatg taaaaagagg agctaaattt
     9661 atctttttct cctccttcat cgttcttact tttgaccata ataagcattt ggtccatgtt
     9721 tacgttggta gtgtttttct agtatgtact ggggagcagg tccaactctt ggattgattt
     9781 gttctgtaaa gcgattcatc tttgatactt cctctagtac gacagagtga taaacagcat
     9841 tctctggatt tttgccccag gtgaatggac cgtgattgcg tacaacaatt cctggtactt
     9901 caaccgggtt aagtccgcga tgttcaaatt cttctacgat aaccaggcca gtatcttttt
     9961 cataggtcac ttctacttcg tccttggtca aactacgggc gcaagggatt gaaccgtaga
    10021 aataatctgc atgggttgtt ccgtagaaag gaatatcacg acctgcctga gcccaaccaa
    10081 cagcttctgt cgaatgggtg tgaaccacac taccaatttc tgaccaagcc ttatataatt
    10141 gcacatgagt tgggaggtcg gaagatggtc ttaaatcccc ttctaggatc ttaccatcta
    10201 gatcagtcac taccatgttt tcaggtgtca attcgtcata atccacgcct gatggtttga
    10261 taacaatgac accgagttcg cgattgactt cagatacatt cccccaggta aatttgacaa
    10321 gtccatgttt tggcaatgat tgattggcat cacaaactcg tttacgcata gcattgatta
    10381 cttgattcat cttacatcaa acctgctttc ttaatgagtg gatagagaaa agcttgcgcc
    10441 tcttgaatgg ctgcgcgtgt ttcttctact gtttcacaat tttcagacca catttcgatt
    10501 aggaaaggtc cattataatt ggtttccttt aaaatatcga aagcttcttc ccatttgaca
    10561 caaccttgcc cgaaaggtac atctcggaac tggccctttg aattttctgt cactgcataa
    10621 gtatccttga gatggagagc tgcgatggca tgatgaccaa gataaaactc actatagata
    10681 tcattatgcc atgcagacac attaccaata tctggatata caaagaggaa gggagagtca
    10741 atctcttttt ctatagccaa atatttttcg atgctactga tgaaaggatc atccataatt
    10801 tcaatagcaa gtaccacctg agcttcttca gcccagtcac aggcttttct caaatttttg
    10861 ataaaacgtt ggcgtgtctg gggtgacttt tcctcatagt aaacatcgta accagctaat
    10921 tgaatcgtac gaactcccaa gtcttgagct aattcgatac attttttcat gagttctaga
    10981 gatttttcct ctagaactga atcttttgat cccaatgggt agcgacgatg gcctgaaaaa
    11041 cagatagaag gaatacgaac accagtttca tagatttctt tgacaacttc caagcgttct
    11101 tccttactcc agtcaagtct tgctaaacgc tcgtcacgtt cgtcaataga catctcgata
    11161 aaatcaaagc ctaactcctt ggcaaaattt aaacgttcta gccaagtaaa gtgtgttggg
    11221 gttgcctttt cataaattcc aattggacgt accatgattt acccccaaat tcgtttgatt
    11281 tcatccttga aggcacgcgc tgctcctgct ggatccacag cctctgtaat tccacgacct
    11341 gcgataaagg taaagacatc aacaccttca aagagtttga gagtatctac atctagacca
    11401 cctgttacag atacacggaa gcccatgtca atgagttttt taaccttatt aaggtctttt
    11461 tcaccccaag tttcaccagc aagaagagca tcacgagatt ggtgataaat agcttgtgag
    11521 atacctgcat ctagccaaag ctgagcttgt tcaaaagtcc aatcgccata aagctcgatc
    11581 tggatttcgc ctcgttctcc tcgttcagtc ttgatagcct ttagagctgc ttccatagta
    11641 gggatggttg cacaacagat acaagtcatc cagtctgctc cacgaaccgc attattttta
    11701 gcaactgttc caccagcatc agcacatttt gtgtctgcca caataatctt atctgggaaa
    11761 aggctacgca agacttcagc cagttcactt ccaacttgaa gcaagcaaac agttccagct
    11821 tcgataatat ctacttcctg accaacagaa acagctgctt taatcgctcc ttgcaagtct
    11881 gaatggtcta atgcaacttg taaattaggt attctttttg tcatttcttt attcctcttt
    11941 ctaactttcc aaatccaatc cttcgagata agggctatcc ttagattctt caatcatagc
    12001 caagacatct tctttagtct ggcaagcctg taaacgtgca atagaatctt ctaattcaaa
    12061 cagggcaata atttgtggaa tggctacact tgtgtgaatt tttgaacttg ttgctgctag
    12121 tgccaacaaa acagatacct ctttcccatc tgaaaataca acaggatttt gtaaggtaat
    12181 taatgaaaag gcatcacttt gcacaccagc ttcaggtcta gcgtggggca tagccatacc
    12241 tggcatcaag atatagtaag gcccatactc ttcagtcgat tcaatgatag catcgtaata
    12301 ctctggcaaa attgccccac tttcaatcaa gggatctact gctaccttga ctgcttcttt
    12361 ccaatcgtta gcctctaaac ctagtcggat cgagtcgttg tcaattaaag cttgttttaa
    12421 attcatatct gcctccttta tttaaagagg gagaaggaca gaaacgataa ctctcagttt
    12481 ctgtccagcc ccctccaacc ttttactgta gtgcttgact gagtttttcg gtgatttctt
    12541 tatcatccat caagttatca agcccaatta acttcccatt agttcgccct tccaattctt
    12601 gaatcaaatg aagagaagcg attacgatgt catatcctac tgctaaacct ttagcttcac
    12661 cgacactgca tgaattgact gtaaaatctg tttgattaag cttacggaga gcattttcaa
    12721 ccttcatctt gataaccatt gatgaaccca ttccatttcc gcacgctgct aatactttaa
    12781 ccattttatt tctccttttc tagatactaa gcttcttctt gaacttcacc gttgtaatat
    12841 ttctctttat cttttgcttt ggcaaattga agttgaggaa taacaagcaa gaagagacac
    12901 acaagtacat aaccaacaat accaaggtat ttgaagatat atccaaatcc aagccatggg
    12961 aattcaaagt cgatatttcc atggtagcca ccataagatg ccaaatcgag aagggccaca
    13021 caaagagctc ctagagcaac ttgaaggaca cctgatataa aggaaaggat aacagccgct
    13081 ttccatccgc cgcgtttatc agcgtagacc gcaatggctg cattgtcaaa gaacactggt
    13141 acaaatcctg taataataag aatcggattt ttaaagacga tgagcaaaac aattgtaatc
    13201 aattgaccaa tcaaaccaaa gataaatcct gacaggacag catttggaga accaaatcca
    13261 taagaagctg caacgtcaac cgctgggaat gaacctggca acaatttgtt tgaaatacct
    13321 tggaaggcgt ttgtcaactc agatacgaac attcggacac cttgcatcaa aacgaacaag
    13381 taaactgaga aggtaaaggc tgtttggata atgtacataa agaaatcttg tttagcagga
    13441 ttgaatagag ttcctgaagt gatgacttct ttattagaca taatgtctgg acccaagatt
    13501 aaaagaatgg ctccgaagaa tacgagcatc aaggtagcag atgcaacaac tgtatcgtgg
    13561 aagattgaga ggaacttagg taatttaaga ttgtctaaac tttcttcttt cttaccaaag
    13621 cgtcctgcta ctttatctac aaaccagatt gcaaattgct gttggtgacc aatcgcaaat
    13681 ccgccaccac cagtcaagcg ttgagttgcc tcaacagtca tatttgaact aactgcccag
    13741 taaagtccac agatgatacc aatcgctgct gtaccgtaag cattgcgcaa ttgtggtact
    13801 aagaatagaa ccataagaga tactgttgca gcttgttgta ccatgatgtg accagtaata
    13861 aagagggttc ttaccttcgt aatctttcga agagctacga gcaagatatt tattccaaaa
    13921 ccaatcaata gagctgtagt tgcagttcca acaaaatctg gaaactctgc tgcaattttg
    13981 ttgtttgctg cagcaagtcc aaagtaaggg tcgataaccg ctgcaccaat ttggaatttg
    14041 tagttaagag ctgctaagat tggacgaaag gttgtaacca aaccaccagc acccacgtta
    14101 agcaacatat accctactgt tgctttaaca aaccctgaaa aaacgtcatg ggcaggtttt
    14161 ttcaaaagtg catatcctat caacaccaat aaacctacga aaaatgcggg attctgcaaa
    14221 atattgctag aaaaccaatt tagaacactt gaaacgactt ccataattgt tctccttttg
    14281 aattgttttt gtaagtttat tatataatgc gaaagcgcaa acaaaaagac caagaattac
    14341 acagcggact gttcactctt ggactgtatg atttatgatg ttttacaaat tatcttattt
    14401 tctcgtagct agataatagg gaagaatttt agaataagac ttcaataagc cttctacgat
    14461 ttcttcttca gacgaatttt ctgtcatagg aacatctacc ttcactaaaa cttttcgaac
    14521 ttcttgactt ctcaccttct cgcgtaaagt acgacgcttt tcttcattcg cctcccaccg
    14581 ttgactttga ccattagagt aggttagata ataaatccct ttaacggttg gaatgtctaa
    14641 aactttggtc tgcttgccca gtgtttgctc atccttctta cgttcgatga aactgacttc
    14701 caaagaaatt ccaaagtcag tagatgtccc atacaaacgt aaggccatca taggttctgt
    14761 cacttgtccg tctctctgta gataaaccca aaaatgtggt ctcaaacgct gggcctgatt
    14821 catccactga ctagtctgtt ggagttgcca ttctggatgg cttgcttgaa aggctttggc
    14881 cagttctgta aaagcctttc gggcctcttg tcctttgtgg cggaacgcca gcatcttctc
    14941 tcgctctgct cccgctttat caggactacg gtactgcaaa ccagaaaagt ctagatagtc
    15001 tcttatctta ttcaacatca gtttaacctc ctctagctag caaaaaatca ggtcaaccct
    15061 gattttactt attctgtatc tacaacgaca tagcgatttg gctcatcacc ttcagagtaa
    15121 ctggtcacgc catccatacg tgaaataata cggtggataa tcttgcgttc actattcgac
    15181 attggatctg tttgatgact gcgcccttct tctaaaacac gaatcgccaa tttttgcgca
    15241 taggtctgca agacttctgc acggtgttca acataatcat tgacattaat agtgatatag
    15301 aaggttcttg aatagcagtt gtaaagataa ttttgagcca acagttgcaa ggccttcaag
    15361 actttaccat ggtagccgat aatacgacct ggttcgttag tatcaatttg caaattgatg
    15421 ctacgacggt tataatcatt tgaaagtgta gcctcaacat ccatgtcatc aataatcgtt
    15481 tgaacataag cagtcacatc cgtagccacc tgggcaatat cataactttg ctcgaccttc
    15541 aagcccatct ctttcaagtc ttgattttca gtttgatctt gctcagtttc aaggtcatca
    15601 gcgcctgctt cttccctcat cgcttcctcg atttgaagtt catttaaaat ctcaatgtga
    15661 ccagtttctt ctaagatagt gctggcatgt ctttcatgtt ttaagatttc agccttgact
    15721 tcatcagaaa taccttgacc ttcttcctct atttttttaa tagcatcaac cacatgacca
    15781 aggtcaacgg tttcttcact aaccgtcttc acaggctcgt tcaaatcatt gatttttttc
    15841 ggaacgcctt ttactacctg ttgatttgct ttgacaacag tcgtttcact aatcgcttca
    15901 atatccactt gggctggttt tttaccaaat agaccaagaa agcctttttt ctccctagaa
    15961 atgactttga tatgagcctt cattcttgga atatctaatt ctttcaatcc tttctggatt
    16021 gcttcttcaa cagttgaacc tgtaaatact accattacca gattcctcct tatttatttc
    16081 gttttctgag cctttttctt ggcttttctt tttctatttt ccaaatcttt ttgtgcctgt
    16141 actacggcct cgcgctctgc gataatcttg aatggattat tcaagaaata ggtttgcaag
    16201 acttgataag cattagacac tgtccagtat agggcgactc cacctggcgc ataaactgca
    16261 aagataaaaa tcaagactgg aatcccatac atcatcgcag tcgtagcgcc atttcgctca
    16321 gacaaagctt tgttggacaa ccaagtactt aaaaaggtga atactgctgc taaaatcgga
    16381 agaacaaggg ttgtatccac actaccaagg ttaatccata agaaatgacc tgtctttaaa
    16441 aagtcaactc ttgatagggc ttggaacaag gccaaaataa ccggcatctg aatcaaaatc
    16501 ggccaaagag aatctgactg tctgacaccc atttctttaa atactttacg catttcctgc
    16561 tctagtttgg ttctgctttc catatctcga cctggatatt gttctcgaag cgccttaatg
    16621 cgtggctgag cttcctgcat tttcctagaa gccaccattt gcacctgaaa gactggcaag
    16681 aggactgtac gaatcaagac cgtaaagaga ataatcccca ctccgatact aatatcaaac
    16741 gataaaaagc gaatgatttt cgcaaagaag taaaccaatt tactccaaaa atcagccgat
    16801 tcggctgtaa tatcgctagt taccccatta gtcgcacagg ctgtcatgat taacagagac
    16861 agtcctagca aactagtcaa ctttagtttc tttttcactc ccatttcctt cccggtaaat
    16921 ctttgataat tttaatacat ggagtagatt tttctccatc tctgcgtatc ccaaggtttc
    16981 gactcctttt cgagcaatga caacaaagtc gacatcttct accagactcc cttttgcatt
    17041 ctggataata tgccgaatcc gtcgcttaat ttgatttcta gtgacggcat tccccagttt
    17101 tttgctaact gatagaccta ctcgaaaatg gtttttctgg ttttctaatt ggtagaccac
    17161 aaatttgcga ttagcaaaac ttgtcccctc cttgaaaatc gccttaaaat ctttctctct
    17221 ttttacacga aagtttttct tcaaaactaa actccatcta ttaaattact actattatac
    17281 catatttttc aaaaaagcca atcatagcaa ggttttggac aatttcatca gaaaaagaag
    17341 ctggaaaaat aactttccca actccttgta ttgaatattt tttagtttca cttatttttt
    17401 caagcgttca acgtcacggg caatgactaa ttcttcatct gttggaataa ccaagacacg
    17461 gattttagct gcctctgttg agatgtctcc tgtaacgcca aagacattct tttcatcatc
    17521 aacatcacaa ccaaaccacg aaatccctga gattacatca cgacggaaac tctctgcatt
    17581 ttcaccgaca cctgctgtga aaacaatggc atctgctcca tttagcactg caaggtactg
    17641 accgatatgt ttttggatac ggtcaacata catttcataa gccaagctag cctcgtgatt
    17701 cccttctgct acagctgctt ctatatcgcg catatcgcta gaattagcag aaactcccaa
    17761 aagacctgat tcacggttaa gaacacgact gatatcttct ggtgtgttaa aatcctctgt
    17821 atattgcatt aaataaggaa tgatagctgg atcaatatcc cctgtacgcg ttcccatcat
    17881 aataccacca agaggagtga accccataga agtgtctaca gatttgccgg ctttcacagc
    17941 tgtaattgag cctccgttac caatatgaca ggtaattaac ttcaagtctt ctaatggacg
    18001 tcccaagagt tttgcagctt ctcctgctac aaactggtga cttgtaccat gagcaccgta
    18061 tttacgaacc ttgttttctg tgtaatattt tgttggtaga gggtagcgat aagctttctc
    18121 tggtatactt gtgtggaagg aagtatcaaa aacaactaca ctggtaatgt ctggcaacaa
    18181 ttccttgaag gcacgaacac ctgctgcatt ggccgggttg tgtagaggag ccaacaaact
    18241 caactcttca actttttcta aaacatctcc ctcaacaact gttgattctt tgaaatattc
    18301 tccaccagca acaacacgat gtccaacacc tgtaatctcg tcataagcct tgataatatc
    18361 gaaacgaatc aagtcatcca ataaaatttt aacggcttgt atatgatttt caatatccaa
    18421 aatttgttgt tcagaacggc cgtcaaattt tacagttgaa attgaatctt tcaaaccgat
    18481 acgttcaatc aaacctttcg ccaatacttt ttcttctggc attaagtata attgccattt
    18541 caaacttgaa cttcctgcat tgattgcaat tgtttttgtc ataacatgat accccttttt
    18601 aagcgttttc aactattata acaaaatcta ttttatattt cagtaccttg agtccatttt
    18661 tgaaaatttt ctttaaattt cattaaaaca cttgcatctt gcaagctagc aagtggataa
    18721 acaaaaggct ccactgctat ttcacttttc ttctgtagga taaaaatagt cttagattgt
    18781 ttagcattag caaagagatt ttcaggtaaa ctaatcatag caaccagact tgcctcctct
    18841 ttcaaccaga ctttcaacaa atcactttga ggactggtca acaaatcact cggagctaga
    18901 aaaatagcat atccatctga cttaaggtac ttaaaccctt gttccatgag caagtgatga
    18961 gcgtaagtat gttcttggct agaagcaact tgatggcgcg acgcaacggc atcatcagga
    19021 taatagccaa caggcaagtc actgatgacc acatcgcttt ctttgagcat ttgtgggcga
    19081 acggcatctc cttggacaaa gccagcctgc aaaccaatta catctgccat gctagctgcc
    19141 agatcaatca gcaaatcatc cacttccatt cccaagtaat ccaccttttt atcaagcgag
    19201 gtcaagaaag tagcgcctag aattcccatc ccagaaccca tttcgaggat agtaatttcc
    19261 tcctctgtaa acaactcttc cacaataaat accaaaagta aggcaatagc atctggcgta
    19321 aactggtgat tggcctgcaa gggttctgtt tgcccagcct tcatcaagag aaactggtag
    19381 gtcttgagcc attcttcttt gcgtagtgct aaacgcttaa gggcctgatt gttgtctttg
    19441 acctggttta gctcagtttc accatccaga tagatgctat tttgctccac caaggcgtca
    19501 taaaagttgg tcgccaaatc actttggatg acttggacat tctctagtaa atagatataa
    19561 gcttgttcaa ttttttcaaa atccatattc ctatcttatc aaatttccct tcttttttcc
    19621 atccttatag aaaaatcact ccctgactag gcgagtgatt tttgggatac tgttaaaaag
    19681 aattctgagt gattcccttg aaacaggtct tcagcgctat agagaatctg actatgcaca
    19741 gatgaaaaac catgctcaat tagcttgttt tccagttcag ctaaatcaaa tccatgatga
    19801 ttagcttctg tcttggtaaa atcagcaatg atgagtttcc catcttcctt caaatgttga
    19861 tgaaacagtg agagagccgc atccaaatca ggcatatgat gaagaacccg actaacagca
    19921 aggcaatcaa actctttctc caagggattt ttcggtaaat cttgctccaa aaactggata
    19981 ttcttgattg cttgctgctc cactttcaaa cgagcttgct ccaacatttt ctcagaaatg
    20041 tctacaagag tgactgactt agcctgcttg gctaggggtt aggggcaagg ctaatagacc
    20101 cgtgccacca ccgaaatcta aaatttcttt gtctgataga agatcaatct gtttctcggc
    20161 tgcttgacat accaagtttg cgaggaagat atttttaggg gaatcgaaag tttctgcttt
    20221 gtggttaaaa tcatgtttca tatctttaat ttagcacaaa gtatagtaaa ctgaaataag
    20281 atataaacaa atgaattgga gcttaacatc catttccagc aattttctag aaactacagt
    20341 ggactattct ggattcaacg cattatagtt gaattgacta tgaattctct ttcttttcag
    20401 gcttctcttc tgattttttc tccgcttttt cgcttgaatc agtcgctacc tcttcctttt
    20461 tatctctttt ctcttctttg attttgactg aaggaaacag aaactcatat tggctcttag
    20521 acgtacgaac agtcgtcacc aagcttgttt tcttgttttg atagcttacc tgacctagat
    20581 taaagacctg ttccccactt tcttgctcgg ctttatcctt ggttcgttta gccattgcaa
    20641 aagcaaccaa tttttcttta ttcaaagcat agtcttgata gtgggcgact tgtcggttca
    20701 agtaaaattg caacaaaaga ctaaagatgg ctgctatggt gactgcgtag aggagaacac
    20761 ctgccttaac ttttttcttt ttccacacga tagatgaact ccctttctaa gcctttttga
    20821 aactggaaac gaaaatgaac cagttgattg tcctctgtaa tctgagctga tttgaggcca
    20881 taaaccatag gctgataccc ccgtccacta gcatcggttt tacgaaaatc gtctgacttt
    20941 gacttaccga tggcgatgtc cttgccatct tgcttcatgt ataggcgatt gccttctact
    21001 ttttcgaact gcgaacggtc taattctgcc tcaagttggt ccacaaacaa gagccactcc
    21061 ttttgctcgc tttgttgctg gtagcgaact tctgaaatga ggagctgact catagtttga
    21121 aaaaggagta atcccccact gatgacaatg agggcaagta gggattctaa caaggtaaaa
    21181 gccttgacct tatggctctt tgattgccaa caactgttct gaaccatggt agacctccaa
    21241 tcctttttca ctagaaaata cctgaatctc aactccgttg atgcttacct gattttgccc
    21301 cgtctgcagg gccatcttag ctaccctcaa gacttcttcc ttttgcaaga tttttgcttc
    21361 ctcttgccta tttttttgaa tttgtcccaa aaggagggtc gcaatgctgg caaagatagc
    21421 tagagcgact actgcttcca gtaaaatcac tgccctaatt ttttgtttcc ttaatgcgtt
    21481 taatttttcc atttcctaga tataattgat agcgaatcgc tcctttactg gtctgaaatt
    21541 caaccttagc cagggacgaa ttgcccccag ctcggtcaaa tgtaatactt tggcctgatg
    21601 gtgcctgaat tcctttagga actgtcaact tttgactgcc attgctaagc gtctgcccat
    21661 ctaaatttag attagtcttt tgctgactgg ctacactgcg tttttgggtt tcccgataga
    21721 gttcttcaaa ctccataaag aaaatctgtt cctctaccgc cgcaaaagtg gactgaacag
    21781 agccggacaa gcccaaggca aggatactca caagacccaa aaccaagaga ctttccagca
    21841 tggtaaaggc cttaatcatt gactttacga tttgctcctc catttttatc atggtattct
    21901 ttataagctt tagcctgttc ttccgtgatg cgtccatctg cttgtaactt tcttaggcta
    21961 gcatcttcat tcttttctaa gctataaagt tctgcctggc tttccaccac cttaacaaca
    22021 gctgcttttc ctttgtcatt gactgcttct ttttgcttgg tcagattagg tacaaagagc
    22081 aagaaaagca cgctgataat cagcaagacc accaacattt caatcaagga tagtaaaatt
    22141 ctcactcttt tctatctcat acatccttac cgaatgcaac acgagatcac gatacttcca
    22201 agtgctgacc agatactcaa taacctcttg gtcctctatc ctgcattcca taagtaataa
    22261 tagcttgacc gtgtattcat tcttcaaaat cggaacctga taagtcacat ctacccaatg
    22321 ctcaaaacct aagtctgtct gctctacatt tgctagttca atatttaaaa tcttcatttt
    22381 tattcctcct acttatctat tcgtaaaaga agataaaaag ttatgaaaaa atcactattt
    22441 ttttattttt aacaaaacac cgtttttgac aataatcaaa aaataaaaag gagctattat
    22501 taacaaaatg gcgtttttgg caataatacc ctgccattcc tcctccctat tcttcatgta
    22561 aacgcttttt tgaagaatca gagcaaataa aaaaccgcaa gcctgagcct gcggtgaaag
    22621 aacaatttag aaagtttcct ttctatttat ttaactgtaa tcaagccatc tggctctact
    22681 gtgaattctg gcttgtctgc cagtgttccg tctggtttga ggtagtacca gcctgttccg
    22741 tccgctgact ggataaaggc atttgatacc attgcgcctt ctttagcgtc taagtagtac
    22801 catgtgtcct tgtacttgac ccagcctgtc ttcatggcac cttctacatc aaaatagtac
    22861 cacttctcag cgattttctt ccagcctgtg gccatttcgc ctgattggtc aaagtagtac
    22921 caattaccgt ctgtgtgctt cttccagctg tctgaaagca tatagcctga gccatcgaaa
    22981 taataccagg taccgttgat tttctcaaac ttatcttttg gataagagcc gtctaaatgt
    23041 acgtaccagt agccagtgtc gttcttcttc caacctgctt caacgctcaa accgttttca
    23101 atatcatgct taaactgttc acggctaatg ccccaacttg caagatatgg ataagggtca
    23161 acgtggtctg agtggttgtt tggttggtta ttcgtgcaat actcgtgcgt tttaattcca
    23221 gctaaactcc ctgtatcaag cgttttcggc aaacctgctt catctgctag attgcgtagc
    23281 aattcgatat aaaggcgata gtcagccata aactcttcct tagttgaatg gctttcaatc
    23341 agttcaaccg ctgcataggt ctcagcattc caaccgcccc caacatccca acttccgttg
    23401 ttcacaagac ctacttgcat gacacggccg tttccgacaa catgtgaaaa gaaccctagt
    23461 tcagggtcct ttctatagtg gtaatcagct tcattttgag cggttgagtt acggttgcct
    23521 gttgagtggg cgtgtacttg tcgataaggc tgcaccccaa cctggggcaa gcctgtacgt
    23581 agtctgcttg tatcgatatc cattactctt gtcctttcca agcgtcgttc atctgcttca
    23641 ctgctgactc tacgaaggtg tctaagtctt tgtcagtcat gctaatattg tattttgtaa
    23701 gctcagcacg gactttagca cgagcctgtg ccagtttttc atctcccttg tagccagttt
    23761 cagcagctac ctgctccacg gcatttactg catttttggc caagatttca acgattttga
    23821 tggtcttttc tccacctttt tgaaccaggt agtccttgac tgccttgact gcgataccag
    23881 ccaaaataac aaggatgctg attgctccat tagtaatgat ttcagtaatt tgttgcattt
    23941 gttattctcc tttttcgatt tcttccatgc ggtcgttcat gcgaaccatt tctttttgaa
    24001 tgtctccgac cgtgtgagtg attgtggtta attctgtagt ggtcttttct aggtgagtca
    24061 tcaaacgctc ttctcgtcta ttagagtcgg cctttgattg ctcgtgcaaa tccataatct
    24121 tcttctctcg cttgtccgaa gtcttgataa gatatcgaat gataataaaa aaaagcaaga
    24181 taaacaaaat cgcccaagct acctgacttt gagcgatttt ttcagcttct tcaattggca
    24241 tacaacctcc tattctttag gttctaccgt tggaaccgtc cagtcaggat tgccctctgc
    24301 atcaaatttc atgatataga attcatgatt caacagaacg gctacgttga ttgttgcgat
    24361 tgtaccaccc cactggttga acgcccaaac ggtttcaaca tccttgaatt ggcgacggcc
    24421 atttacgatc acaggacgtt tttgaacatc acgatacata tagaagtcat cgcttacatt
    24481 cttgcaacga atgaactctc cattttcttt catgtagcgc aaagcactcg caagatcaaa
    24541 tggttctgtg atttttgtaa ggtctagtaa gttatctgtg ttttgaattg tttctgccat
    24601 gtctattctc ctttgtctgc tggtttagtt tgttcatcaa gcagagcttc cagctcatcc
    24661 actcgtgctt gaagtctttg attctcttcc ctttgctcat tcaactgaat actcaagata
    24721 ttacttgtaa tcatcgaatc tgttgaagtt gttgacattt cacgaattgt catttgtaag
    24781 gcttggttaa gctgttctgt gttcattttc taagttctcc aatctgtgtg ttcgttttct
    24841 attttcaaga gcaagctcct gaattgcttt aaagtgtgat attggtcaac atgttgttat
    24901 tcatgctatt gttttctcca ttttttctat tttttgattt aattcttgaa tagccttgat
    24961 taagtaagga actaaagcgg tatagtctat atgcagatag ccatctggat tctcaggatc
    25021 tcgtgagaca atttttggaa cgatggtttc agcctcttga gctattagac caatctcctc
    25081 atgtttctta ttttcgatga aatcaaatgc aaccattctt aatctgttga ttttgtccaa
    25141 ggctttcaca gctgtatctg tgatgttctc ttttaagcgt ctgtctgatt tttgttccat
    25201 ccaatacttc a
//
LOCUS       DAVKZI010000031        24729 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKZI010000031 DAVKZI010000000
VERSION     DAVKZI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.032"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..701
                     /locus_tag="VXB18_001480"
     CDS             <1..701
                     /locus_tag="VXB18_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0382663.1"
                     /translation="LLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCL
                     DIIFPELDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAP
                     RSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVIL
                     AEIRNIHSFDNPAQLQAFAGLDSSIYQSGQIDLAGRMVKRGSPHLRWALIQAAKACAR
                     FSPAFKAYLKTKLE"
     gene            complement(1002..2891)
                     /locus_tag="VXB18_001481"
     CDS             complement(1002..2891)
                     /locus_tag="VXB18_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0382664.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3029..4594
                     /locus_tag="VXB18_001482"
     CDS             3029..4594
                     /locus_tag="VXB18_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0382665.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4594..5334
                     /locus_tag="VXB18_001483"
     CDS             4594..5334
                     /locus_tag="VXB18_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0382666.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(5443..5658)
                     /locus_tag="VXB18_001484"
     CDS             complement(5443..5658)
                     /locus_tag="VXB18_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382667.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(6542..7792)
                     /gene="ilvA"
                     /locus_tag="VXB18_001485"
     CDS             complement(6542..7792)
                     /gene="ilvA"
                     /locus_tag="VXB18_001485"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0382668.1"
                     /translation="MLSSKDIIKAHKILNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7842..8198)
                     /locus_tag="VXB18_001486"
     CDS             complement(7842..8198)
                     /locus_tag="VXB18_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0382669.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8436..8672)
                     /locus_tag="VXB18_001487"
     CDS             complement(8436..8672)
                     /locus_tag="VXB18_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382670.1"
                     /translation="MLADQNKADWSYDENTVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSSFERAGATKSARYIAKWILRNKKH"
     gene            complement(8779..9801)
                     /gene="ilvC"
                     /locus_tag="VXB18_001488"
     CDS             complement(8779..9801)
                     /gene="ilvC"
                     /locus_tag="VXB18_001488"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0382671.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVTEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9867..10343)
                     /gene="ilvN"
                     /locus_tag="VXB18_001489"
     CDS             complement(9867..10343)
                     /gene="ilvN"
                     /locus_tag="VXB18_001489"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0382672.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10336..12036)
                     /locus_tag="VXB18_001490"
     CDS             complement(10336..12036)
                     /locus_tag="VXB18_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0382673.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12237..13904)
                     /locus_tag="VXB18_001491"
     CDS             complement(12237..13904)
                     /locus_tag="VXB18_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0382674.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13907..14272)
                     /locus_tag="VXB18_001492"
     CDS             complement(13907..14272)
                     /locus_tag="VXB18_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0382675.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14429..14617)
                     /locus_tag="VXB18_001493"
     CDS             complement(14429..14617)
                     /locus_tag="VXB18_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0382676.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            14822..16219
                     /locus_tag="VXB18_001494"
     CDS             14822..16219
                     /locus_tag="VXB18_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEV0382677.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHGNRNRKPKHAIPDEIKERILKKYLSYETYKPNVLHFCELLAEEEGIKLSDT
                     TVRKILYKKNILSPKSHRKTKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSR
                     PRKKFSGELIQMDASPHAWFGPETTNLHLAIDDASGNILGAYFDKQETLNAYYHVLEQ
                     ILANHGIPLQMKTDKRTVFTYQASNSKKMEDDTYTQFGYACHQLGILLETTSIPQAKG
                     RVERLNQTLQSRLPIELERNNIHTLEDANTFLLSYIQTFNEQFGNKTKLSVFEEAPNP
                     SERNLILARLAERVVDSGHHIRFQNRYYMPVEQGKEVYFIRKTKALVLKAFDGDIYLN
                     IADKIYHTKELLDHELYSKNFEQEPEQKKERRKYIPPQTHPWKLTSFKQYLHKNKKDY
                     EEFTSEELHSPQLQV"
     gene            complement(16507..16683)
                     /locus_tag="VXB18_001495"
     CDS             complement(16507..16683)
                     /locus_tag="VXB18_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0382678.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(16794..16991)
                     /locus_tag="VXB18_001496"
     CDS             complement(16794..16991)
                     /locus_tag="VXB18_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0382679.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(17246..18790)
                     /locus_tag="VXB18_001497"
     CDS             complement(17246..18790)
                     /locus_tag="VXB18_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0382680.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            19003..19305
                     /gene="gatC"
                     /locus_tag="VXB18_001498"
     CDS             19003..19305
                     /gene="gatC"
                     /locus_tag="VXB18_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0382681.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            19305..20771
                     /gene="gatA"
                     /locus_tag="VXB18_001499"
     CDS             19305..20771
                     /gene="gatA"
                     /locus_tag="VXB18_001499"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0382682.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLEDIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            20771..22213
                     /gene="gatB"
                     /locus_tag="VXB18_001500"
     CDS             20771..22213
                     /gene="gatB"
                     /locus_tag="VXB18_001500"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0382683.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            22342..22902
                     /gene="efp"
                     /locus_tag="VXB18_001501"
     CDS             22342..22902
                     /gene="efp"
                     /locus_tag="VXB18_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0382684.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            22924..23313
                     /locus_tag="VXB18_001502"
     CDS             22924..23313
                     /locus_tag="VXB18_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0382685.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            23306..23728
                     /gene="nusB"
                     /locus_tag="VXB18_001503"
     CDS             23306..23728
                     /gene="nusB"
                     /locus_tag="VXB18_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0382686.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAINEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(23778..24155)
                     /locus_tag="VXB18_001504"
     CDS             complement(23778..24155)
                     /locus_tag="VXB18_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0382687.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(24518..24703)
                     /gene="briC"
                     /locus_tag="VXB18_001505"
     CDS             complement(24518..24703)
                     /gene="briC"
                     /locus_tag="VXB18_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0382688.1"
                     /translation="MTATETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
BASE COUNT         7502 a         5583 c         4463 g         7181 t
ORIGIN      
        1 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagaactaa
       61 aaatactggc tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat
      121 acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag
      181 aatataccta ccaactcttg acacgctacc ctaatcctca gaaaaggctt gaggcaggat
      241 ttgataagct gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag
      301 tcgcacctcg ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaatca
      361 tcaaacatta caagaggctc attgacaagg cggaaacatg tgtcaatgac ttgatggctg
      421 agttcaactc ggtcatcacg acggttactg ggattggggg tcgtttaggg gcggtcattt
      481 tagccgagat tcgaaatatt cattcctttg ataatcctgc tcaattacaa gctttcgctg
      541 gactggattc ttctatttat cagtcaggtc agattgattt agctggaaga atggtcaaac
      601 ggggttcccc tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt
      661 cacctgcttt taaggcctat cttaagacta agttagaata aggaaaacat tacaatgtag
      721 ccatcatcca ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct
      781 gccatttgac gaacaaaaag tgatgtaatt tctgaaatta acacaggatt acctttgaaa
      841 aaatggactt tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt
      901 gaaataagaa atagtttaga taaaactatt gacttttctt atagtttgtc tttcttctat
      961 cttccattat atcatacttt ttcagtctat ggtagctctc tttaaaaggc tccgatactg
     1021 ccgccacctc cgcctccaga gaagccaccg ccagaacttc cacttccaga agatacggag
     1081 taggtacttg ctgtatttgc gacactagca taatggctca tttgcgcgct tgaatgataa
     1141 aacatactgt gccagccata agctacatag agattgatat ctggattttc aacttgaatc
     1201 tgatgaacct tcatcaaatg actaaccttg tccgcatagc caaataaggt tgcatagacc
     1261 aagagacgat tccaaacaac aatactttcc aattcagcct tatccagtcg tgcaatctca
     1321 cgtaacatat tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga
     1381 acaccatcac gattatctag tcgaagcttc caataataga aaacagacaa aactaaccct
     1441 agaaaaccaa gtattggcaa agggaggtaa agatagccat gaacgtctaa actgtacaag
     1501 aacaaaccaa atccgataaa taggggcaag atagtcaaga cacccatacc cacttgcaaa
     1561 gccttttcca aaccagttaa aggacgatag taatctggga gcccccagaa ggaaactcgt
     1621 tttctcactc cttcttgcat ctggttcaat acctcttcaa aagaagattt gagttgaagc
     1681 cctcttgctt gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat
     1741 accttgtaat ccgcaaacaa attggaaaga gtttcttctt ttttacctga aaaagctaga
     1801 tttaggcagt ctttctcaaa gcttgacaaa ccatcttctt ttactagcct caaaccaact
     1861 gcatctcctt ctgaaatgat agagacattc ccacggtcta tcacatctag caaggtagct
     1921 tgaataagtt gatcaaaggt gaattttcca gctcccttga ccaagggact cacttcctcc
     1981 aaggaggtcg agtagactgc ttctgataaa accataggct ctaattccat tgggggttca
     2041 tagagacgat gatttttggc atatttgact gaaggagtgg tctttcttct ataaataaaa
     2101 tagaagcaga cactcaataa caaggagatg gaaaggatcg aagggaagat ccaagtaagt
     2161 agttgtttac tttgctcttt ttctttaacg atcgaatcct ctatcttatt aaactcttct
     2221 aaacgattcc ctttcaatcc ctgatcccta gcgctagcaa aatcggtccg aggccaatag
     2281 gcatgcaact caactccacg cttagccgga agattgtcta aacggatagt ataatcaagg
     2341 ttactctttt caatcgttcc ctctctaaaa agtttccctg tatggaaaaa gagtttttca
     2401 gcccccttgt ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc
     2461 agaggttgcc aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc
     2521 cagacgaggt caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta
     2581 taaccatccg cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc
     2641 gcggcctgaa cctttggatg agggtcaatg tcaaacccgc taggcatctt accagcacgt
     2701 ccaagtccca cgatttgtcc cttaaagtcc tcctcaaact ggtaaactat cttctgtcta
     2761 aactctgccg tattatctgc atgaatatac aaatcccctt gataagagtt tatcttgaaa
     2821 tcaatggcaa aaacagagag tggaagaagg caaaacaagc ctaacaccag taagaaaaaa
     2881 gtttttttca tcaactaagc ccccttttta tctttcttat cattatagca ttttttcgta
     2941 agtaaaggct tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat
     3001 tttttaatag atcagaatag gagaaatcat gagaaaaata tacttatcta ttttcacaag
     3061 tctcttgctg atgctaggac ttgtcaatgt tgctcaagcc gatgaatatt tacgcatcgg
     3121 gatggaagca gcatatgctc cctttaactg gacccaggat gatgatagca acggagctgt
     3181 caaaatcgat gggaccaatc agtatgccaa cggatacgat gttcaaatcg ccaagaaaat
     3241 cgctaaggac ttaggtaaag aacctttggt tgttaaaacc aagtgggaag gtctagtccc
     3301 tgcccttact tctggtaaga ttgacatgat tatcgcaggt atgagtccaa ctgcagaacg
     3361 caaacaagaa attgcctttt cgagcagtta ctacactagc gaaccagttt tgcttgtcaa
     3421 aaaagattct gcctacgcaa gtgctaaatc tttggatgac tttaacggtg caaaaatcac
     3481 ttctcaacaa ggggtctacc tctacgactt gattgcacaa atcccaggtg ctaaaaaaga
     3541 aacagccatg ggagacttcg ctcaaatgcg acaagctctt gaggctggtg tcattgatgc
     3601 ttatgtttct gaacgtccag aagcactgac tgctgaagct gcgaactcta agttcaagat
     3661 gattcaagta gaacctggtt tcaaaactgg ggaagaagat acagctatcg ctatcgggct
     3721 tcgtaaaaat gacaatcgta ttagccaaat caatgccagc attgaaacca tttcaaagga
     3781 cgaccaagtt gccctgatgg atcgtatgat caaggaacaa cctgccgaag ctacaacaac
     3841 tgaagagact agcagtagtt tctttagcca agtcgctaaa attctttctg aaaactggca
     3901 acaactcttg cgtggtgctg gtatcactct tttaatctct atcgtcggaa ccatcatagg
     3961 tctcattatt ggacttgcca ttggtgtctt ccgtactgct cctctctctg aaaacaaagc
     4021 catttatggc cttcaaaaac tagtcggctg ggttctcaat gtctacattg aaattttccg
     4081 tggtacgcca atgattgttc aatcgatggt tatctactat ggaactgccc aagctttcgg
     4141 gatcaacctt gaccgtacac tggctgctat cttcatcgtt tcaatcaata ccggtgccta
     4201 catgactgaa atcgtccgtg gtggtatcct agcagttgac aagggacaat ttgaagctgc
     4261 gactgctctt ggtatgaccc ataaccagac catgcgtaag attgtcctac ctcaggtagt
     4321 ccgtaacatc ctacctgcaa ctggtaatga atttgtcatc aatatcaaag atacatctgt
     4381 attgaacgtt atctctgttg tcgaacttta tttctcagga aataccgtgg caacacaaac
     4441 ctatcaatac ttccagacat ttacaatcat cgccgtgatt tactttgtcc tcaccttcac
     4501 cgtaacacgt atcctacgct ttatcgagcg cagaatggac atggatacct acactacagg
     4561 tgctaaccaa atgcaaacgg aggatttgaa ataatgacac aagcaatcct tgaaattaaa
     4621 cacctcaaaa aatcctatgg acaaaacgaa gtgctaaaag acatttctct cactgtccac
     4681 aagggagaag ttatttctat catcggaagc tctggaagtg ggaaatcaac cttcctacgc
     4741 tccattaacc tacttgaaac gccaactgat ggacaaatcc tttatcatgg acaaaacgtc
     4801 ctcgaaaaag gctatgacct cacgcaatac cgtgaaaagt tagggatggt tttccaatcc
     4861 tttaacctct ttgaaaatct caacgttctt gaaaacacaa tcgtcgctca gacaactgtc
     4921 cttaaacgcg aacgcacaga agctgaagaa attgccaaag aaaacctgga aaaggtcggc
     4981 atgggagaac gctactggca agctaaaccc aaacaactct caggtggtca aaaacaacgt
     5041 gtggccattg ctcgtgccct ttcaatgaat cctgacgcca ttctctttga tgaaccaaca
     5101 tcagctctcg atccagaaat ggttggagag gtcctcaaaa tcatgcaaga tctggctcag
     5161 gaaggcttga ccatgattgt cgtaacccat gaaatggaat ttgcccgtga tgtctctcac
     5221 cgtgttatct ttatggataa gggcgtgatc gctgaagaag gtaaaccaga agacctcttc
     5281 accaatccta aagaagaccg aacaaaagag ttccttcaac gctatctcaa ataaaaagaa
     5341 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     5401 tctctactac ttgaaggtca agaatccgcc gttatccaaa gattaatctt caaatttttc
     5461 atgatttttt tcatagaaat caattaggcc tagggctgtt tcaaatgaaa tattttttac
     5521 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     5581 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     5641 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     5701 gtttttacta cttttgtcaa taaaaaaaca tgtattcaac gaaaataatt agttcagaat
     5761 tttagcttca gaattttctt acttcctttt tgaatccgat aatatatagg ttttactagt
     5821 ctctacacca taaatatttg ctaataaaaa tactgtatta ttaccctctt aaggtgcgaa
     5881 attattcaag ttcttaaaaa atgcttctct atttccgtaa gatagcttat ttcttcgatt
     5941 taagaactga agatgatagt tctaaccttt agaaatccaa gccttcacta gctcaaaaac
     6001 tcctatcttt cttcctcaat aaatcatctg agagataggt attccttata tccttcaaat
     6061 tcatcactcc tttggatatt gaggtgctag cctagaagca gacacccgat tatctaaacc
     6121 atccttaata gagatgacaa gacagataag ctcagttaat tacttatata tctttttaat
     6181 atggtatatt tgtcaacaaa aagaaatcaa atcatacctt atactcaatg aaaatcaaag
     6241 agcaaactag gaagctagcc gcaagttgct caaaacactg ttttgaggtt gcagatagag
     6301 ctaacgtggt ttgaagagat tttcgaagag tattaaagac agtgtgacta tgcttgtcaa
     6361 tagataggaa atcaaaatga aggatggaaa tctgagccaa acatcataag tgctataatg
     6421 aacagaagta agaattgcac gataagtttc ctaaaaccat agaaatcgtc ccctttcttc
     6481 atcttcatta tagcacatat acatcagttg tacaaataat atgatatttt tttattagtc
     6541 ctcagacaag catattataa agcgtttcat taccatttaa gttaatataa gctggatcaa
     6601 aaccttccat tctacgaatc aaacctgcat aatcatgctt atctgctaaa gcgatcccaa
     6661 ttaatactgg gcctgttccc ttgctagctc gtttgatata ctcaaaacgt gtgatatcat
     6721 catttggccc caggatatca tttacaaact cacgcaaagc tcctggacgt tgtgggaaat
     6781 tgaccacaaa gtaatgtttg ataccatcat aaatcaaggc acgctcttcc atttctggca
     6841 tacggttgat atcattattt cctccagaaa tgatacaaca aatggttttc cccttaatat
     6901 attcagctaa aacctctaaa gaggcgatac tagccgctcc agcaggttct gcgactatcc
     6961 cttgcttaga gtaaaggtca atcaaggttt cagaaatcaa tccctcatcg acacctacca
     7021 aagttttaat atgttgacga gttgcttcat aggtcaactg acctaccttt tgcacagcaa
     7081 tcccatccgc aaatttatca atttccttga gtttgactgg acctccagcc tcaaaggcag
     7141 ctttcatgga acgcgctcca ttcgcctcta ctccgataac ctcaatctct ggacttgttt
     7201 ccttgatata ggtagaaacc ccggcaatga gaccgccacc accaacagga accaagacag
     7261 catcaaaatc aatcgattct tttcgagctt cttctaaaat ctcataagca actgttcctt
     7321 gacctgcttg aacatgagca tcatcaaaag gatcaataaa ggtacgattt tcagagactg
     7381 taaattcttg agctgctttg gctgaggcat caaaggtatc tccaactagt ttaatagtta
     7441 caaaatcccc accaaaaaag cgaacctgac caatcttttg ttgtggcgta gtaataggca
     7501 taaagatagt agcaggaatt ttcatttcat tacaagtata ggctactccc tgcgcatgat
     7561 ttcccgcaga agcgcagact accccacgtt cacgttcttc cttgctgagc tgggaaatgg
     7621 cataataggc accacgaatt ttaaaggagc gaacacgctg ggcattttct tttttcaaat
     7681 aaatcttagc accatacttc tccgataaat aatgatcgta atccagtgga gtattcacaa
     7741 ccacaccgtt caagatcttg tgagccttga ttatatcttt tgaacttaac atataaaacc
     7801 tctttttcta taaaaaacag tcactaatga ctgtttttta gttattcatc tccgaaaact
     7861 tcagtaacac tttcatggta tttatgagcc atacgaatcg aaaactcttt aggaagctca
     7921 taacgatttg tggaaatcca atcatataac cattctacca aactttcttc actatcatta
     7981 cgatggaaga taaaatagtt taaaatttct ttatattcta catcattcaa atccaacgtg
     8041 tctacaaatt gactacgagg aacaaaatta gaatctaatt ttcttagttg atctgtcaat
     8101 tctcccaatt gtaaatccaa ctgaaaaaat agtttttgca gttgcctatc agtttcatca
     8161 catcctgtct tgatagaaaa caaattggta atattcatat gatttcaacc cctaaataag
     8221 tacatctaat atcccacgaa tagctgaagc taaagttttc gcagtccagt catttaaacc
     8281 cgattctttc aatccagatg caataatttg ctctatttga tataaaccgc catctatcgt
     8341 ctcatttatt ctgcgaagag gaccttcaat ataggataaa gcttctccga atctaacagc
     8401 tgatttaggt cctaatgatt taccaactat atttgttaat gttttttatt tctcaaaatc
     8461 catttcgcta tataacgagc agatttagtc gcaccagctc tctcaaacga agaatgaatt
     8521 tcaagacctt cttctctagc tatttgtgcc aatttgaaga attgttcaaa ggtcatatgc
     8581 aacctaccat cttcaaaatt agcatcatca taaatgttaa ttacagtatt ttcatcatac
     8641 gaccaatctg ctttattttg gtctgctagc actattaccg acggtgtaat tacattatac
     8701 aactagaacc aataataacg atgcaatttt tctcataatc tttttcataa aatcatctcc
     8761 agcgctatat atttctaatt agttatagat tttgaatgca tcatcgtcgt ttttaccaac
     8821 gaatggcatt gctttacgca attctgcacc aactttttca atttcaaggt tagctgcttg
     8881 ttcacggtaa gcagtcaatt ttggacgtcc agctttatag tcatttacaa agtcatttgc
     8941 aaatttacca ttttggatgt ctgccaagac agccttcata ttttctttaa cttgttcagt
     9001 gattacacgt ggacctgata catagtcacc gtattcagca gtgtttgaaa tagattgacg
     9061 cattttcttg aatccacctt cgtagatcaa gtcaacgatc aatttcattt cgtgaagaac
     9121 ttcaaagtaa gccaattctg gagcgtaacc tgcttctgtc aagacttcga aacctgcttc
     9181 gataagggca gtcaaaccac cacaaagtac agcttgttca ccaaacaaat cttcttcagt
     9241 ttcttctttg taagttgttt caagaagacc tacacgagcc gctccaacac ctttacacca
     9301 gtccatagca atgtttttag catttcctgt tgcatcttgg tatactgcat aaagagctgg
     9361 aacaccaaat ccttcttcgt aagtacgacg taccaagtgt cctggtcctt taggagcaca
     9421 catgaagaca tctacatccg caggaacttt gataaattca aagtggatgt tgaaaccatg
     9481 ggcaaatcca actgcgtttc cagcttccaa gtttggagcg atttctgctt cgtacaattc
     9541 ttgttgaatt tcgtctggcg ccaagatcat gataacatca gccaacttag tagcttctgt
     9601 tactgtgtaa gtatcaaatc catcttcttt tgctttatca aaagatttac ctggacgtac
     9661 accgataata acgtcacgac ctgaatcacg caagttttga gcatgcgcat gcccttgtga
     9721 accataaccg ataacggcga tttttttacc gtcaagtgct gctactttaa catctttttc
     9781 atattccatt tgaactgtca tagcttttct ctcttttcta ttatttattg ccttttaagc
     9841 tggtttaaca aatttaagtt ggatttttaa tcgcgggtaa atccagttgc acccgttcga
     9901 gcaatattgc gaataccgta tgggcgaatg actcgcaata gggcttcgct cttttctgca
     9961 tttcccgtca tctgaatggt aatcgagctt ggcgctacgt ctaccactgt tgcacggaaa
    10021 ggttgaataa tcgctaaaat ctcagctctc ttctcagctg gcgctgacat cttaaccaaa
    10081 atcacctcgc gctccaaatg aggcttgtct gtaatatctc gaatgcgaat cacatcaatc
    10141 tgacgattga gctgtttgat gatttgctcc acttcatcat gagaagcaac atcaataata
    10201 atagtgatac gcgatacatt cggatcttct gttgctccaa cagagatgct ttcaatatta
    10261 acctgacgac gagataggac acctgtaaag cgattgagga ctcctgaacg attttgtagt
    10321 tttgctgtta acattctacg catggaactg cacccccaac atctcatgat tactcttacc
    10381 agccggtacc attggtaaca cctgttcctt acgagaaata tctacctcaa ttagcatagg
    10441 aacatcctca gtgatgactt caaggtcttg agccaaggtc tcaggattgt caaacttata
    10501 gtttttaata ccataagcct gcgccatcaa ttggaaatca ggaagggtat caaagaccga
    10561 ctctgatgtt ctgccttcat agaaggattc ctgccactgg cgaaccattc cgagtgaatg
    10621 attgttcagc ataaccacct tgattggcac cttgtaaata ttcaaaatag ccaactcctg
    10681 gttggtcatt tggaaaccac catccccaac aaacaagact acttccttat ctgggttagc
    10741 aattttagca ccgattgctg ctggaattcc aaagcccatt gttcccaaac cacctgaagt
    10801 cactaactga cgttcatttt ggtagggata atactgagct gtccacattt ggtgttgacc
    10861 aacgtctgtt accacaatgg catctccatt cgtcaattca ccaattcgtt caataactgc
    10921 ttgcggttga accacacgct ctttcttgtc ataagaacga acacgattct tgtctttagt
    10981 gactttctca atccactttt cagtattgtt gtgaactgtt ggttctgcta gcaacatttg
    11041 caaggccttc ttagcatctc caactacagg aatgtctgca ctgataatct tgccaatctc
    11101 agctgggtca atatcaatgt gggcaacctt agcattctta gcgaaagtct taggattccc
    11161 cgtcaaacgg tcatcgaaac gagaaccaat actaatcata aagtccgctt ccgtcatggc
    11221 aatatttgct gcgaatgacc cgtgcatgcc tcccattcca agaaagagtg ggtgactcgt
    11281 tgcaatcgtt ccttgtccca aaagactggt taccactgga atttgatagc gttctgcaaa
    11341 ttcatttagt tccgtagcag cctcagcata actaattcca ccaccagcta acaagactgg
    11401 ctttttagcc ttggacaatt gcttcaagat tttcttgatt tgcatatcat tcggctcaag
    11461 agtcggctga taacttggta aattcacttc tggtgaataa atgaagtctg tttctaaagc
    11521 agatatgtct tttggtaggt caattacaac tggccctgga cggcctgtag ttgcgatatg
    11581 gacagcttcc gtaatgatac gcggaatatc agctgtctca cgaacttggt aattgtactt
    11641 agtgattggc atggtaattc ccacgatgtc tgcctcctga aaggcatcct tcccaatccc
    11701 tgctcgcgcc acctgacctg taaagaccaa aaggggaacg ctatcgctca tagcatccgc
    11761 aatccctgta atggcatttg ttgctcctgg tccactagtg acgacggcaa cacccaactt
    11821 tccagttgat ttggcataac cttcagcttc atgcaaacaa ccttgctcat ggcgccctag
    11881 aatgtggcga atgcctttaa aattatatat cgcatcataa aaaggcaaaa ccgcaccacc
    11941 aggataacca aagatggtat caactcctaa atcacgaagt gtttccaaaa ctaggtccga
    12001 ccccgtctta ggagattcta aactgatttt ctccattgtt cccctttctt tcctcttaaa
    12061 aataacttgt tactatcata ccattttttc aaaatttttc aagataaaag aagaaatttt
    12121 ctgaattttc tattttaacg tttatttatg aatgttattt ttgtttttat taaaaagata
    12181 ccgatttcat ttactaaaaa agaaaaaaga actgatttct cagtccttca ttaatcttat
    12241 tccacactaa ataggtatgg gtaaacaggt tgttgacctt ggtgaatctc gacttcaacg
    12301 tcttcgaatt cttctacgat ttcttgagcg atttcattag caagttcttc gcttccgtct
    12361 tcaccgacat agaaggttac gatttcactg tcttcatcca acatatgttt caaggtttca
    12421 gtcaatgttt ggtgcatatc agggtttgac acaagaattt ttccatccac catacctaga
    12481 ttatcgtttt catggatttc taagccatcg atcgttgtat cacgcacggc tgttgtgacg
    12541 cttccgctaa caacatcgct aagagcagct gtcatacgct cttggttttc ttcaatggac
    12601 ttgcttggat caaaggcaag aagacttgtc ataccttgag gaagagtgcg agcctctacc
    12661 actactgctg gttgctccaa aacttctgcc gcagattgag ctgccatgaa gatgttcttg
    12721 ttgtttggca agaagatgat gttacgggca ttgacctgtt caacagcctt gataaagtct
    12781 tctgttgaag ggttcatggt ttgaccgcct tcgataacat aatccacgcc ttgagaacag
    12841 aagatatctg ctagaccttt accagccacc acagcaatca aagcatactc tttttcttca
    12901 gccgacttga taacttgagt agcttctttc tcaacctgtg cttcgtgttg gttacgcata
    12961 ttgtcaactt ttaccttgac caagctacca tatttgagac cttcttgcat aacaagtcct
    13021 ggatcttctg tatgaacatg gactttgaca atttcatcat cgttaacaac gaggagagaa
    13081 tccccaagct catccaagta gttacggaat tcatcgtagt caaaatcttt agcataggtt
    13141 ggaccttgct taagagctac catgatttca gtacagtaac caaacgtgat gtcctcagtc
    13201 gctacgtgac cagctacaga cttatgatgc tctacattga tcatctcact catgttggca
    13261 ggagtcgcta caaagtcctc agatgcaata tattcgccag taagggctga aaggaaacct
    13321 tcgtagatga agaccaatcc ttgaccacct gagtccacaa cgccaacttc tttcaatact
    13381 ggaagcatgt ctggtgtttt agctagagct gttttagcac cttccaaggc tgcgcgcatg
    13441 acttcaacag tatcatctgt ttgctcagct tttttcttag caccgatagc agctccacga
    13501 gaaactgtca aaatcgttcc ttcaacaggt ttcatcactg ccttataggc aacttccaca
    13561 cctgattgga aggccagagc caagtcttga cctgttaact cgtctttatc cttgatagct
    13621 tgggaaaatc cacggaaaag ctgagatgta atcactcctg agttcccacg cgcacccatc
    13681 aaaagccctt tggcaagaat gctcgctact tctccaactg tagaagctgg cttgtctgca
    13741 acttctttag caccattttc aatggtcatt cccatatttg tcccagtatc tccatctgga
    13801 actggaaaga cgtttaatga attgacatat tcagcttgct tattcaagcg agttgatgca
    13861 gcctgcacca tttcttgaaa taagctagta gtaatctttg acacggttat tctcctacaa
    13921 ctttgatatt ttgaatgtag acatttacag tctgagcagt aattccaagc tggttttcca
    13981 agctaaaggc aacacgctct tgaatgtttt ttgacacttc actaatcttt gttccgtagc
    14041 ttaacacggt atatacatca actgcaatac tgccatcttc ggctgccttt acgacgacac
    14101 ctttagaata attttcctta cctagcaggg cttggaaatt atctttgagg gcatttttac
    14161 tagccatacc gaccacacca aaaatctcag ttgctgctcc acctacgacg gttgcaatca
    14221 cttcatctgt tagttcgatt tgaccatctt ttgtattaat ttttacagtc atccttttta
    14281 cctcaactag ttgatactct attttatcat atttcagccc aagtgtaaaa gcagaatgat
    14341 gtatcagcgg atatttactc tatttttcaa acgatgttat acccacaata aaagaaaaaa
    14401 gaccctaagg tctcctttgc ttttattatt aaacgcgttc aactttacct gatttcaaag
    14461 cacgagctga agcccaaact tttttaggtt taccatcgat aagaacagta actttttgaa
    14521 ggtttggttt tacggcacgt tttgtttggt tcatcgcgtg tgaacggttg tttcctgata
    14581 cagtcttacg acctgtaaag taacatactt tagccattgt gttttcctcc tattagatct
    14641 aatatagcgg atgtgctagc accacatacc gtactatgtt atcacacttt cttgtttttt
    14701 gcaagggaat tggaagattt tttatttgtg ttgtgattcg aatgtgataa tgtctttagt
    14761 aaatcgaacg tgaaaatgtc acatttggta gaatagtcat atgaaaagga tccaactgaa
    14821 tatgaatgaa acgaaaaaat atcttgtgat aaaagctata gcccaaggaa agaaaacaaa
    14881 gaaacgggcc tgtgtcgaac tcaatctttc tgaaagacaa atcaatcgtc tgctactagc
    14941 ctatcaacag aaaggaaaag aagctttcag acacggaaac agaaatcgaa aaccaaaaca
    15001 tgcaatccct gatgaaatca aagaacgtat cctaaagaaa tacctctcct atgaaacata
    15061 taaaccaaat gtccttcatt tctgtgaatt actagctgaa gaagagggaa ttaagctctc
    15121 tgatacaact gttagaaaaa tactctataa gaaaaacatc ctttctccta agtctcacag
    15181 aaagacaaag aagagagtaa gaaaacaagc taaactgaac ctgaatcaac ccctagacaa
    15241 tccaatctta ccgacggcta aagacttcct ggaagaccct aaaaaggtac atcctagtag
    15301 acccagaaag aaattttctg gagaactcat tcaaatggat gccagccctc atgcctggtt
    15361 tggaccagaa accaccaact tacacttagc cattgatgat gcttctggca atatcctagg
    15421 cgcttatttt gacaaacaag agaccttgaa tgcctactac catgtcctcg aacaaatctt
    15481 agccaatcac ggcattcccc ttcaaatgaa aactgataag agaacggtct ttacctatca
    15541 ggcctccaac tctaagaaaa tggaggacga cacctataca caatttggat acgcctgtca
    15601 ccaactaggg attctccttg agaccacctc tatccctcaa gctaaaggga gagtcgaaag
    15661 actcaatcag acactacaat cacgcctgcc tatcgaactg gaacgaaaca atattcatac
    15721 attggaagat gccaatactt tccttctttc ctacatccaa acctttaatg aacagtttgg
    15781 aaacaagaca aaactctctg tttttgagga ggctcctaac ccctctgaac ggaatctcat
    15841 tctagctaga ctggcggaga gagtcgtcga tagtggacac catatccgat tccaaaatcg
    15901 ttactatatg cctgttgaac aaggaaaaga agtctatttc atcagaaaga cgaaagcatt
    15961 agttctaaaa gcatttgatg gtgacatcta cctcaatatc gctgacaaaa tctatcacac
    16021 aaaggagcta ctagatcatg aactctattc gaaaaacttt gaacaagaac cagaacaaaa
    16081 aaaagaaaga cgcaagtata tccctccaca aacccatccg tggaaactca catctttcaa
    16141 acaatacctt cataaaaata aaaaggatta tgaagagttt actagtgagg agcttcattc
    16201 tcctcaacta caagtataat ctatttttcg ctaaatggga agcttttcct taaagaaaac
    16261 cactctatcc cttacattta ggagagggaa agtgaggagt gtaagacaag catttcattt
    16321 gataagaggc ttggagctgt taggctggcg agccaaggct aagactagcc ttggtttagc
    16381 taacaaaaca gcttcaaggg ctcctcgtgt caaatgaaat caaaataatt gccctcaaac
    16441 tctccatttt ttggggacat aatcactttc gattgacagg gaattggaag attttttatt
    16501 tgtgtcttaa atcaggtctt gcgtgacatt ttctgctctc cacatgccat cgttgattaa
    16561 cagaacacca gaattaaaat tatgtgtata aaaatcatct ctaactgcag ctaagggtat
    16621 agccgtcaag tccaaatccc acagctcatc tatcgatttt cttacaacaa tatctgaatc
    16681 caaatacagt acacgagact cgcttacata ctttggaata aaatacctaa aaaagccgca
    16741 tatgaaagtc cctcaaaggg gagacgataa cctttcagaa tattactgtc aatctaaaca
    16801 ttcacaatct cactattcaa agtctctagt cttttttcca tcaattggaa ccattctcgc
    16861 ggaaggtcat cattaaaaac ataaaactta agattataat gatgaacaca aagagatttt
    16921 attgttgttt caactttatc catataagca ttatctgcac ctaagacaat cgcttttttc
    16981 tcttctttca ctttttatct catttctttt tattcccatc atatgtttct acgtaaccat
    17041 tattttcgcc tattcgttcg taaaaccata ccagtggaga ttttagatga agtcccatta
    17101 cggtttacaa tttttacatt acgacacgga gttttacaaa tcgatttcat ttgccaaacg
    17161 tagttagtga ggcagttagc tagttcgcca aatagcgact agcgtccaac aatttggaac
    17221 tttagttcca attgttggta ctgagtcaca tcttctcctc taactctacg tctggatact
    17281 tgtccgcaaa ccagcggagg gcaaagtcat tttcaaagag aaagactggt tggtcaaaac
    17341 ggtctttggc taagatattg cgacttgacg acatccgttc atccaagtcc tcaggcttga
    17401 tccaacgaac ggtcttttta cccattgggc tcatgaccac ttccgcattg tattcgcctt
    17461 ccatacggtg tttaaagact tcaaactgga gttgaccaac agctcccagc atgtactcac
    17521 ctgtttggta attcttataa agctgaacgg ctccttcttg caccaattgc tcaatcccct
    17581 tgtggaagga tttttgcttc ataacattct tagcagaaac tttcatgaaa atttcaggag
    17641 taaaggttgg cagtggttca aattcaaact tgttttttcc aaccgtcaag gtatccccaa
    17701 cctgataagt accggtatcg taaaccccga taatatcacc tgccacggca ttggtcacat
    17761 tctcacgact ctccgccata aactgggtaa cattagatag tttagccccc ttaccagtac
    17821 gagggagatt gacactcatg ccgcgctcaa attcgcctga tacgatacgg acaaaggcaa
    17881 tacggtcacg gtgacgagga tccatgttgg cttggatttt aaagacaaag cctgagaaat
    17941 ccttgtcata aggatccaca atttcaccgt ctgttttctt gtgaccatgt ggttctggag
    18001 caaacttgag gaagatttca aggaaggtct gcacaccaaa gtttgtcagg gctgaaccga
    18061 aaaagacagg cgtcaattct ccagccagaa tagcttcctc tgaaaactca ttcccagctt
    18121 catttaaaag ctcaatgtca tccttgactt gctcgtagaa aggattgcta ccaaagagtt
    18181 tgtccccgtc ttctagactg gcaaaacgct catccccttt ataaagctct aaacgttggt
    18241 tatagaggtc atacaagccc tcaaaggctt tccccatccc gataggccag ttcatagggt
    18301 agctagcaat gcccaagatt tcttccaatt cttgcaagag atccaaaggc tcacgaccgt
    18361 cacggtccag cttgttcata aaggtaaaga ctggaatgcc acgatgtttc acaacctcaa
    18421 acaatttctt ggtttgagcc tcgatcccct tggcagagtc cacgaccatg accgcagcat
    18481 ccaccgccat caaggtacga taggtatctt ctgagaagtc ctcgtgccct ggcgtgtcta
    18541 agatattcac gcgcttgccg tcgtagtcaa attgcataac agatgaagta acagaaatcc
    18601 cacgttgctt ctcgatatcc atccagtcag atttagcaaa agtccctgtt ttcttccctt
    18661 ttaccgtacc agcctcacga atctcacccc caaagtagag taactgctca gtgatggttg
    18721 ttttccccgc gtccgggtgg gagataatgg caaaggtacg acgtttctta atttcttctt
    18781 gaatattcat aagttctctt tctttgattc tctatttttc ttgtttcaat agctgagaat
    18841 gatttttaca ttggatttta ccattccttt caacactcca ttatatcgga ttttagcatt
    18901 tttttcaatt tctatttctt ttcacttccc cctcccttat ttatgggaaa atatggtaaa
    18961 atagaacaga ctaaaaatca tcatttcacg aaaggatgca agatgaaaat tacgcaagaa
    19021 gaggtaacac acgttgccaa tctttcaaaa ttaagattct ctgaagaaga aactgctgcc
    19081 tttgcgacca ccttgtctaa gattgttgac atggttgaat tgctgggcga agttgacaca
    19141 actggtgtcg cacctactac gactatggct gaccgcaaga ctgtactccg ccctgatgtg
    19201 gccgaagaag gaacagaccg tgatcgcttg tttaaaaacg tacctgaaaa agacaactac
    19261 tatatcaagg tgccagctat cctagacgat ggaggagatg cctaatgact tttaacaata
    19321 aaactattga agagttgcac aatctccttg tttctaagga aatttctgca acagaattga
    19381 cccaagcaac acttgaagat atcaagtctc gtgaggaagc cctcaattca tttgtcacca
    19441 tcgctgagga gcaagctctt gttcaagcta aagccattga tgaagctgga attgatgctg
    19501 acaatgtcct ttcaggaatt ccacttgctg ttaaggataa catctctaca gacggtattc
    19561 tcacaactgc tgcctcaaaa atgctctaca actatgagcc aatctttgat gcgacagctg
    19621 ttgccaatgc aaaaaccaag ggcatgattg tcgttggaaa gaccaacatg gacgaatttg
    19681 ctatgggtgg ttcaggtgaa acttcacact acggagcaac taaaaacgct tgggaccaca
    19741 gcaaggttcc tggtgggtca tcaagtggtt ctgccgcagc tgtagcctca ggacaagttc
    19801 gcttgtcact tggttctgat actggtggtt ccatccgcca acctgctgcc ttcaacggaa
    19861 tcgttggtct caaaccaacc tacggaacag tttcacgttt cggtctcatt gcctttggta
    19921 gctcattaga ccagattgga ccttttgctc ctactgttaa ggaaaacgcc ctcttgctca
    19981 acgctattgc cagcgaagat gctaaagact ctacttctgc tcctgtccgc atcgccgact
    20041 ttacttcaaa aatcggccaa gacatcaagg gcatgaaaat tgctttgcct aaggaatacc
    20101 tcggtgaagg aattaaccca gaggttaagg aaaccattct aaatgccgct aaacactttg
    20161 aaaaattggg tgctatcgtc gaagaagtca gccttcctca ctctaaatac ggtgttgccg
    20221 tttattacat catcgcttca tcagaagctt catcaaactt gcaacgtttt gacggtatcc
    20281 gttacggcta ccgcgcagaa gatgcgacta atcttgatga aatctatgta aacagccgta
    20341 gccaaggttt tggtgaagaa gtgaagcgcc gtatcatgct gggtactttc agtctttcat
    20401 caggttacta cgatgcctac tacaagaagg ctggacaggt ccgtacactt atcattcaag
    20461 atttcgaaaa agtcttcgcg gattacgatt tgattttggg tccaactgct ccaagtgttg
    20521 cctatgactt ggattctctc aaccatgacc cagttgccat gtacttagcc gacctcttga
    20581 ccatacctgt aaacttggca ggactgcctg gaatttcgat tcctgctgga ttctctcaag
    20641 gtctacctgt cggactccaa ttgattggtc ccaagtactc tgaggaaacc atttaccaag
    20701 ctgctgctgc ttttgaagca acaacagact accacaaaca acaacccgtg atttttggag
    20761 gtgacaacta atgaactttg aaacagtcat cggacttgaa gtccacgtag agctcaacac
    20821 caattcaaaa atcttctcac ctacttctgc ccactttgga aatgaccaaa atgccaacac
    20881 taacgtgatt gactggtctt tcccaggagt tctaccagtt ctcaataaag gggttgttga
    20941 tgccggtatc aaggctgctc ttgccctcaa catggacctc cacaaaaaaa tgcactttga
    21001 ccgcaagaac tacttctacc ctgataatcc caaagcctac caaatttctc agtttgatga
    21061 gccaatcggt tataacggct ggattgaagt cgagctagaa gacggtacga ccaagaaaat
    21121 cggtatcgaa cgtgcccacc tagaggaaga cgctggtaaa aacacccacg gtacagacgg
    21181 ctactcttac gttgacctta accgccaagg ggtacctttg attgagattg tatctgaagc
    21241 cgatatgcgt tcgccagagg aggcctatgc ttatctgaca gccctcaagg aagttatcca
    21301 gtacgctggc atttctgacg ttaagatgga agaaggttct atgcgtgtgg atgccaacat
    21361 ctcccttcgc ccttatggtc aagaaaaatt cggtaccaag actgaattga agaacctcaa
    21421 ctccttctca aacgttcgta aaggtcttga atacgaagtc caacgccagg ctgaaattct
    21481 tcgctcaggt ggtcaaatcc gccaagaaac acgccgttac gatgaagcta acaaaacaac
    21541 catcctcatg cgtgtcaagg aaggggctgc tgactaccgc tacttcccag aaccagacct
    21601 acccctcttt gaaatttctg acgagtggat tgaggaaatg cggactgagt tgccagagtt
    21661 tccaaaagaa cgtcgtgcgc gttatgtatc tgaccttggt ttatcagact acgatgctag
    21721 tcagttgact gctaataaag tcacttctga cttctttgaa aaagctgttg ccctaggtgg
    21781 tgatgccaaa caagtctcta actggctcca aggggaagtc gctcagttct tgaatgctga
    21841 aggtaaaaca ctggaacaaa tcgaattgac accagaaaac ttggttgaaa tgattgccat
    21901 catcgaagac ggtactattt catctaagat tgccaagaaa gtctttgtcc atctagctaa
    21961 aaatggcggt ggcgcgcgtg aatacgtgga aaaagcaggt atggttcaaa tttcagatcc
    22021 agctatcttg atcccaatca tccaccaagt ctttgccgat aacgaagctg ctgttgccga
    22081 cttcaagtca ggcaaacgta acgccgacaa ggcctttaca ggattcctta tgaaggcaac
    22141 caaaggccaa gccaacccac aagttgccct taaactactt gcacaggaat tggcgaagtt
    22201 gaaagaaaac tagacagaac aaaaccagcc ctaaggttgg ttttttcttc tctaccaact
    22261 cccaataact attttggctt tatttccaga gtattttatg gtaaaatgaa gagtaataat
    22321 atttattaaa gaggtaaaaa catgattgaa gcaagtaaat taaaagctgg tatgaccttt
    22381 gaaacagctg acggcaaatt gattcgcgtt ttggaagcta gtcaccacaa gccaggtaaa
    22441 ggaaacacga tcatgcgtat gaaattgcgt gatgtccgta ctggttctac atttgacaca
    22501 agctaccgtc cagaggaaaa atttgaacaa gctattatcg agactgtccc agctcaatac
    22561 ttgtacaaaa tggatgacac agcatacttc atgaatacag aaacttacga ccagtacgaa
    22621 atccctgtag tcaatgttga aaacgaattg ctttacatcc ttgaaaactc tgatgtgaaa
    22681 atccaattct acggaactga agtgatcggt gtcaccgttc ctactactgt tgagttgaca
    22741 gttgctgaaa ctcaaccatc tatcaaaggt gctactgtta caggttctgg caaaccagca
    22801 acgatggaaa ctggacttgt cgtaaacgtt ccagacttca tcgaagcagg acaaaaactc
    22861 gttatcaaca ctgcagaagg aacttacgtt tctcgtgcct aatctctaga aagaggtcat
    22921 tctatgggaa ttgaagaaca acttggcgaa atcgttatcg ccccacgtgt acttgaaaaa
    22981 atcattgcta tcgctactgc aaaggtagag ggtgttcact ctttttcaaa cagatcagtg
    23041 tctgataccc tttcaaaact ttcactcggc cgtggcattt atcttaaaaa cgtggacgaa
    23101 gaactcacag cagatatcta tctctacctt gagtacggag taaaagttcc taaggtagcg
    23161 gttgctatcc agaaagctgt caaagatgcc gtccgtaata tggctgatgt agaactcgct
    23221 gctatcaata ttcacgttgc aggtatcgtc ccagataaaa caccaaaacc agaattgaaa
    23281 gatctatttg acgaggactt cctcaatgac tagtccacta ttagaatcta gacgccaact
    23341 ccgtaaatgc gcttttcaag ctctcatgag ccttgagttc ggtacggatg tcgaaactgc
    23401 ttgtcgtttc gcctatactc atgatcgtga atatacggat gtacaacttc cagccttttt
    23461 gatagacctc gtttctggtg ttcaagctaa aaaggaagaa ctagataagc aaatcactca
    23521 gcatttaaaa gcaggttgga ccattgaacg cttaacgctc gtggagagaa acctccttcg
    23581 cttgggagtc tttgaaatca cttcatttga cactcctcag ctggttgcta ttaatgaagc
    23641 tatcgagctt gcaaaggact tctccgatca aaaatctgcc cgttttatca atggactgct
    23701 cagccagttt gtaacagaag aacaataaaa agaaaaagtg tttgatagat atcaaacact
    23761 tttttctttg cctcccacta tctaaaaaaa tgataataga tataattgta aacaaaaatc
    23821 cagataggtt ttgcatgatt gagaaagtta aaaaaactat ggcagagaat cgttaatctc
    23881 agattgtcgg tagaacgata aacaagggca aaaaagaaac caatcagact ataatataat
    23941 aaactaattg gatctctgtg agatagtatc aaatggctaa tcccaaagat aaggcctgat
    24001 aagatgacat ctaaatagta ctttgactta ggaaagaagg tattcataaa ataccctcta
    24061 tcaagagtct cctcaaaaac aggaccgatg attacaagca ggacaaaaga taagatagtc
    24121 gataaaaagg ttggttgtcc atttgaaaga accacggtaa aatactcatc atgaatattc
    24181 ctatggttaa tcaaatgagc atagcgtgcc taaaaattac cgagaatctg ataaaccaca
    24241 tacgttgcaa ataagtagaa gacaaatgac cagttccagc tctttttttc aaagataaag
    24301 agcatctttt tcttttttaa cctccaaatt aatagaagga aacttcccac taataccatt
    24361 gttaaaataa gagaatagac atcagctcct aaccctaaaa tgatcgtcac atacaatcca
    24421 attgtttgtg gtaaataggt agatagtaaa ataataagca aaaatattcc aaattgtctt
    24481 agtttttttg tgtttctcat cgtacttttt tgaaagatta ccctgctcgg aagccgtact
    24541 tccaagcatc tatataagaa ttaagtgccc cttgcctcat ataaggagca aattctctat
    24601 aatataacca tctactatat ccatcttccc aaacagcaag accacctgaa gtttgctcca
    24661 agtcctcagt tgaaataact gtaaatgttt ctgtagctgt cattgcaagt accttcttaa
    24721 aatatagtg
//
LOCUS       DAVKZI010000032        24445 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKZI010000032 DAVKZI010000000
VERSION     DAVKZI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.033"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(190..393)
                     /locus_tag="VXB18_001506"
     CDS             complement(190..393)
                     /locus_tag="VXB18_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pncT"
                     /protein_id="HEV0382689.1"
                     /translation="MEKIDYITLNEVELETISGGDDCFIGDIGCIGWGLLKSIGGMIK
                     PAPYVPPVCIPKSSWNPAPPVPC"
     gene            complement(711..914)
                     /locus_tag="VXB18_001507"
     CDS             complement(711..914)
                     /locus_tag="VXB18_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEV0382690.1"
                     /translation="MNTKMMEQFSVMDNEMLDRIEGGIFGVDDALFWAGLGYVAGSIV
                     DTAIDDFTNQCRKNPHQWFCVRV"
     gene            1195..3348
                     /gene="blpA"
                     /locus_tag="VXB18_001508"
     CDS             1195..3348
                     /gene="blpA"
                     /locus_tag="VXB18_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEV0382691.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3359..4720
                     /locus_tag="VXB18_001509"
     CDS             3359..4720
                     /locus_tag="VXB18_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0382692.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4777..4932
                     /gene="blpC"
                     /locus_tag="VXB18_001510"
     CDS             4777..4932
                     /gene="blpC"
                     /locus_tag="VXB18_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0382693.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(4976..6316)
                     /locus_tag="VXB18_001511"
     CDS             complement(4976..6316)
                     /locus_tag="VXB18_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0382694.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6330..7067)
                     /locus_tag="VXB18_001512"
     CDS             complement(6330..7067)
                     /locus_tag="VXB18_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382695.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRFLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7072..7410)
                     /locus_tag="VXB18_001513"
     CDS             complement(7072..7410)
                     /locus_tag="VXB18_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382696.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7687..8016
                     /locus_tag="VXB18_001514"
     CDS             7687..8016
                     /locus_tag="VXB18_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0382697.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8184..9233)
                     /locus_tag="VXB18_001515"
     CDS             complement(8184..9233)
                     /locus_tag="VXB18_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382698.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LGWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9230..9961)
                     /locus_tag="VXB18_001516"
     CDS             complement(9230..9961)
                     /locus_tag="VXB18_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382699.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10029..10439
                     /locus_tag="VXB18_001517"
     CDS             10029..10439
                     /locus_tag="VXB18_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0382700.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10449..10736
                     /locus_tag="VXB18_001518"
     CDS             10449..10736
                     /locus_tag="VXB18_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382701.1"
                     /translation="MKLSNLLLFAGAATGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10898..11074
                     /locus_tag="VXB18_001519"
     CDS             10898..11074
                     /locus_tag="VXB18_001519"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382702.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTHIYTTRQR"
     gene            complement(11103..12239)
                     /gene="dnaJ"
                     /locus_tag="VXB18_001520"
     CDS             complement(11103..12239)
                     /gene="dnaJ"
                     /locus_tag="VXB18_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0382703.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGGLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12641..12997)
                     /locus_tag="VXB18_001521"
     CDS             complement(12641..12997)
                     /locus_tag="VXB18_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0382704.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12999..14822)
                     /gene="dnaK"
                     /locus_tag="VXB18_001522"
     CDS             complement(12999..14822)
                     /gene="dnaK"
                     /locus_tag="VXB18_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0382705.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAESDKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15302..15826)
                     /gene="grpE"
                     /locus_tag="VXB18_001523"
     CDS             complement(15302..15826)
                     /gene="grpE"
                     /locus_tag="VXB18_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0382706.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15853..16887)
                     /gene="hrcA"
                     /locus_tag="VXB18_001524"
     CDS             complement(15853..16887)
                     /gene="hrcA"
                     /locus_tag="VXB18_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0382707.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17051..17560)
                     /locus_tag="VXB18_001525"
     CDS             complement(17051..17560)
                     /locus_tag="VXB18_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0382708.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18167..20500
                     /locus_tag="VXB18_001526"
     CDS             18167..20500
                     /locus_tag="VXB18_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0382709.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVGEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20513..21976
                     /locus_tag="VXB18_001527"
     CDS             20513..21976
                     /locus_tag="VXB18_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0382710.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21976..23544
                     /locus_tag="VXB18_001528"
     CDS             21976..23544
                     /locus_tag="VXB18_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0382711.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFVDGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            23601..24398
                     /gene="psrA"
                     /locus_tag="VXB18_001529"
     CDS             23601..24398
                     /gene="psrA"
                     /locus_tag="VXB18_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0382712.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT         7868 a         4835 c         4452 g         7290 t
ORIGIN      
        1 atttgaagca gtattagctg gttagaaagt gaatttttaa cgttccaacc agccattagt
       61 ttctagtttt cgactcttgc aataagctaa aataatcctg aacaacacct gtatattata
      121 gttgcgaaga ttcaacaaaa tagcgaacaa gtcgattatt cattttttat ataagtttac
      181 aataactttt taacatggaa ctggaggtgc aggattccac gaactttttg gaatgcatac
      241 tggaggaaca tatggagcag gttttatcat ccctccgata ctcttcaaaa gcccccagcc
      301 gatacatccg atatctccaa taaaacagtc atctccacca ctaatcgtct ctaattctac
      361 ttcattcaaa gtaatataat caattttttc cattgttata attcattcct ttcgttttac
      421 tcaaggcaca acacagaatg aaaaagtgtt gtactcttta ttttataatg tttataataa
      481 tagtgagaaa acctatcact actacaaatc acggggaggt gaataagtga gtgatatagc
      541 caatatctcg catttttata ggtgtcattc tttctatcaa gcacaagaac tgtgactagg
      601 agcacgtaaa cttataacag aataagcgac tcgtttgcaa aagaatagtt tctatcactg
      661 cataggtcat taagttatat aaattcttat acaatacaac actactatat ctatacacga
      721 acacagaacc actgatgagg atttttccgg cattgattcg taaaatcatc aattgctgta
      781 tcaacaatgc tacctgcaac atagcctaac cctgcccaaa acaaagcatc gtcaactcca
      841 aatattcctc cctctatcct atcaagcatt tcattatcca taacagaaaa ttgttccatc
      901 atttttgtat tcatgacaaa tactcctttt ttatttttaa tttttgtctt gttgcaactt
      961 tgacaagttt agtatatcat tattttttaa tttttttcat ccaaatcttg aattggcatc
     1021 gaaacgtctt gaattagctt ttttatttca agccacctct aaatgtttaa aaaaaataat
     1081 ttctaatcac ttttttacca ttcaggaagt tttaatgact attcaagatt tcataaaata
     1141 tgaacttagt tttatggcat aatataccta tccactatat gaaaggaatt gccaatgact
     1201 tcttataaac gtacatttgt tcctcaaata gatgcgagag actgtggtgt cgctgcctta
     1261 gcctcgattg ctaaattcta tggttcagat ttttctctag ctcacttgag agaacttgca
     1321 aagaccaata aagaagggac gactgctctt ggcattgtaa aagccgctga tgaaatgggc
     1381 tttgaaacaa ggcctgttca agcagataaa actctctttg acatgagtga tgtcccctat
     1441 ccatttatcg ttcatgttaa caaagaagga aaactccaac attactatgt tgtctatcaa
     1501 acaaagaaag actatctgat tattggtgat cctgaccctt ctgtaaaaat cactaaaatg
     1561 tcaaaagaac gctttttctc tgaatggact ggagtagcta tttttctagc tcccaaaccc
     1621 agctatcaac cccataaaga taaaaagaat ggtctactaa gcttccttcc tctgattttc
     1681 aaacaaaaat ctctcattgc ttacattgtt ctctcaagct tattggtcac tattatcaat
     1741 atcggtggtt cttattatct ccaaggaatc ttggatgaat acatcccaaa tcagatgaaa
     1801 tcaactttag gaatcatctc agttggtctg gttatcacct atatcctcca acaagtcatg
     1861 agcttttcca gagattatct cctaaccgtt ctgagccaga gattaagcat tgatgtgatt
     1921 ttatcctata ttcgccatat ttttgaactt cccatgtctt tctttgcgac acgtcgtaca
     1981 ggagaaatca tttcacggtt cacagatgct aactctatta tagatgcctt ggcttctacc
     2041 attctttctc tttttctgga tgtttctatt ctgattcttg tagggggcgt cttactggca
     2101 caaaacccta atctcttcct cctttctctt ctttccattc ctatatacat gttcatcatc
     2161 ttttctttta tgaaaccttt cgaaaaaatg aaccatgatg tcatgcaaag taattctatg
     2221 gttagctctg ccattatcga agatatcaac gggattgaaa ctataaagtc gctcacgagt
     2281 gaagaaaatc gctatcaaaa tatagacagc gaatttgtag attatttgga aaaatccttt
     2341 aagctcagta aatattctat tttacaaacg agtttaaagc agggaacaaa attagttctg
     2401 aatatcctta tcctatggtt tggcgctcaa ttagtcatgt cgagtaaaat ttctatcggt
     2461 cagctgatta cctttaacac acttttttct tactttacaa ctcctatgga aaatattatc
     2521 aacctccaaa ccaaactcca atctgcgaag gtcgctaata accgtttgaa cgaagtctat
     2581 ctagtcgaat ctgaatttca agttcaagaa aaccctgttc attcacattt tttgatgggc
     2641 gatattgaat ttgatgacct ttcttataag tatggttttg gacgagatac cttaacagat
     2701 attaatctca cgattaaaca aggagataag gttagcctag ttggagttag tggttctggt
     2761 aaaacaactt tagccaaaat gattgtcaat ttctttgaac cctacaaagg gcatatttcc
     2821 atcaattatc aggatattaa aaacattgat aaaaaagtct tgcgccgtca tattaattac
     2881 ctaccccaac aagcctatat ctttaatggc tctatcttgg aaaatttaac cttgggcggt
     2941 aatcatatga ttagccaaga agatattcta agagcttgtg aattagctga aatccgtcaa
     3001 gacattgaaa gaatgcctat gggctatcaa actcagctct ctgatggagc tggtctatca
     3061 ggaggacaaa agcaacgaat cgctctcgct cgtgctcttt taactaaagc tcctgtttta
     3121 atactagatg aagctactag cggtcttgat gtcttgactg agaaaaaggt tatagataat
     3181 cttatatccc taactgataa aaccattctc tttgtagccc atcgtctcag tatagccgaa
     3241 cgaactaacc gtgtcattgt tcttgaccag gggaaaatca ttgaagttgg tagtcaccaa
     3301 gagttaatgc aggcgcaagg cttctaccat catctattca ataaataagg agaatgtcat
     3361 gaatcctaat ctttttagaa gtgtcgagtt ttatcagaga cgttaccata actatgcgac
     3421 agtgttcatt atacctcttt cattactatt tactttcatc ttgattttct cccttgttgc
     3481 cacaaaagaa attactgtta cttcccaagg agaaatcgcc cctacaagtg tcattgcatc
     3541 tattcagtcg accagtgata atcctatcct tgctaatcat ttagtggcaa atcaagtagt
     3601 tgagaaaggt gacttactca tcaaatactc tgaaacaatg gaagaaagtc agaaaactgc
     3661 cttagcaact caattacaaa gacttgagaa gcaaaaagaa ggacttggaa tcttgaaaca
     3721 aagcttagaa aaagcgactg atcttttttc tagcgaggat gagtttggct accataatac
     3781 ctttatgaat tttactaaac aatcccatga tattgaactg ggtatctcaa agactaacac
     3841 tgaagtttca aatcaagcta atcttaccaa tagcagttca tcagccatcg aacaagaaat
     3901 tacaaaagtt caacaacaaa ttggagaata tcaagagttg agagatgcta tcataaataa
     3961 cagagcacgc ttaccaactg gcaatccgca ccagtcaatt ttaaatcgtt atcttatagc
     4021 ctctcaagga caaacacaag gaacggcaga ggagccattt ttatctcaaa ttaatcaaag
     4081 tattgcaggt ctggaatcat ctatcgcaag cctcaaaatt cagcaagctg gtatcggaag
     4141 tgtagcaact tatgataata gtttagcaac caaaattgaa gtactccgca ctcagttttt
     4201 acaaacagcc tcacagcaac aactaaccgt ggagaatcaa ttaacagaat taaaagtaca
     4261 actagatcaa gcgacacagc gcttagaaaa taatacctta accgctccaa gtaaaggtat
     4321 cgttcatctg aacagcgaat ttgaaggtaa aaatagaatt ccaactggta cagaaattgc
     4381 tcaaatattc cctgtcatca cagatacaag agaagtacta atcacttact acgtatcatc
     4441 tgactatctc cccttactag ataaaggaca aactgtaaga ttaaaactgg agaagattgg
     4501 aaatcacggc accaccatca tcggccaact tcagagtatt gatcaaactc ctaccagaac
     4561 agagcaaggc aatctcttta aattaaccgc tcttgcaaaa ctatctaacg aggatagtaa
     4621 actcatccaa tatggcttac aaggtcgcgt cactagtgta actacaaaga aaacatattt
     4681 tgattatttc aaagataaaa ttttaaccca ttctgattaa ttttcagata acactctata
     4741 actatttatt atcttatcaa aaaggagaat cataacatgg ataagaaaca aaacctaact
     4801 tcatttcaag aactaacaac taccgaactc aaccaaatta taggtggagg atggtgggaa
     4861 gatttcttat atagatttaa tataattgaa caaaaaaata caaaaggatt ttatcagcca
     4921 atacaactat aaaaaaacaa gaccaagaga acgcactctc ggtcttattt tttcttcatt
     4981 ctatatgtat tacagtaagt acctgacgaa aaacgtgatc ttggcaggtg gtattgagac
     5041 tggtattggg atgactttcc acaattttca taacggtata gagaccaact cctctctcct
     5101 cccctttaga acttgctcca aaggagaaga tttcagaaat atcgattccc tcttctttga
     5161 tggaattttc aatgataaag gtctcctgtg ctccattttt aaaaaaggca attgaaacat
     5221 gaggttgaca ggcttctaca ctagcttcaa tagcgttgtc acaaaggata gacacaacgg
     5281 ttagaaaatc aagtagactc accccctcta cctgaatctc ctctggaact tcgacattaa
     5341 agacaatgtt cttatctcta gcttttataa attttccagc taggagactt ttgagggcac
     5401 gatcccgaac attcaccaat cggccaaggt catatttatt gtcctgcaat ttttcactag
     5461 aatcctttaa gaccgagtcg tagatctctt ttatctgctc catatcctcc tcttcaatgc
     5521 ccagacgtaa gctagtcaag aggttggtgt agtcatggcg aaaactccgt acttccttat
     5581 aaagctcctc tatatgccga ctataccgct ccatctctct gtagcgcaag tcctgctctt
     5641 ggttcagtct ctcatggagt ttgtccttca aataggtatc caatttcttg ataatcccca
     5701 taaaaaagag caggtaaaag actaggatga gatggcgaac agtcgttgat tgaatcccct
     5761 gttcatattc aaagtaagac agattttgta tcaccaaata gtaagccccc attatccagt
     5821 taatctgagt cagggacttt tgaaaatctt tatcgagaat cccctttctc aagctagtga
     5881 aatcatagtc caaccatttc aaaaaagcta gagaaatgaa gaaattgaaa attattatac
     5941 ataaccaaat aaatgagtag tcatcatata cttgcccttg tcccaaaaat ggaagcacaa
     6001 aataggaaac acctctataa aagagattca ctaatatcat tggaaagaga ccataaaaga
     6061 gaaggagttt tttaggaagt tctcttaaca ataagaaaga taagcctatg ccgtacaagg
     6121 gttccataaa ataagatagg taaacatttc ctaccatata gccaagcatt ccaaaaacaa
     6181 cggccaacag tatcttaaaa agaaaggcct taaaaatcct ctcaaaagtg agactaattc
     6241 catctacctt aaagaatatg acaattttta atccgtgagt aacaagtgta tacaacaata
     6301 tccaagcaac attcataaac tctcctagct cagtgtaagt tattaatagc ctcagacact
     6361 tccctgacct tataacgcgc gattagacaa cttccaccat tgggaaagaa aagcagtttt
     6421 tctttcttat ctaaatgcac cacattggca ggattgatga gaaaagagcg atggcactgc
     6481 aagaaacgag gctcctgctt gagaacctcc tctagactcg ctgtaaattc cagcctgtct
     6541 gtcttggtat agagaataac acgatggggt cttgtggacg tttcgagata gtaaacctct
     6601 ttaaaaggat actggaattg agcaaatttt gatttaaagt aaaagcaatc ttccgctaga
     6661 cttttactgt cttgaccatt ggcatagagg agggctgtct cgatacgaga ttcaaactcc
     6721 tctgccgaaa gggccttatc aatataatcc agagcagaca cttggtagcg aaaggacagg
     6781 ggcataaact ccgagtgagt cgtcacaaag acaatcaggg catacggatc ccgatcccga
     6841 atctttctag ccacttccag acccttcatc tcctcatttc gaatctcaat atccaaaaag
     6901 aatagctgat gggccccctt ctcatgcacc tctgccagca attgatctgg cttaccaaaa
     6961 acttcaaaag aactcagagt gatatgatgt tccttcaaga gtttctcaat cgtcgtttca
     7021 attctagtct gttgggaaaa atcatcttct aaaacaaata ttctcatctt cttactctcc
     7081 ttctttcaac catttttgac gaatttctct atagcgacgt ctggcatact tgacagcgta
     7141 ttgaccttct tctccaagaa aaaggattct ttcttgaaaa tcaatcgatt ttactttatc
     7201 aagattgacc aaacaatttc gatgacatct catcaaggtt tccccatatt ggttctcaag
     7261 attacttaaa ttttgaacca tattaaaact agcctcttct gtaacaatct ttacagtatg
     7321 ggctttagtt ggatgtgttt ggatatagta gacatcgtcg acgtttactt tatagactgt
     7381 tttctgtgtc tgaataatca tatgtttcat tggattctcc tcctaagaaa agaataacag
     7441 aaaaaatcta acacaagcac acccaatcct aaacagtctt tgaaagctcc taaaagaatt
     7501 atttttctac aatatcatga tgagcttacc actattttat cataaaattc actcagcgca
     7561 attcaagaca tttcaatgac aattaaagat ttaaaggcga aaaaggagat aaaagtgata
     7621 gactgacagt atcaaaacac agttgctaga atcaagactg gcacccagat tagaggagga
     7681 attctcatga cagatacaga ccctatcaaa agagctcaga ctttgattac tgacttaaac
     7741 aaagcctatc aagcatgcaa acaggcaacc gctgacgacg tccgctttca ggagcaatta
     7801 aactctattc ttggttttct agccaaggct gaaacagtgg ataatcgatt cttgattgaa
     7861 ttggaaaaat tttaccagac ttccagtctt ctcatgggac tcagcgctct tgatccagat
     7921 gctccaactc gcgccgcttg gcgggcctat gaccgcttcc actttgacca agtcaagacc
     7981 aagttaatac tcaatgagaa tcaaagagca aactaggaag ctagccgcaa gctgtacttg
     8041 agtacggtaa gacgacgctg acgtggtttg aagagatttt cgaagagtat aagtctctac
     8101 ggaccaacca ttatcctgta gtaacaaaaa agaagttgag acagactgaa ctcaacttct
     8161 tttttagtgt cgtatcagca atgttagtcc tgcatctgac gttttacctg ataaggcaaa
     8221 tacaagacta gtaaaaccaa accagctcct agtaaggcta gaagggctag tttttcttgg
     8281 aaggtaatca acccaacaac tacttccaca agtaaaacaa aactggtcaa tcctcgaact
     8341 acctcctgta agcctttttc cttttgcccc ttgtccagcg gaaagagttg ggtcaaatac
     8401 tggtagtcaa aggcatgata gagggccagc aactggaaga gcaagaggta gttaaagaga
     8461 actaccactg ctgtcgcaat ccaagcttgc tcgataaaaa cctgcgccag tacggaaagt
     8521 aagagaagac gaagactgag agcaaagagg tcgccatttc gcagataaga acgcagatag
     8581 agattttgcc aaatcttccc aggcaccttc tgaacagcct ttaagataaa gtccagatag
     8641 gcacgacgct tgacactgtt tgaaattccc ttgacctgcg taaagagggc aaagaaacga
     8701 agcaagactt gcttacgctt gctttcttga gaaataagat agtcccagcc cagtccagtt
     8761 tcagtgaaaa atttgctggc cttttgacga aagtggaaat attttcctac ccccaataaa
     8821 agcacataga gcagaaaaac tggcaagcca taacccattg ctaaaaacaa gggcgcaaat
     8881 aacagcaaga aaagggtctg tacaaagagc caaaagacta gggaaatgcc agtttgacgc
     8941 ttgagatgga gcttgatttc ctcttctcca actaagagaa agagcttgtc tggagcctcc
     9001 atataggtgg caattcctcc ccaaagtaaa agtaaaacag acgtaattcc tacaaacaaa
     9061 aggataggcc aatgattttc aggaaaatgt tgtaagagtt gactgtactg gtaggctaga
     9121 aagcccaaca ggacaagcag gaacaagaca aagtggtcat tgagcacata gcgcagataa
     9181 ccaagacact ccttacgaaa ggcctgcttt ctctttaaaa acaagtcttt catagatcct
     9241 cctctttggt cagagccaag taaatatcat tcaaactagc ctcaggcata tcaaaggctt
     9301 cacgtagttg caggagattg cctttggcac gcacctctcc cttgtgaaga atgacaaagg
     9361 catcacacat cttctccgcc gaatccagca cgtgggtact catgagaata gacttgccct
     9421 tttgcttctc cacttccaaa agctgaatca aatcagaaat agccagcgga tcaagaccaa
     9481 ggaaaggctc atccacgatg aaaagacttg gatccaccac aaaagcacag ataatcatga
     9541 ccttctgctt catccctttt gaaaaatgaa cagggaacca gtctaatttc tgttccaaac
     9601 ggaacatttt taacaagggc tctactcgtt cgaaagccac tttttgctca ataccgtaag
     9661 ccatagcaac cgtttcgata tgctctctga gggtcaattc ctcatacaga ctaggcgtct
     9721 caggaatgta gccaatctgc ttgcggtagc tagtcgcatc tccttgcaga gtcaggccat
     9781 tgatattgat ggagccacta taaggtgcca acagaccgat aatctcattg atcgtcgttg
     9841 atttcccagc accattgaga ccaatcaaac cgaccaactg cccactttca acagtaaagg
     9901 acacatcttt caaaacagga acatgaacat agccacctgt caggttttta atttctaaca
     9961 tattttctcc aaatctggta taatgtagct atattatatc aaaattcagt acagtagagg
    10021 tagattttat gtcagattgc attttttgta aaatcatcgc aggggaaatt cctgcttcaa
    10081 aagtatatga agatgagcag gtccttgcct ttcttgatat ctctcaagta acactaggac
    10141 acaccttggt cgtgccaaaa gaacactatc gcaatctttt ggagatgaat gctacgagcg
    10201 ccagccaact ctttgcccaa gtaccaaaag tagctcaaaa agtcatgaaa gtcactaagg
    10261 ctgctggtat gaatatcatt tccaactgtg aagaagtcgc tggtcaaaca gtttttcata
    10321 ctcacgttca ccttgtgcct cgctacagtg ctgacgatga cctcaagatt gattttatcg
    10381 cccacgaacc agactttgac aaacttgctc aagtcgctga aaccatcaaa aacgcttaag
    10441 gagttgctat gaaattatcc aacctactgc tatttgcagg agctgcaacc ggaagttatc
    10501 tggttacaaa aaatcgccaa accatcacag atgaagtctt gaataccact gaccgcgttc
    10561 aagctatcaa agacgatgtg gatattatcc aaaatagcct gcaaatcatc gaccagcaaa
    10621 aagaacttat caaggaatac caagaagact tgacttacaa gtttaaggtc ttggaaaagg
    10681 atatccagac tagactagct gtgataaaag aaatgcaggg aactgaagat aagtaaaaag
    10741 agccccccgg ctctttttta aaacgtaaac aagttatagt gaattgaatt tagaatagca
    10801 catcatagtt tctaaagcat tgttagagat tactttaaaa tcctcttatc aatttgttca
    10861 tattctattt caatctacta tatatatccc atcaactatg catcataatt taggtaactc
    10921 atactcaata aaaatcaaaa agcaaactag aaagctaggc acagactgct caaaacaccg
    10981 ttttaaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgtaga
    11041 tacgactcac atatatacga caaggcaacg ctgacgtggt ttgaagaaat ttttgaagag
    11101 tatcattctc catcaaaggc atctttaata tggtcaaaga agcctttttt ctttggattt
    11161 actttcaagc caccagcagc cgcgaattct ttcaaggcta ctttttggcg gtcgttcaag
    11221 cctgtcggtg ttacgacatt aacagtaacg tattggtcac caactgcacc gccacgaagg
    11281 ctcggtgccc ccttactacg taggcggaat ttcttaccag tctgagttcc ctctggaata
    11341 accaattcaa catcaccgtg aacagttgga atatctactg tatcaccaag agccgcttgg
    11401 acaaagttga ggttgagatt gtagaagata gtcgttcctt cacgttcaaa cttgtcacta
    11461 gcttccacag aaactactac atacaagtca ccataaggtc caccgttaaa gcctgcttca
    11521 ccttgaccag cgaggcgaat ttgttgacct gtttccacac cagcagggat tttcacatgt
    11581 acgctatgag cttgtttctc atgacctgtt ccatgacagg ttgtacatgg atatttgatt
    11641 tcttttcctc gaccgtgaca gacatcacag gttacttggc gacgcatcat accaagagga
    11701 gtctgcgtat cgacgttaat gacaccagcg ccatgacagc gtccacaagt gactggactt
    11761 gtccctggct tagcaccaga tccattacat gtacgacagc cagcttcacg atgatactta
    11821 acttccttct cagttccgaa gatagcttct tcaaaggtca aattgacacg atactggaga
    11881 tcatctcctt ggcgaggagc gtttggattg cgcgaagaac cgcctccgcc gaagaaactt
    11941 gagaaaatat cctcaaaacc accgaagcca cctgccccat tgaaaccgcc gaaaccacca
    12001 gctccaccaa aaccaccatt ggcgcctgca gcaccatact ggtcataggc agcacgtttt
    12061 tggtcgtcac tcaaagtctc ataggcttct tgaacttcct tgtacttgtc ctcagcacca
    12121 ggctccttgt tgatatctgg gtgatatttt ttggaaagct tacgataagc ctttttgatt
    12181 tcgtctgccg aagcgttttt ggataccccc agacgatcat aaaattcagt attgttcata
    12241 attcaagata caaagggcgt caaacggaca cagccatcta ggagttttga cgacggacgc
    12301 ttacgtccta gaaaaaacta tctttttggc acagtccgta gcccgtgttc agttacgaac
    12361 acccttattc ctttctattg atgttctgaa tcgaaccacc atttaggtcg ggttcaattc
    12421 ctttctttta tatttagtaa gaaattctga aacccgtgtt cagttacgaa cactctttgt
    12481 tcctttctat tgatgagaca aaacccaaac aaatgagatt ccgtcccttt ttatcgaaaa
    12541 acagaggctg ggttgcaacc tctgcaaata agtaaattaa ctttattttg attttaaata
    12601 tcctataagt acagaaatat ttatatattt ttgtctcttc ttagtatttg cctatataat
    12661 tccaattgat cataagaaat acaactactg tccaaatcat accaattatg aacggtatta
    12721 caaatttata tgtttgtatt tctaatgata tcatagctga taccatcgcc gatacaaatg
    12781 cagacaacaa tactgaggta acaaaattcc ttaccgcttc atcatttttg acacaactat
    12841 catgctcagc taatataatt tctctatatc tagctaaata ttctattgga atattatcaa
    12901 taaaatcttt tgatgttcta tagttatcag cttgattaca aaaatcatta taaacttttc
    12961 gtgtattttt tagatactct tcatccaata cactcatctt acttttccgt aaactctccg
    13021 tctacgacgt catcgcctgc gtttcctgtt gcttgtgcgc cttctgctcc ttcttgagct
    13081 tgttgcgctg ctgcggcttg ttcgtagagt ttaacagcaa gtccttgagc tttttcgttc
    13141 aatgcttcaa gttttgcttt catgtcgtcc aagttgttgt cttcttgagc tttcttaagg
    13201 tcatcaaggg cagcttgggc agcgtcacgt tctgcgtcga agcctttacc ttcagtttcc
    13261 ttgattgtct tttcagtcgc aaagattgct tggtccactt cattacgaag gtctacttct
    13321 tctttacgtt tcttatcgga ttcagcgttt gcttctgcat ctttcatcat gcggtcgatt
    13381 tcttcgtcag tcaaacctga gttcgattgg atgacaatag tttgttcttt ttgagttcca
    13441 aggtctttgg ccttaacaga cacgataccg ttcttgtcga tgtcaaatgt tacttcgatt
    13501 tgaggaattc cacgaggtgc agctgggata tcagtcaatt ggaagcgtcc aagagtcttg
    13561 ttatctgctg ccattgggcg ttcaccttga agaacgtgga tatcaacggc tggttggttg
    13621 tctgctgctg ttgagaagac ttgtgattta gatgttggga ttgtagtgtt gcgatcgata
    13681 agttttgtaa atactccacc cattgtttcg ataccaagtg acaatggcgt tacatcaaga
    13741 aggacaacat ccttgacatc accagtaatc acaccacctt ggatagccgc acccatagca
    13801 actacttcat cagggtttac tgatttgttt ggttctttac cagtttcagc tttaacagct
    13861 tcaacaacgg cagggatacg agttgaacca ccaacaagga taacttcgtc gatttctgac
    13921 aagctcaaac ctgcatctga aagggcttga cgaactggaa cttttgtacg ttcaacaagg
    13981 tcacgagtca aatcatcaaa tttcgcacga gttaaagtca tttccaagtg aagaggtcca
    14041 gcctcacctg cagtgataaa tggcaagctg atttgtgttg aagttacacc agaaaggtct
    14101 ttcttcgctt tttcagccgc atctttcaaa cgttgcattg ccatcttgtc agtagacaag
    14161 tcgataccgt tttctttctt gaattctgct accaagtggt caatgatttt ttggtcaaag
    14221 tcgtcaccac caagtttgtt gtcccctgca gttgacaata cgtcgaagac accgtcaccc
    14281 aattcaagga tagagacgtc gaatgtacca ccaccaaggt caaataccaa gattttttct
    14341 tctttgtcag tcttgtccaa accataagca agagctgctg cagttggttc gttaacaata
    14401 cgttctactt caagaccagc aattttacca gcgtcttttg ttgcttgacg ttgagcgtcg
    14461 ttgaagtaag ccggaactgt aataacagct ttggttactt tctcaccaag gtagtcttca
    14521 gcgtagcctt tcaagtattg aaggatcata gctgagattt cttgtggagt gtattctttt
    14581 ccatttgcag aaactttttc agaagttccc atcttagatt tgatagagat aactgtatct
    14641 gggtttgtaa ctgcttgacg ttttgcagca tcaccaacga tgatttctcc gtttttgaat
    14701 gagactacag atggagttgt gcggtttcct tctgggtttg cgatgatttt gctttcagtt
    14761 ccttcaagaa ctgcaactgc tgagtttgtt gtacctaagt caataccgat aattttagac
    14821 atgtgttttt ctccttgtta gttaattttc tatttttctt tttgatactc ttcttaagtg
    14881 gcgacgccgt cagagcttga ctttgtcaat ctctttgact aaactttgag cctaaggtct
    14941 caaaatttgc gcaaatagcg ccacagcgaa gagtatcgtc tttggttcgc ttcgctcact
    15001 attacaaagc caaacatatt ttatctttct tcatagttta ttgtcgtttc ggacaagttt
    15061 tctattatgt aaattgcgac acgaagagtc gaaatcgatt ttatttcgac gacgagttag
    15121 taaggaagct agacaaacgc catagcgact gccgttttct gacgagttgc tttagctacc
    15181 gtcagaattg ccgaatcgaa cacgccctaa gctctgagta aaaaagatag attttcttgt
    15241 gttcatcgaa cacttcgtca atctcctatt tttactgcga gctttttacg ggctttgtat
    15301 cttagttata caccactacc attgctgggc gtaggatgcg gtcatggagt ttgtagcctt
    15361 tttgaaagac ttgggcgatg gtatctactg ggtgttcatc gtctgctggg agagtttgga
    15421 tggccatatg gtagttatgg tcaaattcgc catctgctgc gatttcttca attccttctt
    15481 ctttcaaagc gtgaatcaag ctttcttgca ccatccccaa gcccttcttc acatcatctg
    15541 tcaaaccttc aactgcaagt gcacgctcaa ggttgtcaag agatggtaag attgcttttg
    15601 ccaagtcctg gctacgataa cgttgcaagt tttgacgttc ttcattggca cggcgttgga
    15661 tattttgcat ttctgcatga gcgcgaagat atttgttttc gaactcatct gcacgttcat
    15721 ttgccaagtc caactcagac ttttcaggag ttgtttcttc agctgtttcc acaacttcct
    15781 cttcttgaac ttcttctact tcttcatttt ttatatcttg ggccatgttc gcctccttta
    15841 atgatttcaa tcttaatgta cttcataatg attactgctg aggtagcggt aaaaatctgt
    15901 caacttcatg gtcaaaacac ggttgaccac attgacttga ttgattagct gttggtaatc
    15961 cagattaact ggaccgataa tggctagaat tccaactccc cgataaggaa tgaggaactt
    16021 actactaatc accgctaggt cagctaaaca ggactcttga ccgtctgcaa cacgaacatt
    16081 ttgcatctga tcctcacgca acccctcacg aatctccaag gccacctttt gcggttggtc
    16141 aaagaactga taggctgcta gattggcaaa attcaagaga ttgaccttgc ccgccatcac
    16201 aatgttttcg ttgaacattt ccttaaagat gtgttcaaag agatcgatga cattatccgt
    16261 tgttgtaaag taacgctgga taatctgcgg aatctccgtc cgaatcttgt agtgaatatc
    16321 taaaacggtg tgaccgagga aacgttcctg aatgatgctc ttcagtttca gcaaatcctc
    16381 ctgcaagaag ttccttggaa tcagaaactg actagtaacc gttcgcgact cgtctagggt
    16441 aaataccgcc aaggctgtat gttgccccaa aacaacgata tcaaaggctg tcaaacgttg
    16501 cctgctcggc tcaacatcca gtgccactac cgtacagcca ctcaggtctg ttagcaagtt
    16561 agcagcctct tgcagaatat cctccaattt gaagaattcc tgatcaaagg ctttgacaat
    16621 ctcatatacc tcattttcag ccagccggtc aaaatccagt gagtgtttca catagtactg
    16681 aaaaccagca acacttggca tccgaccgct tgaagtatga gccttctcaa gcaacccttg
    16741 tttttctagt tccgccatgt cattacgaat ggttgcactg ctagagttaa tagactcttg
    16801 caaggctttt gatccgacag gttcgtgcgt tttggtaaag atgtcaataa tcagatttaa
    16861 aatatcctgc tgacgctctg taaccatctc atcactcctc tctgtctgat caattagcac
    16921 tcaatgcatc caagtgctaa cttatgattc tattatacac ccttagaaga gaatgtcaag
    16981 acaaaaactc aaaaaattag cactctttta tcaagagtgc taaaaatcaa tctgaagacc
    17041 tagaaccttg ctattcatct actcggtatt tcctttttag tctgaaataa ccatgaatta
    17101 gataagaaat cagaaaagca tataaaacaa aaataagaaa gaaagacata gaaagatcct
    17161 ctctaaacaa actcgtacaa acaacaagac cacctaagaa agtagttgta caggaacgaa
    17221 gtctagatcg cataacttcc catttgagcc ccttactcat atagacttga tcctctggaa
    17281 gtaaatcaga agacgattta cgaagaatcg aacaagaacc tgctcctatc aattcccaac
    17341 ctctatctct aaaatcttgc agttcatgct tatatttttt aagaaatcta gaatcataga
    17401 tacggtagat gacatcgtct ggttgacatt ggtcaaaata gaacaaacca aaacgactcg
    17461 ttctatacct ccaacctttc aaatgcatct catgtaaata ttcttcttcc ttgtccaaat
    17521 caacaatagt gaaaatccga aattctactc tgctattcat tgtcttaccc caaaattaga
    17581 aaacatgcct ggcgttattt attagataat tctttccgct tttgactcaa tctccaaaaa
    17641 atataagaaa tctgaatcgc aaaaactatc aataaaaccc aatctattat gaaagtcaaa
    17701 aacacttccc aactgaaaga actacctcca gtgacaaact ttgagaaaaa cggtagtaga
    17761 gctaaaaaga gaagcaaaat aggaagcatc cgcattgtta aaatcctttt ggcataaaaa
    17821 aatctttatt taaacgaaaa tattatggca aaatttacgc cagtttttga acggctgatg
    17881 tagatatttt atactttcaa aatgtttaaa tgtgattatt tatttttgaa aaatagctca
    17941 ccagcccgac tgaaagtgct tataaatgat aataagtcgc ctgccgaaaa cagcgaaaaa
    18001 tagcggtgtt atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc
    18061 aacaatttag cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata
    18121 gtttatttta tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat
    18181 aaagtctaag aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat
    18241 tgtatccaaa ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg
    18301 tcgaattgag gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc
    18361 actgtattac caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag
    18421 cgttcgagca ggattacaac aagctattga atatggagag attttagatg ttccatttgt
    18481 ttattcttcg aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga
    18541 gctggagtta gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa
    18601 aggattgacg tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc
    18661 aatgaaaacg ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc
    18721 cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga acggggaaaa cgttcatggc
    18781 ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc
    18841 ggatagaaac atcttagtag accaaacgat ggctgaagac tttaggccat tcgaaaaggt
    18901 aatgacgaaa attacaccaa aacttttgac tgctcctgaa aaattaaatt cttttgaaat
    18961 ttatctaggg ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa
    19021 atttgacaaa gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa
    19081 ggaaaacagt aactggcgta agataattga ttatttcagt tctgcgacac agattgggat
    19141 gaccgctact cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtgagccaat
    19201 ctatacttat agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat
    19261 gagagttaat ttagatgtag atgtggatgg ttatcgtcca gaaactggaa aagttgatgc
    19321 taacggacaa ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt
    19381 cattgatgat agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa
    19441 tgcacgattt gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg
    19501 tgctgcactt gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca
    19561 agtaactggt gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc
    19621 taattttccc gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac
    19681 atgtcgtttg attgttttag actctaatat ccaatccatg actgaattta aacaaattat
    19741 tggtcgtggc acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt
    19801 tcgaaatgtt accaatttgt ttgctgaccc tgattttgat ggtgatccag tgaaggtgct
    19861 ggaaacaggt gcgaaaacag tcagtggttc tacgcccggt ttcgtaggtg aggaaggtga
    19921 cccagtagaa aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca
    19981 agtattggat gaaaacggga aactgattac cgaaagcctg accgactaca ctcgaaagaa
    20041 tatcttaggt agctacgcca ctttgaacga ttttatcaca gtttggcata cggcagataa
    20101 aaagaagctt atcttagacg aactttataa aaaaggagtt tatctagatg ctattcgaga
    20161 gtcggaggga atatcagaac aagaaatcga tgattttgat ttactcctaa aacttgccta
    20221 tggtcaaaaa gaattaacca aaacggaacg tatcaataaa ctcaaacaaa gcggatattt
    20281 atataaatat agtgaggaag cgcgtgctgt tttggaaatt ttactgaaca aatacatgga
    20341 taaaggtatt ggagaactcg aaagcattga aacattaaaa cttccagaat ttcagatata
    20401 tggtggaacc ttcaaaatca tcaatactta ttttggagat aaaaaacgat atttacaagc
    20461 aattaaagaa ttggagcaag agctatttac agtagcttaa tgaaaggaaa gtatgtcaat
    20521 tacatcattt gtaaaaagaa ttcaagatat cactcgaaac gatgctggtg ttaatggtga
    20581 tgctcaacgt attgagcaaa tgtcttggtt attattctta aaaatttatg atagccgtga
    20641 aatggtttgg gaattagaag aagacgagta tgagtcaatt atcccagagg aattaaaatg
    20701 gcgaaattgg gctcatgctc aaaatgggga acgggtattg acaggcgatg aattacttga
    20761 ttttgtcaat aacaagttat tcaaagagtt gaaagagctt gaaataactt caaatatgcc
    20821 tattcgaaaa acgattgtta aatcagcttt tgaagatgcg aacaactata tgaaaaatgg
    20881 cgtcttgtta cgccaagtca tcaatgttat tgatgaagtt gatttcaata gccctgaaga
    20941 tcgtcattcg tttaatgata tttacgaaaa aattcttaaa gatattcaaa atgctgggaa
    21001 ctcaggagaa ttttatacgc cacgtgcagc gactgatttt attgccgaag ttcttgaccc
    21061 aaaacttgga gaatcaatgg cagaccttgc ttgcggaaca ggaggcttct tgacttcgac
    21121 tctgaaccgt ttaagtagtc aacgtaaaac tagtgaagat accaaaaaat ataatacagc
    21181 tgtttttggt attgaaaaga aagcatttcc tcatctttta gcagttacaa atctgtttct
    21241 tcacgaaatt gatgacccta aaattgttca tggaaatact ttggagaaaa atgttcgtga
    21301 atatacggat gatgaaaaat ttgacattat tatgatgaat ccaccttttg gagggtcaga
    21361 attagaaaca ataaaaaata actttccagc agaattacgg agttctgaaa cagctgattt
    21421 atttatggct gtcattatgt atcgtttgaa agaaaatggt cgtgttggag ttattttacc
    21481 tgatggtttt ctatttggtg aaggtgtaaa aactcgcttg aaacaaaaac tggtagatga
    21541 gttcaactta catacgatta ttaggttgcc tcatagtgtc tttgcaccgt atacaggaat
    21601 ccatacgaac attcttttct ttgataaaac aaagaaaaca gaagaaactt ggttttatcg
    21661 tttagatatg ccagatggtt ataaaaattt ctcgaaaact aagccgatga agtcagaaca
    21721 cttcaatcct gttcgtgact ggtgggaaaa tcgtgaagag attctggaag gtaagttcta
    21781 caaatctaaa tcatttacac ctagtgaatt ggctgagttg aattataatt tagaccagtg
    21841 tggctttcca aaagaggaag aggaaatctt aaatcccttt gagttgattc agaattatca
    21901 agcggaaaga gcaactttaa atcataagat tgataatgta ttagctgata ttttgcagtt
    21961 gttggaggac aaataatgac accagaacaa cttaaagcaa gtattctcca aagagcgatg
    22021 gaagggaaat tagtgccgca aaatcccaat gacgaacctg caagtgaatt attaaagaga
    22081 attaaagctg aaaaagaaaa acttatcagt gaaggaaaaa tcaaacgaga taaaaaggaa
    22141 actgagatat ttcgtggtga tgatgggaaa cattatggga agtttgttga tggaagtact
    22201 caagaaattg atgttcctta tgatattcct gatacttggg agtgggtgag gttttctaca
    22261 ttggttgaaa ttgtcagagg tggctctcca cgaccaatca aagattatct tacttctgaa
    22321 gtagatggaa taaattggat aaaaataggt gatactgaaa agggtgaaaa gtatataaat
    22381 aatgttaaag aaaaaatcaa aaaatcaggg cttaacaaaa ctagatttgt aaaaaaaggt
    22441 acatttttgt taactaattc tatgagtttt ggtagacctt atattttgaa tgttgatggt
    22501 gcaatacacg atggatggtt ggctatttcg aactatgaaa actcattaaa taaagattac
    22561 ctattctata ttctttcatc aaatgtagtt tattctcaat ttctatctct aattagtgga
    22621 gctgttgtga aaaacttgaa tagtgataaa gttgcttcta ttcttatccc tctcccccca
    22681 ctatccgaac aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa
    22741 tatgctgaaa gttataatag actagaacag ctagataaag aatttccaga taaactaaaa
    22801 aaatctattc ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa
    22861 tcagtcgaag ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc
    22921 aagattaaaa agaaagattt ggacatttct attgtttccc aaggagatga taactcttat
    22981 tatgaggaag taccttgtga aataccagaa agttgggaat gggtgaggtt aaacgatata
    23041 acctcctaca ttcaaagagg gaagtctcca aaatattcaa atattcctat ataccctgtg
    23101 attgctcaga aatgtaatca atggtctggc ttttctattg acttagcaag atttattgat
    23161 cccgaaacag ttcatagtta ccagaaagaa agattactaa gagatggtga tttaatgtgg
    23221 aattcaacag gtctaggtac gttaggacga ttagctattt accatgaaaa taaaaatcct
    23281 tatggctggg ctgttgcaga tagccatgtt acagttataa gagtcttatc gggagttatt
    23341 aattgccatt tcatctataa ttttctttcc tctcctattg ttcagtcagt tattgaagaa
    23401 aaagcgtcgg gtagtacaaa acaaaaagaa ttattaacga aaactataaa agaatattta
    23461 atccccctcc caccccttcc tgaacaatcc agaatcgttg ataaaatcga acaatttttc
    23521 gcccatattg acgcactaat ttagtataat agttttacgt gcggtggaat ttctatcaaa
    23581 cataagatag gagttttacg ttgaaagatt ttgaattaca tttgaagaaa gctggtttag
    23641 ctgaaaatac tgtgcgttcg tacctttatg gtgttcgatt tttcttggag aattacgaac
    23701 tcaaaatgga agatttattt gaatacaaag gatatttatt agacaatttt aaacctaaaa
    23761 ctgtcaattt gcgactacaa ggagtaaata aatatctggc ttttattggt catgatgatt
    23821 tgaaattaaa atttgtcaaa gtacagcaaa aaccgttttt agaagatgtc attagccatg
    23881 ctgattacct ttttcttaaa cgtagtttga aaaaagatgg tattttaaaa tggcattttg
    23941 tcgtttggtt tttaggtgca actggggctc gtgtaagtga acttattaaa ctaaaagtag
    24001 agcatgtaga aatcggttat tttgacattt actcaaaagg tggtaaaatt cgtagactgt
    24061 acattcctaa aaaattaaga aatagttgtc ttagttggtt agaatcagaa aatcgccgaa
    24121 gtggttattt atttttgaat aaatttaacg aaccaattac agcaagagga gttgctcaac
    24181 agttaaaaaa ttatgctgat aaatacaaaa tgaatcctaa agtaatttac cctcattctt
    24241 ttaggcattt atttgctaag aattttttag cgaagtataa tgatattgcc ttgcttgcag
    24301 atttgatggg acacgaaagt atagaaacta ctcgaattta tctaaggaaa acagctactg
    24361 aacaacaaaa tattgtagat aaaattgtta attggtaaaa aataacaggt ggtcaaactg
    24421 actacctgct atttttgtga ttatg
//
LOCUS       DAVKZI010000033        23380 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKZI010000033 DAVKZI010000000
VERSION     DAVKZI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.034"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(20..961)
                     /locus_tag="VXB18_001530"
     CDS             complement(20..961)
                     /locus_tag="VXB18_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0382713.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(951..2207)
                     /locus_tag="VXB18_001531"
     CDS             complement(951..2207)
                     /locus_tag="VXB18_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0382714.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLYFQENEEEYED"
     gene            complement(2209..2871)
                     /locus_tag="VXB18_001532"
     CDS             complement(2209..2871)
                     /locus_tag="VXB18_001532"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0382715.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(2834..3490)
                     /locus_tag="VXB18_001533"
     CDS             complement(2834..3490)
                     /locus_tag="VXB18_001533"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0382716.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(3501..4379)
                     /gene="rsgA"
                     /locus_tag="VXB18_001534"
     CDS             complement(3501..4379)
                     /gene="rsgA"
                     /locus_tag="VXB18_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0382717.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(4381..5253)
                     /gene="rsmA"
                     /locus_tag="VXB18_001535"
     CDS             complement(4381..5253)
                     /gene="rsmA"
                     /locus_tag="VXB18_001535"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0382718.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQADLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(5384..5692)
                     /locus_tag="VXB18_001536"
     CDS             complement(5384..5692)
                     /locus_tag="VXB18_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382719.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(5685..6326)
                     /locus_tag="VXB18_001537"
     CDS             complement(5685..6326)
                     /locus_tag="VXB18_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382720.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(6328..8358)
                     /locus_tag="VXB18_001538"
     CDS             complement(6328..8358)
                     /locus_tag="VXB18_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0382721.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSIYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTEIGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRDLMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(8435..8731)
                     /locus_tag="VXB18_001539"
     CDS             complement(8435..8731)
                     /locus_tag="VXB18_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0382722.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(9051..9962)
                     /locus_tag="VXB18_001540"
     CDS             complement(9051..9962)
                     /locus_tag="VXB18_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382723.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYDKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGQPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(10034..10594)
                     /gene="rnmV"
                     /locus_tag="VXB18_001541"
     CDS             complement(10034..10594)
                     /gene="rnmV"
                     /locus_tag="VXB18_001541"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0382724.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(10594..11367)
                     /locus_tag="VXB18_001542"
     CDS             complement(10594..11367)
                     /locus_tag="VXB18_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0382725.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(11672..12325)
                     /locus_tag="VXB18_001543"
     CDS             complement(11672..12325)
                     /locus_tag="VXB18_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0382726.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKPETTPGGDKGGNTGNSD
                     ANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPKTT
                     SAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(12588..12722)
                     /gene="rpmH"
                     /locus_tag="VXB18_001544"
     CDS             complement(12588..12722)
                     /gene="rpmH"
                     /locus_tag="VXB18_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0382727.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(12867..14081)
                     /locus_tag="VXB18_001545"
     CDS             complement(12867..14081)
                     /locus_tag="VXB18_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0382728.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(14237..14542)
                     /locus_tag="VXB18_001546"
     CDS             complement(14237..14542)
                     /locus_tag="VXB18_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382729.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPGFIG
                     FLVFHVLYHLIYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            14704..15156
                     /locus_tag="VXB18_001547"
     CDS             14704..15156
                     /locus_tag="VXB18_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0382730.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(15191..16579)
                     /locus_tag="VXB18_001548"
     CDS             complement(15191..16579)
                     /locus_tag="VXB18_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0382731.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            16645..17607
                     /locus_tag="VXB18_001549"
     CDS             16645..17607
                     /locus_tag="VXB18_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0382732.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(17636..17929)
                     /locus_tag="VXB18_001550"
     CDS             complement(17636..17929)
                     /locus_tag="VXB18_001550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382733.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     SKHCFEVADETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDEVSNHTYGKAT"
     gene            complement(17993..19003)
                     /gene="ccpA"
                     /locus_tag="VXB18_001551"
     CDS             complement(17993..19003)
                     /gene="ccpA"
                     /locus_tag="VXB18_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0382734.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(19428..20027)
                     /locus_tag="VXB18_001552"
     CDS             complement(19428..20027)
                     /locus_tag="VXB18_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382735.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQTKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(20029..21126)
                     /locus_tag="VXB18_001553"
     CDS             complement(20029..21126)
                     /locus_tag="VXB18_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0382736.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(21126..21863)
                     /locus_tag="VXB18_001554"
     CDS             complement(21126..21863)
                     /locus_tag="VXB18_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0382737.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(21865..22749)
                     /locus_tag="VXB18_001555"
     CDS             complement(21865..22749)
                     /locus_tag="VXB18_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382738.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(22736..22930)
                     /locus_tag="VXB18_001556"
     CDS             complement(22736..22930)
                     /locus_tag="VXB18_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382739.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(22927..23133)
                     /locus_tag="VXB18_001557"
     CDS             complement(22927..23133)
                     /locus_tag="VXB18_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382740.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         6754 a         5432 c         4309 g         6885 t
ORIGIN      
        1 gctcattttt cttaaattat caatctaaat ctggtttata gaaggaacga ttatccatag
       61 cgaagatttt attggacatc tctcctttat ccaccaaagc cagagctgtt gacatcatca
      121 tcatacttgc atccagattg tcaatcatat ggataatctc tgcctccata atacgtggac
      181 ggactggact tccatattca agcaagccgt ggtgactgag gatgacatga cgaagcaaaa
      241 cgacttcttc cttggtatca tcgatgccga gttccataac tgtcttggta atttcgctat
      301 caatgagagc gatatgtcca agaagattac ctcgcactgt gtactctgtc tggtctggcc
      361 ccgtcaactc gataacctta gctaagtcat gcagcataat ccccgcatag agtaagctct
      421 tattgagctg aggataaact tcgctaatag cgtctgccaa acgtaccatg gtcgccgtat
      481 gataagccaa gcccgtttca aaggcatggt ggttggtctt ggcggctgga taggagtaga
      541 attccttatc atacttggtg tagagatttc ggacaatccg ttgccagaca ggattttcaa
      601 ttttgaaaat catttgcgac atgtagtcac gaatttcctt gacatcaact ggtgacttga
      661 ccttgaaatc agctgggtca ttgggttcac cagcttgagg caggcggaga gtaatttgat
      721 tgacttgagg ggtattgtta taaacttctc ggcgtccttt catgtggaca accttacctg
      781 cggtaaaggc ctcaatgtta tgaggttggg catcccagag cttcccatca atctcgccac
      841 tatcatcttg gaaggtaaag gctaggtagt ttttcccagc tcgagtttgc ctcaggtcag
      901 ctgatttgat taggtaaaag ccttcaaata actcatcttt tttcatgtga ctaatcttca
      961 tattcttcct cattttcttg aaaatagagt agatcaagcg caggctcacc ttctgacaac
     1021 tcaatgtgac ggagcgtccg ctcgatagct atggtacgac ggtttaataa ttcatcaata
     1081 ttgccagagg catgttggag atgtttttgt gccttgacca gaataccacc aaacttgcca
     1141 aactcggtct tgacactggc aagagtcttg ctgatatggt cggcactctt ttggatatta
     1201 agggtcttga aaccaactga tagggagtta agaagggctg atagggtact tggtcctgca
     1261 acaataatct gttcttcccg tctcaaatca tcaaagaaga ccggattgcg cacaatctct
     1321 gaataaagac cttctgtcgg aacaaacaag attccaaagt tggttgtccg aggcggtgct
     1381 atgtacttgc tcttgatatc cttggcaaag cgcttgacgc ttgctaggag tgacttacga
     1441 cagcgttcaa tctcatcctt gtcacctgtc tcataggctt cttccaagcg gtaataatct
     1501 gccagtggaa acttagagtc aattggaaga tagacgtatt cttggtcgcc ttgtccgggt
     1561 aacttgatgg catactccac tcgttcacta gagttttcaa ccgttgcgta ttctcgttcg
     1621 tactgggcag gtgtcatgat gtcttcaata atttgcccca gttgcaattc tcccagaatc
     1681 cctcgcgtct tggttccaga gagaaccttg ttaagagctc cgacatcacg ggcaactgtc
     1741 tgcatttctc caagaccacg attgacagac tccagttgtt tagaaactgt ctcaaaggaa
     1801 gcctgtaagc gtgtctgcaa ggtcttttct agtttttcct cgaccgtctg gcgcatttgt
     1861 tccaaacgtt gctcatttga ttcctgcaag gcttggagac gttggtctgt cttatctcta
     1921 gtttggagga gattatctgt catttcttga cggacttggg tcaggccttg gtgcaattca
     1981 atccgcactt cttgcaaacg gtcgctgaca gccacttcca aatctttttg gtctaactgg
     2041 ctggcttgtc tggcttggtc aaagcggtaa tccaactggt ctgacaaatg atctgcctga
     2101 tcctccaagc tcttacttaa gtgtttctcc tgcctatcct gcctttgcca aatcagaaag
     2161 agaccagcta ggttggcaat taataataga ataagtaaac tttccatcct acctcctatc
     2221 cttgctatgc agtacgacca cataaccatc tgggcaagtt accgacactt ccctatctat
     2281 atattcgtta gaagcgtaca cttttttaaa gaaaaaattt tcctctgtca actcatactt
     2341 ggctccaaga atagtcagct ggctatcccg aactggcata aaggctagat agtcgtagtc
     2401 tgaacgaggt tctagctgac tggtcccttc tggacaataa gtaatcaagt tttgcccatc
     2461 ctcaatttct atttgatgca tatagggtgc caacttagga ttgctaggca gaaagacatt
     2521 ggccaacata tggtcaatac ggccacccaa ggcaccgaaa atagtaacct gagcctgagg
     2581 atttttctca aagatggtta agagagccaa ttccaaatcg gtatcatctt tttctggtcg
     2641 ggcttggaca aaatactggg cacgtttttg aatcacctgt cgctcttctt ccgtcacaga
     2701 atcaaaatct ccgactgcta gagcaagagg taagtcttct tccaagaccc agagcgagcc
     2761 tcgatccacc ccaacaaaag catcaaaatc tgtccgataa tgaccgcggt ttccgcctgc
     2821 aaaaactgca accctagtcc agttgttttc tgagagtttg tactcgctca ttgacttctc
     2881 ccttaaagac ataggaacct gctacaaaaa cagtcgcacc agcttctttg gcttgagcaa
     2941 tagtttggtc atcaatccca ccatccactt cgatttcaaa gttcaaacct ttttcctcac
     3001 gaagagcaac caactcacga accttatcca tggtttctgg cagaaaggct tgcccaccaa
     3061 aacctggatt aaccgtcatg actaaaactt ggtcaactag atgaaggacg tgcttgatgg
     3121 cttcaactgg tgtgccagga ttgataacga ctgaaggctt aactccgagt gaacgaattt
     3181 tttggagggc gccatgaata tgaggtgttg cttctacatg gatactgatg atgtctgcac
     3241 ctgcacgcgc aaaatcttcc agatgatgct cagggtttga caccatcaag tggcaatcga
     3301 aaaccatctt actatgagga cgaaggctct cgaccacacc tgcaccaaaa ctgatttgcg
     3361 gtacaaaatg actgtccatg atatcgatat gggcatattc tgccccagtt gcttctagac
     3421 gtttgatttc acgttcaaag ttggcataat ctgctgccag aattgacgga gcaatcttgt
     3481 attgagacat aggtttctcc ttattttgga atttttttgc tgactttttt ataggtttct
     3541 ctacgatttt caatttcact aaggaattgc aggtaattgt caaaacggaa ggttgcaata
     3601 acaccctctt caacagctgg tttgacggca caagacggct catgggtatg ggtacaagta
     3661 cggaacttac aatctcggct aacagtagca atctctggga aagcctgatt gaggtcttca
     3721 gcccttgata cttcatagtc caaggatgaa aatcctggtg tatctgcgat tttacccccg
     3781 ttgagattgt aaaaactaac agctcgagtg gtatggcgac cgcgacctag actgtctgaa
     3841 atttctcccg tttcaagatt gaggtctggt gcgattttat tgagaagagt tgacttccca
     3901 acacctgtct gccccataaa gaccgtaacc ttgcctgtta acaaagacag gagttcctct
     3961 ttactggtca caaagtcata gccgatgtca ccataggtct gctggtaaaa atccagttct
     4021 cccctatctt ccaacaaatc cattttggaa atatagacaa tgggatggat gcccttgtgc
     4081 tccaaaagaa ccaagaaacg atccagcaaa ttgctgttaa aatcaggttc cttgacggac
     4141 atgattacta cagcttggtc gatattgaca ataggcggac ggaccagact gtttttccgt
     4201 tcgtgaatct tgagaatata gccttctgaa ttttcctcgg cagagaaatc tacccagtcc
     4261 ccaacgtaag gggtatgccc ttttttacgg aaattcccac gcgcgcgtgt ttgatagact
     4321 tggccatcac tctctacata gtagaaccca gccaaggctt taatgatttg tccctgcatc
     4381 ttagagtcct tgccctttaa gtgcgtctgc tagaccggca aattctgcca agctgagagc
     4441 ttccccacgc acacttggcg acaagtctgc ctggtccaaa gccttggtca gcttgtcctt
     4501 gacttcctca gtcttgccaa agtaacctgt caagttattc cacaaggtct tacggcgatg
     4561 ggtaaaacta gccttggaaa ccttaaagaa gaagttctca tcttccactg ctacagctgg
     4621 ctctggacgg cgcaccattt tcaagatggc tgaatccaca tttggcgctg gcacaaagac
     4681 cgtacgaggc acgataaagg caaccttggc tgtcatgtaa tactgcacgg cgatagacaa
     4741 gctaccgtaa gccttggtgt taggctgggc tgaaatgcgg tccgctactt ctttctgcat
     4801 catgaccaca aactcactaa aaggaatgcc actctcaatc aagtgcatga gaataggcgt
     4861 cgtgatgtag taaggcaaat tagccactac cttgattggc aggttaggat ttttaaaatt
     4921 ttggatatgt tgcgccaaat caaccttgag aatatcttcg ttaactacag tcacattatc
     4981 aaaatcacgc agggtatctg ccaaaattgg caccaaacgg tggtcaatct caaaagccat
     5041 gacttgggct gcacgctcag ccaaaaattc tgtcaaggca ccaatacctg gcccgatttc
     5101 gatgacattg acctgatcat caatttcagc cgtatccaca attttttgaa ggatattggt
     5161 atccgtcaag aaattttgcc caaaggactt tttaaaggta aaaccgtgac gctccaacac
     5221 tgccttggtc acgctataat ctgcaattct catctattct cttttctatt atctgttact
     5281 actattgtaa cacattcccc ttgtattttg ggaatgaaaa tcataccaaa aaactatctt
     5341 tcctcatgaa gaaagatagt cttggaaatc tttaaaagtg gccttaacag ttctctcgaa
     5401 acatgcgttc aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca
     5461 catcctcctc cacatcatcc actgtcagtt caaccgtctg aggtaaattt ttcaaacgat
     5521 aatgcttttg cctttgccct tcaatactag caaaatcaag caaatagcca tgcactcgga
     5581 tttgaaccaa aaggagatga ttggtcatat tttccatgat gaggatatct tctaaaccac
     5641 ctctggcact aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt
     5701 ttcctcatat caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg
     5761 atgataattc gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt
     5821 tcaggatcaa gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata
     5881 gtttttgcaa gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct
     5941 aaatccaaat accctagatt aactttttct aaagccccca cttgcctttc caaacgttct
     6001 acttttgaga ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt
     6061 tctaagaggc caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg
     6121 ggaatggttt ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc
     6181 tttcccaaga tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa
     6241 accttgccct tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc
     6301 ttttccaatc cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc
     6361 ttcttctttt ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac
     6421 aactagagcg ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa
     6481 gagaactcct ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc
     6541 aagacgttta atcataagat cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc
     6601 aaataacaag atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc
     6661 cacccgtttg tcatttagta ccttggcaaa aaatagctgg ctttttacca agtaagaaac
     6721 cttgtgatac agaccttgct cttttagagc tgtgatgctg tctccatatc gatctagttt
     6781 caaggcacta ttagccgtag ttccccacaa catccctgca acaggtcttg ttccagtcgc
     6841 ttgcggcgtt agaactacaa taatcggatc ttttaggtac tggcgtgttg tcttgtaccc
     6901 atcattatag aggaaacgtt cctgtcctat ttctgtaaaa gctagcctta cctgtgggag
     6961 gtagtgtttc tgactcgtca cttctacact ttcagatgaa aagttttgca ggtaatctgt
     7021 aaacaatcct tggtagtaga tagactgctc tcgcaagctc tcaggcaaga tcagcccaaa
     7081 ctctccctca gacaagtttt gcatcttgtc cataaactct gaagaaacgg taatcttttc
     7141 ttctatcaga tagcgcggtg agacatagat aacattccct gacggtgtgt agtcactgag
     7201 acgattgcca tctaggtcca cttctgctcc atctgagaaa ttgtcaacat tgctcataat
     7261 ataaaaagag tctgtattgg ctaaccgttc ttcagtaaat gtctgccact cacgattatc
     7321 cttacgcgtt ccttcttcat cggcaaatgc actagaccaa ccaaaggata gacggtaacg
     7381 gtctgaggac tggctccatt tattgctagc tctctccatt tcctgcattt cacggtagtg
     7441 gggtaggaga gctgtcgcac tcgatccgac caccaataca gctaagagtt gccccaccat
     7501 catcaatgtc atcatacgtt tgagagggag tttccctttc aatagatcca ccagactatt
     7561 ttcctgtaaa ccaagtagat agacgacact tagtaaggta gaaatccctg ccaaggtcaa
     7621 tccataaagt agaagagcaa tgatgaccag ttgcaccgtt gccataaaca aggcaccttg
     7681 ataccagaga atccccaatc ccaaaagact ggataccagc actgagcaga taagctgtct
     7741 cacatcttct aacactggtc tgagagcaac tccaaacaag ctctcaccag ctattaagcg
     7801 aatccctgcc tgacgaaggg atttgatccg ataaatcagg gtcagactca taaaggtcag
     7861 cagaaaaata gctaaactca gtagcaccat aggggtggcc gtcaatagta agactatcga
     7921 aaatggatct tctccattcg aaacaaagcc ttgataacca agctctttca aggtggtctg
     7981 taagctcact ccatccaaac ttcctgatac aatcaagtaa gaccctaata aatcactcgt
     8041 ttctgcactc tccttggagg aaatggtcag accttctgga agctttccct caccataagt
     8101 ggcataggta aagcgtgttt ctccagcttc atttggctca acgattcgac gagcaatgag
     8161 actattgtgc tctaccgcca agtgactcaa agcctctgtc acctcttcgc gactagctac
     8221 tggttgattt atcatcattc ctgtcacatc aacagaagga tagttaccaa ataaaatctc
     8281 ttctcgatgg tcaacggaag ttatcaccat ataaagcgat actaatacca ttgaaatcaa
     8341 aataaataaa cgtttcatca tttcctccaa aaagttactt ggtcacttag tgagaaggtg
     8401 accaagtaaa gctaaacaat agggctatac cattctaaac attatagtag aatgcaactt
     8461 tctctcccca agaagtacga atccatgcac gagaagtccc tccagcacca gcatatccct
     8521 tgtcagatga accagttttt ctgctaacaa ctgttgaact atggtatttt gaagggtgat
     8581 agtagtttga gtaagcacca ccgttacctg aaccataagt ccaaacacca ccttctgggt
     8641 attgaacggc tgcagaggca actgctacac ttccacctaa tgttgctgca atgctcgcta
     8701 caagagctaa ttttttaact gtttgtttca tattgatact cctctatttt tgattacaag
     8761 attgttgagt tacttgctcc tctttccatt atcaacgttg atactattat attaccaaat
     8821 gatattctaa aattatttgt ttttctctaa attgtcaaaa tagcaccctg aaatgaactt
     8881 ttatagtcat tatactccat ctttatcaca ctatcaagga catcaatgtc cttaaaatct
     8941 aactatttca tattattttt agcttatatc taaaaaaaca gttctaaaga cgaactttag
     9001 aactgttttg atacgaggac aaggacattt ttgtcactga ttcactatgt ttataaatat
     9061 ttttttaaat cttcttgcca ttgtttttct aacatagtaa ctaaataaga attttctatt
     9121 atatcagcaa atagcttcga tttctgatag aactgttcgg cagaaacata atcattgttt
     9181 attattagag ataatttcca ctccaacatt aatataattg gtttcttctg gaaatcttgt
     9241 gttttttcca ttatatgatt aaggctaaag atataagctc ctagtgaatc ataagacgac
     9301 aaattatcca aacaggctag acccgaaaac aaagtgttac ttaaagcaaa cagatattct
     9361 ggtgcaatta attctacatg atttgtcaaa cgaactaaaa acgaatgaat tctgttaatt
     9421 tcttcaatct gattttgacc ttgttttatc tttgtaagca ctatagcaaa atataagttg
     9481 ataacttcta attcatttat caaaaacaat tccttatcat aaattgtttt aaaataatcg
     9541 tccagtacgg tttccccgta ttctggttgt ccgcttcgaa taacatctat cgttgctcta
     9601 gtagcttcaa accatacttt ctcctcatta ggaagttgct cataaaataa atcctctatc
     9661 tcttccaaac acgcttcttt cttatcatac tcctcttctt tatcatagat tggttcacgt
     9721 aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc cggcataagg
     9781 ctataaactg gaactcctag ccggcgagca atatagtcta acttgggcaa actcggttgc
     9841 gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc atctccacaa
     9901 aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg accaattaac
     9961 atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa aaattgtaac
    10021 ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc aaagtaaccc
    10081 caaacaactc taggcgtttg aggagttgct tgccgttaga atagccgatt cggagagtct
    10141 ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca aggcgaatca
    10201 aatcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc acctgagcta
    10261 gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc cccttggtct
    10321 tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt ggaatggccg
    10381 tcatgatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag acaatgactc
    10441 catgacgttg gtgtagacgc tgaattcgct ctatatcctg atcattgatg gcagaacctc
    10501 gtgtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca tcgcgacctt
    10561 caaccacgat aacttgagaa attttctctt tcattacttg ctgtccaatc caaaaattcg
    10621 ttctgcattt gcagtcgttg ctaccgccag ctcttctgtc gtcataccac gcaagtcagc
    10681 gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac gcttgggtac
    10741 aggtgctaag taaggcgcat ctgtttccac caacatcttg tccaaaggta actctttagc
    10801 tgcttcttgg aggtcagttg ccttcttgaa agtcaccact cctgagaagg aaatggtcat
    10861 accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat gcatgatacc
    10921 accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca gcgcatcacg
    10981 ggtatggaca acaaaaggca aatccaagtc cttagatagc tgaatctgac ggcgaaaaac
    11041 ctgctcctgc acctctttag gcgctgtcat ccaatggtag tctaagccaa tttcacctaa
    11101 agccacaacc ttgggatgtt ttaacttatc caacaagtaa gcctcaactt cctctgtata
    11161 agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat actcatctac
    11221 caactccaag gcacgctcaa tcgtcggttt atcaaaacca acaatattca tctgtgtcac
    11281 acccatctca tcagccaagg caatttcttc tgcctcacga cctgcaaatt cttctacatt
    11341 caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc ttctattata
    11401 ccaaaaaaga ggaggggcac ctaatttttc ggtttcccct cctctcttca atagagagct
    11461 attctgctat cttttctatc cgatattgcc catctcctat tccacagtta gagacagaag
    11521 agattggcta cattgataga atattcctat tcagctaaag tatgtgatta tcttgggttc
    11581 tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt ataatctaac
    11641 tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc tttcttccta
    11701 gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct gcacttgatg
    11761 ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca tcttgcattg
    11821 ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc cactggtctc ttaggaactg
    11881 taaccatggc aatggcttgc actccaatcg tttctgcttc cttcacatct tccatagttt
    11941 tcgcattttc aatctctttg agagctgctt gtttttctgc ttccactctt gctaaaagtt
    12001 ctgctttttc tttatcagaa agcggtgcgc ctttgatttc atcctgcttg tccttggctg
    12061 ctttttcaat ggcattttta gctgattctt tttcagtagc taattgctta gaagcttgtg
    12121 attgagctga gttttgtgaa cctgtgtgag ctgatccacc cgcctggcta ccaccgcctg
    12181 cattcgcatt agcatctgag tttccagtat tgcctccctt atctccacct ggtgtagttt
    12241 ctggcttata ctctggtgta gcttcttgag ttacagattc acctttcgca gattgttgaa
    12301 ctgtatcttt tcctagaatc gtcactactg aaccatctgg gaatgtgatt gttgctgtgc
    12361 catctccagc tacttcaact ttatagtaaa ataaaataat aacaggacaa atcgatcagg
    12421 acagtcaaat cgatttctaa caatgtttta gaaacagagg tgtactattc tagtttcaat
    12481 ctactataac atcgcttccg aatccatttg catctactga acttttttac aaaaataaaa
    12541 atcagtagac tcgagttcct actgattttt gatagaattc gtttggatta tgcagccaaa
    12601 actttgcgtc ctttacgacg acgagctgcc aatacgcgac gaccattttt agttgacata
    12661 cggttacgga atccgtgttt gcgcgcacga cgaagtttac ttggttgata agtacgtttc
    12721 acgatgaata cctcctcata gattttgtat tcgtttagcc ggctataaag tgatcagtta
    12781 ctaaacatac tttactattc tatctgattc tttcactttt gtcaatagct ctaggcaaat
    12841 gtttccagct ttttcgaatg caagccctat ctacgatact gtttcaagaa acgagtcatc
    12901 ttttcttgga tttgggctaa ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct
    12961 ggttcctgcc agttaaagcc tcgaccatga accaagagaa ccttttcctg cttcaagaaa
    13021 tcaaggacaa actgctcatc atcatcgata cggtacatat tgcggtcgat ttttgggaag
    13081 atatagagcc ccgccttggg tttaacggca gacaaacctg gaatatcttg aatggcatta
    13141 tagatgaaat ttctttgctc gtagattcgt ccaccaggaa gaagcaattc atcgactgat
    13201 tggtgacccc ccaaggaagt ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc
    13261 atattggaca gcatattgag cccttcgata tagcccttaa catgagtctt agggccagac
    13321 aagaccatcc aacccacacg gaaacctgct atgcggtggg attttgacag accattcatg
    13381 ctgacacaga agacatctgg tgccaagctc gccacaggcg tatgcacatg tccgtccatt
    13441 accatgcggt catagatttc atccgcaaag ataatcaaat cgttttgacg ggcaatctca
    13501 ataatctcca gcaagagttc cttaggataa agggctccag ttgggttatt tggattgata
    13561 aggacaattg ccttggtatt ggaagtgatt tttgacttga tatcgtcaat atctgggtac
    13621 cattccacag cttcatcaca gatatagtga acggcatttc ctccagctag gctgacagcc
    13681 gccgtccata gaggatagtc tggcattggc actaagacct catccccatt gtccaaaagc
    13741 ccctgcatgg acatgacaat caactcactg acaccatttc caaggtaaat atcatcaata
    13801 tctacgtttg ggaatttctt cagctggcaa tactgcatga tggccttacg ggctgagaaa
    13861 atccctttgg agtcagaata gccttcacta tcacgtgcat tcataatcaa gtcatgaatg
    13921 acctcgtctg gcgctgtaaa gccaaattct gctggatttc ctgtattcag acgtaaaatc
    13981 ttttctccat tcgctcgcat ccgcatggct tcttccaata caggaccacg gatatcataa
    14041 gcaacatgct ctaacttact agacttgtta tattctttca tcttgtttcc tcaattcatc
    14101 aggatagtaa cattatacca ctagaaagag aatgcgacaa gtttactgaa atgtgttact
    14161 agtttcgtat agaaaaaaaa ccttgctaaa ggcgaggtta agaacgtaga gatagcaggt
    14221 attttgcaaa gacacatcac ataccaaaag ataaacctag aaaaagcaag cctagaaagg
    14281 agtcataaag aagattaaac atgaggaaaa gcccccatat catcaagtaa tcccaacgcc
    14341 cacttcgttt tgcaactaga aataagatta gatggtagat tagatggtag agtacatgaa
    14401 agactaaaaa tccaataaaa cctggataaa gaagcggtac cagactctct aattgccaga
    14461 tcatgatcac ttctaccaag actgaaacta ggataattcc ataatacagg aaatttgatt
    14521 tttgaaaaga gtttttcatc attctccctt ccttcacttc tttcctgcta tcctttcttt
    14581 tattttatca tatatttata tagattttaa gccctaatat tcttttgaaa aatacttttt
    14641 ttgctttact tctatagtga aaaggtttac aattatagta agaaaatttc aggaggtttc
    14701 attatggcac aacgttacca aaatatcatg gtcgcaatcg atggttctaa ggaagcggac
    14761 ttggcttttg tcaagggagt tcattctgct ctacgaaacg acgctaaact caccatcgca
    14821 catgttattg acacacgcgc tctccaaagc gtatccacct ttgatgctga agtttacgaa
    14881 gaactccaag tcgacgctga aagtctgatg aaagagtacg aaaaacgtgc taaagatgct
    14941 ggggtagcag atgttcatat cgtcattgaa atgggaaatc caaagaccct gctagcacgt
    15001 actattccag atgccgagga agtggacctc atcctcgttg gcgcaactgg tctcaacgcc
    15061 tttgaacgcc tcttggtcgg ctcttcatct gaatacatac tccgccatgc taaggtcgat
    15121 ttactggttg tgagagaaca agaaaaaacc ttataatcac aaagaaaagg agcccctagc
    15181 tcctttttgt ttacgattta tttctctctt tatggcgttc gtaagccttg agctggcgct
    15241 gcagttcctt tttaatagca ggttctggag catatttttc ttcccaatta tctggtttta
    15301 agattttatg ggtcactgga tcaaaatgag ccttgccatc tggaaaaatt ttccccatat
    15361 tggcctgatg gacaatatca aaaatacgtt ctgggtccac ccccatcaag acaaaactgc
    15421 cgtaggtgaa gtaaagcgtg tcaatcaagg catccacttg ccctatcaaa tcttgctgag
    15481 caggtgtctt cttggctact ttatctgctg ccttatcaag ggcctgatga agttgcgata
    15541 cagcttgacc aaaatcttct tcagaaggac tggctgctcg aacaaactcc accaattctt
    15601 ctattttaaa accagcccta tgggttgcac cctctaaatc ccaagctcga ggttcttctt
    15661 gggttcgttc atccatcatg tggtggaagg tcttgacctt attgaaatga tagtcacggc
    15721 tgacaaagac tttttctgaa gacaaaacac caaaatgttc caaggccttg tggattccat
    15781 cttgttgatt gctagtggta atgtgcttgg cagcttcctt gacactgcta ctaccatttc
    15841 ccatagcgac cgacataccg acgccagcca gcatttcaag gtcattatct gagtcaccaa
    15901 aagccatgac ttggttgagg tcaaagccat attctttccc aactcggcga atgccttcta
    15961 atttagaatt tccctgattg atgacatccg atgcaaaagg attgctacgt gtcaatttca
    16021 agtcttcaaa atcagctgcc gccttctcag attcttctgg tgtcatcaac atcaaaactt
    16081 ggtagatagg ctgattcatc aggtgaagca ggtcctcttc cttttgggga acaaccttgc
    16141 tgaccatgcg attaaaagac tgactcaccg tccgagttaa aacagaggga acgaagcgac
    16201 taattcgttg ggaaaaagaa cccagaccaa aggacatgat tttagaaccc aacatggcat
    16261 ccttggtccc tagagcaatc tccgtgccct cttttttagc atagctaatt agatggcgca
    16321 aatgtaactt ggaaataggg ctcgtgaaca agactctgtc tttactaaag atatactggc
    16381 cattataggt taccgcaaaa tccagatcca aatcgtccat caattcctta acaaaaaaag
    16441 gtcctcgccc tgtcgctacg ccaactagta ccccttgttc tttgacaatc ttaatcgcgt
    16501 ccttagtgga tttcaaaaca ctcttgcgat tgttgaccaa ggttccatcg atatcaaaaa
    16561 aaacagcttt gacttccatc ctattccaat ctcccctttt gtgatacaat gattatacca
    16621 catttcagaa agagttagta aatcatgcct aagaaaatcc ttgttttaca tacgggtgga
    16681 actatttcca tgcaggccga tgcttctggc gctgttgtga cgagttcaga taatcccatg
    16741 aaccatgtgt ccaacccact tgaaggaatc caagtccacg ccttggactt ttttaatctt
    16801 ccaagtcccc atatcaaacc caaacatatg ctggtcctct accagaaaat taaagaggaa
    16861 gcagataact acgatggagt ggtgatcaca cacggaaccg atactttaga ggaaacagcc
    16921 tatttccttg ataccatgga agttccccat atgcctatcg ttctaacagg agccatgcgt
    16981 agctccaatg agctcggtag tgatggtgtt tataattacc taagtgcttt acgagtggcc
    17041 agcgatgaca gggctgctga caaaggagtt ttggtcgtta tgaacgatga aatccacgct
    17101 gccaagtatg tcaccaaaac acatacgact aatgtcagca ccttccagac tccaacacat
    17161 ggtcccctcg gtctcatcat gaaacaggaa atcctctact tcaaaacagc tgaacctcgt
    17221 gttcgctttg accttgatca catacaaggt ttagtcccta tcatctcggc ttatgctggt
    17281 atgacagatg agctgattga tatgctggat ttagaacact tggacggttt gattatccaa
    17341 gccttcggag ctggtaatat tcccaaagaa acggctcaaa aattagaaag ccttctgcaa
    17401 aaaggaattc cagtcgctct ggtatcacga tgctttaacg gtattgccga gcctgtttat
    17461 gcctaccagg gtgggggcgt acagttgcaa aaagcaggcg ttttctttgt taaagaactc
    17521 aacgcccaaa aagctcgctt gaaactcctc atcgccctca atgccggact aacaggacag
    17581 gctttgaaaa actatatgga aggctaatac tcttcgaaaa tctctgcaaa ccacgtcacg
    17641 tcgccttacc gtatgtatgg ttactgactt cgtcagtttc atccacaacc tcaaaaacat
    17701 gttttgagct gacttcgtca gtttcatcca caacctcaaa aacatgtttt gagctgactt
    17761 cgtcagtttc atctgcaacc tcaaagcagt gctttgagct gacttcgtca gttctatcta
    17821 caacctcaaa aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt
    17881 gtgttgcgca gcctttaacc agccgcctag tccgctctat ggtattcatt aagtcaacat
    17941 ctcttgttta agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac
    18001 gttttcgtgt tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca
    18061 actcttcctt atgcataatc ttggtcaaca tacgcatact aatggcacca aggtcataaa
    18121 gaggttgggc aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac
    18181 tagtaataat ttcaaaatct tctggcacag aaacaccttt atcagccaaa ccgttcaaga
    18241 ctcctgctgc caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac
    18301 gctctgctaa ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac
    18361 tataagtgat tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat
    18421 tgatgtcatc cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt
    18481 aactcactgc atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct
    18541 caacatcgac agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa
    18601 ttttatctgt caagtgataa cccatataga taatgccatc tacctgcttt gaaaagaggg
    18661 tattgacaac agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt
    18721 acttgtacat ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg
    18781 taatatttgg aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa
    18841 ctgcatttgg acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct
    18901 cttttacatt tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt
    18961 cacgagcgac atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt
    19021 ctatctcaca cattctttta caagtagagg tgctgattga agctctatat ctacttacaa
    19081 aagtgaagat gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg
    19141 taaacacttt caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt
    19201 tagctccttg ctaccacctt agactaaaca aaaaggagga aactaagccc tcctaaagtt
    19261 atagtaaaat gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca
    19321 atgttttaga agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt
    19381 cactaccgtc aattttagca catagtcttc atgaaaatat tatatcatca taaccaacca
    19441 gattcttttg cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata
    19501 ttggtgacat agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg
    19561 ttggataagc cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg
    19621 ggacgggtca tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg
    19681 gtgtgcaagg tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatccact
    19741 ccagccttga ccgcacgttc aaaataccca gcacgcttga aggtcgtcac cacaaccacc
    19801 tttgtttcaa gcttttctga tcgtatccac tccaagactt caagacctgt cttaacaggc
    19861 atttctacgt caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct
    19921 tgcccatttt tggtttgaag gacagactcc acatctggtt gaagcgtgag caattgacac
    19981 atggcatctc gcaacatact ttgatcttct gcgactaata ctttcatctt agtttctctc
    20041 cttataaggt agtcgaactt gcacttccgt tggatgtttc tgactgatta cacttacttc
    20101 tcctgaaaat ggaaaaacac gatctcggac tgtatggagc tcatctcctt ttagaaaagc
    20161 aaagccgcag ccatcatcac ttactgttaa aatgagttcc ttctctgtcc gttctaattt
    20221 taagtaagct ttagacgctt tggcatgttt gatgatattg gtcaccaact caagcaaaat
    20281 catagaagcc attgaatcca attcttgagt aaggctagca gtatctagtt ggttatctgt
    20341 ttccacctca attccagcaa tttctaacat ctttttcaca gtctctagtt cggatgtcaa
    20401 agttctagac ttaagatttt ccacaatggt tcgaacttca cacattgatt ctttgctaat
    20461 ttgctgtatt tctcttaatt ccttttccac ttgtggataa gcctgcattt gaaatagctg
    20521 caaggctaga tctgtcttga cactaagcat agcaaaggta tgtcccagac tatcatgcaa
    20581 atcctgaccg atacgattgc gctcattttc tgctagcaat agatttatct gggtattttg
    20641 cttgacctga gcttctttca aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat
    20701 caaatcgaca aaagtaagaa ttacaagcat atagactaga aactcaactt cgattctctg
    20761 aaaaatcaaa agtcgcccca caacaaggac ttgagcaagg agaaatgtcc atacatgtaa
    20821 agactttaaa ctacgtacgc caaaatgata aattaagaga ttggaaagga aaaagaaaaa
    20881 ccagatataa ttcccagcaa caaaggcggt attcccagct acatagacca gcatgagccc
    20941 ccagaaaagc caagataggc gctggttctt agttattaaa acacccaaat acgtcactac
    21001 aaatagaata tcaaccaata aatgccaagc aggaagctcc ccaatcacta caggtaggat
    21061 gggaaaaagc ataaaaatca aactggtcca aaacatatag tgtatgcttt tcagtctttc
    21121 aagcattaag cattctcctt atgaccttga aggtaaatag tcaaaccaaa taaaactgct
    21181 gaaaaaacaa gtaaataaac tgtggctgat agattgatgt caccctcgtt taagaaggtc
    21241 ttgagcaact ccatcaattg ataggtcggg agacacttac caactgcttg catccagtct
    21301 ggaaataaag aaatgggcat ccagagtccg cctaaaacag ccaatcctag ataaagaaga
    21361 ttgcccacaa cagacatcag ctgactagtt ggtaagagag tcaaggtcaa gccaagtgct
    21421 acaaaagcaa tactccccac aatcagcaaa atcgcagctc caacccattt tactagaggc
    21481 atgtctacac ctcttacaaa atgtccaact gtaaaaacaa ccagaattga gaccaaataa
    21541 tcaaccagca tacttgttat ctttgataga taatattcta ccatatttac agggctatga
    21601 cgcaatgttt tctgccagtt gttcatctta tcggtatgta aaacagctgg aaatgagagg
    21661 atagttgtcg acatcatgga aaaggcagtc atggagatga ggtaatcacg cataaaattc
    21721 gcgagttcac ctggtgtgtc ctgatagata ccagaaaaaa ataaatagaa agccgtcggc
    21781 atccctaccg acaatagata atagattaat tgtcgtttgg tcaataaaaa ttctatctta
    21841 ctaagtgcta tccatcgttt catcttagtt atctcccttc tgcgtctctt caaagattgt
    21901 attcaacaaa ctacgattat taacttcgat ttcttgcatc ctacatcctg cttgggctaa
    21961 tagttcccag aaagcatctg cttctcgagt gactacttgt aaagaatctt gctttagggt
    22021 ccagttttca accaaatttg actgctctac gacttccttg taagctatag gaaggataaa
    22081 gtgcttttct atttcctcgc tacgcatagc tagaggcgtc gtatctcgaa tcaactctcc
    22141 cttatttaag agcaaaatgc ggtctgcagt gtgttccact tcctcaatat aatgggacga
    22201 atagagaatg gtgactcctt gcgcttttaa ctcctggaca atttcccaaa aacgttgacg
    22261 agttgaggta tccatggacg cagtaggctc atctaaaaaa acaatctttg gtcgcccaat
    22321 taaggtcaag acgaaagaaa agagacgctt ttgaccgcct gataattttt ctgccaactg
    22381 ttctttttgt tgcttgacaa actgcaatag ttgatcaatt tcctgattgc tcaaaggatt
    22441 tggatagata cgttgaaaga aagcaatcaa ctctttaact tttaatttct gaacgattac
    22501 attttcttga gggaggtaag ccctagtata gtctaactta gaactcgtca ctggtaaacc
    22561 ttgaatagat acttgaccgc ttgtgaccag tttatctcca agcaaacaat ctaagagtgt
    22621 tgtctttccg gcaccatttg gaccaattaa ggcaacacat tcaccatcgt tgatttcaaa
    22681 ggagatattc cgcaaaattt ccttgtcttt tattttctta ctcaatttct caactttaac
    22741 caccgtcatg agactctcct ttcaaccact ccattcccat aaggaaaacg acgaaaatca
    22801 taaatccaaa ccccaaagca ccacgaatga attggcgaag caaggcttga tcaaaccaat
    22861 cagtaaacat ttccactaac cataccaaga gtgacaggcc gataaagaaa tagatgatcc
    22921 ctctcttcat tcctcaaact cctttttcac atctctgact aatttcaaac cttctctaac
    22981 aagccaagac atgattccaa agccagcaaa gaccttccaa ggaaaatggt agaaatcctc
    23041 atccaatccc gaaaacatga gataggtcat aactcctgct actactaaac tcattgcaat
    23101 aatcatttta tttctcatct cttcttcccc catttcatac tacaattata gtcttttaaa
    23161 atcagaggag gcagaagctt ctgtcactag aaaatatgac aaatgtcata aaaattctgt
    23221 tcaaaacaag caagatacac tatacaataa aacacaatca gaaaaatcta aggcaacttc
    23281 ctcaaaagag atatcaaacc caattcacac cataatgtaa actaatactt atttaaaatc
    23341 aaaaagagta gaaattttta tcagacaaac acatatatag
//
LOCUS       DAVKZI010000034        21641 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKZI010000034 DAVKZI010000000
VERSION     DAVKZI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.035"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(174..392)
                     /locus_tag="VXB18_001558"
     CDS             complement(174..392)
                     /locus_tag="VXB18_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382741.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(638..916)
                     /locus_tag="VXB18_001559"
     CDS             complement(638..916)
                     /locus_tag="VXB18_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382742.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1130..2752)
                     /gene="rlmD"
                     /locus_tag="VXB18_001560"
     CDS             complement(1130..2752)
                     /gene="rlmD"
                     /locus_tag="VXB18_001560"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0382743.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDHVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREH
                     YNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2826..3800)
                     /locus_tag="VXB18_001561"
     CDS             complement(2826..3800)
                     /locus_tag="VXB18_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0382744.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3874..4488)
                     /gene="pmp23"
                     /locus_tag="VXB18_001562"
     CDS             complement(3874..4488)
                     /gene="pmp23"
                     /locus_tag="VXB18_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0382745.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4488..5462)
                     /locus_tag="VXB18_001563"
     CDS             complement(4488..5462)
                     /locus_tag="VXB18_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0382746.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5470..6726)
                     /locus_tag="VXB18_001564"
     CDS             complement(5470..6726)
                     /locus_tag="VXB18_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0382747.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6788..7219)
                     /locus_tag="VXB18_001565"
     CDS             complement(6788..7219)
                     /locus_tag="VXB18_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382748.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7221..7823)
                     /locus_tag="VXB18_001566"
     CDS             complement(7221..7823)
                     /locus_tag="VXB18_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0382749.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7807..8646)
                     /gene="prmC"
                     /locus_tag="VXB18_001567"
     CDS             complement(7807..8646)
                     /gene="prmC"
                     /locus_tag="VXB18_001567"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0382750.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8646..9725)
                     /gene="prfA"
                     /locus_tag="VXB18_001568"
     CDS             complement(8646..9725)
                     /gene="prfA"
                     /locus_tag="VXB18_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0382751.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9735..10214)
                     /locus_tag="VXB18_001569"
     CDS             complement(9735..10214)
                     /locus_tag="VXB18_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382752.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10204..10803)
                     /locus_tag="VXB18_001570"
     CDS             complement(10204..10803)
                     /locus_tag="VXB18_001570"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0382753.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10926..11108
                     /locus_tag="VXB18_001571"
     CDS             10926..11108
                     /locus_tag="VXB18_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0382754.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11244..12617
                     /gene="mnmE"
                     /locus_tag="VXB18_001572"
     CDS             11244..12617
                     /gene="mnmE"
                     /locus_tag="VXB18_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0382755.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDIEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12664..13599)
                     /gene="dapA"
                     /locus_tag="VXB18_001573"
     CDS             complement(12664..13599)
                     /gene="dapA"
                     /locus_tag="VXB18_001573"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0382756.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13655..14731)
                     /locus_tag="VXB18_001574"
     CDS             complement(13655..14731)
                     /locus_tag="VXB18_001574"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0382757.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15317..15389)
                     /locus_tag="VXB18_001575"
     tRNA            complement(15317..15389)
                     /locus_tag="VXB18_001575"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15354..15356),aa:Thr,seq:ggt)
     gene            complement(15489..15998)
                     /locus_tag="VXB18_001576"
     CDS             complement(15489..15998)
                     /locus_tag="VXB18_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0382758.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15996..16092)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16121..16552
                     /locus_tag="VXB18_001577"
     CDS             16121..16552
                     /locus_tag="VXB18_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0382759.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16634..17011
                     /gene="mscL"
                     /locus_tag="VXB18_001578"
     CDS             16634..17011
                     /gene="mscL"
                     /locus_tag="VXB18_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0382760.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(17053..18147)
                     /gene="hemH"
                     /locus_tag="VXB18_001579"
     CDS             complement(17053..18147)
                     /gene="hemH"
                     /locus_tag="VXB18_001579"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0382761.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRINENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            18302..19525
                     /gene="pepT"
                     /locus_tag="VXB18_001580"
     CDS             18302..19525
                     /gene="pepT"
                     /locus_tag="VXB18_001580"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0382762.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(19561..20190)
                     /locus_tag="VXB18_001581"
     CDS             complement(19561..20190)
                     /locus_tag="VXB18_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382763.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            20155..20376
                     /locus_tag="VXB18_001582"
     CDS             20155..20376
                     /locus_tag="VXB18_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382764.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(20453..20994)
                     /locus_tag="VXB18_001583"
                     /pseudo
     CDS             complement(20453..20994)
                     /locus_tag="VXB18_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(21098..21641)
                     /locus_tag="VXB18_001584"
                     /pseudo
     CDS             complement(21098..21641)
                     /locus_tag="VXB18_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6257 a         4511 c         4008 g         6865 t
ORIGIN      
        1 catattttta ggtaaatacc aaccatctag cttatttgaa tatcccttga agcctaattg
       61 attaaaagta gttatttgac cagtaccttg attgatgttt tcttcaactt cattaaagcc
      121 tatacttctc ttgcataatc cctaacttga tcttctgtcc ttaaagtcat tttctattcc
      181 tcgtcactaa aattatcttc aaaactaata atatcattag gagtgcaaga taaagcctta
      241 catattcttt ctaaattctt aaatgtaatt ggtttatcct ttcccatttg tgccataaca
      301 tttgttgtaa gtcctgccat agctattaca tctgttttct ttagtccttt ttttgctaac
      361 tgtatccata atggtttata gttaagtgcc ataatatccc tctttttttc ttcattagat
      421 ttatttaatt atagcataaa tattgatttc attcaatctt acattgattt agtgatttgt
      481 tttagagaat ttgttgtgtt attccgtcct tattttgcca taaattgttt taagtgggac
      541 ctcttatcct taccattttt acctcctaat tttgagtata aaaaagacga tagagttttt
      601 aatttctatc gtctgagatt tacatattaa attttcatca caaaataaga ctctttaaag
      661 aatctttaaa ttcattggta tgctgcttac aatatccatt attaaaatgg atattgtaag
      721 cagcacacca actatttatt ttttgagttt taaactttgg tagaagtctt gaactcctta
      781 tatttacata actatttgcc tctataacta ttatgacacg aaaccaacaa gcaagttcaa
      841 gcacctccat atctttattc aaatgaggac taagatattc acaaacttta tcataaacct
      901 ctttatcttt tttcataaaa ggggcataca acttagcaaa tttatcctaa aattttttgt
      961 tgcctttatc aatcatttca acgctccttt aaatataaaa atgatcctat caatctttat
     1021 tttgagccta ttttctaatt gataccttgc aagaaaggaa taatagctgt tcctatacca
     1081 agtaggaatg taataaatgc agaaagtcat atactgtcat tcttttctat taaatcattt
     1141 tgaagtgtct caaagcatcc atgatggctt cttctttttc aggtgtacac tgtggaataa
     1201 tttgtttatc ctttttagac ttgttgtaat gttctcgtaa ttctattcca catttctttt
     1261 ttatctgtgc aatatataat gtcgaaactt ttaattcaaa tttattccaa acatattctt
     1321 tgatttgagc atatgttgct ttgctctccg cacttgtcaa atccagctca atttcaacac
     1381 ttatgtgctt atcgacatcg agtttagaca aaagtgctac cgtctcgacg tgatgcgttt
     1441 gaggaaatag atccaccggc tggactttct tcaattcata tcccaattct tggtagagtt
     1501 tgatatcacg cgccatggtt gcgacattgc aggagatata ggcgatgcga tcggctcctg
     1561 tttgggcgct tgctttgata aagctttctg tcaagccctt gcgtggagga tcaaccaaga
     1621 taacggttgg ttgaatccca tctttaagcc aattcttcat agcattttca gctgtgtcac
     1681 agacatagtg ggcgtttgaa atattgttca gctgagcatt ttttttacta ttctcaaccg
     1741 cttctggaat cagttcaaca ccgtagactt ctttgacatg cttggcgact gataaaccaa
     1801 tggttccaat accagaatag gcatcaataa tcacgtgatc tttttttaac tctgcaaagt
     1861 caatggctgt ttgatagagt ttctccgcca tttcagtatt gacttggtaa aaggctgggc
     1921 cagcgatttg gaagtcattt cccaacatct ggtccgtaat atagtcttga ccataaagag
     1981 tgcgccactc cttaccaaaa atcgcattgg tattctggtc gttgatattt tgcatgacag
     2041 acacaatctc tgggaactgc ttgataactt gttcaatcaa ttggtcaaca cgaaaaactt
     2101 ttggacgagt tgtcaccaaa acgaccatga tttgtcctga atagtgacca cgacgcacca
     2161 caagattccg aatcaatcca gactgttcct tttcgtcata aggttttaaa tcaaaacgac
     2221 ggagcaggtc tcgaagagct actacgactt ggtcaatgac aggatcctgg ataaagaaat
     2281 cttcaagggg catgaggttg tgcgaattct tacggaaaaa tcctgtttcc aagacaccat
     2341 tcactcgacg aacgggcacc tgcgccttat tgcgatactt gactggatgt tccataccaa
     2401 gcgtttcagc aacttctaca tctgcaattc cagcaatctt gtagagactg tccttgactt
     2461 gcttggtttt aaacttgagc tgttctggat aagaaaggtg tcctaaatcc gcgattcctg
     2521 aacgcaggta agccaaatct agatcttgat tacggtgtgg tgactggaca aggtattttt
     2581 caacttttcc aaagccaatc tttttattga ccttgaggac acgcatgaga attttttcac
     2641 tcggtaaagc attctctaca aaaaagacca aaccatctac cttggcaact cctgcccctt
     2701 catgggtcaa atcaacaatt tcaacttcta caatatcatt tttctttaac attcttttct
     2761 ctttctattg gccgacaaaa aagacggcaa cgttacggtt accatccatt ataccatgaa
     2821 atttcttaag aaccaaaact cttgaagaag ttgacaaggg cttgccagag ggagcttaag
     2881 aagttaccac cgtcctctag cgccttatcc gcatcaaagt taaggttgat atttttaaaa
     2941 ctgtcgccag cttgtgatac gatgctttgt ttaaggtcat ttagggtttt agtgaaatct
     3001 gcattgctga ggatatcact ctttgagaga ttcaaggcaa aattgatgat gatattgatc
     3061 tggtttcctg ttatgacctg atcaagtttg taatttttta aggtatcttc aacaatcttg
     3121 cggatatctt cttctgtcag atttcccttg ctttctttag ctttggcgag tcctgacttg
     3181 atatcagcta gggcaacgtt taatttatta gcatcatagc ctgatttgtc cttgttttca
     3241 gcattgatat ctgacaaagc ctttagctct tcttgagcca aatctttatt ggcttgcggc
     3301 accttggctc cattagcttc tagcgaatag tagatcccag ccaaagcact ctcacctgta
     3361 actggaatgg gtgctgctac agtgattttg gcgtgttcca cacccaaagt tacggctgca
     3421 tttcggtaca tatcctgagt taccttagtg atgttttcag gtgtttcaat cttgacctca
     3481 agtggcgatt tgtcacctag cttttgaatc ttggctgatg aatacaactg taagctagag
     3541 tcattggcca cattcatgat tttagaataa acatcaggtg tcatggtctt gagttctttg
     3601 gtatctgttg aggcattgta gcccagtttt ttaagagttt gatttttttg gtcttcagat
     3661 agggaggaac ctaggacata ttcaggttgg acataggttt catcgataac tttttgaaca
     3721 tctgttgctg catggacgct attcatagct gttactgccc acaagaccgc agcactagtc
     3781 agaaagagtt tctttctcat agggaatttc ctcctttact tctttatagt aatatatcta
     3841 tcttaaagaa aacttataac aaaaacacct ggtctagcca gatgttgaaa agagagtgaa
     3901 acatttgatg atgtaaaggt taagtcgtac ctgtctagaa taataatagt ttcctccatt
     3961 tacatagagt tcagcaccgt gaaaaatgga aatggggtga atataactat aagtctttcc
     4021 agtcgtatta ccaagcaagg gggcaacagt ctcacgagag tactgtttgg ctagagccaa
     4081 ggtattttcc ttgccatttt gggcgataaa atcgatatag gcaggtccaa aattataggc
     4141 ttgaacagct gtccagatat ctacaccctt cttctgcgcc agatagagat tgcctgtcag
     4201 agtttgaatg ccttgccgaa tgctagaggc attatcattg atggtgttgg tggaaccact
     4261 tgcagactca ctagactgca taacatctcc ttcttttcct tttgtttcag tataaatcat
     4321 agcaagcaca agctcttcgt ttgctggggt gtctttttca ctcaagattt ctcgcaccat
     4381 gggttgatag gtcatgactt gtttgacatc ttgatgaacg cggtaagctt tatagccagc
     4441 aaaaaggaag actgctagta caagcactct tcgaattcgt ttaaacatta tttactttgg
     4501 atatcctcga tatttttgat taagatagag taggttccat tttcgttttg gataaactca
     4561 acagactcgg cgtcttgata gacgttattg ggaacgatga gctcaattcc atttgataag
     4621 gagagttttt ggttttcaaa tttctttaat tggcgactgg catcaatttc atcaaattga
     4681 acaggttctg gtacggcttc tttgacttgg tcaataaagc tcaaacgagc cgtcagattg
     4741 ttgtcaaaaa ggtcattagc caatttctca ggtgacaatt cattgctttc ttctaggttg
     4801 ttgaaaatcg ctgatttgac cttggattga aattgaaaat catctgtgtt aaaagattca
     4861 gcaattctct gggctgtttt ttccagttcc ttgatagatt ttttaggaga aatcttagga
     4921 gcgacagcaa gaagattatc tgaaaaatag ttcaaaaaag tcccgttgta cttgattcgt
     4981 ttttcaatca ggtgatactt gctactctga agattgacca ccaaggcctc atcagctcct
     5041 gttccaaatc caggcaggtt attctgagtt agcttgattg gattatcaac ttctcctccg
     5101 aggtgggtca aggtctcccg cagggcaatt cgcaagaaag cgaaatgttc tacaccttct
     5161 ttagaaaatt gaacaaaaat caagtcattg gtcttgagat tttcagaaat gctaaactcc
     5221 tctttccaga gattagccag cgttactgat gtctccaaca aatcgtctgt aatatgattg
     5281 aagaagggat tttcttcttc gaaaatccca gtcttggctt catctgaata cacatgttca
     5341 atttttttac gtaggtattc ttcgattttt ggagtaatat tgagaaactt atctgctaag
     5401 aacagctcgg tatcatccgg actgaactgg tgaataatgg ctttcttaat ataaatgtcc
     5461 ataaaagttt tattcctcgt ataatgggaa ggcatctgtc aattctttga ctgcacttct
     5521 cacttcttct aatacagcct cattttctga attcttaagg gttttaatga tgagttcagc
     5581 cactttgcga ctttcttctt caccaaatcc acgtgcagta atagctgctg ctccgatacg
     5641 aatcccactt gtcttgaatg gtgacaagct ttcgtaaggg attgagtttt tatttaaggt
     5701 aatattgact tcatccaaca agttttgagc aactttgccg ttttctacaa ctttagtcac
     5761 atcaacaagg aagagatggt tttcagttcc acctgaaata atacggaaat cagggtcttg
     5821 caagaagaca tctgccatag ccttgctgtt cttaattaca ttggcagcat attccttgaa
     5881 ggctggatcc aaaacttctt tgaaggaaac tgccttagcc gccacaacat gctctaaagg
     5941 accgccctga atacctggga aaatagctga attgattttt ttagcaagtt cttcgtcatt
     6001 ggtcaaaatc aaaccaccac gaggtccacg aagggttttg tgggtcgttg ttgttgtgat
     6061 atgagcgtat ggaactgggc ttggatgaag gccagccgca accaaaccag cgatatgggc
     6121 catgtccacc atgagcttcg caccgacagc atctgcgatt tcacggaatt ttgaaaaatc
     6181 gataatttga gaataggctg aagcaccagc tacaatcagt tttggtttta cttcttgggc
     6241 ttgtttcaag atagcatcaa agtctaagag ttccgtttca ggatcaacac tataagaaac
     6301 aaagttgtag gtttgaccag agaagctaac aggagcccca tgagtcaaat gaccacctga
     6361 tgccaaatcc attcccataa ccgtatcacc tggctcaatc aaggacatgt aagccgcaca
     6421 gttggcctga cttcctgaat gtggttggac attggcaaat ttagcaccga aaatttcttt
     6481 tgcgcgttca atagcaagag tctctacaac gtctactaca tcagttccac cataataacg
     6541 gcgtcctggg taaccctcgg catatttatt tgtcaagata gacccttgag ctgccataac
     6601 agccttggaa actacgtttt ccgaagcaat taactcgata ttattttgtt ggcgttcttc
     6661 ttctttggca atagcattcc agagatcagc atcatatgct ttaaaatcat ctttgtcaaa
     6721 aatcataggt cttctccttt attgtgtgac tagtccatta gtttgatttt acaataagaa
     6781 aatcaaacta aaagatgcga ataaaccgtt tctgcatttt atcacaagta tagccaactt
     6841 tttcataaaa tgcatgagca cccagacgat gattggcaga atttaagcgg ataaacccat
     6901 aaccacatct tttggcttct tgttccaacc cttgtagtaa acttttaccg ataccttgac
     6961 cttgcgcttg aggtgaaact gctaaagcta agatattaaa tcctgctttg gaatagagtg
     7021 attcgtaaac ttcagcgtgg acatatccaa gtaagacatg attagctgca tcctcatagc
     7081 caagtaggaa atgatgggaa tcctgagaca gtctagctag ttggctagcc gtttcctctg
     7141 gactaaaagt ataacccaaa gcctcttggt tgatgtcaca tatcgctttc acatctgttt
     7201 cttgcaaatc tcttagcatt tcaagcctcc tcaaaagaaa tctctggcaa ccgagcaaga
     7261 atatcttctc gtttaattgc gccttggcgt aagattttca ccttgtctcc agacaaatcc
     7321 acaatagttg aatcctgtcc agttagaaaa gcatcgtctt ccagacccag aacctcttgg
     7381 tcaaaatcct tcagaatttg ttcaaaggtt acaccacttg cctgacctga gatattggca
     7441 gacggcccaa tcaagggacc tgtctctcga attaaatcca gtgtgatagg gtgactgggc
     7501 atccgaaatc caatagttgc aaggtcagaa tttacccaat agggaactcg gtcattggct
     7561 tcgagaataa tggtcaaggg acctggcaaa aaggtctcta caagtttttg tagataagct
     7621 ggctgattct ttgaaaagtg caagatgtcc tcgaaagagg cgatattgag attgagtgcc
     7681 ttatctctag gacgacgttt gagttggtaa acatggtcaa ctgctttttc atctaaggcc
     7741 ttggaaaaaa gaccataaac agtctctgta ggtagaacga cagctccacc attttccaac
     7801 tcttgtctaa tcctgtccat catcaaccac aaccatccta ttttgaccaa attggtcctt
     7861 gagtgttcga actctttttt caggaagatg tttcctaaaa agttcgggaa cactttgacc
     7921 ttgcttgtat ccaatttcaa ggtaaatctt accaccatct ttgagatagt cttttgcatc
     7981 ttccgcaatt ctacagtaaa tagctaggcc atcctcgtct gcaaagagag ctagatgagg
     8041 ctccgaatgc aaaacattca agcctacctc tgactcatct tcacgagaga tatagggtgg
     8101 attggataca attatatcat atttttcaga aatttctgca aaacaatcag attttttaaa
     8161 aaatatatta agattttgat tgctagcatt ctctgatgca agctctaagg cctcttgaga
     8221 aacatctgct gctgtcactg accaatctgg tctatttttt gctagagcga gagcaatagc
     8281 tccactacct gttccaatat ccagaactga gagattcgtc tcaagatttt cagttagaat
     8341 aagctccact aactcctctg tttctggacg aggaatcaaa acccgttcat ccacctttaa
     8401 atgcattcca taaaaatctg cctgtccaat gatgtactga gctggcttgt gagctgctag
     8461 ttgctggtaa atatcttcta caaattgttt ttcttcctct gttgtcacct cctgctggag
     8521 ggcaaaaata aagtctgtaa aagatagatt tttcagacta cgatagacaa aagagaggct
     8581 ttccgcttcc tctccttgtc ttatcaactc ttcttcaaaa tttgaaaata attgagctaa
     8641 tttcattatt tgtttaattc ttctagtttt tgtgtttggt cataaagcac caaggcatcc
     8701 acaacttcgt ccaatttacc agacaaaatc gtatctagtt tttggagggt caagccgata
     8761 cggtggtctg tgacacggtt ttgtgggaag ttataagttc ggatccgttc tgaacggtca
     8821 ccagtaccga ttgtcgactt acgctcagcg tcctgctcat cttgagcaat ctgagcaaag
     8881 tggtcagcaa cacgggcacg gatgattttc atggccttct cacggttctt ctgctgggta
     8941 cgttcttcct gcatctcaac cttgatattg gttggcaagt gaacgatacg aacggcagtc
     9001 gcaaccttat tgacgttctg tccaccagca ccagaggcgt gatagatgtc gacacgaagg
     9061 tcttttggat caatgtcgta ttcaacctct tcaacttctg gcataacaag aactgtcgct
     9121 gtcgaagtat gaacacggcc ttggctttct gtcacaggaa cacgttgcac acggtgggca
     9181 cctgattcat acttaagctt agagtataca gactgacctg aaaccatagc aaccacttct
     9241 ttaaaaccac cgacaccatt catagaggct tccatgactt caaagcgcca accttgggct
     9301 tccgcatact tttggtacat agttagcaaa tctccagcga aaagtgccgc ttcgtctcca
     9361 ccagctgctc cacggatttc aaggatgata ttcttgtcat cgtttggatc ctttggaagg
     9421 agcaaaattt tcagtttttc ttcatattct tctttttcag ccttggcatc tttgagttct
     9481 tgcttggcca tttcttccaa gtccgcatct ccgcctgatt ccttaatcat ctcttcggca
     9541 tcgacgatat tttgaaggac ttgtttatac tcacggtagg ctattacggt gtcacgattg
     9601 gaagcttctt cttttgaaag ctccataaaa cgcttggtgt ctgaaacgac atcagggtca
     9661 ctcagcaatt ctcctagttc ttcataacgg tcttctacag cttgtagttg atcatagatg
     9721 ttcatttttt ctccttattt ctcaattgtt aaatcataga ttgctactac ttcattctcg
     9781 gatatttccc cagtttcttt aaatccataa ctgagataac aaaatcttgc ctgttcattt
     9841 tctggttcat aagacaacca aagtttattg cttaaacctg ctggcgctgt tcgaacatag
     9901 tctagtactt tatccataat tggtttaaaa tatccttgat tttgaaaatt cttatcaatc
     9961 ataaaacgaa atagtaaata atttccacta ctaattccga tctttttatc ataagctatc
    10021 atcacaaaac ctataattac atcattatca taaactgcca atggagctac aaaatctcca
    10081 tttttagtgt agacgtatgc ttcagctaaa ctaattgcgt tggttgcaat gaattgtttt
    10141 tgatattcct tgacatccaa atttaaaaca tcaaaataat tttccattgt aacatctctt
    10201 agttcaattg tcatagtttt gctccttgtt agaggttatc attggcgcaa aataatgttt
    10261 acggcaaacc gagatatagg tttcattacc accaatctgg atctgttctc catcgtaaac
    10321 gggcagtcca tcctgtgttc gcaacaccat ggtcgccttt ttcttgcaat actgacagat
    10381 ggtcttgatt tcgtcaatct tgtctgctaa aagcaagaga tatttggaac cttcgaacaa
    10441 ttcattgcga aagtcatttt tcaagccaaa agccatgacg ggtatgtcta actcgtccac
    10501 aacacgagct aggtcataaa catggtggcg tttgagaaac tgggcttcat cgaccaaaac
    10561 acagtaaggt ttttctggta ggtctcggat atagccaaag atatccgttg tttcctcaat
    10621 cgcaagggca gggcgtttca tgccaattcg actcgacaca tagccaacac cgtcacgcgt
    10681 atccagagcc gaggtcataa tcacaacacc ttttccttgc tcctcgtagt tataggccac
    10741 tttgagaatc tcaatcgttt taccagagtt catggtccca taacgatagt acaactgtgc
    10801 catgtttctt gcttcacgtc catttctaaa tttttgctac attctagtat atcataattt
    10861 tcttaagctt taaacggcaa aatgtggtaa aatggaagaa atcaaaacta gtggaggaag
    10921 ctattatgcc atttgtacgc atcgatttat ttgaaggacg cacgctcgag caaaagaaag
    10981 ctcttgctaa ggaagtaacg gaagcagttg tccgcaacac tggagcacct caatctgctg
    11041 tccatgtcat catcaacgac atgccagaag gaacttactt cccacaaggg gaaatgcgta
    11101 ctaaataagc tagcttaagc agaattgctt aggctttttc aatctccaag tagcacccat
    11161 tgaagaaata gtctaaattt gttacaattt gaaaagagac ttggaaaatt ccaagaaaag
    11221 agcaattaat taaaggaaac attatgatta cacgtgaatt tgataccatc gctgctatct
    11281 ctactccact aggtgaagga gctattggta ttgtccgcct gagcggaaca gacagttttg
    11341 ctattgcgca aaagattttt aaaggaaaag acttgagtca ggttgctagc cacactctca
    11401 actacggtca cattattgat cctctgactg gtaaagtcat ggacgaggtt atggttgggg
    11461 ctatgaagtc tccaaagacc ttcactcgtg aggatattat cgagattaac acccacggtg
    11521 gtattgcggt gaccaatgag attctccagc tagctatccg tgaaggagct cggttggcag
    11581 aacctggtga atttaccaaa cgtgcctttt taaacggtcg cgtagatttg acacaggccg
    11641 aggcggtgat ggatatcatc cgagccaaga cagacaaggc catgaacatc gcggtcaaac
    11701 aacttgatgg ttccctttct gatcttatca ataatatccg tcaagaaatc cttaacacac
    11761 ttgcccaagt tgaggtcaat atcgactatc ctgagtatga cgatattgag gaagccacta
    11821 ctgctgttgt ccgagagaag acaatggagt ttgagcaatt actaaccaaa ctccttagga
    11881 cagcacgtcg tggtaaaatc cttcgtgaag gaatttcaac ggctatcatt ggacgtccca
    11941 acgttgggaa atcaagcctt ctcaacaacc tcttgcgtga ggacaaggct atcgtaacag
    12001 atatcgctgg gacaacacga gatgtcatcg aagagtacgt caacatcaat ggtgtacctc
    12061 tcaaattgat tgatacagcc ggtattcgtg aaacagatga catagtggaa caaatcggtg
    12121 ttgagcgttc gaaaaaagcc ctcaaggaag ccgacttggt tctactagtg ctaaatgcca
    12181 gtgaaccact gactgcgcaa gacagacaac ttcttgaaat tagccaagat accaatcgca
    12241 ttattctact taataaaacc gacctgccag aaacgattga aacttcgaaa ctacctgaag
    12301 acgttatccg tatttcagtc cttaaaaacc aaaacatcga caagattgaa gagcgaatca
    12361 acaacctctt ctttgaaaat gctggcttgg tcgagcaaga tgctacttac ttgtcaaacg
    12421 cccgtcacat ttccctgatt gaaaaagcag ttgaaagcct acaagccgtt aatcaaggtc
    12481 ttgagctggg gatgccagtt gatttgcttc aagttgactt gactcgtact tgggaaatcc
    12541 tcggagaaat cactggggat gctgctccag atgaactcat cacccaactc tttagccaat
    12601 tctgtttagg aaaataagaa aaatccatga tccttcattc ggtcatggat tttattgtct
    12661 ttattagtaa tctggtctta agacccctgt tacagttgcc ttagttgctt cgtagtcgcc
    12721 atctacgaca accttgataa tgcgtttggc atcttcttct ggtgctggaa caagaggtag
    12781 acgagtgggt ccagcttcaa atcccatata gttaagaatt gccttaactg gagcaggact
    12841 tggataagag aagagagcat taaccttagg aatgaattta cgctgaattg ctgcggcttt
    12901 cttcatatcg ctttctgcaa tggcagtaaa catctcgtgc atttcatccc catttgtatg
    12961 agaggcaaca gaaataaccc catccgcccc aaggttcatg gcatggaaag catctccatc
    13021 ctcacctgta taaatcaaga actcttcagg cttgtgctca atcaagtaag ccatattagc
    13081 caagctagta cattctttga caccgataat atttggatgg tcagccaagc gaagcatggt
    13141 ttctggagtc aattcgacaa ctacacgccc tggaatgtta tagataataa ttggtaggtc
    13201 agaagcatct gcaatagcct taaagtgctg atacatccct tcttgagaag gtttgttgta
    13261 gtaaggaaca atagcaagcc cagctgcgaa accaccaaat tccgctactt ctttgacaaa
    13321 ctcaatagag tcacgcgtat cattagtacc tacacccgca atcaaaggaa cgcgtccatt
    13381 gacaaccttt tgtacagccg caaacaactc caactcctca tcgtgggtca aagttggact
    13441 ctcagcagtc gttcctgcga gaagaattcc atccgtatga tgggccaata aatgctcaat
    13501 caaggctgga atagcatcaa agttaataga accatcctca tgaaaggggg taataaaggc
    13561 tgtaatgatt ttacattctt ttaaatcttg ataagacatg aaaacacctc tctatttcaa
    13621 agaaggagtt catctgaact cctaaacgat atgactattt taattcaaat ttcaattcag
    13681 ctgttggacg aaccaatcca cgttcatgaa gagtttcagc aatctgaact gagttccaag
    13741 cagcaccttt gagaaggtta tctgaaacaa cccacatgtg aattcctttt tctgcatcca
    13801 agtctttacg gatacgacca acaaaggtat cacgtgaacc aactgcattg atggcttgag
    13861 gatagatttg atgaactaca tcatcttcaa gaacagcacc tgggaaggat gcgatagctg
    13921 ctttgacttc ttcaattgga gccacttcct ttgtttcaat ataaactgac tcagagtgag
    13981 ctgacaagac tggaatacgc acacatgtcg cagatactgc aatgctatca tcttccataa
    14041 ttttcttagt ttccttggtc atcttcatct cttcgtacgt gtaatcatta tcagtgaaga
    14101 catcaatttg tggaagagcg ttaaaggcga taggataatg tttcttgtca ccacctgaag
    14161 gcaagatttc cgcatgcaaa tcacgtggtt tcactccatc attcaagacc tcacgaagtt
    14221 cacgttgtgt ctcaagaatt gctcccatac cagcacctga aacggcttga taagttgaaa
    14281 caatgatacg gtccaagccc catttttggc gaaccggctc aagagccacc atcatttgga
    14341 ttgttgaaca gttagggcag gcaatgattc cgttgtgggc atcaagtgca tgagcattga
    14401 cctctggaac aaccaaagga acatctggat tttgacggaa ataagatgta ttatccacta
    14461 ctaccacgcc agcttttact gcgtatggtg catacttagc tgatgtcgaa ccacctgctg
    14521 aaaagagagc aatatcaact ccttcaaaag ctgtttcagt cgtttcttca atcgtaatat
    14581 cttgatcttt aaatttcaat gacttacctg ctgaacgtgc agaagcaagg taacggattt
    14641 tatcgattgg aagtgttgat tcttccaaca tttttatcat ctgagcaccg acagcacctg
    14701 tcgcgccgac tacagcaact gtatatccca taaataacct ctttcggaat tttctaaaaa
    14761 tttctataat agaagtatta tactactttt tccatgaatt gcaaagcttt ttcatcattt
    14821 tttggaaaat aaaaatcccc aatcgctaga ctagggatta agaggcatct tcatgtgatg
    14881 agcaggttca cacaactcat caaggtccgc tcctgcgtta tgacctcctt atgctcaata
    14941 gtagcccgaa gactacctat cgactcatcg catctactat tctactaaag agaatgactt
    15001 ttgtcaacag acgaaactct ttatactctt cgaaaatctc ttcaaacttc gtcagcgtcg
    15061 ccttgccgta tgtatggtta ctgacttcgt cagtttcatc tacaacctca aaaacatgtt
    15121 ttgagctgac ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag caacctgcgg
    15181 ctagtttcct agtttactct ttgattttca ttgagtatta gttttattta cacaggtgca
    15241 taagaaatat attggaaaaa ttgggggcag acataacaaa aacccttgta aatcaagggc
    15301 ttttctgtct atttaatgct aattgccggg attgaaccgg cgacctcatc cttaccatgg
    15361 atgcgctctg ccaactgagc taaatcagct tacttaagaa gtatactata atcagaaaaa
    15421 cttgtcaagt ttccttagaa attttccata ggaaaaagcc aggtaagaac tacctagctt
    15481 atcttcttct atttacttaa atcaattcga cgaccaattt taccaataat aatcgctcca
    15541 ataatcaatg aagcaaattc accgattcct gttgtaaacc aagtaaggaa gaatggtaat
    15601 tctgctacaa tatttaactc tgcagcgata gtaaacatgg aaattgaaaa gaggattgaa
    15661 aagaagaaat gatcttttcg aatcaatccg ttaaagaggt aatccttgct atattttgca
    15721 aaaagccaaa cacctaaact gaggaatact aaggttgaac caccaccaac aaagacatct
    15781 agcagtccga agctaaagaa attagcaatc atacaaccga tggtaactcc gatgatgtac
    15841 ttaggattgt aaaaagccat aaagttcatc atttctgaaa tacgaaactg ataagcacca
    15901 tagctgatgg catttagggg cggtgtgaca gtcaaaacga cgtagatagc agcgacgatt
    15961 gcaatatctg caacatcacg aatagttaat tttttcatct tttctccttt ggcggttatc
    16021 cgcgtgtaat atgcttggtg aaagaagcta agcaccaagg gttgattcat tcaaccttac
    16081 tagtatagca caatagcctg ctttatgcta tacttaaagc atgaaaaaac ctattcaaaa
    16141 attttttaac aatgaaatct tagcctatct cttttttggc cttgcgacaa ctctagtttc
    16201 gattctctca cgactagtca tttatcaact aagtcatcag gaactccttg ctacggcctt
    16261 ggcaaatatt atcggtatct tatttgcctt tatcacaaat gatacgattg tatttaagca
    16321 aaaaaagaaa aatagactta tccgtttagt gaaattttct cttgctcgcc tttctacttt
    16381 tctgttagac ttgtttttaa cttttctctt tgtaacccaa tttcctcaca tcatagggca
    16441 attcgtaact gaaaacattg ataagataaa tgctattgaa acaataattg cacaaatatt
    16501 cattattatc atcaattata tcttgagcaa ggtctatatt tttagaaaat aatgctccat
    16561 ttatgagcct tttaattgcc ttctataatg atttaggata caatgaaaca cgaaacattg
    16621 aaaggaaaac agtatgttaa aaaatctaaa atcgttcttg cttcgaggaa atgttattga
    16681 ccttgctgtc ggtgttgtca ttgcctctgc ttttggtgct atcgttactt cacttgtaaa
    16741 cgacattatc actcctctta ttttaaatcc cgctttgaaa gctgctaaag ttgaacgtat
    16801 cgctcaactt tcttggcatg gagtcggcta tggtaacttc ttaagtgcta ttatcaattt
    16861 tatctttgtg ggtaccgccc tcttctttat tatcaagggc attgaaaaag cacagaaact
    16921 gactggcata aaggaagaaa aaactgccga aaaaaaacca accgaattgg aagtccttca
    16981 agaaataaaa gctctccttg agaaaaaata atcgattaaa aggatctagc gcaaagctaa
    17041 atcctttttt ctttactctt tgggtaactt gcctgctttt tcaagcattt ttttgataag
    17101 ataaggcatc ttaacattct cccgcccttt tttctcaatc agttttttca caaattctgg
    17161 catttgtaaa tcttcagatt cagccaaaat gtttttcgtc tcgtctgaag gaactaactc
    17221 atcaaaggtc tcttcttctg ggagaaattc cttaaactct tgattttcat tgattctaat
    17281 tgtattgacc aaagcatcaa tcaaacgaga atctgtattt ggcattggtg gacgatggta
    17341 gtttacccca aattcctgac ataagtcata acattccaca tcgttgtcaa acaagacctc
    17401 aatatgctca ctgatgaaac taataggtac aaaaatataa tggtctggat gttctgtctg
    17461 ttctctgaga tactccaaaa catctggttt aatccatgga ataccaatat cactctcact
    17521 ctgccaagtg ttggtatatt gttttgaact caagcccagt ttttcagcga ctagcttgct
    17581 attttcgaaa atttggtcta tataaggatc accaaagtcc aaggcaaaaa taggcacact
    17641 atgggctgaa aagatgactt taaagctgtc ttgctttact tcttctttta aaatcttagc
    17701 aatttcatct gcccaatagt ttaagagcgc ttcttcctga taccagtcct taatgaccaa
    17761 aaattgaatt tgtttgcttt ctaaaaattt ttcatagccc atgacagagt agaaagaata
    17821 atggggctcc aaaatcaagc aaatacactg ttcaattccg tctgcttcca tttgaccgat
    17881 cacatctgga ataaagggac tggaaaactt attagcaaag tagacactgt attcattccc
    17941 cagcctagct tctaccaagg caacctcttg acgggtaatt ttttgcagag gcgtgcctcc
    18001 aattcgtaca taattatcat agagagtctg aatctcgtgg tcttggggtc tcaccccacg
    18061 acgaatattt gtgaaaaaat cagctacacc ttcaaaggta atctcttctg gtgaaccgaa
    18121 ggtcatcatt aaaattgctt ttttcatgac tgcttccttg tgatgttttt atcaagttta
    18181 ttttatcatt aattcatcga taagtaaacg ctaacatagg gacattctca atcttctgtc
    18241 ttttgttttt ctcttctttc tatgatacaa tggaaaaaat aaattcaaaa ggagtttttt
    18301 tatgacttat ccaaatctct tggaccgctt cttaacctac gttaaggtca acacgcgctc
    18361 tgatgaacac tctactacta ctccaagtac acagagtcag gttgacttcg caacaaatgt
    18421 cctaattcct gaaatgaaac gtgttggact gcaaaatgtt tactatctac cgaatggttt
    18481 tgctattgga accttgccag ccaacgatcc gtctttaaca cgtaagattg gttttatatc
    18541 gcacatggat actgctgatt ttaatgctga aggagtcaat ccacaggtaa ttgaaaacta
    18601 cgatggtggt gtgattgaac tagggaattc tggtttcaaa ctcgatccag ctgacttcaa
    18661 gagtcttgaa aaatatccag gacaaacgct catcacaaca gatggaacaa ccttgctagg
    18721 tgctgatgac aagtcaggaa ttgctgaaat tatgacagcc attgaatatc taactgctca
    18781 tcctgaaatt aagcactgtg agattcgtgt tggttttggt ccagatgaag aaatcggtgt
    18841 tggtgccaat aaatttgatg cagaagattt tgatgtggat tttgcctaca ctgttgatgg
    18901 tggtccacta ggtgaacttc agtacgagac tttctcagcc gctggtgctg aattgcattt
    18961 ccaaggccgt aatgtccacc ctggtactgc caaagggcag atggtcaatg cccttcagct
    19021 agcaattgat tttcataatc aacttccaga aaatgaccga cctgagttaa ctgaaggtta
    19081 ccaaggtttt taccatctaa tggatgtgac aggtagtgtt gaggaggcgc gtgcaagcta
    19141 catcattcgt gattttgaaa aagatgcctt tgaagcgcgt aaagcatcca tgcaatctat
    19201 cgctgataag atgaatgaag aacttgggag caaccgtgtc actctcaact tgacagacca
    19261 gtactacaat atgaaagaag tcattgaaaa agatatgact ccaattacca ttgctaaagc
    19321 cgttatggaa gatctaggta tcacgcctat tatcgaacca atccgaggtg gaacagacgg
    19381 ctctaagatt tcctttatgg gaatcccaac tccgaatatc tttgcaggtg gcgaaaatat
    19441 gcacggacgt tttgaatacg ttagccttca gactatggaa cgtgcagttg ataccatcat
    19501 tggcatcgta gcttataaag gctaaaaaga cgaggtagct cagctacttc gcctttcttt
    19561 ttattctact ggtttttctt gatttccagt agttgtagaa gattctgttg tttcattttc
    19621 tgaagttgat tcagcaggtt tagaatctct tgtattgctt ggtttgtttt cgtcgctagc
    19681 agtttcaatg ttagattctg cagttgcgtt tggttggttc tcagcactgg tgttatcact
    19741 atttgcttca gcatttcttg ctggacttgt ttcttcactt gcgctagctt ttgactggat
    19801 ttgatgattc aaaactagaa tagcttttgt cgattcaagt aaagctgttt tgtctttact
    19861 cttagcagaa agttgatcta ataatgcatc caccttatca aagtccgcat cagatccatt
    19921 attactttct aaataagagt gaagcgacat gagaatatcg tagagttttt gatagagtac
    19981 aagtgtctga gaatcttgct cagcattttc cttttcttgt tgaagggcgc tagcgatacg
    20041 agtcaaaaca tcttttacct gactgtttac ttcatccaag tctgcatcag ccttgtttgt
    20101 ggcagctttt agattttcta cttcttctgc caaggattgt ctgattcctt cttcatggat
    20161 ttgttccaag agttgatttg ccttgctcaa aagactttct acttcttcct tgctatctgt
    20221 cgcagattat tggttgctat ctaccatgta ctcctaaaac aggagagtta taatccaaga
    20281 ttacaaggcc ttacagaaat aagaaatcca gataagacaa tgttcgtcca agacgctatt
    20341 cgcttcgcac aacagcacgg attcaatatg ctttaatttt aaagtttagg tgtcaagacc
    20401 tctttttagt gtgcccaaaa tttagagaag taatcaatca actaactttt atttttttca
    20461 aactttcagt aaactgacct aaagctaact caatctgtct ttgtagatgc ttctgctatc
    20521 agctagaagt tgatctactt ttgccaagac tgccttctca tcaaaagttc caggttgata
    20581 gttggattgc agggatggaa tcttgttttt caaagccgct tcatatccct tagtttgaac
    20641 cttgatgtag tgattgtggt cgccatgagg aatcacaaaa ccttctgaat cttcacttat
    20701 aattcgattg gcatcaaaac catgaccatc ttcttcctca tggtggacat gtagtgacgg
    20761 attacttaat acagaactag aagaacttcc tgcctcttcc gtgttagagt gtgatggggg
    20821 attgttaaga gatgacttag gaatatagtg atagtgatcc ccatgtctta ctatataagc
    20881 atcacctgta tctctgacaa tatcattagg gttaaagaca tatgtggctg ctaattcacc
    20941 tgccgacaag tcactctcag gaatgaaatg atagtgacca ccatgtggta ctatagtaga
    21001 ttgaaataga atatgagcaa attgataagg ggattttaaa gtaatttcta acaatgattt
    21061 agaaactatg atgtgctatt ctaaattcaa ctcactatat ataaccatca tcggtagtat
    21121 aacgtccctg taattttgct acagatactt ctgcactagc tcctttatcc tctttaccat
    21181 gttcttgttt ttggcgattg atttcatctt ttgttcgtac attttctgca tgagcttgat
    21241 ctttaaggta aacataatac tttccatcta ccttaatact atatcctccc ttaacctaac
    21301 tgacgatatc ttgatctttc ggctgatagt tgggggcttt cattaatggc tcttcactaa
    21361 agagcgcatc aaaaggaact ttaccattat agcagtgata atgatcgcca tgagaagtta
    21421 cataaccttg acctgtaatc ttaataacaa tttgttttgc ttgaattcct tctttttgac
    21481 taacctagtc tggagtcaaa ttttcagtct tcttagtgtc tttattactg tttacatatg
    21541 aaacacgatt tttatctgta ttggtctgtt agctatgttg gttcagagca taaacacaca
    21601 gacttaagga aaggataaca gcagatccag ctgctatata t
//
LOCUS       DAVKZI010000035        20712 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKZI010000035 DAVKZI010000000
VERSION     DAVKZI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20712
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.036"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            62..2146
                     /locus_tag="VXB18_001585"
     CDS             62..2146
                     /locus_tag="VXB18_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0382765.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKI
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            2156..2533
                     /locus_tag="VXB18_001586"
     CDS             2156..2533
                     /locus_tag="VXB18_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382766.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            2693..3835
                     /locus_tag="VXB18_001587"
     CDS             2693..3835
                     /locus_tag="VXB18_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0382767.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDFENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            3844..5058
                     /gene="thiI"
                     /locus_tag="VXB18_001588"
     CDS             3844..5058
                     /gene="thiI"
                     /locus_tag="VXB18_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0382768.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            5193..6006
                     /locus_tag="VXB18_001589"
                     /pseudo
     CDS             5193..6006
                     /locus_tag="VXB18_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            6028..6363
                     /locus_tag="VXB18_001590"
     CDS             6028..6363
                     /locus_tag="VXB18_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV0382769.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            6360..6767
                     /locus_tag="VXB18_001591"
     CDS             6360..6767
                     /locus_tag="VXB18_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0382770.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            6780..7946
                     /locus_tag="VXB18_001592"
     CDS             6780..7946
                     /locus_tag="VXB18_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0382771.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            8454..9947
                     /locus_tag="VXB18_001593"
     CDS             8454..9947
                     /locus_tag="VXB18_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0382772.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            9960..10487
                     /locus_tag="VXB18_001594"
                     /pseudo
     CDS             9960..10487
                     /locus_tag="VXB18_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285099.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            10488..11081
                     /locus_tag="VXB18_001595"
     CDS             10488..11081
                     /locus_tag="VXB18_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0382773.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            11141..11377
                     /locus_tag="VXB18_001596"
     CDS             11141..11377
                     /locus_tag="VXB18_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0382774.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            11374..11787
                     /locus_tag="VXB18_001597"
     CDS             11374..11787
                     /locus_tag="VXB18_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0382775.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            11905..12870
                     /locus_tag="VXB18_001598"
     CDS             11905..12870
                     /locus_tag="VXB18_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0382776.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            12904..13953
                     /locus_tag="VXB18_001599"
     CDS             12904..13953
                     /locus_tag="VXB18_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0382777.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYG
                     GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLVF
                     LLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQFACE
                     IAIKVWRNSLKFSII"
     gene            13982..17332
                     /locus_tag="VXB18_001600"
     CDS             13982..17332
                     /locus_tag="VXB18_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0382778.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENDFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(17838..18308)
                     /locus_tag="VXB18_001601"
     CDS             complement(17838..18308)
                     /locus_tag="VXB18_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0382779.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(18325..20598)
                     /locus_tag="VXB18_001602"
     CDS             complement(18325..20598)
                     /locus_tag="VXB18_001602"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0382780.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVSLPHKIELEKPQLNLVQPQGKAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFATLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNDRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYDLTVDLAQSMLTLPC"
BASE COUNT         6625 a         3491 c         4324 g         6272 t
ORIGIN      
        1 taaaatatga cttatgatat aacaaaataa agaaagcgat ttcaaaaaag gagggcgtta
       61 tatgttcgaa attagaaatt tgagtctctc ttttgcaggc aggcggttgc tagagccaac
      121 agatttgata tttgaaaggg gaaaagtata tacaatatat gggaagtcag gcgtaggaaa
      181 gtcttcttta ctgaataaaa ttggtttgct ctctgctacg gatcctagtg tttcttattt
      241 cttcgatgga aaagagattg atatcgaaaa taagaaatca gtctctgtct ttatagctga
      301 agaagttgcc tttgtatttc aggggcgaaa tctaataaat gatttgaccg tatttgaaaa
      361 tttaagacta gctttaaact tttatgactt gagtccagat gaaatagaaa gcaaaattga
      421 tacagtattg gcggatttac agatttcttc tttaaagcat gcttatccag aagatttatc
      481 cggtggtgaa gaacaacgag tggcaatcgc aagagcctta gttacaggaa agactctcat
      541 cttagctgat gaaccaacaa gttctttgga taaagaaaat agagaaaaag tctccgcctt
      601 gttaattgat ttagctcaca aatatcataa aattgtattg attgtttcgc atgatgaggc
      661 gatgattgca ataggagatg ttcagcttca ttttaaagac cataaattag ttgggaattg
      721 tcttattttg aattctgatg aagggataaa ggattctaag aagtggtcct cctgtttgtc
      781 gtcttctcat acgaagctat ccgttttgaa acatagaagg ccttttttac ctagattatt
      841 agcgtttttt atctctcttg tagttgctat agcagtaacc tctattaact ttcagtcctt
      901 atttgcagat aagtatcacc aactggtgaa caactcactc gaaaatggct tcttggtgat
      961 taatgattcg cttcatttac aaactacaaa agtgttggat gattttctca gttttgataa
     1021 agaggaaatc acctcaatta gcacaagtca gaatattcaa accgtcaatc cttatataga
     1081 gtttctctct ttgggtatga cgtttgataa ttcaaaagac tattcacaac ttcaaaagaa
     1141 ctttcagcca actttgacta ttgatggtca gaccagaagc ttgacaagaa atttttcaat
     1201 tcaacccttg tatcagacaa atacaacaca gaggcagata gagtattttg ataggagcaa
     1261 tgaaaaaggg atttatctat ctgagcaatt catttcagat gaaaaattac caaatatagt
     1321 ttcgggaact accgtgacac tgacttttta tattccaatt tctttatatg aatcaagtat
     1381 agagaaagag gggaatatat tgaaaggaga tggcgattta tttgtcaaag tggataaaac
     1441 atatcctgtt ttagggattg ttaaaaaaag ttatccgttt gaatattccc cttatgggaa
     1501 caccctattt atgaatattg ctgaaatgga agaattgcaa aatgaagcaa ttcaacagca
     1561 tcccatgacg aagatggctt tagatggttt tcctttgaaa tcatggatgc cgagtgcgat
     1621 tcatgtgtta ctaaaggata gcggtgctat tcctgaagaa ttgagtagaa taagagcaat
     1681 ctcttcacaa attactattt tatcatcata tgaaaactac gaagaattta ataaaggact
     1741 cacctatatc aggcaatttt taatgttgct atccctagtc ttactcatcc ttgtcatcgc
     1801 agtattgtcc tttgttttct ttttgctcaa tcgtcctcga cgctttgaag tagggatttt
     1861 aaaatctttg ggatacagta ctcaaaatat tgtttggctt ttcttaaaag aattaattgg
     1921 ttatggtaaa ataatttcga tattagcaag ttgtttactc gtcattcttt ccattttagc
     1981 aatgcaagtg cttaaattgg aaatttcaga tgtttttaaa ttctatctaa cttccgtttt
     2041 caccttaatt ggattatcag tctcagtact gataataagt ggcttactac ctatatacac
     2101 aacttgtagg caaacagttg tcgatactat ccgaaagaat ggatgaggtg atatcatgaa
     2161 acataagata atgaaaaaaa taatagtggt agtgtttgct atcccatggt taacattttt
     2221 aagtcaagta catgcagatt atgtaagtaa gtctagttct ttagacggtt atagcttggt
     2281 aggcttgaat gttcttaatg tgacttttaa tgcttctggc tattctgata cttatagtgg
     2341 cagtgtgtca aatatgtatt tcactgactg ggcttggttt cctaatacga taagtaatcg
     2401 ttccacttgg aaaagttcga ttccatatgg tcaacgcgca aatggtacag tccatatagg
     2461 tgtaggagta aattcgcctt ggggagcggt taatctctgg ggcggacaaa attacttttc
     2521 tttagatttt taacagaaat aatcaaagtt agatagaatg aataagaatg ctcttgatga
     2581 tggtatcaag agtattttat gttattcaga ttaatgcaaa cattgccctt tcttgtcgca
     2641 ggctccgttt catgatacaa tagaaggagt gattttagaa agcgtgagaa acatgattta
     2701 ctttgataat tcggcgacga ccaggcccta tccagaagcc cttgaaacct atatgcaggt
     2761 ggcttcaaaa attttaggaa atccatctag tctccatcgt ttgggagacc aggcaacacg
     2821 aattttagat gcttcccgtc aacagattgc agatttaatc ggtaagaaaa gtgatgaaat
     2881 cttctttaca tctggtggga cagaagggga taactggatc atcaagggag tagcatttga
     2941 aaaagcccag tttggcaagc acatcatcgt atcagccatt gaacatccag cagttaagga
     3001 atcagccctc tggttgaaag ctcaaggttt tgaagtggat tttgctccag ttgataacaa
     3061 aggatttgtg gatgttgagg cgctagaaga tttgataaga cctgatacga ccctcgtttc
     3121 catcatggca gttaacaatg aaattggctc tgttcagccc attgaggcta tttcaaaact
     3181 attggcagac aagccaacta tttccttcca cgttgatgcg gttcaggcgc ttgccaagat
     3241 tccgactgaa aagtatctga cagaacgagt ggatttcgcg actttctctg gtcacaagtt
     3301 ccacggaatc cgtggtgttg gttttatcta tatcaagtct ggcaagaaga ttacgcctct
     3361 tttaacaggt ggtggtcagg aacgtgatta ccgttcgaca actgaaaatg tggcaggaat
     3421 tgcagcgacc gctaaggctc tccgtttatc tatggaaaag ctagatatct ttaggagcaa
     3481 gactgggcag atgaaggcag tgattcgtca agcacttctg gactatccgg atatatttgt
     3541 cttttcagat gaggaagact tcgcccctca tattctgact tttggaatca agggtgttcg
     3601 tggtgaggtc attgttcacg cctttgaaga ctatgatatt ttcatctcaa cgacctcggc
     3661 ttgttcgtcc aaggctggga aaccagccgg aaccctgatt gctatgggag tggacaagga
     3721 taaggctcag tcagctgtgc gtcttagtct agactttgaa aatgatatga gtcaggtcga
     3781 gcagttcttg accaagctaa aattaattta caatcaaact agaaaagtaa gataggagca
     3841 ttcatgcagt attcagaaat tatgattcgc tacggtgagc tgtcaaccaa gggcaaaaat
     3901 cgtatgcgtt tcatcaataa acttcgcaat aatatttcag acgttttgtc tatctatccc
     3961 caagttaagg taacagcaga tcgcgaccgt gcccacgctt acctcaatgg agcagattac
     4021 acagcagtag cagaatcgct caaacaagta tttggaattc aaaacttttc ccctgtttat
     4081 aaggttgaaa aatctgtaga agttctgaag tctgctgtcc aagagattat gcaggacatc
     4141 tacaaggaag gcatgacctt taaaatctct agcaagcgta gcgaccacac ctttgaattg
     4201 gacagtcgtg aactcaacca aacgcttgga ggggctgtat tcgaagccat tccaaacgta
     4261 caagctcaaa tgaaaagtcc tgacatcaat cttcaggtgg agatacgtga agaagcagcc
     4321 tatctttctt atgaaaccgt tcgaggggca ggtggattac cagtgggaac ttctggtaag
     4381 ggcatgctca tgttgtcagg gggaatcgat tcccctgtag ctggctatct agcgcttaaa
     4441 cgaggggtag atatagaggc agttcacttt gccagcccac cttacacgag tcctggtgct
     4501 cttaaaaaag cccaagattt gacccgtaaa ttaaccaaat ttgggggaaa tatccagttt
     4561 atcgaagttc cttttacaga gattcaagag gaaatcaaag ccaaagcgcc agaagcctac
     4621 cttatgacct tgacgcgtcg ttttatgatg cgtattactg accgtattcg tgaggtacga
     4681 aatggtttag ttatcatcaa tggggaaagt ctaggtcaag tagccagcca aacccttgaa
     4741 agtatgaagg ctatcaatgc tgttaccaac actcccatca ttcgtcctgt ggttaccatg
     4801 gacaagttgg aaatcattga catcgcccag gaaatcgata cctttgacat ttcaatccaa
     4861 ccgtttgaag actgttgtac catttttgca ccagatcgtc caaaaacaaa tcctaaaatt
     4921 aagaatgcgg agcagtacga agcgcgtatg gatgttgaag gcttggttga gcgagcagtg
     4981 gctggaatca tgattactga aatcacacct caagccgaaa aagatgaagt tgatgacttg
     5041 attgacaatc tgctctaatt cagaaaatcc aaaagaatag cgaaaatcag taaaaaaagt
     5101 tagttttttc tctaaaaaca ggtaaaaaac taactttttt tatttttatg atataatgat
     5161 ataaaatttt gaatatagag agttttctga caatgaatca atcctacttt tatctaaaaa
     5221 tgaaagaaca caaactcaag gttccttata caggtaagga gcgccgtgta cgtattcttc
     5281 ttcctaaaga ttatgagaaa gatacagacc gttcctatcc tgttgtatac tttcatgacg
     5341 ggcaaaatgt ttttaatagc aaagagtctt tcattggaca ttcatggaag attatcccag
     5401 ctatcaaacg aaatccggat atcagtcgca tgattgtcgt tgctattgac aatgatggta
     5461 tggggcggat gaatgagtat gcggcttgga agttccaaga atctcctatc ccagggcagc
     5521 agtttggtgg taagggtgtg gagtatgctg agtttgtcat ggaggtggtc aagcatttta
     5581 tcgatgagac ctatcgtaca aaagcagact gccagcatac ggctatgatt ggttcctcac
     5641 taggaggcaa tattacccag tttatcggtt tggaatacca agacaaaatt ggttgcttgg
     5701 gcgttttttc atctgcaaac tggctccacc aaccgctata tcgagtgcca gaaactatcg
     5761 cctgaccaac gcatcttcat ctatgtagga acagaagaag cagatgatac agacaagacc
     5821 ttgatggatg gcaatatcaa acaagcctat atcgactcgt cgctttgcta ttaccatgat
     5881 ttgatagcag ggggagtaca tctggataat cttgtgctaa aagttcagtc tggtgccatc
     5941 catagtgaaa tcccttggtc agaaaatcta ccagattgtc tgagattttt tgcagaaaaa
     6001 tggtaagtta agaaaggaaa aaacgaaatg catattgaac atcttagcca ctggagtggt
     6061 catcctaacc gtgaaatgta ccttaaccgt tatggacatg gtgggattcc agttgtggtc
     6121 tttgcttcat caggtggtag tcacaacgaa tactatgatt ttggcatgat tgatgcctgt
     6181 gcttccttta tcgaggaagg ccgtgtccag ttctttaccc tatctagtgt ggatagtgag
     6241 agctggttgg ctacttggaa aaatgctcat gaccaagcgg aaatgcaccg tgcctacgaa
     6301 cgttatgtga ttgaggaggc cattctttta tcaagcacaa gacaggttag tttgatggca
     6361 tgatgacgac aggttgctct atgggagcct atcatgcact caatttcttc ctccagcatc
     6421 cagatgtctt taccaaagtg attgctctca gtggtgttta cgacgcacgt ttctttgtcg
     6481 gtgattacta caacgatgat gctatttacc aaaactcgcc agtagattat atttggaacc
     6541 aaaacgatgg ctggtttatt gaccgttacc gtcaggcaga gattgtgctg tgtacggggc
     6601 ttggagcctg ggaacaagat ggtttaccat ccttttacaa gctcaaagaa gcctttgacc
     6661 agaaacaaat tccagcctgg tttgctgaat ggggacatga tgtcgcccac gactgggaat
     6721 ggtggcgtaa acaaatgcct tatttcctcg gtaatctcta tttataaaag gagttaccta
     6781 tgaattacct tgttatttct ccctactatc cacaaaactt tcaacagttt accatcgaac
     6841 tagctaataa aggcatcaca gtcttgggaa ttggtcaaga gtcttacgag caattggatg
     6901 agcccttgcg caatagcttg accgagtatt ttcgtgttga taatcttgag aacatagatg
     6961 aagtcaaacg tgcagttgct tttctctttt ataaacatgg tccaattgac cgcatcgagt
     7021 ctcacaatga atactggctt gagctagacg caacactcag agaacaattc aatgtttttg
     7081 gtgccaaacc agaggatctc aaaaagacga aatataagtc tgaaatgaag aaacttttca
     7141 aaaaagcagg tgttcctgtg gtacctggag ctgttatcaa gacggaagca gatgttgatc
     7201 aagcagtgaa agaaatcggt cttccaatga ttgccaaacc tgataatgga gtgggagcag
     7261 ccgcaacctt taaacttgag acagaagacg atatcaatca cttcaagcaa gaatgggacc
     7321 attcaaccct ttatttcttt gaaaaatttg tcacttccag cgaaatctgt acctttgacg
     7381 ggctcgtgga caaggatgga aagattgtct tctcaacaac ctttgactac gcctatacac
     7441 cgcttgacct catgatttat aagatggaca attcttatta tgtgctcaag gatatggatc
     7501 ctaaactgcg caagtatggg gaagcaattg tcaaagaatt tggtatgaaa gaacggtttt
     7561 tccatattga gttcttccgt gagggggacg attatattac catcgagtac aataaccgcc
     7621 ctgcaggtgg ttttaccatt gatgtttata actttgctca ttccttggac ctttatcgtg
     7681 gctatgcagc tattgtcgca ggagaggagt tcccggcgtc agactttgaa actcagtatt
     7741 gtttggctac ttctcgccgt gcaaatgctc actatgttta ttcagaagag gatttgcttg
     7801 ccaaatatag ccagcagttc aaggttaaaa aagtcatgcc agctgccttc gcggaacttc
     7861 aaggagatta cctgtatatg ctgacaactc cgagtcgaca agaaatggat cagatgattg
     7921 ctgatttcgg acaacgtcaa gaataagaac tatcggatta aggaaattca ctcccttaat
     7981 ccttttgttt tgtctggtaa aaaataagag catcctaaca aggtagctat cataaaactt
     8041 gttcgataac tatttgaagc aggattaggt ggctagaaat tgaattttaa catttcaatt
     8101 tagtcatagt attgtgtttt cgtatcctta aatcagctaa aaggatccat gacgacacct
     8161 atacgatata gttttcagga taccaaacca gtctattaat actcaatgaa aatcaaagag
     8221 caaactagga agctagccgc aggttgctca aaacactgtt ttgaggttgt ggatagaact
     8281 gacagagtca gtatcatata cctacggcaa ggtgaagctg acgtggtttg aagagatttt
     8341 cgaagagtat aaaatattca ggtgacgcat agatatagtt aattgaagct ttgtttgaaa
     8401 tctgataaaa taatgatatt actaagtttt aaaaactaaa gaaaagggaa gatatgatta
     8461 caggcgaatt aaaaaataaa atcgatcagc tgtgggaaat tctttggaca gaaggaaacg
     8521 caaatccttt aacaaatatt gaacagttga cttatctctt atttatgaaa gatttggata
     8581 gtgtcgagct tggacgtgaa agtgatgctg aatttctagg gattccttat gagggagttt
     8641 ttccaaaaga taaacctgaa taccgttggt caacttttaa aaatatagga gatgctcagg
     8701 aagtttatcg tttaatgact caggagattt ttccgtttat taaaaatctc aagggggata
     8761 cagatgatac agccttttca cgatatatgc gagaagctat ttttcaaata aataaacctg
     8821 ctacgcttca aaaggcaatt tctatcttag atgtttttcc aactagggga ttagatgtag
     8881 attttgataa tgacaaacaa agtattactg atatcggaga tatctatgaa tatctgttat
     8941 caaaattgtc gaccgcaggt aaaaatggac agttccgtac acctcgtcac atcatcgata
     9001 tgatggttga gttgatgcaa ccgactatca aagatatcat ctcagatccc gctatgggtt
     9061 ctgctggctt cttagtatct gctagccgtt acttaaagcg taagaaagat gaatgggaaa
     9121 ccaatacaga taatatcaat cattttcata atcagatgtt tcatggaaat gatacggata
     9181 cgactatgtt gagacttggg gcgatgaaca tgatgctaca tggagtagaa aatccacaaa
     9241 tcagttacct tgactcgctg tctcaagata atgaagaagc cgataaatat actttggttt
     9301 tagcaaatcc tccttttaag ggctcacttg actacaattc aacctctaat gaccttcttg
     9361 caaccgtaaa aaccaaaaaa acagaattac tctttctttc tcttttcttg cgaactttaa
     9421 aaccaggtgg acgagcagca gttatcgtac ctgatggtgt cctttttggt tcgtctaaag
     9481 ctcataaagg aattcgtcag gaaattgtag agaatcataa gcttgatgct gtaatctcaa
     9541 tgcctagtgg tgtgttcaag ccttatgctg gagtttcaac tgccattctc atctttacaa
     9601 aaactggtaa tggtggtact gacaaagtct ggttttacga tatgaaagcg gatggtttaa
     9661 gtttggatga taagcgacaa ccgattagcg acaatgatat tccagatatt atcgaacgct
     9721 ttcatcatct tgaaaaagaa gcagaacgtc agagaacgga tcaatctttc tttgttccag
     9781 ttgctgagat aaaggaaaat gattatgatt tgtctatcaa taaatataaa gagattgagt
     9841 atgaaaaagt tgagtatgaa ccaacagaag tcatattaaa gaaaatcaat gatttagaaa
     9901 aagaaattca agctggcttg gctgaattgg aaaaattact caagtaggga ggtggctgta
     9961 tgaaaaaagt gaagttgggg gaagtttgtg agattttatc tggttacgct tttaaatcat
    10021 cacaatttaa tgataacaaa attggtctcc ccttaatacg aattcgagat gtagaaagag
    10081 gtttttctga tacctacttt gaaggaactt atcccgaaga atatcttatt aaaaatggag
    10141 acttattgat tacaatggat ggcagtttta tattgaaaaa atgggagggg gatttagcgc
    10201 tacttaatca acgtgtctgt aaaattaaaa ttacggataa aagtgtagat gaaggttata
    10261 tatcttggtt gattcctaaa tttttaaaag aaattgaaga taagacccct tttgttacag
    10321 tgaaacatct ttcagtagct aaaataaaag atatctcatt tgtattgcct aataaactag
    10381 aataaaagct aattgcaaaa aaactaaata cgataagtca aatttatgat tttcgtaaaa
    10441 ttcaatcaga aaaatttaac gagctcgtca aatcccgatt taacgagatg tttggggaaa
    10501 ataaaatatt tgaaagcatt gataacttat ttgatattat agatggtgat aggggcaaaa
    10561 attatcctaa atcagatgag ttgtttagtg aggagtactg tttattttta aatacaaaga
    10621 atgttactaa aaacggattt tcattcgata caaagcaatt tatcactaaa acaaaggata
    10681 aattacttcg aaaaggcaaa cttgagcgtt atgatatagt cttgacaaca agaggtactg
    10741 ttggaaatgt agcgtactac gatgaattaa taaaatataa acatttacgt ataaattcag
    10801 gtatggtaat attacgtccc aagacaccaa atctaaatca gaaatttatt atccatgttt
    10861 taaggaataa taattatagt cgagtgatat caggaagtgc tcagcctcag ttaccaatta
    10921 caaaattaaa aaaaatactt ctccccctcc ccccactagc cctccaaaat gagttcgcag
    10981 actttgtagt ccaggtcgac aaatcacaat tggcaatcca aaaatctctg gaagaacttg
    11041 aaactttgaa gaaatctctg atgcaggagt attttggctg atattctgcc attgtaatta
    11101 cggtaatgat ttgttataat acttcaaagg aggaaatcag atggtagtaa aaacaagaaa
    11161 acaaggaaat tcaatcacca ttacgattcc aagtgaattt aatattccaa gtggtgttaa
    11221 atacgaagcg aaattgttac caagtggtga gattatcttt actcctgaag aattggggca
    11281 gcaggtttct tatgtatctg atgatgcctt tgacttaaat ttagataaaa tatttgacga
    11341 atacgacgat gttttcaaag ctttggtgga aaaatgacaa tctatttgac agaaaagcaa
    11401 attgaaaaaa taaatgcttt agcaattcaa cggtattctc caaatgagaa aattcaaaca
    11461 gttagtcctt ctgccttaaa tatgattgtg aacttaccag aacaatttgt ctttgggaag
    11521 cctctttatc caacaatttt tgataaagca acgatactat ttgtccaatt gataaagaag
    11581 catgtttttg ctaatgctaa taaaagaact gctttcttcg ttttggtcaa atttttacaa
    11641 ttaaacggct atcgtttttc tgtaacggta gaagaagcag taaaaatgtg tgtaaccatc
    11701 gcagtagaag ctttaactga tgaaaaaatg acaagctact ccaaatggat ttctgaacat
    11761 tctgttagag aaaaggtcaa aaagtaacct agtatgctgg atttgaatga gcacaagaaa
    11821 ataaatgaac agacaatatt agaattctgt aatgcagaaa ctgatattgt ctctttttat
    11881 tgatgaataa gaaagtgaga aattatggaa tcaaaagtta caattatcat gcaagaaatg
    11941 ttacctcttt taaataatga acaattacta gcgttgagag agagtttaga acatcatcta
    12001 gtagacggaa aaaagcagca gaagtattcg aataataacc tgttgcaact atttattacc
    12061 gccaagcagg tagagggctg tagctcaaaa acaattcgtt attaccagag gacgattgaa
    12121 aacttgttta atgctattaa agagtctgtg acacaactca caacagatga tttaaggagt
    12181 tatttagcaa attaccagtc tgaaaaggat tgtagtaagg caaatttaga caatattagg
    12241 cgtatattgt cttctttttt tgcttggctt gagcaagagg aatatatcat taaaaatccc
    12301 attcgacgga taaagaaaat taagactgag caaaatgtga aggaaactta tactgatgaa
    12361 catttggaaa ttatgcgtga taactgtgaa aatttgagag atttggcaat aatagaccta
    12421 ctagcatcga caggtatgcg tgtaggggag cttgtacagt tgaatcgttc agatattgat
    12481 tttgaaaaca gagagtgtgt tgtctttggt aaaggaaaga aggagagacc agtatatttt
    12541 gacgctcgta cgaaaattca tttaagaaac tatcttaacg acagaaaaga tagtcaccct
    12601 gctctttttg taacgttagt tggaaaagtc cagaggcttg gaattgctgg tgtagagatt
    12661 cgcttaagaa agttaggaga caaactcggt atacaaaagg ttcacccaca taagttcaga
    12721 agaactttag cgactaaggc aattgataaa ggtatgccta tcgaacaagt ccaaaaactg
    12781 ctaggtcata gcaagattga cacaaccctg gcctatgcca tggtcaatca aaataatgtc
    12841 aagcattcac accaaaaatt catctcttaa aagcaaatcc cgatattccg aggaggtggt
    12901 tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatggcta tgcttttaaa
    12961 cctcaagatt ggtcatctga agggaaagag attatcagaa tacagaatct gactaaaact
    13021 tcaaaaggga taaattatta ttcgggtacg attgataaaa aatacattgt tgaagctggt
    13081 gatattctta tttcgtggtc gggtacatta ggggtttttc agtggtgtgg aagatccgca
    13141 gtgttaaatc agcacatttt taaagtggtt tttgataaga tagatataga taaatcgtat
    13201 tttaaatatg ttgttgaaaa aggtttacaa gatgctgtaa aacatactca tggttccaca
    13261 atgaaacatt taactaaaaa atattttgat aatattatgg tttcatatac aaatttggga
    13321 gagcaacaaa gaattgcaag tgagctggat ttgttaagca agctgatttt aaggagacaa
    13381 gaacaacttg aagagcttaa tctacttgta aaatcccgat ttaacgagat gtttggggat
    13441 cctttaaata ataacaagaa atttgcagta aaaacgggac aacagtgttt taaattttca
    13501 agtggaaaat ttcttgataa acatgataga gtttttgaag gttatcctgc ctatggtgga
    13561 aatggcattg cttggaaaag tcgaaaatat ttaattgata atcctactat catcattggt
    13621 cgtgtaggtg catattgtgg taatgtaaga actacccacg gtaaggtatg gataagtgac
    13681 aatgctatat atataaaaga atttaagaat tccgatttca atcttgtatt tttattagaa
    13741 ttaatgaaag taattgattt tagtaaattt gctgatttct caggtcaacc aaagataact
    13801 caaaaaccat tagaaaatca gaaatatatc ctcccccctc tagccctcca aaatgagttc
    13861 gcagactttg tagccctggt cgacaaatca caatttgctt gtgagatagc tataaaagtg
    13921 tggagaaata gcttgaaatt tagtataata tagctaaact atttgttaaa gtgagaaaaa
    13981 aatgggaaat tttagctttc ttttaaaaaa tgacgaatat gaatcttttt caaaaccttg
    14041 cattgaagct gagaatatga ttgctacatc aactgtggct actgccttta tggcgcgtcg
    14101 tgctttagag caggctgtcc attggatata tagtcacgat tcatatttag aagctcccta
    14161 tcgtgctact ctatcttctt tagtatggga tgatgatttt agggatatcg tagattctga
    14221 actccacaag cagatagttc tgttgattcg gtggggaaac catgctgctc atggtggtga
    14281 aattaaggaa cgagaagcga ttttagcttt gcatcatttg tatcagtttg ttaattttat
    14341 cgattattgt tacagcaatg agtttgtgga gcgttatttt gatgagaagt gcttaccact
    14401 ttcagcaaac atcaaatacc gagaaactcc acaatctatg ataaagttac aagacagttt
    14461 accagaactg cctgattttc atgaacagat ggctgctcag tccgtagaag ttcaagagac
    14521 ttatactgaa aaacgtgaga ctgcagcgca acggcaagat gtgcctttcc atattgatca
    14581 attatctgag gcagagacaa gaaagctctt tattgatatc gatctccgtt tagcaggatg
    14641 gatatttgaa gaaaactgtc gtgttgagat agccgttgat ggtctcaagc acggttcagg
    14701 aattggttac tgtgactatg tactttatgg taaaaatggg aaaattttag cgattgtgga
    14761 ggctaaaaaa gcctctgtca atccagaagt aggggaagta caggtcaaag aatatgctga
    14821 agctttggag aaacatatcg gctatcagcc aatttgcttt attacaaatg ggttgaagca
    14881 ctatatactt gatggtccga accgccgcca gattgcaggc ttttactctc aagaagaatt
    14941 gcaattagtg atggatagac gtcatcttca aaaaccgctt gaggatattt ctagtaaaat
    15001 tagggacgat atttccgggc gtcactacca aaaacatgcc attgcaagcg tttgtgaagc
    15061 tttctctaat catcgtagac aggcactttt ggttatggca actggggcgg ggaaaactcg
    15121 tacagcagtt tctctagttg atatcttatc acgtcataac tgggtaaaaa acgttctctt
    15181 cttagccgat agaacttcct tggttaagca agcctatgat tcgtttagaa aattactccc
    15241 agatctttcc gtttgtaact tcttagaaga taaagaagga gctcaatcaa gtcgtatggt
    15301 cttttcaact tatccgacca tgattggagc gattagtggt caagaagaag taaatcaacg
    15361 cccttttact gttgggcatt ttgaccttat cataattgac gaatctcacc gttctattta
    15421 tcagaaatac aagtccattt ttgattattt tgatgcaaga attgtaggct taacagctac
    15481 tccgcgtcaa gatttagata aaaacaccta tggattcttt aatttggaga atggggttcc
    15541 aacatatgca tatgatttgg aagaggctgt taaagacgga tatttagtag cctatcattc
    15601 tatcgaaacc aaactgaaac tacctacgga tggtctacat tatgatgatt tgtccgaaga
    15661 agaaaaggaa cattttgata gcaaatttga agacgatagc tgtgaaaaag atattgatgg
    15721 gagtgtattt aattccttta ttttcaataa aagtacagta gaaattgttt taaatgaact
    15781 catgacaaga ggaattcaga cagcctcggg tgatgaaatt ggtaaaacta ttatttttgc
    15841 taaaaatcat gatcatgcgg aatatatcag aggtattttt aacaaccgct atcctgaaaa
    15901 agggagcgac tatgctcagg tgattgatta tagtattaag cattatcaga ccttgattga
    15961 tgattttaaa attaaggaga agtatcctca aattgcgatt tctgtcgata tgttagatac
    16021 aggtattgat gtaccagagg ttgttaattt agtcttcttc aagaaagtac gctctaaaac
    16081 taagttttgg cagatgattg gtcgaggaac ccgtctatgt aaagatttat ttggacctga
    16141 gcaggataag gaaaacttct tggtatttga ttatggggac aattttgatt attttcgtgc
    16201 agatccaaga gatggagagg gtcgtcacat tgtttcgctg actcagcgtt tatttaatat
    16261 caaagtggac ttgattcgag aacttcaggg actccaatac caagaagatc agtttgcgag
    16321 agcataccgt cagcagcttg tctcggaact tcaaggtcgt atagagagct taaatgagtt
    16381 ggacttcagg gttcgtatgg ttttagatac agtttatagc tataggaaat tggaaagttg
    16441 gcagaatcta actgctgtta caagtgaaac cattcaaaaa aatctctctc tgcttttatt
    16501 tgatgaagat aaagaagatg agatggcgag gagatttgat ttgtggttgc ttcatattca
    16561 gttggggcaa ctgacagcta aatcttccac tgttcatatt tcccaagtga tgaagacggc
    16621 tagagctctt tctgctattg gcaatatccc gcaggttttt gagcaggctg aaattatcag
    16681 gaaagtacag gagcctgaat tttggaaaga agttaacttg tctgatttgg aaaaaattcg
    16741 tcttgctatt cgagatttat tacagttttt ggataaaaca gaccgtaaac cctactatgt
    16801 taactttgaa gatcgtatac tctccactgt tcacgagacc acagcatttt tgcaggtcaa
    16861 cgatcttcgg tcttacaatg aaaaagttga gcattatttg aaaactcatc tggatgagga
    16921 gtccatttct aagctatacc ataataaaaa gttgacatct gatgatatgc ttgcacttga
    16981 aaaattgctt tgggaaaaat taggtagtaa agcagactac caaagtcatt atgaaaataa
    17041 ggcaattccg agattggttc gtgagattat tggcttagat agagagtctg ccaatcgtat
    17101 tttttctaaa tttttgtcgg atgagaatct taatgccagg cagatttcat ttgtaaaatt
    17161 gattgtagac tacattgtag aaaatgattt tttagagacg aaagtgttaa cgcaagagcc
    17221 gtttaaatct tatggttctg ttcaactact cttccaacac caactaccag tacttcgtaa
    17281 tattgttcaa atcattgaac ttatcaataa tcgagctgga gaagcggctt aaattctaaa
    17341 gtgattgcca tgctgagact catttaaaat taaaaagagt agaaatttat gctatatatg
    17401 agaagtttta ttaggaagaa tgtcatcgtt ttcctagaat acagtatcag ttgttaagtg
    17461 gttgataaat ttcaaagtag atacttgtac cacgatgttt gttgatcgag ttattaacaa
    17521 aagagctact ttgattttaa agaaatagaa aacaaaaagc cgagcaagaa ttcaattgca
    17581 ggagaaaatg aaataatact caatgaaaat caaagagcaa actaggaaac tagctgcagg
    17641 ctgctcaaaa cactgttttg aggttgtaga tggaagctga cgcggattga agagattttc
    17701 gaagagtata aatcttccta ggataaagca aaacgcatag tatcaagggt tttcaacact
    17761 tgatactatg cgttttctga tgttaaagac tttctaccag gttttttaaa agcataattg
    17821 ttagttgtag tcatttatta ttcttcaaag aaaaatggtg gggcgaattt tttcagttct
    17881 tcaaagcact tttgagcagt atctgcatct tcacagatga taagacagac atcattacca
    17941 caaagggtag cgatagcgtc agggaagctc aaagtatcaa tgatagaacc aaaggattga
    18001 gccagtccag gaagggtttt tagtaggact tggtgttgaa ctgggcgcat ccagacaagg
    18061 gcgtcttcca tgtagagttc gagacgtttt tcccattttg agatggaacc attgttaaga
    18121 acataataag cgctatcttc ttcgcggact tttgataggt tcatattttt gatgtcgcgt
    18181 gagagggttg cctgggttac ttgaatgtcg ttctcagcaa gaagggcttg caactcagcc
    18241 tgtgtatgaa tcttgttttt tgtgataaga gcgcgtataa gttggtggcg gtgttctgat
    18301 ttattcataa taatgtaact ccttttagca aggtaaggta agcatggact gagcgaggtc
    18361 gacagtcaag tcgtagtctg tattgtcacg gatggtgatt tcaaagtcag tagtatagag
    18421 gactaaacgg agagtgtctc cttcttttag cttgtaaata gttggctgca gttcaaattg
    18481 aacgtccatc cattcatctg cagtaatatc ctctactaac agtaaatcat ttctattttg
    18541 taaattaagg taaccttttg tcacgactcg ttgtgcctct ggtctaaatg gcaattcaca
    18601 gagattttcc aacatgtgat agcgaccgtt gtcaatggtt ctagcactta aaatagctgg
    18661 ataaggttgt aggtatttct tttgcccaaa ttctagcagt tgggcagata agagcccctt
    18721 gtttgtactg gatttgatac gaagattgag ctgagcgcga ccgtttaggt ggagatcttt
    18781 agtcacagga aggttaatag taatctgatt ggctttccct tgatagagct ctgtattgaa
    18841 ggtttggtat gtcttaccat agcgctcaaa atccttatct gggtactggt tttgaatagc
    18901 ttgctcttct tgaccaagtg agaaggtttc acagttttct tgcccaccga agttatcaag
    18961 tgataaccaa gtctgtggag ctgtattgtc ctgccagata acagtaggaa gttgaaagtc
    19021 tgtttcctgt cctagtaatt tcttggtcaa taaggcattt atggactcac ggaagtcaat
    19081 tgattgccaa ttgttcatgt aaacatgagc accattatgg aaaaagagat gcttgtgtat
    19141 atgagtagga agagcatgga acatctggta aacatgaagt ggtttgacat tccaatcctg
    19201 agaaccatga gtaaagacaa cctctgcctt tactttatgg gcattgagca gataattgcg
    19261 gtcatgccaa aactgattgt agtccccagt ttttcggtct agctgagctt tcactttttc
    19321 taagtcagct tggtgagctt cattgccacg gatatagtcg ccagctaaga gattacgaga
    19381 ataggttaac tcagcaaggg agtcaaagtc ctcacctgga taaccacctg ggctagtcac
    19441 cagaccgttt tcacggtagt agttgtacca tgatgaaatt cctgcctcgg caatgataac
    19501 ttctaaacca tcgactcctg tagtcgcaag accattggac atggtaccta gataggaaag
    19561 tcccgttgta gcaacttttc cgtttgacca atcagccttg acttgacgct ggcgcgtgtg
    19621 atcagtaaag gcacggcaac ggtcgttaag ccaatcgatg acatttttat aagcctcgat
    19681 ttgctggtag tctccattag tcatgaaacc tgtcgagtct ttggtaccaa cacctgagac
    19741 atagagagtg gcaaagcctc tcggaaggaa gtagtcgttt agtgtatagc tagagttgat
    19801 gtgagttagc ttttcctcag cctctgctac aagctcagct ttaccttggg gttggacgag
    19861 atttagttga ggtttctcta gctcaatctt gtgaggaaga gaaacctcaa gctcgccctc
    19921 catcttgtag agagccttgt cactagcctt gtcattggtt ccctgatgat aagggctggc
    19981 tgtcatgatg gcagggattt ttccatcaaa acgagggcga ataatgctaa cctttactag
    20041 gtctggtagc cctttttggt cagtatcgac acgagactca acgtaaacga cttcacgaat
    20101 gacatcctgg ctagaaaaag tagccaaact cttgccgtta aagtagtggt agtcattatc
    20161 ctccggaata agaccatcac taacaagttg gtcgataaga gtatttcctt ttttggtgcg
    20221 agtattgagt aactgataga gattttcaat caagtcacca tatataatgg gaaatccagt
    20281 ttctttacga aaaacgtcac tatcttcgaa gtcaaccaaa taagaaaagc ctaaaagttg
    20341 aaaagcaaca gtataaaaaa tatctgctgt cagttcatct tctgattgaa aaaatgtcag
    20401 caggtctgtt tttttatcag ctgctaggat ggaaagtggg tagttggtgt cttgataagt
    20461 gaaaaagaaa cgacgtaaaa aggtttcaag tgagtctttg tgattggctg tattttgtaa
    20521 atcaaagcca cattttttta gttcagataa gacattttct tttggaaaat tgatataact
    20581 atattgatta aaacgcatag aacctccata tagaatgaca gttaaggtta ttatatcaaa
    20641 aaaaaagcag aaagggaatt gttaacttca aaaggaaata atccaataaa aatgaataaa
    20701 gtactaaatt ca
//
LOCUS       DAVKZI010000036        19990 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKZI010000036 DAVKZI010000000
VERSION     DAVKZI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.037"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            176..358
                     /locus_tag="VXB18_001603"
     CDS             176..358
                     /locus_tag="VXB18_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0382781.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            303..1009
                     /locus_tag="VXB18_001604"
                     /pseudo
     CDS             303..1009
                     /locus_tag="VXB18_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1079..1441)
                     /locus_tag="VXB18_001605"
     CDS             complement(1079..1441)
                     /locus_tag="VXB18_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382782.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(1731..3611)
                     /locus_tag="VXB18_001606"
     CDS             complement(1731..3611)
                     /locus_tag="VXB18_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0382783.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWSVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLQTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDHVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPNNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTNFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3605..4474)
                     /locus_tag="VXB18_001607"
     CDS             complement(3605..4474)
                     /locus_tag="VXB18_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0382784.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGVSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAATGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4558..7203)
                     /locus_tag="VXB18_001608"
     CDS             complement(4558..7203)
                     /locus_tag="VXB18_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0382785.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7294..8574)
                     /locus_tag="VXB18_001609"
     CDS             complement(7294..8574)
                     /locus_tag="VXB18_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0382786.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDEIF
                     VVATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8745..10829
                     /locus_tag="VXB18_001610"
     CDS             8745..10829
                     /locus_tag="VXB18_001610"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0382787.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDMATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTSFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(10869..12548)
                     /locus_tag="VXB18_001611"
     CDS             complement(10869..12548)
                     /locus_tag="VXB18_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0382788.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            13303..14532
                     /gene="arcA"
                     /locus_tag="VXB18_001612"
     CDS             13303..14532
                     /gene="arcA"
                     /locus_tag="VXB18_001612"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0382789.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPVYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14590..15606
                     /gene="argF"
                     /locus_tag="VXB18_001613"
     CDS             14590..15606
                     /gene="argF"
                     /locus_tag="VXB18_001613"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0382790.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            15771..16718
                     /gene="arcC"
                     /locus_tag="VXB18_001614"
     CDS             15771..16718
                     /gene="arcC"
                     /locus_tag="VXB18_001614"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0382791.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16927..18438
                     /locus_tag="VXB18_001615"
     CDS             16927..18438
                     /locus_tag="VXB18_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0382792.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18460..19791
                     /locus_tag="VXB18_001616"
     CDS             18460..19791
                     /locus_tag="VXB18_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0382793.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5710 a         4476 c         4103 g         5701 t
ORIGIN      
        1 aagtcaagga aaattaaccc actttaattt cttttttaac ccgtgtttaa aaaagaaatt
       61 aaagtgggtt aaaaaagaaa ttaactgagt aaaaactctc gaaattcaat tcgctatatt
      121 atcactcaac ttgaacaaat accagaacca caaaaaacag atgcaaagga aaaatatgga
      181 cttaaaattt gaaggggttg atttagaata caaaaaagct aaaaacaatc ttccagagtc
      241 tttctgggaa acctactcag catttgcaaa tacaaatggc gggaaaataa ttctcgggat
      301 agatgaaaaa aacattgaca cctaccaaag agtcaataga ctccctgcga aattatgaag
      361 caagtaaaca attaactgat acacgattta agcgtcttgt tggtgttcag cgcacgactt
      421 ttaaagagat gttagctgta ttaaaaacag cttatcaact taaacacgca aaaggtggac
      481 gaaaacctaa attaagccta gaagaccttc ttatggccac tcttcaatat gtgcgagaat
      541 atcgaactta tgaacaaatt gcggctgatt ttggtattca cgaaagcaac ttaatccgtc
      601 ggagccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca agaactcctc
      661 tcagttctga ggacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa
      721 aaagaattag cgaatgattc tggtaaaaag aaatttcacg ctatgaaggc tcatgaagat
      781 atatcctcaa gcacaaactc cacgtaaatc cagcaaactc aagccgctaa cagctgaaga
      841 taaagcctgt aaccatgcgc tatctaagga gagaagcaag gttgagaaca tctttgccaa
      901 agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat catcgtaaac gcttcggatt
      961 acgaatgaat ttgattgctg gtattatcaa tcatgaacta ggattctagt tttgcaggaa
     1021 gtctattgaa atactaagcc tacacagact gattccaatt gttttttaga tttcaatttt
     1081 accattcttc atagtcaaaa ccatcataat ctggatattg ttctggcgac gttccaaccg
     1141 aacgtacgag ataagcttct tcgtcctctg tctcgatttc tctcagtact tggcattcaa
     1201 aacgccattc atcaccgaag tcgaaaataa acttaaattt ttgtttgaca cttaggctat
     1261 ccagatagac attttctgtg taacgttctt caacatcgtc actaacaaag ctaagaaagt
     1321 aagaatctgc atgactccac tcaacattat ccatgaaaaa tgcgtgagca tgatcatttg
     1381 caaaatcgaa actccataaa atcacatctg ctagttccgc taacgttttt gtttttggaa
     1441 tctatatatg tcggtagcaa ccttttttaa tttgacggaa atgatccaag cttctacaga
     1501 tgctggcttt tcagcttcta tttcttgttt tactaatttt aactgtagca tttgaaacca
     1561 gataattctt ctgtttcacg cgaaacaccc tgcgccaagc aaggtgttct tgtttttata
     1621 ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa aacactgttt
     1681 tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta ttaagtcgta
     1741 taaatcgtcg aagctgtcgc aatggtatgc cactggttag ctgtagttgc tgcgaaatcc
     1801 ttgtctgcgt agaagttagt aaatggtagg atttcaactt ccagctcgtc gatgcggtca
     1861 agctggccag ccagataaac ctcgatacgg ctttctgctc gtttgatgcg ttgcaagagt
     1921 ccgcccatac ggatgtcaac tgtatccaaa ccaaagacct tgttttcttt cagccattgg
     1981 tgactaaaga gggcatggaa gtcttcaatt tggcttctaa gttctggtaa ttcttgtctg
     2041 gcgatttgtt gtaaactttc tttatcatcc gcttggtagg cctgacgaat gcgtcgtccc
     2101 acatctactt tgctacttaa aatagcattc aactgggcct gagtttcaaa gagataagca
     2161 tagtttccag ctttttcttt aatgttagca agcgtctcag cagcctgagc gaagtgcggt
     2221 ttgtcctgtt caggtgtcat gtgttgatca agaatcggac aaagaacatc ctgataaaaa
     2281 acatagcggt tgggattgat accgctgaga ttgcctggta ggtctggtaa gaggttggca
     2341 aggtcaatct gcataaaatc ttcaaccgtt agaccagtat tggtcttgaa atgcgcagac
     2401 aaactatcta ggtcattgcg atagctgagt tctgcccaga tttgcaagct tggtaggata
     2461 gagaactggg cagtttcacc accattgtct ccccaacccg ttacgatgac ttctttaatc
     2521 tgattggcac ggcaggcttt attggcctcg atagccacta gacggctgaa atggttattg
     2581 ggtgtgaaac caatccactt ccaagctccc cctgcaaatg caaggtcatg gctaatcttg
     2641 tgatggttgc ggaaattacg gttgtatttt tcctcgctat cctgataata atcccagtaa
     2701 accagagtca catggtcttt gagacggtct aggtagacac gagtttcttc tggaatttcc
     2761 acatcacggt cgtactggcc atccgctgac atgagtttga agaacatatc actccacatc
     2821 tggcagtgga aaccatattt gtcagcaata tccagcacgc gctccaagtg ttggcacatg
     2881 aggagactac gatccacaac accgttcaat atcaagtaac gtcccaaacc aaccaagtgg
     2941 gcttcgtcca tcccgatatt gaccttgcga gtttgtagtt tagacagagt ggcaaacatg
     3001 ccatcaatca ggtcataaac cttttcttcg ccgataagga ggatatcctc cacatcacgg
     3061 agctcctgaa cttctttgac actccattta acaaaggccg acaagtgggc caaggtctgg
     3121 atgcatggta caaaggtcat gtcaaactgt tgagcatagg cttcgatttc ctgcaactcc
     3181 tctgctgaat aagctccacg gaaatagcca aagtaaggct gcccttcaat ctggtaagtg
     3241 tcttccatgt aaagttcaaa ggttgagtag cccatgagag ccaagacctc aatcatctgc
     3301 ttggcagaag ccacattcag caccgcattt cgagaacagt caaccatgta agccaaatct
     3361 tcgtaagctg cttgttcctc aatctctact ttatcagctt ctgctagaac tgttaccaac
     3421 aaggataagg cacgataaag ttggtgaggt ttgcggtagg tcaattgata gtgaccttcc
     3481 tcaccctcga tagagataga ggcttggtca gactgagtga cagccacttc cacatctggt
     3541 agagaaatgt gaccttttaa aacctcaata gcttgcgttt gtttgggact aagtcctgta
     3601 aatcttacca ttgcttttcc tcctgtagcc agttgacaag ggcaccgtag agattggcat
     3661 ctgcgtgata ggtgcaggtc tggataactg gtgcgaccgt gtattcttcg taggcatcga
     3721 caaagtcttc aacagccttc ttaacacctt ggataaaatc tggattttga ctgatagagc
     3781 cacccagact gatgacatct ggatcgatca gatactggat attgagcaag ccttgcgcca
     3841 gattgcggtt catgcgctca atggcttctt gacaaagagc attaccagtt gcggcctctt
     3901 ggtaaatctt gcgaccgtcc caatcagtat gaccagattt ttcaatcacg tatcgtacca
     3961 tattcccagt tgatgctagt tgcgaccagt tattaagttt ttcagcaggg gcaagggttg
     4021 tcatgtaacc aaattctcca cccagaccgt ggcgacctcg atgaagtcta ccattgataa
     4081 tcatggctcc gccaatccct gtcccaatca cgacacaggc tgcattttca agctctggat
     4141 gagctagtag ttcactgact ccaacgcagt tggcatcatt ttctaaatgg acaggtagct
     4201 gataagagct aagcgcctca taccaagaaa agccatggat gtagggcacc gcactgaagc
     4261 catcaatcac acctgtctct tgattgaccg cacctggaac gctcatagca atcccactgt
     4321 aatcctgttc tgacaagcgt tgatctagcc acgctagtaa atcctccaag ttttcaggcg
     4381 ttgaaatact tgtcttatcc agtattttcc catcaggagt cagactggca aacttaatcc
     4441 cagtccctcc gatatcaatc gttgcaatgg tcattgtttt taccataaaa aggggcgaat
     4501 cagcagttag ttcttacttt ttcgcccctc ctttcttttg atgtttactt tttgaaatta
     4561 aatttcttct tttttgatga attctgtacg aatctcttgt ggagccaata gtcctgaatg
     4621 aactggatat ggtcgctcaa gtaagtcaag aatggtttgt tgatgttctg atatgcgcac
     4681 attttcttga ctcatattat agtaacggag gacatagcct tcttcatttt ccgccacttt
     4741 aaaggctgtt ggacaaactt gcggtatgct gagaacagaa tggctcaaga ggctaccagt
     4801 cgcaaccacg cttccttcct gtctagcaag ctgaaggctg gtaaacggtg tctgcaaggc
     4861 tttggcacga cgataggctg agaagcgttc ttgggcttgg tggcattcaa gtgcaaactc
     4921 gacttcaaac tcccgcaagc attgtgcttc tggcgttggg aagtagcccc agtcacctag
     4981 ctcacctgat gcacgcaaaa tggtcacggc aatggtgtta tccccaagga tttcgtattc
     5041 attcaatccc ttgttggata cagtcacacc tttttcatcg tcatacagac taacaaaggc
     5101 ttgttggtgt tgaggatttt caggattttc ccatgaagct gctggtttgt ttggtcgtgt
     5161 caccacctca tagatgcttt cagaatcatt gcttggacgc gtgttatgag tcttgaccaa
     5221 gagacggata cggtgatcct tggcagtgtt ggtaaagcga gtcttgaagc ggatttgtgg
     5281 attgtcaacg aagacagtca actcagtttc cagaggaatg tttgtcaatt cttctgaccg
     5341 tccagcctca cgcttcataa actcgatgat accttgttgc tcttcttcta gcttttcatc
     5401 cgcactgaca ggcacggtca attcatgttt gagcaagatt ttagcatagc aagctgtgtt
     5461 ttccaagacc tcgtggccct taagctctgc aaagattggc tctgttcctt ttggttggaa
     5521 atagatatac tcgtttccga tgtcaccccg gtcttcgaag cggataaagt cttcataggc
     5581 ttcgtgagtt gtcttgtcat agactgtgat gttgtcatcc acactcaccg ttacgaatgg
     5641 tgtatcaatc actccgtttt ggtaaatacc ctcacggtgt tcttgttttc cttccagcaa
     5701 ttggaaggtt gtccaagaaa gcggcgctag gtgaactgga atggtcacgc gcacttgacg
     5761 agcaatacga gcttggcgga acttgtcttt tggtaaatca tactcaaaat tagctccgag
     5821 gtcttcgatt gtagcctcta caggacgacc atccaagtcc tccacacggt aacttggcaa
     5881 gataagagca gccatctttt tgtagccttc tgttgggtgc aattccttga aatcacaagt
     5941 cgccacatca atcactgtgc tgacagtatc gaccttatca tgcaagcctg tgttaatgac
     6001 agtaaagaga tagtcacttt gagccttatc cgtagcaatt ttacccttcc actcgttgag
     6061 caaattactt ttaacaaagt ttcctacttg gttgaccttg gcaaaacgcg tttccatctc
     6121 gcggtgaact tcgtccacgc tacagccaca gatactatca tgtggcgcat tctgcaaaag
     6181 tgttttccaa gcataggtca actggtcctt gtggttgtgt ccaccagtga taatagtcaa
     6241 gggttctacc acttgctcta ggaggttgct attttcttgg aaggcttgtt ttaggtaaat
     6301 gcgggatgaa gaagtgttgg caagtgtgta ccagccatct gtttcctgac tggtcaactc
     6361 acctgtaaca gttgataagt gttcaggaag agcaccttct acagcttgaa catattcatc
     6421 aaaagaacta tgaacaaaga ttacatccgg gaagagttca tttgccacac gaatggcttc
     6481 gctcagattt ttctgtacag gctggtggtc acagccgttc atcatcaacc attggttggt
     6541 cgaagcgtag gcacgcacat ctgacaattt ttgtttccag aaggtcaagg cctcatcttt
     6601 gtcaactggg atttcattcc cattactgta ccagttggca aagagaatac ctaaaacacg
     6661 actaccatcc acaccctgcc agtacatttc tgaaaactgg gatgtaaact gctcatcttc
     6721 aaggacttgg ttgtcaaatc caatcggctt cacaccacga ccaaaggccg ccacgtgaat
     6781 gcctgatttt tgaagaattt gaggcgcttg tcccatattt ccaaaggtat ctggaaagta
     6841 gccaatctgg gttgatttac cccatttggc agcttcttgt tgaccaatca aggtattgcg
     6901 gacattggct tcacttgaaa tcaaataatc atcctgcaag atgtaaaagg gaccaatttt
     6961 aagcttgccc tcgtcaatgt agcgttggac cttgtcgcga ttttcagggc gaatttgtaa
     7021 gtagtcgtca aggacaatag tttgtccatc caagtggaaa ctcttgaact cagggtcatt
     7081 ttcaaagaga tcaaagagat tgtcaaacaa ttccaccaac tgcatacgat gactttcaaa
     7141 aggcaagtac cactcacggt cccagtgact atgtgagata atatgtacaa caacattttc
     7201 catgaagtaa aacctcattc taaatttaaa ttttaacgtt ttaaatgtaa acttgtgatt
     7261 ctgataagaa tcggttgagc taaagcgagc cccttagcga atatccaagt aatctaagac
     7321 caactcacag aacatcatgt tagcccagga gaaccattca cgagagtaga gagttgggtc
     7381 atccacgtgg aagctttcat gcataagacc tgtaccgcca tcgcaggcaa ccagctgatc
     7441 cagcaagaag tttttctctg ccttatctct tgttgtcaag ccttggatag aaagggcgat
     7501 tggccagata tagcgataga aggtatgaga acttccgaga ccgctagcgt attctccttg
     7561 gtagaaatat ggattttcag agctcagaat ggtacggcga gtagcttgat acacttcatc
     7621 atcgaccgaa cagtagccca gatagggcgc agctagtaga cttggtacgt ttggatcatc
     7681 cataatgctg gcatttccta ggccatctac ttcaaaagcg taaatctttt cgcccttgct
     7741 gttggtggtg taagcgtagt tttcgattcc ttcttggatt tcatcctgaa gacgcttggc
     7801 atcagcaata acactctggc tatcagctag gtttaatgct gcgaagattt cttgcacata
     7861 acccaagact actacagcaa acatatttga cggaatcaag taactatact ggcaacagtc
     7921 atcactcgga cgaaaggctg accaagtcat tcctgtcact gcaaaatcag gtccaaagcc
     7981 atcatttacc aaggtgtctt ccttacggtc cgtatctcgg acaaaacgat aaggagagtt
     8041 cttgtggtct tgttcaactg tccatagatg gagaatttcc ttagtcgcta cgacaaaaat
     8101 ctcatcaaac tgaccagtct cgccagtctc tttccagagg agataagcca actgcaaagg
     8161 atagcaaagt gaatccacct catacttgcg ctcccagatc cagccgttaa ggtctgtgtg
     8221 gtcagtctcg tggtgccctt tccagttctc ctcaatgttg aaggagttag catagggatc
     8281 cttgagtacc aaggtcatct gacgtttgac caaacctgca atggtctgac gcaggagggc
     8341 atctctttta gctacatgaa ggtagggtct gagttgggct gtcgaatctc gaagccacat
     8401 ggcaggaata tccccagtca agacaaaagt tgaaccatct tctaagattt caaccgtatt
     8461 gtccaaggta tcggtgtagc aacgctcgaa aacatccacc cactctggat ggtccttagc
     8521 ccgctctgct acttcatcta gccattctct aacaatttct ttcgaataaa tcatcgtgca
     8581 attccctctt tcaaacaagt ttcatgttca gtatatagct tttgagacag aaaatacata
     8641 cacaaatgat agtcattttt ctacaaaata gttatctttg aaactccttt tctaaaggcc
     8701 ctctttttct gatataatgt agaaaaacag ctaaaggaaa gactatgaaa ccactacttg
     8761 aaaccatcga tacccgcttt ggtactgcta gcaagcatgc cttctctcgg ggaaataccc
     8821 tgccatacac aggcgtgcct tttgggatga attactttgt gccccagacc agtgaccagg
     8881 atggatcttg gttttttgat ccgcatctgc ctatctttca ggggattcga ttaactcacc
     8941 agcccagtcc ttggattggg gactactctt ggctccttct gacacctgtc accagtcaac
     9001 tgggtggaga cagcctcttt caccgccagt cttcttatga tatagataaa gcttgcttcc
     9061 agcctcacta tttgaagctc ttttctctgc gttatcagat tgaaacccag ctcacaccga
     9121 cttgctatgg tgcttctatt cgtttgaatc aaaagcaagg caaagccctc tccctctatc
     9181 ttcacgcagc agatgaactg accgtagagc aagtagataa gcggactctt gccctgcgac
     9241 aagaaggtaa aactgaaact aacaaaaatt cgctaacgat gttcactgcc ctgcaaatga
     9301 acacggatat tcttgctatc agccaagaag ggggagactg gcgaattgac ttagcaagta
     9361 gtcaaaccga gatgcaacta gccacttctt tcatctctcc ttctcaagca ctgcttaatc
     9421 tacctcaaga agattttgat agctgtaaag caagtgccca agcggattgg gaaaatctcc
     9481 tccatcgttt tgacattata gagacaggag aggctgaccg aaccttcttt gaccactgtc
     9541 tctacagact cttcctcttc ccacagactt tttatgaggt tgatgagtca gggcaagcca
     9601 tccacatgga tatggctact ggtactgtca agcctggtgt cctctttagc aacaatggtt
     9661 tctgggatac cttccgcacc accttccccc tctttgccct tatcataccg gagcactatc
     9721 aacgcttttt agaaggtttc ctcaatagct accgcgatac tagtttcctt ccaaaatggc
     9781 tggctccaga tgaacggggt atgatgccag gtacactttt agacggtatt atcgcagata
     9841 gcgcctgcaa ggacatggcc cccgacctag aaggagaact cttccaagcc atgctcgaaa
     9901 cagccagcaa agccgaccct ctcggcatca atggccgcca cggactagcc caataccaag
     9961 aactaggtta cctctctacc gaccaccacg aaagtgttag ccatactcta gactatgcct
    10021 atagtgactt ttgtatcgcc aactgtgcca aaaaactaaa aaacatagaa atcgctgaaa
    10081 cctacaaggc tgcttcacaa aattaccgcc agctatttga cgctgagaca ggttacatgc
    10141 gagcacgaga caatcaagga aactttcacc ctgacttctc tccttatagt tgggggcgag
    10201 actacgctga atgctctgcc attcaagcta ctttaggcgt tctccacgac atccctggct
    10261 taatccaact gatgggtgga aaagaaacct ttagcaacta tcttttgaaa gcctgtcaag
    10321 atgctcccct ctttgaaaca acaggctatg gttacgaaat tcacgaaatg agcgagatgg
    10381 ctactgctcc ttttggacaa atagccattt ccaaccagcc tagtttccac attccttatc
    10441 tcttccgcta cagcgattac cctgactaca ctgcccttct tatcaagacg ctccgtcaga
    10501 aagcttttca cccaagttgg gaagcctatc ctggagatga agacaatggc agtctctctg
    10561 cttggtacat ctggtcagct ctcggatttt atccaacctg tccaggaaaa ccaagctatg
    10621 acctcggaat ccctctcttt gaccatctac gagtctacct cgctaaagaa gataaatggc
    10681 tggatatcca tactaaacaa aaccacaacc attttaactt tgtcaaagaa tgccgactgg
    10741 acaaaatact cgtatcaact attcaacacc aagacctctt aaaagctgaa caactaactt
    10801 tcaccctcag ctggctacca aatcactaat aaccaaaaga acctttgcat cgcgcaaagg
    10861 ttcttctttt atgaaacttg gacttgaagt tgatccacaa gctgaccatc caccgttagg
    10921 ttcagataga aatccaaggt tttatctcct gcgaaataca aggttggtag cgtcagactt
    10981 ttttcagtct caccagcttg aaacgcaagg acttgaatct catcctgata ggcgacacca
    11041 tggacacctg tccccggttg aatcgaaatc ttagcttcta aagaggagct actttcacta
    11101 cgttcaatcc taaaatgaag agtctctccc tttgccacag ctaggctttt ttctgcaaat
    11161 gctagttcct gaacaacttc tttttttgat aatccaggag ttttataaag ggaaatcttg
    11221 gtcaatacag ggatagattg tgcctcggta atcatcacgc gcaccttttg tgcctctact
    11281 agcggacctc gcaagaggcg cttatgacca actgtgaagc ccctgccaaa ctcctgccag
    11341 acaccatcca cctctacttg cacatgaaaa gcagcgattc gttgccctag cttcaaatct
    11401 tctcttaact caattacatc aaaagtttta ggagaaccta aatcgagttc taactggatg
    11461 ggcaagtctg catcgtttgc ccaagagctg gtctcaaggc cgtctgtcaa atggcgacaa
    11521 gcaaagtctg cggaaagagc tggaccagat acctcagctc ccagagccaa atcttcttta
    11581 tagagctcat tgcgataggt cgcaaattca taaagtcgtt caatatcctt tgcatcaaag
    11641 agcccagctt gattcggcgg aatattaagc aagagtggag ttcctcgccc tactgagtga
    11701 aagtagattt cgaccaactc ctcgagagac ttaggatcct gatcctcatg gtagaaccag
    11761 cctggacgga tggaaacatc tgcctctccg attgaaaaaa tcgtgcccga gggatccccg
    11821 tgctgaagat agttcagctc tgcttctgtt cctagtttat caggattcac cttttgccac
    11881 agtggatcac ctgcataccc tcgttcattg ccaatccagc ggatactggt gccttctgtt
    11941 gaaaaaatca agcaagcgcc ctgcaggtca cgaatggttt caaaccattt ttcaaattca
    12001 taattaacct tttgcgcgcc ctctcctctg gcaccatcca tccaaacctc agcgaactta
    12061 ccagcattcc catagttagg atttgataag atttccttca actgagccag ataataggca
    12121 ttgtagtccg cttctcggtc cacatgatag aggggactat gggcatccca cggtgacagg
    12181 tagaccccca tatccatatc aaactctgtg gcagcttggg atacttcaag gagcaagtcg
    12241 ccctttcctc tcctccaagg actgacctta accgaataat ctgtgtgagc tgtcggataa
    12301 aggacaaagc catcgtggtg cttgaccacc aaaatcaact ttttgaagcc cgtttccttg
    12361 agcacacgaa cccactcacg cgcatccaac tgactcgggt taaagcgctc aggatcctcc
    12421 tgtccagtcc cccattcttg gtcataaaag gtattaggac cgaagtggat aaaagctgct
    12481 agttcatctc ccagataagc tagctgagtc tgacttggta acggtccatg cggtttgatt
    12541 ttcttcatcg ttatatatct ccttctttag caacttctct tgttcacaag gttatccaca
    12601 ggttgtggat aataaaaaat gatctaaccg ccagctcttt ccaactccaa ctggtaggct
    12661 caggattttt ctcctcaata ttccctcttc aaacagctct gtcatatggt tctgctaaca
    12721 cctctcagaa tgctactctc cataattatt ctcaggcttc tttcaggtca ttgtgtgaag
    12781 accattcact ctccagactt ttccacagat tgtgaataag tgattattct aaactatcac
    12841 ctcgtcgact ataacaaaaa ataaaaagag ggtcaataag ataattatct cttcctaaat
    12901 actcagaaaa gattctataa tttgtacaat tgagcaagaa atgcttctcc aaaatctatc
    12961 ttcaaaagaa tgttgcatct ttttatcctt tcacacaaac atttctcttt atacagatcc
    13021 aagtgataac cagatgataa ttggacactt tttggtcatt tgtatatttt ttgaaaaatt
    13081 ttttaaaaaa attttatatc ctttttatag aagtttatgc atttgtatct atgtattcta
    13141 tcctatgtta tgtataataa cataaaattg tgctaaacat cataatttat attattttcc
    13201 gagaaattat agccattgac attacctagg aattgcgtta taacatacat gtaagcggta
    13261 cccaaaatgg tgccaagtca aaatttttaa ggaggaaaat acatgtcttc tcatccaatt
    13321 caggtcttct cagaaattgg gaaactgaaa aaagttatgt tgcaccgtcc aggcaaggag
    13381 ttagaaaact tgttgccgga ctatcttgaa aggcttcttt ttgatgatat tcctttcttg
    13441 gaagatgctc aaaaagaaca tgatgcattt gcccaagctc ttcgcgatga aggaattgag
    13501 gttctctacc tagaacaact cgctgctgaa tcattgacct ctccagaaat ccgcgatcaa
    13561 tttatcgagg aatacttaga cgaagccaac atccgtgatc gtcaaaccaa ggttgctatt
    13621 cgtgaattgc ttcacggcat caaggacaac caagaattgg ttgaaaaaac aatggctggg
    13681 attcaaaaag ttgaattgcc agaaattcct gacgaagcta aagatctaac tgacttagtt
    13741 gaatcagatt atccatttgc aattgacccg atgccaaacc tctatttcac tcgcgaccca
    13801 tttgcaacaa ttggaaacgc cgtatcgctt aaccacatgt ttgcagacac tcgtaaccgt
    13861 gaaacactct acggtaagta tatcttcaaa taccacccag tctatggcgg aaaagtggat
    13921 ttggtctaca accgtgaaga agatacgcgt atcgaaggtg gagacgagct agttctttct
    13981 aaagacgtcc ttgcagtagg tatctctcaa cgtacagacg cagcttctat cgaaaaactt
    14041 ttggtcaaca tcttcaagaa aaatgttggc ttcaagaaag ttttggcctt tgaatttgct
    14101 aacaaccgta aattcatgca cttggatact gtcttcacta tggtagacta tgacaagttc
    14161 actattcacc cagaaatcga aggcgacctt cacgtttact cagttactta cgaaaacgaa
    14221 aaacttaaaa tcgttgaaga gaaaggtgac ttagctgaac ttcttgctca aaaccttggt
    14281 gtagaaaaag ttcatttgat tcgttgcggt ggtggcaata tcgtagcagc tgcgcgtgaa
    14341 caatggaacg acggttctaa cactttgacc atcgcacctg gtgtggtagt tgtttatgac
    14401 cgcaataccg tgaccaataa gattttggaa gaatacgggc ttcgcttgat taagattcgc
    14461 ggaagtgaat tggttcgggg ccgtggtgga cctcgttgta tgtctatgcc atttgaacgt
    14521 gaagaagtgt aatcgctgtt cggtattcgt caatagaaaa tgtaaaaaat agaaagagga
    14581 aataataaaa tgacaaattc agtattccaa ggacgcagct tcttagcaga aaaagacttt
    14641 acccgtgcag agttagaata ccttattggt ctttcagctc acttgaaaga tttgaaaaaa
    14701 cgcaatattc aacaccacta ccttgctggc aagaatatcg ctctcctatt tgaaaaaaca
    14761 tctactcgta ctcgtgcagc ctttacaact gcggctatcg accttggtgc tcacccagaa
    14821 tacctcggag caaatgatat tcagttgggt aaaaaagaat ctactgaaga tactgctaaa
    14881 gtattgggac gtatgtttga cgggattgaa ttccgcggat tcagccaacg tatggttgaa
    14941 gaattggcag aattctcagg cgttccagta tggaacggtc taactgacga atggcaccca
    15001 actcaaatgc tcgctgacta cttgactgtt caagaaaact tcggtcgctt ggaaggcttg
    15061 acattggtat actgtggtga tggacgtaac aacgttgcca acagcttgct cgtaacaggt
    15121 gctatccttg gtgtcaatgt tcacatcttc tcaccaaaag aactcttccc agaaaaagaa
    15181 atcgttgaat tggcagaagg atttgctaaa gaaagtggcg cacatgttct catcactgaa
    15241 gatgctgatg aagcagttaa agatgcagac gttctttaca cagacgtttg ggtatcaatg
    15301 ggtgaagaag acaaattcgc agaacgtgta gctcttctta aaccttacca agtcaatatg
    15361 gacttagtta aaaaagcagg caatgaaaac ttgatcttcc tacactgctt gccagcattc
    15421 cacgatactc acactgttta tggtaaagac gttgctgaaa aatttggtgt agaagaaatg
    15481 gaagtaacag acgaagtctt ccgcagcaag tacgctcgcc acttcgatca agcagaaaac
    15541 cgtatgcaca ctatcaaagc tgttatggct gctacacttg gtaaccttta tattcctaaa
    15601 gtataatttt agataataaa ccgtctacca acagctatga gggctgcgac taatagcttt
    15661 agtccggtcc tcttttatgt aatggtaatc tattatttct tataaaatat gtgaaaaatc
    15721 attaaattga aatctaaacg cattctattg agtgtgataa aggagaattt atggcaaatc
    15781 gtaaaattgt agtagctttg ggaggaaatg cgattctttc ttctgaccca tcagcaaagg
    15841 ctcaacaaga agctttagtt gaaacagcta agcatcttgt aaaattgatt aaaaatggag
    15901 atgatttgat tatcactcac ggtaatggac ctcaagttgg gaatctcttg ctccaacatt
    15961 tggcatcaga ctctgaaaag aaccctgcct tcccactcga ctcacttgtc gctatgacag
    16021 aaggtagcat cggtttctgg ttgaaaaatg ctttgcaaaa tgctctcttg gatgaaggca
    16081 tcgaaaaaaa tgttgcctct gttgtaacgc aagttatcgt agataaaaat gatccagctt
    16141 ttgttaactt gagtaaacca atcggtcctt tctattcaga agaagaagca aaagcagaag
    16201 ccgaaaagag cggagcgact ttcaaggaag atgctggccg tggctggcgt aaggtcgttg
    16261 cctcaccaaa acctgttgac atcaaagaaa ttgaaaccat ccgtactctt ttaaataatg
    16321 gtcaagtcgt cgtagctgca ggtggtggcg gtattcccgt cgtcaaagaa aacaatggac
    16381 atttgactgg tgtcgaagcg gttattgata aagacttcgc ttcccaacgt ttggcagaat
    16441 tggttgatgc agacctcttc atcgttttga caggtgtaga ttatgtattt gttaactaca
    16501 acaagccaaa ccaggaaaaa ttggaacatg tgaatgttgc ccagctggaa gaatatatca
    16561 aacaagatca gtttgcacca ggtagcatgc ttccaaaagt agaagcagct atcgcttttg
    16621 tcaatggtcg tccagaagga aaagcagtta ttacttccct tgaaaatcta ggcgccttga
    16681 ttgaatctga aagcggaaca attattgaaa aaggataagt tgttttacta ataagatgta
    16741 ttctatttct agtatcttta tatcaaatta gaaattattc ttgaaaacat gtacaatatt
    16801 tcaaaagata ctagttttag actttaatat ggtaaaacaa atataaatag aaagcgtttt
    16861 cttgaatgtt tatttaagaa agtagttggt tttttacact ttgttagaca tcaggaggaa
    16921 aaacaaatga gtgaaaaagc taaaaaaggg tttaagatgc cttcatctta caccgtatta
    16981 ttgataatca ttgctattat ggccgtgcta acttggttta tccctgcggg ggcctttata
    17041 gaaggtattt acgaggctca gcctcaaaat ccacaaggga tttgggatgt cctcatggca
    17101 ccgattcggg ctatgctagg tactcatcca gaggaaggtt cgctcattaa agaaacgagc
    17161 gcagcgattg atgtagcctt cttcatcctt atggttggtg gtttccttgg cattgtcaac
    17221 aaaactggtg ctcttgacgt agggattgcc tctatcgtga agaagtataa gggccgcgaa
    17281 aaaatgttaa ttttggtatt gatgcctttg tttgccctcg gtggtacaac ttatggtatg
    17341 ggtgaagaaa caatggcctt ctatccactc cttgtgccag ttatgatggc cgttggtttt
    17401 gatagcctga ctggtgttgc aattattttg ctcggttctc aaatcggctg tttggcatct
    17461 actctgaatc catttgcgac aggtattgct tcagcgactg cgggagttgg tacaggggac
    17521 ggtatcgtac ttcgtctgat cttctgggtt accttgactg ctcttagtac ttggtttgtt
    17581 taccgttatg cggataagat tcaaaaagat ccgactaagt cactggttta tagtactcgc
    17641 aaagaagatt tgaaacactt taacgtagaa gaatcttcat ctgtagaatc tacacttagc
    17701 agcaaacaaa aatcagttct cttcttattt gtgttgacat tcatcttgat ggtattgagc
    17761 ttcattccat ggacagacct tggcgttacc atttttgatg actttaatac ttggttgact
    17821 ggtcttccag ttattggtaa tattgtcggt tcatctactt ctgcactagg tacttggtac
    17881 ttcccagaag gcgcaatgct ctttgccttt atgggtatcc tgattggtgt tatttatggt
    17941 cttaaagaag ataagattat ctcttccttc atgaatggtg ctgctgactt gctcagtgtt
    18001 gccttgatcg tagcgattgc tcgtggtatt caagttatca tgaacgacgg tatgattacc
    18061 gatacaatcc tcaactgggg taaagaaggc ttgagcggtc tatcttcaca agtctttatc
    18121 gttgtaactt atatcttcta tctacctatg tcattcttga tcccatcttc atctggtctt
    18181 gccagcgcaa ctatgggtat catggctcca cttggagaat ttgtaaatgt ccgtcctagc
    18241 ttgattatca ctgcttacca atctgcttca ggtgtcttga acttgattgc accaacatct
    18301 ggtattgtga tgggagctct tgcacttgga cgtatcaaca ttggtacttg gtggaaattc
    18361 atgggcaaac tcgtagtcgc tattattgta gtgaccatcg cccttcttct ccttggaacc
    18421 ttccttccat tcctataaaa tagtgagtga ggtgattcca tgaaaataga tataacaaat
    18481 caagttaaag atgaatttct tatatcatta aaaaccttga tttcctatcc ttcagtactc
    18541 aatgaaggag aaaatggaac accttttgga caagcaatcc aagatgtcct agaaaaaact
    18601 ttagagattt gtcgagacat aggtttcact acctatcttg accctaaagg ttattacgga
    18661 tatgcagaaa tcggtcaggg agcagagctt ctggccattc tctgtcattt ggatgttgtt
    18721 ccatcaggtg atgaagcaga ttggcagaca ccgccatttg aagcaactat caaagacggc
    18781 tgggtattcg gacgtggtgt ccaagatgat aaaggccctt cgctcgcagc tctctatgca
    18841 gtaaaaagct tgctggacca aggtattcag ttcaaaaagc gcgtacgctt tatctttggt
    18901 accgatgagg aaaccctctg gcgctgcatg gcacgctaca ataccatcga agaacaggcc
    18961 agtatgggct ttgcacctga ctcatctttt cctctgacct atgctgaaaa agggcttcta
    19021 caggtcaaac ttcatggccc tggatcggat caactagagc ttgaagtagg aggcgccttt
    19081 aacgttgtac cagacaaggc caactaccaa ggtcccctct atgaacaggt ttgtaacggt
    19141 ctcaaagaag ctggttatga ttaccaatcc actgaacaaa ccgtaacggt tctcggagtg
    19201 ccaaagcatg ctaaggatgc tagtcaaggt atcaatgctg tcatccgact agctaccatt
    19261 cttgctcctc tccaagaaca ccctgctctc agttttcttg caacacaagc aggtcaagac
    19321 ggcacaggaa gacaaatctt tggtgatata gcagatgaac cttctggtca cctatccttt
    19381 aatgtcgcag gtctcatgat caatcatgaa cgttctgaaa tccgtattga cattcggact
    19441 cctgtcttag ctgacaagga agaactagta gagttgctta caagatgtgc acaaaactac
    19501 caactccgct acgaagagtt tgactatcta gcgcctctat acgtcgcaga agacagtaaa
    19561 ctcgttagca cactgatgca aatctaccaa gaaaagactg gcgataacag tcctgctatt
    19621 tcatccggtg gtgccacttt tgctcgcacc atgccaaatt gtgtagcctt cggcgcctta
    19681 ttcccaggag cgaagcagac agaacatcag gcaaatgaat gtgccgttct agaagatttg
    19741 taccgtgcta tggatattta tgccgaagcc gtctatcgac ttgcaactta atcaggcaac
    19801 tgtttctacc aaaaaaaatc gaccgattaa tgaactgcac cccaaaagtt agacagaata
    19861 aatctaactt ttggggtgtt ttattatgaa attgagttat gaagataaag ttcagatcta
    19921 tgaactaaga aagcaaggac aaagcttcaa acagctttca aaaagatttg gtgtggatgt
    19981 ttctggtcta
//
LOCUS       DAVKZI010000037        18763 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKZI010000037 DAVKZI010000000
VERSION     DAVKZI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.038"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(318..1124)
                     /gene="yidA"
                     /locus_tag="VXB18_001617"
     CDS             complement(318..1124)
                     /gene="yidA"
                     /locus_tag="VXB18_001617"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0382794.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1137..2441)
                     /locus_tag="VXB18_001618"
     CDS             complement(1137..2441)
                     /locus_tag="VXB18_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0382795.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2513..2890
                     /locus_tag="VXB18_001619"
     CDS             2513..2890
                     /locus_tag="VXB18_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0382796.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKRDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYILTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2981..3313
                     /locus_tag="VXB18_001620"
     CDS             2981..3313
                     /locus_tag="VXB18_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0382797.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3325..4896
                     /gene="ffh"
                     /locus_tag="VXB18_001621"
     CDS             3325..4896
                     /gene="ffh"
                     /locus_tag="VXB18_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0382798.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5091..6374)
                     /locus_tag="VXB18_001622"
     CDS             complement(5091..6374)
                     /locus_tag="VXB18_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0382799.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSIALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6677..7390)
                     /gene="rsmG"
                     /locus_tag="VXB18_001623"
     CDS             complement(6677..7390)
                     /gene="rsmG"
                     /locus_tag="VXB18_001623"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0382800.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7484..8044
                     /locus_tag="VXB18_001624"
     CDS             7484..8044
                     /locus_tag="VXB18_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0382801.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            8046..8945
                     /gene="htpX"
                     /locus_tag="VXB18_001625"
     CDS             8046..8945
                     /gene="htpX"
                     /locus_tag="VXB18_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0382802.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(8989..10548)
                     /locus_tag="VXB18_001626"
     CDS             complement(8989..10548)
                     /locus_tag="VXB18_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0382803.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRLLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10787..11104)
                     /locus_tag="VXB18_001627"
     CDS             complement(10787..11104)
                     /locus_tag="VXB18_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0382804.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYDHVKHVLSLYGPV
                     FEF"
     gene            11274..11816
                     /locus_tag="VXB18_001628"
     CDS             11274..11816
                     /locus_tag="VXB18_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0382805.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11816..12445
                     /gene="nth"
                     /locus_tag="VXB18_001629"
     CDS             11816..12445
                     /gene="nth"
                     /locus_tag="VXB18_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0382806.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12656..13177
                     /gene="pyrR"
                     /locus_tag="VXB18_001630"
     CDS             12656..13177
                     /gene="pyrR"
                     /locus_tag="VXB18_001630"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0382807.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13196..14119
                     /locus_tag="VXB18_001631"
     CDS             13196..14119
                     /locus_tag="VXB18_001631"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0382808.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14169..15248
                     /gene="carA"
                     /locus_tag="VXB18_001632"
     CDS             14169..15248
                     /gene="carA"
                     /locus_tag="VXB18_001632"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0382809.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15561..18737
                     /gene="carB"
                     /locus_tag="VXB18_001633"
     CDS             15561..18737
                     /gene="carB"
                     /locus_tag="VXB18_001633"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0382810.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5456 a         3612 c         4212 g         5483 t
ORIGIN      
        1 actactgtaa gatatgataa agtcttattt ttagtgaagt atcctaattt gtataattga
       61 ttgtgtgtag attcagggtc aatttgaaga gagtatttaa aatatcttgg gaaattataa
      121 tttctccctg ttttttgagt ccaatctatg agtatgagtt gcccaggagt aaggccacat
      181 tctaattcgt ttaggtaaaa attgttacaa tcagaatttg tgtctctatt atgattattt
      241 tgttttaaat taaatagttt gctaaaaaaa ttcattggat tttattgcta atcaattctt
      301 attgaaaaat gatactttta cagtacccat gttcggatgg cgtgggcaac gccggattcg
      361 tcatttgttt tcgtgatgta tttggcgatt tttttgattt ctggatttcc gttttccatg
      421 actacagggt tgccaacgac ttccagcatg gcacggtcat tttcttcgtc tccgatagcc
      481 atggtttcat ctttggttaa tcctagtttt tcagccaagt gagtaatagc tgaacccttg
      541 tctacattct ttttaaggag ttcgaggtag aaaggagcag atttgttgat ggagtagcgt
      601 tcgtaaaatt ctgctggtat cttttcaatc gcagcatcga gaatctctgg ttcatcaata
      661 aacatacatt tgacgatttc cttgccagcc atttcttcag gagtgcggta gaagataggc
      721 atgctgacga gggttgattc gtgtacagtg tatgttccga tattgcgatt tgcagtatag
      781 ataccgtcct tagtaatagc atgcatgtga acaccaagct tgcgactgag aaattccata
      841 tccagataat cctcataggt caaggattcg ctgataatct catggccagt agcagtttct
      901 tggacaaggg caccgttgaa ggtcaccaca tagtcacctt ggtctctcaa ctgcaagtcg
      961 tccagaagtt tggcaacacc tgcgatgggg cggccagttg caatcacgac tttgacacca
     1021 gcttctttgg catcttggat ggcagaaaag acttcaggag tgatttcctt ttggctgttg
     1081 actagggttc cgtcaatatc gacggcgatt agtttaatac tcataaattt cctcttttag
     1141 tttttatttg gggtaaaatg atcgttctca atcaagtgta aaaattgctg ggtgatgctt
     1201 gcgaagatgc tgttttggtc taacatttct ttcgggaaat aaaagcgatt atctccgtgg
     1261 cgacttccag caagggattg gacgataggg gacaggctag agagttctgc cagttctcca
     1321 tttttttgta aaatctcaat ctgtgtcctt ggattttcag attcgggacg gtaaatatca
     1381 taagggaggt caaagttctt atgaatggca gtatagtagt cgggatcaaa gccgatgtcc
     1441 tcaaccaatt ttctcatgct agcgagttgg tcttggtctt cttgtgaaaa ggtaatggat
     1501 ttaaagacct tgcggttgac aaagcgttgt gacaagtctg cgagaatctt gtcaggactg
     1561 gtcatccaga gttgaaagta ggtattcatc acaccatcat ctagagccag atagtcagtc
     1621 aaggtcacat ttttttcaaa gaaaggcagg aggtgtggag aagttcgtgc aaagaagtcc
     1681 ttgtcttcag gatagagttc cttggcgcgt ttgaggagat tctgcaggag aacttccatg
     1741 gcgcgtgttg cggggtggaa ataaacctgc atgtacatct ggtagcgact gaggacgtag
     1801 tcttcgatgg cgtgcatgcc attgcgctga aaggcgatac cattttcgat aggacgaatg
     1861 actcggagga tgcgagtcag gtcaaattcc ccataggatg ctcctgtaaa ataggagtcg
     1921 cgcaagagat agtccatgcg atctgcgtca atctgactag aaatgagctg cacgacctgc
     1981 ttattaggat aggtatggtc aatgacactg gccacctttt ctgggaaatc gggcgctact
     2041 tgtagcaaga cttggtgaat ctctgtctca ggattttgaa taatctcctg agtaatggct
     2101 tcatggtctg tatcaaagag atgttcaaaa gtatgggagt aggcgccatg cccaaggtca
     2161 tgtaggagag cagcggtcat ggtcaagaga gactcggcag gattccattc ctcaggatat
     2221 ttttcttcaa aaatttctgt gatacgtcgt gcaatctcat agactcccag acagtgagag
     2281 aagcgactat gctctccacc gtggaaggta taactggaag tccctagttg cttgatccgg
     2341 cgcaaacgtt gaaattcttt tgtattaatc aagtcataga tgatttgatt attgacatgg
     2401 atgtagttgt gaactgggtc acggaatact ttttcgttca tatgaccatt atagcaaaat
     2461 cctgctcttt ttggtaaaat agtaggacaa gagacaagaa agaggacctg atgtgaagat
     2521 tcggatgcga aatacaattc agtttgatga gcagttggaa gtgattgacc agctttatga
     2581 tgtggaagtg catgaaaaaa gagattatag ctacctgctt ttctataatg aggaaaagga
     2641 aaaagtagtg attaaatttc atggtcaaga acttgtgatg agccgatttt ctaatcccaa
     2701 gaccattatg cgctttctaa aggatagcga tagtttagcc tatattctta cacctatggg
     2761 catgcaggag tttaccatcc aaacgagcca ttatcaagtt gataggcaaa agattgaact
     2821 agattatcaa ctacaaaatc aagagggaca tccctttgcc agctatcaat tggaaattac
     2881 ttggggctag gctcatgtct ttttcaaatt tagctatcta tcttcttgga tcggcttcct
     2941 agtgtggtag attaggctaa tttttggtat aataaaagtt atggaaatcg aaaaaaccaa
     3001 tcgtatgaat gcgctctttg aattttatgc ggcgcttttg acagataagc aaatgaatta
     3061 tatcgagctc tactacgctg atgattacag ccttgctgaa attgccgagg agttcggtgt
     3121 cagtcgtcag gctgtctatg acaatatcaa gcgaacagaa aagattctgg aagattatga
     3181 gatgaaattg catatgtact cggactatat tgtccgcagt cagatttttg atcagatttt
     3241 ggagcgctat cccaaggata actttctgca ggagcagata gaaattttaa caagcattga
     3301 taatagagaa taagaggaag aaaaatggca tttgaaagtt taacagaacg tttgcagaac
     3361 gtctttaaaa atctacgtaa aaaaggaaaa atctctgaat ctgatgtcca agaggcaacc
     3421 aaagaaattc gcttggcctt gctcgaggcc gacgttgcct tgcctgttgt aaaggacttt
     3481 atcaagaaag ttcgtgagcg tgcagtcggg catgaggtca ttgatacact taatcctgcg
     3541 caacagatta ttaaaatcgt tgatgaggaa ctgacagccg ttttaggttc tgatacggca
     3601 gaaattatca agtcacctaa gattccaacc atcatcatga tggttggttt acaaggggct
     3661 ggtaaaacaa cctttgctgg taaattggcc aacaaactca agaaagaaga aaatgctcgt
     3721 cctttgatga ttgcggcgga tatttatcgt cctgctgcca ttgatcagct gaagacactg
     3781 ggacaacaga ttgatgtgcc ggttttcgct cttgggacag aggttccagc tgttgagatt
     3841 gtacgtcaag gtttggagca agctcaaact aatcataacg actatgtctt gattgatact
     3901 gcgggtcgtt tgcagattga tgagctcctc atgaatgagc ttcgtgatgt gaaagcattg
     3961 gctcaaccaa atgaaatctt gcttgtcgtt gatgctatga ttggtcagga agcagccaat
     4021 gttgcgcgtg agtttaatgc tcagttggaa gtgactgggg tcatccttac caagattgat
     4081 ggcgatactc gtggtggtgc tgctctgtct gttcgtcaca ttactggaaa accaatcaag
     4141 ttcactggta caggtgaaaa gattacggac attgaaacct tccacccaga ccgcatgtct
     4201 agccgtatcc ttggcatggg ggatatgctc actttgattg agaaagcttc tcaggaatac
     4261 gatgaacaaa aagcccttga aatggctgag aagatgcgcg aaaacacctt tgattttaat
     4321 gatttcatcg atcaattaga tcaggtgcaa aatatggggc cgatggaaga cttgctcaag
     4381 atgattccag gtatggccaa caatccagcc cttcaaaaca tgaaggtgga tgaacgccag
     4441 attgctcgta aacgtgccat tgtgtcttcg atgacacctg aagagcgtga aaacccagat
     4501 ttgttaaatc caagccgtcg ccgtcgtatt gctgctggtt ctggaaatac attcgtcgaa
     4561 gtcaataaat tcatcaagga ctttaaccag gctaaacagc tcatgcaggg tgttatgtct
     4621 ggggatatga ataaaatgat gaagcaaatg gggattaatc caaataacct tcctaaaaat
     4681 atgccaaata tgggaggaat ggatatgtct gcccttgaag gaatgatggg acaaggcggt
     4741 atgcctgact tatcagctct cggaggagca ggaatgccag atatgagcca gatgtttggt
     4801 ggcggtttga aaggtaaaat tggtgaattt gccatgaaac agtccatgaa acgtatggct
     4861 aacaaaatga agaaagcgaa gaagaaacgc aagtaagaca agagattgat gcaaatctca
     4921 tttgatgaga aaataaagaa aaaatttcta tgataaaacg tacagtatca aggttttaga
     4981 atatctgata ttatacgttt tttgatttta ataattttgt taagacactt ttattatggt
     5041 atgcgaaaaa tccactcagc tgtctgagtg gattaggtgt atttagactc ttagtcttta
     5101 ttttcgtatg gcaagatcaa gttcaagatg attcctgtca tggctgaaag ggcagtacct
     5161 gaaagtgtaa ctggaccaag tttaaggata gctcctccaa gtccaagaac caacatagca
     5221 cttgcgatga tgaggtttcg catttgagcg aaatcaacac gttctttaat caagactttc
     5281 aaaccattgc tggcgataac cccatagaga aggattgaca taccaccaag tacagcgttt
     5341 ggaatagttg aaatcaaggc agtgaattta ccaaggaagc tgagggcaat cgcgatgaag
     5401 gcagcgttac ggataactga gacagaagcg atacgagtca taccgataac ccctgtattt
     5461 tctccgtaag ttgtattggc tggtccacca aggaaggcag aaacagaagt tgcgataccg
     5521 tcaccaagaa gagtacggtg aagacctggt tcttttaaga attgacgacc acagatttga
     5581 cccaaaacag tatggtctcc gatatgttca gaaattgtta cgatagcgat tggcaagata
     5641 gcgatggctt ctggaccaaa gtaaagattg tactctttaa aggcaccacc tgtgctaaat
     5701 ggcaagtaga aaccaggaat ttcgaaccag ttggctttaa gaactggtgt aaagtcaacc
     5761 aagccaagag ttagtgcgaa aaggtaacca ccgataatgg caaagaggaa tggaatgatt
     5821 cgtaggaagc cttttccttt tgtattgata aaggcagcaa ttaggaaagt aacaacggct
     5881 accagagcat ttttccaatt tccgtctgct acaagacctg cattggtaac agctgaacct
     5941 gcaagtccaa gaccgataac gatgatcata ggaccgataa tgattggtgg caagagttta
     6001 tcaatccatt ttgttcctac aaatcggatg ctggtagcaa caaggacata gaccaaacca
     6061 gtcaagataa cccctgtttg ggcagcagat acatcccccc ccatttcttt catagccagt
     6121 gacatagctg tgataaaggc aaatgaagaa cctagataaa ctggaacttt aaaaccagta
     6181 gcaatcatgt agatgagtgt tccaacacct gaagcaaaaa gggcaataga tacaggcatt
     6241 cccaaaatca atggtaccaa gatggtcgca ccaaacatgg cgaaaacgtg ttggaaacta
     6301 aggagaattc cttttccatc cgaaggacgt tggtcaacgt ctagtaacaa atcaacagtt
     6361 gattcttgtt tcatataaac ctcacttttg ggcatcagaa aagagcccat tattttacag
     6421 caataggccc tcagagtaag acttctctaa aatctagact ttaaagagtt tcaaatattt
     6481 ctgcgtcttc gtcacctcac gggatgacat taaaaacctt tgcttaggat agtatagcag
     6541 aaaaaaatga ttttgtaaat cattttttcc cgagcctaga aataaaagag cgaggctgat
     6601 tttgtaaatc attttttccc gagcctaaaa ataagagagc gaggttgatt ttgtaaatat
     6661 ttttttactt aaaaatttaa agcgggcgtt tatttggcat accagcctta cgtggatatt
     6721 tatttggtgt ttcttttttc ttttctacca ctgtgatgta acgcggatct ctatttggta
     6781 gggcgtagct gagattgtct tcgactttac taaaaaggag attgagggca ttcttagctt
     6841 ctaacaactc ctcaggcgca ttgctggcct tgagtgccaa tagttttcca ccaaccttaa
     6901 ggtagggaat agtcaattca gataggacct gcatacgggc aaccgcacga gctgttacaa
     6961 aatcatattg agcacggaag ttcttgtctt gggcaaaatc ttcggcacgt ccgtggtaga
     7021 aatgaactcc gttcaaatcc agttcttgag ccaagagttg taggaagttg atgcgcttat
     7081 tgagtgaatc aataatggtc acatctaact ccggatagag aattttcatt ggtagactag
     7141 gaaatcctgc cccagccccg atatcaagaa gtttgatagt ttcattggga atcaaacctt
     7201 gaagaatggg tgcaatcgaa tcgtaaaaat gtttgagata aacttcttcc ttgtccgtaa
     7261 tcgccgtcaa attaatcttc tcattccact cgaccaagag ctcaaaataa cgttcaaatt
     7321 gttctttttg ctggtccgaa agtggaagat tctgctcggc aagcaagttg taaaatgttt
     7381 ttggtttcat agttatttcc ttctttagta tcatcttatt ttaccacaat catagaaaat
     7441 ttgatatact ggtactaatc taaaagcaga aaggacttat attatgactt ggattattct
     7501 tggagtttta gctcttgttg ttatttttgt gattgttagc tataacggtt tggttaaaaa
     7561 tcgtatgcaa accaaggagg cttggagtca gattgatgtt cagttgaaac gtcgcaatga
     7621 tctcttgcca aacttgattg agactgtaaa aggttatgcc aaatatgaag gttctaccct
     7681 tgaaaaggtg gcagaactac gtaaccaagt ggcggcagcg acttcaccag cagaagctat
     7741 gaaagccagt gatgccctca ctcgtcaggt ttcaggtatt tttgcagttg cagaaagcta
     7801 tccagatttg aaagctagtg ctaactttgt taaattgcaa gaggagttga caaacacaga
     7861 aaataaaatt tcttactctc gtcaactcta taacagtgtt gtcagcaact acaatgtaaa
     7921 attagaaact ttcccgagca atattatcgc tggaatgttt ggatttaaag cggcagattt
     7981 ccttcaaaca cctgaagagg aaaagtcggt tcctaaagtt gattttagcg gtttaggtga
     8041 ctaagatgtt gtttgatcaa attgcaagca ataaacgaaa aacctggatt ttgttgctgg
     8101 tatttttcct actcttagct cttgttggtt atgcggttgg ttatctcttt ataagatctg
     8161 gacttggtgg tttggttatc gcactgatta tcggctttat ctacgctttg tctatgattt
     8221 ttcaatcgac agagattgtc atgtccatga atggagcgcg tgaggtggat gagcaaacgg
     8281 caccagacct ctaccatgta gtggaagata tggctctggt cgctcagatt cctatgcccc
     8341 gtattttcat tattgatgat ccagccttaa atgcctttgc gacaggttct aatcctcaaa
     8401 atgcggctgt tgctgcgact tcaggtctac tagctatcat gaatcgtgaa gaactagaag
     8461 ctgttatggg acatgaagtc agtcatattc gtaattatga tatccgtatt tcgactattg
     8521 cagttgccct tgctagtgct atcaccatgc tttctagtat ggcaggtcgt atgatgtggt
     8581 ggggtggagc aggtcgcaga cgaagtgatg atgaccgaga tggaaatggt cttgaaatca
     8641 ttatgctagt ggtttcccta ctagctattg tactggcacc tctcgctgca accttggttc
     8701 agctcgctat ttctcgtcag agggaatttc tggcagatgc atctagtgtc gagctgactc
     8761 gcaatcccca gggaatgatt aatgccctag ataagttgga caatagcaaa cctatgagtc
     8821 gccacgtcga tgatgctagc agtgcccttt atatcaatga tcctaagaaa ggtggggggt
     8881 tccaaaaact cttttatacc cacccaccta tctcagaacg gattgaacgt ttaaaacaga
     8941 tgtaaaagaa tccagaggtc gtctctggat ttttgctatg ttgcaaattt ataaatcttc
     9001 taaattaact agcttcaaac cgtgttctgt catgcgatag atgatcgagc agacttcttt
     9061 taataaacga cggtcatgcg aaacagtgat gagaccgcct ggataggtag caaagagttt
     9121 tctgatttgg ggttgagaag tgggagaaaa gtttcgtgtg ggttcatcca gcaggagaaa
     9181 gtttggtttg cgcaggacta aatccaaaag caggagtttt ccctgttgtc cgccagataa
     9241 ggagcgaatt tgatgctgca tttctggata actgaaattg agactagcta ggtgagattg
     9301 gattttctgt agttcctctt tttccccagt tttactgaga taggctattg gggataaatc
     9361 caattgcagt tttttgtggt aatcttgtgg cataaaacca agtgaaatct ctcttttatc
     9421 attcagaagt ctctgtaact tggctaacag agttgatttc ccaacaccat ttggcccgat
     9481 aataccgatt ttttcttggc cacggacagt tagttgtagt ttttgaacca aaactcggtc
     9541 gtcaatggac aaattttctt tttccagttg gactaagact ttagaagctg gtaatggttg
     9601 gatgtctgaa aagaaaagtt ggatttgttc ctcttcaagt ggcttttgag tcatggactg
     9661 agctgccttt tcgtagcgtt tttcttgtga gaggacagtt ttcatctttt tagccaatag
     9721 gcgaccggca gtactatctt tggtagctcg aagcgcagtt tctacatttt gcttaactct
     9781 ccgatgtttt tccatggttt tatcgtaggc tctttggttg ttagcagctt gctgactttg
     9841 tttggcaaaa ttagcctttc tctgctcact atagctatca tagtctaaat gctctactag
     9901 cgtttccgct tctttacggt gtttgaccag tcgcaagtga acaatagtgt ctgccgtttc
     9961 agaaagaaag tcttcatcat gggaaatgaa aataacggtt tgcctggtct tttgaatctg
    10021 gccttttagc caatcaactg tctcaaggtc taggtcattt gaaggttcat ctaaaaatag
    10081 aatctcaaag ggtttggcta actcatggat aagctgaatt ttcaaagctt cgccccctga
    10141 tagattgcca atctcttggt cacttgcgaa acgattgcta tcaaaatgca attcctccgc
    10201 caaacgatag aggatactgt agtctaaatc aatagaatct aaaaagaagt agtcgtgtaa
    10261 agttttcttt tttaggtcct cagggacttt ttgaggaatg taggccagtg actgatagtc
    10321 agattggatg tttcccttga tagtgaaatc agacaaagct tcccccatta aaattttaag
    10381 taaggttgat ttgccatttc cttcttcacc aataatagca accttttccc cgtcttggat
    10441 ggtcatggtt aggtcagata caagatctcg taaatctttg ttttgtgtga tggttagatg
    10501 attgattttt atcatatgat ttccctttct agaatgttca tagtgcataa caaaaagctc
    10561 tactttacct agtagagccc aaagtctatg tcaaaaaaac tctattaaca tgccagaaaa
    10621 agagcataaa agagcacaca aaaagagaca aaaacaagat ctactaaata aaggttcttt
    10681 atttgataga cttagttgtt catgtctccc ttacctccga gtattagtat ctttatatta
    10741 tacctttaag gaaattttgt caacagaaaa ctggaaattc tatgctctaa aattcaaaaa
    10801 caggtccata gagacttagt acgtgtttga catgatcgta atggaattta tcatagtttc
    10861 gccaagcagt gcgtgcttga tcgtttagtt ttaggctacc cagtccaatc agaagactgg
    10921 taggttggta aaatttctca agatcaatta agatactgtt gttcaactgt tccgtttttt
    10981 tgagctcttg catagtagtg tttagcagct cttgtagtcg aatatcatct gccgtaccct
    11041 gtttacagtt ttggtagctt ttatttaact tggataggag ttgaatgagt ttcttgtctt
    11101 ccatgtgagc atcctccttg atctgatgta ctctttccct atagtatagc actaaaaaat
    11161 aaaactatca tagtaaatat gttaaaattt tgaattttaa ttacaaagtt tggtgtgctg
    11221 atttgtagcc ttttcatggt ataatcaaga gagtaaatct ttatggagga agtatgaaat
    11281 taaatattca agaaattcgt aagcagtctg aaggtttgaa ctttgaacaa acgttagatt
    11341 tagttgatga cctgcgtgca cgtaatcaag aaattttaga tgtaaaagat atccttgcag
    11401 ttgggaaagt acaatatgaa gaccgtatgt atttcttaga ttatcaacta tcttatacca
    11461 ttgttcttgc ttcgagtcgc agtatggagc cagttgagtt agttgaatct tatccagtca
    11521 cggaagtttt catggaaggc gcaactaacc agctagatca agaagtttta gatgatgact
    11581 tggtcttgcc catcgaaaat ggggagcttg accttgctga gagtgtatca gacaatatcc
    11641 tgctaaacat tcctatcaag gtcttgacgg ctgaagaaga agctggtcaa ggatttatct
    11701 caggaaatga ctggcaaatc atgacagagg aagaatacca agctcaaaaa gcagtaaaga
    11761 aagaagaaaa cagtcctttt gctggcttac aaggactatt tgacggagat gaataatggt
    11821 cttgtcaaaa aaacgagcac gaaaggtgct agaagaaatc attgccctct tcccagatgc
    11881 caagcctagt cttgatttta ccaatcattt tgaactcctg gttgcggtca tgttatcagc
    11941 ccagacgaca gatgcagcgg taaataaggc cacaccaggt ctctttgttg cctttccaac
    12001 accccaagct atgtctgtag cgacagagag tgagattgct tcacatattt ctcgcttggg
    12061 attgtatcgg aataaagcta aattccttaa aaaatgtgcc caacagttac tagacgattt
    12121 tgatggtcaa gtccctcaga cacgtgaaga attggagagt ttggcaggtg ttggtcgcaa
    12181 gacagccaat gttgtcatga gtgtaggatt tggaattcca gcctttgcag tggatactca
    12241 tgtggagcgt atttgcaaac accacgatat tgtcaaaaaa tcagcgacgc cacttgaggt
    12301 ggaaaagcgg gtcatggata tcttgccgcc tgagcagtgg ttagctgccc atcaggccat
    12361 gatttatttt ggaagagcca tttgccatcc aaaaaatcca gagtgtgacc agtacccaca
    12421 attatatgat tttagcaatt tgtaagatgc tacattgaaa ctttttgctt gattttaagc
    12481 atgctttgtg ctatagtaaa tgataactaa atattccttt aaacctgtcc cgtgaggcag
    12541 gcaaggagcg cgataaagta gaagggtgaa gtctatactg tgtgcagtag ggctcgcttg
    12601 gctataaatt tcaagtctcc ttgtttaagg agacttttct ttttggaggt ttgtcatgaa
    12661 aacaaaagaa gttgtagacg aattgaccgt caaacgagcg attacgcgta ttacttatga
    12721 gattatcgaa cgcaacaaag atttgaataa gatcgtcttg gctggtatta aaactcgtgg
    12781 tgtctttatt gcccaccgaa tccaagaacg tttgaagcag ttagaaaatc tttcagttcc
    12841 tgttgtggaa ttggatacta aacctttccg tgatgatgtt aaaagtggag aagatacttc
    12901 tttggtttct gtcgatgtga cagaccgcga agttatcttg gtggatgatg tgctctatac
    12961 aggtcgtacc atccgtgctg ctattgataa tattgtcggt catggtcgtc ctgcgcgtgt
    13021 gagtttagca gttctagtcg atcgtggaca tagagaattg ccaatccgtc cagattacgt
    13081 tggaaaaaat atcccaacca gtcgttctga agaaatcatc gtagagatga cagaacttga
    13141 tgaccaagac agagttctga ttactgaaga agcttagaaa gttaaaggag tagccatgtc
    13201 agaaaatcaa caagcattga accatgtggt gtccatggaa gacctcactg tcgatcaagt
    13261 aatgaaattg atcaagcgag gaattgagtt taaaaatgga gcccagcttc cctatgaaga
    13321 ccatccgatt gtttccaatc tcttctttga ggattctaca cggacacata agtcctttga
    13381 agtcgcagag attaaacttg gattggaacg acttgacttt gatgtgaaga ctagctcggt
    13441 taataagggt gagacacttt atgacaccat tttgactctg tctgctttag gagtggatgt
    13501 ctgtgtgatt cgccatccag aggtcgacta ctatagagaa ttgattgcta gtccaacgat
    13561 tacgacttcc atcatcaatg gtggagatgg ttcgggccaa caccctagcc agagcttgct
    13621 tgatttgatg accatttatg aggaatttgg ccactttgag ggtcttaaag ttgctattgc
    13681 aggtgacttg gaccactcac gcgttgccaa atccaatatg cagattttga aacgcttggg
    13741 agctgaactc tttttcgctg gacctgagga atggagaagt caagagtttg cagactatgg
    13801 acagtttgta accattgatg aaatcattga tcaggttgat gtcatgatgt ttctccgtgt
    13861 gcaacacgaa cgccatgata gtggagctgt attttcaaaa gaagactacc atgcccaaca
    13921 tggcttgact caagaacgtt acgatcgttt gaaagaaaca gcaatcctca tgcacccagc
    13981 tccaatcaat cgtgatgtag aaatagcaga ccacttggtt gaagcaccaa aatcacggat
    14041 tgtccaacaa atgaccaatg gtgtctttgt tcgaatggca atcttagaat ccgtactagc
    14101 gagtagaaac gccaactaaa acacaagacg ttaaaagacg ccagtgagcg tccacgagag
    14161 gtgaaaatat gacaaaaaga attctagtat tagaagatgg cacagttttt gaaggcaagg
    14221 ccttcggagc agatattgat gtaacaggcg aaatcgtctt taatacaggg atgaccggct
    14281 accaagaatc cattacagac cagtcttata atggacaaat cttgaccttt acttatcctt
    14341 tggtaggaaa ttatggtatt aatcgtgatg attatgaatc cattattcca acttgtaagg
    14401 gagtcgttgt ttttgaagaa gcgcgtagag ctagcaactg gcgcaaccaa atgaccttgg
    14461 atgaattttt gaaagccaag aaaattccag ggatttcagg aattgatacg cgtgctctta
    14521 ccaagattat ccgtaagcat ggtactatgc gtgcaacctt gacccatgtt ggggacagta
    14581 tggaccatgt gacggaccag ctccaagcaa cagttttacc gacagacaat atcaaacagg
    14641 tttctactaa aacgtcttat ccagctccag gagttggttt gagcgtggtg ctagtggact
    14701 ttggtctcaa gcactcaatc ctacgtgaac tttctaaacg caactgtaac gtgacagttg
    14761 ttccttattc gacaacggct gaagaaattc tccatctcaa tcctgacgga gttatgttgt
    14821 caaatggtcc aggtaaccca gaagacgttc cacaagcact cgacatgatt cgcggtgtac
    14881 aaggaaaaat tccaatcttt ggtatttgta tgggacacca actctttgca atggcaaacg
    14941 gggctaagac ctataagatg aagtttggcc accgtggatt caaccatgcg gtacgtgaaa
    15001 tcgcaacagg acgagtagac ttcaccagcc agaaccatgg ttatgcagtc agccgcgagg
    15061 atttgccaga gcacttgatt attacccacg aagaaatcaa tgacaagtca gtggaaggtg
    15121 tgcgccacag ataccaacct gctttctctg ttcaatacca cccagatgca gctcctgggc
    15181 cacacgacgc tagctaccta tttgacgagt ttatcgagat gatggaagtt tttaaacaat
    15241 caaactaaga acgagtaaaa gctcgtcgga gaatttatgt aactgaacac ggacggaaag
    15301 ctcagaatgt agagaaacca acttggattg tcaatccttc cttgatttcc taaaattcaa
    15361 tcgctttcta ttcgtccttt gtatcttatt taatgtcgcc ctgagaggcg acgaatagaa
    15421 aggagaaggg tgctccgtat ttgctgaact gaatacgggc tacggacggt gctaaaaaga
    15481 tagttattcc tagaactgac agttcttcgt cataactcct attttagctt tgtccgcttg
    15541 acacccttaa tatcttatat atgcctaaac gtactgatat tcaaaaaatt atggtgattg
    15601 gttctggtcc gattattatt ggtcaggctg ctgagtttga ctacgctggg actcaggctt
    15661 gcttgtcgtt gaaagaggaa ggttatgagg ttgttttggt taactcaaat cctgcaacca
    15721 tcatgacgga caaggaaatt gctgacaagg tttacattga accgattaca cttgagtttg
    15781 tgacacgtat tcttcgtaag gaaggtccag atgccttgct accaacactc ggtggtcaga
    15841 caggtctcaa catggccatg gaattatcta aaaatggtat cctagacgag cttggcgttg
    15901 aacttctggg taccaaatta tctgccattg accaagcgga ggaccgtgac ctctttaaac
    15961 aattgatgga agagcttgaa caacccattc cagaatctga aattgttaac acagtagaag
    16021 aagcagttgc ctttgcagcg acaattggct acccagtcat cgttcgtcca gcctttaccc
    16081 ttggtggtac tggtggtggt atgtgtgcca acgagaaaga attgcgtgaa atcactgaaa
    16141 atggtttgaa attgtcacct gttacccaat gtttgattga gcgttcgatt gccggtttca
    16201 aggaaattga atacgaagtg atgcgtgact cagctgacaa tgccttggtt gtttgtaaca
    16261 tggaaaactt tgacccagtt gggattcaca caggggattc cattgtattt gcccctgcgc
    16321 aaaccatgtc agactatgaa aaccaaatgc ttcgtgatgc gagcttgagc attattcgtg
    16381 ccctcaagat tgaaggtgga tgtaatgttc agctagctct tgatcctaac agcttcaagt
    16441 attatgttat cgaagtaaac cctcgtgtat cacgttcgtc agcccttgct tctaaagcga
    16501 caggatatcc gattgctaag ttggctgcca agattgcagt aggtttgacc ttggatgagg
    16561 ttataaaccc agttacaggt tcaacctatg ccatgtttga accagccctt gactacgtag
    16621 ttgctaagat tccacgtttc ccatttgaca agtttgaaaa gggtgaacgc cgtctcggta
    16681 cacaaatgaa ggcgactgga gaagtcatgg caatcggtcg taacatcgag gaatctcttc
    16741 tcaaggcctg ccgctccctt gaaattgggg tgcaccacaa tgaaatacct gaacttgcag
    16801 cagtttctga tgatgccttg attgaaaagg ttgtcaaagc ccaagatgac cgtctcttct
    16861 acgtatcaga agccattcgt cgtggctaca cacctgaaga aattgcagag cttacaaaaa
    16921 ttgatatctt ctatcttgat aaactcttgc atatctttga aattgagcaa gaattgggtg
    16981 ctcatccaca agatttagaa gttttgaaaa cagccaaact taatggtttt tcagaccgta
    17041 agattgctga actctgggga acgactgatg ataaagttcg ccaacttcgc ttggaaaaca
    17101 agattgttcc agtttataag atggtagaca cttgtgcggc agagttcgac tccgaaacgc
    17161 catatttcta ttcaacctat ggttgggaaa atgaatctat cagatctgat aaagaatctg
    17221 tacttgtcct aggttcaggt ccaatccgta tcggtcaagg ggttgagttt gactacgcaa
    17281 ccgttcactc tgttaaggct atccaggcag ctggttatga agctatcatc atgaactcaa
    17341 acccagagac cgtttcaaca gacttctctg tatcagataa gctttacttt gagccattga
    17401 cattcgaaga tgttatgaac gtcattgact tggaacaacc aaagggagtt atcgttcagt
    17461 tcggtggtca aacagccatc aaccttgcgg agccattggc aaaagcaggt gtgaccatcc
    17521 ttggtacaca ggttgctgac ctagatcgtg ccgaagaccg tgacctcttc gagcaagctc
    17581 tcaaagaatt ggatattcca cagccaccag gacaaacggc taccaatgaa gaagaagcag
    17641 ctcttgcagc tcgcaagatt ggcttcccag ttcttgtccg cccatcttat gtacttggtg
    17701 gacgtgccat ggaaatcgtt gaaaacgaag aagaccttcg ttcttacatg cgaactgctg
    17761 ttaaggctag tccagaccac ccagttcttg tcgactctta tatcgttggg caagagtgcg
    17821 aagttgatgc catttcagat ggtaaaaatg tactcattcc tggtatcatg gagcatatcg
    17881 aacgtgctgg tgtccactca ggtgactcaa tggctgttta cccaccacaa accttgtcgc
    17941 aaaaggttca ggagaccatc gcagactaca ccaaacgctt agcaatcggt cttcactgcc
    18001 ttggaatgat gaacatccag tttgttatca aggatgaaaa agtctacgtt attgaggtca
    18061 atccacgtgc cagccgtact gttccattcc tatctaaggt aaccaatatt cctatggctc
    18121 aagtagcgac caaactcatt cttggtcaaa gtttatcaga acttggctac caaaatggac
    18181 tttaccctga aagcacccgt gttcatatca aggcacctgt cttctccttt accaaactag
    18241 ctaaggtaga cagcttgctc ggtcctgaaa tgaagtcaac aggtgaagtt atgggttctg
    18301 atgctacttt ggaaaaagct ctctataaag cctttgaagc ttcttatcta cacttgccaa
    18361 cttttggtaa tgtcgtcttt accatcgctg atgatgccaa agaagaagcc ttgaacttgg
    18421 ctcgtcgttt ccaaaacatt ggttatggaa tccttgcgac agaagggaca gcagccttct
    18481 ttgctagtca tggcttgcaa gcccaacctg ttggtaagat tggtgatgac gataaggata
    18541 tcccaagttt tgtacgcaaa ggaagaattc aagctatcat taacacagta ggaacaaaac
    18601 gaactgctga cgaagatggt gagcaaattc gtcgttcagc cattgaacac ggggtgcccc
    18661 tcttcacagc gctagataca gctaatgcca tgcttaaggt acttgaaagt cgtagctttg
    18721 ttacagaagc gatttaaata gaaaaataag atatagcaga ctg
//
LOCUS       DAVKZI010000038        18752 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKZI010000038 DAVKZI010000000
VERSION     DAVKZI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.039"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            120..275
                     /locus_tag="VXB18_001634"
                     /pseudo
     CDS             120..275
                     /locus_tag="VXB18_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            475..3750
                     /gene="rexB"
                     /locus_tag="VXB18_001635"
     CDS             475..3750
                     /gene="rexB"
                     /locus_tag="VXB18_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0382811.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LEILFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLEQQGLENPAIPTSPSSKTLAKDTLQALY
                     PDKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3747..7397
                     /gene="addA"
                     /locus_tag="VXB18_001636"
     CDS             3747..7397
                     /gene="addA"
                     /locus_tag="VXB18_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0382812.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGIEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIDSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQCKRQENAFEFTDIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMNILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVTVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRKNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKEYPAAK
                     NGKLNSNTRLQGKNFQDWIWAISKVFTKDNLNFSYRFVGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7612..8790
                     /locus_tag="VXB18_001637"
     CDS             7612..8790
                     /locus_tag="VXB18_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382813.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSFIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8999..14890
                     /gene="iga"
                     /locus_tag="VXB18_001638"
     CDS             8999..14890
                     /gene="iga"
                     /locus_tag="VXB18_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEV0382814.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLTEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     SPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPAVKLTELY
                     LEEQFSKTKQNLGGSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     HHGTTDLFSALETYRKVFLPNTSNNDWFKKQTKAFIVEEKSTIAEVKAKQKQAGTKYS
                     IGVYDRITSNTWKYRNMVLPLLTLPERSVFVISTLSSLGFGAYDRYRNSEHKAGKDLN
                     NFVEENASETAKRQRDHYDYWYRILDNEGREKLYRTILLYDAYKFGDDTTSGKATVEA
                     KFDSSNPAMKNFFGPVGNKVVHNHHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPYDATITINSILKHSKSDSLEGSRLQVL
                     DPTERFQNSADLQNYVHNMFDLIYMLEYLEGQSIVKKLNVSQKMEALRKIENQYLTDP
                     ADGNEVYATNVVKELTEEEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEGIAKQNGQTINLYGK
                     KQGLVTDKLVLEKIFSGKYPSWTAFKKAMYQERIAQFDHLTKVIFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            14942..15145
                     /locus_tag="VXB18_001639"
     CDS             14942..15145
                     /locus_tag="VXB18_001639"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0382815.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVRNSFLLPLKSHHLMAFFYIG"
     gene            15338..16189
                     /gene="ylqF"
                     /locus_tag="VXB18_001640"
     CDS             15338..16189
                     /gene="ylqF"
                     /locus_tag="VXB18_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0382816.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16176..16955
                     /locus_tag="VXB18_001641"
     CDS             16176..16955
                     /locus_tag="VXB18_001641"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0382817.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            16971..18521
                     /locus_tag="VXB18_001642"
     CDS             16971..18521
                     /locus_tag="VXB18_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0382818.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMSDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVRNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         6108 a         3658 c         3880 g         5106 t
ORIGIN      
        1 gattgaaata agatacgaac agcttgatta gggaaatcaa attaatttct agaaatattt
       61 tagcatccac ggtgtactgt tatagtttca atttactata gttcaatcat tctatcaaga
      121 atattgaata tataaaggca cgtaatatta aaacttcttc tgatatcgaa ttagagtccg
      181 atgttgattg cgataaatca gacaatctac ccgtcgacat taagatactg ggacaacaca
      241 ttgaagtgta ttccgtacct aagaaacaat cataaaactc aaagccttgt taccgaggct
      301 tttttattat gtgattttca gtagccagac ttattctatc taatacaagt aaagctaagt
      361 atttaagatt tagcagatga tgaagaaaag aaaggatggc ctaaatattt taacagattt
      421 acgaggctaa tcatggtata atatagggtg atgaaaaatt ccaacgaggc tgagatgaaa
      481 ttactttata ctgatattcg gacttctttg acagaaattc taacaagaga ggcagaagag
      541 ctagttgcag ctggcaagcg ggtcttctac attgccccca actctctttc ttttgaaaag
      601 gaacgcgccg tgctggaata cttgtcccag caggcttctt tttcgattac cgtcacgcgc
      661 tttgctcaaa tggctcgcta tctggtcttg aatgatttac cagctaaaac tactcttgat
      721 gatatcggtc ttgggttggc cttttacaaa tgccttgccg aactcgatcc caaggacttg
      781 cgtgtttatg gcgctattaa gcaggatcct caattgatcc agcagttaat tgagctttac
      841 catgagatga ccaaatctca gatgagtttt ttggacttgg agaatttaac agatgaggat
      901 aagagggcgg atttactctt gatttttgag aaagtaacag cctatcttaa tcaaggtcag
      961 ttagcccagg gaagtcagtt gtcccatttg attgaggcta ttgagaatga caaggtaagt
     1021 agtgatttta atcaaatcgc cttggtcatt gacggcttta ctcgtttttc tgctgaggaa
     1081 gagcgggttg tggacttact tcacggcaaa ggtgttgaga ttgttatcgg ggcttatgct
     1141 agtaagaaag cctataccag tccttttagc gagggcaatc tctaccaagc cagcgtaaaa
     1201 tttctccatc atctggcttc taaataccaa acgcctgctc aggactgttc tcaaactcat
     1261 gagaagatgg atagttttga caaggcctct cgtttgttgg agtcttctta tgacttttca
     1321 gaactcgctt tggatgtcga tgagaaagac cgtgaaaatt tacaaatctg gtcttgtttg
     1381 acgcaaaagg aggagttgga gctagtagcc cgtagtattc gtcagaaatt acatgagaac
     1441 tcagacctga gctacaagca ttttcgtatt ctcttggggg atgtagcttc ttaccagtta
     1501 tctctcaaaa ccatttttga ccagtatcag attccttttt atcttggtag aagcgaagcc
     1561 atggctcatc atcccttgac tcagtttgtc gagtctattt tagctttaaa acgttaccgt
     1621 tttcgtcagg aggatttgat taatcttctt agaactgatt tgtatactga cctcagtcag
     1681 tctgatattg atgcttttga gcaatatatc cgctatcttg gtatcaatgg cttgccagcc
     1741 tttcagcaaa ccttcaccaa atcccaccat ggaaaattta atcttgagcg tttgaatgtc
     1801 ctccgcctga gaattttagc acctcttgaa atcctctttg ccagccgaaa acaaaaggct
     1861 gaaaaactcc tacaaaaatg gagtgtcttt ctaaaagaag gagctgtgac caagcagtta
     1921 caagatttga caaccacttt ggaagctgta gaacaggaaa gacaagccga agtttggaag
     1981 gctttctgcc atgttttaga acaatttgcg actgtttttg ctggttcaca ggttagtctg
     2041 gaagacttcc tagccttgct ccattctgga atgagtttgt cccaataccg taccattcca
     2101 gcaacagtgg acactgttct ggtgcagagt tacgatttga ttgcaccatt gactgctgac
     2161 tttgtctatg ctattggact aactcaggac aatttaccaa aaatttctca aaacaccagt
     2221 cttctgacag atgaagaaag gcaaaatcta aaccaagcga ccgaagaagg cgttcaatta
     2281 ctgattgcca gcagtgaaaa tctcaagaaa aatcgctaca ctatgctttc cttggtcaat
     2341 tctgctcgta agcagttgtt cttgtcggct ccaagccttt ttaacgaaag tgaaagtaag
     2401 gaatctgcct atcttcaaga gttgatccat tttggattta ggcggagaga gaagaggatg
     2461 aatcacaaag gactgtctaa ggaggatatg gggtcctatc acagtctttt gtctagtctg
     2521 gttgcctatc accagcaggg tgagatgagc gatactgagc aagatttgac ttttgtcaag
     2581 gttttgtcgc gtgttatagg taaaaaacta gagcagcaag gtctggaaaa tccagccatc
     2641 ccaaccagtc caagcagcaa gaccttagcc aaggacacct tgcaagctct ctatcctgac
     2701 aaacaggagt tttacctgtc tacgtcgggt ttgacagagt tttatcgcaa tgaatacagt
     2761 tatttcctac gctacgtttt aggcttgcag gaggaattac gtttgcgtcc tgatgcccgt
     2821 agtcacggga atttcttgca tcgtatcttt gaacgcgcct tgcagttgcc taatgaagat
     2881 tcctttgacc aacgtctaga acaagctatt caagaaacca gtcaagaacg cgaatttgaa
     2941 gctatttatc aagaaagttt ggaagcccag tttaccaagg aagttttgct tgatgttgca
     3001 cggacaactg gacatattct ccgacacaat ccagccatcg aaaccatcaa agaagaagca
     3061 aattttggtg gaaaagacca agcctttatt caattagaca atggacgcag tgtctttgta
     3121 cgaggcaagg tggaccggat tgaccgtttg aaagctaatg gagcgatagg agtagtagac
     3181 tacaaatcca gtctgactca gttccagttt cctcatttct ttaatgggct caattctcag
     3241 ttaccaacct atcttgctgc cctaaaaaga gaaggggagc agaacttttt cggcgccatg
     3301 tacttggaaa tggctgaacc tgtccaatct ctgatggcgg taaaaagtct ggcaggagca
     3361 gtggtagaag ccagcaaatc tatgaaatac caagggctct tcttggaaaa agaaagcagt
     3421 tatttaggcg aattttataa caaaaacaag gctaatcaac tgacagatga ggaatttcag
     3481 ctcctactgg actacaatgc ctatctttac aagaaagctg ctgagaagat tttagcaggc
     3541 cggttcgcca tcaatcctta tactgaaaat ggcagaagca ttgccccata cgtccagcaa
     3601 catcaggcta ttacaggctt tgaagccaat taccatctgg gccaagcccg tttcctagaa
     3661 aagttggacc tagctgatgg caagcgtctg gtcggagaaa aactcaagca agcttggctt
     3721 gaaaaaataa gagaggagtt gaatcgatga agcttattcc ctttttaagt gaggaggaga
     3781 ttcaaaaact gcaagaagca gaagcaaatt cgagcaaaga acagaagaaa actgccgagc
     3841 aaatcgaagc tatctacact tctggtcaga atatcctggt ctcagcatcg gctggttctg
     3901 gaaagacctt tgtcatggca gagcgcattc tggaccaatt ggcgcgtggt atcgaaattt
     3961 ctcaactctt tatctcaacc tttaccgtca aggctgcaac tgaacttaaa gaacgtttag
     4021 agaaaaaaat cagcaagaaa atccaagaaa cagatgatgt cgacctcaaa caacacttgg
     4081 gtcgccagtt ggcagaccta cccaacgctg ccatcggaac catggactct ttcacacaaa
     4141 aattccttgg caaacatggt tatctgcttg atattgcacc taatttccgt attttacaaa
     4201 accaaagcga gcaacttctg ctcgaaaacg aagtctttca tgaggtcttt gaagcgcatt
     4261 accaaggtaa acagaaagag acctttagtc atttgctgaa aaactttgct gggcgtggca
     4321 aggacgaacg gggtctgcgc cagcaggtct ataaaatcta tgacttcctc caatccacca
     4381 gtaatcctca aaagtggctg agtgaatctt tcctcaaagg atttgagaaa gctgatttta
     4441 ccagtgaaaa agaaaaactg actgagcaga tcaaacaagc cctttgggat ttggaaagct
     4501 ttttccgtta ccatctggat aacgatgcca aggagtttgc aaaggctgcc tatttagaaa
     4561 atgttcagtt aattctggat gaaattgact ccctaaatca ggagtccgat agtcaggctt
     4621 atcaggcagt gcttgcgcgt gttgtcgcca tctctaagga gaaaaacggt cgagctctga
     4681 ctaatgccag tcgtaaggct gatttgaagc ccctggctga tgcctacaac gaagagagaa
     4741 agacccagtt tgctaaacta ggacaattat cagaccagat aaccattctc gactatcaag
     4801 aacgttatca tcaagacaca tgggaactag ctaaaacctt ccaaaccttt atgagtcatt
     4861 ttgtggaggc ttatcgtcag tgcaaacgcc aggaaaatgc ctttgaattc actgatatca
     4921 gccattacac cattgagatt ttagagaatt tcccacaagt tcgtgagtct tatcaggagc
     4981 gcttccatga agtcatggtc gatgagtatc aggataccaa ccatattcaa gaacggatgc
     5041 tggaattgtt gtctaatggc cacaatcgct ttatggtggg agatatcaag caatccatct
     5101 atcgtttccg tcaggcagac ccgcagattt tcaatgagaa attccaacgc tatgcgcaaa
     5161 atccccaaga aggcaagctc attctcctca aggaaaattt ccgtagtagt tcagaagtgc
     5221 tgtcagcaac caatgatgtc tttgaacgtc tcatggacca agaggtcggc gaaatcaact
     5281 atgataacaa gcaccagctt gtttttgcca ataccaaact gactcccaat ccagacaaca
     5341 aggcagaatt tctcctctac gacaaggacg atacaggtga ggaagaagag agtcaaacag
     5401 aaacgaaact aacaggcgaa atgcgcttag ttatcaagga gattctgaaa cttcatcaag
     5461 aaaaaggtgt tgcctttaag gaaattgccc ttctgacctc cagccgcagt cgtaatgacc
     5521 agattctcct cgccctgtct gagtacggga ttcctgtcaa aactgacgga gagcaaaaca
     5581 attatctcca atccctagaa gtgcaagtca tgctagacac tcttcgtgtc attcacaatc
     5641 ccctgcaaga ctacgccttg gttgccctta tgaagtctcc aatgtttggt tttgatgagg
     5701 atgagctagc acgtttgtcc cttcagaaag cagaggataa agtccacgaa aatctctatg
     5761 agaaactggt caatgcacaa aaaatggcaa gtagtcaaaa aggcttgatt cacacagctc
     5821 tagctgaaaa actaaagcaa ttcatgaata tcctagcttc ttggcgcttg tatgccaaaa
     5881 cccactctct ctatgacttg atttggaaga tttacaacga ccgtttttat tatgactatg
     5941 ttggggcttt gccgaatggt cctgctaggc aggccaatct ctatgcccta gcactgcgtg
     6001 ctgatcaatt tgaaaagagc aatttcaaag gtttgtcgcg ttttattcgt atgattgacc
     6061 aagttttaga agcccagcac gatttggcaa gcgttacagt tgcaccacct aaggacgcag
     6121 tagagctcat gactatccac aagagtaaag ggctagagtt tccttacgtc tttattctca
     6181 atatggatca agatttcaac aagcaagact ctatgtcaga agtcattctc agccgtaaaa
     6241 acggtctagg tgtcaagtat attgccaaaa tggagactgg agcagtggaa gatcactatc
     6301 ctaaaaccat caaactctcc attcctagtc tgacctatag gcagaacgaa gaggaattac
     6361 agctagcaag ctattcagag cagatgcgtc tcctttatgt tgccatgacg agggctgaga
     6421 aaaaactcta tcttgtcggc aagggttctc gtgaaaagct ggaagccaag gaatacccag
     6481 cagctaaaaa tggaaaacta aatagcaaca ctagacttca aggcaagaat ttccaagatt
     6541 ggatttgggc tatcagtaaa gtgtttacta aggacaatct caactttagt tatcgttttg
     6601 ttggagaaga tcagttgact agagaagcta tcggagagtt ggaaaccaag agtcctctcc
     6661 aagatagctc ccaagcagac aatcgtcagt cagataccat caaagaagct ctggaaatgc
     6721 tgaaggaggt ggaagtttat aatactcttc accgcgcagc tattgaactt cctagtgttc
     6781 aaaccccaag tcaaatcaag aaattctacg aaccagttat ggatatggaa ggtgtcgaga
     6841 ttgctggtca aggtcagtca gtaggcaaga aaatcagctt cgatttgcca gatttttcaa
     6901 ccaaagaaaa ggtaactgga gctgagattg gtagtgctac tcacgaactc atgcagagaa
     6961 ttgacctcag ccagcaacta acccttgcta gcctaacaga aacactcaaa caagttcaaa
     7021 ctagccaagc tgtcagagac aagatcaatc ttgataaaat tcttgctttc tttgacacag
     7081 tactcggtca ggaaattctt gctaataccg accatcttta tcgcgagcaa cctttctcca
     7141 tgctcaaacg agaccaaaag agtcaggaag actttgttgt ccgtggtatc cttgatggct
     7201 atctgcttta cgaaaacaaa attgttctgt tcgactacaa gacagaccgc tatgatgaac
     7261 caagtcaact cgtagaccgc tatcgtggtc agttagctct atacgaagag gctttatcac
     7321 gagcctattc gattgaaaat attgaaaaat acttgatttt actcggtaaa gacgaggttc
     7381 aagttgtaaa agtataactt atactctttg aaaatctctt caaaccacgt cagcttcgcc
     7441 ttgctgtata tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
     7501 gagctgactt cgtcagttct atctacaacc tcaaaacagt gttttgagct gactgcggct
     7561 agctttctag tttgctcttt gatttttatt gagtattaga aaggagacct catgacactt
     7621 ccagttagaa aatccctgca cgatgcagtt ttacaggctt cgaaagcgga tacttgggaa
     7681 caagctacca aggaatggaa tgaagtttcc tttattttta acggtatcgg ccgtagcaat
     7741 tgtgtctgtg gaaatgccat caaatacgct tatgaactct ttaacggtgt cacaggccaa
     7801 cgcctctttc caattggtag cgactgtgtt cgtcattttc atcgattgtc ccttgaccag
     7861 caattggaag aggaagaaaa actgctcaga aaggttgaaa atctaaccag aaaagctcag
     7921 aaaaaggaaa aaatcaaggt caataaaagt aactttgacg agcgacttct aaaatggctc
     7981 tgggaaaaag gtgttttcaa acccaatcgt ggcaatcaat ttgcgcctga gagagactac
     8041 cagcttttcc tagaagtctt tcagggagga agttggacca aggcggaacc aaagaaaaag
     8101 gctcggatgg aagaagtcct tgaaaagtgt atcaaaccct ttttacttgg gaaatcggat
     8161 gaccaactct accttgtcaa gctaggcaag gagaaaattg actacgaaca agaactccgt
     8221 atccaggcag agaaagaacg caagaagagg gataaaatcg ccaagcaata tgcagacaat
     8281 ctggttctag ccatgggacc cgcagagcgt gcttatcaag attactttgg ctttacagag
     8341 accctgactc aagaagaacg caagtgggaa aaaattcttt ttggtaaaaa tagagcagaa
     8401 cgagctatca aggccaaaca ataccaaaaa gagctggaaa aagaccaacg aattgccagt
     8461 caggatccaa ttgaaagaaa acagaagcag acttggatcc tcaattccta ttttcgtgag
     8521 cttcctgaag aaaaagctcg attttctaga ctcttattag aatatcgaaa aagtggtgaa
     8581 gtaccctttt caactgaata cctgtcagat catctcatcg actttttcta taaaatgaaa
     8641 gcctttgaat ttgaaatcgc accagaacaa gtccgagatt ttctaaaaaa aagcctgcag
     8701 gaagaccatc gctcatcagc acaaggaagc tggatagaag gaattctcct caactgcctc
     8761 aaaccatttt tagaacgatt agtgatatga gtaacaccta ccgtgtaaat ttcatggtag
     8821 gtgttattgt acccccaaat aatataaaac aaagtatgaa agcgcatctc aattttaaga
     8881 cttttttgta aattaagagt ataattaagg tatactgcct tttctataga taatagataa
     8941 tacactaata taataaaggt ctttgtaaca tatataaatt ttatttcaag gaggaataat
     9001 ggaaaagtat tttggtgaaa aacaagagcg tttttcattt agaaaattat cagtaggact
     9061 tgtatctgca acgatttcaa gtttattttt tatgtctgta ttagctagtt catctgtgga
     9121 tgctcaagaa actgcgggag ttcactataa atatgtggca gattcagagc tatcatcaga
     9181 agaaaagaag cagcttgtct atgatattcc gacatacgtg gagaatgatg atgaaactta
     9241 ttatcttgtt tataagttaa attctcaaaa tcaactggcg gaattaccaa atactggaag
     9301 caagaatgag aggcaagccc tagttgctgg tgctagctta gctgctctgg gaattttaat
     9361 ttttgctgtt tccaagaaaa aggttaagaa taaaacggta ttacatttag tattggttgc
     9421 gggaatggga aatggtgtct tagtttcagt ccatgcttta gaaaatcatc ttttgctaaa
     9481 ttacaatacg gactatgaat tgacctctgg agaaaaatta cctcttccta aagagatttc
     9541 aggttacact tatattggat atatcaaaga gggaaaaacg acttctgatt ttgaagtaag
     9601 taatcaagaa aaatcagcag ccactcctac aaaacaacaa aaggtggatt ataatgttac
     9661 accaaatttt gtagaccatc catcaacagt acaagctatt caggaacaaa cacctgtttc
     9721 ttcaactaag ccgacagaag ttcaagtagt tgaaaaacct ttctctactg aattaatcaa
     9781 tccaagaaaa gaagagaaac aatcttcaga ttctcaagaa caattagccg aacataagaa
     9841 tctagaaacg aagaaagagg agaagatttc tccaaaagaa aagactgggg taaatacatt
     9901 aaatccacag gatgaagttt tatcaggtca attgaacaaa cctgaactct tatatcgtga
     9961 ggaaactata gagacaaaaa tagattttca agaagaaatt caagaaaatc ctgatttagc
    10021 tgaaggaact gtaagagtaa aacaagaagg taaattaggt aagaaagttg aaatcgtcag
    10081 aatattctct gtaaacaagg aagaagtttc gcgagaaatt gtttcaactt caacgactgc
    10141 gcctagtcca agaatagtcg aaaaaggtac taaaaaaact caagttataa aggaacaacc
    10201 tgagactggt gtagaacata aggacgtaca gtctggagct attgttgaac ccgcaattca
    10261 gcctgagttg cccgaagctg tagtaagtga taaaggcgaa ccagaagttc aaccgacatt
    10321 acccgaagca gttgtgaccg acaaaggtga gactgaggtt caaccagagt cgccagatac
    10381 tgtggtaagt gataaaggtg aaccagagca ggtagcccca ttgacagaat ataagggtaa
    10441 tattgagcaa gtaaaacctg aaactccggt tgagaagacc aaagaacaag gtccagaaaa
    10501 aactgaagaa gttccagtaa aaccaacaga agaaacacca gtaaatccaa atgaaggtac
    10561 tacagaagga acctcaattc aagaagcaga aaatccagtt caacctgcag aagaatcaac
    10621 aacgaattca gagaaagtat caccagatac atctagcgaa aatactgggg aagtgtccag
    10681 taatcctagt gattcgacaa cctcagttgg agaatcaaat aaaccagaac ataatgactc
    10741 taaaaatgaa aattcagaaa aaactgtaga agaagttcca gtaaatccaa atgaaggcac
    10801 agtagaaggt acctcaaatc aagaaacaga aaaaccagtt caacctgcag aagaaacaca
    10861 aacaaactct gggaaaatag ctaacgaaaa tactggagaa gtatccaata aacctagtga
    10921 ttcaaaacca ccagttgaag aatcaaatca accagaaaaa aacggaactg caacaaaacc
    10981 agaaaattca ggtaatacaa catcagagaa tggacaaaca gaaccagaga aaaaactcga
    11041 attaagaaat gtttctgata ttgagttgta tagtcagacg aatggaacct acagacaaca
    11101 tgtttcattg gatggaattc cagagaatac ggatacttac tttgtcaagg taaaatcttc
    11161 agcatttaaa gatgtctata taccagtagc ttcaataacc gaagagaaaa gaaatgggca
    11221 gtcagtttat aaaatcacag ccaaagctga gaaactccag caagaactag aaaataaata
    11281 tgtcgacaat ttcaccttct acctcgataa gaaggctaaa gaggaaaata caaactttac
    11341 ttcctttagc aacctggtca aagctataaa ccaaaatccc tctggaacct atcatttagc
    11401 ggccagcctg aatgctaacg aagtggagct tggtcctgat gaaagatcct atatcaagga
    11461 cacctttact ggtcgtttaa tcggtgaaaa agatggcaag aattatgcta tctataattt
    11521 gaaaaaacct ctgtttgaaa acttgagtgg tgctacagta gaaaaactga gtctaaaaaa
    11581 tgttgctatt tcagggaaaa atgatattgg ttcactggca aatgaagcta cgaatggcac
    11641 aaagattaaa caagttcatg ttgatggtgt tctggctgga gaacgtggtg tcggtggttt
    11701 gttggctaag gcagaccaat caagcatcgc agagagcagt ttcaagggaa gaattgtcaa
    11761 tacctatgaa acgactgatt cctacaatat tggcggtctg gtcggtcatt taacaggaaa
    11821 aaatgcgtct attgctaaat ccaaagcgac agtaaccatt tcgtcaaaca ccaataggtc
    11881 agatcagact gtcggtggtc ttgcaggtct agtagaccga gatgcacaga tccaagatag
    11941 ctatgctgaa ggtgatatca acaatgtcaa gcactttggt agagtcgctg gagtggcagg
    12001 caatttgtgg gatcgaactt ctggtgatgt taggcatgct ggaagtttga caaatgttct
    12061 cagcgatgtt aatgtaacaa acggaaatgc catcactgga taccactata caggaatgaa
    12121 ggtagctaat acatttagta gtaaggctaa tagagttttc aatgtcactt tagagaagga
    12181 tgaggtcgtc agcaaggaat cctttgaaga aagaggaaca atgctagatg cttctcaaat
    12241 tgtaagcaaa aaagcagaaa taagtcctct cactctacca acggtggaac ccctctcaac
    12301 aagtggcaag aaagacagtg atttttctaa gatagcccat tatcaagcta accgtgcttt
    12361 ggtttataag aacattgaaa aattgttacc tttttataat aagtcaacca tcgtgaaata
    12421 cggaaacctg gttaaggaga acagtctctt ataccaaaaa gaactcttat ctgcagttat
    12481 gatgaaggat gaccaagtaa tcacagatat tgtttccaac aaacagactg caaacaaact
    12541 cttacttcac tataatgacc attcatctga gaaatttgat ctcaagtacc agactgattt
    12601 tgccaatcta gcagaatata atctaggtaa tacgggactt ctctacactc ctaaccaatt
    12661 cttatatgat cgagactcta ttgttaagga agtcttgcct gagttgcaga agcttgatta
    12721 ccagtcagat gctatcagaa agacacttgg tatttctcca gcagttaagt taaccgagct
    12781 ctatttagaa gagcagttct ccaaaacaaa acaaaatctg ggaggcagct tgaaaaaact
    12841 tttgtcagca gatgccggtc tagctagcga taactcagtc accagaggct atcttgtaga
    12901 taaaatcaag aataataagg aagccttgct actcggttta acttatttag aacgttggta
    12961 taactttaac tatggtcaag tgaatgtcaa agacctagtt atgtatcatc cagacttctt
    13021 tggtaaagga aatacttccc cactagatac tctgattgag ttaggtaaat ctggctttaa
    13081 caatcttctt gccaagaaca atgtcgatac ttatggtatc agtctagcca gccatcatgg
    13141 aacgacagat ttgtttagcg cacttgaaac ttaccgaaaa gtctttttac caaacactag
    13201 caacaatgac tggtttaaaa aacagaccaa agctttcatt gtcgaagaaa aatccactat
    13261 tgcagaggtc aaagccaagc aaaagcaagc aggaactaag tactctatcg gtgtttatga
    13321 ccgaattact agtaatactt ggaagtaccg gaatatggtc ttgcctctcc ttaccttgcc
    13381 agaaagatct gtatttgtca tctcaacctt gtctagtcta ggatttggtg cttacgatcg
    13441 ctaccgtaat agtgaacata aagcaggcaa ggacctcaat aatttcgttg aagaaaatgc
    13501 gagtgaaact gccaaacgtc agcgagatca ctacgattat tggtatcgca ttttagataa
    13561 tgagggacgt gaaaaactat atcgtacgat tctcctttat gatgcctata agtttggtga
    13621 tgacacaaca tctggaaaag ctacagtgga ggctaagttt gatagctcca atccagccat
    13681 gaagaatttc tttggtccag ttggtaataa ggttgttcat aatcatcacg gtgcctacgc
    13741 aacaggagat ggtgtctact atatgtctta ccgcatgctc gacaaggatg gagccattac
    13801 ctatacccat gagatgaccc atgattcgga tcaagatatt taccttggcg gctatggtcg
    13861 aagaagtggt cttggtcctg agttctttgc taaaggttta ttacaagcgc cagaccatcc
    13921 atatgatgcg accattacca ttaactctat cttgaaacat tcaaaatcag atagcttaga
    13981 aggatcgcgt ctgcaagtct tggatccgac agaaagattc caaaactcag cagatcttca
    14041 aaactatgtt cacaacatgt ttgacctcat ctatatgttg gaatatctag aagggcaatc
    14101 gattgttaag aaactgaatg tttctcagaa aatggaagct ctcagaaaaa tcgagaatca
    14161 atatctaaca gatcctgctg atggaaatga ggtttacgct actaacgtag tcaaagaatt
    14221 gacagaagaa gaggcccgaa acctgaatag ttttgatagt ttgattgaca ataatattct
    14281 ttcagctcgt gagtataagg ctggtacata tgagagaaat ggctacttta ctataaaact
    14341 ctttgcacca atcttttcag cattgagcag tgagaaaggt actcctggag atcttatggg
    14401 acgaaggata gcttatgaac tcttagctgc taaaggattt aaagatggta tggtaccata
    14461 tatttccaac caatatgaag gaattgctaa acaaaatggt cagacaatca acctttacgg
    14521 taaaaagcaa ggattagtga cagataagct tgttttggaa aagatattct ctggcaagta
    14581 tccatcttgg acagccttta aaaaagctat gtatcaagag cgtattgctc agtttgatca
    14641 tttgactaaa gttattttta aagatccgac aaaaccatgg ccaagctatg gcacaaagac
    14701 tatcaataat gtggatgaat tgcaagccct catggaccaa gctgttctca aggatgctga
    14761 aggtccacgt tggagtaatt ataatccaga aatcgacagt gccgttcata agttgaagag
    14821 agcaatcttt aaagcctatc ttgaccaaac aaatgatttt agaagttcaa tttttgagaa
    14881 taaaaaatag tgtttactat taggaaataa agtttaaaaa ggtgatgaag aacaaaccaa
    14941 gattcaagca ggaattccta ctgataatga agtaagttat gctcttattt atcagcagga
    15001 aactcttcct gcaacaggtt catcaacttc tgcgcttaca gctttaggcc tattagctgt
    15061 tggtagttta gttcttttgg ttcggaacag ttttttgctc cctctgaaaa gtcatcattt
    15121 gatggctttt ttctatatag gatagggtat agggtaaaag atagggtaaa aggctatcat
    15181 cggacaaaat aaagaaggca tgatataata taaagtagat ttctatgtca taaaacaaga
    15241 actgtttgga catcattcat ttgaaaactc tctatgttca aactatagta aaataaaata
    15301 ggggatctaa atccttgcta tgaaaggaaa aaactcaatg gctactattc aatggtttcc
    15361 tggtcacatg tctaaagctc gtcgacaggt gcaggagaat ttaaaatttg ttgattttgt
    15421 gacgatttta gtagatgcac gcttgcctct atctagtcaa aatcctatgt tgaccaagat
    15481 tgttggtgat aaaccaaaac tcttgatttt aaacaaggcc gacttggctg atccagcaat
    15541 gaccaaggaa tggcgtcagt attttgaatc acaaggaatc cagacgctag ctatcaactc
    15601 caaagagcaa gtgactgtaa aagttgtaac agatgcggcc aagaagctca tggctgataa
    15661 gattgctcgc cagaaagaac gtgggattca gattgaaacc ttgcgtacca tgattatcgg
    15721 gattccaaac gctggtaaat ccactctgat gaaccgtttg gctggtaaaa agattgctgt
    15781 tgttggaaac aagccagggg tcacaaaagg tcaacaatgg cttaaaacca ataaagatct
    15841 ggaaatcttg gatacaccgg ggattctctg gcctaagttt gaggatgaaa ctgttgcact
    15901 taagttggca ttgactggag ctatcaagga tcagttgctt cctatggatg aggttaccat
    15961 ttttggtatc aattatttca aagaacatta tccagaaaag ctggctgaac gcttcaaaca
    16021 aatgaaaatt gaagaagaag cgcctgtgat tattatggat atgacccgcg ccctcggttt
    16081 ccgtgatgac tatgaccgtt tttacagtct cttcgtgaag gaagtccgtg atggcaaact
    16141 cggtaactat accttagata cattggaaga cctcgatggc aacgattaaa gaaatcaaag
    16201 aactccttgt gacagtcaag gagttagaaa gccctatttt tttagatctt gaaaaggata
    16261 atcgctcagg agttcaaaag gaaatcagca agcgtaaaag agccattcaa gctgaattag
    16321 atgaaaattt gcgcttggaa tccatgcttt cttatgaaaa agaactttat aagcaaggat
    16381 tgaccttaat tgcaggtatt gatgaggttg gtcgtggtcc tcttgctggt cctgtagtcg
    16441 ctgcggccgt tattttacct aaaaattgta agattaaagg tctcaacgac agcaagaaaa
    16501 ttcctaaaaa gaaacatctg gagattttcc aagccgttca agaccaagcc ttgtcgattg
    16561 gaattggtat catagataat caggtcatcg accaagtcaa catctatgaa gcaaccaaac
    16621 tagccatgca agaagcaatc tcccagctca gccctcaacc agagcacctt ttgattgatg
    16681 ccatgaaact ggacttgccc atttcacaaa cctccattat caaaggagat gccaactccc
    16741 tctctatcgc agcagcatct atagtagcca aggtaacacg tgatgaattg atgaaagaat
    16801 acgatcagca gttctctggc tatgatttcg ctactaatgc aggatatggc acagctaaac
    16861 atctggaagg cctcacaaaa ctaggagtta ccccaattca ccgaaccagc tttgaacccg
    16921 ttaaatcact ggttttaggt aaaaaagaaa gttaattgaa aggaaatacc atggaggaac
    16981 agtcggaaat agtccgttct aagaaagaat tcgcctttgc atccagcact atactatccc
    17041 aagttggtcg aggaatcatt gtcggcctca tcgttggaat tatcgtcgga tcctttcgtt
    17101 tcttaattga aaagggcttc cacctgatac aaggagttta tcaagatcaa gggtacttag
    17161 tgcgcaatct ttttgtactg gttttgtttt atatactcat ctgttggctc agtgccaaac
    17221 taacacggtc agaaaaagat attaaaggct caggaattcc tcaagtcgaa gccgaactga
    17281 aaggcctcat gtccctcaac tggtggggca ttctttggaa aaaatatgtg ctaggtattc
    17341 ttgctattgc cagtggactc atgctgggtc gagagggacc cagcattcaa cttggagcag
    17401 ttggtggtaa aggaattgcc aagtggctca aatccagtcc agtagaggaa cgttccttga
    17461 ttgccagtgg agctgcagca ggtttagccg cagcctttaa tgctcctatt gcagcacttc
    17521 tctttgttgt agaagaagtc tatcaccatt tttcgcgctt tttctgggtc tcaactctag
    17581 cagccagcat cgtagcaaac tttgtgtctc tactcatgtt cggtttgaca ccagtattgg
    17641 atatgtcaga taacattcct cccatgaccc tagaccagta ttggatatat ctcgtcatgg
    17701 gaattttcct tggattttca ggttttctct atgagaaagc tgtattaaac gttggaagag
    17761 tttatgactt gattggtcaa aaaatccatt tggatagggc ttattatccc atcttggctt
    17821 ttatccttat cataccagtc ggaatcttct tacctcaaat ccttggtggc ggaaatcagc
    17881 ttgtcctttc tttaactgaa caaaatttta gtttccaagt tttattagct tactttttga
    17941 tccgctttat ttggagtatg attagctatg gaagtggact gccaggagga attttcctac
    18001 ccattttagc tcttggttct ttgcttggtg ccttagttgg tgttatctgt gtcaatcttg
    18061 gacttgtcag tcaagagcaa ttccctatat ttgtcattct aggaatgagt ggctattttg
    18121 gagccatatc aaaagctccc ttaaccgcta tgatcctcgt aactgagatg gtaggagata
    18181 ttcgcaacct catgccactt ggtcttgtca ctcttgtttc ttatattatc atggatttgc
    18241 tcaaaggtac gccagtctat gaagccatgc tggaaaaaat gcttccagaa gaagtatcta
    18301 gcgaaggaga agttacactt atcgaaatac cagtttctga taaaattgct gggaaacaag
    18361 ttcatgaact caacttacca cacaacgtcc tcatcacaac tcaagtccgt aatggcaaga
    18421 gccaaacagt taacggctca accagaatgt atctgggtga tatgattcac ctggttattc
    18481 caaaaagtga aattggaaaa gtcaaagatt tgttgttgta gtatgatcat tcacataatt
    18541 tatgttatgt aaatgatcag tttgatttat ttagaaaacc gattctcaga aatgagatcg
    18601 gttatttttt actgatgagg aattttacat ataaataatt gaactttatt aaaaataaga
    18661 ctataattaa gttagaaatg ataaagcata aagctggaaa ggagtttact gtatcaaatc
    18721 tgtacagtaa gattaaaatc atgaaaaaga aa
//
LOCUS       DAVKZI010000039        18588 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKZI010000039 DAVKZI010000000
VERSION     DAVKZI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.040"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(81..890)
                     /locus_tag="VXB18_001643"
     CDS             complement(81..890)
                     /locus_tag="VXB18_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0382819.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLIIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(892..1695)
                     /locus_tag="VXB18_001644"
     CDS             complement(892..1695)
                     /locus_tag="VXB18_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0382820.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1705..3192)
                     /gene="tacF"
                     /locus_tag="VXB18_001645"
     CDS             complement(1705..3192)
                     /gene="tacF"
                     /locus_tag="VXB18_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0382821.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYSYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3527..4234
                     /locus_tag="VXB18_001646"
     CDS             3527..4234
                     /locus_tag="VXB18_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0382822.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4239..5261
                     /locus_tag="VXB18_001647"
     CDS             4239..5261
                     /locus_tag="VXB18_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0382823.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPSGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5278..6147
                     /gene="licA"
                     /locus_tag="VXB18_001648"
     CDS             5278..6147
                     /gene="licA"
                     /locus_tag="VXB18_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0382824.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6137..7015
                     /locus_tag="VXB18_001649"
     CDS             6137..7015
                     /locus_tag="VXB18_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0382825.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVVNGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7027..7716
                     /locus_tag="VXB18_001650"
     CDS             7027..7716
                     /locus_tag="VXB18_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0382826.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7812..8660
                     /gene="dprA"
                     /locus_tag="VXB18_001651"
     CDS             7812..8660
                     /gene="dprA"
                     /locus_tag="VXB18_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0382827.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(8982..9062)
                     /locus_tag="VXB18_001652"
                     /pseudo
     CDS             complement(8982..9062)
                     /locus_tag="VXB18_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9634..10677
                     /locus_tag="VXB18_001653"
     CDS             9634..10677
                     /locus_tag="VXB18_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0382828.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            10844..12931
                     /gene="topA"
                     /locus_tag="VXB18_001654"
     CDS             10844..12931
                     /gene="topA"
                     /locus_tag="VXB18_001654"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0382829.1"
                     /translation="MATVTKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13152..13511
                     /locus_tag="VXB18_001655"
     CDS             13152..13511
                     /locus_tag="VXB18_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0382830.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13604..14236
                     /locus_tag="VXB18_001656"
     CDS             13604..14236
                     /locus_tag="VXB18_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0382831.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14280..14936
                     /locus_tag="VXB18_001657"
     CDS             14280..14936
                     /locus_tag="VXB18_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0382832.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14955..16049
                     /locus_tag="VXB18_001658"
     CDS             14955..16049
                     /locus_tag="VXB18_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0382833.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKKQEITDADT
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            16061..17098
                     /gene="leuB"
                     /locus_tag="VXB18_001659"
     CDS             16061..17098
                     /gene="leuB"
                     /locus_tag="VXB18_001659"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0382834.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            17095..17364
                     /locus_tag="VXB18_001660"
     CDS             17095..17364
                     /locus_tag="VXB18_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0382835.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17368..17727
                     /gene="leuD"
                     /locus_tag="VXB18_001661"
     CDS             17368..17727
                     /gene="leuD"
                     /locus_tag="VXB18_001661"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0382836.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17889..18512
                     /locus_tag="VXB18_001662"
                     /pseudo
     CDS             17889..18512
                     /locus_tag="VXB18_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         5824 a         3220 c         3930 g         5614 t
ORIGIN      
        1 tgggaatatg tatttcattt tctactaaaa ttatgttttt gaataacctc tatcttagta
       61 gtttgtataa tccccctcaa tcagtttttg cgataagctt taatgctatg actataccac
      121 tcttgcattt cttttgatgg tggtgtcata taatcgccat acatctgggt taaaaattgg
      181 tcatattttt tgggaacagg caacatacgg ccctcaaact cagttaaaat cagttcttta
      241 aaggtatcaa ctgggaagat ttctttcatc ccttccttac cgatcccaac tcctccttca
      301 tattgaggag tgttggttac agcatttttg actagttgat caattttctt gtaaaagtag
      361 cgaggattga caaatcggag agcgtaccag ctacataatc taagaaaatc ttttagtttg
      421 ctatcaccgt gaactgctcg tgattttttg atataagcta gttgacgaag agccacatac
      481 ttatagctct tgtcgacaat gatcaagtct gtaaatcgat caattgggaa gacatcgatg
      541 aaaaggctgg tatcatgacg cttgtactta acatggtctt ctataacagt agaagtgtcc
      601 aaaatcgatg cgaaattatg gaagtaccaa gaagatgtat cgtaggaaag aaccttgtag
      661 cgagggtgat tttcttcttc aataatcttc agtaaacgct cataatcctc acgataaagg
      721 gaaatatcaa tatcatcatc ccaaggaatc atacctttgt ggcggatggc tccaagcatg
      781 gttccataac tgagaaaata aggaatatca tatttcttac aagtctcatc aatatagtcc
      841 agcagggcta gttgaatttc tttaatttct tttttttcta aatattgcat cctaatcctc
      901 caatttataa gcgtgaaatt catgactgta gaagcgtttt tcttctggtg gtagggtcat
      961 ataatctcca taaaattgtg tcaaaatagt atcaaatttt tcaggtgcag gaaggcttaa
     1021 attctcaaag ggtaaatcga ttgttttatc aaaggtacca cttgggaaga cttccttttc
     1081 cttaaatttt gaaggaataa aagccatata ctgcccattt tcacgactat atttttgaat
     1141 ttctttctcg attttatttg caaaataacg aggagaaacc ggtcgaagga gcaaccaaaa
     1201 ggctgttcgt atccaatctt ttaaaaggct atccttatag acaatatttt tatgtttact
     1261 gaaagacagc agtttgaagc tttccagttt ataacaagta tcaatgacct taggatcatc
     1321 aaagcgatct atagggaaaa tatcgataaa gataccagac tcataggttt ttgtatttcg
     1381 agtatcaata attttagtcg tactgtcggt tatcttgata aagttgttaa agtagttctt
     1441 atcagtttct aaggatagga gcttatactt gcttttttcc ttttgaaaaa tgttaataaa
     1501 tcgttggtag tcttctctag gcatggataa atcaatatcg tcgtcccaag ggataaagcc
     1561 ctcatgtcga accgccccaa tcagagtacc gtagttaata atatagttga tattgtgctt
     1621 tttacagaga gtatcaatat aatccaaaat ttctaattca atttgtttgg catcttcaac
     1681 ggttagttgt ttcattttaa actcctatga ttttttaaat ttatttttta aggctaggac
     1741 atggtttaaa aattcataga aaatgctatc ttttgtgaag acaagtagac taatataaga
     1801 gatagctgat agcaagacaa tcaaaccagt attaatcaaa aatggcaaat taatgaccat
     1861 atctacagga tacacgaaat taatcaggaa ataaattgct acaaaggaaa gtgaaaagag
     1921 agagtatcga acagtatagc taaagatatg tcccaagtgg atgagttgtt ttctatggat
     1981 gaaaatgata tagaaaacaa gtagagaagt ctctgatagc atagttgtca gtaagtagta
     2041 ttcaggagcc acgatatggt tgaaaaaaag gagactattc aagcccaaat tgagtagccc
     2101 agcaaagact gtatagactg tgatacgttt ttcatagcca ttggtaaaga gaatttggga
     2161 accaagaatg gtatctaagg ccaggataat cgtacgaaaa gcgaagagag aggtcaagat
     2221 gccgcctccg atatattttt cactaccgta aagtaggatg gcatttggtc ctaaaaccat
     2281 gagtccaaaa ctcagtggaa tgataaagaa gttaaagatt cgactacctc tattaaccag
     2341 agaaacatag gcttctttgt ctcctttccc cagatagtaa ctgagacgag gcacactcac
     2401 tccaattgca cctgttacaa ccccagctat aacggtcaca attcgctgag ctatggtata
     2461 gtaactaacg ttgacatcaa tccctgtttt aacgaggaag aggcgatcta aaaaagtgaa
     2521 gagcatattg gcattggcaa agactaacat ggctgtcaga gggagaaaga gtggtttaaa
     2581 atcacttagg tgaattttaa caagtttgat gtctctttta atccaaaaat aactaatcag
     2641 gtagttaatc agcgtcgata aactcatcac aagtgtatag acaacaatat cgtgttcatt
     2701 tttaacaaat aagaaaatag agaccagcat caggatacgg atgaaggcag ttttgtaaaa
     2761 gagaaaactg taattttcca gagcttcatt gacccattcg attgaaaaaa tctgggcaat
     2821 gagttgaatc cccataacaa ggtagacctt tttgacgatt ggattatcag taaagaagag
     2881 aggataggct aggatataga cagcagtggt caaaatcgta caagcgatgc acaaataaaa
     2941 aagactagaa aaggttctgt taagatcttt tttgttatcc ttgacattac tgatagccct
     3001 taaaccgtag ctatagacac cataagttgc aaagggcaag aaaaatgaca aaatagtgtc
     3061 gactgagttg aagtaaccat agtcagttcg gtccaagaca cgcgcgacat aggttccagt
     3121 taggatggga aaaataatat tcaagacacg aattcccatg taagatagag catttaattt
     3181 tatacttttc attcaattta cctcgttttt cattatatca taaagttagc taataagaaa
     3241 tgaagggcag caagtcaaac aatcgctttg aagtttcaaa tcttaaatat taagttttct
     3301 ttaaggaaag tatattattc tgaaggactc taaaatttcg cagtcattta ttagtaattg
     3361 ctacagaatt cctagtcatt actagaaata ggcttgtttc tttgaataat agaactgcat
     3421 aattctccta ttctagaagg ggaggaccag tatttctttc atgataggac tagattgtgg
     3481 tataatagag agaataagtt ttttagtaag acaaaggaga aaatagatga tttatgcagg
     3541 aattcttgcc ggtggaactg gcacacgcat gggaatcagt aacttgccaa aacaattttt
     3601 agagctaggt gatcgaccta ttttgattca tacaattgaa aaatttgtct tggaaccaag
     3661 tattgaaaaa attgtagttg gggttcatgg agactgggtt ttacatgcag aagatcttgt
     3721 agataaatat cttcctcttc ataaggaacg tattatcatt acaaagggtg gtgctgaccg
     3781 caatacaagt attgagaaca tcattgaagc cattgatgct tatcgcccgc ttactccaga
     3841 ggatatcgtt gttacccacg attctgttcg tccatttatt acgcttcgca tgattcaaga
     3901 cagtatcaaa cttgctcaaa atcatgacgc agtggataca gtagtagaag cagtggatac
     3961 tatcgttgaa agtaccaatg gtcaattcat tacaggtatt ccaaatcgtg ctcacctcta
     4021 tcagggacaa acacctcaaa cattccgttg caaggacttc atggaccttt atggatctct
     4081 ttctgatgaa gagaaggaaa tcttgacaga tgcatgtaaa atctttgtga tcaaaggaaa
     4141 agatgtagcc ttggccaaag gcgaatactc aaatctgaag attacaaccg taacagattt
     4201 gaagattgca aaaagtatga ttgagaaaga ctagtaaaat gattaatcaa atttatcaac
     4261 taactaaacc taagtttatc aatgtcaaat atcaggaaga ggctattgac caagagaatc
     4321 atatccttat ccgtcccaac tacatggctg tctgtcatgc ggatcagcgt tactaccagg
     4381 gaaaacgtga tcccaagatt ttgaataaaa agcttccaat ggcaatgatt cacgagtcat
     4441 gtggaaccgt catttctgac ccgagcggaa cctacgaggt tggtcaaaaa gttgtcatga
     4501 ttcccaatca gtctcctatg cagagtgatg aagaattcta tgaaaactac atgacaggga
     4561 cccatttctt gtctagtgga tttgatggct ttatgagaga gtttgtttct ctccctaaag
     4621 atcgtgtggt ggcttatgat gctattgaag atacggttgc agccattaca gagtttgtca
     4681 gtgtgggcat gcacgctatg aatcgtctat tgactcttgc tcatagcaag cgggagcgga
     4741 tcgccgttat tggagatgga agtttagctt ttgtggttgc caatattatc aactatactt
     4801 tgccagaagc agagattgtg gttattggtc gtcattggga aaagttggaa ctcttctcat
     4861 ttgccaaaga atgctatatt acggataata ttcctgaaga gttggccttt gaccatgctt
     4921 ttgaatgttg tggtggtgat ggtactggac cagctattaa tgacttgatt cgctacattc
     4981 gtcctcaggg aacaattctc atgatgggag ttagcgaata taaagtcaat ctcaatactc
     5041 gcgatgcctt agaaaagggc ttgctcttgg ttgggtcatc tcgttctggt cgcattgatt
     5101 ttgaaaatgc tatccaaatg atgaaagtca agaaatttgc caatcgtctt aaaaatatcc
     5161 tttatctaga agaacctgta agagaaatta aagatattca ccgtgtcttt gcaaccgatt
     5221 taaacacagc ctttaaaaca gtgtttaagt gggaagtata agtcctggag gttaattgtg
     5281 gagaaaatca ttaaagaaaa aatttcttcc ttacttagtc aagaagaaga agtcctcagt
     5341 gttgaacaac tgggtggaat gaccaatcaa aactatttgg ccaaaacaac aaataagcaa
     5401 tacattgtta aattctttgg taaagggaca gaaaagctta tcaatcgaca agatgaaaag
     5461 tacaatcttg aactactaaa ggatttaggc ttagatgtaa aaaattatct ttttgatatt
     5521 gaagctggca tcaaagtaaa tgagtatatc gaatctgcga ttacgcttga ttcaacgtca
     5581 atcaagacca agttcgacaa aattgctcca atattacaaa ctattcatac atctgctaag
     5641 gaattaagag gagaatttgc tccttttgaa gaaatcaaaa aatacgaatc cttgattgaa
     5701 gaacaaattc cttatgccaa ctatgaatct gttagaaatg cagtcttctc cttagagaaa
     5761 agactggctg acttaggtgt tgacagaaaa tcttgtcata tcgatttggt gcctgaaaac
     5821 tttatcgaat cacctcaagg acgactttat ttgattgact gggaatattc atcaatgaat
     5881 gatccaatgt gggatttggc tgccctcttt ttagagtctg aattcacttc ccaagaggaa
     5941 gaaactttct tatctcacta tgagagtgac caaacaccgg tttctcatga aaagattgct
     6001 atttataaaa ttttacaaga tactatttgg agtctatgga ctgtctataa ggaagagcaa
     6061 ggtgcagatt ttggttacta tggtgtgaat cgttaccaaa gagctgttaa aggtttggct
     6121 tcttatggag gatcagatga aaagtaaaaa cggagttcct tttggccttc tctcaggtat
     6181 tttctggggc ttgggtctaa cggttagtgc ttatatcttt tcgattttta cagatttgtc
     6241 accctttgtg gtggctgcag ctcatgattt tttgagcatc tttatcttac tagcttttct
     6301 cttggtaaaa gaagggaaag ttcgcctctc aattttctta aatattcgca atgtcagtgt
     6361 tatcatcgga gccttgctag caggccctat cggtatgcag gccaatcttt atgcagttaa
     6421 gtatatcgga agttctttag cttcatctgt atcggctatt taccctgcga tttcagttct
     6481 attggctttc ttctttttga agcacaagat ttcgaaaaat actgtatttg ggattgtctt
     6541 gattattgga gggattattg cccagaccta taaggttgaa caggttaatt ccttctacat
     6601 tgggattctc tgtgctttgg tttgtgctat tgcatgggga agtgagagtg ttcttagctc
     6661 ctttgctatg gaaagtgaac tgagtgaaat cgaagccctc ttaatccgtc aagtgacttc
     6721 gttcttgtcc tatcttgtga ttgtgctctt ctctcatcag tcatttactg cagtagtcaa
     6781 tggacaattg ctaggtctca tgattgtttt tgcagccttt gatatgattt cctacttggc
     6841 ttattatatc gctatcaatc gcttgcaacc agccaaggct acaggcttga acgtgagcta
     6901 tgtagtatgg acggtcttgt ttgcagttgt ttttttgggt gcaccgctag atatgctgac
     6961 cattatgacg tcacttgtcg tcattgctgg agtttatatt attattaaag aataaaggag
     7021 attcgtgtga aagccattat cttagcagcg ggattgggaa ctcgcttgcg tcctatgact
     7081 gaaaataccc ctaaagcctt ggttcaggtt aatcaaaaac ctttgattga ataccaaatt
     7141 gagtttctca aagaaaaagg aatcaatgac atcatcatca ttgttggtta tcttaaagaa
     7201 caattcgatt acttaaaaga aaaatacggt gttcgcctcg ttttcaatga taaatacgct
     7261 gactacaata acttttactc tctctatctt gtaaaagaag aattggccaa cagctatgtt
     7321 attgatgcag ataactatct ctttaaaaat atgttccgca atgatttgac tcgttcgact
     7381 tattttagtg tttatcgtga agattgtacc aacgaatggt tcttggtcta tggagatgac
     7441 tacaaggttc aagacattat tgttgatagc aaggcaggtc gcatccttag tggtgtatcc
     7501 ttctgggatg ctccaactgc agaaaagatt gtcagcttta tcgacaaggc ttatgcaagt
     7561 ggcgaatttg ttgatctcta ctgggacaat atggttaagg ataatatcaa agagctagat
     7621 gtctatgttg aagaattaga aggcaatagc atttatgaga tcgatagtgt ccaagactat
     7681 cgtaaattag aagaaattct taaaaacgaa aattaaagat tccaacatct gacaaaatag
     7741 tcggatgttt tttgattttt tacgaacttt tacgaataga tagatgagta gaaaaagaaa
     7801 tggagttatt tatgaaaatc acaaactatg aaatctataa gttaaaaaaa tcaggtttga
     7861 ccaatcaaca gattttgaaa gtgctagaat acggtgaaaa tgttgatcag gagcttttgt
     7921 tgggtgatat tgcagatata tcaggttgtc gtaatccagc cgtttttatg gaacgttatt
     7981 ttcagataga cgatgcgcat ttgtcgaaag agtttcaaaa atttccatct ttctctattt
     8041 tagatgactg ttatccttgg gatttgagtg aaatatatga tgcgcctgta cttttatttt
     8101 acaagggaaa tcttgacctc ctgaaattcc cgaaggtagc ggtcgtgggc agtcgtgctt
     8161 gtagcaaaca gggagctaaa tcagttgaaa aagtcattca aggcttggaa aatgaactgg
     8221 ttattgtcag tggtctggcc aagggcattg acacagcagc tcatatggca gctcttcaga
     8281 atggcggaaa aaccattgca gtgattggaa caggactgga tgtgttttat cctaaagcca
     8341 ataaacgctt gcaagactac atcggcaatg accatctggt tttaagtgaa tatggacctg
     8401 gcgaacaacc tctgaaattt cattttcctg cccgtaatcg catcattgct ggactttgtc
     8461 gtggtgtgat tgtagcagag gctaagatgc gttcaggtag tctcattacg tgtgagcgag
     8521 caatggaaga aggacgcgat gtctttgcta ttcctggtag cattttagat ggactatcag
     8581 acggttgcca tcatttgatt caagaaggag caaaattggt caccagtggg caagatgttc
     8641 ttgcggaatt tgaattttaa aaatgaccta agctagaatt ctaagaaaaa atcaatttta
     8701 agagaaaatg aacccaacat ttccataata aaacgcatat tagcaagttt ttaacacttg
     8761 ataatatgcg ttttttctaa gtggattagt agagtagagg atttttctca tataatactc
     8821 ttcgaaaatc tcttcaaact acgtcagctt ccatctgcaa cctcaaaaca gtattttgag
     8881 ctgacttcgt cagtcttatc tgcaacctca aaacagtatt ttgagctgac ttcgtcagtc
     8941 ttatctgcaa cctcaaaaca gtattttgag ctgacttcgt cagtcttatc tacaacctca
     9001 aagcagtgct ttgagcaacc tgtggctagc ttcctagttt gcgctttgat tttcattgag
     9061 tataagggaa agtatagtga attgaaataa gatgtgaaca actctatcag gaaagtcaaa
     9121 ttaatttata gaaatatttt agcagccaag gtgcactgtt atagattcaa tacactataa
     9181 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
     9241 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
     9301 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
     9361 taaaaaatgg tctgaaatag atgatgatac ttttcgaaaa tctttttacg tcagctcagc
     9421 tttgccttgc tgtgttttga gcaagctacg gttagcttcc gagtttgatt ttcatttact
     9481 agaaatgaaa ctgatgagag atatcagtag acatttgagt caggatatta tggaaaatga
     9541 taaaaagagc tcgtgagatt ggcatatcag actactaaag tattgagttt gttaggattt
     9601 tagcgactag ttagctggga aaggaagata tttgtgacaa ataataaact gtattcgttg
     9661 atagaattta gaaataaaat atatgaagaa ttagaacttt ccagaagtga tttagcgatt
     9721 ttactatgtg ccatgcttat cgcctctatc ggattaaata tggattcgac tcccgtgatt
     9781 attggagcca tgttaatctc tcctttgatg acacctattc tgggagtggg gctctctcta
     9841 gctatatttg attttaaatt gttaagaaaa tcttttaaaa tattagctat tcaaattctt
     9901 gccagtctaa tagcttcaac actttatttt tatctttctc ccatttcgta tgctagttcg
     9961 gagattgttg ctagaacctc tccgactatt tgggatgttc tcattgcttt tgtaggaggg
    10021 atagcaggta ttattggtgc taggaaaaaa gagaccaata atattgttcc tggtgttgct
    10081 attgcaaccg ccttgatgcc tcctctttgt acagtaggtt atgctattgc ttctgctaat
    10141 ctaaaattta tcataggctc ctcttaccta tttctcatca attgtagctt tattgtcatt
    10201 gcgacttata taggtgttag gttgatgatg gttaagaaac attattttaa agataatgaa
    10261 gaagactcta aaatgcgtag gattttgctt ctagttgctg ttttgctgat gattccgagt
    10321 ttcatctctg caacgacttt agtgagagaa acgttgaaaa aagagtccct taagaaattt
    10381 atatcagagc agtttcaggg gcataatatt ttgaaaaaaa cctattctaa aaagactcat
    10441 accctaaagc taaccatttc aggaaattat ttgacagaag aagaactcga tatgatttca
    10501 agtaagagag gtgactatgg tttaagtgat gtttctgttc aagtttcaca attgtctgat
    10561 tcagaacaac ttagtaagga agaactggtg gagtatttct tccagtatat caaggataag
    10621 gaagcaaaag aaaaggaaaa agctaataag ttttatacag agtctgagga gcaataattt
    10681 cttgagaata gctggttttt ctcgtgagtc ttctatgtat atcaaaggaa gactgaggtt
    10741 ttaagtataa aacttttctt ctattatagt agctaagtct tgacagggtt caaaaaatgg
    10801 tttacacttt ataaagttta ttactttgaa aaggtgtgat actgtggcta cggtaacaaa
    10861 aaagaaaaaa tcaacagtta aaaaaaatct agtcatcgtg gagtcgcctg ctaaggccaa
    10921 gacgattgaa aaatatctag gcagaaacta caaggtttta gccagtgtcg ggcatatccg
    10981 tgatttgaag aaatccagta tgtccgtcga tattgaaaat aattatgaac cgcaatatat
    11041 caatatccga ggaaaaggcc ctcttatcaa tgacttgaaa aaagaagcta aaaaagctaa
    11101 taaagttttt ctcgcgagtg acccggaccg tgaaggagaa gcgatttctt ggcatttggc
    11161 ccatattctc aacttggatg aaaatgatgc caaccgtgtg gtcttcaatg aaatcaccaa
    11221 ggatgcagtc aaaaatgctt ttaaagaacc tcgtaagatc gatatggact tggtcgatgc
    11281 ccaacaagct cgtcggatct tggatcgctt ggtagggtat tcgatttcgc ctattttgtg
    11341 gaagaaggtc aagaagggct tgtcagcagg tcgcgttcag tccattgccc ttaaactcat
    11401 cattgaccgt gaaaatgaaa tcaatgcctt ccagccagaa gaatactgga cagttgatgc
    11461 tgtctttaaa aagggaacca aacaatttca tgcttccttc tatggagtag atggtaaaaa
    11521 gatgaaactg accagcaatg acgaagtcaa ggaagtcttg tctcgtctga ctagtaaaga
    11581 cttttcagta gatcaggtgg ataagaaaga gcgcaagcgc aatgctcctt taccctatac
    11641 cacttcatct atgcagatgg atgctgccaa taaaatcaat ttccgtactc gaaaaaccat
    11701 gatggttgcc caacagctct atgaaggaat taatatcggt tctggtgttc aaggtttgat
    11761 tacctatatg cgtaccgatt cgactcgtat cagtcctgta gcgcaaaatg aggcggcaag
    11821 cttcattacg gatcgttttg gtagtaagta ttctaagcac ggtagcaagg tcaaaaacgc
    11881 atcaggtgct caggatgccc atgaggctat tcgtccgtca agtgtcttta atacaccaga
    11941 aagcatcgct aagtatctgg acaaggatca gctcaagcta tataccctta tctggaatcg
    12001 ttttgtggct agccagatga cagcggccgt ttttgatacc atggctgtta aattgtctca
    12061 aaaaggggtt caatttgctg ccaatggtag tcaggttaag tttgatggtt atcttgccat
    12121 ttataatgat tctgacaaga ataagatgtt accggacatg gttgttggag atgtggtcaa
    12181 acaggtcaat agcaaaccag agcaacattt cacccaaccg cctgcccgtt attctgaagc
    12241 aacactgatt aaaaccttag aggaaaatgg ggttggacgt ccatcaacct acgcgccaac
    12301 cattgaaacc attcagaaac gttattatgt tcgcctggca gccaaacgtt ttgaaccgac
    12361 agagttggga gaaattgtca ataagctcat cgttgaatat ttcccagata tcgtaaacgt
    12421 gaccttcaca gctgaaatgg aaggtaaact ggatgatgtc gaagttggaa aagagcagtg
    12481 gcgacgggtc attgatgcct tttacaaacc attctctaaa gaagttgcta aggctgaaga
    12541 agaaatggaa aaaatccaga ttaaggatga accagctgga tttgactgtg aagtgtgtgg
    12601 cagtccaatg gtcattaaac ttggtcgttt tggtaaattc tacgcttgta gcaatttccc
    12661 agattgccgt catacccaag caatcgtgaa agagattggt gttgagtgtc caagctgtca
    12721 tcagggacaa attattgagc gaaaaaccaa gcgtaatcgc ctattctatg gttgcaatcg
    12781 ctatccagaa tgtgaattta cctcttggga caagcctgtt ggtcgtgact gtccaaaatg
    12841 tggcaacttc ctcatggaga aaaaagtccg tggtggtggc aagcaggttg tttgtagcaa
    12901 aggcgactac gaggaagaaa agattaaata agaggagggg cccgaaagta aatttcaggc
    12961 tccttttggt tagaacttga caaaatacat cattttatgc gaaactagaa gaagattatt
    13021 ttatactcaa tgagaatcaa agagcaaatt agaaagctag tcgcaggttg ctcaaagcac
    13081 tactttgagg ttgaagatgg aagctgacct ggtttgaaga gattttcgaa gagtattaac
    13141 taggagaagt tatgcgtctt atctatctaa ttattggttt tttatcgctg gccttggcta
    13201 ttgttggggt tgttttaccc ttgttaccta caacaccttt ccttttgttg tctattgctt
    13261 gtttctccag aagttccaag cgattcgaag actggcttta tcataccaag ctctatcaaa
    13321 catatgtagc tgattttcgc gagactaagt ctattacgcg tgaacgaaag aaaaaaatca
    13381 tcgtctctat ctacgtcttg atgggaattt ctatttattt tgcacctctt ttaccagtca
    13441 aaatcggtct gggtgctttg accatcttta tcacttatta tcttttcaag gtcattccag
    13501 acaaagaata gttaaaacag tagttatttg ccttgataaa attgaaagca tattcataac
    13561 aatatgatat aataaatttg aagtaatatt caaggagaat caaatgattt acgaattttg
    13621 tgctgaaaat gtgactttac ttgaaaaagc gatgcaggct ggagctcgtc ggattgaact
    13681 ctgtgataat ctagcagttg gtgggacaac acccagctat ggagtgacta aggcagcggt
    13741 tgaactggca gctaactacg atacaaccat catgaccatg attcggccac gtggtggtga
    13801 ctttgtctat aatgacctag aaattgctat catgctagaa gacatttgtt tgactgctca
    13861 ggctggaagt caaggggttg tatttggagc tttaactgct gataaaaagt tggataagcc
    13921 taatctggaa aagttaattg ctgcatcaaa aggaatggaa attgtctttc acatggcctt
    13981 tgatgaacta agtgatgaag atcaaccgga agctattgac tggctcagtc aagccggtgt
    14041 cactcgtatc ctaactcgtg ctggtgtgtc tggcgactcc ttagaaaaac gttttgttca
    14101 ctatcacaga attttggagt acgctaaagg taaaattgaa attctaccag gtggggggat
    14161 tgaccttgac aaccgtcaaa cctttattga ccaggtgggg gtaacacaat tgcatggtac
    14221 taaggttgtt ttttaaaaaa tagaaaggaa ctgctagcct tgggtagcag ttttcactta
    14281 tgtttgaaat ttttaaatcc tatcaattta atcaagaaaa ggctcatgat tatggtttta
    14341 tagaaaatag cgaagtctgg acatatagtt gccagatttt gcaaggtgac tttgtcatga
    14401 ctgtgtccat cactgctgat aatgtgaact ttcaagtctt tgaccaagag actggtgacc
    14461 tctatcctca cgttcatatg gaaagcatga ggggaagttt tgtcggaaat gtccgtgagg
    14521 cttgtctgga gattctttac cagattcgga aggcttgttt tgatgtgcaa gattttatct
    14581 gtcatcagac taagcgtatc atgactcaag ttcaggaaaa gtatggaaac cagttggagt
    14641 atctgtggga aaaatcgcct gatacagctg tattgcgcca tgaaggcaat caaaagtggt
    14701 atgccgtctt gatgaaaatc tcttggaata agctggaaaa gggcagagaa ggacaagtgg
    14761 aagcagtcaa cctcaagcat gaccaagtag ctaatttgct ttcacaaaag gggatttatc
    14821 cagccttcca tatgagcaag cgctactgga ttagtgtgtc ccttgatgat actttatcag
    14881 atgaagaagt actggaattg atagaaaaaa gttggaactt aacctctaaa aaatgaaata
    14941 ttttaataat tttcatgaac tttcaattag ctaaatattc tttactaaag aaattttcag
    15001 aaaatatagg atttaccaca ccagaggaat atggtgccat cttcaaatac ctgattgaga
    15061 atgtcaagac ggatcgtcag atcatctatt cgcctcactg tcatgatgac ctcggaatag
    15121 cagtggcaaa tagccttgct gctgtcaaga atggtgcagg acgtgttgaa gggactatca
    15181 atggtattag ggagcgagct ggaaatgctg ctttggaaga aattgcagtg gctctcaata
    15241 ttcgccaaga ttactaccaa gtagaaacca gtattgtcct aaatgagacc atcaatacgt
    15301 cagaaatggt ttctcgcttc tctggtattc cagttcctaa aaacaaagcc gtcgttggtg
    15361 gcaatacctt ctcccacgaa tctggtattc accaagatgg agtccttaaa aatcctctca
    15421 cttatgagat catcacacct gaattggttg gtgttaagat tccgcttgga aaattatctg
    15481 gtcgccatgc ttttgttgag aaactgagag aattggccct agattttaca gaagaggata
    15541 tcaaaccact ctttgctaag ttcaaggcac tggccgataa gaagcaagaa atcacagatg
    15601 cagatactcg agctttggta gctggaacca tggttgaaaa tccagaaggc ttccactttg
    15661 atgatttaca acttcaaact catgcagata atgacattga agcgctcgtt agcctagcca
    15721 atatggatgg tgagaaagtc gaatttaatg cgacagggca aggttccgtt gaagcaatct
    15781 ttaacgctat cgataagttc tttaaccaat ctgttcgttt ggtgtcctac actatcaatg
    15841 cggtaacaga tggaatcgat gcccaggatc gggttttggt cactgttgaa aacagagata
    15901 cagaaaccat ctttaatgca gcagggcttg attttgatgt gttgaaggct tctgctattg
    15961 cctatataaa cgctaatacc tttgttcaaa aagagaatgc aggtgagatg ggacgcagtg
    16021 tttcttacca cgatatgcct agtgtgtaaa ggagaaggct atggcaaaga aaatagtagc
    16081 tctagtagga gacggaattg gcccagaaat catggaggct ggtttagaag ttctggaggc
    16141 tctagctgaa aaaacaggtt ttgactatga gattgacaga cgaccgttcg gaggtgcaga
    16201 tattgatgca gcaggacctc ccttacctga tgaaaccctt aaggcaagta gggaagcaga
    16261 tgctatccta ctagcagcta tcggtagtcc tcagtatgat ggagcagcgg ttcgccctga
    16321 acaaggcctg atggctctcc gtaaggaact caatctttac gctaatattc gtcctgtaaa
    16381 aatctttgac agtctcaagt atttgtcacc actcaaaccg gaacgaattt ctggtgtaga
    16441 ctttgtcgtg gtgcgtgaat tgacaggcga gatttacttt ggagatcata ttcttgaaga
    16501 gcgcaaagcg cgtgatatca acgactatag ctatgaggaa gtggagcgga ttattcgcaa
    16561 agcctttgaa attgcaagaa atcgcagaaa aatcgttact agtatcgata agcaaaatgt
    16621 tctagcgacc tcaaaactct ggcggaaagt agctgaggaa gtcgcacagg atttcccaga
    16681 tgtaaccttg gaacaccagc tggtagactc agctgctatg cttatgatta ccaatcctgc
    16741 taagtttgat gttattgtaa cggagaatct ttttggagat attttatctg atgaatcaag
    16801 cgtcttatct ggtacacttg aggttatgcc atcagccagt cattctgaaa atggaccaag
    16861 tctctatgaa cctattcacg gttcagcacc tgatattgca ggtcaaggaa ttgccaatcc
    16921 tacttccatg attttatcag ttgccatgat gttgagagat agtttcggac gttatgagga
    16981 tgcagagcgt atcaaacgtg ctgttgagac aagtctggcg gcaggaattt taacgagaga
    17041 tataggaggt caggcttcaa caaaggaaat gacggaagct attattgcaa ggttatgaag
    17101 ttagacgaaa aaattactct agtccttttg atttggaatg tcatcatttt cttgatttat
    17161 ggcattgaca aattcaaggc aagaagaaga acttggcgca tccaagagaa aatcttactc
    17221 attttagccc ttacttgtgg tggttttggg gcctggttag ctggaatcac ttttcaccac
    17281 aagactcgaa aatggtactt taaaacagtt tggtttcttg ggatggtgac cacactagta
    17341 gccttatatt ttatttggag gtaatggatg gcagggtctt cgagggaaca cgctgcttgg
    17401 gctctagcgg actatggttt taaggtcgtg attgcaggat ctttcggtga cattcattac
    17461 aataatgaac tcaataatgg catgttgcca atcgttcagc ctagagaggt tagagagaaa
    17521 ctagcccagc taaaaccaac cgaccaggta actgtggact tggaacaaca aaaaatcatc
    17581 tcaccagttg aagaattcac cttcgagata gatagcaagt ggaaacataa actcctaaat
    17641 agtttggatg atatcggtat taccttgcag tatgaagagt tgattgctgc ttatgaaaaa
    17701 caacgaccag cctactggca ggattagaaa aaatagaaaa ggaaatatag taaactgaaa
    17761 taagatgtaa acaaatgaat tggagcttaa catccatttc cagcaatttt ttagaaacta
    17821 cagtggacta ttctggattc aacacattat aaaattatga caaaacacat tcacaagaag
    17881 gctacgacat tttaaaaggt gagggcggat gtatcgtttg ccctactaaa gttggttaca
    17941 ttatcatgac cagcaacaag gcaggacttg agcgtaagtt cgcagccaaa gaacgtaagc
    18001 gtaacaaacc aggtgttgtt ctctgcggta gcatggatga acttcgcgct ttagcgcaac
    18061 tcaacccaga aattgaagca ttctactaaa aacattggat gaagatattc ttcttggttg
    18121 tatccttcct tggaaaccag aagcctttga aaaactcaaa gcatacgggg atggccgtga
    18181 agaacttatg actgatgtac gtggtactag ctgttttgtt atcaagtttg gaaaagcagg
    18241 tgaacaattg gctgccaagc tttgggaaga aggtaaaatg gtctacgcct catatgcttc
    18301 aatgacaaaa cgattgaaac tcgctatgag agcaaggtgt aatggtgtct atggtcgata
    18361 aggacggcaa actcatccca gaacaaggag gagcacgttc aacttcacca gcaccagttg
    18421 tgatccgtaa agggcttgac attgataaaa tcatgatgca cctgtcagat acttttaact
    18481 catgggacta ccgtcaggtt gagtattatt aagataaaaa aagaagtcta gtgttatgag
    18541 atattaaagc tcctaacact ggactttttg tttagaattt cttttctt
//
LOCUS       DAVKZI010000040        17134 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKZI010000040 DAVKZI010000000
VERSION     DAVKZI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.041"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..265)
                     /locus_tag="VXB18_001663"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VXB18_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            390..848
                     /locus_tag="VXB18_001664"
     CDS             390..848
                     /locus_tag="VXB18_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0382837.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            861..1469
                     /locus_tag="VXB18_001665"
     CDS             861..1469
                     /locus_tag="VXB18_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382838.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSRLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1540..1872
                     /locus_tag="VXB18_001666"
     CDS             1540..1872
                     /locus_tag="VXB18_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382839.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1883..3298
                     /gene="ply"
                     /locus_tag="VXB18_001667"
     CDS             1883..3298
                     /gene="ply"
                     /locus_tag="VXB18_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0382840.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4179..4895
                     /locus_tag="VXB18_001668"
     CDS             4179..4895
                     /locus_tag="VXB18_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0382841.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5019..5468
                     /locus_tag="VXB18_001669"
     CDS             5019..5468
                     /locus_tag="VXB18_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0382842.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNCLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            5507..6328
                     /locus_tag="VXB18_001670"
     CDS             5507..6328
                     /locus_tag="VXB18_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0382843.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            6335..7366
                     /locus_tag="VXB18_001671"
     CDS             6335..7366
                     /locus_tag="VXB18_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0382844.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSIIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7431..7793
                     /locus_tag="VXB18_001672"
     CDS             7431..7793
                     /locus_tag="VXB18_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV0382845.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGEKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERITITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7790..8293
                     /locus_tag="VXB18_001673"
     CDS             7790..8293
                     /locus_tag="VXB18_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0382846.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSAGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8407..8853
                     /locus_tag="VXB18_001674"
     CDS             8407..8853
                     /locus_tag="VXB18_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0382847.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8858..9532
                     /locus_tag="VXB18_001675"
     CDS             8858..9532
                     /locus_tag="VXB18_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382848.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            9788..9976
                     /locus_tag="VXB18_001676"
                     /pseudo
     CDS             9788..9976
                     /locus_tag="VXB18_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            10226..10525
                     /locus_tag="VXB18_001677"
     CDS             10226..10525
                     /locus_tag="VXB18_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0382849.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10522..10839
                     /locus_tag="VXB18_001678"
     CDS             10522..10839
                     /locus_tag="VXB18_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0382850.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            10855..11481
                     /locus_tag="VXB18_001679"
     CDS             10855..11481
                     /locus_tag="VXB18_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0382851.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11514..12275
                     /locus_tag="VXB18_001680"
     CDS             11514..12275
                     /locus_tag="VXB18_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0382852.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADIVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12353..12748
                     /locus_tag="VXB18_001681"
     CDS             12353..12748
                     /locus_tag="VXB18_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0382853.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12904..13188
                     /gene="groES"
                     /locus_tag="VXB18_001682"
     CDS             12904..13188
                     /gene="groES"
                     /locus_tag="VXB18_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0382854.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13204..14826
                     /gene="groL"
                     /locus_tag="VXB18_001683"
     CDS             13204..14826
                     /gene="groL"
                     /locus_tag="VXB18_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0382855.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            14964..15719
                     /locus_tag="VXB18_001684"
                     /pseudo
     CDS             14964..15719
                     /locus_tag="VXB18_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            16165..16938
                     /locus_tag="VXB18_001685"
     CDS             16165..16938
                     /locus_tag="VXB18_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0382856.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            16951..>17134
                     /locus_tag="VXB18_001686"
     CDS             16951..>17134
                     /locus_tag="VXB18_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0382857.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENF"
BASE COUNT         5207 a         3014 c         3878 g         5035 t
ORIGIN      
        1 tctctcctta gatagcgcat ggttataggc tttatcttca actgttagcg gcttgagttt
       61 gctggattta cgtggagttt gtgcttgagg atatatcttc atgagccctt gataaccact
      121 gtcagccaag attttaccag cttgtccgac ttttttgata agctgttttt aatacagcta
      181 acatctcttc aaaagtggta cgctgaacac taacaagacg cttaaatcgt gcatcagtta
      241 gttgtttact tgcttcataa ttcatagaac tactatacca tattttgttt cgcaggaagt
      301 ctaataagtt atagtccagt ttttactata ctttgatatt caaatatgtt atactatggt
      361 tatcaaagta aatgaaagga gttacgaata tgacgccaga agaaatgtac ctgacagagc
      421 gattagacgt acagatagct cattttttaa agaaaagcgt tcaacatcgt agacgctata
      481 aggtattaaa aataacagaa atcgtggcag gtttcctcat agctgtcttt tgtgctattc
      541 ctatgccagg tgatcgctac cgtttgattt cggttgcctt atccagtctc ggcttgctgt
      601 gtgaggggat tatcaatttg tataatgcaa aggaaaattg gatttcttac caaaaaactg
      661 cgcaactcct ggagaaagaa aaattcctct atcaatgcca aacggagaaa tatgcaggaa
      721 agaccaaggc ttttgcccta tttgtcaaga catgcgaagg tcttatctca gaggagatta
      781 accagtggga aagtatccag tcaaaagaag tggcagctag tgcagatgct ccagttaaaa
      841 aagagtagga ggtagaggaa atgtctcaat ccagctacct gtcgcccttg ctctggttaa
      901 aaaaagaagc cgataaggaa aagatgagcg cgacccagtg ccagatattt ttcttttact
      961 atcaaatgtt tgagctctta tttgctagag aaagcgacat gaaagactta tgtctgggaa
     1021 cgaaaggttt ttatttctcg cagttagaga aaaatttgct ttctggagtt tcccgatttc
     1081 taaaaaactt ggaggggaaa gtaactctca aggctaacca agaagtatca gctcgcaaag
     1141 ccctttttct agccttgaca actagccaat cagattggca ggagttagct cctgtttttg
     1201 atttttatca gactatcggg aggcttgaaa atccttctcg cttgagttct caggacagac
     1261 aacatctgat gtggatttac cagtcagctt tggagaagga ttatattgtc aaggttattg
     1321 gcgacaagca ttttgtattg aagagacaag atgctactaa attgacagcg cgccaaactc
     1381 aaactttgga aattctgagt caatcagaag acttggtcaa tcctgtctat gttacattag
     1441 gagaaaaggg ggtgctcttg cttgattaag agaggagatg ttgtagctct ttatttgcct
     1501 tttccgacta ttagtagcga tttggctgtg aagaatcata tgtatatctg tattgacaac
     1561 agcatgacta aaaacaaaga gttggttaaa aatcagacct tcaaaccagc tctcttgacc
     1621 agacgtttgg tcaagaactt tatgatagaa gagccggatc tagctcgtaa tccttttaca
     1681 agaccaacct tgattgactt agataaggta tttatgttgg ataatacggt tattccgact
     1741 tcttatctag ccagacggcg acgcaatgtc tcagaagaat tgtacgagga aattttggat
     1801 tacttagtcc aaccacggct gatttcgctg aacaagtctg agtttatgca actcaatcca
     1861 ggaacttatt aggaggtaga agatggcaaa taaagcagta aatgacttta tactagctat
     1921 gaattacgat aaaaagaaac tcttgaccca tcagggagaa agtattgaaa atcgtttcat
     1981 caaagagggt aatcagctac ccgatgagtt tgttgttatc gaaagaaaga agcggagctt
     2041 gtcgacaaat acaagtgata tttctgtaac agctaccaac gacagtcgcc tctatcctgg
     2101 agcacttctc gtagtggatg agaccttgtt agagaataat cccactcttc ttgcggtcga
     2161 tcgtgctccg atgacttata gtattgattt gcctggtttg gcaagtagcg atagctttct
     2221 ccaagtggaa gaccccagca attcaagtgt tcgcggagcg gtaaacgatt tgttggctaa
     2281 gtggcatcaa gattatggtc aggtcaataa tgtcccagct agaatgcagt atgaaaaaat
     2341 cacggctcac agcatggaac aactcaaggt caagtttggt tctgactttg aaaagacagg
     2401 gaattctctt gatattgatt ttaactctgt ccattcaggc gaaaagcaga ttcagattgt
     2461 taattttaag cagatttatt atacagtcag cgtagatgct gttaaaaatc caggagatgt
     2521 gtttcaagat actgtaacgg tagaggattt aaaacagaga ggaatttctg cagagcgtcc
     2581 tttggtctat atttcgagtg ttgcttatgg gcgccaagtc tatctcaagt tggaaaccac
     2641 gagtaagagt gatgaagtag aggctgcttt tgaagctttg ataaaaggag tcaaggtagc
     2701 tcctcagaca gagtggaagc agattttgga caatacagaa gtgaaggcgg ttattttagg
     2761 gggcgaccca agttcgggtg cccgagttgt aacaggcaag gtggatatgg tagaggactt
     2821 gattcaagaa ggcagtcgct ttacagcaga tcatccaggc ttgccgattt cctatacaac
     2881 ttctttttta cgtgacaatg tagttgcgac ctttcaaaat agtacagact atgttgagac
     2941 taaggttaca gcttacagaa acggagattt actgctggat catagtggtg cctatgttgc
     3001 ccaatattat attacttgga atgaattatc ctatgatcat caaggtaagg aagtcttgac
     3061 tcctaaggct tgggacagaa atgggcagga tttaacggct cactttacca ctagtattcc
     3121 tttaaaaggg aatgttcgta atctctctgt caaaattaga gagtgtactg ggcttgcctg
     3181 ggaatggtgg cgtacggttt atgaaaaaac cgatttgcca ctagtgcgta agcggacgat
     3241 ttctatttgg ggaacaactc tctatcctca ggtagaagat aaggtagaaa atgactagga
     3301 gaagagaatg cttgcgacaa aaagaggcga tgatctctct gcggatatct gaaagtttat
     3361 ctcttgccta gcgatttcca ttggagtatg ctcgtgatgt taaaatgagt ctatcaaaca
     3421 ggatgtgtaa aaaagtaaaa agggtagcca attccttgat atacagggga ttgattatcc
     3481 tttacttgtt ttagatgatt ggaaattcaa gaatgacacg tatcggaaat attttgctgt
     3541 ttatatctaa tacccattta tggaaaaaat gaaattaaat atgaacaaat caattgctag
     3601 caatggttta gaagtgccag tgtactagtc taacttctcc atcttgggaa cacgtaaatt
     3661 atactcttcg aaaatctctt caaaccaggt cagccctatc cgcaacttca aaacagtgtt
     3721 ttgagcactc tgcggctagc tttctggttt gttctttgat ttttattgag tattagaggt
     3781 ttgcttagaa actcttctat tgatttctta gaatacaata gcgcctataa gaactgttgg
     3841 atttcaaagt atttacttga actatgatat gtctggagta gactgtcaac aaaaggtgca
     3901 gtatgattgt ttttgtcgct tatatctaca aacttcaaac agtaatttga gctgactttg
     3961 tcaaacttgg ctgaaacttt ctatttgcag ataatggtct agtttgtttt ttgaatgtgg
     4021 atgagtgtct gttgataaag atagaaaggc aagaccgtct tagcaggtaa agtgctatcc
     4081 tagcttgatt tgctaataaa atccatttcc tctagtgaaa atcaaaaaaa cttgtgttat
     4141 aataagaaag attaaaatgt gaaaaaagga gattcctaat gggacgtaaa tgggccaata
     4201 tcgtagctaa gaaaacggct aaagatggag ccaactctaa agtatatgca aaatttggtg
     4261 tagaaatcta tgtagcagct aaaaaaggtg atccagatcc agaatcaaac tcagctttga
     4321 aattcgttat cgaccgtgct aaacaagccc aagtgccaaa acacattatc gataaagcga
     4381 ttgataaagc caaaggaaac acagacgaaa cctttacaga aggacgttac gaaggttttg
     4441 ggccaaatgg ctctatgcta attgtggata ctttgacttc taacgtcaac cgtacagcag
     4501 ccaatgtccg tgcagccttt ggtaaaaacg gcggaaacat gggcgcttca ggttctgttt
     4561 cttacctttt tgacaacaaa ggtgttattg tatttggagg tgaagatgcg gacgcagtct
     4621 ttgagcaatt gctcgaagcg gatgtggatg tggatgacgt agaagcacaa gaaggtacaa
     4681 tcacagttta cacagcgcca actgaccttc acaaggctat cgttgctctc cgtgagtctg
     4741 gtattgaaga attccaagtg actgaattgg aaatgattcc tcagtcagaa gtggaattgt
     4801 caggcgaaga ccttgaaacc tttgaaaaac tttacagcgt tcttgaagac gacgaagacg
     4861 tccaaaagat ttatacgaac gtagatgggt tttaatttaa cctatagaac atgatcctaa
     4921 gtgagaaaat cacttgggat ttttttaatc aagaaaatag ttctcataga aatttaatta
     4981 ttctccagag aactattttt atttagaagg gggagattat gggtaaaccg atgttagtct
     5041 ttaagcgttt tggtcatcaa attcacctga tggtgcaaaa ggaagccaaa cgttgcggca
     5101 ttgaatttat gggtgggccg caaggtcagg ttgtgcattt tttggataat cgcgagaaaa
     5161 accaagactt ggtcttgatt aaagatatcg atcaggaact caatattacc aagtctgttg
     5221 ctagtaatct ggttaagcgt atagtgcaaa attgtttggt ggaattggag gcgagtcctg
     5281 ttgataagcg ggctaagttt gttcgtctga cggacaaagc acgttctcag atgcaacagg
     5341 ttaaggcttt ttttgaacgc atagacaagc agttgatgga agatattgat gaagatgaat
     5401 tactgatttt tgagaaggtt ctcggtcaac tacaggcaaa atatcaaggg aataggagga
     5461 gagaataaag aaattagcca aaagaattag tagaaaagaa tgggggatga ttttactagc
     5521 cattctcttt acttgctttt cggtctatct agagttggaa gtgccgacct atatctcgaa
     5581 aattacggat ttgctaggta gtcaagaaac taatttagat gagttgtggc agccggcaag
     5641 catgatgatg ggaatgtcct ttcttgcctt cttgtccgta gttgcagttg gattttttgc
     5701 atcccgagtg gcggcttctt atactagtag gctgagaagt gatattttta accgagtttt
     5761 ggattactcg cagacagaga ttaagaaatt ttcaattcct agcctcttga cgcgtactac
     5821 caatgacatt actcaagttc aaatgttgat tactatgggc ttgcaagtgg taacgcgtgg
     5881 ttcaattatg gctatctggg ctattgggaa gattttaggt cattcagaat actggctctg
     5941 ggccgtactt gtggtagtga ttgtcaacgt cctgatgacg accgttttga tgacgctagc
     6001 ctttccaaaa cagtccttga ttcaggggtt gacagataaa ctgaacagta tcactcgtga
     6061 gagtttaaca ggtattcgtg tcgttcgtgc ctacaatgca gaggattatc aaaatgaaaa
     6121 atttgcagca gtaaatgatg aattgacccg tttgaatttg tttgtcaacc gtcttatggc
     6181 tattttgaat cctatcatga tggggatttc aagtggtttg agtgtagcga tttactggat
     6241 tggggcctat gtgattaacg acgctgctcc gatagcgcgt ctgcctctct ttagtgacat
     6301 gattgttttc atgtcttatg ccatgtaggt tgtcatggac ttccttctca tgggagcact
     6361 cttcatcgtt cttccccgaa ctatggtctc tgctaagcgg attaatcaag ttttagattt
     6421 gcattcttct atccaaaacc ctgctcaagt gcagctgact gatgaaaact tcaaaggtca
     6481 ggtcgagttt aaggatgtga ccttccgcta tgcggcaaat tcggaggcag ttattgaaca
     6541 tgttagcttt aaagcagaaa ctggtcaaac agtggccttt attgggtcaa taggttctgg
     6601 taaatcaact ctggtcaatc tgattccacg tttctacgac gtgtcagcag gagaaattct
     6661 ggtggacggt gtcaatgttc aagactatga cttctctgcg acagctcatg ctggtcaaag
     6721 ggttgccatt gttgggccga ctggggctgg taagacaacc attgtcaatc ttttgatgaa
     6781 attctatgag attgataagg gaagtattcg cattgatggt gtggatacca aggctatgac
     6841 gcgttcagaa gtgcatgatg ccttttcaat ggtcttgcag gatacctggc tctttgaagg
     6901 aactattcga gacaatctca tctataatca aatagggatt agtgatgaac gaatgatgga
     6961 agctagtaag gctgtgggaa ttcaccactt tattatgacc ttgccagatg gctatgatac
     7021 catcttggat gacaccgtga ccttgtctgt aggacaaaaa caactattga ctattgcttg
     7081 tgcccttctt aaggatgcat cgcttttgat tttggatgag gcgacttctt ctgttgacac
     7141 acggacagag gaattgatcc aaaaagccat ggaccgtttg atggaaggac gcacatcctt
     7201 tgtcattgcc caccgcttgt caatcatccg aaatgcagac ttgatcttgg tcatgaaaga
     7261 tggaaatatc atcgagcaag gcaactatga ggaactgatg gcgcaaggtg gcttctacgc
     7321 tgacttgtac aatagtcaat ttacagaaga tgaagcagaa gaataaatca aaaaaggctt
     7381 gacggccttc tttttcttat ttatactagt acacatagaa agagagaagt atgagtcaga
     7441 aattatacaa tatgaaattt gctgctgtct acttagcctt gattgcaaaa gttgagcgaa
     7501 agggtgaaaa ggcagagtca gttcaccaag tgaccagttg gttgacaggg tatgaagtga
     7561 gtgacgttct tgcttgtctg gatagggatg ttacttacgg agattttttt ctacaagcac
     7621 catattatgt ccctgaacga attacaatta cagggaagat ttgcggtgtc cgtattgagg
     7681 aaattgatga tcctctgatg caggaaatac gtcgcttgga caagctagtg gattggcttg
     7741 ccaaggggaa aacatctcaa caagttctag aaaagtatga gaagcataaa tgaaaaatta
     7801 tcaagaatgg tatcgaaata tcagctccag actaactagt cgtccaattc ttttattcct
     7861 attacgcagt ttcaatcgtt tgatgacagt cgccatgccc ctggtctatc tgatcttgct
     7921 agtcaccact tacctgcaac taggacttgg tcagcaagtt ggggtttatg tgcttattcc
     7981 tgcatcaggt tttgtggcct tgtccctgtt tcgtaagaaa atcaatcacc cgagacctta
     8041 tgaaacttgg gatatctgtc cccttcttga taaggatagt gcgggacggt cgatgcccag
     8101 tcgccatgtc ttttctgcaa ctatcatctc catggcctgt ctgcatgcta gtctacctat
     8161 tggcttagta tgcttgatct tttcagcttt gctggggttg gtgagggttt tagggggtgt
     8221 tcattatccc aaggatgtct tggttggcta tgcttgtggt ctggtgtggg gattcctttt
     8281 cttcctattc tgacatgtaa gttaagctag tcctacaacc acttactgct tcaaattgac
     8341 cacttgcttt tttgcccttg tattcctaac ttagctttga tatagtagag tcagaaagga
     8401 gatgtgatga agttacgaat tgagattgac ggcaatttag aggagactga aattgtcatc
     8461 aagaccccca ctttgacaga tgaaattgca gacttgcaac ggctcttgca agagtcaaag
     8521 gctccgaggt tgacttttta caaggggaca ggtgaatatt atctagacct gtcagaaatt
     8581 ctcttctttg aaacagaagg gagcaagatc tacgctcata accagaagga agcttatgag
     8641 gttcgcctca agctctatga gttggagtct atcttgcctc gctattttaa tcgagtttcc
     8701 aagtcaacga tcgcaaacat ccgtcagatt tactcagtgg acaagtcctt ttcaggaacg
     8761 ggcaccattt ccttttatca gacgcacaag gaggttcatg tctcacggca ttaccaatcc
     8821 ctcctaaaag aaaatctaag aaacatgagg taataagatg aaaaagaaag catttggtat
     8881 tgtgttactt gtactagcag ctttaatatt agtacaagga aattttggaa tcccttctct
     8941 aggagggcac atttggccct tgattggtat tgcttttttt gcctaccaat cagttggagc
     9001 tttgttgcgt cgccacttaa cttcagcctc ttttacagct ctagtagcct taatgattgc
     9061 taaccacttt tatggcattt taccgattcc aaaccagaca ctaatctggg caggagttct
     9121 aatcgttctc ggagtaaata tgttgactca ttctaacaga acttggaatg ggaaaaaatg
     9181 gtggtatgat ggtgaaaaaa acattcttat agataaggaa gttgcttttg ggacagggac
     9241 tttctacaag caagaccaag aattggtaga agaccaagta gaagttggtt ttggcaatgc
     9301 aaaaatctac tatgacaatg cagagatgtt aggtgatttt gcaactttaa atattgaagt
     9361 agcttttggt aatgcaactg tctatgttcc gcaacactgg cgtgtcgatt tgaaagtaga
     9421 aacatccttt ggtacagcca aggcggacgc tcctgtagcg ccaacaagca aaaccttgat
     9481 tattcgtgga gacgtggcct ttgggaagtt ggagcttgtc tacgttaaat aaaaaaatct
     9541 tcacttaaac catcaaaata gacgtactaa gagtaggaaa ttgatgcctt gctctgattt
     9601 cagttctatg gttgttagac tttaaaaaat gaaatgttgc ctttaaaagt tgtatatttt
     9661 tcgatatttt gactcttacg tttgatgtat ctatgtccta cagcgtggat gatgtagtgt
     9721 aaaatgcttt aaaaaaaaaa tgaatgatat tggacagttt ttttgaactt ttaattgctc
     9781 aggagccatg aaagcaagcg cttgggttta tgacaaggga gaatggtatt atgtaagttc
     9841 ttctggttcc atgattgcga atgattgggt caaagacaat ggcaagtagt attatctggc
     9901 ttcatcaggt aagatgcttc gcaataccta cacacctgat agttactacg ttggcaactt
     9961 aggtgcctgg caataagaat aatactcttc gaaaatctct tcaaaccacg tcagcttcat
    10021 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tctatctaca acctcaaagc
    10081 agtgctttga gcagcctgcg gctagcttcc tagtttggtc tttgattttc attgagtata
    10141 agaagtcctt ttccttaaag gaagaggctt tttacttgct tttttgctgt ttcctcattt
    10201 gtcctaaagc cttttttgtg ttaaaatgaa tggtatgaaa gctaaaaaaa tgtggatggc
    10261 aggtctggct ctgcttggta ttgggagcct tgcccttgct acgaaaaaag ttgcagatga
    10321 ccataagctc atgaagactc aggaagagtt gacagcgatt gtacgagacc atttttcaga
    10381 catgggggaa attgcgaccc tctatgttca agtctatgaa agcagtctag agagcttgct
    10441 tggtggcgtt atttttgagg atggccgtca ttataccttt gtctatgaaa atgaagacct
    10501 agtctatgag gaggaagtct tatgatacaa ccagcaagtt tagaagaatt ggcatcttta
    10561 gtagaaaaag acggtaagaa ggtcttcctt tttgtggcgg actggtgtgg cgattgccgt
    10621 tatatctatc ctgccttacc agaaattgag gagagtaatc cagagtttac ctttattcga
    10681 gtggatagag accagtatat agatttggcc aaactctggg atgtatatgg aatccctagc
    10741 cttgttgttc tagaaaagga caaggaaatc ggtcgttttg tcaatcgcga ccgtaaaagc
    10801 aagcaacaaa ttaacgattt tttagcagga ttgaaatagg agaaaaagga aacaatgatt
    10861 tttacatata acaaagaaca tgtcggtgat gtccttatgg tcatcgtgaa aaatagcgga
    10921 gatgctaaac tgaatgtgga acgcaaagac aaggtagccc gtgttttcct caaagaaaat
    10981 ggggaaacag tagcttggaa catttttgag gtttcgagct tgtttgaaat tgcagagcgc
    11041 ggtcaagtct ttttatcaga tgagcaagtc gctcgtttga accaagaatt acaggcggaa
    11101 ggttttacag aagaaattgt taatgataag gaacctaagt ttgttgttgg tgaaattgtc
    11161 gagatggtag ctcatccaga cagtgaccac ctcaacatct gccaagttgc agtcgcaagt
    11221 gacaagatag tgcaaatcgt tgcaggagca cctaatgcgc gtgttgggtt gaaaaccatt
    11281 gtggctcttc ctggtgccat gatgccaaaa gggaatttca ttttcccagg cgaacttcgt
    11341 ggtgaaaaga gttttgggat gatgtgtagt cctcgtgaat tgcatttgcc aaatgctccg
    11401 caaaaacgtg gggtgcttga attatcagaa gaccaagttg tcggaacacc gttcgaccca
    11461 gcgaaacact ggactgccta ggaacttgtc agcatctgat agaaggaaat aagatggcaa
    11521 aaaatgtagt gattacggga gcaacctcag gaatcggtga agcgattgcg cgtgcttatc
    11581 tggagcaggg tgaggatgtc gttctaacag gacgacggat agacagatta gaaatcctca
    11641 agtcggagtt tgcagtaagc tttccaaatc aaaccgtctg gacttttcca ctagatgtga
    11701 cggatatggt catggtgaag actgtttgct ctgatattct agaaacgata gggaggattg
    11761 atatcttggt caacaacgcc ggactggctc ttgacttggc tccctatcaa gactatgagg
    11821 agttggatat gttgaccatg ttggatacca atgttaaagg tctgatggcg gttactcgct
    11881 gtttcttgcc agcaatgata aaagtcaatc aaggtcacgt tatcaatatg gggtcaaccg
    11941 caggaatcta cgcctatgct ggtgccgctg tttactcagc taccaaggca gcggttaaga
    12001 ccttttcgga tggactgcga attgatacca tcgcaacgga tatcaaggtg acaaccattc
    12061 agcctgggat tgtcgaaaca gatttctcaa ctgttcgttt tcatggtgat aaagagcggg
    12121 ctgcgtccgt ttaccaagga atagaagcct tgcaagctca ggatattgca gacatagtag
    12181 tctatgtgac cagtcagcct cgccgtgttc agattacaga tatgaccatt atggccaatc
    12241 aacaggcgac aggtttcatg attcataaaa aataagaaat ttcctcgaaa agttacaaat
    12301 ttctgtaact ttttttgatt tcctacgaat agataagtag gaggaagaaa atatgtataa
    12361 taaagttatc atgattgggc gtttaacgtc tacaccagaa ttgcacaaaa ccaacaatga
    12421 caagtcagta gcgcgagcaa ctatcgctgt caaccgtcgt tacaaagacc aaaacggtga
    12481 acgtgaagct gattttgtca atatggttct atggggcaga ctagcagaaa ctttggcaag
    12541 ctacgcaacc aaaggtagtc tcatttccgt tgatggagaa ttgcgtaccc gtcgctttga
    12601 gaaaaatggt cagatgaatt atgtaaccga agtccttgtg acaggattcc aactcttgga
    12661 aagtcgtgcc caacgtgcta tgcgtgaaaa taatgcaggc caagatttgg cagatttggt
    12721 cttggaagag gaagaattgc cattttaaga attaaaaagt ctgagttggt ctcaggcttt
    12781 ttatcttgag aaagtcagac ttttttcttg actatttctg accaagtgat acaatagaat
    12841 tatgaattag cactccagtt caaagagtgc taataatatc tatctcatta tggaggaaat
    12901 cagatgttga aaccattagg ggaccgtgtg ctcttaaaaa tagaagaaaa agaacaaacc
    12961 gttgggggct ttgtccttgc aggctcagcc caagaaaaaa ccaaaacagc tcaagttgtg
    13021 gctactggac aaggtgttcg taccttgaac ggtgacttgg ttgctccaag tgttaaaact
    13081 ggagatcgtg tcttagttga agcccacgca ggtcttgatg tcaaagatgg cgatgaaaag
    13141 tacatcatcg taggcgaagc taacattttg gcaatcattg aggaatagaa ggagaaagta
    13201 agtatgtcaa aagaaattaa attttcatca gatgcccgtt cagccatggt tcgtggtgtc
    13261 gatattcttg cagacactgt taaagtaacc ttgggaccaa aaggtcgcaa tgtcgttctt
    13321 gaaaagtcat tcggttcacc cttgattacc aatgacggtg tgaccattgc caaagaaatc
    13381 gaattggaag accattttga aaatatgggt gctaagttag tatcagaagt agcttctaaa
    13441 accaatgata tcgcaggtga cggaactacg actgcaacag tcttgaccca agctatcgtc
    13501 cgtgaaggaa tcaaaaacgt cacagcaggt gcaaatccaa tcggtattcg tcgtgggatt
    13561 gaaacagcag ttgccgcagc agttgaagct ttgaaaaaca acgccatccc tgttgccaat
    13621 aaagaagcta tcgctcaagt tgcagcagta tcttctcgtt ctgaaaaagt tggtgagtac
    13681 atctctgaag caatggaaaa agttggcaaa gacggtgtca tcaccatcga agagtcacgt
    13741 ggtatggaaa cagagcttga agtcgtagaa ggaatgcagt ttgaccgtgg ttacctttca
    13801 cagtacatgg tgacagatag cgaaaaaatg gtggctgacc ttgaaaatcc gtacattttg
    13861 attacagaca agaaaatttc caatatccaa gaaatcttgc cacttttgga aagcattctc
    13921 caaagcaatc gtccactctt gattattgcg gatgatgtgg atggtgaggc tcttccaact
    13981 cttgttttga acaagattcg tggaaccttc aacgtagtag cagtcaaggc acctggtttt
    14041 ggtgaccgtc gcaaagccat gcttgaagat atcgccatct taacaggcgg aacagttatc
    14101 acagaagacc ttggtcttga gttgaaagat gcgacaattg aagctcttgg tcaagcagcg
    14161 agagtgaccg tggacaaaga tagcacggtt attgtagaag gtgcaggaaa tcctgaagcg
    14221 atttctcacc gtgttgcggt tatcaagtct caaatcgaaa ctacaacttc tgaatttgac
    14281 cgtgaaaaat tgcaagaacg cttggccaaa ttgtcaggtg gtgtagcggt tattaaggtc
    14341 ggagccgcaa ctgaaactga gttgaaagaa atgaaactcc gcattgaaga tgccctcaac
    14401 gctactcgtg cagctgttga agaaggtatt gttgcaggtg gtggaacagc tcttgccaat
    14461 gtgattccag ctgttgctac cttggaattg acaggagatg aagcaacagg acgtaatatt
    14521 gttctccgtg ctttggaaga acccgttcgt caaattgctc acaatgcagg atttgaagga
    14581 tctatcgtta tcgatcgttt gaaaaatgct gagcttggta taggattcaa cgcagcaact
    14641 ggcgagtggg ttaacatgat tgatcaaggt atcattgatc cagttaaagt gagtcgttca
    14701 gccctacaaa atgcagcatc tgtagccagc ttgattttga caacagaagc agtcgtagcc
    14761 aataaaccag aaccagtagc cccagctcca gcaatggatc caagtatgat gggcgggatg
    14821 atgtaagctt tctatagaaa acaacttata aaaaacacaa aaggagggaa tgactaaccc
    14881 ttctttttat aatattcact tctaaattga tttgagctct cctaacttat atgataaaat
    14941 aagactagaa aaaggagaag aacatgatcg atgtagaaga aattctgtgc aagatgaccc
    15001 ccaatcagaa gattaattat gaccgtgtca tgcagaaaat ggtacaagca tgggaaaaaa
    15061 atgagtagcg gccaaccatt ctcgtgcatg tttgctgtgc cccttgtagt acctatacac
    15121 tagaatattt gaccaagtat gcagatgtga ccatctattt tgccaattct aatatccatc
    15181 ccaaggcaga ataccataag cgggtctatg tcaccaagaa atttgttagt gattttaatg
    15241 agcggacagg aaatacggtt cagtacctag aagctcccta cgaacccaat taataccgaa
    15301 aactagttag ggggctagag gaggagcccg aaggtggcga ccgttgcaag gtttgttttg
    15361 actaccgact ggataaaaca gcgcaagtgg ctatggactt gggctttgac tactttggtt
    15421 cagccttgac catcagtcct cataagaatt ctcaaactat caatagcatc ggaatcgatg
    15481 tgcaaaaaat ttacacgccc cactattttc ccaacgattt caagaaaaat caaggctaca
    15541 aacgttcagt agagatgtgt gaggagtatg atatctatcg tcaatgttat tgtggctgcg
    15601 tctatgcagc ccaagcccag aatattgacc tggtttaagt taagaaggac gccacagcat
    15661 gcttgttgga taaggatgtt gagaaagact attctcatat caaatttata gtagattgaa
    15721 actagaatag tacaccttta cttctaaaac attgttagaa atcgatttga ctgtccttat
    15781 ttcattttac tatactgtta cgaaattaga tatataaatg aaaacttgcc tcaaggtagg
    15841 ttttttgcta gtagaaaagc gatagacaga aattgttgga ctcttaaaaa aatgaagttt
    15901 tgctcaaaag agctttttaa attaaaacga gcaattatca gttcaaatct gtttcaaaag
    15961 aagaacggat aaattaatcg atgctttgtt tttgagttag gaagttaagc atgccaaact
    16021 gagtcgtagg aataaatttc tttatagaaa tgtgttacaa ctctgctata acggaatatt
    16081 ccttttttgc atttatataa cttatttaac actatcttta ttcttgtgat ataatgccaa
    16141 attatagagt ggaggtcatt taaaatgatt gataaagtaa ttgaacaata taaaagtcat
    16201 gataatcttg atattcgagt agaattgcat aagaagtatt caaaaaataa attgggattt
    16261 aataattgga tattttctaa ctaccaaatc actgatgaag taaaggttct agaattggga
    16321 tgtggtacag gagaattgtg gaaaagtaat agtgattcta tagataaaat gaagcagttg
    16381 attgttacag atttttctaa agatatggta aaatcaacga agtcagtgat tggaaataga
    16441 aacaatgtca attatgagat aatggatatt caaaagattt cttttgagaa tgaaactttt
    16501 gatattgtta ttgctaatat gcttctacat catgtgaatg atattcctaa agctctctct
    16561 gaggtgaata gggtcttaaa aaccggaggc attttttact gtgctacatt tggtgaaaat
    16621 ggagttgtaa attatttggc aagtttattt aaagatgagg ttaatcaaga tttagaaaat
    16681 agaacgttta ctttacaaaa tggtaaaagg tacctgagta ggtattttaa ctctgtcgat
    16741 acattactct atgatgatga gttacaggta actagtatag atgacctagt taaatacatc
    16801 caatcgttta aaggaatttc agaaataggt tcactagaag aggaaataat acgtaaaaga
    16861 ttggaaagtg agtttaataa tggtatgttg atcattccta aagaatatgg tatgtttatc
    16921 gctcgaaaag aaagttaagg gaatgaaagt gtgaaaaatt acggagaagc ttttcgatat
    16981 tttagaaaat taaacggata ttctttagag tatgctgcag ctgattttat atcaaaatct
    17041 caactttcta gatttgaaag gggagaaaat gaaatttctc tttcaacatt ttttgaatta
    17101 ttatcaaata tcaatgtttc gatagagaat tttt
//
LOCUS       DAVKZI010000041        15907 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKZI010000041 DAVKZI010000000
VERSION     DAVKZI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.042"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..1980
                     /locus_tag="VXB18_001687"
     CDS             1..1980
                     /locus_tag="VXB18_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0382858.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDATERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            1990..2304
                     /locus_tag="VXB18_001688"
     CDS             1990..2304
                     /locus_tag="VXB18_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0382859.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            2335..2841
                     /locus_tag="VXB18_001689"
     CDS             2335..2841
                     /locus_tag="VXB18_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382860.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            2921..4267
                     /gene="celB"
                     /locus_tag="VXB18_001690"
     CDS             2921..4267
                     /gene="celB"
                     /locus_tag="VXB18_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0382861.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            4646..4822
                     /locus_tag="VXB18_001691"
     CDS             4646..4822
                     /locus_tag="VXB18_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382862.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            5223..7436
                     /locus_tag="VXB18_001692"
     CDS             5223..7436
                     /locus_tag="VXB18_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HEV0382863.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFVQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDEADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETENVPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYKLEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(7658..8134)
                     /locus_tag="VXB18_001693"
     CDS             complement(7658..8134)
                     /locus_tag="VXB18_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0382864.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            8357..11557
                     /locus_tag="VXB18_001694"
     CDS             8357..11557
                     /locus_tag="VXB18_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0382865.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPFSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            11937..12322
                     /gene="tnpA"
                     /locus_tag="VXB18_001695"
                     /pseudo
     CDS             11937..12322
                     /gene="tnpA"
                     /locus_tag="VXB18_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(12701..13330)
                     /locus_tag="VXB18_001696"
     CDS             complement(12701..13330)
                     /locus_tag="VXB18_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0382866.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(13340..14341)
                     /locus_tag="VXB18_001697"
     CDS             complement(13340..14341)
                     /locus_tag="VXB18_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0382867.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLSGDHLSTSATSIENLLANAQDIIR"
     gene            complement(14372..15013)
                     /locus_tag="VXB18_001698"
     CDS             complement(14372..15013)
                     /locus_tag="VXB18_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0382868.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(15032..15847)
                     /locus_tag="VXB18_001699"
     CDS             complement(15032..15847)
                     /locus_tag="VXB18_001699"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0382869.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         5094 a         2602 c         3307 g         4904 t
ORIGIN      
        1 atgaatgtgt taaacattaa agagaaagat atccttcaat ttttaataaa aaataaggaa
       61 cgttttgtta caagcaaaga actagcagaa tatttatcct gttcagatag aactgtccgt
      121 aatgtactga aattaattga gaagacaatg attattcaag gagtccggtt gatttcaaaa
      181 caaggtcaag ggtatcaaat attttttgag aatcaaggcg cttaccagga gtttagacaa
      241 acttatgaac tggaagaaga ctatacgaaa actgcggttt caaaaggtga tgatcgttta
      301 gtatttatct taaataaatt attatttgag caagttccag ttctttttga tgatttagct
      361 gatgaacttt acgttagtcg ttcaacatta tctcatgatt tcagaaagat acgagtgatg
      421 ttatcagagt ataatttgtc cattgagagt agggcgaata aaggagttta tgtctcaggc
      481 gaggaacgtg ataaacgacg ttttatcata aattatttcc tagagaatca attttttaaa
      541 acaatacatt gctatgtaaa atttaacttt tttgatcaaa ctgttccatt agaagaattt
      601 gctagaattg ttttggatga atgccaagag gccaacctaa aactatctga ttttgtacta
      661 cagaatttag tagttcacat agcattgtct gtgattcgtt taaaatccgg atttgaaata
      721 aaaaatatag actgtcagat gactgatgat gcaacagaga gaaaggttgc ccaaagaatt
      781 ctttctaaag taagagaagt aacaaatcag gaatttccag ttcaggaaat agactacatt
      841 actttgcatt tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa tatttctgaa
      901 gaagttttaa aaaaatcttt atttaaaaca tttcagaatt taggattaga tgatatgtat
      961 aacttttctt cagatttcca actaattgaa ggattgataa ctcatctaat gacactacaa
     1021 gtacgtttag aaagccggat taccttaaat aaccctttag tagatgaaat taaacagaat
     1081 tatagtgata tattctttat gactagagaa attcttgcaa atatggacaa gttcttggag
     1141 tggacaatat cagatgatga agtagcatat gtaagtcttc actttttagc tgctatggaa
     1201 cgtagcaaag agagtactaa gtttaatatt cttgctattt gtgcaacagg atttggtgca
     1261 gcccaaatgt taagaaatcg tttggaaacg gagtttggga agcgagtaga agttgttgat
     1321 gtaataggct actatgaatt gaatcaagaa aaacttaaag gaatagattt tatagtgtca
     1381 gctgttgatt tatcaaatct atattttcaa atcccagttt ttaaagttag tgtgtttctt
     1441 aaaagtgatg agatggaaat gattagaaaa gctatggatc agatgcaagt ttctagttat
     1501 gtacaatcat caaagattaa caaatttgaa aacaacggct ttagacagta ttttagtaaa
     1561 gaaaattttt taatatgtac tgaatcagac aaggtaaatt tacttgaaaa gatggttgag
     1621 ggtttatctg ttggtgaatc aaatgagttt gaacaatctt tactttatgg aattaaacag
     1681 cgcgaagaat taagttcagt tgttttttct gaaaaaattg cagttccgca tcctattcag
     1741 ccctttggta cagagggaaa ggtttcggtt gcaatttgta aagattcgtt actctgggat
     1801 aatcaaagtt cacatgtcca gctagtattt cttctatctc catcaatata tgggaacgaa
     1861 ggtttagcaa ctgtgactaa aaagatagtc tctctgacag agaatgatga attgcaaaat
     1921 cagctaatat cttgcaataa ctttgaagat tttatcaaca tatttgagaa gataaaatag
     1981 gaggttcata tgaatcaaga ggaactgcag gttgcagcat ttgaaattat cctgcattcg
     2041 ggaaatgcaa ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg tagttttgat
     2101 gatgcagaaa gtaaattaaa tcaatcaaat gagataattc ttgaagcgca tcatgcacaa
     2161 accaaactct tgcaagaata cgcaagtgga gtggaaatta aaattgaaat tatcatggta
     2221 catgctcaag atcatttaat gaccactatg acattattag aagtagcaaa ggaaatgtta
     2281 gctctttata agaaagttaa ctaaatatgt gttgttatat aaggaggaaa tgatatggat
     2341 aaaaaagaac gacaaaaaat tgaacaacaa cgtcgagaga tggctctaac taatactttt
     2401 tttaatcgat atcttcttct acgttattca atagctctct tcttttttgg gaatatttat
     2461 tggcttttga atcagtttat taatccctcg cctattatta ttttccccat tatgctcata
     2521 gtattttcta ttttagcaac tattgaacaa tttaaacttt atggaaatag gaaagaaaag
     2581 ttgggaataa cactaatgtt tgttagaata caaatgctta tttcaatagg attacttgtt
     2641 ttaacttgga caagttggtt taagaatctt tttccgattt ttgaaaataa ccaagtagca
     2701 cgtttatttg tttttgtagt tcttctatta ggtttagttc tgagtttgtt agacattaga
     2761 agaattaaaa aaatttataa acgaacagat aaggcttatc aacaatttgt ccaattggaa
     2821 aagaactcac ttagtttata atcctgatct agtataattt gtatttgaaa ctagtcttta
     2881 gaaagtaaaa attattatgt tttattaagg aggtctattt atggatcaac aaaacgggtt
     2941 gtttggtttt cttgaaaacc atgttatggg accaatgggc aaacttgctc agtttaaagt
     3001 agtgcgtgct atcacggctg caggtatggc tgctgtacca tttactattg taggatcaat
     3061 gtttttggta ttcagtattt tgccacaagc tttctcattt tggccaattg tggcagatat
     3121 tttctctgct tcatttgata aattcacatc actttacatg gttgcaaact atgcgactat
     3181 gggttctcta tctctttatt tcgttctatc acttgcatat gaattgacaa aaatttatgc
     3241 agaggaagaa gaactcaata tgaatcctct taatggtgcc ttgctcgcct tgatggcttt
     3301 tgtcatgaca gtaccgcaaa tcatttttga tggtggaatg atgaagactg tgacaagtct
     3361 aaaagaaggt gcagtaattg cagatggatg ggcaatggga aatggagtcg cacgttttgg
     3421 gacaacaggg atttttaccg caatcattat ggcaattgtg actgttctta tttatcgtat
     3481 gtgtgttaaa cataattggg ttattaaaat gcctgaagct gttccagaag gagtttctcg
     3541 tggatttacc gctttggttc cgggatttgt tgttgcattt gttgttatct ttatcaacgg
     3601 tcttcttgta gcaatgggaa cagatatttt taaagtcatt gcaattccat ttggttttgt
     3661 atccaatctg actaattcgt ggattggttt aatgattatt tatctattga ctcaactact
     3721 ttggattgta ggtatccacg gtgcgaacat tgtttttgca tttgttagtc caattgctct
     3781 tgctaacatg gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg aattttctaa
     3841 tatgtttgta attgcaggtg gttctggtgc aactttagga ctatgtttat atattgcttt
     3901 tgcctctaaa tctgaacagc ttaaagcaat aggacgagca tctgtagttc cggccttatt
     3961 taatattaat gaaccattaa tttttggatt acctattatc tataatccag ccttggctat
     4021 accatttatt ttagcaccaa tggttactgc tactatttat tacgtagcga attctctaaa
     4081 ctttattaag ccaattatcg cacaggttcc atggccaact ccagtaggga ttggagcttt
     4141 cttagggaca gcagatcttc gagctgtatt agttgctcta gtatgtgcat ttgcagcatt
     4201 cctagtctat cttccattca tccgtgtata tgatcaaaaa ttggtgaaag aagagcaagg
     4261 tatctaataa gtaaaaaagt atactcgatg atagaatcca tatagtttaa ataatgagtg
     4321 ttaatattag cagtgaagag gtctttttaa gatattcttc tctgcttttt catatttttt
     4381 cgctatgtag ggtatgaagc aaaatagaaa gtagttcgaa tagttgataa acagggaact
     4441 gctgttattt aaaaaaacaa taaagtaaag tatgttatcg tagaatacga tacaatagta
     4501 aaaaagcaaa aagaatgcgt tttatatttg ggtttgaggt ttataaaata ggataagcgt
     4561 gctgaaaact tagatatgac aaacaaaata aaatttttaa aagctacaga gaaacatggt
     4621 ataatgtatc taaaggaggt agcatatgtc cttagatata gataaagaaa agatgacaat
     4681 catgggaata gcttttgaaa accgatccgt ttttaagagt gtttggtatg ctttaagtac
     4741 aaatatgatt gaaggatggc gacctacggt tagtgatgtt gaaaaattac gagatgaagc
     4801 tcttgctctg gggatgactt aatgaagcgc aactgttatg aatcttatga ctatgttgat
     4861 ccggataatt tatataccga tccgggttct tcagttctaa gaaataagca ggaaggaaaa
     4921 aagcacgcga gcttgaatat cgtatgattg ctagtaagag tttgaaatta tttatcaatc
     4981 ctatcttagt taatagttta aaagtagttt gtttcacaac tgcataagct tagaaaagtt
     5041 gaaaagtgat aactctttaa taaactcttg gtttgttaaa agatattttg tccactacat
     5101 tttttcaatt gactattatt tgtcatagat ataacagata gaacattgca ttcagaataa
     5161 tgaaaaacgc atcaaaaatg gtgcgttctg tttttatgct accataaaag gagggaaaca
     5221 aattgaaaat ttttaaggga gagttttatc gaatctctgt attaacagac aagttagtaa
     5281 ggttagaata ctctcaaact ggaagttttg aggatagaac gacacaactt atctataata
     5341 gagattttgt ccaagtttcg ttagattata tcgagacatc aaacgtacta gatattatga
     5401 cggactattt tcatttgcat tttaataaag gagaatttaa cgccgaaaat ttatttatag
     5461 aattaaaagg aaattttgcc gtatatggta gtcgctggta ttttggtgaa tctattgaaa
     5521 cgttaaaagg aacagctcgg actctggatg aggcagatgg agcaatctcg ttagaagatg
     5581 gaattattag ccgaaatggt atagccttat tggatgattc tcaaggattt atttgggatg
     5641 aacagtctgg ttatattgag agagaaaatc aaattgatct ctatttcttt gcctatgggc
     5701 atgattatag aggagcaatc agagactttt accatttgac tggttcaaca cccttgttgc
     5761 caagatatgc tttaggcaat tggtggagta ggtattggcc ttatacgtca gatgaatact
     5821 tggatttaat agacagattt gaaacagaga acgttccatt atctatcggt gttttagata
     5881 tggattggca tataactgac attccagctc gttttggaag tggctggaca ggatatagtt
     5941 ggaataaaaa cttaatacct aatccagaac agttattgca acaacttcat gatagaaagt
     6001 tgaaactctc cttaaatgtc catcctgctg atggtatacg ggcttatgaa gaagcttatc
     6061 ctcaagtcgc aaaacgattg gggttaaatg tagaactaga agaacctgct atttttgatt
     6121 tttttaatcc atcttttaga gaagcctact ttaaagatgt tcattataag ctagaaaagc
     6181 agggagtaga tttttggtgg attgactggc aacaggggac tcaaggcatg ttggatccac
     6241 tgtggctttt aaatcattat cactatcagg atagttgtaa aaatgcagaa ggtggtttga
     6301 ttttatcaag atatgcaggt cctggtagtc accgctaccc tgttggtttt tcaggggaca
     6361 ctattattag ttggaattcc ttaagatttc aaccttattt tacagcgaca gcatcaaata
     6421 tcggttatag ttggtggagc catgatatcg gtgggcacat gctgggggat tatgacgaag
     6481 agctgcaaac tagatggcta cagtttggtg tttttagtcc gatcactcga ttacatagtt
     6541 ctagaagtcc ttttaatagt aaagaacctt ggtttttttc agaaacaaca tctaagatta
     6601 tgaagaaata ccttcgtttg aggcatcaga tgattccata tctatacact atgaatgtaa
     6661 agacacacga ggaaggtgcc ccattaatca gcccaatgta ttatttctac ccagagaatg
     6721 atgagagcta taatgttcca aaccaatact tttttggaac agaactaatg gtggctccca
     6781 ttgtagaaaa gatggacttg gcattccaat ctgcaaaagt ggatgtatgg ttccctgaag
     6841 gtgaatggta tgacttcttt tcagagaaaa aatatacagg tggtgtgaag ttgagtgttt
     6901 atagagacat ttcgactata cctgtgtttg caaaaagtgg tgcgatcatt cccttggttg
     6961 gttctgagat agatatgggt gttgatttac ctgaagttgt agattggtat gtattcccag
     7021 gcaaacaaca ttcttttgaa atgcttgaag atcaaaatgg tcaaagatat aaaacaagat
     7081 tatcaatcga ttgggaaatg gggatggtag agttaacatt acaaggagat tctagtatcg
     7141 ttccaagcaa tagaaggcat agaattcatt ttaaaggaac gaatgtgtct ataattgaat
     7201 taccaaataa gaatgataca gctagatttg aatgtaaaga taataaaaca atatctttaa
     7261 atgatgaagt ttttagacta ctaaagacag cttctcttcc atatgaatta aaagatagat
     7321 tgttaaatca attcatcaat gcgaaaaact ctcatgactt aatgaatatc ttgcatcatc
     7381 aggataagga attgagaggg cgtttgttgg aaatgatatt tactagccaa aactaattga
     7441 tataattaga aagtcatttg tttagtgtat atgaagattc tgtatggtat tcgttatcac
     7501 tggtcacatt gaaaatgtga aataagcacc tacaacatag actttacaac acttcatgtt
     7561 tcatatcatg gggtgttttt ctatttaagt caaagccaat caaaaaatct cactattcat
     7621 caggttaaag gaaacctaat catagtgaga ttgtgaatta tagtagagtt tgtatcgcct
     7681 cttcaatttg ttttgggtct gtttttgaag aaaagcgttc aaagacttgc ccatctcgac
     7741 cgatgagaaa cttagcgaaa ttccattcga ttcgttttcc tagtgggccg gatttctggt
     7801 cttttaacca gacatagaga gggtctgctt ccttaccgtt gaccttaatc ttggcaaaac
     7861 gtgggaaggt ggtttgaaaa tgtaggctac agaaggcgtt gatttcctct gcgctgccgg
     7921 gtgcttgtcc cataaactga ttgcaaggga aatccaatat ttcgaagccc tgatcttgat
     7981 agcgttcata gagttcttga agtccctggt actggggcgt taaaccacat ccagtagcag
     8041 tgttgacaat caagagaact ttgccacgat agctatccaa gggagttgct tggttgtttt
     8101 ggttcaaaac ggaaaaatca taaagtgaag tcatgagggc ctcttttctt tttctacatt
     8161 gtaacagttt ttactttttt cgtcgagtcg gatggaagat attgttgaag aataagcctt
     8221 caatatgata gaaaccgttt acaaataact ttaaaaatgg tatgatttaa ttaaaccggt
     8281 ttacttagtt gctataaatc tctaatttga gatttagttc ctattgattt tacaatatgt
     8341 ttattggagt gtatacatgc aaacaaaaac aaagaagctc attgtgagtt tgtcttcact
     8401 tgttttatca ggatttttat taaaccatta tatgacagtt ggagcggaag aaacgactac
     8461 gaataccatt cagcaaagcc agaaggaagt tcagtatcag caaagggata caaaaaattt
     8521 agttgaaaat ggtgattttg gtcagacgga ggacggaagc agtccgtgga caggaagcaa
     8581 agctcagggg tggtcagctt gggtagacca gaagaatagt gcagatgcct caactcgagt
     8641 cattgaggct aaggatgggg ctatcactat ctcaagccat gagaaattaa gggcagcggt
     8701 tcaccgtatg gttcctattg aagctaagaa aaagtataaa ctgcgtttca agattaaaac
     8761 agatcataaa gtcgggattg ccaaagttcg tatcattgag gaaagtgata aggacaagcg
     8821 attgtggaat tctgcaacga cgtcaggaac aaaggactgg cagaccattg aagcagacta
     8881 tagcccgact ttagatgttg ataaaatcaa gctggagtta ttctatgaaa caggaactgg
     8941 gactgtttcc tttaaggata ttgagctggt agaggtagca gaccagcctt ctgaggacta
     9001 tcaaacagat aaacagcttg aggaaaagat tgatttacca attggaaaaa aacatgtttt
     9061 ttctcttgcg gactatactt ataaggtaga aaatcctgac gttgcttcag tcaaaaatgg
     9121 aattttagaa cctcttaagg aagggacaac caatgtcatt gtcagtaaag atggcaagga
     9181 agtgaaaaag attcctttga agattctagc ctctgttaag gatgcataca cagaccgttt
     9241 ggatgactgg aatggcatca tcgctgggaa tcaatactat gattctaaaa atgaacagat
     9301 ggccaaatta aaccaggaat tggaaggaaa ggtagctgat agcctatcta gtatttcaag
     9361 tcaggcggac cgcacctatt tgtgggaaaa attttcaaat tataaaatgt ctgcaaatct
     9421 gactgccact tatcggaaat tggaggagat ggccaagcaa gtgaccaatc ctttttctcg
     9481 ttattatcaa gatgaaactg tcgttcgaac agtcagggat tccatggaat ggatgcataa
     9541 acatgtctac aatagtgaaa agagcattgt tgggaactgg tgggattatg aaatcggtac
     9601 acctcgtgcc atcaacaata ccttgtctct gatgaaagaa tacttctctg atgaggaaat
     9661 taaaaaatat acagatgtga ttgaaaaatt tgtaccagat cccgaacatt tccgaaagac
     9721 gactgataac ccatttaagg ctctaggtgg aaacttagtt gatatgggaa gagtaaaagt
     9781 aatagctggt ttactgcgta aggatgatca agaaatttct tctaccattc gctcgattga
     9841 gcaagtgttc aagttggtag accaaggtga aggtttttat caagatggat cctatatcga
     9901 ccataccaat gttgcctata cgggtgctta tgggaatgtt ttgattgatg gcctgtctca
     9961 actgttgcca gtcattcaaa agaccaagaa tccaatcgat aaagataaaa tgcaaaccat
    10021 gtaccactgg attgataaat cgtttgctcc tttgctggtg aatggagagc tgatggatat
    10081 gagtcgtgga cgctcgatca gtcgtgcaaa tagcgagggg cacgtggccg cagtagaagt
    10141 actaagaggg attcaccgaa tagcggatat gtctgaagga gaaaccaaac aacgtttgca
    10201 gagtcttgtg aagaccattg ttcaatcgga tagttattat gatgtcttta agaatttgaa
    10261 gacttataag gatatcagtt tgatgcaatc cttgttaagt gatgcaggag tcgcaagtgt
    10321 tccaagaaca agttacctat ctgcctttaa caagatggat aaaacagcca tgtacaatgc
    10381 agagaaaggg tttggatttg gcttgtcact cttttccagt cgtaccttga attacgaaca
    10441 catgaacaag gaaaataaac gtggttggta tacgagtgat gggatgttct atctttacaa
    10501 tggcgatttg agtcactata gcgatggcta ctggccaaca gttaatccat ataagatgcc
    10561 tggtacaaca gagacggatg ctaagagagc ggatagcgat acaggtaaag ttttaccgtc
    10621 tgctttcgtt ggaacgagca aactagatga tgccaatgcg acagcaacca tggatttcac
    10681 caactggaat caaacattga ctgctcataa gagctggttt atgctaaagg ataagatcgc
    10741 ctttttagga agcaatatcc aaaacacttc aacagatact gctgcaacta caattgacca
    10801 gagaaaactg gaatcaagta atccatataa agtctatgtc aatgataaag aagcctccct
    10861 tacagaacaa gaaaaggatt atcctgaaac ccaaagtgtc tttttagaat catccgattc
    10921 gaaaaagaat attggttact ttttctttaa gaagagttca atcagtatga gtaaggcttt
    10981 gcaaaaggga gcctggaagg atatcaatga aggacagtca gacaaggaag ttgaaaatga
    11041 atttcttacg attagtcagg ctcataagca aaatggagat tcttatggct atatgctcat
    11101 ccctaacgtg ggtcgtgcca ccttcaatca aatgataaaa gagttagaaa gtagcctcat
    11161 cgaaaataac gaaacccttc agtctgttta tgatgccaaa caaggagttt ggggcattgt
    11221 gaaatatgat gattctgtct ctactatttc caaccaattc caagttttga aacgtggagt
    11281 ctataccatt cgaaaagaag gggatgaata taagattgcc tactataatc ctgaaaccca
    11341 ggaatcagct ccagatcagg aagtctttaa aaagctagag caagcagctc agccacaagt
    11401 acagaattca aaagaaaagg aaaaatctga agaggaaaag aaccattcgg atcaaaagaa
    11461 tctccctcag acaggagaag gtcagtcaat cttggcaagt ctagggttct tgctacttgg
    11521 ggcgttttat ttattccgta gaggaaagaa caactaattt gttcatcatc tagatgaatt
    11581 acatgaaact gtggaaaata gaaaaaatcc gaagaaggcc aaatatcttc ggatttttct
    11641 tttaaaaaag gataagttga tacttatcct ttttacttca ttatgtgact atagcgtttt
    11701 gaaactagaa taggacatca taactgctaa aagatttcta taaattcatt tgattttcct
    11761 aatcaattta ttcgtatcct atttcactct actatattag tccgtctcgc acctcacgga
    11821 gcgagacaaa acaaccaccc gctatgcggg tgcgcgtcga aggttatacc aaaaaaactc
    11881 caaacgcgat acaataaagg tgttcaatcc acttgtaaag cgaaaggaga aaaaatatgg
    11941 cacaaaaggc tcatagttta tctcacacaa agtggaggtg ttctatcaca ttgtgttcac
    12001 ccctaagtat agacgaaaag tcatctataa tcaatataga agtagtttag gcgaaatatt
    12061 tcatcgcttg tgtagttata aaggtgttga aatgatcgag ggtcacttaa tgccagacca
    12121 tgtacacatg ttagtcagta ttccactaag gctaagtgtt tcgagtttca tgggttattt
    12181 aaaaggaaaa agtgcactca tgatgtttga caaacacgcc aatctcaagt acaagtttgg
    12241 gaatcggcat ttctgggtgg aaggttatta tgtaagtcca gtagggctta atgaagccac
    12301 aattaagaaa tatagtcaag attaaagaaa ttatcgagtg gatgatttct tcacgagtat
    12361 gaaaatttga gaactagtaa agtatgatat atagtaaaat gaaataagaa caggacaaaa
    12421 tcgatcagga cagtcaaatc gatttttaac aatgttttag aagtagaggt atactattcc
    12481 agtttcaatc tactatagca ctagataaat tgagtgtaaa agaatatgag gatcccttta
    12541 gggatagtgg taagtaatac caaagtctct taaagaggca agtgacgagt caagagcaat
    12601 aaggcttgaa caacgtgaaa gccagcgtct ttaggcgctg gctgatgatt tgggcttata
    12661 gctctgggat aaaccacccg ttagacgggt agttatgatt ttatctgagt gtaatatact
    12721 gttgggcaat ctcgctgatg cggtcaaagt tgccttggga agcgagttta ttgagttcgc
    12781 caccaattcc aacggcatct gcaccagcag cgaaccattg agggatgttg tttaggccga
    12841 ctcctccggt taccattacg gaaacttgtg ggatcggtgc cttgactgca gagatatatg
    12901 ctggactgag agtactacct gggaagagtt tgatgatttc actaccggct tcaagtgcag
    12961 tcgtgatctc tgtgagggta atacagcctg gaatgtacgg tgtgctgtag agattgcaca
    13021 ttttcgcagt ttcagcatgg aaagatggag aaacaacgta atttgctcca gctagaatgg
    13081 catctctagc agttacggca tcaagcacag tacctgcacc gatacaaaca ctctgatcgt
    13141 cctgatacaa gtctacaagt tccttgatga tttgtcctgc atactgattg gtataggcga
    13201 tttcaatagc tttgataccg cccttgatac aagcaatcga ggcttgtagt ccttcttcct
    13261 ttgtatttcc tcgaatgaca gcgacaattt tctgtttttt tagttcaata atcgtatctg
    13321 atttggtcat gtaattctcc taacgaatga tatcttgtgc atttgccagt aaattttcaa
    13381 tactagttgc ggaagtggag agatggtctc ctgaaagagt gcatttgaga gttgcgctcg
    13441 caactgcaaa gtcaatggta gtttttaggg aggaatgatg gagtagttgg taaagggcac
    13501 cagatataaa ggcatccccg ctaccaattc gttgatagac tgcagttttt agttggacag
    13561 actcttcaaa tcgttcttcc agagcatagg cttgatagac atttttgtct tgctcatcac
    13621 tagatcggag ggtatggaaa atagccttga aaccataggt ttcttttaaa agtcgcatgc
    13681 gattttccac ctcttctagg ctagcactgt ctcttggaaa catctctaga ttttggtcat
    13741 caatcatgag aggatcaata ccgaagcaat agtcagtaaa acgtgcaaac ttagaaaatt
    13801 catacttggc ttctagggct gaaatcatct ttgttctcag attgagatcc attgaaacga
    13861 caattcctcg gcgcttggct tcttccaaga gtaggagaag gatcgcacgg acctcttgac
    13921 cgatagctat ggtgattcca ctaaaatgaa aatggctaat tccctgaaag agagaatcca
    13981 tatctagcat gtttggccga atctggctga tactcgtatg cttacgatcg tagaaaactt
    14041 cactttgacg acaaccaaag ccgttctcca aatagtagag gccgattcga tcgccaagcc
    14101 gacagattga actggtatcg atttggtgct gtttcaagaa tgtgagaaaa cgatctccaa
    14161 tctcgttggc agggagtgcg gtaaagactt tcgttgagat acccagggct tgcaaattac
    14221 aagcgatgtt aatttctgat ccgccaaaat aagtcgaact ggcaacatga tctccgatac
    14281 tggtggcatc taatggtgag attcgaatta atggttcgcc aaacagtaat attttcgtca
    14341 tccattagtt cctttctggt ttagaatagc tttacttggc taatacttct ttcaaataag
    14401 cagcgacttc atcatcttgg cagttttcaa agaagtattc ttggaaatat ttgccagaga
    14461 tggtgtcttt gaggaagtct tggtcgattg ttttaaggat ggtcatcaaa tcattgtggg
    14521 tgatttgttt cacctcgttt aagatacgag cgttgcgttg ttcagggatt acacgttctc
    14581 ttgggtagcc accgcccatt tcttcagcaa ataagcgttc aaacatcaat ttgagggtca
    14641 gttctgcccc ccagccaaat cctttggcat aagggataga caaggcgtta ccaccattga
    14701 tttgagaata aaggtaagcg tcagttgggt ccactgctag accacagaca acaccaggga
    14761 agctgtttaa agcaagcata gcccctacac ccgtaccaca gccggtaaca acaaagtcaa
    14821 ctgcctttgt atttaaaagg atggcagcca ttagtccgtt ctgcacataa gttaattgac
    14881 tttctccttc ttctccacgc ataccatagt taaataattg gtagtctttt ttatctgtcg
    14941 cttcttttag actatcgtaa ataatgtgat tcttgctagc ttgactattt tcattgatta
    15001 atgcgatttt cataagatct tctttctatt tttactcagg ttgttttccg atgtaggcta
    15061 agataccgcc atctacatat aggatgtggc cattgacaaa attgctggca tcactagcga
    15121 gaaagacagc agggcccatc aaatcttcag gatttcccca acgtgcagca ggtgtttttg
    15181 caatgatgaa ctggtcaaat gggtggcgag aaccatcttc ttgcaactca cgaagaggtg
    15241 ctgtttgagg agtggcaata taacccggtc caattccgtt acattggata ttggctccac
    15301 cgtattcaga cgcaatgttg cgggtcaaca ttttcaaccc ccctttagca gcagcataag
    15361 cgctaactgt ttcacgtccc agttcgctca tcatcgaaca aatattgata atctttccat
    15421 gccctttctt tatcatagaa ggaataactg cctttgaaac gataaatggt gcgtttaagt
    15481 caatatcgat gaccttacgg aaatcagcgg cgctcatttc gcacattgga actcggcgga
    15541 taataccagc gttattaacg aggatgtcaa tgacaccaac ctcttgttcg atttgcttga
    15601 ccatggcttg gataccgtcc tcgtctgtca cgtcacagac atatccatgg gcttcgatgc
    15661 caacttcacg ataagcttca atccctttat tgaccagatc ttgattgata tcgttaaaga
    15721 caatagtagc gccggcttca gcgtaggatt tggcaatagc aaatccaatt ccataagaag
    15781 cgccggtgat gagagcaatt tttcctttta aagaaaactg ctcaattgag aatgatgtat
    15841 ttgtcatttg atacttcctt tcaaatttgt taagacttct ctataaccaa attatattct
    15901 agtaaac
//
LOCUS       DAVKZI010000042        15671 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKZI010000042 DAVKZI010000000
VERSION     DAVKZI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.043"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..537)
                     /gene="nusG"
                     /locus_tag="VXB18_001700"
     CDS             complement(1..537)
                     /gene="nusG"
                     /locus_tag="VXB18_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0382870.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            complement(592..768)
                     /gene="secE"
                     /locus_tag="VXB18_001701"
     CDS             complement(592..768)
                     /gene="secE"
                     /locus_tag="VXB18_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0382871.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            complement(778..930)
                     /gene="rpmG"
                     /locus_tag="VXB18_001702"
     CDS             complement(778..930)
                     /gene="rpmG"
                     /locus_tag="VXB18_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0382872.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            complement(983..3178)
                     /locus_tag="VXB18_001703"
     CDS             complement(983..3178)
                     /locus_tag="VXB18_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0382873.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENISLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            3304..4140
                     /locus_tag="VXB18_001704"
     CDS             3304..4140
                     /locus_tag="VXB18_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0382874.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNFPILGDPLYNSNSKTSRLMLHAFRLSFTHPLTLEKLNFTALSNTFETELKK
                     NG"
     gene            complement(4209..5216)
                     /gene="gap"
                     /locus_tag="VXB18_001705"
     CDS             complement(4209..5216)
                     /gene="gap"
                     /locus_tag="VXB18_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0382875.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(5396..6358)
                     /locus_tag="VXB18_001706"
     CDS             complement(5396..6358)
                     /locus_tag="VXB18_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0382876.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLPHQMETISKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIA
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            complement(6419..7251)
                     /locus_tag="VXB18_001707"
                     /pseudo
     CDS             complement(6419..7251)
                     /locus_tag="VXB18_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(7382..8254)
                     /locus_tag="VXB18_001708"
     CDS             complement(7382..8254)
                     /locus_tag="VXB18_001708"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0382877.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            8490..9800
                     /locus_tag="VXB18_001709"
     CDS             8490..9800
                     /locus_tag="VXB18_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0382878.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(10166..10360)
                     /locus_tag="VXB18_001710"
     CDS             complement(10166..10360)
                     /locus_tag="VXB18_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0382879.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(10819..11547)
                     /locus_tag="VXB18_001711"
     CDS             complement(10819..11547)
                     /locus_tag="VXB18_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0382880.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            11705..13114
                     /locus_tag="VXB18_001712"
     CDS             11705..13114
                     /locus_tag="VXB18_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0382881.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            13132..14427
                     /locus_tag="VXB18_001713"
     CDS             13132..14427
                     /locus_tag="VXB18_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0382882.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            14432..14740
                     /locus_tag="VXB18_001714"
     CDS             14432..14740
                     /locus_tag="VXB18_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0382883.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            14737..15045
                     /locus_tag="VXB18_001715"
     CDS             14737..15045
                     /locus_tag="VXB18_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0382884.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         4863 a         3132 c         2758 g         4918 t
ORIGIN      
        1 ttataattct gcgatttggt ttaggtttac ttctgcaact gtgtcattac caaacataga
       61 gataatcatt ttcactttgt tattatcaat ttctgtaatc ttaccagtgt agtctgcaaa
      121 agcaccatca ataatacgta cagtttgacc aatctcaaca tcgaaatcaa attcttgaac
      181 agtttgtccc atagatacca aaatgtcacg aatttcttgt tccaataatg gagttggttt
      241 tgatctgttc ccgtgtgatc cgacaaatcc tgtaacattt ggtgtgtttc gaacaacaaa
      301 ccaagcttca tctgtcatga ccatttctac aagaacataa cctggaaagc gattttcttc
      361 tacttctttt ctctttccat ttttttcaac ttgcactgtt tgtgttggaa tttcaacgcg
      421 tagaatatta tccaacatat tgtaggtttg tgcacgttgt aatagatttt ctttcacctt
      481 attttcataa ccagaataag tttgtaaaac aaaccatcct ttatcaaaac tatccatgat
      541 atttcctttc ataaatagaa gatttctagt gtaattaact ccactaatct tctaaaaaat
      601 gttaataaat cgaatcaaac ctgaaacaat caactggtca aaaatgtaaa taattactac
      661 aaagaaagct gtgtattcca tgatagaacg aaaatctctc cagctttcct tgcgagttgg
      721 ccatgttgtg tctttaagaa gtctaaaaat atctccaata aaacgcatcg ctctctccta
      781 tctcgtttct ctgtgtgtag tgtacttgcc acaatgctta caaaatttat ttacttctag
      841 tcgtgtaggc ttggggtttc cgctgatctt gattgaatag tttctcgaac cacaaaccgc
      901 acaagctagg cttgcttttt ttagtgccat aacgcctcca tcttatccat tataacaaga
      961 aagctaggct ttgacaagca tcttagcgaa atagattgac tatcgaatcc catattgttt
     1021 gagccttttc cttaatcttc gcatctgaga tagcccggct agcctcatct actagacttt
     1081 gcgcacgccc tcgaatatca gacaaattat catctgtctg gctattatca ttggtttgta
     1141 cttgtctttt tgtattggct ggtgcaattc cattttgctt ataagcattt tcaaccgtaa
     1201 aggtacttcc tggcgtataa ggtaaaatgg tattggcaat gtttctaaag acatgagctg
     1261 caccgtttga agtagagcca gctagatagt gattttcatc agtggtcgga aagccaagcc
     1321 agtggctaat cactacatcc ggagtataac caattaccca ctggtcactt gtgtactccg
     1381 gattgaaaac tgcttcagtt gttccagttt tccctgccat gacatagtct gcaggcgatg
     1441 aactaatacc ggtaccgttg gtgaaagtcc ccaacatcat actggtcatc ttgtcagcta
     1501 cagacttatc aatcacccgt ttttgtgaat ttttatgatt cgcaataact tgtccactag
     1561 cattttcaat tctactaata aaatgagctt caggcattaa accttcattt gcaaaggcag
     1621 cgtatgcttg agccatttga agagggttgg tttcaacacc gcttcccaag gcgacaccaa
     1681 gaacacggtc gaccttttcc atgttgagtc cgaatttttc gcctgcctca aaagccttgt
     1741 cgacacccaa atcattaaca gtggcaacag caggtagatt aagcgattct gccaaggctt
     1801 gatacatagg aacttctcga ctcgttttga tccctgcata gttatcaacc ttatagctgt
     1861 catactgcat ggtatggtta tccaactgct tattcaaagc ccagcctgct tcaactgctg
     1921 gcgtataaac aactaaaggc ttaattgtag aaccaggact acgctttgat tgggttgcat
     1981 agttgaaatt ccggaatcca gttttatcat tgtcagcaac ttgaccgaca actccacgaa
     2041 ctccccctgt tttcggttcg agagctacac ttcctgattg agcaaacgtt ccatcctctg
     2101 ccctcggaaa tagcgatatg ttttcataaa caatctgcat atttgcttgg tagttttggt
     2161 ccagctctgt gtaaatgcgg tagccattat tgacaatctc ttcctctgtt agattatact
     2221 tggaaacagc ttcattaacc accgcatcaa aataagaggg gtaacggtaa tctgagattt
     2281 ttccttcata cttatcgtgc aattgcgaag tcatatcaac ttcagcagct tcggtttctt
     2341 ggtttttatc aatatatcct gctgcaacca tattctgcaa gacagtatcg cgccgattag
     2401 tagaatcttc tacagaattc aagggattat acagttccgg ccccttgagc atccctgcca
     2461 gagtcgcagc ttgatccaga ctcacttctg atgcagaaac tccaaagtat ttcttactcg
     2521 catcttctac accccacaca ccatttccaa aataagcgtt gttaaggtac atggttagaa
     2581 tttgctcctt actatatttt ttgcttaatt ctaaggcaag gaaaaattct ttcgcttttc
     2641 tctcaacagt ttgatcctgc gataaatagg cgtttttagc cagctgttgg gtaatggtag
     2701 agccaccacc tgaacgtcca gcagtgacaa tagccaagaa gaaacggcca tagttaatcc
     2761 cgtcattttt atagaaagaa cggtcttctg tcgcaataac agcattctgc aagtttttac
     2821 tgatgtcagt cagctcaaca taggttccct tttgaccaga caaggcacca gcctcttttt
     2881 cttcacggtc aaaaataaga gtccgagttt tcaaggcatt ttgcaaatca ttgacattgg
     2941 tcgacttggc tacagcaaac aaatagattc caactagcaa tcctgcactc aaacctagta
     3001 taaggataat ctttgttaga tgataacgac gccagaattt tcgaatcgga cctacttggg
     3061 ctaatttttt tcgatcacta cgagagcgac gtaagatagt agaatcagag tcctctagtt
     3121 cacttgtttc ttttttaaaa agagaaagaa atttctcaaa taatttatct aatttcatgc
     3181 gtttatttta tcatcttcat cataggaaga caagaattta gctatttcct atccaaatag
     3241 ggcttttttt gttacaatat ctgtatgcaa ttcacattta cattacccgc ctctctacct
     3301 caaatgacgg taaagcaatt acttgaggaa caactcctca tccctagaaa aatccgtcat
     3361 tttttgagaa tcaagaaaca tattttgata aatcaagaag aagtccactg gaacgaaatc
     3421 gtaaatcctg gagatgtttg ccagttgact tttgacgagg aagattattc ccaaaagacg
     3481 atcccttggg gcaacccaga cttagtgcag gaagtttatc aagatcaaca cttgattatt
     3541 gtaaacaaac cagaggggat gaaaacgcat ggtaatcaac caaacgaaat tgcccttctt
     3601 aaccatgtca gtacctatgt tggccaaacc tgctatgtcg ttcatcgtct ggacatggaa
     3661 accagtggct tagttctctt tgccaaaaat ccttttatcc tgcccattct caatcgctta
     3721 ttggagaaaa aagagatttc tagagaatat tgggctctag ttgatggaaa tatcaacaga
     3781 aaagaacttg ttttcagaga caaaattgga cgtgatcgcc atgatcgtag aaaaagaata
     3841 gttgatgcaa aaaatgggca atatgctgaa acgtatgtaa gcagattaaa gcaattctca
     3901 aacaagactt ccttggctca ttgcaagcta aagacagggc gaacccatca gattcgtgtg
     3961 cacctttcgc atcataactt ccctattttg ggcgaccctc tctataacag caattcaaag
     4021 acaagtcggc ttatgcttca tgcctttcga ctttccttta cccatccact tacattagaa
     4081 aaattaaact tcactgccct ctcaaatact tttgaaacag aattaaaaaa gaatggatga
     4141 ttgtgtcatc catttttcca tataagaaaa gcaagaccaa gaggccttgc tttttatcga
     4201 ttcaagaatt atttagcaat ttttgcgaag tattcaagag tacgaacaag ttgtgcagtg
     4261 tatgacattt cgttgtcgta ccatgataca actttaacca attgtttacc gtcaacgtca
     4321 agaactttag tttgagttgc gtcaaacaat gaaccgtaag acatacctac gatatctgaa
     4381 gatacgattg gatcttctgt gtaaccgtat gattcgtttg aagctgcttt catagctgcg
     4441 ttcacttcat caacagtaac gttcttttca agaactgcta ccaattcagt aactgatcca
     4501 gttggagttg gaacgcgttg tgcagatccg tcaagtttac cgttcaattc tgggattaca
     4561 agaccgatag ctttagcagc accagttgag ttaggaacga tgtttgcagc accagcgcga
     4621 gcacggcgaa ggtcaccacc acggtgtggt ccgtcaagga tcatttggtc accagtgtaa
     4681 gcgtggatag tagtcatcaa tccttcaaca acaccaaagt tatcttgaag agctttagcc
     4741 attggagcca agcagtttgt agtacatgaa gcacctgaga taactgtttc agtaccgtca
     4801 agaacgtcgt ggttagtgtt gaatacaact gttttaacgt cgtttccacc aggagcagtg
     4861 ataacaactt ttttagctcc acctttaagg tgtttttcag ctgcttcttt cttagcaaag
     4921 aaaccagtag cttcaagaac gatttctaca ccgtcagtag cccagtcgat ttgctctgga
     4981 tcacgttcag cagaaacttt aacgaattta ccgttaactt cgaatccacc ttctttaact
     5041 tcaacagtac cgtcgaaacg accttgagtt gtgtcgtatt tcaacaagtg tgcaagcata
     5101 actggatctg taaggtcgtt gatgcgtgta acttcaacac cttctacgtt ttggatacga
     5161 cggaaagcaa gacgaccgat acgtccgaaa ccgttaatac caactttaac taccattagt
     5221 gatttcctcc ttatgaaaat catgaaattt ttattgtgaa aagagtaact tgaatcacta
     5281 caaatcacct ttcaacaaac ctattatata actatttgag ttgaattgca agtacgggca
     5341 ttgtttttct ctgttagttt cttttttagg gacgataatc tagtaacacc cttgactatt
     5401 catagcgtag cgattctaca gggtccattt tactaatttt acgtgctggg aagtaggctg
     5461 atacatagcc aagcaagaga gcgaaaacta gagttcctaa aacagataac aaatttaatt
     5521 caaagacctt agcgatggat gggtaaaagt gacttacaat cgcattcgct aaacttccca
     5581 ccccttgtgc taccaaaaaa gccagtagca aggcgattcc tacaatccag atagcctcgt
     5641 aaataaaaat tcctttgaca tcacgattct gatagccaac tgccttcatg acacctattt
     5701 ccttggaacg ttgcatgata ttgatgtaaa taatgatacc aatcataacc gctgctacca
     5761 caatagcttg tgatgaaagc acaatcaata atccctgaat aacacgaata aaggtaatca
     5821 caatatcaag aactctctgt tgagaaagca cagtatactt cttatttttc tgtaattctt
     5881 ctgttactac ttttgtctgt gatggatctt tgagttccaa gataaaataa gatacagctt
     5941 tcgtaaatcc agcctctttt gaaatcgttt ccatttgatg aggcagcatg aaactgttgc
     6001 tgtcctccat gtcatcttca tcattgatta cacgtacaat cttcgtttga aattgagcaa
     6061 tcttactagt ttcggcagca ctttctacaa tgctggctga gactgatttg ccaataagat
     6121 cattagctgt caaatttttt cctgtctgtt cattccaatt ttttagtaaa ctgcttggaa
     6181 tcgttaatcc ctgttcattt gtatcagtat agagggagcc agccaacact ttgtccgtct
     6241 cattattact aacagagata cttgtatcat cataaagact cactacttga gcataagaag
     6301 gcatcgtttg actcagatcc atttcttgcc catctatagt aatatttgac atgttcatcc
     6361 caaaaggact ctccaaatat ttaatagctt ctttcccaac tgtatccgtg aactatagtc
     6421 aattgaaaca agagcaggat aaaaaagcct cgtaaaaggt attgcaactt ggtaatacct
     6481 ttttgaggtg ctttttgata tgagcccatg ttttctcaat aggattgtac tcaggtgagt
     6541 agggaggaag aggtaaaagt ttatgcccaa actcttcaca caagagttct aacttaccca
     6601 ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat gttggtaaga
     6661 gaaacttctg aaaccatgct tcaaaaaagt cgctcgtcat cgtctcttcg taagtcattg
     6721 gagcgattaa ctcaccattc atttgttaga cctgcaacca aagaaatcct ctgatatctt
     6781 cttcttaact gaccttttaa agagcgacca tattctcgat aaaaataagt atcaaatcct
     6841 gtttcgtcaa tctaaacagg tgctaggtgc tttaaactat taaaattctt aagaaataag
     6901 gctacttttt ctggctcttg ttcatagtag gtgtggttct ttttttcgag tgtagcccat
     6961 agctttgagc gcatagtgga tggtagttgg atgacagcca aattcagaag ctatttcagt
     7021 caaataagcg tctggattgt cagtaagata gtttttaagt ctatctctat caacctttct
     7081 tggttttgtt ccttttactt ggtggtttag ctctcctgtt ttctctttta gctttaacca
     7141 gccataaatg gtattacgtg agatttggaa aacgtgtgac gcttctgtta tactacctgt
     7201 tcgctcacaa taagagagaa cttttttacg aaaatctatt gaatatgcca taaaaagatt
     7261 ataccacatt gtgtactatt tttggttcat tttactatat ttgaagaggc gtttaaacta
     7321 tctgacataa aactcgttct agaggaaaga catcctttaa aaagttagtt tattttacaa
     7381 cttagacatc aaggtaggtt aaccccttca tggaaaaatc aagactctta gcactatggg
     7441 ttaaactacc actggagacg taatcaatcg ctaaaccacg aaaacggcta atagtggtca
     7501 tatcaatatt tccagaacat tcaatccgag aacgtcctgc aattagggta atggcctgtt
     7561 caatctgttc caatgacata ttatccaaca tgataatatc agcacccgcc gccgcagctt
     7621 cttcggcagc agcaaggctt tccacttcca cctcgaccat tttcacaaaa ggggcatagg
     7681 cacgcgcttg agcaattgcc ttttgaacac tacctactgc cgcaatgtga ttgtctttta
     7741 gcatgatagc atctgataaa ttaaagcgat gattatagcc accgccaact ctcacggcat
     7801 atttctcaaa aagacgtaaa ttaggagtag tttttcgagt atcaaatacc ttaatgcaat
     7861 catcgcctaa ggcttctaca taagcagctg tcatcgaagc aatccctgat aaatgttgta
     7921 aaaaattcaa ggcaacgcgt tcacatgtta agagacttct caccgagcct atgatttcta
     7981 aaaccaaatc gccactagtc aaacgatccc catccttaaa ttgatgagga ttctggaagg
     8041 tcacctcggc atcaaatagg gtaaaaaccc tttgaaaaac ggttagcccc gctaaaacac
     8101 cagcttcctt ggcaaaaagc gacaccttag cttggccatg atgatcaaaa atggcattgg
     8161 tactgtaatc ttcggaatga acatcttctc gcaaggctgc tttcaatgta tcatctattt
     8221 gaaaaggggt taaatcagtt gaaatgattg acatcactaa gtcctctatt tttaatatca
     8281 cttgtaagca ttagaggcaa tcactattaa cttccatagg aaatcacaag cctgaatacc
     8341 tcatttttaa ttctaacaag tgtcaataca attgtcaaga caattgtatt tttttgtgta
     8401 taatagtcaa gtaccaatag gaaacaggtg gtcttttgag cgccaaaatt gccaacctat
     8461 ttccatattc taactgaaag gacaattcaa tgattcattt aataatgatt agcgccattg
     8521 ctctagccat tggaattggt taccgcacca aaatcaatat tggcctgctg gctattgctt
     8581 tttcttacct catcgcaacc actctcatgg gattaagccc caaagaactt cttcattttt
     8641 ggccaacctc actctttttt accattttta gcgtctctct cttttataac tttgcaataa
     8701 ctaacggtac tcttgatgtt ttggctcaac acattctcta ccgcacacgc acctacccta
     8761 acgccctcta catgatttta tacctgatgg caaccctttt gtctgcttta ggtgctggat
     8821 ttttcactac tatggccgtt tgctgtcctc tagcgattac cctctgtcaa aaagcggaca
     8881 aacacccttt gattggagct caagccgtca attggggagc ttcaggaggg gctaatttga
     8941 taaccagtag ctcaggcatt gtctttcaag gcctgtttaa gcaaatggga tgggaagagc
     9001 aagctttttc acttggcaat catatcttta tcgtcagcat tatctaccca ctcatcgtct
     9061 tgcttttatt atcctgttac agtcactata gtaagggaaa aacaaactca tccttgacta
     9121 ttgaccaacc accactcctc agcaaggttc aaagacaaac caccttgctc atgatcagca
     9181 gcatggtttt ggtttggctt tttcccttgt tgcatctcat tttcccaaac atcgcctgga
     9241 tagctactta tcaaaaaaca tttgatattg gctttgtctc aatactcatg gtctgcctcg
     9301 ccttaaggct caaattaggg aagcaagaag ccattttagc taaggttccc tgggctacaa
     9361 ttatcatgct ctgcggcatg agcttactaa tgtctctagc ggtcaagtca ggtttagtca
     9421 cactgatagg gcacctcatg acaacatcca ttcctcattt ctggttacct ctgttctttt
     9481 gtgtgatagc cggagtgatg tcactcttta gttccaccct atccgttgta gctccagccc
     9541 tctttcccat cattgctatc atcagtgctc aaaatcccca gattgatatt cacttactca
     9601 caacagccac cgttattggc gctctatcta ctaatatctc acccttttca tcagctggtt
     9661 ctctcattca actctcactt cccaatatag aggaacgtgg ccttgccttc aaaaagcaaa
     9721 ttattctggg tgtccccatc agcttaagtt tgggactctt gaccacctgg attctcatcc
     9781 ttctagcttc cttaagttag atttattatc taacttaagg gtggacttgg tataataaag
     9841 tagacacaaa attaagtgga aacgaggaaa agtcattatg ccaagaaaaa cctttgataa
     9901 agccttcaaa ctctctgctg taaacctcat cctgtaaaaa tgattagttc aactttaaaa
     9961 attcatccca atagtcttta tcgatggatt caagaatatg aaaaatatga agaaagtgcg
    10021 ttcccaggac atgggagcgc acttcgtcat actcaatttg agatgtagtg aaatgaaata
    10081 agaacaggac aaatagatca ggatagtcaa atcgatttct aacaatattt tagaagtaga
    10141 tgtgtactat tctagtttca atctactata gtaaagttga ctttcctgta ccatttttac
    10201 cagtaattaa tgtcacgcct gaactcgaag tatcaaaaga aatattatca aacaatatac
    10261 gatgatccac cctatacgaa atattttcta ctttcatttt ttctcctttt gaactaatag
    10321 caaaagaaac agttctgttt tcatactctt tccccttcat ctatattatt cgtaatgaaa
    10381 aataaaaaat aaaatttttt taaatgatta tgattcagaa tttatttaat atattaaaag
    10441 aagatatgaa caaataaatt gggagattga aattcatttc tagcaatttt ttagaagtca
    10501 cagtctacta ttctaacctc agtatactat atgtgttaca agaaaagact caaaaacttc
    10561 tcgtcagtgt aagaatattt gaaacactat ttaaaactaa ataactataa gaagtagatc
    10621 aggtgaacaa tttcagtacc tactctataa gctatacgaa gatatttttc aacatgatgg
    10681 ataaaacgat cactctttta aagctatctt atttagaaaa gagaaaccat ttaagcatag
    10741 atgggacctt cttgccctgt tttaaatttt tcttaaacta gagtctgtaa aagattggct
    10801 tcattttcac attttctcct aggaggaatg tcgtaatgca aaagaattaa attcaaataa
    10861 atcatagcga tgacgactaa tcgagtactc aaacggagtt ccgttatcca aataagccac
    10921 ttgttctact tcaaataccg gttccgttgg aaggagctgc aagtaatgtt gctcattttc
    10981 tgaactagaa gaagctcgca agatttttgt agcactggca atatgcaatc ctaactttcc
    11041 ttcaatgtaa ttgtaaatcg atttttgtaa aatatcttca gtaatacctg gaataacatc
    11101 ggtactcata taagtttgtt ccagaacata aggtttaccg tcaataatac gcaggcggta
    11161 aatattataa actggactct gcaaagcgac ctgtagtttt tctgctaaaa attcatttgc
    11221 aaattctaat ttgaagtgaa taatcctcga gtcaattgta gaatgagcat cttcagatat
    11281 ttttgtcagt ccccggatat ctctttctgg aacgattaat tttctttttg agctgccacg
    11341 agagagaaca aaggttccct gcccacgttt tctaaaaatt aagccctcag aaactaacaa
    11401 gtctaaagct tttttgatcg tcattcgact acaggcaaac tgtttagcta atgtcatttc
    11461 atcaggcaat tgttcgttca tggtatattt attacaaaga atcttttcac gaatctcatt
    11521 gtaaataaat aaatattttg tactcattta atctggttct ctctataata ttctaatagt
    11581 agtataacaa agttcaagaa atgaggcaaa cacaagatat gtatcaacaa tttttaaaaa
    11641 tgtctagaca aattttaaaa ttatgctata ctttatgtat agaataatag aaaggaggtt
    11701 gagcatgaaa aaaaagttag tatttcctaa tctgttttgg tggggagctg cttctagcgg
    11761 acctcagaca gaaggtcaat atggaaaagt acatgaaaat gtgatggact actggttcaa
    11821 aacgcatcca gaagattttt tcgataatgt cggacctctt gtagccagta acttttttca
    11881 tacttacacc gaagatttcc acttgatgaa ggaaattgga gttaattctt tccgcacttc
    11941 catccaatgg agtcgactca tcaagaattt agagacaggt gagcctgatc caaaaggtat
    12001 tgctttctac aatgccatca ttgaagaagc taaaaagaac cagatggatc ttgtgatgaa
    12061 tttacatcat tttgatttac cagtggaact tcttcaaaaa tacggtggtt gggaaagcaa
    12121 acatgtagtg gagttattcg tgaagtttgc caagactgct ttcacatgct ttggagataa
    12181 ggttcattac tggacaactt tcaatgagcc aatggtcatt ccagaagcag gatacttata
    12241 tgctttccat tatccaaatc taaaaggaaa gggaaaagag gccgtacaag tcatctataa
    12301 tctaaacctt gctagtgcaa aagtgattca actatatcgc tcattaggac ttgatggaaa
    12361 gattgggatt attttaaact tgacacctgc ttatccaaga agtaattctc cagaagactt
    12421 agaagcaagt cgatttacag aagacttctt taacaaagtc ttcttgaatc cagctgttaa
    12481 aggaactttc ccagaaagat tggtaaaaca gctagagaga gatggcgtgt tatggagtca
    12541 taccgaaaaa gagcttcaac tgatgaaatc aaatacggtt gattttcttg gagtaaacta
    12601 ctaccatcca aaacgtgttc aagcacaagc aaatcctgag gaatatcaga cgccctggat
    12661 gccagaccaa tacttcaaag agtatgaatg gccggagcgt cgcatgaatc catatcgtgg
    12721 ttgggaaatt tttccgaaag ccatttatga tattgctatg attgtgaagg aagaatatga
    12781 taatattcca tggtttatca gtgaaaacgg aatgggtgtt gaaaacgaag cacggtttat
    12841 cgatgaaaat ggagttatcg atgacgtgta tcgtattgaa ttttatgaag aacatttaag
    12901 atggctacat aaagccattg aagagggaag tcactgtttt ggataccacg cttggaccgc
    12961 atttgattgc tggtcttgga ataatgcata taagaatcgt tacggattta tctccgttga
    13021 tttagaaacg caaaagagaa ccatcaagag ctcaggaaga tggtatcgca aagtaagtga
    13081 caataacggt tttgaagtag aaattgagga gtaaagagag gagatattca gatgaaaaac
    13141 tcaaaattta tagatcaatt tgccaccttt gctggtaaac tagggaacca aattcattta
    13201 aaaaccctaa gagatgcatt cgtaacagta atgccattat atattttggc aggtttaatc
    13261 gttcttttga acaacacggt atttaagtgg attttccaag gggatacatt aacaaaattc
    13321 caatattggg gaataacaat tgcaaacggt actttaagta tttcaggtat gattattgct
    13381 gtaatggttg gttatttctt agctaaaaac agagatttcg aaaacccgtt agcagcatca
    13441 atgctatcat tagtttcttt aattgtgatg atgccaaata cagtttctgt agttcctgac
    13501 ggagcaaaag atgcggtaaa catttcaggt gttctttcat tcaacaacac aggtacaggc
    13561 gcaatgttcg ccggggttat cgtagcgatt attgcaacag aattattcat tgaattatca
    13621 aacgttaaag ctttacaaat gaaccttggt gaaaatattc caccagctgt tagtagatca
    13681 tttagcgtat tacttccagt catgaccgtc atctccttat ttggggttgt ttcagcatta
    13741 ttattcaata taactggaat gaacttaatc tcaatcatta caatctttat tcaagaacca
    13801 attcgtcata ttggtacaag cttaatcggg gtcattatta tttactcttt aggaaatatg
    13861 ttatggctat ttggtattca ccaagcagtt atttacagtg ccatcctaga accattacta
    13921 ttaattaaca ttactgaaaa catcactgca gcaaataatg gacaagccat tccacacatc
    13981 atcaacttat cacaaataca aacattcgct ttaatgggtg gtagtggatc tacattatgt
    14041 ttattaatag caacattctt agtgagtcgc aatgctgttt ctaaaaacgt ggctaaatta
    14101 tcttttggac ctggtatctt caatatcaat gaaccagtat tattcggtta cccaatcgtt
    14161 tataacattt cattagctat tccatttatc acagttccag tccttggtat tttaatcagc
    14221 tacttagcaa cagttacagg attcatgagt cctgcattta tacaagttcc ttggactaca
    14281 ccagtattct taaatgcatg gttagcaaca gcaggggacg tgagagcagt tctagttcaa
    14341 ttcatcatct ttgcacttgg agttcttcta tacattccat ttatcaaagt taatgacaaa
    14401 gttgttgaac aagaaatgga aggttaagat tatgaaacaa attttattag tatgtaatgc
    14461 gggaatgtcg acaagtatgc ttgttaaaaa aatgcaacaa agtgcgactg aacgtgggat
    14521 tgaaatttct atccaagcaa aatcaatgac agaagctaaa aagaatatcc atgaagcaga
    14581 tgtcattcta attgggccac aaattcgtta tgagttactt gctgtgaaag aaattgcagg
    14641 aaatacccct gtagatacca ttgatatgcg ggattacgga atgatgaatg gagcaaaagt
    14701 tctggaacaa gcacttgcat ggataggaga aataagatga cagaagaaat ggaatatatc
    14761 tgttttcagc tcattgccaa tagtggagca gccaaatcat cctttattga agccatccaa
    14821 ctagctaagg cgggaaattt aaaagaagcg aaaattaaag ttgaagaagc ggaagactcc
    14881 ttagtagaag cgcacaagat tcactctaat ctcatacaaa aagaagctac tggagaaaaa
    14941 ataggattct ccttgctatt tatgcatgca gaagaccaaa tggcttcaac agagattatt
    15001 cagttgctat ctaaagaatt catcgatctc tatcaaaata aataggaaca ctgtcattcc
    15061 catctgtctt tattaatgac gactacattg taggaacctc caaaagttgg acaaaatgat
    15121 tgaaaggatt ggatcctgca ttacacaaga tccaatcctt ttcttttact ctagttttta
    15181 taatatgttg aatctagaat agtccactgt agtttctaaa aaattgctgg aaatggatgt
    15241 taagctccaa tttatttgtt tatatcttat ttcagtttac tatactagct tattattcta
    15301 gtgaaaaatt gaatgagcca ctatttattt aatatgtatg atgagggaat gactcaaaaa
    15361 cttcttgtcg atataagaat atctgagata gtattttaaa acgaaaggac tataaaagct
    15421 catttccttc gcacttattt tatagagatc tatcattata ctctttagaa atcaaaaagc
    15481 aacacacctt gtcatcgttt tatcgtaaat ctgttaatga gggggctagt cttatctgca
    15541 atctcaaatc agtgttttga gctgaatggc actcgttttc tagtttgctc tttgatttta
    15601 attgggcctt agtaaatact actcttaaat taaactatag tgaattgaaa taagatgtga
    15661 acaactctat c
//
LOCUS       DAVKZI010000043        15090 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKZI010000043 DAVKZI010000000
VERSION     DAVKZI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.044"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..407
                     /locus_tag="VXB18_001716"
     CDS             <1..407
                     /locus_tag="VXB18_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0382885.1"
                     /translation="DQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPNV
                     AIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGKEVEVSLLFFIINNSSSSQTNILAQ
                     LMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            445..747
                     /locus_tag="VXB18_001717"
     CDS             445..747
                     /locus_tag="VXB18_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0382886.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            755..1559
                     /locus_tag="VXB18_001718"
     CDS             join(755..1123,1125..1559)
                     /locus_tag="VXB18_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0382887.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            1608..2072
                     /locus_tag="VXB18_001719"
     CDS             1608..2072
                     /locus_tag="VXB18_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0382888.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2230..2655
                     /gene="lacA"
                     /locus_tag="VXB18_001720"
     CDS             2230..2655
                     /gene="lacA"
                     /locus_tag="VXB18_001720"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0382889.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2686..3201
                     /gene="lacB"
                     /locus_tag="VXB18_001721"
     CDS             2686..3201
                     /gene="lacB"
                     /locus_tag="VXB18_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0382890.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3212..4141
                     /locus_tag="VXB18_001722"
     CDS             3212..4141
                     /locus_tag="VXB18_001722"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0382891.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            4143..5123
                     /gene="lacD"
                     /locus_tag="VXB18_001723"
     CDS             4143..5123
                     /gene="lacD"
                     /locus_tag="VXB18_001723"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0382892.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5357..6193
                     /locus_tag="VXB18_001724"
     CDS             5357..6193
                     /locus_tag="VXB18_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0382893.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6229..6546
                     /locus_tag="VXB18_001725"
     CDS             6229..6546
                     /locus_tag="VXB18_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0382894.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6546..8237
                     /locus_tag="VXB18_001726"
     CDS             6546..8237
                     /locus_tag="VXB18_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0382895.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDVAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8452..9858
                     /gene="lacG"
                     /locus_tag="VXB18_001727"
     CDS             8452..9858
                     /gene="lacG"
                     /locus_tag="VXB18_001727"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0382896.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9901..10110
                     /locus_tag="VXB18_001728"
     CDS             9901..10110
                     /locus_tag="VXB18_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0382897.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEE"
     gene            complement(10437..11198)
                     /locus_tag="VXB18_001729"
     CDS             complement(10437..11198)
                     /locus_tag="VXB18_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0382898.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11380..12342)
                     /gene="nrdF"
                     /locus_tag="VXB18_001730"
     CDS             complement(11380..12342)
                     /gene="nrdF"
                     /locus_tag="VXB18_001730"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0382899.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSADD
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEVMQDDDYNYGLD"
     gene            complement(12530..14689)
                     /gene="nrdE"
                     /locus_tag="VXB18_001731"
     CDS             complement(12530..14689)
                     /gene="nrdE"
                     /locus_tag="VXB18_001731"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0382900.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14770..14988)
                     /gene="nrdH"
                     /locus_tag="VXB18_001732"
     CDS             complement(14770..14988)
                     /gene="nrdH"
                     /locus_tag="VXB18_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0382901.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
BASE COUNT         4674 a         2715 c         3090 g         4611 t
ORIGIN      
        1 ttgatcaggt agcaagcttg ttggaagaac gagaaattgt cactccaact tatcgtgaag
       61 ccttgatcac gcgtgaaaag tcatttccaa ctggtttaga tatggaattt ctaggaaagg
      121 acttgccaaa tgtagcgatt cctcacacag atattgttca taatctagct gaaaaagtgg
      181 tggttgttcg attagaaaaa ccagtaactt ttcacaatat gattgcgcca ggtaaggaag
      241 tagaagtatc cctactcttc tttatcatta acaattcaag ttcaagtcaa acaaatattc
      301 tggctcagtt gatggacttt ttcacaggaa atggacatct tgaagaccta tcaaaaattt
      361 ccgaaccaga aaaactttat gcttacattg ctgaagcaac cgcttaatct tgtctattaa
      421 aaaataaaat cggaggaaat ctaaatgatt aaaattcttg ctgcctgcgg tgcaggtgtt
      481 aactcaagtc accaaattaa aagtgctcta gaagaagaac tttcaaaccg tggttatgat
      541 gttcactgtg atgcagttat ggtgaaagat gtaaacgaag accttatgaa aggttacgat
      601 atctttacac caatcgctgc aacagacctt ggttttgaac caggtatccc agttatcgaa
      661 gctgggccaa tcttattctg tatcccagca atgagcgttc cagtatttga caatattaga
      721 cttcctgcga aacaaaatat ggtatagtag ttccatgaat tatgaagcaa gtaaacaact
      781 aactgatgca cgatttaagc gtcttgttgg tgttcaacgc acgacttttg aagagatatt
      841 agctgtatta aaaacagctt atcaacttaa acacgcaaaa ggtggacgaa aacctaaatt
      901 aagcctagaa gactttctta tggccactct tcaatatgtg cgagaatatc gaacttatga
      961 agaaattgcg gctgattttg gtatccacga aagcaactta atccgtcgga gccaatgggt
     1021 tgaagtaact cttgttcaaa gtggtgttac gatttcaaga actcctctca gttctgagga
     1081 cacggtaatg attgatgcga cggaagtaca aatcaatcgc cctaaaaaaa caattagcga
     1141 attattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc acaagtcaag
     1201 ggagaattgt ttctttggat atcgctgtga actattgtca tgatatgaag ttgttcaaaa
     1261 tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt tatcaagggc
     1321 tcatgaagat atatcctcaa gcacaaattc cacgtaaatc cagcaaactc aagccgctaa
     1381 tagctgaaga taaagcctat aaccatgcgc tatctaagga tagaagcaag gttgagaaca
     1441 tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat catcgtaaac
     1501 gcttcggatt acgaatgaat ttgagtgctg gtattatcaa tcatgaacta ggattctagt
     1561 tttgcaggaa gtctaataaa gaaactagca aggtcaggcc ttactttatt ggtggacatc
     1621 caggatttaa ttgtcttcta cttgatgatg aagtctatga agattattat ctagagtttg
     1681 agaaagaaga gatttgctct gttccacgtc ctttcccaga aacaggtatg ttggatttcc
     1741 aagatagaag tccatggcta gagggacaaa aagaaataga tcttagttat gatcttttca
     1801 gcacagatgc agtgactttg gatgaattgc aatctcgaac aattgccctt cgttctctta
     1861 aacatgataa gggattgaaa gtgcattttg cagaatttcc aaacctcatc atctggtcaa
     1921 ctttgaacaa gggacctttc attacctttg aaccatggtc tggcttgtca acattccttg
     1981 aagaaggaga tcatttagaa gataagaaga atgtttgtct cttagaagcc aatcaggttg
     2041 aagaattagg gtttgagata gaagttttat aaaaaaagta aaaaataaat aacaaaaaca
     2101 aacacaaact gttgacttct tcaaacaata gtagtatatt atgtttgtga ggactaattg
     2161 actgtttttt aaagacagcc aatacactgc tggaatccag catagaaaaa ataaaaagga
     2221 gtatacaata tgtctattgt tatcggtgca gatgctgcag gtttgagatt gaaagaagtt
     2281 gtgaaagact tcttagaaaa agaaaacttc caccttgtgg atgttacagc tgaaggtcaa
     2341 gactttgttg atgtgactct cgctgttgct gcagaagtaa acaaagaaga acaaaacctt
     2401 ggtatcgtga ttgatgctta tggagctggt ccatttatgg ttgcaactaa gatcaaagga
     2461 atggttgctg cagaagtatc tgacgaacgt tcagcttata tgactcgtgg ccacaacaac
     2521 tcacgtatga tcactatggg ggcacaactt gttggtgatg aattggctaa aaacatcgct
     2581 aaaggatttg ttaatggtaa atacgacggt ggtcgtcacc aaatccgggt tgacatgttg
     2641 aacaaaatgt gctaattaga ttatagtaag aaaggtaagt taaaaatgag aattgcaatt
     2701 ggatgtgacc acatcgtaac agatgaaaaa atggcggttt cagaattttt gaaatcaaaa
     2761 ggatatgaag tcattgactt tggtacctat gaccatacac gtactcacta cccaatcttt
     2821 ggtaaaaaag taggggaagc agtaactagt ggtcaagctg atctcggggt atgtatctgt
     2881 ggtactggtg ttggtatcaa caacgctgta aataaagttc caggtgttcg ttctgccttg
     2941 gttcgtgata tgacaacagc cctttatgct aaagaacaat tgaacgccaa cgttatcggt
     3001 tttggtggta agattactgg tgaattgctt atgtgtgata tcatcgaagc tttcattcat
     3061 gctgaataca aaccatctga agaaaacaaa aaattgattg cgaaaattga acaccttgaa
     3121 agtcacaatg ctcaacaaac agacgcaaac ttcttcactg aattccttga aaaatgggat
     3181 cgtggagaat accacgacta agaggtaacc tatgatttta acagttacaa tgaacccatc
     3241 cattgatatt tcctatccct tggatgagtt gaagattgat actgtcaatc gtgtggtgga
     3301 tgtaaccaaa acggctggtg gtaagggact caatgttacc cgagtacttt cagaatttgg
     3361 cgattctgtt cttgctactg gtttagtggg tggcaaactt ggtgagtttt tggttgaaca
     3421 tatcgataat caagtaaaga aagatttctt ctcaattcag ggagaaactc gtaactgtat
     3481 cgctattctc cacggagaca accaaacaga agttcttgaa aaaggtcctg aagtattgga
     3541 acaggaaggt caagactttt tggaacattt caaaaaactc ttggagtcag ttgaagtagt
     3601 ggccatctca ggtagtctgc cagctggcct tccagttgat tactgtgcga gcttggtaga
     3661 acttgctaat caagctggca agcctgtagt cttggactgc tcaggtgcag cacttcaggc
     3721 tgttcttgaa tcaccccata aaccaacagt catcaaacca aataatgaag aattgtctca
     3781 gcttcttgga agagaagttt ctgaggattt ggatgaatta aaagaagtac ttcaagaacc
     3841 tttgtttgca gggattgaat ggattatcgt ttcacttggt gccaacggta cttttaccaa
     3901 acatggtgac actttctaca aggtagatat tcctagaatt caggtggtaa atcctgttgg
     3961 atctggagac tctactgtgg caggaatttc ttcaggactt cttcacaaag aatcggatgc
     4021 agaattactc atcaaggcaa atgtccttgg tatgctcaat gctcaagaaa aaatgactgg
     4081 tcatgtcaac atggccaact atcaagctct atatgatcaa ttaatagtaa aagaggtata
     4141 aaatggcttt aacagaacaa aaacgtgtac gcttagaaaa actttctgat gaaaatggta
     4201 tcatctcagc tcttgcattt gaccaacgtg gtgctttgaa acgcctcatg gctcaacacc
     4261 aaacagaaga accaactgtg gcccaaatgg aagaacttaa agttttggta gcagatgaat
     4321 tgactaaata cgcttcatct atgcttcttg accctgagta tggacttcca gcaactaaag
     4381 ctcttgatga aaaagctggt cttctccttg cttatgaaaa aacaggttat gacacaacaa
     4441 gcacaaaacg cttgccagac tgcttggatg tttggtctgc aaaacgtatt aaagaagaag
     4501 gtgcagatgc agttaaattc ttgctttact atgatgtaga tagctcagac gaactcaatc
     4561 aagaaaaaca agcctacatc gaacgcatcg gttctgagtg tgtggctgaa gatatcccat
     4621 tcttccttga aatccttgct tacgatgaaa aaattgcaga cgcaggttct gtagaatacg
     4681 ctaaagtaaa accacacaaa gttatcggtg ctatgaaagt cttttcagac ccacgcttta
     4741 acattgatgt cttgaaagtt gaagttcctg ttaacattaa atatgttgaa ggcttcgctg
     4801 agggtgaagt ggtttacaca cgtgaagaag cagcagcctt cttcaaagcg caagatgaag
     4861 caacgaactt gccatacatc tacttgagtg ctggtgtatc agctaaactc ttccaagata
     4921 ctcttgtatt tgctcatgaa tcaggtgcaa actttaacgg agttctttgt ggccgtgcta
     4981 catgggcagg gtcagttgaa gcttacatca aagatggtga agcagcagct cgcgaatggc
     5041 ttcgcacaac tggatttgaa aacattgatg agctcaataa agttcttcaa acaacagcga
     5101 cttcatggaa agaacgtgtg taagaaagtc ctcctagttt aggaacatga atctaaaaaa
     5161 atttaaaaaa agttgtatgt aaaggtttac aaaataactt acttgtgcta tacttaaatc
     5221 acaagttaat acaaggtgag tgttactaag taatattagg catgatcaca ggtgaattag
     5281 aaatcagctg attttctagt tcatttgtgg tcattttttg tactcatata cctttaaaat
     5341 ataaaaggag gttgacatgt atcgaattct aaatccaatg aatcacaatg tctcgcttgt
     5401 cagaaatgat aagggagaag aggtgattgt aattggtaag gggattgcat tcggaaagaa
     5461 gaagggggat ttgattgctg aaaatcaggt tgagaaaatc tttcggatga agaccgaaga
     5521 gtccagagaa aactttatgg ctcttctcaa agatgttccg cttgatttta tcacagtgac
     5581 ctatgaaatc attgataagc tatcaaagaa atatcattat ccgattcaag agtatctcta
     5641 tgtaaccttg acagatcata tttactgttc ttatcaagct ctaactcaag gaaggtacaa
     5701 ggatagtaat ctgccagata tttccgctaa gtatcctgtc gcttttcaaa tcgcaaatga
     5761 agcttttgaa atttaccgtc agaagctagc agatcatttt cctgaggacg aaattattcg
     5821 gattgcttat catttcatta atgctgaagg tgaaaatgaa gtggaacttg tggagtcgat
     5881 tgataagagg aaagaaattc tcaggaatgt tgaagaagtt ttaacggact atgcaattca
     5941 acgaactaaa aagaataacc atttctatga tcgctttatg atccatttga attatttctt
     6001 ggattattta gacagatcta gagatgataa ccaatcactt ctggatatgg aagatcatat
     6061 taaacaatcc tatccaaaag ccttcgagat tggttccaag atctatgatg tgattacgca
     6121 acatacgggt cttgatttgt ataaaagtga acgagtttat ctagttctac atatccaacg
     6181 tttattgtca taaaaattta tttaaaacta tataaggaga attctatcat gaatagagaa
     6241 gaagtaacat tgttaggttt tgaaatcgta gcctatgctg gcgatgctcg ttcaaaacta
     6301 ttggaagcct tgaaggctgc tgaagctggt gattttgaaa aagcggacgc tctggtagag
     6361 gaagctggta gctgtattgc agaggctcac cacgcgcaaa caagtctatt gactaaggaa
     6421 gcttctggtg aggacttagc gtatagtgtg accatgatgc atggtcaaga tcacttgatg
     6481 acaactatct tgttaaaaga cctaatgcac catttaattg aactttacaa gagaggagtt
     6541 aaataatgaa taaactaatt gcatttatcg agaaaggaaa gcctttcttt gaaaaactat
     6601 ctcgtaatat ctatcttcgt gctattcgtg atggtttcat tgcaggtatg cctgttattc
     6661 tcttctcaag tatctttatc ttgattgcct ttgtaccaaa ctcatggggc tttaaatggt
     6721 ctgatgaagt tgtagccttt ctgatgaaac cttatagcta ttctatgggt attctggctc
     6781 tcttggtagc tggtacaaca gctaagtcat tgactgactc agtaaaccgg agcatggaaa
     6841 aaaccaatca aatcaactat atgtcaacat tgttggcagc aattgttggt ttgttgatgt
     6901 tggcagctga tcctatcgaa agtggtctag ctactggatt cttgggaaca aaaggtttgc
     6961 tttcagcctt ccttgctgcc ttcgttactg tagccatcta taaggtctgt gttaagaaca
     7021 acgtcactat tcgtatgcct gacgaagttc caccaaatat ctcacaagtc tttaaagatg
     7081 tgattccatt cactctatca gtggtttctc tttatgctct tgatttacta gctcgtcatt
     7141 ttgttggttc tagtgtggca gaatcaatcg gtaaattctt cgcaccactc ttctcagcag
     7201 cagacggata ccttggtatt accattatct ttggtgcctt tgccttcttc tggtttgttg
     7261 ggattcatgg tccatctatc gttgaacctg ctatcgcagc gattacctat gcaaatgctg
     7321 aagtcaactt gaaccttctc caacaaggga tgcatgcaga caagattctt acttctggta
     7381 cacaaatgtt tatcgttacc atgggtggta caggtgcgac attggtcgtt ccatttatgt
     7441 tcatgtggtt gacaaaatcg aaacgtaacc gtgcaatcgg acgtgcttca gtagttccta
     7501 ccttcttcgg tgtaaatgaa ccaatcttgt ttggtgcacc tcttgttttg aatccaatct
     7561 tcttcattcc atttatcttt gctccaattg caaacgtatg gattttcaaa ttctttattg
     7621 aaactcttgg aatgaactca ttcactgcta atctaccatg gacaactcca gctccactag
     7681 gtctagttct tggaactaac ttccaagtgc tatcattcat tcttgctgcc cttctaattg
     7741 tggttgacgt agttatttat tacccattcc ttaaagtcta tgatgaacaa attcttgaag
     7801 aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa agttgctgca aacttcaaca
     7861 ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga tgtagcacaa aataccatca
     7921 ctgaagaaac aaatgtcctc gttctctgtg ctggtggagg tacaagtgga ctccttgcaa
     7981 atgctttgaa taaggcagca gcagaataca atgtccctgt gaaagcagca gcaggcggct
     8041 atggtgctca ccgtgaaatg ttgccagagt ttgatttggt tatccttgct cctcaagttg
     8101 cttcaaactt tgaagatatg aaggcagaaa cagataagct cggtattaaa cttgctaaga
     8161 cagaaggcgc tcaatacatc aaattaactc gtgatggaaa aggtgcccta gcattcgtac
     8221 aagagcaatt cgattaaggc taggaactgt gaaacagtct cccatcgtta cggaaatcgc
     8281 tatggcgaat ttcctaatcg ccttattaat tcgtcggtaa aaagatatcg tttttacctc
     8341 ctcatgtcac aattcagtga cttggtacaa gaagtgagat ggagaagcat ggctcactga
     8401 ctcctctcct ctcactttta ctttatttaa atcaagaaat aggtgaaaaa aatgacaaaa
     8461 acacttccaa aagactttat tttcggtggc gcaacagctg cttatcaagc agaaggtgct
     8521 acacatactg atggaaaagg accagttgct tgggataaat atcttgagga taactactgg
     8581 tacactgccg aaccagctag tgatttttac aatcgatatc cagttgacct caagctagca
     8641 gaagagtatg gtgtcaatgg tattcgaatt tctattgctt ggtcacgtat tttcccgact
     8701 ggttacggcc aagtaaatgt taaaggtgtt gagttttatc ataatttatt tgcagagtgt
     8761 cacaaacgtc atgttgagcc ctttgtaact cttcatcact ttgacacgcc agaagctctc
     8821 cactcaaatg gagacttctt aaaccgtgaa aatatcgaac attttgtaga ctacgctgcc
     8881 ttctgttttg aagaatttcc agaagtaaac tattggacaa cctttaatga aattggacca
     8941 atcggtgatg gtcaatattt ggttgggaaa ttccctccag gtatccagta cgaccttgcc
     9001 aaagtctttc aatcacacca caatatgatg gtgtctcatg cgcgtgcagt caagctatat
     9061 aaagataaag gctataaagg tgaaattggt gttgttcacg ctctgccaac caagtatcct
     9121 ttggatccta aaaatccagc agatgttcgt gcagctgagt tggaagatat catccacaat
     9181 aaattcatct tagacgcaac ttatctaggt cgctattcag ctgaaaccat ggaaggtgtc
     9241 aaccatatct tatcagtcaa tggtggtagt ttggatcttc gtgaagaaga ttttacagca
     9301 ttagaagctg caaaagactt gaatgatttc ctaggaatca actactatat gagtgactgg
     9361 atggaagcct ttgatggaga aactgaaatt atccataatg gtaaaggtga aaaaggaagc
     9421 tctaagtatc aaatcaaagg tgttggtcgt cgtgtagctc ctgactatgt accacgcacg
     9481 gattgggatt ggattatcta ccctcaaggt ttgtatgacc aaatcatgcg tgtgaagaaa
     9541 gattatccta actacaagaa gatttacatc actgaaaatg gtctcggcta taaagatgag
     9601 ttcgttgata acactgttta cgatgatggt cgtattgatt acgtgaaaca acacttggag
     9661 atcttgtctg atgcgattgc agatggagct aatgtaaaag gttacttcat ttggtcatta
     9721 atggatgtct tctcatggtc aaacggttat gagaaacgtt atggtctctt ctacgtagat
     9781 tttgaaactc aagaacgtta tcctaagaaa tcagctcact ggtacaagaa agtagcggaa
     9841 actcagatta tagactagta gaattagtca ttagatatag aattttagtg agtcaaaaag
     9901 atgttcaaag attttatcca atctatttat gaaaaagttt atattataaa tttcgaaaaa
     9961 tgctctcaaa taccgtgttt gacgagtgaa gaattgaaaa gtcttggaaa atggtatgtc
    10021 tcgactggta aagaatggat ttgtcattca gatgatgagc tggaagaatt taaaaatcta
    10081 tttttaaatt ttatcaatcc tgaagaatag gatactatct cctttgattc agattttatg
    10141 ccgtttcaac aatcgtaacc aatttctcaa aaaagttaaa tcttatattt agtactctgc
    10201 aaaactctta tctgatcacg ttgcttatac tcaatgaaaa tcaaagagca actttaaact
    10261 aggaagcgag tcgcagattt ctcaatgcat agctttgagg aattgggcaa aaagtctttg
    10321 atatagaaaa aagcatagta tcaggtgttg aaacacctga tactatgctt tttattgtgg
    10381 gaagatttac tttttttctt ctgaaattga gttgttaccc aggctctttc agtttattaa
    10441 ggcttgatga ctttaatgtg tttagatagc ttaaaaagga ttgaatcact tagtttagaa
    10501 tctgaaacaa tagtatcaag atttgataca ttataaaaag tataaaaatc aaacttattg
    10561 aacttactat gatctgcgag taaatatttt ttattagaat tatttaaagc gatgcgttga
    10621 gcctctccct cttcctcgct aaaagtagct agagctccgt tttgaatacc attacagcta
    10681 acgaaagctt tagaaaattg gagattagag agattttgta gggtcaatgt accaacaaaa
    10741 gcacctgtaa tatcgcgata atttccacct attaaaatca aatctgttaa ttttcgttcg
    10801 cttaaaatca gaaaaacagg tagactgttg gttacgacgc ggatattgtc aataggcaac
    10861 tcacgcgcaa aaaactctaa tgttgttcct ggtccaatga aaatagtttc tctttcttct
    10921 actagactgc ctgcaaaatg ggctatttct tgtttttctg ccgtttggag ggcttgtttt
    10981 tcaatatttg atcgctcatt agtcaaaagg gagttggttc gaagtttttc agctccacca
    11041 tgcacacgaa tcagcaaatc tttatcagct aattcctgta aatagcgcct tgcagtcata
    11101 tctgaaacgg ctatttcgtc cataatctgt ttaactgtta tggttccttt actatttact
    11161 atctctaaaa ttttggctaa tttttcttgt ttgagcatat tatcacctcg tttcctacta
    11221 ctatcttacc ataaacaaac tcatcattca aatacaaaaa caacaaaatg aaacaaaaac
    11281 aaaaatatcg aagtttgttt tcaaaacttt cgatattttt gttgggttat aactttgatg
    11341 tttctagttt actttttgat gattgagagt gatggagaat tagtctaaac cgtagttata
    11401 gtcatcgtct tgcatgactt caacttcgcc aagaaggtaa ccatttccga cttgagagaa
    11461 gaagtcgtgg ttggaagttc ctgttgaaat accgttcatt acgattgggt tgacatcatc
    11521 agctgaatct gggaagagtg gatcttgtcc catgttcatg agagctttat tggcattgta
    11581 gcgaaggaag gttttaacct cttcagtcca accaacaccg tcataaagac tctctgtgta
    11641 gccttcttca ttttcataaa gagtatagag taggtcgtac atccattctt tgagtttttc
    11701 ttgctcttct tcaggtaatt cattgaaacc aagttggaat ttgtaaccaa tgtaggttcc
    11761 gtgaacagac tcgtcacgaa taatcaattt aatgatttct gcaacgttgg caagtttgtt
    11821 gttaccgaga tagtagaggg gagtgaagaa accagagtag aagaggaagg tttcgaggaa
    11881 gacgctggca actttctttt caagtgggct gccgtttagg tagatttcgt tgacaatctc
    11941 agccttcttt tgtaggtaag gattggtatt ggtccattcg aaaatttctt caatctcagc
    12001 cttagtattc aaggtagaaa agattgatga gtaagattta gcgtggacag attccataaa
    12061 ttggatgtta ttgaaaacag cttcctcatg tggtgtacgg atgtctgcgc gaagggcttg
    12121 aaccccagtt tcagattgca tagtgtcaag aagggttaaa ccaccaaaaa cttttccgac
    12181 caagtctttc tctttgttag atagctttct ccagtcatcc aagtcgtttg ataagggaat
    12241 acgtgtatcg agccaaaatt gctccgtcag tttttcccaa gttgatttgt cgatgacatc
    12301 ttcgatggca ttccagttaa tggctttgta gtaagtttcc atttaaaatc tctttctgtg
    12361 tttagtattg cgaactcaca attatttcta ctttaccata attctatagg agtatcgcac
    12421 aaaaagtcgg aagcccgact tttaaaatgt tacataaatt atgttatgac atagtagatt
    12481 tgattttatc agtgctgctt agggaaaaat agtgttttta tgctagaaac taaatcacac
    12541 agctttcaca ttggttggcg ccgacttctc caccgtcatc tgtaaaggta cggacgtagt
    12601 agatagactt gattcccttg ttaaaggcat agttacgaag gatggacaag tcacgtgtcg
    12661 tttgtttatt ttccctcttc cattcgtaaa ggccttttgg aatgtcactg cgcatgaaga
    12721 gggtgagtga aagtccttga tccacgtgtt cagtcgcagc agcgtaaaca tcgatgactt
    12781 tacgcatatc catatcgtag gcagaagtgt agtaaggaat ggtttctgta gacaagccag
    12841 cagcagggta gtagatttta ccaattttct tctcttggcg ttcttcgata cgttgcgtaa
    12901 tcgggtggat agaagcagaa acgtcgttga tatagctgat agaaccattt ggcgctacag
    12961 caaggcgatt ttggtggtaa agaccatctt cttgaacctt gtcgcgaagt tcagcccaat
    13021 cagcaacacc agggataaaa acatttttga agagttcttt aacacggtct gatgttggaa
    13081 caaattcacc agttacatac ttgtcaaagt aacttccgtt agcatagtct gatttttcaa
    13141 agttgtggaa ggtaatacca cgctcacgcg caatattgtt tgactctacc aaggtccagt
    13201 agttcataag cataaagtag atgcttgtaa attcaacaga ctcaggtgaa ccatattcaa
    13261 tgagttgttg ggcaaggtag ctgtgcagtc ccatggcacc gagaccaaag gtgtgggctt
    13321 ggctatttcc atggtcaatc gttggtacag ctacgatatg tgaactatct gtaacgaaag
    13381 taagggcacg aaccatagca cggatagaac gaccaaaatc aggtgaagtc atcatgttaa
    13441 ccacgttggt tgaacccaga ttacatgaaa catctgttcc catttgaagg aattcttgag
    13501 catcgttgat caagcttggt tcttgaactt gaagaatctc agaacacaag ttactcatga
    13561 taatctttcc atcaacagga tttgcacggt tagctgtatc gatgttgact acataaggat
    13621 agccagactc ttgttgcaat ttagagattt cagtttccaa atcccgcgcc ttgatttttg
    13681 tcttgcgaat atttggattt gcgaccaatt catcgtattt ttcagtaatg tcgatgtaat
    13741 tgaatggcac accgtattct ttttctacag agtaagggct gaagaggtac atttcttcat
    13801 ttttacgagc caattcgtag aatttatcag gtactacaac accaagtgat agagtcttga
    13861 cacgtacttt ttcatcagcg ttttctttct tagttgaaag gaaagcgatg atatctgggt
    13921 gaaagacgtt gaggtagaca acaccggcac cttgacgttg ccccaattgg ttggagtaag
    13981 agaagctgtc ttcaaaaagc ttcataacag gaacgacacc tgaagcagct ccttcatagc
    14041 ctttgatagg tgcaccagct tcacgaaggt tgctgagggt aattcccaca ccaccaccaa
    14101 tacgtgaaag ttgaagagct gagttgatag aacgtccgat agagttcata tcatccgtca
    14161 cttggattag gaaacaagat accaactccc cacgacgagc acgtccagca ttcaagaagg
    14221 aaggagtagc aggttggtag cgttggtgga tgatttcatt ggcaatatcg attgcaacag
    14281 cttcattccc atcagcgaaa taaagggcgt tgaagaagac acggtcttcc atattttcaa
    14341 gatagtattc accgtcatta gtctttaagg catattgatt gtaaaattta taagctgcca
    14401 tgaatgactt gaattggaag ttttggtctt tgataaattg agccaattct tccaagaact
    14461 ctggacggta tttcttgata aaggctgttt cgatgtagtt gtgttcaatg aggtaattga
    14521 ttttgtcttt gattgaatca aaaaccatag tgtttggaac tacattttct ttaaagaaag
    14581 catccaaggc ttccttatct ttatgaagca tgatttgtcc attaacagga cggttaattt
    14641 cgttattaag acggaagtaa gtcacgtctt caagatgttt taatcccata aaatttccct
    14701 tatctaatta caaaagaaag gcttctaagt tagccctaaa agcagtttct tctggatgat
    14761 gtactaagat tatgctaatt gtttcagttt tcctggttgg aaacctgaaa agacttcagt
    14821 tggtgtttgg ataacaggag ctgcgctaaa accgagctct ttaacttgat cgacgtactc
    14881 aggttgctca tcaagattga tttcacgata agagacatta ttactgtcca agaaacgctt
    14941 ggtcatttta cattggacac aattgttttt agaataaacg gttaccattg tgtaactcct
    15001 cttcaaaatt taatactatc ttagtatatc agaaaataaa attttgtcaa tgatttaaac
    15061 taaatatagt ggtgttcttt tgttgttttt
//
LOCUS       DAVKZI010000044        14528 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKZI010000044 DAVKZI010000000
VERSION     DAVKZI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.045"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            13..1014
                     /locus_tag="VXB18_001733"
     CDS             13..1014
                     /locus_tag="VXB18_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0382902.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1616..1696
                     /locus_tag="VXB18_001734"
                     /pseudo
     CDS             1616..1696
                     /locus_tag="VXB18_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2046..2201
                     /locus_tag="VXB18_001735"
     CDS             2046..2201
                     /locus_tag="VXB18_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382903.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            2336..3697
                     /gene="trpE"
                     /locus_tag="VXB18_001736"
     CDS             2336..3697
                     /gene="trpE"
                     /locus_tag="VXB18_001736"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0382904.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYLYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGAMDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKSTLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3694..4260
                     /locus_tag="VXB18_001737"
     CDS             3694..4260
                     /locus_tag="VXB18_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0382905.1"
                     /translation="MILLIDNYDSFTHNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDKAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4271..5275
                     /gene="trpD"
                     /locus_tag="VXB18_001738"
     CDS             4271..5275
                     /gene="trpD"
                     /locus_tag="VXB18_001738"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0382906.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLAFK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5272..6039
                     /gene="trpC"
                     /locus_tag="VXB18_001739"
     CDS             5272..6039
                     /gene="trpC"
                     /locus_tag="VXB18_001739"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0382907.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAEDVAQRIKELQIDKG"
     gene            6026..6625
                     /locus_tag="VXB18_001740"
     CDS             6026..6625
                     /locus_tag="VXB18_001740"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0382908.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            6603..7826
                     /gene="trpB"
                     /locus_tag="VXB18_001741"
     CDS             6603..7826
                     /gene="trpB"
                     /locus_tag="VXB18_001741"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0382909.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7819..8595
                     /locus_tag="VXB18_001742"
     CDS             7819..8595
                     /locus_tag="VXB18_001742"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0382910.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(8567..8668)
                     /locus_tag="VXB18_001743"
                     /pseudo
     CDS             complement(8567..8668)
                     /locus_tag="VXB18_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            8897..9614
                     /locus_tag="VXB18_001744"
                     /pseudo
     CDS             8897..9614
                     /locus_tag="VXB18_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9629..10780
                     /locus_tag="VXB18_001745"
     CDS             9629..10780
                     /locus_tag="VXB18_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0382911.1"
                     /translation="MFNGQVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(10832..11491)
                     /locus_tag="VXB18_001746"
     CDS             complement(10832..11491)
                     /locus_tag="VXB18_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0382912.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWEWLSLGQVVLITAG
                     VTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            11561..12007
                     /locus_tag="VXB18_001747"
     CDS             11561..12007
                     /locus_tag="VXB18_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0382913.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12152..12424
                     /locus_tag="VXB18_001748"
                     /pseudo
     CDS             12152..12424
                     /locus_tag="VXB18_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12534..12737)
                     /locus_tag="VXB18_001749"
     CDS             complement(12534..12737)
                     /locus_tag="VXB18_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0382914.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(12768..13376)
                     /locus_tag="VXB18_001750"
     CDS             complement(12768..13376)
                     /locus_tag="VXB18_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0382915.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(13415..13585)
                     /locus_tag="VXB18_001751"
     CDS             complement(13415..13585)
                     /locus_tag="VXB18_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0382916.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(13597..14163)
                     /gene="amaP"
                     /locus_tag="VXB18_001752"
     CDS             complement(13597..14163)
                     /gene="amaP"
                     /locus_tag="VXB18_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0382917.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(14247..14411)
                     /locus_tag="VXB18_001753"
     CDS             complement(14247..14411)
                     /locus_tag="VXB18_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0382918.1"
                     /translation="MGIIANVFAGLVGASAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
BASE COUNT         4563 a         2603 c         3152 g         4210 t
ORIGIN      
        1 tggaggactg aaatgaaaaa tataaatggg aaaaaggtaa ctatttatga tattgcacgt
       61 ttatcaggtt tttctccaaa aacagtttca cgagttatta atggtggagt aaatgttaaa
      121 gaagaaactt atcaagcgat tcaaaaagtt atagaggaat tgtcgtatat tccaaatgcg
      181 tatgcaaaaa atttaactaa aaaagaagct ataaatatat tgatttctgt aaaaaaaatc
      241 gactcttttc ctttaatttg gtttcatacg ctgttagata aagtgttacg gacgtgtaaa
      301 gaatttggtg ttaatgctat agttgagtac tttggagagg aggatacaat tagtaattca
      361 attatatcaa gcacaggtag cctagtagat ggtgttattg ttttttatga aagtgtagat
      421 gatatcagaa ttcagtattt aaagaagaac catatgcctt ttcttgtttt cggtgaatct
      481 caaacgtctg gagtagtcta tgtatctaat aataattttc aagctactta tgatatgatg
      541 aaagctgtaa ctgaagaaaa atttaaaaat atgtggttgc ttatgggagg agaatcccat
      601 gttaataagg atcgtgaaag aggtgtgcgt tcttttctga atgataaaaa ttactttatg
      661 gatttaaaag tcatttatgg cttatctaca attgattcag tttattctta tgcaatgcag
      721 cacttgacta cccaaaatta tccggacatt atttttgttt caggagatga aaaggttcag
      781 ggcttgattc gtgcttgcta tgagaaagga attcttattc cagatgatat ttctatcatt
      841 ggatttgata atattcctat ttctcagtat tatactccag ctttgtctac aattgctccc
      901 aattatgtta aattggctaa agaaatgata gaaggtgttt tagcaattat taaaggggaa
      961 agtgtcacat ctgttgaagt ttctcctaaa tttgttagga gacagagttt ctagtattgt
     1021 ttaattcttg aaaatcctag tggaaaagat ggagtgttct aaaataagtt ctgtttagcc
     1081 tccattcagt ttctattgag ttggatccaa tttctaacga gtgggacatg ttcatgttcg
     1141 atctaaggaa gacatggtca cattcgaatg atattttcaa aaaaatcgta aaaaagtctt
     1201 gacaaagaaa aaacaaagta ttaaaataag ttcaacaaat cagaaaagta actatttttg
     1261 atcttcaggg agcctgtggt gattgtgaat aggtggttgg aagtagtgaa agtgggctga
     1321 ttttgaaaat gaatttgaaa caatgaaaat tcggtgcgca caccttacag tgcagcttgt
     1381 tgttaaacaa ggcagagatg taaagggata atccctttat aattgaggtg gcatcgcgtt
     1441 atcaacgccc tcacacggaa gtatattctg tgtgtgggct tttttctatc cgtcgtttgg
     1501 tttatctttt attagggcct taagtcgctt tgatgaactt gagttctatc tacagctcct
     1561 tgcctactac taaaagcaaa caaaaaggct ggactaatac gaaaaaagct agtaatactc
     1621 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaaac actgttttga
     1681 ggttgtggat agaactgacg aagtcagctc aaaatactgt tttgaggttg tggatagaac
     1741 tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg aagtcagctc
     1801 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga
     1861 ggttgcagat agaactgacg aagtcagtaa ccatacctac ggcaaggcga cgttgacgcg
     1921 gtttgaagag attttcgaag agtataaagg tgtaccgaga tgaacatctc ttcatcaatg
     1981 tctctggtcg tggaggcaag gacctagctg cgattgcaga ctacctagaa gctaaaaaat
     2041 aatagatgga aaaattacag ttctttctct cacagagagc ttgtggttgc tggaaacaag
     2101 cagagaaagc tgtaaagttg ggttcatctg aaacgagaga agaaaacatc attctcaagg
     2161 gagtgccctt tatcgcacag cctgttacag gagatatctg agacaggaat gagagatagg
     2221 agaaatccta taattgaggt ggcaccgcga atttcgtcct cacgcaagtt attttgcgtg
     2281 gggatttttc atatagtcac cacggactag aagtagaact gaaagggaaa ttacaatgga
     2341 acgaatcatt catggagatg tcttatcacc aatcttggct tatatgcgct taaaggggca
     2401 acacaaggtt atcttagaga gtattccgag agacaaggaa acagctcgtt tttctatctt
     2461 agcctataat cctgtttttg agattaagtt tgaaaatgga gttctttatc aaaatggtca
     2521 agtgattgat cgggatccct tggatttcct ttatgaagtg attcataaga gtcagcacca
     2581 ctcagagcta ccttttggtg gtggagccat tggttttgtg ggttacgata tgatttcgct
     2641 ttatgaagaa attggtcaaa tccctgagga tacaattggg acgccagaca tgcatttctt
     2701 tgtctatgag agctatatgg tctttgacca caagaaggag aagatacatg tcatagagga
     2761 tgcactttat agtgagcgca gtcaagaagc cttggaaaaa tccttgaacc aagtgcttga
     2821 ggaattacgc attcctgctc caaatgaatt tgaagacttg gatctatctc cgttagactt
     2881 caaaccccat atcgctcctc agaagtttga ggaaatggtg gaaaccgctc gcgacttgat
     2941 tcgtaatggc gatatgttcc aatgtgtact cagtcagcgc ttctcagcag aagttactgg
     3001 aaatccattt gacttctaca gaaatctccg cgtgaccaat ccatccaatt acctctattt
     3061 atatgacttt ggggattatc aaatcatcgg tgccagtcca gaaagtttgg tttctgtcaa
     3121 aaatggcatc gtgacaacca atccgattgc agggacgcga ccaagagggg ctatggatga
     3181 agaagacaag gccttggcga ctgacctcct ctctgatgag aaggaaacag cagaacatcg
     3241 aatgttggta gacttggggc gtaacgatat tggccgcatc tctgaaacgg ccagtgtcca
     3301 agtcactaag tatatggaag tggagctctt ccgttatgtt atgcatctga ccagcgtggt
     3361 caaggggcgt ttgcttccag aactcactgc tatggatgcc ttgaaatcaa cgcttccagc
     3421 tggaaccgtt tctggagcac caaaaattcg agctatgaga cgcatctatg aactggaaac
     3481 ggaaaaacgg ggcgtatatg caggagcaat cggctacttg tctgcgacgg gtgatatgga
     3541 tttggccatt gccatccgaa ccatgattct caaaaatcaa agagcctatg tgcaggctgg
     3601 ggcagggatt gtctacgact ctatcgccca aaacgaatac caagaaacca ttaacaaagc
     3661 aaaatctatg actagaattg gagaactaag accatgattt tattgattga caactatgat
     3721 tcttttaccc ataacttggc ccaatacatt gggaattttg cagaagttca ggttctgaga
     3781 aatgatgatt ccaagctgta tgaagaagct gaaaaagcag atggtctggt cttttctcct
     3841 ggtcctggtt ggccagttga tgctggaaag atggaagaca tgattcgtga ttttgcaggc
     3901 aagaagccga ttcttgggat ttgtttgggc caccaagcca ttgcagaagt ctttggtggt
     3961 aagctaggtt tggctccaaa agtcatgcat gggaaacaga gcaatatcaa ctttgaagcg
     4021 ccatctgttt tgtatcaagg tattgaggat ggccgtgcgg tcatgcgtta tcacagtatt
     4081 ttgattgagg aaatgccaga agactttgaa gtgacagctc gttcgactga tgacaaagcc
     4141 atcatgggga ttcaacataa aaacctaccg atttatggct tccagtacca tccagagagc
     4201 attggaacgc cagacggctt gtcttctatt cggaatttta tcgagaaggt tgtaaagtga
     4261 ggaaactagg atgaaagaga ttattgaaaa actagcaaaa tttgaaaatt tatcaggtgt
     4321 ggaaatgacg gatgtcattg agcgtatcgt aactgggcgt gtaactgaag cgcagattgc
     4381 ttctctcctc ttagctttta agatgaaggg ggaaacacct gaagaacgca cagccattgc
     4441 ccaagtcatg agaggacatg cccagcatat tccaactgag attcatgatg ctatggacaa
     4501 ctgtggtaca ggtggggaca agtctttcag ttttaatatt tccacaactg cagcctttgt
     4561 cttggctggt ggcggtattc acatggccaa gcatggtaac cgctcgattt cttctaaatc
     4621 tggttccgca gatgtcctcg aagccttggg aatcaatctt gacctcaaac cagctgaact
     4681 aggtaaggtc tttgataaaa ctggaatcgt ctttctcttc gctaaaaata tgcacccagc
     4741 tatgaaatac atcatgccag ctcgtttgga attgggaatt ccaacgatta tgaatttgac
     4801 tggtccactg attcatccaa tggctttaga aacacagctt cttggaatta gtcgtccaga
     4861 actcctagaa agtacagctc aggttttgaa aaatatgggt cgcaaacgtg ccatcgtggt
     4921 tgctggacca gaagggttgg atgaagctgg cttgaacgga acaaccaaga ttgcacttct
     4981 tgaaaatggc gaaatcagct tgtcaagctt tactccagag gatttgggaa tggaaggcta
     5041 tgctatggaa gatattcgtg gtgggaatgc tcaggaaaat gcagaaattt tgcttagcgt
     5101 tctgaaaaac gaagcaagtc cattcttgga aacgacagtc ttgaatgctg gtcttggttt
     5161 ctatgctaat ggtaagattg atagcatcaa ggaaggagtt gccttggccc gtcaagtgat
     5221 tgctagaggc aaggcccttg aaaaactcag actgttacag gagtaccaaa aatgagtcag
     5281 gaatttttag cacgaatctt agagcagaag gcgcgtgagg tggagcagat gaagctggag
     5341 caaatccagc ctctgcgcca gacctatcgc ttggcagaat ttttgaagaa tcatcaggac
     5401 cgcttgcagg taatcgctga ggtcaagaaa gctagcccta gtttgggaga tatcaatctc
     5461 gatgtggata ttgtgcaaca ggcccagact tatgaagaaa acggagcagt gatgatttcg
     5521 gtgttgacag atgaggtttt ctttaaaggg catttggatt atctacggga aatttccagt
     5581 caggtagaga ttccgacgct caacaaagac tttatcatcg atgaaaagca aatcatccgc
     5641 gctcgcaatg caggtgcgac agttatcttg ctcattgtgg cagccttggc agaagaacgt
     5701 cttaaggaac tttacgacta cgcgacagtg cttggtctgg aagtcttggt ggaaactcac
     5761 aatctagctg aactagaagt ggctcacaga cttggtgccc agattatcgg ggtcaataac
     5821 cgcaacttga ccacctttga ggtcgacttg cagaccagtg tagacttggc taaacatttc
     5881 aaagatgatt gcttgtacat ttctgaatct gctattttca cagggcagga tgcggaacga
     5941 ctagccccat actttaacgg aattttagta gggacagctc tcatgcaggc agaggatgtg
     6001 gcccagagaa tcaaggagtt gcagattgac aaaggttaag atttgtggac tatcgaccaa
     6061 agaagcggtg gaaacagccg tttcagcagg agccgactac atcggttttg tcttcgcacc
     6121 tagtaaaaga caggtaactt tagaagaggt agctgagttg gcaaagctta ttcctgcaga
     6181 tgtgaaaaag gttggagtat ttgtttcacc aagtcgggta gaactgctgg aagcgattga
     6241 caaagttggc ttggacttgg ttcaagttca cggtcaggtg gcagatgatt tatttgagaa
     6301 tttgccttgt gccagtattc aggctgtgca ggtagatgga aatgggcatg tccccaattc
     6361 tcaggcagat tatctactct ttgatgcccc tgtggcagga agtggccagc cctttgattg
     6421 gggtcaactg gatacgactg gactagcaca gcccttcttt atcgcaggtg gccttaatga
     6481 agataatgta gtaaaagcaa ttcaacattt tactccctat gcagtagatg tatcgagcgg
     6541 agtggagaca gatggacaaa aagatcatga aaagattaga agatttatag agagggtaaa
     6601 gcatggcata tcaggaacca aataaagatg gattttacgg aaaattcggc ggacgttttg
     6661 tcccagaaac attgatgaca gcagttttgg agttggagaa ggcctaccgt gaaagtcagg
     6721 cagacccaag tttccaagag gaattaaacc agcttttgcg ccagtacgta ggacgtgaaa
     6781 ctcctcttta ttacgcaaaa aacttgaccc agcatatcgg cggagccaag atttatctca
     6841 aacgggaaga ccttaaccat acaggagccc acaagattaa caatgcctta ggacaagttt
     6901 ggcttgccaa acgcatgggt aaaaagaaaa ttatcgcaga aacgggtgct ggtcagcacg
     6961 gtgtggcaac tgcaactgct gcggccctct ttaacatgga atgtaccatc tacatgggtg
     7021 aggaagatgt caaacgccaa gccctcaatg tcttccgcat ggagcttttg ggagccaagg
     7081 tcgaggctgt aacagatggt tcgcgcgtgc tcaaggatgc ggtcaatgca gcccttcgtt
     7141 catgggtggc taatatcgac gatacccact atatccttgg ttctgccttg gggcctcatc
     7201 catttccaga aatcgttcgt gacttccaaa gtgtcatcgg tcgagaggct aaacaacagt
     7261 accgtgactt gacaggtcga gatctgccag atgccctagt agcctgtgtt ggtggtgggt
     7321 cgaatgctat cgggctcttc catccctttg tagaagatga gtcagtagct atgtatggaa
     7381 ctgaagcagc agggcttggt gtggatacag agcaccacgc tgctaccttg accaagggtc
     7441 gtccgggtgt tcttcacggt tctctcatgg atgtgctcca agatgcccat ggtcaaattc
     7501 ttgaagcctt ctctatctca gcaggtttgg actatcctgg tatcggtcca gagcattctc
     7561 actaccacga tattaaacgt gccagctatg tccctgtgac agacgaagaa gccttggaag
     7621 gatttcaact cttgtctcgt gtggaaggga ttatcccagc tttggaatct agccatgcta
     7681 tcgcttttgc ggtgaaattg gccaaagaac ttggaccaga aaagtctatg attgtctgcc
     7741 tatcaggtcg tggggacaag gatgtggttc aagtcaaaga ccgcttggaa gcagatgcag
     7801 caaagaaggg agaagctcat gcctaagaca ctaacagaaa aattgaatgc tataaaagta
     7861 actggaaaag gaattttcgt tccttatatc atggctggtg accacgaaaa aggtttggac
     7921 ggtcttgctg aaacaattca ctttttagaa gatttgggtg tctctgctat tgaagtgggg
     7981 attccctttt cagaccctgt tgcagatgga cctgttatcg aagaagctgg cttgcgcagt
     8041 ttagcccacg ggacctctac ccaggcttta gttgaaacct tgaaaaccat tgaaacagag
     8101 attccactgg tcatcatgac ctacttcaac cccctctttc agtacggtgt ggagaacttt
     8161 gtcaaagatc tggctgatac agctgtgaag ggcttgatta tcccagacct gcctcatgaa
     8221 catgccaact ttgtagaacc atttttggca gatacagata tcgccttgat tcctttagta
     8281 agcttgacca caggaattga gcgccagaaa gagttgattg aaggggcgga gggattcgtc
     8341 tatgccgttg ccatcaatgg ggtgacaggg aaatcaggca attaccgtgc agatttggac
     8401 aagcacttgg cgcaacttca tcaagtggcc gacatcccag tcttgacagg ttttggtgta
     8461 tctagtcaag ccgatctgga acgcttcaat gcggtgtcag atggtgttat cgtcggttca
     8521 aaaatagtaa aagctctcca ccaaggagag ccgattcagg attttatcag acaagcagta
     8581 gcttaccaaa aataatcaaa caagtagcaa gtaagaggaa aggcacgaaa ggaagtcttt
     8641 cctttttctt ttgcaggaga aaggctagtt ttatagtgaa ttgaatctgg aatattacac
     8701 tacggttcct aaaatatttt cagaaagcga tttgaatttc ccaataaatt tgttcagttt
     8761 ttaattgatt ttactataga agatataatt ttctaaatta ctctgacaca gaactttaag
     8821 aaaaagctaa ttattgtagt aatttattta agaaaatgat ataattcatt aaaaagtatt
     8881 tggaggagga agaattatgt tgaatcagga tctctttgat tcgcttgagg cacaaaaaat
     8941 tgtagatact ttgatgaaag ggcaaaaaga ttatgtagat gaacgtctag aaaaaagaga
     9001 gacaatgata gtgtcgaatg gttatgcatg gacgcgacct aatcatattg atactgcatt
     9061 tgcatcagca gatttgtttg agtataaatt acaattagca ggacagactt ggggatattt
     9121 agaatttgaa acaaatacag aaaaatatgg gaaagtattg ttaattataa agggtaagaa
     9181 gcgacttacg aaccaatttc ctttggtaca aaaaaataag agtggctact tatttgaata
     9241 cactttatct taatcaacat tcttcctaca aaaatgatga agatagtcat tcctttccaa
     9301 ttcagatgga gttagtttct gatgaaatga ttcaagaaat tgaacaagct actaaaaatt
     9361 cgaatatcga aaaatttatg attttaactt atgaggcgga ctcagaaaac aatattatat
     9421 ctgtagatgt tgttatgcct gatgcacgaa ctggtcagtt acacttgatt caagatttgt
     9481 ctgagtatat tcaatcaagt tcgtaccatt tcgaagaagc taaatatcaa gatattccta
     9541 atttttcaga attatcggaa acagaagatt ttgaaattat tccaagaata gaaaaacaag
     9601 aaggtcaaaa gtagtaagga gtatgtaaat gtttaatggt caggtattga aagaattacg
     9661 gctgttaaat ggtttaagta gagcagaatt agctcagaga attaatttaa cggaacaagc
     9721 catttggcag tttgagtcca acgaaacgaa acctaaatta tcaaccaaaa tgcatttggc
     9781 caaccaattt catgttgatt taacttattt tgaacaggaa gaagagagca ttcgatttga
     9841 ttcttctgta attgccttta gaaatgcaga cctagcaaca cggaaaacaa tagatattca
     9901 aactatgtat ttacataagg tagatagtct gattgattat tttgaaagtt ttgtaattat
     9961 acctaatatt acaattcatg acttaagtaa tgtagtgagt gaatcttatc ataagggaga
    10021 atccattgag gaattggctc tttatgccag ggaaaaatta ggtatttcaa aagataatca
    10081 tgatttgctt tataaattag aacgttcagg catctatatc gtggaacgat taattaatgg
    10141 ccaagctgat gcttatagcg catggtcaaa attgggaaga ccttatattg tgttgggaac
    10201 gaataaatca tctgtacgtc gaaattttga cttagctcat gagctaggac atattctttt
    10261 acataaatat aaagatatga atgaagatgg cgatcgtttg gagcaagaag caaattattt
    10321 tgcatcatgt tttttattgc caaaagaaga gtttttagtc aaatttgaag agagggttgg
    10381 caagcgtgtc agcaatcctg atagttatat tttattgaag tcagatttga atgtttcgat
    10441 acaggcttta gagtatcgag cttttaagtt aggattattg actccaaagc aacattctta
    10501 cttttatcgt caaattgcgc aaaaaggtta caaaatgatt gaacctttgg atgatcaaat
    10561 ttttgttaaa aaaccaagca aagtaaagag tattctggac gtcgttttga gtaatcatct
    10621 agtcagtcta gcgactataa tgtctaaaca aagtattcgt ttacagttta taagcgaaat
    10681 attttcagtc gaaatgaaat tttttgatca gtatcaagaa gatagaagaa cagatcgatt
    10741 tgataacatc atccctttgt acaaaagaaa taatttataa tttaactgtg aaataatttc
    10801 atgaaggaca tatggcagaa attggatttt atcagacaag cagtagctta ccaaaaataa
    10861 tcaaacaagt agcaagtaag aggaaaggca cgaaaggaag tctttccttt ttcttttgca
    10921 ggagaaaggc taggataccc gtcgcagaag caaactgaat caagatcagt aactccgtta
    10981 tgctaaagac gagagcacaa gaagctaaaa agaggaaatc ccctgcgccc atgcggatat
    11041 cgataaaatg agccaaaatt ccaagagcaa ggaaggagac catgaccaga ttccagccag
    11101 aggaagctat taggattagg tggaaagtca tccagaccag taagggatat tcctgatggc
    11161 gaaagtcata gatgctcaag gtcacaccag cggtgattag gacgacttgc cccaaggaga
    11221 gccattccca agagtaaagc agaaagagga gtcctaagcc tagttcaaag agggcatacc
    11281 agacaggata gcggaccttg cagtagcgac agcaaaagcg attgaagacc tgtgagagaa
    11341 tcggaatcaa atctaaggga cgcaagcgag tctgacagga atcgcagtga ctggctgaac
    11401 tgataatgga ttgctctgga aaacggtcaa tgaccaaacc aagaaaggaa gcgagaatgc
    11461 tcccgacgag aaaaaaataa aaatcaatca tacttatcta ttcgtaaaaa atgggagaaa
    11521 tagtataatg gagaaacata gataagatgg tgaggaaaag atgacaattc gttttgaaga
    11581 aaaggtgagc acagaaaacg ctcaatttgt atgccagtgg tccaactccc taggcaaatc
    11641 ctttcaagaa caatggatgg gaccaaggat tccttttcta ctgacccttc aagccttgga
    11701 aggagtcttt tcaatctttg atgaacaaga gtttgtggga ctaatccaga aaatcaggct
    11761 agaagacagc aatcttcata tcgggagatt ttttatcaac ccccagaaac aggagcaagg
    11821 cttaggtagc caggctttaa ggaaatttgt tagtttggcc tttgaaaatg aagatataga
    11881 tagtatttct ctaaatgtct tcgaggcaaa tcaaagagct cagaatcttt accaaaaaga
    11941 aggatttgaa atcgttcaaa tggttgaagc acctgtacga aaatatagta gattgaaact
    12001 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg tcccgatcga
    12061 ttcgtcctgt tattatttca ttttactata cattatgaaa aaggggagat agaaagcaaa
    12121 cagccttgaa atcaatgttg actgcgatta tgaacctgaa tcagcccctc aaaagggact
    12181 gtatatgaat gaacgttacc agtgtttaaa aactaaagaa tatcaggcac ttttatcttc
    12241 caagggtaga caaattttcg ctaaacgtaa gattgatatg aaatctgtct ttgggcagat
    12301 aaaggtttgt ttgggttata agagatgtca tctgagaggt aagcgtcaag tgagaattga
    12361 catgggattc atactcatgg ccaacaacct gctgaaatat aataagagaa agaggcaaaa
    12421 ttaaaaagct agagttccgc aattgggaat ctctagcttt ttgttttctg agaatcatct
    12481 tgactcagac tcttttgact aatgttacca aaaagataaa gtaactttta accttattta
    12541 tcgtcgccac tcaacatgtt tttaacacct tctacagcac cttctacagc gtctttagcg
    12601 tcttcggcaa cttcttttac tttagaaaca actttttcag ctgctccttc tttttccatt
    12661 ttttcatcac cgatggcttt cccaacacct tctttaatag aacctttagc ttgatttaat
    12721 ttttcttcta ctgacatgat aatttctcct gttatattta ttttatctta gtttacacga
    12781 gtgttttcgt gagatactac accatttgct gcacctttaa cagcttctac accttcgcta
    12841 actttttctt gaacagttga gaaaccagat ccaagaccag atttagcttt ttcgaattgt
    12901 tctgaagtga attctcctgt tgattcagca acgtcagata cgcgatcttg aaggcttact
    12961 gagtctgctt catgctgttc tttagttttg atgtcgacaa cgtttacgtt gatttcaaca
    13021 atttccaagt cagtcatttt agcaacttct gaagatacga tttctctgat ttctgaatat
    13081 aaagctggaa catttttttg gtactcaaca ataacgttta agtcaactgc aacttgtgtt
    13141 ttaccaactt ctacgttaac accacttgtt acgtcatcgc tgttaacgat tttttcttta
    13201 agatttgaga agaaaccacc atcgattccc aaaagacctg aaacgttttc tagtgaaaga
    13261 ccaatgattt tttggataac tttatcttcg taagtaagtt cccctttgat ttcgtgagct
    13321 acaacagtag catctttctt ttctacgtta gtgtttgtgt ttttttcgtt tgacatatga
    13381 aactccttta attaaattag taatttttat ttttttattt atctatatag tttttttcga
    13441 tatataatcc agctgcaact cccagtgctc ctaaaatcaa tacaaatatt gttttgaaga
    13501 agccaaagga gacaatcaaa caagccagaa atacgcctat gagaccagcg ataattggat
    13561 atcgatattg tttaagccat tccatttttt acttccttac ttcacacgac taacagtctt
    13621 tttgttttga ggttttggtt ggtaattttt tactgcaact tcaagtttta cttgacgctc
    13681 aataccaaaa aactgcttca atccattagt tatttcattt tgaattattt ggcatctgtc
    13741 agcgatgttg tctgaaggaa gaattttacc ttctacatga acgaaacatt tattttttcg
    13801 taaatttaca tgaacagttg ggttcttgat caatctatga tcactcacca aacttctaac
    13861 aaaaccttcg attgccgaat tctttaattt taatgtatcg tttttagttt caagttggat
    13921 ttccaagtaa cgtttaggat aaaacatcac aactaaaatg gataataaaa ctaaagttga
    13981 tagaaccact gtcccccaaa agacatatct agcaagatag aattcaacta cggagttctg
    14041 tctccagcta agtagatgaa tacctagatc actaacttga tgataatcta tcaaaacagg
    14101 aaggaaaatt gtcaagatta aaatacagaa aataatgaaa catattttct ttgcttttga
    14161 catatacaat cctttcgatt taacatttaa actatttttc ccgtcattga tttaaaaata
    14221 gtttgctaac tttactggcg aaaagtttac tttctacctg taaagaatga cactacagta
    14281 atcacaatcg ctgcacctac aatagatggg agcaaagcca ttccagcgat tgatggaccc
    14341 caactaccta aaagagattg tcctgcagat gccccgacta aaccagcgaa tacatttgcg
    14401 atgattccca tagaactact tttttagtga ttttacctgc caagagacca ataagacctc
    14461 cagcaataat tgatcacaac actgcctacc ctccttttta ttttaatatc aaaaaatcaa
    14521 tttctttg
//
LOCUS       DAVKZI010000045        14466 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKZI010000045 DAVKZI010000000
VERSION     DAVKZI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.046"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(662..1642)
                     /locus_tag="VXB18_001754"
     CDS             complement(662..1642)
                     /locus_tag="VXB18_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0382919.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1980..2129)
                     /locus_tag="VXB18_001755"
     CDS             complement(1980..2129)
                     /locus_tag="VXB18_001755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382920.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHRFEVADRTDEVS
                     NIYIR"
     gene            complement(2157..4172)
                     /gene="recG"
                     /locus_tag="VXB18_001756"
     CDS             complement(2157..4172)
                     /gene="recG"
                     /locus_tag="VXB18_001756"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0382921.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(4191..5294)
                     /locus_tag="VXB18_001757"
     CDS             complement(4191..5294)
                     /locus_tag="VXB18_001757"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0382922.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(5284..5652)
                     /locus_tag="VXB18_001758"
     CDS             complement(5284..5652)
                     /locus_tag="VXB18_001758"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0382923.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5691..6722)
                     /locus_tag="VXB18_001759"
     CDS             complement(5691..6722)
                     /locus_tag="VXB18_001759"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0382924.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6724..7755)
                     /locus_tag="VXB18_001760"
     CDS             complement(6724..7755)
                     /locus_tag="VXB18_001760"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0382925.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7836..10349)
                     /gene="secA"
                     /locus_tag="VXB18_001761"
     CDS             complement(7836..10349)
                     /gene="secA"
                     /locus_tag="VXB18_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0382926.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10495..10782)
                     /locus_tag="VXB18_001762"
     CDS             complement(10495..10782)
                     /locus_tag="VXB18_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382927.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFELICCLSLWINLFITFAILPIFGN"
     gene            complement(10810..11442)
                     /locus_tag="VXB18_001763"
     CDS             complement(10810..11442)
                     /locus_tag="VXB18_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0382928.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(11446..12087)
                     /locus_tag="VXB18_001764"
     CDS             complement(11446..12087)
                     /locus_tag="VXB18_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382929.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(12080..12871)
                     /locus_tag="VXB18_001765"
     CDS             complement(12080..12871)
                     /locus_tag="VXB18_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382930.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12893..13285)
                     /locus_tag="VXB18_001766"
     CDS             complement(12893..13285)
                     /locus_tag="VXB18_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382931.1"
                     /translation="MKTKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13593..14444
                     /locus_tag="VXB18_001767"
     CDS             13593..14444
                     /locus_tag="VXB18_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0382932.1"
                     /translation="MRWDYEQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLSEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKVFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
BASE COUNT         4353 a         3207 c         2636 g         4270 t
ORIGIN      
        1 ctcattttta aaacgctttc aatatagtgt aatatagtag attttagttt caaaaaattc
       61 ttttatataa taatgtcctt gaaagtagtt tcagctgaac atttataatc cataaaaaga
      121 aaacagaaac tcatctgttt ttatactcaa tgaaaatcaa agagcaaact aagaagctag
      181 ccgcatgatg ctcaaaacac tgttttgagg ttgtagataa gactgacaaa gtcagctcaa
      241 aacaccgttt tgaggtggca gatagaactg acgaagtcag taacatatat acggcaaggc
      301 gaagctgacg tggtttgaag agacttttga aaagtattaa cacttacaga caagcctgac
      361 gatagcaaga actaccctac tcgataggta tcggcttttg ctttctgaaa aaaattattt
      421 taagcaattt gacaaatcta gcaacaaaaa attctataaa tataatagat tgaaactaga
      481 atagtacacc tttgtttcta aaacattgtt agaaatcgat ttgactgtcc tgatcaattt
      541 gtcctgttct tgtttcattt tactatattt ctatgataaa acgcatagta tcaagttttc
      601 ttaatcccct gatactatgc gtgtttgtaa tttttaagat tttgtactta gagtcgactc
      661 cttattttag atatttaaaa ggaatctcac ttccacagag ccagttgtag acttggtcat
      721 tgacaaatac attcatggct tcgtgagcat actcaggcat gatacgatag gttttatcgc
      781 aggtcagacg attataaatc gcaaactggg taatgggata gcaaacatcg tcgtccaagc
      841 ccgtaatcat cttaacctca ccttggatac gatgggcaag atttttgaca tcgatatagg
      901 caagggtcgc catgatttcc tcctctgttt catggaaggg gtcgtgaaac ttgaaataac
      961 ggaaaagttc gtcgtaagcc tcgctagtat taccaatctc aatcacccgt ctgaagtctg
     1021 acaagaaggg ataaatggca actgttttct gaattcgagg attgagggct gctgcaacta
     1081 gggctagagc ccctccttgt gaggcaccat agctagaaag acgcttctca tcaacctgag
     1141 acagactagc aacaatttcg accaactggt aaatatccag ataaacatcc ttataaaaga
     1201 ggtggtcccg accttccaca gcaccacgga taatatgccc cttcacggta tttcctaaag
     1261 gagaacgcaa gccgtcttgt gagtaacctg actggccccg cacatccatg gaaacaacac
     1321 cgtaaccagc tacggtgaag cccagcatgt cggcccagtc ccagccacgt cccatataac
     1381 catgaaaatg gaagattagt ggaaccttct cctcactctt tggaagaaca atgcgtgcat
     1441 agacctttcc ttccttgctt ccttcaaatg ttaactcata gcacttgact tgaggaatgt
     1501 ggaaatctct ttcctccaag tggtaggatg gaagcgtgga aacatttttc acttccccat
     1561 cccagaaagc atcaaagtct tccggaacct catcccttcc tctataggtc ttaatttctt
     1621 ctagcaaagc tggatttttc atagcatgct ccttttattt tgtaatcgtt accacaactg
     1681 tagcatatct atgtaatcaa tgcaagaaag aagggtaaat agaaagtgaa tttagattct
     1741 ttacttttag gatgatgggc tgaaagtagt tttagaaacg aaaaaagagc atttcgctct
     1801 ctcttctgtt tatactagtt ttttgcttcc ttcttttgga aagtggtttg gtaatttact
     1861 ttaatcgtta ctgtcatatg agagtcctcg tttctttttg atgactttag tataagagcc
     1921 aaacctaaaa actagcttaa tactcttcga aaatctcttc aaaccacgtc agcgtctcct
     1981 taccgtatat atatgttact gacttcgtca gttctatctg ccacctcaaa acggtgtttt
     2041 gagctgactt cgtcagtttc atccacaacc tcaaaacagt gttttgagca acctgcggtt
     2101 agcttcctag tttgctcttt gattttcatt gagtataagt tttccttaga gaaagcttaa
     2161 tccagatgtt ctttcttttc cagatgaagg gcaatcatgc gccactctgg atcttcttgc
     2221 caagcttcta tagaactaat gtagctagca acctttcttg cttcttctaa aatcggaaaa
     2281 tcttcgataa tatcagccac ttggaactct ggaagtcctg actgtctggt tccaaaaatc
     2341 tcaccagaac cacgcatttt caaatcttcc tccgcaagga caaatccatt ggtcgtttct
     2401 gtcatgatgc gcatgcggtc tttcccagaa tccgtcttgg gattggcaac gagaacagcg
     2461 taggactgct tgtccccccg accgacacga cctctaagct ggtgaagctg gctgagaccg
     2521 aagcgatcgg catccatgat aatcatgaca gtcgcattgg gaacgttgac cccaacctca
     2581 ataaccgtcg tcgaaaccag aatatccgtc tttctctcct tgaaatcctg catgatctgg
     2641 tctttttcgt cactcttcat cctaccatgt agaagagcca cctctgcctt gcctgcaaaa
     2701 tgagtcgtca actcctctga taaggcaatg gcatttttca aatctagagc ttctgattct
     2761 tcaatcaaag gagagatgac ataggcttgg gaaccttttt gaatttcccc ctctaaccaa
     2821 gtcaagacct gaggtagttg ctcatgtttg atccagcgcg tcacaatagg cttccgacct
     2881 gctggcatct ggtcgataat ggaaacatcc atatctccaa aggctgtgat ggcaagcgtc
     2941 cgtggaatgg gagtcgccgt catcatgagg acatctggat tgtcaccttt ttcccgtaaa
     3001 atacgccttt gccctacacc aaaacggtgc tgctcatcga taataatcaa accaagacga
     3061 gcatactcca ccccatcttg tatcagagcg tgagttccga taatcaaatc agcctcaccc
     3121 ttggcaatgg tctccaagac ttctctcttt tctgcagctt tcaaggaacc tgtcaagaga
     3181 gccagtttca aattgggaaa aaggttctgt aaactctcaa agtgttgctc tgcgaggatt
     3241 tctgttggta ccattagggc agcctgataa cctgctgtca ctgccgcaaa catggccaag
     3301 ccagcgacta ccgtttttcc actccccaca tccccttgta ggagacgatt catgtggtgg
     3361 tcggacttca tatcagttaa aatttcctgc aaactctttt cctgagcttg ggtcagggca
     3421 aaaggaagac ttactttaac tgctgtcact ttttcctgag accaattcag aaccagacca
     3481 cttccctgaa ctctattttc agacttgagc gtctgcaact gcatttggaa ataaaagagt
     3541 tcctcaaact tgatacggcg aagagcctgc ttgtattctg ccaaatcctt tggaaaatgc
     3601 atagctcgga ctgcctgaca acgggacatg agtttgtatt tgtctagtaa agactggggc
     3661 agattttctt ctatcaagag gtccagtccc tgatcaaaag ccgtcttgat gaccttaacc
     3721 agactggcct gactgattcc ctgagccaga cgatagacag gctggaggtc atcttctacc
     3781 tgagccagaa ccttcatccc agtcagacta gccttagcgc ggtcccattt tccaaagaca
     3841 gcaagggttg ctcccaactc tattttatca gccagatagg gctggttaaa gaaattcacc
     3901 gcaaaaacga cctctccctg cttgagacta aaacgcaggc gattgcgctt gaaaccataa
     3961 tactggacac tagcaggagt cactacctga ccagaaagaa ctgccttctc accgtcttcc
     4021 agctccagca cctgcttggt tttgaagtct tcataacgga aaggaaagta gagcaagaga
     4081 tcttgcaagt tttcaattcc tagtttggcg tatttttctg ctgactttgg tcccacacca
     4141 ggcaagacat gcaagggttg atgtagattc atgctccact cctttctttt ctaataatat
     4201 tctctcggaa tacggtcgct gaggaggcaa accacctcat agttaatggt tacgcggtag
     4261 gtcgctacct gagttgcagt gatttcctta tccccattgg agccaatcaa ggttaccttg
     4321 gttccgagtg ggtaaggctt aggcaatcga atagtgattt ggtccatcga aaccctgccg
     4381 acaattgggc aagcttggcc atctaccaag acagagaaat tttgcatgtc tcttgtccat
     4441 ccatctgcat acccgattgg cacggtcgcg atgacttgct cgctatccgc ttgataagtt
     4501 gctccatagc ccatgcaagc tccagctgga actgtcttga catgaaccag agcagactcc
     4561 aaggtcaagg ccggtatcaa atcataaggc aaatccaaga ccgctccact tggattgagg
     4621 ccatacatgg catctcccat acgaaccgca ttgaaaatag tctctacatg ccaaagagtc
     4681 gttgcagaat tgctagcatg aaccagctct ggaacttcct tcatactagc taaaatagtt
     4741 ttaaaccgtt ctaactgggc attaaaatag tcatctgatt cctcatcagc agtagcaaag
     4801 tgggtaaaga ttccttcaac acgaacaccg tgttgttgga gcaaatcttg agcctgctca
     4861 acctcactgg cctctctaaa accaatccgt cccatccctg aatcaatctt gaggtggact
     4921 gtcaatccag ttaggtccac ttccttatct aagagtgctt gaatccactc cagtccagcc
     4981 actgtcaagg tgaagtcata ttctttagct agagcaacag cttcgatttc agaaactcct
     5041 aaaatgagga ttggcttgct gagtccagct tgtctgagtt caatggcttc atcgatattg
     5101 gaaacgcaaa agccatcaac atcatcttga attgccttgg caacggcaac agctccatgg
     5161 ccataagcat tggccttgac cacagcccac ttgagcgttc cttgagggat atgagccccc
     5221 atttgctgaa tattttgtcg aatagctccc agatgaatca gaaccttggt tggtctatgt
     5281 ggactagctt tcatgatttt cctccaaaat gacactggct gtcacaaact gatcggtgtg
     5341 gctgatagac agccaaatct ttcctgaaaa tggtgcctga ctaaaataag gcgccccacg
     5401 ttcattgttc aagacttcca aatcctgaaa accgagcttg ctaatgcccg ttcccatagc
     5461 cttggaaaag gcctccttag ccgaccagcg accagctaaa tattctattt gcctgcgtcc
     5521 tttgagactg gtgaagcgct ccatttcctg agcggtcagt acacgcttag caaatccttc
     5581 atgtcgtgta actgcgcttt ctatcgaagc caattcttcg atgtcaattc cgtgtccaac
     5641 tatcattctc atcaaaagga gttgagattc cccaactcca tccttttcac ttattttgtc
     5701 aaggtaacat aaatctcttc taccaaggcc tctgtatttt cccaacctag gcaagggtca
     5761 gtaatagagc aaccaaagac ctctggttgg ttttgacgac catctgctag gtaagattca
     5821 atcataaatc ctcgaaccgt ctttttaatt ttctcattcc aatcacgatt ctgcaaggtc
     5881 tggcgaacaa ttcgaatctg ctccatatat tgcttgcctg agttatcatg gttggtgtca
     5941 atgaggataa aaggattttc aagtcccatg gtttcatagc gttcaatggc ttggagtagg
     6001 ttttcatagt agtaattcgg catataattg ccatactcgt tgactgctcc acggaggata
     6061 acatgggcca aaggattacc tgatgtctca acttcctgcc catgataaag gaaggtttgc
     6121 ttgttttgag cagcatagat ggcgttaaac ataacaccca aatttcctga ggttggattt
     6181 ttcatcccta ctggtgcatc aatcccagaa gccacaaagc ggtgctcttg gtcttccaca
     6241 gaacgagctc caacggcatg gtagctgacc aagtcatcca ccaagatcag atttgacgga
     6301 taaagcatct catctgccgt tgtcaaacca gtctctgtaa tcacgcggta gtgcaactgg
     6361 cgcacagcct gcaagccatt aatcaggctt ggagccttag aagtatctgg ctggtgaact
     6421 aatcctttat agccgtctcc attggtacga ggcttagcag tatacacgcg catgaccatg
     6481 aaaatcttat ccgctacctt cttttgcaag gcggataaac ggcgagcata ttccaagacc
     6541 gcctcttcat tatcagaaga gcaaggacca atcaccaaga gaatacggtc atcttcccct
     6601 gaaataatat ctgccaattc cctgtcacgg ctttccttga gtctcaaggc ttccgcagac
     6661 aattgggttt cagccttgat gacttccata tcgatttctt gacctttttc aataaatgcc
     6721 atcttattct cctaacgttt tgtaaatttc tctgacaaga gcttctgtgt tatcccaacc
     6781 caggcaaggg tctgtgatag acttaccaaa tacttctggc tcattttgtc gaccatcttc
     6841 cagataagac tcaatcataa aaccacgaac gaactgctta attttttcat tccaagcacg
     6901 gttaatcaag gtctggcgga caattcggat ctgttcaata tactgcttac cagaattgtc
     6961 atgattggta tcaatgatga taaaaggatt ttccaagccc attttctcat actgggcaat
     7021 ggtatcaatt aaattgtcat aatagtagtt gggaatattt tttccatact cattaagagc
     7081 accacgaaga atagcgtgtg aaagcgggtt cccagttgtt tctacttctt ttcctaagaa
     7141 aaggaaactt tgtttgtttt gagcagcata aatcccatta aacatgacat tgagatttcc
     7201 agaggttgga tttttaaaac cagtagaaaa tcctgcccca cttgccacaa agcggtgttg
     7261 ctggtcttca actgaacggg caccaactgc catgtaagaa atcaaatcat ctacaagcgg
     7321 aaggttttca ggataaagca tttcatcagc agttgtcatc cctgtttctg tgatgacacg
     7381 atagtgaaga tggcgaacgg ctttgattcc attgataaga ctaggcgctt ctgtcgcgtt
     7441 aggctggtga atcaagccct tatagccatc tccgttggta cggggtttgg cagtataaac
     7501 acgcataacc ataaagatac gatctgccac ttcttcttgt aggactgcca aacgcttagc
     7561 gtattcaagg acagcttctt cgttgtcaga tgagcatggc ccgattacca agagaattcg
     7621 ctggtcttct ccacgtataa tggcttctag ctcttgatct cgctgtgatt tcctctccaa
     7681 agcctgacct tctaattttg acaaggcacg aacttcttct atatttattt tagagctttt
     7741 tgctgtaaat accataactc atctccttat aaagcaaacg gatacccagt aaaaatttac
     7801 ttttcacaag atatccgcct ctaaactatc tcattttatt gtcttttacc gtgacagttt
     7861 ttaaatttct taccagaacc acatgggcaa agttcattgc gtccaatctg gctcaaatcc
     7921 aaatcttctg gcatacttgc ttggtgagca gcgatattgc gagtcgctgt tgtactgata
     7981 tgacgttctg cctgtggtct ttcttgttca tgaatttgtg ctttcatcat caagcgtgtc
     8041 acatcaaact caatcgaacc aatcatatca ttaaacatac ggaaaccttc tgcctgatac
     8101 tcaacaacag ggttgttctg agcatagcca cgaagtccaa ccgcgttacg caattgatca
     8161 agggcatcga tatgatctgt ccacttgtta tccaccactc gtagaatcaa aactttttgg
     8221 aattctttaa ctgcttcttc atcgcgtagt tttgaaacct gactatcgta aaccttcaag
     8281 gcacgttgga aaagctcttc cttgatggcc ttatcagaca agcctgacaa gtcttccatc
     8341 gtaatagaat cttcaggaag caagttgtac ttagcgaagt tcaaaattgc ctctagtttc
     8401 tcatcttgtt tagcacgcgc atgaccgtca acgacacgac caatcgtgcg tttgatcatt
     8461 gcctgaattt caggtgccaa gtcacggtct gcagtaatga catcataacg ttgagtatag
     8521 ataatctcac gttgttcacg catgacatcg tcgtattgaa ggacttgttt acgggtatcg
     8581 tagttatttc cttcgacacg tttttgcgct gcttcaacct gacgcgtcaa catgcgagac
     8641 tcaatcgcct cttcagacat gttgagacgt tcaaagattc ccttcaagcg ttcagaacca
     8701 aaacgtttca tcaaatcatc ttcaagagat aggtagaatt gtgactcacc tggatctcct
     8761 tgacgacctg aacgtccacg aagctggtta tcgatacgac gactttcatg acgttctgta
     8821 ccaataacac aaagtcctcc aagttcacga acaccttcac caagcttgat gtcggtacca
     8881 cgacccgcca tgttggttgc gatggtaacg gcaccacgtt gaccagcatt catgatgatt
     8941 tgggcttctc tatagtggtt tttggcattc aagacttcgt gaggaacacc agctgcaacc
     9001 aatttcttag aaatgtagtc actagtttca accgctactg taccaaccaa gacaggttga
     9061 cccttttggt aacgagcctt aacgtcttcg acaaccgctt taaacttaga ttcgatactt
     9121 gcataaagaa ggtctgagtg gtcaatacgt tgaacaggac ggtttgttgg gattggaata
     9181 acacgaatgt tgtagatttc acgaaattct tcttcctcag tcttacctgt acccgtcata
     9241 ccagacaatt ttttgtacat acggaaaagg ttttggtacg tgattgaggc agatgtcttg
     9301 gtttcatcct ggattggcac accttctttg gcttcaatag cttggtgcaa tccatcagaa
     9361 taacgacgac cttccatggt acgacctgta aattggtcga caatcaagat ttcttgctct
     9421 tcgctcacca catagtcaat atcgagaagc atgatgtagt tggcacgaag ggcgttatcg
     9481 ataaagtggg tcaaagccac gttttcgatg tcatagaggt tttcaagttt gaagtagctt
     9541 tcagccctgt caatccctga atcagacaaa ccaatagtct tagactgcac atcgatgatg
     9601 tagtcatctt tgttcaaaga ttttacatag tggtctgcca tgtgatacaa ctgactggtt
     9661 tcaaccgcat tggcacctga tacaatcaaa ggtgtacgag cctcgtcaat caagatagag
     9721 tcaacctcat cgaccaaggc atagttaagc ggacgttgta ccatgttttc agcgcgaacg
     9781 accatgttgt cacgaaggta gtcaaatccg atttctgagt tagttgagta agtaatatca
     9841 cactcatagg cttctttttt ctccattgga gatttggtag ccaagttaat ccctactgac
     9901 aaaccaagcc aagagtacaa ttcacccatc tcagtcgcgt cacgttctga caggtattca
     9961 ttaaccgtaa ctacgtgaac ccctttacct gaaagggcat tgaggtatac cggcatggtc
    10021 gcagtcaagg ttttcccttc ccctgtacgc atctctggca cgtcaccatg gtgaagaaca
    10081 atccccccca tgacctgaac cttataaggg aagagaccta ggacacgttt ggcaccttca
    10141 cggacaaccg caaatgcttc gtaaagcaat gaatccagtg attctccatt ttgataacgt
    10201 tccttaaatt caactgtttt tgcttttagt tggtcgtcag tcaaagcagc catttggtct
    10261 tcgtatttga aaaccttgtc agccatcttt tccagacgac ggatttctcc tttatcattt
    10321 tcgataattg tttttaaaat attagccatg tttttcctta ctttaaattc cgaatatttt
    10381 agaatgttcc tttaatttta gcacaattac tgattatttt caaggaagaa tccccatttt
    10441 gaagaggaaa aagaggttag ttttcaagct aacctctccg acttttatga ctgtttaatt
    10501 gccaaaaatc ggcaaaatgg caaatgtgat aaataagtta atccaaagag aaagacagca
    10561 aatcagttca aaaacaaaga gactgacttt cttggacagc aaggccatga gaatggacag
    10621 aattccaaaa gctagcaaga ttttctgtat gatgaagatg tcaatcctta tccccagaag
    10681 tggtttatcc caagggataa agaagaaaga cagccagatc agcagaacta aaccaatata
    10741 aaccttggaa tagcgtgtaa taaatgattt tagatgtgcc ataagccatc tcctaggatt
    10801 gtatatcctt tacatttgta tatgtccatt ttcgacaact aatacatctg tacaaaggtc
    10861 tgaaatatct tccgatatgt gcgacgtcag gataaccaga ccattttctt ttttcaggta
    10921 agataaaatg acctgtttgg ttaacctcac actcttctca tccaaagcat tcataggttc
    10981 atcgagaaag agtatagaag gagaggaaat aaaggcttga atcaaggcca ttttttgctt
    11041 tgttcccaag gataaatgcc ggtattcaac gtcttcaaat tcctgtaaat catagtattg
    11101 aatccaatag gcaattcttt tttccgtaac tttagatgaa aaatacctta acagttccaa
    11161 attttctctc agggataaat gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc
    11221 ctgaatataa tgatttttta tcccgtaaac tttaccatct tgaagaactt ttcctttgtc
    11281 aagcttaata taaccagcaa gtacctttaa aagaaccgtc ttgccagatc cattatcacc
    11341 tttaagtcca taaatttttc ctgattgaaa caccaaattc aactgattta aaataggtct
    11401 tttcccataa attttctgtc catttataat ttcaagtttc atcgtttatc ctttcttaaa
    11461 tttctcttcc aagcgactaa caatcaacat aactaataag cttaagagta gtaaatacac
    11521 tgttacaata tgatccatca tccattcttg tcccacaaat gctaaaaaat agagaaaaaa
    11581 ggaaaaacca gcgcccgcac taatcagtgc tatcagataa gacagtagta agtacaacat
    11641 cattaactga gcaagtaaaa agaaaagtgc gactgttttg aaatgaattc ctagcggaag
    11701 taaaccaagg aaccagacaa gtaaatcttg agtaaaaaat ttagaaatga caaccaatcg
    11761 tttccttgta taatcgaaaa aggagcttga ttgatagcga atcaagtgat ggtaatggtc
    11821 tgccaaatca ctttcaagta aaatgacaga gagccatcct accatgaaaa gcgaaaggtt
    11881 taacaagagt ttggggattt ctaaattcgc ttcagaatag tcattatagg aaaaaattga
    11941 aatcaattct ctcttgaaaa agataacagc atcctgcttt tgaaccgctg ttgacaatag
    12001 atagtttatc aaaatcatca tcagaactat acgaagtagt aaaacaatct ttctctttag
    12061 caaaatattg ttaaaattct taaacattat cttcatattt ttcaagcacc atataaggga
    12121 caatataaag gatataagga gtaaagagtt tcatcaaact tacatcccca tagctagctt
    12181 gcatcaaact cgtcatagga accatatagt aaggcaaggc actatagagc agcatagaac
    12241 caagccaaag aaacatcaaa taggtgattg ccgaacgagt cacattcccc acataatcaa
    12301 ctatttgtaa aaaatagatt gcattgatga aaataccgat tagtaggaca caagtaaaga
    12361 acaaatagct ttttatctct ccatctagga gtctttgtaa accacttcca tcagaaaata
    12421 gagaattcca tccaagagga gaaaaagtcc caaggaaata ggttataatt gcaattatca
    12481 gcacagtcac taaatatatc aaacaaggga tacttgcaac ttgcaaagtc aactttcttt
    12541 ttaacccttg atagctcact tctcttccaa tactcaatcg taaaacttta tttttcagct
    12601 caatatattg aaaacctagc aaaacaatga tgattggaat aataaatgat tgataaaaac
    12661 ctagattgaa ctggagaata cgaaaatcta atgctgattt taataagtca tttttaattg
    12721 cttgtccatc gaatttagct agatcgggcg catgaatatc aaaaaagaaa taagtcatca
    12781 aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag caagacataa acaaatttat
    12841 gccttgcaaa agttaagaga ggaatcttca taaattatac ctactttacg aattaatttg
    12901 gtgaccaact acctgaaatg gcagctgata aatcccacca attttgtctt gccatatctg
    12961 ctgcataaac atagccaacc gttgcccaat taccatgagt tgaacgagta ccacaggttg
    13021 ttaacgattc tccactacga gcttctccat tagaatttac tatacgatgc ttaacagtca
    13081 tgggatgtaa atttctacaa ggatttaagt tcatgatata ttccgcacct tcattttctt
    13141 tagtcaaata acctgttctc ttataactgg tagtaataac aaaattacta aaagcaccta
    13201 tctgatttgc ttctacgaaa gtagttccaa cagcacttat cattaaaaca ggaataacca
    13261 ttttcaataa tttcttagtt ttcatttttt attcaagaag attccttata acttctattt
    13321 taaatataga cttattctaa acgatggtat atcatacaaa ttcctccttt acttattatg
    13381 tatagactct aatttcttta tccccaaaac catgtttcaa accagataag ttgaatccaa
    13441 ctccaaatca aaaatccaga gtttttcggt aaattcttca aatatttttt aaagcccatg
    13501 actttttccc tcctttttga tataataata ccaccttttt ctacgttttt tataaatgta
    13561 gaaaatattc acatttacct aggaggaaca atatgagatg ggattatgaa cagattttta
    13621 aagaaattcg aaagtcaaaa ggattgaccc aacaagatgt atgtggacaa gtcatacatc
    13681 ggacaactct aacaaatatt gaacacggta aagttattcc cagttttgaa aacatggtat
    13741 ttcttcttga acaaattgat atgagcttgg cagaattcaa gtatatatgc aacgaatacc
    13801 atcctagtaa aaggcgagat attattgtag agagccaaaa tccgtctact tttcaagata
    13861 ctagaaaaat ggttgaactc actgagaaat gtcaaaaata tcttaagaca catcacgatg
    13921 ttcctattca aaatatctat cgtcatacaa aaattgtcac agagttacga actaaaggat
    13981 tcaaaaacaa ccacgtcttg aaagatttgt ctgaagaaat ttgggactat cttgaaccta
    14041 tggatacatg gtacattagt gatttgaaat tgcttggaac cattctcttt ttctttcctt
    14101 ctgaaaatct tccccttctt attgatagaa ttatgaaaac catcgagaaa tataaatact
    14161 tccgagaaac aaaagtattt ttatcatctt ttttagccaa tctctccact gtatattttc
    14221 aacatcattt attcaaagaa tgtgaaacaa tcaccctaca acttttggta ttagcagaag
    14281 aattaaaaat atacgatatt cttggattct ctcaagtacg cttgggaata ctacaacata
    14341 actccgattt gattgataaa ggaataactt tattacgact aaccaaagaa gaggcattag
    14401 ttaaaatact cgaaaaagaa attaatgatt tttcaaacct ataatttgta ataactctca
    14461 tcattt
//
LOCUS       DAVKZI010000046        14326 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKZI010000046 DAVKZI010000000
VERSION     DAVKZI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.047"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(2..1852)
                     /locus_tag="VXB18_001768"
     CDS             complement(2..1852)
                     /locus_tag="VXB18_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0382933.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIILLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(1894..3051)
                     /locus_tag="VXB18_001769"
     CDS             complement(1894..3051)
                     /locus_tag="VXB18_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0382934.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            3109..4192
                     /locus_tag="VXB18_001770"
                     /pseudo
     CDS             3109..4192
                     /locus_tag="VXB18_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
     gene            4331..4657
                     /locus_tag="VXB18_001771"
     CDS             4331..4657
                     /locus_tag="VXB18_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0382935.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4644..5237
                     /locus_tag="VXB18_001772"
     CDS             4644..5237
                     /locus_tag="VXB18_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0382936.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            5230..6141
                     /locus_tag="VXB18_001773"
     CDS             5230..6141
                     /locus_tag="VXB18_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0382937.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6204..7268
                     /locus_tag="VXB18_001774"
     CDS             6204..7268
                     /locus_tag="VXB18_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382938.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7446..8306)
                     /locus_tag="VXB18_001775"
     CDS             complement(7446..8306)
                     /locus_tag="VXB18_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0382939.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(8581..9567)
                     /locus_tag="VXB18_001776"
     CDS             complement(8581..9567)
                     /locus_tag="VXB18_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0382940.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9839..11314)
                     /locus_tag="VXB18_001777"
     CDS             complement(9839..11314)
                     /locus_tag="VXB18_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0382941.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     IWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEVLNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11572..12495)
                     /locus_tag="VXB18_001778"
     CDS             complement(11572..12495)
                     /locus_tag="VXB18_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0382942.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12509..13438)
                     /locus_tag="VXB18_001779"
     CDS             complement(12509..13438)
                     /locus_tag="VXB18_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0382943.1"
                     /translation="MNKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            13970..14194
                     /locus_tag="VXB18_001780"
                     /pseudo
     CDS             13970..14194
                     /locus_tag="VXB18_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4311 a         3065 c         2634 g         4316 t
ORIGIN      
        1 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
       61 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      121 ccttaccaac gaaaatctta tccataactt gattgtcaac gagttcggtt gataccaaga
      181 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      241 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      301 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      361 ggctagcttc tggaatggtc ataaagtaac gggtcatgcg gaagtctgtc accgttacag
      421 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      481 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      541 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      601 tcgaaatcat aaccatctta gacactttag cttcatcaac agccttagca acattgtaag
      661 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      721 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      781 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      841 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag ataatgcgtt
      901 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
      961 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1021 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1081 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1141 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1201 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1261 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1321 attcactggt tggatgttgg taactatcca taaaaagagc cccaccatca ccggcaccaa
     1381 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1441 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1501 tgaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1561 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatgc
     1621 tcgcgttcaa cccccaaaaa ccaatcatca attgatagaa caggaaggcc aaactcgtat
     1681 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1741 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1801 tatttaaaat ttccaccaga tcaatcacat aatctgttag ttttttattc atagaaatct
     1861 actcctcctt aaaagagttt tactatattg ttattatagc atattttgat ttatttggct
     1921 tattttatcc aaataaatta ttgttccctt gtactccttc ttccatttaa atcctctaat
     1981 taaacctaca atcgtcccaa agccataagc aaagtgaatg gaaaataaaa gaaagggcat
     2041 cacaattaga aatccatttt tatgttttaa taaagtcagc aaagtgagta gtgacaaaag
     2101 tagaaaatag gcacctaata gtaaagttat gaatacgaat gtgatcggta acaatgctag
     2161 actaaacaca agactcaaaa caaataaaca aggaacatag tgaaataatg ataaacactt
     2221 aaactgaaca tgacttgtca agccaatcca caaaccattt gaatactttt gatgcagcat
     2281 tttcttgaat gttggtcgaa tatactgata agatagaata cttgggctat agcggatttt
     2341 ataaccatgt tctcgaattc tataatgaat atcattatct tcagttcggc caagttgctc
     2401 atttactaaa ccaaccttct ggaaaacctc tcgtttatac atcccatgaa aaatagaaga
     2461 aacatatcta tcctcggaac tatttcgata attggcaata ctacttccaa acatattttc
     2521 ctcaacaaga tgcaaggtct ctgcccattt tccttttcct tcgacaatcg tcggtctagg
     2581 ccccccacag acaaattcac cttgttgaat aatagccaca ttgttcatta caaaactctc
     2641 agtaactttt gaatgagcat caatttttaa aataaggtcc cctacagaat gtttaactcc
     2701 caggttaaaa ccactagctt gatttttctt aggattgtta tacaatctaa ttgagttaaa
     2761 ctctgtatct tcctttataa attgctgaat gatagctgtg gtcccatctg tggacatagc
     2821 atttataaat agaatttcaa tattctcttt aggataggtt tgatttttta agtcttcaat
     2881 tagaccaggc agatattttt cttcattgta tgcactgatt acaatggata cgagaagact
     2941 ttcaacattt tgagtcacta ctactctcct gaatttttcc ttccaccatt ctatcataat
     3001 tttcaagact ttcccatttt tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa
     3061 aaagccttaa aataagctgt tattaaaatc agctagaaga ggtattatat gaaaaagcaa
     3121 tcactctttt ttgttccagg tattatcctg attggtgttt ccttgcgaac tccttttact
     3181 gttttaccca ttattttggg aaatatttcg caaggtctgg aggtagaagt tagttcgctt
     3241 ggtgtcttga ccagcctgcc tcttcttctt gaccatcggc tcacttattc gactaatcaa
     3301 tctgcccctg ctctatctag gaaccttgat ggttggggca agtgtcgcag tcatcaatgt
     3361 cctgcttcct agtcttatcc aagccaatca accaaagaaa attggttttc tgaccacctt
     3421 atatgtaacg tctatgggga ttgcaacggc tctggcttcc tatctagctg tgcccattac
     3481 acaagccagt tcttggaaag gacttatcct tctcctcacg ttactctgtc tagcaacttt
     3541 tttggtctgg ctcccaaatc accgctataa tcatagacta gctccacaaa ccaaacaaaa
     3601 aagtcaaata aaggtcatgc gtaataaaca ggtttgggca attattatct tttcaggttt
     3661 tcaatccttg atcttttaca ccgtcatgac ctggttacct accatgtcta tccatgcagg
     3721 tctatccagt cacgaagctg gcttgctgac ttctatctta tctctgatta gcattccttt
     3781 ttcaatgacc atcccaagcc tgacaaccag tttatctact cgcaaccgtc agctcatgct
     3841 cactctggtt tcactagctg gtgtggtcgg catttccatg ctctttttcc caatcaataa
     3901 tttcatttac tggcttgcca tccatctcct catcggaacc gcaaccagtg ccctcttccc
     3961 ttatctcatg gtcaactttt cactcaagac aagcgcccct gaaaagacag cccaattgtc
     4021 cggcctatct caaacaggag gctatatcct agcagccttt gggccaaccc tctttggtta
     4081 cagttttgac ctgttccact cttgggtacc atctgtagct gccctcttgc tcatcgatat
     4141 cctgatgact gtggccctct ttacagtgga cagagcggat aagatccttt aaacttctag
     4201 ttttagctag aagtttttta tatataaaaa ttttacacat ttctcttgac agggctttct
     4261 tttagatgta caatgtatgt gtagaaaaat tatatataaa aatcttacac attagaaaag
     4321 gaggtttccc atgtactttc caacatcctc tgccttgatt gaatttctca tcttggccgt
     4381 actggagcag ggtgattctt atggttatga gattagccaa accattaagc tgatcgctaa
     4441 tatcaaagaa tctacactct atcccattct caaaaaattg gaaggcaata gctttctgac
     4501 aacctattct agagagttcc aaggtcgcat gcgcaaatac tactccttga caaacggtgg
     4561 tatagagcag ctcttgaccc taaaagatga atgggcactc tatacagaca ccatcaatgg
     4621 catcatagaa gggagtatcc gccatgacaa gaactgaata cctgactcag ctagaactct
     4681 atctcaagaa actacctgaa gctgaccgta tcgaagccat ggactatttc agagagctct
     4741 ttgacgatgc tggagtcgaa ggagaagaag aactcatcgc tagtttggga actcccaaag
     4801 aagcggccca cgaagttcta tccaatcttc tcgataaaaa aatcaatgaa gcacccgctc
     4861 aaaaaaataa ccgacaaatt ttacatatcg ccttgttagc cctccttgca gcacctatcg
     4921 gcattcctct gggaatcgcc atcctcgtga ccctgttcgc aatccttgta gccgctttga
     4981 ctgtcattct ggctttcttt gcagtttcca tactgggtat catcggcgga ttcctatttt
     5041 tagttgaaag tttcactgtc ctcgcccaag ccaaatcagc ctttatcttg atttttggtt
     5101 ctggtttact ggctatcggt gcttcttcgc tagttttact aggcatttcc tatgtagctc
     5161 gcttcttcgg tctactcatt gttcgcctgg tacaatttgt tcttaaaaaa agaaagagag
     5221 gtaaccagca tgcgtaaatg gacaaaagga tttctcatct ttggtgtggt gactaccgtt
     5281 atcggcttta tccttctttt tgtaggtatc caatctgacg ggattaaaag cctactttcc
     5341 atgtccaaag aacctatcta tgatagccgt acggaaaagc taacctttgg caaggaagtc
     5401 gaaaacctag aaattactct ccaccaacac gcgctcacca tcacagactc tttcgatgat
     5461 caaatccaca tttcttacca tccatctctt tctgctcacc atgatcttat caccaatcag
     5521 aacgatagaa ctctgagtct cactgataag aaactgtctg aaactccgtt tctctcttct
     5581 ggaattggtg ggattcttca tatcgcaagt agctactcta gtcgttttga agaagttatt
     5641 ctccagctac caaaagggag aactctaaaa gggatcaaca tctcagccaa tcgcggacaa
     5701 accaccatca taaatgctag ccttgaaaat gcgaccctca atacaaacag ctatatcctc
     5761 cgaattgaag gaagtcgtat caaaaacagt aaactcacaa cgcccaatat cgttaatatc
     5821 tttgatacag ttcttacaga tagtcagcta gagtcaacag agaatcactt ccacgctgaa
     5881 aatatccaag tccatggcaa ggttgaactg actgccaaag attatctcag aatcatccta
     5941 gaccagaaag aaagccaacg aattaactgg gacatctcaa gcaactatgg ttctatcttc
     6001 caattcacaa gagaaaagcc tgaatcaaga ggtacggaat taagcaaccc ttacaaaact
     6061 gaaaaaaccg atgtcaagga tcaactcatt gcgagatctg atgataatat tgatctaata
     6121 tccacaccaa gcagacgttg acaaaaacgc ttacatctgc tactatggaa gcatatttat
     6181 ctaactaaaa aggaggttct accatgaaac aagaatggtt tgaaagtaat gattttgtaa
     6241 aaacaacaag caagaacaag cctgaagagc aagctcaaga ggttgcagac aaggctgaag
     6301 aaacgatagc cgatttcgat acaccaattg aaaaaaatac tcagttagag gaggaagtct
     6361 ctcaagctga agtcgaattg gaaagccagc aagaagagaa aattgaagct cctgaagaca
     6421 gtgaagcgag aacaggaata gaagaaaaga aggcatctaa ttctactgaa gaagagccag
     6481 acctttctaa agaaacagaa aaagtcacta tagctgaaga gagccaagaa gctcttcctc
     6541 agcaaaaagc aaccacgaaa gagccacttc ttatcagtaa atctttagaa agtccttata
     6601 tccccgacca agctccaaaa tctagggata aatggaaaga gcaagtgctt gatttttggt
     6661 cttggctagt ggaagcgatc aaatctccta caagtaagtt tgaaacaagt atcacacaca
     6721 gttacacagc ctttctcttg ctcattctgt tttctgcatc ttcctttttc tttagtatct
     6781 atcacatcaa acatgcttac tatggacata tagcaagcat taacagtcgc ttccctgagc
     6841 agctagctcc tttaactctt ttttctatcg tctctatcct agtagcgaca acactcttct
     6901 tcttttcatt cctcttgggt agtttcgttg tgagacgatt tatccaccag gaaaaggact
     6961 ggacgctaga caaggttctc caacaatata gtcaactctt ggcaattcca atcttcctca
     7021 ctgctattgc tagtttcttt gctttctttg atagcctacg atttacagct ctcttgtgtg
     7081 tgattagcat tggaatcatt ctgcttgcca gtctccatat cattacaaga ccaagtcaag
     7141 caagtgaaac cgactccttc tatcaattat tcttgtctgt ccttgtgaac ggagttatta
     7201 tcctcctctt ctttgtagct gaagtggcac tgattggaga ttatcttcgt atcttggcct
     7261 ttctttaaac ttcatactct tcgaaaatca aattcaaacc acgtcagctt cgccttaccg
     7321 tactcaagta cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtagca
     7381 atcctgtcat ccttggcagg attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt
     7441 ctgctttact cttcttgtgc taatgcttta aaatctttgt ctaatatggg ttgcacttct
     7501 atttgattgg cgtctagttg gtggtaaaaa gataggggta atacctctaa gaattttgca
     7561 tagtccaagc gggcaatggc ttcatagtct tctggtttag agccatctcc tgtgatttga
     7621 accaagtcaa tctcccactg cacttcctta tccaccaatt gctcaatata ggctgcagga
     7681 acaaacggtt ctctcggtaa aactgtcttg actccttgag ctagatggta aacgccatgc
     7741 acttttcctt ctccatcctg atagaaggaa actctcgcaa agtaggcatc tgtctcttga
     7801 accgcacgca cacgcgcttc aaactgagcc aagccatctg cctctaaaaa gcttttcaag
     7861 ttctcacgac taaagaaaat aggattaaaa attccttggc aaatcgtaaa acgagctaca
     7921 gggtctgcta gataggcttg aatacttgct tggaaataag cttcaaaatc aaaaccatct
     7981 agcccttcaa tatcagtccc tgtataagca agcaaagcat ctaaaaatga cttgataatc
     8041 tgccagtctg tctttgttag taggtcagga agatcgacac ggtaagcctt ttgaccatca
     8101 gcataactga ccttaaagag aaattgtgat tgccccacta tcgcacactc gatatattcg
     8161 agacgattaa gaggctgacg gagatagact acatcatagc tatgtgactc caaaccgtct
     8221 agcaatgcca agatcgactt ggcattcaaa atctcttgtt ctcctaaaat gctctgttta
     8281 tttggaataa aaaatgtttt cgccataact ggactccttt gaaatcgttt acatacagta
     8341 taccttattt ttctgaaaga tacaaaaaca aactttatac tcttcgaaaa tctcttcaaa
     8401 ccgcgtcagc ttcgccttgc cgtagatata tgtaactgac ttcgtcagtc ttatctacaa
     8461 cctcaaagca gtgctttgag cagcctgcgg ctaacttcct agtttgctct ttgattttca
     8521 ttgagtatta gatttttgag tacaaagcat agaaaaacag cccctgagga ctgtttgatc
     8581 ttatacagta gctgcttgat ccaagctttc accgatagcg gctaggcgct caatcacttc
     8641 agcttgtgtc aattcatttt ttgaaacata gcggttacgt gggtgaacac ggcactcgtg
     8701 tgagcatcca cgaaggtact tgtcttcatt ttcttctgat gtcaagatac gacggttaca
     8761 gaagggattt ccacagttga cataacgttc acatggtgtt ccatcaaacc agtctttccc
     8821 tacgatggtt gggttgacat ggttgacatc aacggcgata cgctcgtcaa atacgtacat
     8881 ttttccatcc caaagctcac cttgaacttc tgggtcttta ccgtaagttg cgattcctcc
     8941 gtgcaattgg ccgacatctt tgtagccttc acggaccatc cagcctgaga atttctcaca
     9001 gcgaacgcca cctgtacagt aaaccacgac acgcttgtcc atgaattttt ccttgttatc
     9061 acggacccat tgtggtaact cacggaagtt gcgaatatct gggcgaatag ctccacggaa
     9121 atgtcctagg tcgtactcat aatcgttacg tgtgtcaagg acaacggtat ctttatcaag
     9181 aagcgcttct ttgaactctt ttggagacaa gtaagcacct gttgtttcaa gtgggttgat
     9241 gtcattgtca aagtcgttgt cttccaaacc aaggtggaca atttctttct tgtagcgaac
     9301 aaacatcttc ttgaaggctt gttcattttc ttcgtcaatc ttgaaccaga gttcttccat
     9361 acctgggagg ctgtgaacgt agtccatgta tttttgagtt gtttcatagt cacctgaaac
     9421 tgttccgtta attccctcgt cagcgactag gatacggcct ttaaggccga ttgatttaca
     9481 gaaagccaag tggtctgcag caaattgctc tgcattttca attggagtat aaaggtagta
     9541 aagtaagaca cgaatatctt ttgccataag atttgttctc ttttctattc ttaaattttc
     9601 taaatttttt atttatccat actagtatac ctgcttgaga aaacgaatgc aatttatttg
     9661 actggaaatt gtagaggatt ctcgaaattt cctgaatggt taaaataagg acaagagaaa
     9721 acagggatat ctatatcctt gtgccaaaaa aaccactgcc ctccccagac caacctgagg
     9781 aaagcagtga ttcttatttt aggagttagg aatgaataca cgaaatcaat ttagctgatt
     9841 attttttgtt tttcaagaat tcatcgtatt gtttttgcat ttcgttcaat actttttcgt
     9901 aggcaccttc agatttcaat ttttccatca attctggaat cgctttatct gggtctacag
     9961 taccagtgtt gatagctgta tcaaattgtt gcattgtgtt agcaatagct gagatttcag
    10021 atttcacatt gtcagtattg aagataaatc caagcgctgg agattcttta gcttctgcca
    10081 attctttctt agaattttcg atttgttggt ctgtaacgtt ttcgttgatg taaaggatcc
    10141 agttgttacc agtgttccat ccacccatgt gagtgtttcc tttgtagcca tcaagaacgc
    10201 gaacacggtt ttctttacct tcaatttttt cccagttctt gccttctgga ccgtaaacaa
    10261 gaccgttcaa gagttctggg ttggtattca agaggttcaa cacttccatt gatttttctt
    10321 tgttcttaga gttgtttgag atgacaaagt tagcaacttg tgttgtttgg tttttcttga
    10381 tgaagttagt aattggtttg atttggatat ctttgttggc aacacgtgaa agcaagctgt
    10441 taccgtagtc agctggtcct actgtttctt cacgaacgaa ccaaatatct tgttgaaggt
    10501 caaatgaagt atcgcttgtt gcgacatctt ttggaatgta gccagcttca tagaatttgt
    10561 gaagagtctt caagtgttct ttgaaacgag gcacttcgta acggtttaca actttagtag
    10621 tatcgccttc aaggtcgata acgaatggaa gaccgtttgc tactgggtag tcaaagttat
    10681 cagatgggat gaaaacttta ccaatagcaa atggtactac gtctggagct ttttctttaa
    10741 tttgtttcaa gactggctca agagtttcgt aagaagtaac acctgaaata tcgataccat
    10801 atttagcaag gagagttccg ttgaaggcaa agttttgaga tgatgcaacg ttggctgcaa
    10861 ctggaacagc gtaaatctta ccatttacag tattaccctt gatgtaagct gggtcaagtg
    10921 ctttgtaaag gtctttacct tcttttttgt acaattctgt caagtcagcg taagcacctt
    10981 tttgagcatt tacaatatag ttatctgcaa aggcaatatc atagttttca ccagatgatg
    11041 tgataactga cattttctta ccatagtcac cccagccaag gtattggata tccaatttgg
    11101 caccaacttt ttcttcaatg attttgttgg catttgctaa caattcatcc aagttgtctg
    11161 gtttgtcacc gatttggtac attttgataa caggtttgtc acctgaatca gcagcttttt
    11221 tgctgttacc tgtcaaattt ccacaagcag caagacctgc agccagagcg actacactag
    11281 cagatgcaaa agcatatttt ttccagtttt tcatgataaa aactcctttt tttattttta
    11341 aacttataaa caatgtaatg atcttatact caatgaaaat caaagagcaa actagaaaac
    11401 tagccgcagg ctgctcaaag cactgctttg aggttgtaga taagactgac gaagtcagtt
    11461 acatatatct acggcaaggc gacgttgaca cggtttgaat ttgattttcg aagagtatta
    11521 acttcacaca agggaagttg ggaactgaga aatgttattt ctcaataagc actattcttt
    11581 cacaccaccg atagtcaaac cttttacaaa gtagcgttgg aaaaatggat acaaaatcgc
    11641 gattggaagg gttgcaacca caaccatggc catacgacct gtttctttcg gtagagcaac
    11701 tcccagttga ccagtcaagc cgaccgcttt ggcaatgtag tccatatttt gttggatttg
    11761 catgagcaaa tattgcaatg gatacaagtt gtcactcttg atgtaaagaa gggcgttgaa
    11821 ccagtcattc cagaaaccaa gagctgttaa gagcgtgatg gttgcgatac ctggtagtga
    11881 caatggcaaa cagatttgga agaaaatccg ggcttcactg gcaccatcga tacgagccga
    11941 ttctagaatg gcttctggaa tggtcttctt gaagaaggaa cgcatcaaga tgatgttaaa
    12001 tggtgagaga agcattggaa caatcaaggc ccaaacagta tccccaagct gaagcacacg
    12061 agtcaccatg atataacctg gtaccaaacc agcgttgaac aacatactga gcagaacgaa
    12121 gatggtaaag aatctgcgat acttaaaggt tgtccgtgaa atagcgtagg cataggttgt
    12181 tgtgataaag acatttgtca atgtcccaac tacggttaca aagacagaga tgaagagggc
    12241 ttgtaggatt ttatccttaa actgtgccaa aaactcaaaa ccgtctaagc caaattggga
    12301 tgggaagaag ctatagccgt attggaggag gcttttctcg tctgtcactg aaataatgat
    12361 aacgaataca aaaggtagga tacaagagag ggcaatcaaa cccgaaatga tactgaagaa
    12421 gatatctgct ttcttactga aggagtgaat gccgacatta tcaatttttt cttttttaat
    12481 tttctttttt gccatattct cctcctttct agaacaaagc tgagtttgga tcgactcgtc
    12541 ttgcaagcaa gtttgatagg ataaccagaa tcaaaccaac aacggattgg taaagaccgg
    12601 ctgctgcagc cataccgata tctgctgtct gagtcaaacc attaaaaaca tatacgtcca
    12661 aaacgttggt tacattgtaa agctgaccag cattgtgtgg gatttgatag aagagaccga
    12721 agtctgcgcg gaagatattt ccgactgcaa ggatggtcaa tacagttaca agcggagtca
    12781 actgaggaat ggttacgttg cgaatacgtt gccacttgct agctccgtcc actgtcgctg
    12841 cttcgtagta ggttggatca attcccatga tcgtcgcata gtacatgaca ctgctatatc
    12901 caaaaccttt ccaaatacct aggaaaagta ggagataggg ccagatgccc aggtcagcgt
    12961 agaaattgac ttctttgaga ccaagacttt ccaatagatg attgaacacc cctttatcaa
    13021 tatttaggaa ggcatctgta aagaaactga tgataaccca agacaagaag taagggaaca
    13081 acatagaagt ttggaaaatc ttcaccattc tcttagaacg gagctcgctg aggataatgg
    13141 caatccctac agatacaact aaacctagaa agataaagcc aagattgtag aggacagtat
    13201 ttcgtgtgat aataaaggcg tctcttgaac taaataagaa tctgaaatta tcgagtccga
    13261 cccatttact atttatgata ctatctatga aaccattact ggtcatgtgg tagtctttga
    13321 aggcaaccac gttcccaaat actggaatgt aaaagaatag aatcaaccag agtgcccctg
    13381 gcaaaaccat caagagaaag atccagttgt ctctcaaggt ttttgaaaac ttattcataa
    13441 tttcctccct ttttattttg atatccatct aaaaattctt ttttagactt ttgataacga
    13501 ttacattatt agtatactcc tatttacagg ttaggttaaa ctcctaatta tagaaaaaac
    13561 tccacaaatt atgtagcaga tttaaaactt tatcaccact atcaaacaaa tgtcctaaat
    13621 caattgttta ttttatctct attagcccag tgatggcgtc actctgttat aagcatccaa
    13681 caacggggta tactgaaaaa tctccagact agggaactca gcgatagttc ctaatctgga
    13741 gatttttaat atgttattag gcgtttgctt tcaacttagc aataacctct ttaagattat
    13801 caatcaactc tgcttcagta tgctcagagc ctttttcatc tgccaagaac aaaactgctt
    13861 tttgaagttc ttcttgagag ttttcaagga catccttatc tgctgtttca aggtttgagt
    13921 ctgcttacta atactagact aaaatcaaaa agcattatat aacagtgata tgaaatcaac
    13981 taaagaagaa atccaaacta tcaaaacact tttaaaagac tctcgtacag ctaaatatca
    14041 taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa tcgatttcta
    14101 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tccattatat ttcgtctgat
    14161 gggcaaatct tataaagaga ttatagaact tttatagtag tttgaaataa gatgtgaaca
    14221 actctatcag gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt
    14281 atagattcaa tacactatac ttagtggttt agctctcctg ttttct
//
LOCUS       DAVKZI010000047        14196 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKZI010000047 DAVKZI010000000
VERSION     DAVKZI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.048"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            5..1303
                     /locus_tag="VXB18_001781"
     CDS             5..1303
                     /locus_tag="VXB18_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0382944.1"
                     /translation="MSQIYQIKQSDIVIDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYTWANLLVIRRYSNTNKQSTYTDFKWAANQLKVAHKFKFNESL
                     PEITVKETGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYQTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            1315..2784
                     /locus_tag="VXB18_001782"
     CDS             1315..2784
                     /locus_tag="VXB18_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0382945.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILKHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTIQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRSVR"
     gene            2693..4243
                     /locus_tag="VXB18_001783"
     CDS             2693..4243
                     /locus_tag="VXB18_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV0382946.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDVKNEIQDYKKSDKTVSRYNTPKLFSDVSNAWDEIGRGGLSKEQLV
                     DLLESEYELGNFSSDIAKLIGVSSAYIDVSSLATSLVRHGQQYSLDEFMLIKEAVQKP
                     YLILDNSERVEKSIISYVKIPNKDKVIMEAVMVPRDEMLVIHFNKVGIRQVKKNEKNM
                     STLYKKGK"
     gene            4394..4567
                     /locus_tag="VXB18_001784"
     CDS             4394..4567
                     /locus_tag="VXB18_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382947.1"
                     /translation="MDTARIGITNVEFSGTGENDSATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            4712..4924
                     /locus_tag="VXB18_001785"
     CDS             4712..4924
                     /locus_tag="VXB18_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382948.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            5094..5678
                     /locus_tag="VXB18_001786"
     CDS             5094..5678
                     /locus_tag="VXB18_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0382949.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            5685..6527
                     /locus_tag="VXB18_001787"
     CDS             5685..6527
                     /locus_tag="VXB18_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0382950.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDAIKLKTDVAKEWTKGSELGADMVVSGTFGEVAGVQIVRSKKVDEGKGFIV
                     KVSPSQTQTDDANKYGAFVIMLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGE"
     gene            6539..6721
                     /locus_tag="VXB18_001788"
     CDS             6539..6721
                     /locus_tag="VXB18_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0382951.1"
                     /translation="MSLLLRRHYIQEEQVSQYSDLENKTLEELKNLAKEAGIAGAYKL
                     SKAEIVEVLEDLKSEI"
     gene            6711..6899
                     /locus_tag="VXB18_001789"
     CDS             6711..6899
                     /locus_tag="VXB18_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382952.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGGELEITEERYVELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            6901..7212
                     /locus_tag="VXB18_001790"
     CDS             6901..7212
                     /locus_tag="VXB18_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0382953.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIEVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            7193..7531
                     /locus_tag="VXB18_001791"
     CDS             7193..7531
                     /locus_tag="VXB18_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382954.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYVKEAETIRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTYHQVLE
                     LERVRATRGR"
     gene            7506..8021
                     /locus_tag="VXB18_001792"
     CDS             7506..8021
                     /locus_tag="VXB18_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0382955.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            8018..8386
                     /locus_tag="VXB18_001793"
     CDS             8018..8386
                     /locus_tag="VXB18_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382956.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            8389..8802
                     /locus_tag="VXB18_001794"
     CDS             8389..8802
                     /locus_tag="VXB18_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0382957.1"
                     /translation="MLANGITLSYGEAKGTYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVNFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELEFTDGVGG"
     gene            8807..9187
                     /locus_tag="VXB18_001795"
     CDS             8807..9187
                     /locus_tag="VXB18_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382958.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKNKKTSKKKMTVVE"
     gene            9226..9576
                     /locus_tag="VXB18_001796"
     CDS             9226..9576
                     /locus_tag="VXB18_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382959.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKTQERKEKIIDSYR
                     LSQMISNHVSLLLSNDAKIVEFWEYAPELFVEEQQAVELERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            9563..13216
                     /locus_tag="VXB18_001797"
     CDS             9563..13216
                     /locus_tag="VXB18_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382960.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSAAMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIVTDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSSIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAKFAHSVATGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDMFQKAWTGLTNIFSKLGSWFGERWADVTNALSSVSNWFGE
                     MFTNAYNAVKDAFSSIGDFFKGVWDTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            13225..13575
                     /locus_tag="VXB18_001798"
     CDS             13225..13575
                     /locus_tag="VXB18_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382961.1"
                     /translation="MAQLTINGVAVKPPKYFQVGIQDIDGETGRNANGDMMRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            13580..>14196
                     /locus_tag="VXB18_001799"
     CDS             13580..>14196
                     /locus_tag="VXB18_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382962.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTGIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFIDDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESN"
BASE COUNT         4453 a         2501 c         3469 g         3773 t
ORIGIN      
        1 gcaaatgagt cagatatacc agattaaaca aagtgatatt gtaatcgacc tacctaagac
       61 agtaggagct gggtacggac aattctggcg ctcaagaagt ctttatcgtg tagtcaaagg
      121 gtcccgtggt tcgaagaagt ccaagacaac cgctttgaat tatgttatcc gtcttttgaa
      181 atatacttgg gctaacttgc ttgtcattcg tagatattcg aatacgaaca agcaatcgac
      241 ttatacggat tttaagtggg ctgctaatca gttaaaggtc gctcataaat tcaaattcaa
      301 tgagtctttg cctgagataa ctgtcaaaga aacaggacag aagattctat tccgtggttt
      361 ggatgatgaa cttaaaatca catctatcac ggttgatgtc ggtagtcttt gttgggcatg
      421 gttcgaggaa gcgtaccaaa ttgagactga agacaagttc agcacggttg ttgagtctat
      481 ccgtggtagc ttagatgtac ctgatttctt taaacaaatc acagtcacat ttaacccgtg
      541 gaatgagagg cattggctca agcgtgtatt cttcgatgaa gagacgagac gggctgacac
      601 attcgctact acaaccactt ataaatgcaa tgagtggctt gatgaagtcg atatcaaacg
      661 atatgaggat ttgtaccaaa cgaaccccag acgtgctaga atcgtttgtg atggcgaatg
      721 gggagttgct gaaggtttaa tctatgagaa cgtgaccgtc aaggatttcg ataaggatga
      781 attgctacga gattcagcta ataagttatg tatcggtctt gactttggtt ttactcacga
      841 tccaaccgct ttgtgttgtt cgttgataaa tgacacgacg aaagagattt atgtctttga
      901 tgaggcgtat aaagtcggat tgataaccaa agaagttgcg aagatgataa aggacaaagg
      961 ttatcatcgc tcacaaatca ttgctgatag cgctgaatta cgactgattg aggaattaag
     1021 gtcagaacat ggtataactc gaattaaaga gagtcgtaaa ggtaaggata gcattatggc
     1081 tggcgtgtcc aagttacaag gatacgctat ttatgtgcat ccagattgta aaaacatcat
     1141 ggatgaattt tatagttact gctaccagcg agataaagaa ggcaactggt tgaataaacc
     1201 agaggataaa aacaaccact tgatggacgc tttgcgttac agccttcaat gtatcgaagg
     1261 tgggaaagca accgtccgca gacgttctga ttatggtcta tagagaggaa agacatgtac
     1321 caatatttaa cctatccacg ggatggatat gatgagggtt ctttgaagaa agacctgatt
     1381 tacaaattga taacgataca tagcactgaa ggctcgcatt tgaagaagct taaaagctac
     1441 tatttgggtg agcatgctat cttaaaacac acgagacgca acgtgaacgc accgaattac
     1501 aagacggtag ccaatcatgc caaggatatc gcagacacgg ctacgggcta ttttatgggc
     1561 aatcctatca agtataacaa tactgctgac ggtgatatcg atgaactact tacagccttt
     1621 gatggtgctg agattgacca agtagatgct cagaatgctt tgaatatggc tatctatggt
     1681 cgtgcttacg agtacatcta tgctaaagag ggtatggctg agttggattc aactagtatt
     1741 gatccggaga atactttcat ggtctacgat gatagtattg agcggaagcc tttgtttgcg
     1801 gtctattact atgaagtaaa agacgatacg aaagacacta ccaagcacca ggctgaggtc
     1861 tttaccgaaa atctgcacta tcacatggtg ctgagaagta cagattcagg aacaattcag
     1921 agcgaggagg caacacctca caaccttggt caaatcccaa ttatcgaata tcgcaacaat
     1981 cactttgcaa ttggtgacta tgagcaacaa attagcttga tagacgctta taattccttg
     2041 atggggaatc gtgtcaatga taaggaacag gctgtagagt ctatacttgt cttgtatggc
     2101 acgcagttag cagacactcc agaagacgct aaggtagcaa tgaagattct ttctgaagaa
     2161 ggtcttttgg aattgccggg cgatagtgca agggctgagt tcttgaagaa tacgctggac
     2221 gaaagtgcta ctgaaatctt gcgtacagct cttaaagagg acatctacac atttagccat
     2281 gtgcctaatt tgactgatga gaatttcgca gggaatacat caggcgtagc catggaattt
     2341 aagctgatgg gccttgagat gattactaag accaaggaag cgaactataa gcgaggattg
     2401 cgtcagcgta ttgcgatttt tgctcattac ttaggcatga agcagattgc tttagagtct
     2461 cattcaatcg ttccacaatt cagtcgtggt ttgcctaaga acttgttaga aatctctcag
     2521 attgtgaaca atttggaagg caaagtgacc aatagacagc ttatttctct cttgccgttt
     2581 gtggaagacc ctgacgctga gctggaagcc ttggaagaag agaaaaagaa gaacatggaa
     2641 gacatgccga tgttcaacaa agacaacacg aaacccgaag acgaggtaga ggatgaagaa
     2701 tcaggagtat tgggcgaaga ggaaagccaa tctgatttac cagcagatgg acaaggccga
     2761 aaagcaggca gatcagttcg ataaggtcta tcaggaagcc aagacttact tggataagga
     2821 agtcaataag atttttgata agttccaacg tgattatggt ctaagtcagg tagaagctag
     2881 acaagtcttg aagaacatga aagacaagaa aaatctgaat gaacttcgta aagtacttga
     2941 agcgagaccg aatgatccaa atatccaaag actactggct gacttagata gtccggctta
     3001 ttctttccgt atgaagcgtc tagaacgttt gagtgatgat ttagaccgta tgcgtgaatc
     3061 tatctatcat tcagaaaaga caggctcaga cgccttttat agcgacctga tgaaggatag
     3121 ttactacaag gctacctttg acctgcagca gcagacagga ctagcatacg gcttttctgg
     3181 gcttcctgag agcgagatta aacatctaca gtctttcagt tgggtaggag atggaagtac
     3241 gtactcaaca aacatctgga agaatacagg gaagcttaca tcaagcataa aagatgaatt
     3301 actcataagc cttatgacag gccgagatac acgagaaact gcacaagcaa ttgctgagcg
     3361 gttcaatgtg gggcagaacg atgcaaggcg tttggttcgg acagaatcag ccttttttca
     3421 taaccaaatg gagctactca actatgagga agcggatata gagaagtata tctttgtggc
     3481 cgtcttagac aagcgtacat cacgcatttg tcaggagcat gacaatcagg tctatgatag
     3541 ggataaggct gtccctggtg tcaattgtcc gcctatgcac ccttggtgta ggtctactac
     3601 tgtcggatac gatgaggacg cagactacag caagttgaag cgcagagcaa ggaatccaga
     3661 gacaggtaaa gttgagtacg tgcctgccga tatgacttat aaagagtggt atagcaagta
     3721 tgttgcgaaa gatgtaaaaa atgaaataca agattataag aaaagtgaca aaaccgtttc
     3781 aagatataat accccaaaat tgttttctga tgttagtaac gcatgggatg aaattgggag
     3841 gggtggatta tcgaaagaac aacttgtaga cttgctagaa tctgaatatg aattaggtaa
     3901 tttttcgagc gatatagcaa aattgatagg agtaagttct gcttatatag atgttagtag
     3961 tttagctact tcattagtga gacatggaca acagtattcc ttagatgaat ttatgttaat
     4021 aaaagaggcg gttcaaaaac cttatttgat tctagataat tcagagaggg ttgaaaaatc
     4081 aattatttca tatgtaaaaa tacctaacaa agataaggtc attatggaag cggtgatggt
     4141 gccacgagat gaaatgctag tcattcactt taacaaggtg gggattcgtc aagttaaaaa
     4201 gaatgaaaaa aatatgtcga cgctttacaa aaagggaaaa taatgctata ctcttggtaa
     4261 agatagaggt tgagaatctg tcaccaacgc gccacttata gtgggtcgag aaatgcagga
     4321 gccccgacag tcctgcctat ctgtgcacta aacaatcgtt tagtgctttt tttgtactca
     4381 gaaaggattg aaaatggaca cagcaagaat tgggataact aacgtagaat tttcaggaac
     4441 aggcgaaaat gactcagcga cagtgaaatt agagttaaat atttatgggg cggatacgtt
     4501 cagcgcgatt gagttactac ctaaaatatt aaccgacatt cattcattat cgtatgaagt
     4561 tgattgattg tgacattaaa aggagtgaaa acatgtttat atgggattgg gtatcaatcg
     4621 cctttgggtg gttggtattt ttgttgttaa tatttattat tatggccgta atcagcggaa
     4681 taattaaagg tgtaaagaaa ggaacagaaa aatggaagaa tggaaagaaa gatttaaaaa
     4741 agaatactac gaattgaaag aacgattcca gaagttagat atgatgattg ggaaatacga
     4801 aaaagggcaa ctagagtttg aatctaaatg tccgattgat ttgttaaaag gtcagcgttc
     4861 aaccatgtgg aattatttaa gaattctaga acaacgtgca aaaattgaag aaattaaact
     4921 ataaaaatta accgcatcga aatcgaggcg gttttcttat gctctaaccg tatggaatcc
     4981 cgtacggttt ttatattgtc caaactgtgc cgatgacatt aaaagctgta ctgttccgtc
     5041 gccggacgta aagcgagatt atcgagtggc gacgtaatcg ctggaggaca attatgtcag
     5101 aagaaatcaa tgcaactgta tctactgaat caactgagac tgtcgacact caaggaaatg
     5161 ttgattcagt gcaggaagaa aagcacgaac gaactttcac tcgtgctgaa atcggtaaga
     5221 tgctatctgc cgagcgctct aaatgggaag ctgagcaaga agccaaggaa aacgaagcca
     5281 agaaacttgc caagatgaac gctgacgaga aacagaaata tcagttggat cagcgtgagc
     5341 aagaactagc tgaccgtgaa aaggctattg ctcgtaaaga attgaccgca gaagctaaag
     5401 caatgctaag tgaacgtgac ttacctgttg agttagtgaa cgtggttgat ttgacaagcg
     5461 cagagacggt atcgcagtct gtcgctgtat tgcagaaatc atgggagcaa gccgtgcaaa
     5521 aaggcgttca agaaaaacta aaaggcggag ctccaatgaa acaagcgcca gtcgatagtg
     5581 acggtatcac aaaagaagaa tttgctcgta tgggttatca gagtcgaaat gagctctatc
     5641 aaaagaaccc agagctttat aagaaattga aaggataata gaaaatgaca gcaggacaaa
     5701 ctaaattagc cactatggtt aatccagaag taatggcgga tatggtagcc gctaaattac
     5761 ctaaattgat taaatttaca ccgctagcgt atgtagagac aaagcttgaa ggtcaaccag
     5821 gtagcacttt aacagtgcca gcatgggagt atgcaggaga cgctactgaa attgaagaag
     5881 gccaagcaat tacgccagac caattgacta ctaaaaagac tactatgacc atcaaaaaag
     5941 caggtaaagg ttatgaaatt accgatgagt ctcttttgtc aggtcttggt gacccactag
     6001 gtcaagcgac ttaccagctt ggtttagcta ttgccaacaa gatcgataat gatttggtag
     6061 cggtagctaa aactgcaaca caacatatta cagaaactcc aacaactctt gaggcaatcg
     6121 ataaagctct agatatcttt gaggacgaag aagatgcaca gtatgttgct atcatcaacc
     6181 ctaaagatgc tatcaagcta aaaactgacg tagcaaaaga atggactaaa ggttcagagc
     6241 ttggtgcaga tatggttgta tccggaacgt tcggtgaagt tgccggtgtg caaatcgtcc
     6301 gttctaaaaa agttgatgaa ggtaaaggct ttatcgtcaa agtctctcct agccaaactc
     6361 agacagacga tgccaacaaa tatggtgcgt ttgttatcat gctaaaacgt gatgtggcta
     6421 tcgaaacaga ccgtgacatc cttaaaaaga caacggttat cactggcgat gaacactatg
     6481 gtgtttacct atacgaccct acacgagttg taaaattcgg tgagtaagag gtgacgatat
     6541 gagcttattg ctacgacgtc attatatcca agaggagcag gttagccagt attctgattt
     6601 agagaataag actctagaag agttgaagaa tctagccaaa gaagctggca tagctggcgc
     6661 ctataagtta tcaaaagccg aaattgtaga ggtgctggag gatttaaaaa gtgaaattta
     6721 aaatcaaaca agatttctat gattgggaat caaatgtgaa acgactggca ggaggggaac
     6781 ttgagattac tgaggagcgc tatgttgagc tggctgacaa tattgccagc aacggtgtcg
     6841 ctatctcaga tgttcttgag aaaatcctcc ctgaacctga gttcttagaa gaggattgat
     6901 atgtctatag agttgctgaa gaaattaaca ggcgaagaag atactcagct tctcatgttg
     6961 ctccaaacaa gggctacaaa tcttatcttg tcagagacta atcgcacatc tttgacacct
     7021 gctttaagtc ttttaatacc tgaggttgct atcgagctcc acaaccgctc aggagcggaa
     7081 ggagagcgtt ctagaaccga aggtggtata gaagtagtct acggagaaaa cggcctgtct
     7141 acgggccttt tacagcgtat acgtatgcat agactagcaa gggtggcagg ccatgttttt
     7201 gaagcagagt agactgaaac cttatccaat gcgacggttt gaaaagactg tcactgagga
     7261 aggtgtcgca aaagaaggat atgtcaagga agctgagaca atccgtcttg agttgtggcc
     7321 agctagtagt aaactacagt ctgaattgta tggcgagcgt gtcaatgata ttttgaacgc
     7381 aaatgccaac aagtcagcta caatcaaagt gaaagatggt gtgtgtatcg atagccagac
     7441 agaagtgact cacagggtta tttctaaaaa ggtctacaca tatcatcaag ttttggagtt
     7501 agagcgtgtc agggctacta ggggcagata ggctcatagc taaatgtaga cgattggcta
     7561 gtaaaaaaac tggagaggat atcgtcttac gtgcggtaca caatgctact ataaaggttg
     7621 tccaagcaga tgcaagaaga ctcgcaccag cgagagatgg agagcttata actagtatca
     7681 aaactagggc aaaaatggac ggagataagg ctataggcga ggtttacacc aatcttaaat
     7741 acgctcctta cgttgagttt gggacagggc caataggaca agctagccat tcgggtatct
     7801 ctccagaggt cagcgtcact tataagtcta gtccgtggta tgtgcatgaa gaccaaatca
     7861 atgtaggacc ttaccatttt caaaaaattg gggagttcta caagatgtat ggtcaacctg
     7921 cccagcctta tctttatcca gctttgagag acaatcaaga gcgtgtgtct aagaatattt
     7981 cgaattatgt ccgtagaaag ataagagaac aaataaaatg attaatatca agcctgttat
     8041 ttataaagaa ttgcaaaagg tcgcagataa tgtgactgat acttatccta gcgattggga
     8101 gactttccca gtcgttattt ttttagaaga acaaaacaag ccgggtgatt ggtttgatga
     8161 ccaggaacaa aaatcatcta tccgctataa ggtggatatc tttgatgata ccagcactag
     8221 tgagttagct gttaaaatca atcagatttt tgagtcttta ggtttgcgaa gaaccgactg
     8281 ccaagacgtg ccagacccgt ctcatttgag acataaggtc atgcgctttg aaggtgtcgt
     8341 tgatttagac tcagagcttg tttttcaatt tagaatggag aattaaacat gttagcaaat
     8401 ggaattacgc tatcttatgg cgaagctaaa ggaacttata ctaaacttgt tggattgaaa
     8461 gaagtgccag agtttggtat tgaactcgaa aaagtagaaa atactactct tgaagataca
     8521 gtgaagaagt acgagtttgg tattggggac ataggagaac ttgagtacaa gttctcttat
     8581 aataattcaa gcgcaactgc tccttatcgt gtattgcgta aggcagcaga cgacaagaag
     8641 aaactctact tcgagcaagc atacccagac ggtactaagg tcaattttga aggccaagta
     8701 tctgttaagc ttggcggtgg cggtgtcaat gccgttatcg agttcacact taagattgcc
     8761 ttgcagtcag agttggaatt tacagacggt gttggaggtt aattaaatgg cgttaaaata
     8821 cacaacttgg aaagttactg acgaaaaaga gttgaagcta cgtttgacat ctcatcaagc
     8881 tgcaactgtg gaagaaaaaa tcggcatgaa cttgttaaag attttcatgc ctgaagctgg
     8941 cgaagagttc actttaccgc ctttgaaagt tatgctgttg ttagttcatg gagccttgca
     9001 gcagtatgaa catgggtatt cctttgaaga tgtctacgac ctatacgatg aatacgtgga
     9061 caatggggga gaccaaacaa ctttcatgac agaggtttta atgccactat ttgaagtatc
     9121 gggttttact ccacgaggaa gcaagaacaa gaaaacttcc aagaagaaaa tgacagtagt
     9181 cgagtaatct taacagtaac gcagattatt gagaggcttt atcctatgtt tttggacatt
     9241 ggaggcaagc ctcttgattt ttgggatttg acggtgcttg aaatcagaga aatgattgaa
     9301 agctacaacc gtgtcaaaac ccaagagcgt aaagagaaga ttattgactc atacagactt
     9361 tcgcagatga tttccaatca cgtttcttta ttactgtcca atgacgctaa gattgttgag
     9421 ttctgggagt atgcgcctga gttatttgta gaagaacaac aagcggtaga actggaacga
     9481 cagaaacaag cacttttgtt gcataaggaa cggatgcgtg aatttgcaga gagacataat
     9541 cgaaaaagga aggaggaagt aaatggcaac tcttgatgaa ttgaaagtca tgattgacgc
     9601 tgagatagcg cctttcagga agaagatgaa agaagtcgag aatcaggtca aaggaacatc
     9661 tgaccaagtg aagaatgcca ctgccaaagt tcgtgaacag tcgaactcta tcggtagtgc
     9721 gtttggtaag ctagctaagt tcgctggttt tgcaatcctt ggtaagaaat tacttgatgt
     9781 tgggatgtat tcaacgcaga ctgctcttga agtgtcagcg gctatgaacc aaatcaagcg
     9841 ccagatgggc gagagttcgc aatctttctt aaaatgggtt aacgataacg ccaacgctat
     9901 gaacatgggt gtgggtgagg ctactaacta cggtgcggtc tactcaaact tattttctgg
     9961 gtttatcaaa gataccaaca agctaagcgc ctataccgct aagatgttgc agacatcggc
    10021 agtggttgct gaaggttcag ggcgcacgat tacagacgtt atggagcgga ttcgctcagg
    10081 tttgctaggg aacaccgaag caattgagga cctaggaatc aacgtcaatg tggctatgat
    10141 tgagtctact gaagccttta agaagttcgc aaacggacag agctggcaac agttggatta
    10201 ccaaacccag caacaaatcc gccttatggc tattctggaa caggctacag ccaagtatgg
    10261 gaataccttg tctaattctg taaatggtcg tatcagccta tttaagtcgc tgatgaagga
    10321 cgcagcattg aaccttggta actctatgtt accgattatc aatgccatta tgcctgtctt
    10381 gaactctttt gcgatggtct tgaagaacgt tactgctaaa ctcgctgagt ttatcgcttt
    10441 gatgttcaac aagaaagcaa cagtgaaaga tggtgttggt ggagcagttg gagacatggg
    10501 taacgccatg aaagacgctg caggcggagc aggagacctt gctgatgcag tagacgacgc
    10561 tggagattca gcaggaggac ttgctgacaa tcttggagac tccgccaaaa acgctaagaa
    10621 agctgctaaa gagttgctag gtcttttggg atttgatgag attaacatct tgcaaaaacc
    10681 aaaagatgac gacgcaggcg gttctggagg cggtggcaaa ggtggtaaag gaaagggagg
    10741 cggtggcgga cctttcaaag acatcttgcc agaagtcgag ttgaccgaca tggacaacaa
    10801 attcaagagc atttttgatg gtcttggaga taagctcaaa gggttgtttg acctcttcaa
    10861 gaaaggtttt gatgcagcat ttagaccaga aggtataaaa cgcattaaga ctgccttaga
    10921 ccaaatagct aagacaatgg gagaaatcgt cactgaccca agggttgtga atgcctttaa
    10981 ccgaatggct gagaaaattg cttatgcttt agggcaagtg acaggctcaa taaccactat
    11041 cgggctaggt atcggtgttt tccttgccga aagtattgca aatggccttg gaaggcaaaa
    11101 agaacgcatt atcagggcgc tagtcgcttt gtttgataat gttggtaacc tttccgaggc
    11161 agtaggaaac atagctcagg acttttctag tgctttctac gacgtcatta cctcaactgg
    11221 tgcggttcgt atcggtagcg ctattgtgtc aactctgttg agtttgacat ctaccattgt
    11281 tgaagttggt agtaaattag caggaagttt gtttaaaggt tttgaaaaag tcgttgtgac
    11341 aagcgctcct aaaatttcat cagtcttcca aagtttatta gatactgttg cgcctgtatt
    11401 tgagagcatt gaaaggtctg ttaacaaatt tggcgatggc ttaagtcgtg tttatgatga
    11461 acatgtagtc cctgctatta actctattgc taatgctttt aatgggctaa ttgacattat
    11521 tcagattctc tgggagaatt cctggcaacc ttttgctgag tttttatcag gagtattcgg
    11581 tgttagtatt gaaggaattt cagatttatt aggaggtggc cttttagcca ctttgggact
    11641 attggcggat gctattaagt tagtggcaga tggtttcacc gttttttctg actggtgtaa
    11701 agaaaacaaa gaacctatcg tagctttgat aacaacttgg caaacgatta atttcttatc
    11761 atgggcagaa caagctggag gacttgcagg agcattcagc ttgttaggta gtaaggtctc
    11821 ttcgattgtt ggagggatta agaatctagg tcttgctatt aaagcattga catttgataa
    11881 gttagtcagt tttggtgaaa caatctattt gaatacctta tatgcaaaag attttgtggt
    11941 caattcaggt aaaacaattg cacagctagg aaaaactgct ttagaacttg gtaaatcagc
    12001 tctagcatgg actgctcatg cagcgaaaat gggattagca accgcggcga aatttgcaca
    12061 ttctgttgca acaggagtcg ctacagctgc aacatgggct tttaatgcag cgttagcagt
    12121 tttgacaagt ccaataacat ggattattgc agcaatcgca gctttgattg ctatcggtgt
    12181 tttgctctat caaaactggg acaccgttgt tgagtttgct aaaactgcat ggcaaggact
    12241 atgtgatttt atcagtggta tttgtcaagc gattggcgaa tttttcagcg gtctatggac
    12301 gaaactacaa gaaatctttg agccgatagg tcaatggttt ggcgagaaat tccagcaagc
    12361 atgggacgcc attgtaaaca tattctctgg catcggagag tggttctctg gtgtattcca
    12421 aggtgcatgg gacgctatcg ttaatatctt cacaccaatc ggctcatggt tcggacaacg
    12481 ttgggcagat gtgactagtg cgttggctaa tatcggggca tggtttactg acatgttcca
    12541 aaaagcatgg actggcttaa caaacatctt tagcaaacta ggttcatggt ttggcgagag
    12601 atgggcagat gtgactaatg cgttatccag tgtttcaaac tggtttggtg agatgttcac
    12661 taatgcttac aacgcagtaa aagatgcttt tagttctatt ggcgacttct ttaaaggcgt
    12721 ttgggatact gttaaaagta tcttcgtaaa tgctggtcag atggtcggag aggcagtagg
    12781 tggagcgttt aagagtgcgg tcaatgcggt tcttggaacg attgaaaatg tagtcaatgg
    12841 cttcatcgga atgattaatg gagttttagg cgttgtcaga aacttacctg gtctaggatg
    12901 ggttggtagt gtaagcacag ttagcctccc tcgtcttgcc cgtggtggta tcgtcgatag
    12961 tccaacaatc gccatgattg gtgaagctgg taaagaggcg gtcgtaccac ttgaaaatac
    13021 aggatttatc caaacacttg gacgagtagt cagcagtgcg gtagtaaatg ccatggctgg
    13081 tgttagtcca caaggtggat tctctggcga cggcgacatc gttatccaaa tcgcaggcca
    13141 tgagttcgga cgggtagcca tccaagaaat caacaaggaa catgaacgag caggtcaaac
    13201 cttgctcaag atttaggagg ttaaatggca caattgacaa tcaatggggt ggctgtgaag
    13261 cctcccaaat attttcaagt cggtattcaa gatatcgatg gagagacagg gcgtaatgcc
    13321 aatggcgaca tgatgcgtga ccgtatcacg accaaacgca aactagactg tgaatggggt
    13381 atgatgactc agggagaaat aagtcagctt ttacatgctg tatcatctga attttttgag
    13441 gtgtcttatc cagaccccat ggatggccaa gtcacaaaga ctttctatgt cggtgatagg
    13501 acagctccta gctatacctt tactgagaag tttaaacctt ggtctggcgc taaatttaat
    13561 ctggtagaaa ggtaagaaaa tggacgcttt aactagacga caatttgaca gagccatgtt
    13621 tgccaaggaa aggacgctgg ctattcgtgt tggtgattat gcttcacggg atatcaaaga
    13681 ggctagtttt gagtatggct acattaaggg cgatacttat aagcctggtg gaacctgcgc
    13741 tggtagcggt aaaattacct ttaccggtat cattaccacg ttcaataagc tggataccct
    13801 gcaccctgag attggtctac tggttgggga tacctatcag tgggtcaaga tgggggaata
    13861 cttcatagac gatattgaaa ttgaccgaaa ccgcaacaca actacgcttg agcttatgga
    13921 cggtatgttt aaacttaatc gtgagtacgt gacggacttg catttcccag ctgaagtacg
    13981 agaggttatt caggaaatct gcctgaaaac aggcattgag ttagcgaatg actatttcgg
    14041 aatcagcgcg atgcgttatc atattgagca agttcctgag ggcaagaaac tttcctttag
    14101 ggatatgctg agcgctatga ctcagatgat tgggatgtct tgtttcttca acagagaagg
    14161 caagatggaa atccgtgatt tgactgagtc caatat
//
LOCUS       DAVKZI010000048        14192 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKZI010000048 DAVKZI010000000
VERSION     DAVKZI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14192
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.049"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            81..878
                     /locus_tag="VXB18_001800"
     CDS             81..878
                     /locus_tag="VXB18_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0382963.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VXB18_001801"
     CDS             1026..1148
                     /locus_tag="VXB18_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0382964.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1170..1691
                     /locus_tag="VXB18_001802"
     CDS             1170..1691
                     /locus_tag="VXB18_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0382965.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFD"
     gene            1692..2285
                     /locus_tag="VXB18_001803"
     CDS             1692..2285
                     /locus_tag="VXB18_001803"
                     /inference="COORDINATES: protein motif:HMM:NF013237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0382966.1"
                     /translation="MTSGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ASSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYYALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATITHGQLS
                     EKDLEAAGVTPNQIHLSIGLENVEDLIEDLRLALEKI"
     gene            2381..3655
                     /locus_tag="VXB18_001804"
     CDS             2381..3655
                     /locus_tag="VXB18_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0382967.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VXB18_001805"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VXB18_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0382968.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VXB18_001806"
     CDS             4784..5086
                     /locus_tag="VXB18_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0382969.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VXB18_001807"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VXB18_001807"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0382970.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VXB18_001808"
     CDS             5960..7300
                     /locus_tag="VXB18_001808"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0382971.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRSTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLDSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VXB18_001809"
     CDS             7278..7490
                     /locus_tag="VXB18_001809"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0382972.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VXB18_001810"
     CDS             7487..8362
                     /locus_tag="VXB18_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0382973.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFDEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VXB18_001811"
     CDS             8355..9170
                     /locus_tag="VXB18_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0382974.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VXB18_001812"
     CDS             9163..9594
                     /locus_tag="VXB18_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0382975.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VXB18_001813"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VXB18_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0382976.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VXB18_001814"
     CDS             11270..11998
                     /locus_tag="VXB18_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0382977.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VXB18_001815"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VXB18_001815"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0382978.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14104..14184)
                     /locus_tag="VXB18_001816"
                     /pseudo
     CDS             complement(14104..14184)
                     /locus_tag="VXB18_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4196 a         2595 c         3365 g         4036 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cagaatttat ttcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggctt cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaatga tatggaggtc
     1021 accttatgac ttgtgatttt aaatctgaaa ctctacaact acatgctggt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatgttgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaactc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaatacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg aatgacttca gggaaattcc ctcaatttgt tgacgagggt tcaagctgcc
     1741 acaatttgag ctatactcgt gatgtgggtg cagtagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagcctcgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac cctttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttattatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tgacgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca atcactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaatcaa atccacttgt
     2221 ctatcggtct tgaaaatgta gaagatttga ttgaagactt acgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggtt ttgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttacaga agtctagaaa gaggaatgta atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga aagccagtat gctgaacttt tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aggcaggaac tggccttggc
     2521 tgagcaaaag gctatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattgcag agtcaaatcc aaaactttga tacagaaaaa gaattggcca agaaagaagt
     2641 tgaacagaca agccatcagg ccttattggc taaggacaag gaagtacagg ccttggaaaa
     2701 ccagttggcg accttgcgtt tggagcatga aaatcaactg caaaagaccc tttctgacct
     2761 agaaaaagaa cgcaatcagg tcaaaaatca gctcctactg caagaaaagg aaaatgagtt
     2821 gtctttggct tctgttaagc aaaactacga agcccagctc aaagcagcca gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagatttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggcggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aatcactctg ggctattcca cgacgactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattact cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga tgctcttacc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattattag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aaacggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgtatt attcgtcgta tcaagcgtga tatggaggaa
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccataa aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgatcta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc taccccaatt
     6361 ttctaagaga attggggtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttaactcatt tgcaaaatca
     6781 ggaaaaacgg atggcaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttagatagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccattgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aatccttgca ggttaccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 tgaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 ttcgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attaccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gatacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aagctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagct atgaatgaca tggaaagtgt cgaagagtat
    10381 gatcctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctcatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtggggg aaatgaaatg gttgaatttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagtatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acagtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc ttaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcggcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atctttgttc acgcaggtat
    11701 tgatttgacc ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacaggaga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccatgg aaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggagct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccatttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 atacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttatccagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taagaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa tcatgttttg agctgacttc
    14101 gtcagtttca tctacaacct caaaactgtg ttttgagtaa cctgcggcta gcttcctagt
    14161 ttgctctttg attttcattg agtattagaa ca
//
LOCUS       DAVKZI010000049        13566 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKZI010000049 DAVKZI010000000
VERSION     DAVKZI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.050"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            88..3189
                     /locus_tag="VXB18_001817"
     CDS             88..3189
                     /locus_tag="VXB18_001817"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0382979.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASFLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3272..4279
                     /gene="pfkA"
                     /locus_tag="VXB18_001818"
     CDS             3272..4279
                     /gene="pfkA"
                     /locus_tag="VXB18_001818"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0382980.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4338..5843
                     /gene="pyk"
                     /locus_tag="VXB18_001819"
     CDS             4338..5843
                     /gene="pyk"
                     /locus_tag="VXB18_001819"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0382981.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTSEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6164..6412)
                     /locus_tag="VXB18_001820"
     CDS             complement(6164..6412)
                     /locus_tag="VXB18_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0382982.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRLNLDK"
     gene            complement(6578..6803)
                     /locus_tag="VXB18_001821"
                     /pseudo
     CDS             complement(6578..6803)
                     /locus_tag="VXB18_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7651..8523
                     /locus_tag="VXB18_001822"
     CDS             7651..8523
                     /locus_tag="VXB18_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0382983.1"
                     /translation="MKKSRKLATLGICSALFLGLTACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8672..9013)
                     /locus_tag="VXB18_001823"
                     /pseudo
     CDS             complement(8672..9013)
                     /locus_tag="VXB18_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9156..9467
                     /locus_tag="VXB18_001824"
     CDS             9156..9467
                     /locus_tag="VXB18_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0382984.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETAEKILALVPQDLIKQI
                     PFFVRKHATTRTIKRILIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9471..10187
                     /locus_tag="VXB18_001825"
     CDS             9471..10187
                     /locus_tag="VXB18_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0382985.1"
                     /translation="MKKYFIGGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10317..11132)
                     /locus_tag="VXB18_001826"
     CDS             complement(10317..11132)
                     /locus_tag="VXB18_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0382986.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11129..12034)
                     /locus_tag="VXB18_001827"
     CDS             complement(11129..12034)
                     /locus_tag="VXB18_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0382987.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            12376..12732
                     /locus_tag="VXB18_001828"
     CDS             12376..12732
                     /locus_tag="VXB18_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0382988.1"
                     /translation="MLHQGDKNSLLESLSIVERQTLKDIEVIIVNQSTEEIASISQQM
                     NLSFNIKIIDENSFAELSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGH
                     FADLVDGVFYFYPWGG"
     gene            12737..>13566
                     /locus_tag="VXB18_001829"
     CDS             12737..>13566
                     /locus_tag="VXB18_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV0382989.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNFIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     "
BASE COUNT         4312 a         2286 c         2832 g         4136 t
ORIGIN      
        1 agtaagctga tgaaattttt ctcaagagaa gccatttata agtgaaaatg gtataatata
       61 gtgagaagga tagaggagaa gtgtaaattg atcgcacaac tagatacaaa aacagtctat
      121 agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa agaatacggc
      181 tacactcatt tggctatgat ggatattgac aatctttatg gcgctttcga ctttctagag
      241 attacaaaaa aatacggcat tcatcctttg ctagggcttg aaatgacagt gtttgtagat
      301 gatcaggaag tgaatttgcg ctttttagct ctatctagtg tgggctatca gcagttgatg
      361 aagctttcga cagccaagat gcagggggag aaaacttggt cagtcctgtc ccagtacctg
      421 gaggatatcg cggtcattgt gccttatttt gatagagttg agtcgttaga actaggctgt
      481 gattactata taggggttta tccagaaaca ctagcaagcg aatttcatca tcctatctta
      541 cctctttatc gggtcaacgc ttttgaaagc agggatagag aagttcttca agttttaaca
      601 gcgattaaag aaaatctacc gctcagagaa gttcccttgc gttcgagaca agatgtcttt
      661 atatcagcaa gttttttaga gaaactattc caagagcgtt ttccgcaagc tttggacaat
      721 ttagaaaagc ttatttcagg catttcttac gacttggata ctagtctgaa actgcctcgt
      781 tttaatccag ctagaccagc agtagaggag ttgagagagc gtgctgaact ggggcttgtt
      841 cagaaggggt tgactagtaa agaatatcaa gatagactag accaagaatt gtctgttatt
      901 catgatatgg gctttgatga ttatttcttg gttgtttggg atttgttgcg ttttggacga
      961 tcgaatggct attatatggg aatgggaagg ggttctgcag taggcagttt ggtttcttat
     1021 gccttagaca tcacggggat tgacccagta gagaaaaatc tgatttttga acgctttctt
     1081 aatcgtgaac gctataccat gcctgatatt gatattgata tcccagatat ttatcgtcca
     1141 gattttatca gatatgttgg taataaatat ggtagtaaac atgcggcaca aatcgttact
     1201 ttttcaacct ttggagccaa gcaagctctt cgagatgtct tgaaacgctt tggtgtgcca
     1261 gagtatgaat tatctgcaat tactaagaaa atcagttttc gtgacaatct taagtcggcc
     1321 tatgagggca atctccagtt tcgtcagcaa atcaatagta agttagaata ccaaaaagct
     1381 tttgagattg cttgcaagat agagggctat ccaaggcaaa cctctgtcca tgcggctggt
     1441 gttgtaatta gtgaccaaga tttaaccaac tacattcctc taaagtatgg tgatgaaatt
     1501 ccactgactc agtatgatgc tcatggagtt gaggctagcg gacttttgaa gatggacttt
     1561 ctgggactac gaaatttgac ctttgtccag aagatgcaag agttgcttgc tgaaatagaa
     1621 ggtattcacc ttaaaattga agaaatagat ttggaagaca aagaaacgtt agctttattt
     1681 gcctctggaa atacaaaagg tatctttcaa tttgagcaac caggtgccat tcgtctgctt
     1741 aagcgtgtgc aaccagtctg ttttgaagat gtcgtcgcga ctacttctct aaatcgaccg
     1801 ggtgctagtg actatatcaa taattttgtg gcaagaaagc atgggcagga agaagtgact
     1861 gttctggatc cagtactgga ggatattttg gctccaacct acggcataat gctctatcag
     1921 gagcaggtta tgcaggttgc ccagcgattt gccggattta gtcttgggaa agccgatatt
     1981 ttgcgtcggg ctatggggaa aaaggatgcc tctgccatgc atgagatgag ggcttccttt
     2041 attcaaggtt cattagaagc tggtcatact gtggaaaaag cagagcaggt ctttgatgtt
     2101 atggagaagt ttgcaggtta tggttttaac aggtcacacg cctatgccta ctcagccttg
     2161 gccttccagt tggcttattt taaaacacat tatccagcca ttttttatca ggtcatgtta
     2221 aattcttcca acagtgatta cttaatagat gcacttgaag caggttttga agtagcctct
     2281 ctatccatca acacgattcc ctatcacgat aaaattgcca acaaggccat ctatctaggt
     2341 ttgaaatcca ttaaaggagt cagtaatgat ttagctctct ggattattga aaatagacct
     2401 tattctaaca ttgaagattt tatagctaaa ttacctgaga attatctgaa acttcctctg
     2461 ctagaacctt tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg tcaaaaagta
     2521 tttaataatt tagctaatct atttgaattt gtgaaagagt tgggaagttt gtttggagat
     2581 gctatttata gttggcagga atcggaagat tggacggaac aagaaaaatt ttatatggaa
     2641 caagagcttt tagggatagg tgtcagcaaa catccactac aagctattgc aagtaaggct
     2701 atttacccga ttaccccaat cggaaatttg tcagaaaata gctatgctat tatcttggtt
     2761 gaagttcaga aaataaaagt gattcgtacc aaaaagggtg aaaatatggc cttcttacag
     2821 gcagatgata gtaagaaaaa attggatgtc actctctttt cagacttata tcgtcaggtt
     2881 ggacaggaaa taaaagaggg agccttctac tatgtaaaag gaaaaataca atcacgtgat
     2941 ggccgtctgc aaatgattgc acaagaaata agagaagcag ttgctgaacg cttttggata
     3001 caggtgaaaa atcatgaatc ggatcaagaa atttcacgca ttttagaaca atttaaaggc
     3061 ccaatcccag tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc tccccatcat
     3121 tttgtagcta aatccaatga attagaggag aaattgaatg aaatcgttat gaaaacgatt
     3181 tatcgctaaa aatacggaaa atagaagaat tttaaaatca aatgtgatat aatcaagaag
     3241 aatgttaaaa gaaaaaggag cataaaccaa tatgaaacgt attgctgttt tgactagtgg
     3301 cggagacgca cctggtatga acgctgccat ccgtgcagtt gttcgtcaag caatttcaga
     3361 aggaatggaa gtgtttggta tctatgacgg atatgctggt atggttgctg gtgaaattca
     3421 tcccctggat gcagcttcag taggggacat catttctcgt ggtggtactt ttcttcactc
     3481 agctcgttat ccagagttcg ctcaacttga agggcaactt aaagggattg agcaattgaa
     3541 aaaacacgga attgaaggtg tagttgttat cggtggtgac ggatcttacc acggcgctat
     3601 gcgtttgact gaacatggct tcccagctat tggtcttcca ggtacaatcg ataacgatat
     3661 cgttggtact gactttacaa tcggttttga cacagcggtt actactgcca tggacgctat
     3721 cgataagatt cgtgatacat catcaagtca ccgtcgtact tttgtaatcg aagttatggg
     3781 acgtaacgct ggtgatatcg ctctttgggc tggtattgca actggtgctg atgaaatcat
     3841 catccctgaa gcaggcttca agatggaaga tatcgtagca agcatcaaag ctggttatga
     3901 atgtggtaaa aaacacaata tcatcgtctt agctgaaggt gtgatgtcag cggctgaatt
     3961 tggtcaaaaa cttaaagaag ctggagatac aagcgacctt cgtgtaacag aacttggaca
     4021 tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt ttggcgtcac gtatgggtgc
     4081 acatgctgtt aaacttctta aagaaggtat cggtggtgtt gcggttggta ttcgtaacga
     4141 aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa ggggcattgt ttagccttac
     4201 tgcagaaggt aagattgtgg ttaacaaccc gcacaaagcc gatattgagc tatctagctt
     4261 gaataagagc ttgtcataat ttacaattta gttaataaga ccaaaaaggt catatatata
     4321 aaggagtcac aaaaatcatg aacaaacgtg taaagatcgt tgcaactttg ggtcctgcgg
     4381 tagaaatccg tggtggtaaa aaattcggtg aggatggata ctggggtgaa aaacttgatg
     4441 ttgaagcttc agctaaaaac attgctaaat tgattgaagc tggtgctaac acattccgat
     4501 tcaacttctc acacggcgac caccaagaac aaggtgagcg tatggcaact gttaaacttg
     4561 cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga tacaaaagga cctgaaatcc
     4621 gtacagaatt gttcgaaggt gaagctaaag aatattcata caaaactagt gaaaaaattc
     4681 gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt gattgcgttg aacgttgctg
     4741 gtgctcttga tatctatgat gatgttgaag ttggtcgtca agttttggtt gacgatggta
     4801 aacttggtct tcgtgtggtt gctaaagatg atgcaactcg tgaatttgaa gttgaagttg
     4861 aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat ccctaacact aaaattcctt
     4921 tcccagctct tgctgaacgc gataacgacg atatccgttt cggtcttgaa caaggtatca
     4981 acttcatcgc aatttcattc gtacgtactg caaaagatgt gaacgaagtt cgtgcaatct
     5041 gtgaagaaac tggaaacgga catgttcaat tgttcgctaa aatcgaaaac caacaaggta
     5101 tcgataactt agacgaaatc atcgaagcag ctgatggtat tatgattgct cgtggtgata
     5161 tgggtatcga agtaccgttc gaaatggttc cagtttatca aaaaatgatt atcaagaaag
     5221 tcaatgctgc aggtaaagtt gttatcactg caacaaacat gcttgaaaca atgactgaaa
     5281 aaccacgtgc aactcgttca gaagtatcag acgtattcaa cgctgttatc gacggaactg
     5341 acgctacaat gctgtcaggc gagtctgcaa acggtaaata cccactcgag tcagtaacta
     5401 caatggctac aatcgacaag aacgctcaag ctcttcttaa tgaatacgga cgtcttgatt
     5461 cagattcatt tgagcgtaac tctaagacag aagtaatggc ttctgctgtt aaagatgcta
     5521 ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa gacaggtcat actgcacgtt
     5581 tgatttctaa ataccgtcca aatgctgaca tcttagcatt gacatttgac gaattgacag
     5641 aacgtggctt gatgttgaac tggggtgtta tcccaatgtt gacagatgct ccatcttcaa
     5701 ctgacgatat gttcgaaatc gctgaacgta aagcggtaga agcaggtctc gttgagtcag
     5761 gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga agctgttcgc acaaacacaa
     5821 tgcgtatccg cacagtacgt taagaaaaat ataaaaacct atcatatcca gctttctagc
     5881 ctgtatgatg ggctcttttt ttgtccaggg ggcaaaaagg gggcaaaact ttcataatgg
     5941 attgatactc ttcgaaaatc aaattcaaac cacgtcagcg tcgccttacc gtatatatgt
     6001 tactgacttc gtcagttcta tctacaacct caaagcagtg ctttgagcaa cctgcggcta
     6061 gcttcctagt ttgctctttg attttcattg agtatgaaat aagatatgca caaattgatt
     6121 agaaagtcaa atgaatttct acaaatgttt tagcaatcgc aatctacttg tctagattca
     6181 atctgatata ttttcgattt aatgatatgg tatttaaaac ctccaaagta gcttgctcca
     6241 ttcttttact tacgtgagtg tagatgttat ttactgtttt agcgtttttg tgttccactc
     6301 taaccattat agcattcttc tcagctagtg tactaaggag tgtgtgcctg aaaatatggg
     6361 aactaagggg ctggtttatc ggtttctcta gtttagtatt tgccttttgc aaagtgatct
     6421 taaatgcctt tctctaaatt tacatatcac tattgtttaa caaaatctaa tctactttag
     6481 gtcacttatt ctttttttga aatgtagaat gaactttttc aaagtttttc gaatctttta
     6541 aaatctgttt gttttatatc gccattctcc ccctttttta attctcccta tatagcctga
     6601 tagctttccc gatggtacga atatggttgc tttcgtctag gtggatgtcg gggtattcgg
     6661 gattgagttt ttttgaggca gccttggcgg agtttcttga catagttagt gccgtctact
     6721 tggaagatgc cgatggtatt atagtcaatc tgtggggtat tcttgataaa taggtagtcg
     6781 ctgtttctta tctttggctt catggacttg ctgacgacat aagcgattgg gtcgtagtcg
     6841 tctgggataa tggaaactcc ataactaaat cgtcgtcctg catcgagcgg ctacctgcag
     6901 agataaacta cctaacacga gagtaagtag tctgtctgta gtcgtccagt ctgatgattt
     6961 ttacgatact tcgtttttct gatcatacag ttgcctctcg gcataggtca gaactttacc
     7021 ttgtctgggt ggtgcccgtt ggtcgtagat agattggata tcgctaggag aatccttttg
     7081 aactggagga aagagggcat caatcaagct actgaatact ttaactaagt caaatatagt
     7141 atttttctta gtagacctaa cccttttttc ataatttcta atggtgtttt tacttatacc
     7201 tatcttagta cccaattctt attgagtcca accattacta gtctatattg ttttatagtt
     7261 gattgagttt ggaatagtac gctgtagctg ctaaaacatt tctaggaatt aatttgcctt
     7321 tcctaataga gttgttcata tcttatttca atctactata tttttcacct ctaacaatcg
     7381 caatctcttc tttatccatg aataaaaacg atttctattt ttgtaagtaa agcatcacac
     7441 gaaatccacg aaaatgaaaa cctttgttgt gttttcgtaa aaaatttgtt gacagagcac
     7501 gaaacgccta ctataattaa atcaagttta aggaaataac aaaaaaacaa atcggaggga
     7561 aagacgatga acacattaaa tgagaaagta atcaatatct gtaaagcagt agttaaagaa
     7621 actttaatcc aagacattta ggagaaagaa atgaagaaat caagaaaatt agccacatta
     7681 ggaatctgtt cagctttgtt tttaggcttg actgcttgtc aacaacaaca tgctacttct
     7741 gaggggacga atcaaaggca aagcagttca gcgaaagttc catggaaagc ttcatacacc
     7801 aacctaaaca accaggtaag tacagaagag gtcaaatctc tcttatcagc tcacttggat
     7861 ccaaatagtg ttgatgcatt ttttaatctc gttaatgact ataataccat tgtcggctca
     7921 actggcttat caggagattt cacttccttt actcacaccg aatacgatgt tgagaaaatc
     7981 agtcatctct ggaatcaaaa gaagggcgat ttcgttggga ccaactgccg tatcaatagt
     8041 tattgtcttt tgaaaaattc agtcaccatt ccaaagcttg aaaagaatga ccagttgctt
     8101 ttcctagata atgatgcgat tgataaagga aaggtctttg attcacaaga taaggaagag
     8161 tttgatattc tattttcgag agttccaact gaggcaacta cagatgtcaa ggttcacgct
     8221 gaaaagatgg aaacattctt ctcacaattt caattcaatg aaaaagctcg aatgctgtct
     8281 gtagtcttgc acgacaatct ggatggcgag tatctgtttg taggccacgt tggggtctta
     8341 gtacctgctg atgacggttt cttatttgta gagaaattga ctttcgaaga gccctaccaa
     8401 gcgattaaat ttgctagtaa ggaagattgc tacaagtatt tgggcaccaa gtatgcggat
     8461 tatacaggcg agggactggc taagcctttt atcatggata atgataagtg ggttaaactt
     8521 taatagtgtt atgatatgac agtaatctta ggatttttat ttctattttt gatgagttgg
     8581 tgggttattt caatcgttaa tagccagaaa ccacgcaaaa atgaaacatt tattggctat
     8641 gtccaaagat acgatattga tgggaatggc tatcaatcat taccgtgtcc tcagagctga
     8701 gaggagttct tgaaatcgta acaccacttt gaacaagagt tacttcaacc cattggctcc
     8761 gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttgttca taagtgcggt
     8821 attctcgcac atattgaaga gtggctataa gaaggtcttc taggcttaat ttaggttttc
     8881 gtccaccttt tgcatgttta agttgataag ctgtttttaa tacagctaac atctcttcaa
     8941 aagtcgtgcg ctgaacacca acaagacatt tcaatcgtgc atcagttagt tgtttacttg
     9001 cttcatcatt catagaacta ttataccatg ttttgtttcg caggaaatct aatgctaaaa
     9061 tcttatcagt gagaagattt cttaaagttt attctttgta gtttcatctg tattagtaca
     9121 taatttaacc tagagaaaat aggaggacta atcgaatgga attaaaagat tttacagaaa
     9181 aagaacagga aatgattaag aaaaggctta caatgtctaa tattagtgac aaagaaactg
     9241 ctgagaagat tctggcgcta gtaccacaag acttgattaa gcaaatcccg ttttttgtca
     9301 gaaaacatgc tacaacacgt acgattaaac gcattttaat tgaataccct gaactctacg
     9361 ctgtagctca aacaagtggt gagattccag aaaaagaacg cgaagaattg cgtcagatta
     9421 tcacaactat ctttgaacaa aagatgaata agcatagtat taagtagaga atgaaaaaat
     9481 attttattgg cggtttggga agcaatgcct atcatagcaa ggattttttt caagaactag
     9541 attcgcaggt ctattttcta aatccatatg aaaagcatct tcgagatgaa acagaattga
     9601 aatcatggtt taaaaatgag attgtagagg aagaatctat ctgtctgata ggccattctc
     9661 ttggaggaga tttagctcgt tatttcgcat cggaatttga agaagtaaag aaactgattc
     9721 ttttggatgg tggctatcta gatttagata agattttacc tttggataca gagttagagg
     9781 aaactaaaaa ttatatcaaa tctcaaattg tttcggactt agctcttctt atttctaaag
     9841 agaagtccga agcaaagcat tggtcagaaa atatggagaa agctgtaaga cagtcctatc
     9901 actggaatgt tgagtataat agatatgagt tggctataaa ttatgaaaat atagaagcga
     9961 tactccgcct acggagaaaa atacaagctt ttaagagaga agtgggagat accttgttta
    10021 ttagtcctcg ctatcctaat ggagctacat ggagagagga agccctaaaa gaattgccag
    10081 actattttaa tactattttt ttagaaaact ttggccatga gctttatact caagcaccta
    10141 aagaaatcgc tagtctaatg aatgagtggc tcgcttattt tctatgagct acttgtattg
    10201 ctggaaatgg tataagatga aaatctacaa gtcactaatt ttcatataac aaaaaaacga
    10261 acaggctctt tttctgttat tcagaagaga acttgttcgt ttttatcttg attttcttaa
    10321 aaagctctat atacataggg attttctggt ttatcgactt tggtaaagct gtcgatttcc
    10381 aaggttggaa ggttttgttt gagttcttta tggtagtgat tgaccagttt tcctttggct
    10441 gtaatccagg tgttgttttc atactgccgg gtattgccct tggtcagcaa tccatagaca
    10501 ccagaatctg cgatacagtg gataatgccg aatcggaaca gaaattgact attggcatga
    10561 ctggggtcgt tatagacaaa gcctgtaaac tggattgtct tgccctcaaa ttcatctgga
    10621 tagtcgtaga tagcctccat gacttccata tagttttcat tagtgatctg aatactatct
    10681 tgggataagt atttatccgc cgccgttcgc atttcctttt cataggctga ttttgaaaaa
    10741 taagaactag tatctggttt caaatattgg cttgtagtcc cttcacttgt ctgaatagct
    10801 agatccgttc cttccgatag ggggaaatga taacctttag cagaaacggt ctgagaatcc
    10861 aagctaacag ttgggaaagt taagccgatg acaagtggaa tagccagaag agaaatactc
    10921 gtcatcttgg ccaatcggct gttcagatga ctgtgggttt tgacttgctt catccagata
    10981 tacaattgaa caattgccaa gataaaggaa agcaccatgg agatataggc cagataggaa
    11041 tagtgcatgt tgatgtactg gtttagtttg cccgacagat ggaggtaaat agtcagttca
    11101 aaatagccag ctaaaactaa aaatcgaatc ataggatgac tccaatcaag agagaatagg
    11161 ctaaaacgac cagagtcaca atcgtaatga agtgactaat aaatcgtgct ttcaagtaat
    11221 ttttcatcat gagaatattt ttgatatcca gcattgggcc aatgacgaga aaggccagaa
    11281 ctggtgccaa accgaaactc gagagtagag aagcacctat aaaggcatcc gcctcactac
    11341 agagcgaaag aagaaaggct aaaagcatca agagcaggat agcaaaaaga ggagtcgcac
    11401 tgatagaggt cagaatccga gtcggaacgt agacctgtat tatagaagca aagaggcagc
    11461 caaataccaa ataacgcccc gtatcaaaaa attcatcaat ggcctgcaca aagacttgaa
    11521 aaactttttt tgcagaactc aagtaagaaa aatcatgctc atgacaagcc agacgatttt
    11581 ctttctgaat cggttcttgc cagaaaaatc ctagaaaaat tcctagtatt acagccacaa
    11641 gaatggaacc cagagctcgt aatagggcga catggaagga gttgccaaag gcagaatagg
    11701 tcgcaaaaag aacaatggga ttgataacag gtgctgtcac aagaaaagga acggccgtgt
    11761 aacttggaac ctttttttcc agaaaacgat tgatgatggg gacgattcca cattcacagg
    11821 aagggaaaag tataccgaca aaggtcccaa aaaagattct cccccaacga tttcgaggga
    11881 gaaaatgata aaccttgtca ggtgtgatat aaacttcaat cagccctgag acaatgcttc
    11941 ctatcagaac gaagggaagg gcttcaatga taatggagag aaaaatggct ccagtttgaa
    12001 gtacactaga tgggagttgt tgaaaagcag tcatctagtt tttcttttct gctttggctt
    12061 ttttctcttt gtcatcaggg aaagtgactt gtttcaaatc agggagttta gcaaactctt
    12121 caaacatctt gtccaagtcg tctcgttttg taaatttgac agccataggt gtacctcgat
    12181 tctaaattct acctctatta tactattatt ttgcggaaaa gggaaaagtt aaaatttcaa
    12241 attgagtagc taagagataa tatagcttga tattacctga tatatatcat aattgtgcta
    12301 taattaaata aaaagaaaat cattatcaga aaattatggg aggtagtcaa actgacttac
    12361 tcaattagtg ttgttttgtt acatcaagga gataaaaata gtttattaga gtctttgtca
    12421 atagtggaga gacaaacatt aaaagatata gaagttatta ttgtaaatca atctacagag
    12481 gagatagctt ccattagcca acagatgaat ctatcattta atattaagat tatagatgag
    12541 aattcttttg ctgagttgtc tgatatgatt acaggagatt atattacgtt tctatcttca
    12601 aatgattcat tatttgattg gacatttgaa aagatgtatc atgcgataaa attatccgat
    12661 tctgatgttg ttcttggtca ttttgctgat ttggttgatg gagtatttta cttttatcct
    12721 tgggggggat aattggttga cagaaaattt aacgaatgtt caagttttac aaaagatgga
    12781 tgatacagat catcgaatta gaaaacaata tcgctcatta tttggaaaat tattcaatag
    12841 taagctttta cgaaaaataa atcaatttga tataaacaac tttatttgga gactttatat
    12901 tcactctaaa actgcaacct atattaattt cccgacatat atctataaac ctgttataga
    12961 tgctaaacct ctaaaagact cctacaaaat catattagaa aattatgaaa atagaatcaa
    13021 agattgcgcc gtcttagaaa actatgatat agaaagagcg aaaaaacaat atattcaaga
    13081 attggcaaat tttagtgctt ggttaaaaaa tgacggtgaa tatttagatt ctgatattgt
    13141 ttatcataag ttaatagctg cagagaaagg aattttccct tttcttgagc ttgatagatt
    13201 agattttacg attataagta ataattgtgt tggaggatta atttataaac agcttggttt
    13261 tcaatataga acaccttttg ttggtttatt tattcttcct gatgattatt ataaacttac
    13321 aaagcatttt cgttattata tggaacaaga acttgttttc gaagaggaac ttatttcacc
    13381 gagctggact catgaagttt atcctttggg gcacttagga gatatagata ttcattttct
    13441 acattattct agtattgaag aagcacgaac taagtgggaa aaaagaaaaa aacgcataaa
    13501 ttggaataat ctttatttta aatttgataa taaagattca gctagtgaag aaattttaaa
    13561 taagat
//
LOCUS       DAVKZI010000050        13477 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKZI010000050 DAVKZI010000000
VERSION     DAVKZI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.051"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..565
                     /locus_tag="VXB18_001830"
                     /pseudo
     CDS             1..565
                     /locus_tag="VXB18_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            756..3047
                     /gene="pcrA"
                     /locus_tag="VXB18_001831"
     CDS             756..3047
                     /gene="pcrA"
                     /locus_tag="VXB18_001831"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0382990.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            3090..3770
                     /gene="radC"
                     /locus_tag="VXB18_001832"
     CDS             3090..3770
                     /gene="radC"
                     /locus_tag="VXB18_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0382991.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3767..4456)
                     /locus_tag="VXB18_001833"
     CDS             complement(3767..4456)
                     /locus_tag="VXB18_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0382992.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDTGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4474..5115)
                     /locus_tag="VXB18_001834"
     CDS             complement(4474..5115)
                     /locus_tag="VXB18_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0382993.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5198..5413)
                     /locus_tag="VXB18_001835"
     CDS             complement(5198..5413)
                     /locus_tag="VXB18_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0382994.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5421..5768)
                     /locus_tag="VXB18_001836"
     CDS             complement(5421..5768)
                     /locus_tag="VXB18_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0382995.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5773..6888)
                     /locus_tag="VXB18_001837"
     CDS             complement(5773..6888)
                     /locus_tag="VXB18_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0382996.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6898..7857)
                     /locus_tag="VXB18_001838"
     CDS             complement(6898..7857)
                     /locus_tag="VXB18_001838"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0382997.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7970..8539)
                     /locus_tag="VXB18_001839"
     CDS             complement(7970..8539)
                     /locus_tag="VXB18_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0382998.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8667..9338
                     /locus_tag="VXB18_001840"
     CDS             8667..9338
                     /locus_tag="VXB18_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0382999.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9322..10140
                     /locus_tag="VXB18_001841"
     CDS             9322..10140
                     /locus_tag="VXB18_001841"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0383000.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRNRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10137..11033
                     /locus_tag="VXB18_001842"
     CDS             10137..11033
                     /locus_tag="VXB18_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0383001.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFNHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            11077..12051
                     /gene="pta"
                     /locus_tag="VXB18_001843"
     CDS             11077..12051
                     /gene="pta"
                     /locus_tag="VXB18_001843"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0383002.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(12313..13477)
                     /locus_tag="VXB18_001844"
                     /pseudo
     CDS             complement(12313..13477)
                     /locus_tag="VXB18_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3968 a         2544 c         2902 g         4063 t
ORIGIN      
        1 aacttaatcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg tgttacgatt
       61 tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtaaaaatc
      121 aatcgcccta aaaaaagaat tagcgaatga ttctggtaaa aagaaatttc acgctatgaa
      181 ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatcg ctgtgaacta
      241 ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat
      301 cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg
      361 taaatccagc aaactcaagc cgctaacagt tgaagataaa gcttataacc atgcgctatc
      421 caaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta aaatgttttc
      481 aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggtat
      541 tatcaatcat gaactaggat tctagttttg caggaagtct attgaggtat tgagctagtt
      601 tatgaaaaaa ttgggtgaaa agtcgagtgt tttagaaacc cacagtgtag tattctagtt
      661 tcaatccact atattttgct actccccgta aagtttctat tttccctgat ttctgatata
      721 atagaaatat tgacttcaag agtaaggaag agaagatgaa cgcattatta aatggaatga
      781 atgaccgtca ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc atggcagggg
      841 ctggttctgg aaagactcgt gttttaaccc accgtatcgc ttatttgatt gatgaaaagc
      901 tggtcaatcc ttggaatatc ttggccatta cctttaccaa caaggctgcg cgtgagatga
      961 aagagcgtgc ttatagcctc aatccagcta ctcaggactg tctgattgcg accttccact
     1021 ccatgtgtgt gcgtattttg cgtcgcgatg cggaccatat tggctacaat cgtaatttta
     1081 caattgtgga tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa cagttgaact
     1141 tggatcctaa aaaatggaat gaacgaacta ttttggggac catttccaat gctaagaatg
     1201 atttgattga tgatgttgct tatgctgccc aagctggcga tatgtatacg caaattgtgg
     1261 cccagtgtta tacagcctat caaaaagaac ttcgtcagtc tgaatccgtt gactttgatg
     1321 atttgattat gctgaccttg cgtctctttg atcaaaatcc tgatgttttg acctactacc
     1381 agcaaaaatt ccaatacatc cacgttgatg agtaccaaga taccaaccat gctcagtacc
     1441 aattggtcaa actcttggct tcccgtttta aaaatatctg tgtggttggg gatgcggacc
     1501 agtctatcta cggttggcgt ggtgctgata tgcagaatat cttggacttt gaaaaggatt
     1561 accccaaagc caaggttgtt ttgttggagg aaaattaccg ctcaaccaaa accattctcc
     1621 aagcggccaa cgaggttatt aaaaataata aaaatcgccg tcctaaaaat ctctggactc
     1681 aaaacgctga tggggagcaa atcgtttact atcgtgccga tgatgagctg gatgaggctg
     1741 tatttgtagc cagaaccatc gatgaactta gtcgcagtca aaacttcctt cataaggatt
     1801 ttgcagttct ctatcggact aatgcccagt cccgtacaat tgaggaagcc ctgctcaagt
     1861 ctaacattcc ttataccatg gttggcggaa ccaaattcta cagccgtaag gaaattcgcg
     1921 atattattgc ttatctcaac cttattgcta atttgagtga caatattagt tttgagcgta
     1981 ttatcaacga gcctaaacgt ggaattggtc taggtacagt tgagaaaatc cgtgattttg
     2041 caaatttgca aaatatgtct atgctggatg cttctgctaa tattatgttg tctggtatca
     2101 agggtaaggc agcccaatct atctgggatt ttgccaatat gatgcttgat ttgcgggagc
     2161 agctagacca cttaagcatt acagagttgg ttgagtccgt cctagaaaaa acaggttatg
     2221 tcgatattct taacgcccaa gcgactctag aaagcaaggc acgggttgaa aatatcgaag
     2281 agtttctttc tgttacgaag aactttgatg acaccactga tgtgacagaa gaggaaactg
     2341 gtctggacaa actgagtcgt ttcttaaatg acttggcttt gattgccgac acagattcag
     2401 gtagtcagga gacatcagaa gtgaccttga tgaccctgca tgctgccaaa ggtctcgaat
     2461 ttccagttgt ctttttgatt gggatggaag aaaatgtctt tccacttagt cgtgcgactg
     2521 aagatccaga tgaattagaa gaagagcgcc gtctagccta tgtaggtatc acgcgtgcag
     2581 agaaaattct ctatctgacc aatgccaact cacgcttgct ttttggtcgt accaattata
     2641 accgtccgac tcgttttatt aacgaaatca gttcagactt gcttgagtat caaggtctgg
     2701 ctcgtcctgc aaatacaagc tttaaggcat catatagcag tggtagtatt tcctttggtc
     2761 aaggtatgag tttggctcag gctcttcaag accgtaaacg cggtgctgcc ccaaaatcaa
     2821 tccagtcaag cggtcttcca tttggtcaat ttacagctgg cgcaaaatca gcatctagcg
     2881 aggcaaattg gtccattggt gacattgctc tccacaagaa atggggagag ggaactgttc
     2941 tggaagtttc aggtagcggt gctaggcagg aattgaaaat caatttccca gaagtaggtt
     3001 tgaaaaaact tttagccagt gtggctccaa ttgagaaaaa aatctaattt tccatccttc
     3061 tcacgaataa taaagtgagg aggattttta tgtacagtat ttcattccaa gaagattcac
     3121 tattaccaag agaaaggctg gccaaggaag gagttgaagc gcttagtaac caagagttgc
     3181 tagctatttt actcaggaca ggaacacgtc aagctagcgt ttttgaaatt gcccaaaaag
     3241 tcttgaacaa tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag gaattgcaga
     3301 gtttgtctgg tattgggcgt gttaaggcca tagaattaca agctatgatt gaactggggc
     3361 atcgtattca caaacacgag actcttgaaa tggaaagtat tctcagcagt caaaagttgg
     3421 ccaagaagat gcagcaggaa ttaggggata aaaaacaaga gcacctggtg gcactctatc
     3481 tcaatactca aaatcaaatc atccatcagc agaccatttt tatcgggtct gtaactcgta
     3541 gtatcgctga accgcgagag attctgcact atgcaatcaa gcatatggcg acttctctta
     3601 tcttggtcca caatcatcct tcaggagcgg tagcgcctag ccaaaatgat gatcatgtca
     3661 ctaaacttgt taaagaagcc tgcgaactga tggggattgt tctcttggac catttgattg
     3721 tctctcattc taattacttt agttatcgtg aaaagacaga tttaatctaa agttcattaa
     3781 cgacatagtc aaagagtttc ttatctttgg gacgattttc aaaaagaagt tctggatgcc
     3841 attggacacc gagaaaggcg acatcatccg tactcatgac agcctcaatg ataccatctt
     3901 taggatcatg agccacaact tttaaatttg gtgctaagtc cttgatgctc tggtggtgga
     3961 aggagttgat atgagagatt tctccataga tttcttggag aacggtatct ggttctgtta
     4021 ccaagcgttg agttgtgtac tcaacagaag aatcctgcca atggtcttcg atatcttggt
     4081 acaaagttcc acccatggca acgttaaaga gttgggtacc acggcagaca gagaaaatgg
     4141 gctttttctg tttaatagct tccttgatga gggccagttc gaagatatct ctttgaaggt
     4201 gatagtcatc gctatcaatg gttttgggtt cgccatagaa ttttggatcg acattttgcc
     4261 cacctgtcaa gatgagcttg tcaatcaaac tgatatagtg gcaggccatt tcttgatcac
     4321 caatcggtag gatgatggga atccctccag tatctttaac gccttcaaca aagccttttg
     4381 ctgcgtagct catcatgatg tcatcatctg gatgagcttt ttcgtttcct gtaatcccaa
     4441 taactggttt tttcataaaa tgattttcgc tttctaatcc tcttttcgca tgaagtagag
     4501 gagggtttgg agttcacttg tcaaatcgac atactgaacg accacgtctt ttggtaaatg
     4561 cagatggact ggtgaaaaac tgagaattcc tttcacacca gcatcaacca agagattagc
     4621 aacctcttgt gacttgacgc tgggaacagt taggatagca gtcttcacat cagcatcctt
     4681 gattttatcc ttgatctgag aaatcccgta aatgggaatc ccgtcaggag tttgggtacc
     4741 gacttcagga tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt tacgttcgtg
     4801 gaagcggtag tggagaaggg catggcccat atttccaata ccaaccagca tgacattggt
     4861 aatagagttg tcattgagca aatcggcaaa aaatgtcatt agttttttga catcatagcc
     4921 aaaaccacga cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg tcgctgaatc
     4981 aataccgata gcctctgcaa tttgcttaga gttggcacgt tcaatctttt ctgcatgaaa
     5041 tctcttaaaa attcgatagt agagagagag tctttttgct gtagcttttg gaatagcaaa
     5101 ctgtttatct ttcacaaaat cacaaccttt ctattcttct attttataga aacattgtga
     5161 aaaaatcaac aaaaataaga aaaaactaag aaaaatctta gttttgatgt aaaaaatctg
     5221 catgagatag aaaacggtag aggtctccga ccagcccctg ataaactttt ttgcccctaa
     5281 aagtcagaga agtcacataa agtgtatctg gtaaggttac acatcctgac aaagtcaaca
     5341 tgagagcctc atgatcctca tacttgagag tacgctctac atgatagcag tccttatagg
     5401 tcagttcaaa cattttggct ctatctttcc gattttgtaa agacaccacg ttctaccaag
     5461 ctatccatga ggaagtagaa tttttcctga tgaatatggt ggtcttctga tttgaaaata
     5521 tcaactagac gaaggccaaa cttgtcagtg atattgattt tagcccctgt aagttccttg
     5581 ttaatgatga ttttgagttg gaagccttca ccgctgtttg gcactttttc caaaaggcga
     5641 gtcagttcat agttaccaac cttagtttca aaaaaggtgt tatctttgag ggtgaatttt
     5701 ttaacagaag ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat gattttttca
     5761 aatgccatat ggctaacctc cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc
     5821 ttcaacggta ttttgtggcg acaaactgat gcgaagggat tccttcaagc gttctgaatt
     5881 tgcgccatac atggctttaa gaacatggct ggattggaca acgcctgcag tacaggctga
     5941 gccagtagag attgaaattc cagctaaatc tagccgaagg agtaagaggt catttttctg
     6001 accaggaaat ccaatattga gaacataagg gagatgatgt tttcctctat tcaagtaata
     6061 ctgaatgccc tccagttctg ccagaaaggc agtttctaga ttttgtacat gttgaaaatg
     6121 ttcttcttgt ttttctaggt cttcttttag ggctgcaacc atgcctacga tggcaggcag
     6181 attttcagtt cctgcacgtt ttttctgttc ctgatctccg ccatgtagat aggaatcaaa
     6241 gtccatgcta gatgcgtaga gaaaaccgat tcccttagga ccatggaatt tgtgggcaga
     6301 agcagtgaga aaatcaatgc ccaattcttc tgaatgaatt gggattttac caatagcctg
     6361 aactgcatca acatgatagg cagcagggtg ttgcttgagt atttggccaa tttcagcgat
     6421 gggaagtagg tttcctgtct cattattggc aaacatagta gaaaccaaaa tcgtatcgtc
     6481 acgtaaagcc ttttgaattt gctgggctgt gatttcttga ttttctggct ggataatggt
     6541 tgcttcaaac ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag catggtgctc
     6601 gatggcagtt gtgatgatat gttttccttg ttcttggtga cgaagacagt agccaatgat
     6661 ggtagtatta ttgccttcag tcccaccaga agtgaaaaag atatgttgag gttttgtcct
     6721 tagtaactgg gctagttcct gacgggcttc tcgcaagagt ttgccagctt gacgaccatg
     6781 accatgaata ctagaaggat ttccgtgggt ttcttgcata accttggtca tagctgaaat
     6841 agcaactgct gacataggag tcgttgcagc attgtccaaa taaatcaaag aatcacctta
     6901 tttcttttta ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa tacggacgat
     6961 agcatcacca attaactcac tagcagtgat gtagcataca tttttaggag ttttttcttt
     7021 tgttgctact gaatcagtca caagaatttc tttaatatta gtattgtcaa gaagctcagc
     7081 agctccctcg acgaagagac cgtggctaga aacagcataa atttctgtag ctccttcacg
     7141 ttcaacgatt ttagaagctt cagagaaggt acgtcctgta tttaaaatat catcaatcaa
     7201 gatagctttc ttaccttcaa catcaccaat aatataacct tcgttacgag ttgcatcgtc
     7261 ttgagggtag tcgataatgg cgataggagc atcaagatat tcagccaggc tacgcgcacg
     7321 tttgacacct gaatttttag ggctaacgac aacaacatct gaaccaagca atcctttatc
     7381 gcagtaatgt tttgcgaata ggggaacagt gaaaagatta tccactggaa tatcaaagaa
     7441 accttgaacc tgaacggcat gcaaatcaag agtcaggata cgatcaactc cagccttaac
     7501 cagcatattg gcaactagtt ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg
     7561 acgtgcatag ccaaaatatg gaaggacaac gttgatactg tgggcacttg cacgcacaca
     7621 agcatcgacc atgattaaca attccattag gtggttgttg acagggaaac ttgttgattg
     7681 gatgatgtaa acatcataac cacggacact ttcttcgata tttacttgga tttctccgtc
     7741 tgaaaattga cgtgatgata gttttccaag tgggacacca acagcttggg caattttttg
     7801 tgcaatctct tggttagagt tgagtgcgaa aagtttcatg ttttttctat ctgacattat
     7861 agaccgtcct ctgtaaactt tataaatcct agttatattt accttacata tatgaactgg
     7921 gatttgtgta tttttatctt ttctatttta ccaaaaaatg gagattattt cagctatttt
     7981 tcatactttt gacaaatcga accaattttg aaggagcttt ttggtaggaa atctgatttt
     8041 tctctaaaaa ttgtcggaaa tcctgtttgc cttgctcatg attttccact tcaagctcca
     8101 attcgtaatc tgttatatca aagtatcggc tctgatccag tgccatgaga ccaatagctg
     8161 ttttcatttc atagcgaagc gttgttagac aaccaagaac ctgccagttc ttactttgga
     8221 taccatgttt cgccaattca tccagtacta gcccttgagg aagttcttcc ttactcagat
     8281 agttctcagc atcttttagt tgcaattttt ggttgtattc catgtttcca acactctgcg
     8341 ggactttgag tgtcaactca gcccagtctt caaaggttcg aatgcgcata gcgactttct
     8401 tttctcgcag ttcaaaatca ggcgtgtcga tgtagtaatt tgtttgaaga acaggagtga
     8461 cacctgtgaa ctggtctttt agacgattgt attcatcttt tttcaatagt gttttcaatt
     8521 caatttctaa atgtttcatt tttcttacct ttttttatcg ttgaaagcgg atttatggta
     8581 taataagcat tgtatttatt gtatatgaat ctggagaaaa aatcaaagat atttttgacg
     8641 gataatatga gaacaaggga gaatatatga ccttagaatg ggaagaattt ctagatcctt
     8701 acattcaagc tgttggtgag ttaaagatta aacttcgtgg tattcgtaag caatatcgta
     8761 agcaaaataa gcattctcca attgagtttg tgaccggtcg agtcaagcca attgagagca
     8821 tcaaagaaaa aatggctcgt cgtggcatta cttatgcgac cttggaacac gatttgcagg
     8881 atattgctgg cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa gtagtggata
     8941 ttttgcacaa gcgtcaggat atgcgaatca tacaggagcg agattacatt actcatagaa
     9001 aagcatcagg ctatcgttcc tatcatgtgg tagtagaata tacggttgat accatcaatg
     9061 gagctaagac tattttggca gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa
     9121 cgatagaaca ttctctcaac tacaagtacc aaggggattt cccagatgag attaagaagc
     9181 gactggaaat tacagctaga atcgcccatc agttggatga agaaatgggt gaaattcgtg
     9241 atgatatcca agaagcccag gcactttttg atcctttgag tagaaaatta aatgacggtg
     9301 taggaaacag tgacgataca gatgaagaat acaggtaaac gaattgatct gatagccaat
     9361 agaaaaccgc agagtcaaag ggttttgtat gaattgcgaa atcgtttgaa gagaaatcag
     9421 tttatactca atgataccaa tccggatatt gtcatttcca ttggcgggga tggtatgctc
     9481 ttgtcggcct ttcataagta cgaaaatcag cttgacaagg tccgctttat cggtcttcat
     9541 actggacatt tgggcttcta tacagattat cgtgattttg agttggacaa gctagtgact
     9601 aatttgcagc tagatactgg ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt
     9661 ctcgaaaatg gtgaagttaa gattttcaga gcactcaacg aagccagcat ccgcaggtct
     9721 gatcgaacca tggtggcaga tattgtaata aatggtgttc cctttgaacg ttttcgtgga
     9781 gacgggctaa cagtttcgac accgactggt agtactgcct ataacaagtc tcttggcggt
     9841 gctgttttac accctaccat tgaagctttg caattaacgg agattgccag ccttaataat
     9901 cgtgtctatc gaacattggg ctcttccatt attgtgccta agaaggataa gattgaactt
     9961 attccaacaa gaaacgatta tcatactatt tcggttgaca atagcgttta ttctttccgt
    10021 aatattgagc gtattgagta tcaaatcgac catcataaga ttcactttgt cgcgactcct
    10081 agccatacca gtttctggaa ccgtgttaag gatgccttta tcggtgaggt ggatgaatga
    10141 ggtttgaatt tatcgcagat gaacatgtca aggttaagac ctttttaaaa aagcacgagg
    10201 tttctaaggg attgctggcc aagattaagt ttcgaggtgg agctattctg gtcaataatc
    10261 aaccgcaaaa tgcaacgtat ctattggacg ttggagacta cgttaccatt tacattcccg
    10321 ctgaggaagg ctttgaaacc ttggaggcta ttgagcatcc attagatatt ctctatgagg
    10381 atgaccactt tctagtcttg aataaaccct atggagtggc ttctattcct agtgtcaatc
    10441 actctaatac cattgccaat tttatcaagg gttactatgt caagcaaaat tatgaaaatc
    10501 agcaggttca cattgttacc agactagata gggacacttc tggcttgatg ctctttgcca
    10561 agcacggtta tgcccatgca cgattagaca agcagttgca gaagaaatct atcgagaaac
    10621 gctactttgc tttggttaag ggagatggac atttggagcc agaaggggaa attattgctc
    10681 cgattgcgcg tgatgaagat tccattatta ccagacgagt ggctaaaggc ggaaagtatg
    10741 cccatacttc atacaagatt gtagcttctt atggaaatat tcacttggtc tatattcacc
    10801 tgcacactgg tcgaacccat caaatccgag tccatttttc tcatatcggt tttcctttgc
    10861 tgggagatga tttgtatggt ggtagtctgg aagatggtat tcaacgtcag gctctgcatt
    10921 gccattacct atcctttaat catccatttt tagagcaaga cttgcagtta gaaagtccct
    10981 tgccggatga tttcagtaac cttattaccc agttatcaac taatactcta taaaaactgt
    11041 ctcagagtat aattattatc ttaaaggaga aaactcatgg aagtttttga aagtctcaaa
    11101 gccaaccttg ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga gcctcgtatt
    11161 cttcaagcaa caaaacgctt agtaaaagaa acagaagtga ttcctgtttt gcttggaaat
    11221 cctgaaaaaa ttaaaattta tcttgaaatt gaaggaatca tggatggtta tgaggtcatc
    11281 gaccctcaac attatcctca atttgaagaa atggtttctg ccttggtgga gcgtcgcaag
    11341 ggcaaaatga ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa ctactttggt
    11401 gtgatgttgg tttacttggg cttggttgat ggaatggtgt caggagcgat tcactcaaca
    11461 gcttcaacag ttcgcccagc tctacaaatc atcaaaactc gtccaaatgt aactcgtact
    11521 tcaggagcct tcctcatggt tcgtggtacg gaacgttacc tatttggaga ctgtgccatt
    11581 aatatcaatc cagatgcaga agccttggct gaaattgcca tcaactcagc aatcacagct
    11641 aagatgtttg gcatcgaacc taaaattgcc atgttgagct attctactaa aggttcaggg
    11701 tttggtgaaa gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct
    11761 gaccttgaaa tcgatggtga gttgcaattt gatgcggcct ttgttcccga aactgcagct
    11821 ctgaaagctc cgggaagtac agtagctggt caagcaaatg tcttcatctt cccaggtatc
    11881 gaggcaggaa atatcggtta caagatggct gaacgcctgg gtggctttgc ggctgtagga
    11941 cctgttttgc aaggtttaaa caagccagtt aatgatcttt ctcgtggatg taatgcagat
    12001 gatgtttaca agttgaccct catcacagca gctcaagcag ttcatcaata gtgaaaacta
    12061 taaagtaata tactatgcta tactgtagtt atgaaactat gtgcgaaaag cacttccatt
    12121 aactcctgag aactaaatta ctgattggtg tcaaaaagga caacttctaa gcgataatat
    12181 cctgtctata tacgacctat agaaatctgt aatatacatg tccgtaaaac gataaattcc
    12241 ctttttgatt ttaaatgagt atgaaaagag aattttttgg ctctttgtca actgtagtgg
    12301 gttgaagaaa agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag
    12361 agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg cattgcgttt
    12421 gataagtttg atgagattat tggtcgcttc caatttggcg tttgaatagg gtagttgaag
    12481 ggcgttgacg attttctctt tgtcctttag aaaggtttta aagacagtct gaaaaagagg
    12541 atgaacctgc tttagattgt cctcaataag cccgaaaaat ttctctggtt ccttattctg
    12601 gaagtgaaaa agcaagagct gatagtggtg tttcaagtct tccgaatagc tcaaaagctt
    12661 gtttaaaatc tctttattgg ttaagtgcat acgaaaaata ggacgataaa atcgcttatc
    12721 actcagttta cggctatcct gttgaatgag tttccagtag cgcttgatag ctttgtattc
    12781 atgggatttt cgatgaaact gattcatgat ttggacatgc acacgactca tagcacggct
    12841 aagatgttgt acaatgtgaa agcgatcaag aacgatttta gcattcggga gtgaaacagc
    12901 ctgggagact gtttcagcct gagcctagaa atttgaaagc gaagctgttt agccaagtca
    12961 tagtaagggc taaacatatc catagtaatg attttgacgc gacatcggac ggctctatca
    13021 tatttaagaa agtgatttcg gatgacagct tgtgttctgc cttcaagaac agtgataata
    13081 ttaagattat caaaatcttg cgcaatgaaa ctcatctttc ccttagtgaa ggtatactca
    13141 tcccaagaca taatctttgg aagccgagaa aaatcatgct caaagtgaaa gtcattgagc
    13201 ttgcgaatga cagttgaagt tgaaatggcc agctgatgag caatatcggt catagaaatc
    13261 ttctcaatca acttttgcgc aattttttgg ttgataatac gaggaatttg gtgatttttc
    13321 ttgacgatag aagtttcagc gaccataatt ttagaacaat gatagcactt gaaacgacgc
    13381 tttctaagga gaattctagt aggcatacca gtcgtttcaa gataaggaat tttagaaggt
    13441 ttttgaaagt catatttctt caattgattt ccgcact
//
LOCUS       DAVKZI010000051        12738 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKZI010000051 DAVKZI010000000
VERSION     DAVKZI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.052"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            468..761
                     /locus_tag="VXB18_001845"
                     /pseudo
     CDS             468..761
                     /locus_tag="VXB18_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            868..1219
                     /locus_tag="VXB18_001846"
                     /pseudo
     CDS             868..1219
                     /locus_tag="VXB18_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1495..2795
                     /locus_tag="VXB18_001847"
                     /pseudo
     CDS             1495..2795
                     /locus_tag="VXB18_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2841..3851)
                     /gene="tsaD"
                     /locus_tag="VXB18_001848"
     CDS             complement(2841..3851)
                     /gene="tsaD"
                     /locus_tag="VXB18_001848"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0383003.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMVAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3841..4278)
                     /gene="rimI"
                     /locus_tag="VXB18_001849"
     CDS             complement(3841..4278)
                     /gene="rimI"
                     /locus_tag="VXB18_001849"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0383004.1"
                     /translation="MIEIKRIQQRPDLAQAIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENLFEAEVLQIAVKEAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNHRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(4275..4958)
                     /gene="tsaB"
                     /locus_tag="VXB18_001850"
     CDS             complement(4275..4958)
                     /gene="tsaB"
                     /locus_tag="VXB18_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0383005.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDFDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLDLVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVAPF
                     VEQIQEYLPRTNFKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            5136..5321
                     /gene="cibA"
                     /locus_tag="VXB18_001851"
     CDS             5136..5321
                     /gene="cibA"
                     /locus_tag="VXB18_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0383006.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            5323..5475
                     /gene="cibB"
                     /locus_tag="VXB18_001852"
     CDS             5323..5475
                     /gene="cibB"
                     /locus_tag="VXB18_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0383007.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            6293..6526
                     /locus_tag="VXB18_001853"
     CDS             6293..6526
                     /locus_tag="VXB18_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0383008.1"
                     /translation="MIYKIFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6528..8207
                     /locus_tag="VXB18_001854"
     CDS             6528..8207
                     /locus_tag="VXB18_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0383009.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRNLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(8353..8442)
                     /locus_tag="VXB18_001855"
                     /pseudo
     CDS             complement(8353..8442)
                     /locus_tag="VXB18_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8631..10544)
                     /gene="mnmG"
                     /locus_tag="VXB18_001856"
     CDS             complement(8631..10544)
                     /gene="mnmG"
                     /locus_tag="VXB18_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0383010.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMILPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQDKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(10554..11009)
                     /locus_tag="VXB18_001857"
     CDS             complement(10554..11009)
                     /locus_tag="VXB18_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0383011.1"
                     /translation="MTQQNFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(11150..12271)
                     /gene="mnmA"
                     /locus_tag="VXB18_001858"
     CDS             complement(11150..12271)
                     /gene="mnmA"
                     /locus_tag="VXB18_001858"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0383012.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLGKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
BASE COUNT         3633 a         2972 c         2501 g         3632 t
ORIGIN      
        1 tttataatca tcaataacct ttgaatctct agatacgatt atcaaaatag gatatagaga
       61 catccttctg atctgctttt tacaaagtcc aattatatgc ggatctatac ctccacaatg
      121 tccattatta tacctaacta taatatgagc cgaaaacact atatccttaa tgtctccata
      181 tccatcaggg atattaatat ttatttttcc acaactatat tgcattgtaa ccatctcctt
      241 aaacgacgca ttatgatatt tgatagagaa atttttatga ataactcaat aattttatag
      301 taaatcatgc ttatatctca aagataccta ttttctcttg tctcgacctt ctccaaagaa
      361 ttgctataat actattacaa atacatctgc actacacttc aaattttagc actgtataaa
      421 aacgtttcaa cacactaact ttaagaaaac ttccactatt aattgaaaaa gttgatagag
      481 ataaattaaa gatctatatt gaaactcatc ccgatgctta tttgactgaa atagctgctg
      541 aattcaactg tcctccaaca actattcatt acgctctaaa ggctatggga tatagtctaa
      601 aaaagagctg tacctactgc gaacaagacc cagaaaaagt aaatcggttc cttaaagaat
      661 tgaatcactt aagctacctg actcctattt atatttatga gacaggggtt gagacctatt
      721 tttatctcga atatgatcga gccttgagca ggcagttagt ctctctggaa gaagatataa
      781 ttatttgaat taagatcgag acaacgcaca ccagagattg cgatactgtt atagaagtac
      841 taatgccctt ttttgtttca atatactatg gctccgatga cctataaaga tacgatgacg
      901 agtgactttt tcgaagcttg cttccaaaaa ttcttactac ctactttaga tacaccatcc
      961 cttatcatta tggacaatgc aaggtttcac agaatgaaca tgtgtaagga gcagggcata
     1021 gactgttacc acttcctacc tattcacccg agtataatcc cattgagaaa atatgggctt
     1081 acatcaaaaa catctcagaa taatattgtc aaattacgat gcttttcttg aggcactttt
     1141 gtcctattct tgtttcagcc gactatactc cgttattggg cagctacgga acagtcgatg
     1201 ggacgatggg gggacataaa aaaatcctcc agttttgttt tttataacag tatactggag
     1261 aattgacaat ctcggtagat acctcgttat agcgcggtta cttattaggc agttacaaaa
     1321 caactgtgaa cagaaaacat tccagagtca gacaagactt tggaatgttt tggctctata
     1381 atttctgtag tgggtaatcc caccccagga attatagggt cgtttcttgt agaaaaaaag
     1441 ccccatatga cctataatga aaagcgtcta accaactcat tagaaagggt tcatatggaa
     1501 caacttaaga ataccacaga tttgctcgga ttgaaagaca aaaatatcaa aatcttgtct
     1561 gttctgaaat accaaaccca tctagtcgtt caggcaaagt tggattcccc cgctcctcct
     1621 tgtcctcatt gtcaagggaa gatgatcaaa tacgacttcc agaaagcctc taaaattccg
     1681 cttctcgact gtcagggttt acccacggta ctgcatctca aaaagcgccg ctttcagtgc
     1741 aagaattgcc ttaaggtggt cgtttctcaa acatccattg tcaagaaaaa ttgccagatt
     1801 tccaacatgg tgagacaaaa aatcgctcag ctcctccttg aaaagcagtc tatgactgag
     1861 attgcccaca gattggcggt ctcaacttcc accgtcatcc gaaaactgag ggaatttaag
     1921 tttgaaaccg attggaccaa gttgccaaaa gttatgagtt gggatgagta tagcttcaaa
     1981 aagagcaaaa tgagcttcat tgcccaagat tttgagtcca aatccatcct cgcaatttta
     2041 gacgggcgaa ctcatgcggt gattcgaaac catttccaac gctatcagag agaggttcgg
     2101 gagctggtcg aggtcatcac catggacatg tacagccctt attatcggct cgctaagcaa
     2161 ctctttccaa aggcgaagat tgttcttgac cgcttccaca ttgtccaaca tctgagccga
     2221 gctatgaacc gagtacgaat ccaaatcatg aaccaatttg accgaaaatc cttggagtat
     2281 cgggcgctca agcgcttttg gaaccctcgc tttttcgttt ctaggctcgg gctaaatcag
     2341 tccactggac tgatttacta caccagtata gcttcaagct ctgtcagaaa cgattctatc
     2401 agcccacgtt tcgaatgcac ttaacccatc gggaagtacg agataagctg ctttcttact
     2461 ctgagggatt acaggttcac tacgaactct atcaactcct gctctttcat tttcaagaga
     2521 agaatgccga ccatttcttt ggattgattg agcaagaact gccaacggtt catccgcttt
     2581 ttcaaacggt cttttggact tttttaaggg atagagataa gattatcaac gcacttaagc
     2641 tgccttattc caacgctaaa cttgaagcga ccaataattt gattaagatt atcaagcgca
     2701 aagcctttgg tttccggaac tttaacaatt ttaaaaaacg gattttgatg actttgaaca
     2761 tcaaaaaaga gagtacgaat ttcgtactct ccagattgca gcttttcgcc tacccactac
     2821 acttgacaaa gagccactct ttattccatg gtatcaaagg caagacttgg tttggcattg
     2881 aggtcccagc ctgcgaagtt ttctttgttc cactcgctga cgctggcata ggcaatcata
     2941 cctgcattgt ctccgcagag tcgcagaggg gggatgataa ccttgacatc tgtgatttcg
     3001 gctgctaggc gttctctgag acctttattg gctgccacac cacctgccac aactagggtt
     3061 ttaacaggat atttctccaa agccttcttg gtttttgcca tgagaatgtc cataactgct
     3121 gcttggaagg aagcacacaa atcttctgta gacaggcttt ctcccttttg ctcggcattg
     3181 tgatgaagat tgataaaggc agatttcaaa cctgagaagg agaactccag attatcttcc
     3241 ttaatcatgg cacgggggaa atcataaata tcctgcccct gatgagccag ctcgtcaatc
     3301 tcacgacctg caggataggt caagcccatg acacgaccga ccttgtcata agcctcccca
     3361 actgcatcgt ctcgtgtctc cccaacaatc ttgtaatcgc cagcctcaga aacatagacc
     3421 aactctgtgt gcccaccact gactaaaagg gctagcaagg gaaactccaa aggctccaca
     3481 ctctgagcta ccatgaggtg cccagccatg tgattaacag gaatcagtgg aagtccgtga
     3541 gcccaagcaa aggccttggc agctgacaaa ccaactagca aggctccgac caagcctggt
     3601 ccgtaggtaa ccgcaacagc tgtcacgtcc tcttcggtaa tccctgcttc tgccaatgcc
     3661 tcctcgatac aggctgtaat gacctcgaca tggtgacgac tggctacttc gggcactacg
     3721 ccaccaaaac gtttgtgact ctcaatttga ctagcaatga cattggacaa gagctcatcg
     3781 tcgtttttca agacggcgac actggtctca tcacaggatg tctcaaatgc taaaatatat
     3841 ctatccttca tctatttctc tcttcataat gatggcgtcc tcgactgggt catggtagta
     3901 ggcctttcgc tcagcgatga ctgccatctt ttctttcttg taaaatgctt gcgctcgatg
     3961 atttgactgt ctgacttcaa ggaaaatttc cttgtctgtc ggcaattgag caaacaaggc
     4021 tgacgcaatt ccctgaccct gataggcttc tttgacagcg atttgcaaga cttctgcctc
     4081 aaaaagattc tcctgaacag ctagaaagcc aatcacttct gccccatcat aagccagaac
     4141 ataccaagtc tggtcttggg acaggtctgc ttggatttgt tccagcgtcc acggactaac
     4201 tgggtaaaca gctgccataa cagcgtagat ggcttgagcc aagtcaggtc gctgttggat
     4261 tcgtttgatt tctatcatag gcgtttaatg taagactcgc cagactctgt gtggttcttg
     4321 agccagtttt cctcagcctc aacacgtttg agataattcg gcacaaaatc atgcaaggag
     4381 tctgcttcct tgtcccaagc taaaagagca agattggctg catttggcaa ggtttctttg
     4441 aaattagtcc ttggcaagta ttcttgaatc tgctccacaa agggggcaac ttctccgaca
     4501 aaggttacct gactagcgcc cttgattagc tcaatgactc gctcaaaagg cagatgcgct
     4561 tctggcatga caggtttagc attttcataa aatcctgcat aaacattgtt gcgacgcgca
     4621 tccatcaaag gaacgaacaa gccttcttgt tgatatggca ccagatccaa gaggctagac
     4681 ataccaacta actcaatgtt cagagtatga gccaaggtct tggcagtggc taccgcaatt
     4741 cgcaaacctg tgtagctacc tggcccttca gccaccacga ttcggtcaaa atccttgggt
     4801 gtccaatcca aacttgccat caaaaaatcg atggcaggca taagggtaat actgtgattt
     4861 ttcttaatat taatcgtcgt ctcggcaaga acctgcttat cctctaaaat agccagagaa
     4921 agagccttgc tggacgtatc aaaagctaat actttcataa cacattccta tctttttgtc
     4981 tgcttactat tatactacaa aagatggcac atgggaattt tctttgcccc cagacaagag
     5041 tgccctcact taactaaaaa taatttaaaa aaatgctcac ttttcctttt cttttccgaa
     5101 tataaaagtg aacaagaaaa aaggaggaaa gttcaatgac aaattttgac attcttgaca
     5161 atcaattttt atccttatct gaaaatgaat tatcagatat tgatggcggt ctcgctccct
     5221 tggttatctt tggagtagca gtatcttgga aggctattgc aggtggaaca gcacttatag
     5281 gttctggttt ggcagctggt tattttttag gaggagatta atatgatgaa agatttgaac
     5341 aactatcgtg aaatttctaa taaggaattg caagaaatca agggtggctt tggtgtaggt
     5401 gttggtatcg ctttatttat ggcaggttat accattggaa aagaccttcg taaaaagttt
     5461 ggtaagtcat gctagataag aaacacattt ttagaaggat aaattttatt gtcttcatct
     5521 cttacagttt gctcagcatt ctcaatgatt tgaacattac tactatccct ttaccattcg
     5581 atttatctgt ttgtattgtt ttatttttat gcttcaactc tatttttgag cagaacaatg
     5641 actcccataa aaataataag ctttgaaaat tccattgtca tgtcatgtta gaaaaatgca
     5701 aagaccacct catcttgata gatggggtgg aattttcgtg tcgtaaatct actatctcta
     5761 catccccaaa caaaaaaaac cagcataagc agggcatcta agcatttaat ccaaagtaaa
     5821 atacaaacca aacgacatag gtcacgagga ggagaaaaag cgagtagaga gtcacaaagg
     5881 tcattttcca caagaacttg gtttgtcatc gttccagttt ggcaaataga agatttcctt
     5941 cataaacgca agcaacaaaa acgataaaag ctagcaaacg aactccgata acaaaagcaa
     6001 ataagttata catagggcaa cctccttgac ttaaaatcta tatggaatta tgacaagtaa
     6061 taaacttcac ttccgttatc aacataacac attttcttta tttttgcaaa cgcttaccga
     6121 agaaatcgtc ccctaacttt ctcgtttccg tcttttacta atttttcatt ttgtggtata
     6181 attgaaataa ttgtaacgaa tcaaggtcaa tctagacaca aaatggaatg aaatcaagca
     6241 aatatctgct aaaagtttgg aataagctga cctgtaaata gaaaggaact atatgattta
     6301 caaaattttt tatcaagaaa caaaagaacg tagcccacgc cgtgaaacaa cacgcgcgct
     6361 ttacctagac atcgatgcca gctcagaact tgagggccgt atcactgctc gccaacttgt
     6421 cgaagaaaat cgcccagagt acaatatcga atatatcgaa ctcttgtctg acaaattgct
     6481 cgattacgaa aaagaaactg gcgccttcga aattacggag ttctaatatg gcctacactc
     6541 ttaaacctga agaagtcggc gtttttgcca tcggtggtct aggagaaatc gggaaaaaca
     6601 cttacggaat tgaataccaa gacgagatta tcatcgtcga tgctgggatt aaattcccag
     6661 aagatgactt gcttggtatc gactatgtca ttcctgacta ctcttacatc gtggacaata
     6721 tcgaccgcgt caaggctgtt ttaatcacac acggacacga ggaccacatt ggtgggattc
     6781 cgttcctact caagcaagca aatgtcccta tctacgctgg accgcttgcc ttggctttga
     6841 tccgtgggaa actcgaagaa cacggcctct tgcgcaacgc caaactttac gaaatcaacc
     6901 acaacaccga gttgaccttt aaaaatctca aggcaacttt ctttagaacg actcactcta
     6961 ttccagagcc tttggggatt gtcattcata ctcctcaagg gaaaatcgtc tgtacgggtg
     7021 actttaagtt cgactttact ccagttggag aacctgcgga cttgcatcgt atggctgcgc
     7081 ttggtgaaga aggcgtgctc tgtctcctgt ctgactcgac aaatgcggaa gtaccaacct
     7141 ttaccaactc tgaaaaagtc gttggtcagt ccattatgaa gattatccaa ggtattgaag
     7201 gacgtatcat ctttgcatcc tttgcctcaa atatcttccg tctccagcag gcaacagaag
     7261 ctgctgttaa gactggacgc aagattgcgg tctttggtcg ttctatggaa aaggccattg
     7321 tcaacggaat cgatcttggc tacatcaaag ctcctaaggg aacctttatc gagccaaatg
     7381 aaatcaaaga ttatcctgca ggagaagttc ttatcctctg tacaggtagt cagggtgagc
     7441 ctatggcagc cctctctcgt atcgccaacg gaacccaccg tcaagtacaa ttacaaccag
     7501 gtgataccgt tatcttctct tctagtccca tccctggaaa cactactagc gtcaacaagc
     7561 tgattaacat catttctgaa gctggtgtcg aagttatcca cggtaaagta aacaatatcc
     7621 atacatctgg acacggtggt cagcaagagc aaaaactcat gctctgcttg attaagccaa
     7681 aatacttcat gcctgtccac ggtgaatacc gcatgcaaaa agtccacgct ggactagcag
     7741 tggatactgg tgttgagaag gacaatatct ttatcatgag caatggcgat gtgcttgccc
     7801 ttactgctga ctcagctcgt atcgcaggtc atttcaacgc ccaagatatc tatgtcgatg
     7861 gaaatcgtat cggtgaaatt ggcgcagctg tcctcaaaga tcgtcgcaat ctatctgaag
     7921 acggtgtcgt tctggcagtc gcaactgttg acttcaaatc gcagatgatt ctatctggtc
     7981 cagacatcct cagccgaggc tttgtctaca tgagagagtc tggcgacttg attcgccaaa
     8041 gccagcgtat cctcttcaat gccattcgta tcgcactgaa aaataaggat gctagcgtgc
     8101 aatctgtcaa tggtgccatt gtcaacgcta ttcgcccctt cctctatgaa aataccgaac
     8161 gtgaaccgat catcatcccg atgatcctca caccagatga agagtaatac tcttcaaacc
     8221 atgtcagctt cgccttgccg tatatatgtt actgacttcg tcagttctat ccacaacctc
     8281 aaaactgtgt tttgagctga cttcgtcagt tctatccaca acctcaaaac tgtgttttga
     8341 gctgacttcg tcagttctat ctacaacctc aaagcagtgc tttgagcaac ctacggctag
     8401 cttcctagtt tgctctttga ttttcattga gtacaagtca acaaaacagc cccgtcttcg
     8461 gagctgtttt tctctatgct ttcttttgag attaaaactc aatgaaaatc agaccagaag
     8521 gctaggaaaa tgcataactt gagttagctc ccatagttcg gggaactatg ggaggttgga
     8581 gatgaatcaa agccaagctt tgaactcatt cgtaagaagc cgacgacgta tcattttgat
     8641 ttttgaagag ttttagaaat actacgattt ttaccttcca gatacaccat caaaatagaa
     8701 atatctgctg ggttcactcc cgaaatacgg ctggcttggc cgatggtttc tggattgatg
     8761 agtttgaact tctgacgagc ttccgtcgca atagaatcga tgtcatccca gtcaatatta
     8821 gctggaatgc gtttttcttc catacgtttc atcttggcaa cctgatccat ggcttttgaa
     8881 atatagcctt cgtacttgat ttctgtttca atcaattcga taatcttatc atccaaatcc
     8941 tctgcagctg gtccgatgaa ggctaccaca tcttggtaag aaacttctgg acggcgaagg
     9001 aattccttgg ctgtcactgc atctgtcaag ggtttgaagc ccatctcctc aaccttagca
     9061 ttggtttcct tgactggctt gagtttgata ctgtctaggc gtttcatctc attatcaaat
     9121 tgatttttct tgatttcaaa acgagcccag cgttcatcat ccacaaggcc aatctcgcgt
     9181 cccatctcag tcaagcgcat atcagcattg tcatgacgga gaatgagacg gtattcagca
     9241 cgactggtca agagacggta gggttcgatg gttcccttgg tcaccaaatc atcaatcatg
     9301 accccaatgt aaccgtcact acgcttcaaa atcaactcag gcttatcttg gattttcaga
     9361 gccgcattga tccctgcgat aatcccttgg cctgctgcct cttcgtaacc tgatgttcca
     9421 tttgtctgac cagcagtgaa aagtcctgag attttcttgg tttccaaagt cgcacgcaac
     9481 tggtgaggca agatcatgtc atactcaata gcataacctg ttcgcatcat ctctgcattt
     9541 tccagacctt tgatggaatg aaccaagtca cgttggacat cctcaggcag actggttgaa
     9601 agtccttgga catagacctc ctctgtattg cgtccttctg gctcaaggaa gagttggtga
     9661 cgttccttgt ccgcaaagcg cacaatcttg tcctcaatcg atggacagta acgaggtccc
     9721 actcccttga ccacacctgt aaacataggc gcacggtgga ggttgttttg gataatctca
     9781 tgactggtac cattggtata ggtcaaccag catggcactt ggtccttgac ataatcctca
     9841 tcacgtgaag tgtatgagaa gtgattaggc gcttcatctc ctggttggat ttctgtcacg
     9901 tcgtagttga tagaagaggc cttgacacgt ggaggggttc ctgtcttgaa acgaccgatt
     9961 tcgagaccca gttccttgag attgtcagct aggttaatag aagccaagct gtggttagga
    10021 cctgatgagt acttgaggtc tccgatgata atttccccac ggagagcagt ccctgtcgtc
    10081 acaataacag ccttagcagc atattcttga tgggtggctg tacgcacacc gacaaccttg
    10141 ccatcttcca ccaaaatctc atcaatcatg gtttgacgaa gggtcagatt ttcttgattt
    10201 tcaactgtct tgcgcatctc cttagagtaa agttccttgt cagcctgcgc acgaagagca
    10261 cggacagctg gccccttccc tgtgttgagc atcttcatct ggatgtaagt cttgtcaata
    10321 gtcttggcca tctcgccacc gagggcatcg acttcacgca cgacaatccc cttggcagaa
    10381 ccaccgatag agggattaca aggcatgaaa gccagcattt caatattgat ggtcgcaagc
    10441 aggaccttac agcccatacg gctagcggcc aaggaagcct caaccccagc gtgtcccgca
    10501 ccaattacaa taatatcgta ttcttcagta aaatgataag tcatgtttct ctcctattcc
    10561 tcaagatgaa tgtgtcttag ttggccttcc caatctggta gggccgtttt taaaaaggct
    10621 ggaactagct ggatatcctc aagcttatcc aagtcaatcc actcacaggg ctgccttttc
    10681 tcatcttcct gcatggtcaa cggggcatct tcaagcaaat ccaccagata atgaaactcg
    10741 atattgtgat aggaaacgcc gtcttgttca aaacgatttt caaccacaaa agctagctgc
    10801 ccagcttgag ctttgacacc cagttcttcc ttcacttcac ggactaccgc gtcttccgtg
    10861 ctttcattga cttgaatcgc acctccaata gtgtaatact tgcccttgtc tttggtaact
    10921 agaagcttgt gattttggac aatcaaggct gtcgcccgaa caccaaaaac cgtattgtct
    10981 acttttgtcc gaaagttttg ttgagtcatt cttgtccttt cccttaaacg acacaaaaac
    11041 agtcaaaact acaaagaagt gcaggacaaa aaagcctgca acatccatga gctttgacca
    11101 tcatttctat tgctgttatt attgtagcaa attgagaaaa tttgtcaatc taaatgtact
    11161 gacaaacttg tccatcgcgg taagcattgt caatcaaacc accacctaga cactcttcgc
    11221 catcgtaaaa gacaactgcc tgtcctggtg taatcgcgcg ttgtggttcc gcaaagatga
    11281 cctctgcctt gtctcctttg acatggacgg tcaccttaga gtcaggctga cggtaacgga
    11341 atttagccgt acattctagc gtaaactctt ctggcatttc acgagtaaag tggacttgac
    11401 tggcttctag gctagttgac atgagcgaat catggtagaa tccttgtcct acatagagaa
    11461 tattcttgct tagatctttt ccgacaacga accaaggggc attgtcaccg ccgtgttgcc
    11521 caccgatacc gagtccgcca cgctgaccga ttgtatagta cataagacct gcatgctcgc
    11581 ccatatcgcg accatccaca gtcatcatgc gaccaggctg agctggcagg tagttgctga
    11641 ggaagttttt aaagttcttt tctccgataa aacaaatccc tgtcgaatct ttcttcttag
    11701 cagtcgaaag gcctgcttct tctgctagtc tgcgtacttc aggctttccc aaatgtccta
    11761 gtgggaacat ggttttttga agttgttctt gcgaaagttg gctgaggaaa taggtctgat
    11821 ccttgccatt gtccacgcca cgaagcatgt gaacggtacc atcctcatca cgcaccactc
    11881 gagcataatg cccagtcgct acatagtctg cccccaaggt tatggcatag tccaaaaagg
    11941 ccttgaactt gatttccttg ttgcacataa cgtccggatt tggcgtgcgc cctgcacggt
    12001 attccgctag gaaatactca aaaacgcggt cccagtactc tttttcaaaa ttgacagagt
    12061 agtagggaat gccaatctgg tctgccaccg caaccacatc cttgtaatct tcggtcgccg
    12121 tacagacgcc gttttcatct gtgtcatccc agttcttcat gaagataccg atcacatcgt
    12181 agccctgctc cttgagcaaa agagccgtca ccgacgaatc aacaccacca ctcatcccca
    12241 cgacaacacg tgttttagag ttatcactca tggtaagtct cccatctatt cgtttattca
    12301 cgattgaagg tcgtgtgtgc ttcacgattg aaggtcgctt gagcagtatt cattataaca
    12361 cgcttggtta gagaagacaa ggaagagctt aaaaattgtt ttttaaaact tatagtcaat
    12421 atacagatta tgtgaatgac gtgagtatac cttcttctta tcttcattca aataactata
    12481 ataaataaaa caacccattt tctctaatct atttttcaag ttagagaaaa ggagtcgttt
    12541 ttttaatgac atttcctgaa atcataagac aggtacctaa agaatacgaa cataaatcta
    12601 ttcaatcgaa ccttatcttt gtttcaaaat taaaatgtca aatgttctta acatgattta
    12661 atttaatcgg cttaaaccca ttcaccattg gcattgactt catagccatc tacagttgtg
    12721 ttgactgcaa gggcacct
//
LOCUS       DAVKZI010000052        11914 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKZI010000052 DAVKZI010000000
VERSION     DAVKZI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.053"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            723..1527
                     /locus_tag="VXB18_001859"
                     /pseudo
     CDS             723..1527
                     /locus_tag="VXB18_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     partial in the middle of a contig; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1680..1934
                     /gene="blpM"
                     /locus_tag="VXB18_001860"
     CDS             1680..1934
                     /gene="blpM"
                     /locus_tag="VXB18_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0383013.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATSGF"
     gene            1950..2153
                     /gene="blpN"
                     /locus_tag="VXB18_001861"
     CDS             1950..2153
                     /gene="blpN"
                     /locus_tag="VXB18_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0383014.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            2397..2630
                     /locus_tag="VXB18_001862"
     CDS             2397..2630
                     /locus_tag="VXB18_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="HEV0383015.1"
                     /translation="MDTKMMSQFSVMDNEMLVRTEDGDVSDIYRGYANQRSPFASYPS
                     ILKNSGPFPVSGYCLRGYHDRGYIGAGFHLCGI"
     gene            2662..3351
                     /locus_tag="VXB18_001863"
     CDS             2662..3351
                     /locus_tag="VXB18_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0383016.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVVVLHISFNVQTAKH
                     VQSTAEGWNVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3393..3626
                     /locus_tag="VXB18_001864"
     CDS             3393..3626
                     /locus_tag="VXB18_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383017.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3777..4388
                     /locus_tag="VXB18_001865"
     CDS             3777..4388
                     /locus_tag="VXB18_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0383018.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4549..5343
                     /locus_tag="VXB18_001866"
     CDS             4549..5343
                     /locus_tag="VXB18_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0383019.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5340..5975
                     /gene="trmB"
                     /locus_tag="VXB18_001867"
     CDS             5340..5975
                     /gene="trmB"
                     /locus_tag="VXB18_001867"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0383020.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6101..6580
                     /gene="rimP"
                     /locus_tag="VXB18_001868"
     CDS             6101..6580
                     /gene="rimP"
                     /locus_tag="VXB18_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0383021.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTHKKTVRIPYSLVSKARLAVKL"
     gene            6624..7760
                     /gene="nusA"
                     /locus_tag="VXB18_001869"
     CDS             6624..7760
                     /gene="nusA"
                     /locus_tag="VXB18_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0383022.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VTIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7782..8075
                     /locus_tag="VXB18_001870"
     CDS             7782..8075
                     /locus_tag="VXB18_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0383023.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8068..8367
                     /locus_tag="VXB18_001871"
     CDS             8068..8367
                     /locus_tag="VXB18_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0383024.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8384..11176
                     /gene="infB"
                     /locus_tag="VXB18_001872"
     CDS             8384..11176
                     /gene="infB"
                     /locus_tag="VXB18_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0383025.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11427..11777
                     /gene="rbfA"
                     /locus_tag="VXB18_001873"
     CDS             11427..11777
                     /gene="rbfA"
                     /locus_tag="VXB18_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0383026.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3708 a         2128 c         2683 g         3395 t
ORIGIN      
        1 tattataaaa ttggaaagca gtagggatgg gaagtactac cacagattta ttattaattt
       61 tatcagtatt gtttgaaatc caaaaaaagt atgttaagct atatttattt ggttctttag
      121 tttgattgtt gttgagtata actatttttg tatagatgaa aatcttgtta ttgttcaaga
      181 tgttttgatg accattcatg atttgagtaa tccaaggtca aaatgagtgc tatactagca
      241 gtgtaaagat tcttgttcaa ctaagataaa tcacacattt aggaggaaat tttatgaaga
      301 aaaaaatact tatcattttc atcttgtatc taatcatgtc catctttctt tatccgctta
      361 gggaaagtat ttggtatcag ctattttata ccatagccta tgtgattgca gttatgatct
      421 attttgcttt aactaaaaag aaaggagcaa agaaatgaaa acttttcttg ctaaaaaacg
      481 gaacatcttc ctttcgtttg ggggttgaag tattataaaa agtagaagtt aatgaagtat
      541 aaaagggtaa gtgtttttgc aatacttacc cttttataat agattccctg cgaaacaaaa
      601 tatggtatag tatagtagat tgaaactaga atagtacgcc tctacttcta aaacattgtt
      661 agaaatcgat ttgactgtcc tgattgattt atcctgttct tatttcattt tactatagtt
      721 ctatgaatta tgaaggaagt aaacaactaa ctgatgcacg atttaaatgt cttgttggtg
      781 ttcaacgcac gacttttgaa gagatgttag ctgtattaaa aacagcttat caacttaaac
      841 acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ccttcttatg gccactcttc
      901 actatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt atccacgaaa
      961 gcaacttact ccgtcggagc caatgggttg aagtaactct tgttcaaagt ggtgttacga
     1021 tttcaagaac tcctctcagc tctgaggaca cggtaatgat tattgatgcg acggaagtat
     1081 aaatcaatcg ccctaaaaaa agaattagcg aattattctg gtaaaaagaa atgccacgct
     1141 atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctttgga tatcactgtg
     1201 aactattgtc atgatatgaa gttgttcaaa atgagtcgca gaaatatcgg acaagctggt
     1261 aaaatcttga ctgacagtga ttatcaaggg cccatgaaga tatatcctca agcacaaatt
     1321 ccacgtaaat ccagcaaact caagccacta acagctgaag ataaagccta taaccatgcg
     1381 ctatctaagg agagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaatg
     1441 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct
     1501 ggtattatca atcatgaact aggattttgg tttcgcagga agtctaatgt aatttttgca
     1561 attcaagacg tttcgatgac tattcaagat ctggatgaaa aattttaaaa aacgatgata
     1621 tactaaactt gtcaaagtta caacaagaca aaaattaaaa ataaaaaaga gtatttgtca
     1681 tggatacaaa aattatggaa caatttcatg aaatggatat aactatgtta tctagtattg
     1741 aaggaggcaa gaataattgg caaactaatg tcttagaagg tggtggtgct gcttttggtg
     1801 gctgggggtt agggacagct atttgtgctg cgagtggtgt tggagcgcca tttatgggag
     1861 catgtggata cataggagct aaatttggtg tggctctttg ggcaggagta acaggggcaa
     1921 cgagtggatt ttaacaaaag gagacttgta tgaatactta ttgtaatata aatgaaacaa
     1981 tgctgagtga ggtttatgga ggtaattccg gaggagcagc tgtagttgct gctttaggtt
     2041 gtgcagcggg tggagtgaaa tatgggagac ttctaggacc atggggcgct gcaataggag
     2101 gaattggagg agcagtggtt tgtggatatt tagcctatac cgctacatca taaaaatgaa
     2161 agctaaattt tatgaaggct atattcttta ttattctctt cgcttttcaa acctatctta
     2221 tttatctatc cataagtatc tccgataaaa aacaaaagac tattgaatta acatcattga
     2281 attgttttgt catattattt ctaatctatg ataaattaat ttttctcttt attgcttatg
     2341 tttttttgat aatttttata ttaaacttgt tccgtaactg aaaagtgata tactatatgg
     2401 atacaaaaat gatgtcacaa ttttctgtta tggataatga aatgcttgtt cgtacagagg
     2461 atggggatgt ctctgatatt tatagagggt acgctaatca gagaagtcca ttcgcttctt
     2521 acccttctat attaaaaaat tcaggtcctt ttccagtaag tgggtactgc ctgcgtggtt
     2581 atcatgaccg tggttatata ggagcaggtt ttcatttatg tggaatatag gctgaaatac
     2641 aagaaatgag ggaggatttc tatgaaaaag tatcaacttc tattcaaaat aagtgcagtc
     2701 ttctcttact tatttttcgt atttggtctt tctcagctga cgcttatcgt ccaaaattat
     2761 tggcaatttt cttcccagat tggcaatttc gtctggattc aaaatatctt gagtttacta
     2821 tttagcggag tcatgatttg gattctggtt aagacaggcc atggctatct ctttcgcatt
     2881 ccaagaaaaa aatggctttg gtattctatt ttgacagtat tagtggtagt gctccatatc
     2941 tcttttaacg ttcagacagc taaacatgtt cagtcaactg ctgagggttg gaacgtattg
     3001 attggttata gtgggaccaa ctttgctgag ctaggtatct atgtaaccct gtttttcctg
     3061 actccactaa tggaagagtt gatttatagg ggattacttc aacacgcctt ctttaagcat
     3121 tcgcgatttg gccttgattt gcttcttcct tccattttgt ttgctcttcc tcattttttg
     3181 agtctgccta gtctgttaga tatcttcgtc tttgcaacat ttggaatcat ctttgccggt
     3241 ttgacccgct ataccaagag tatttatcca tcctatgcgg tgcatgtgat caataatatt
     3301 gtagcgacct tcccgttttt gctcactttt ctacataggg tcttggggta aaaaaacaaa
     3361 aggcttgctt ttcagccata gaggaggtca tcatgtataa acacttattt ttcctagatt
     3421 ccaaaacttt agatcggttg acaccctata ttctagtctt ggcttctgac accattgctt
     3481 ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt taatttccta aattccatgc
     3541 tagctttaat ggctatattc ataggggctg gctatgtggt cggattttgg ttactaatac
     3601 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa
     3661 ggcgacgttg acgtggtttg aatttgattt tcgaagagta taaaatggtt tgttttggaa
     3721 aggctagaac taaagaatga cgtgtaggaa gtctgtttgt tgaggaggat aattttatgg
     3781 agttttttga taaatttcat gccttgtgtt ttggattttt agtactaata attgtcatta
     3841 cagttcctta tacgattaac catggggatt tttttcaaaa tgaatctgca ttgattattg
     3901 taagtcttct tgtaacctcg ctgagtgttg cttatgctag aaagtttgaa atgatttctt
     3961 ttgggatgtt aagcaagaaa caacttttgc ttttcattgc aatctttctt ctaagtgtac
     4021 ttgagacgct ggtttatatt catttcttcg ctgtttcttc tggctcaggg gtccaacact
     4081 tggcggaagt cagcagagga atttccctgt ctttgatttt gactacctca gtttttggcc
     4141 ccatccagga ggaactcatt ttcagaggac ttcttcaagg tgcggttttt gacaattctt
     4201 ggttagggct tgtgctaact tcctctctct tttctttcat gcatggacct tctaatgtcc
     4261 cttcgtttat tttttatcta cttgggggct tgttgctggg ccttgcttat aaaaagagcc
     4321 aaaacctatg ggtttctact ctagtccaca tgttttacaa cagttggcca ctcctatatt
     4381 atttataaaa attatgaaaa ggtaagcaga agacggtgct tacctttttc aagctataat
     4441 gatacccaag ccaatccaga ggcttttctt tgagaatcgg gttagagtgg ttgacgaata
     4501 ggccaaaaac tagtagaata gtaaggaaac tttatacgga ggaaagaaat ggatttgggt
     4561 gataatgagc taacactgac tcccatacct gggaaaagtg gcaaggctta tatgggtagc
     4621 tatcctgatg ggaagcgcat ctttgtaaaa atgaacacct ctccaatcct acctggtcta
     4681 gctagagaac aaattgctcc acaattatta tggagtcgtc gtttggcaga tgggcgtgat
     4741 atgtgtgctc aagaatggtt gacaggcaag atattgaccc cctatgatat gaatcgtaag
     4801 caaatcgtca atattttaac ccgtcttcat cgctcacgtc cgttgatgac acaattgagt
     4861 cgtttgggct atgccatgga aacacctgta gatttactac agtcttggca agaaacggct
     4921 ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga tggctgattt gcgtcagact
     4981 attccaggat ttagagagga ccatgcgacc attgtccatg gagatgtacg acatagtaat
     5041 tggattgaga cagatagtgg cttgatttat ttagtagatt gggattcggt tcgcttgacc
     5101 gatcgcatgt ttgatgtggc ccatatgctc tgccattata tttcagaaca tcagtggaag
     5161 gaatggttga cctactacgg ttacaagtac aatcaaacgg tattaagtaa attgtattgg
     5221 tatggtcaat tgtcttattt gagtcagatt tccaagtatt atatgaacca agatttagaa
     5281 aatgtcaatc gggagattca tggtttgcgt catttccgag acaagtatgg aaagagaaga
     5341 tgagagttag aaatcgtaaa ggggcaacag aattactaga ggcaaatccc cagtatgtgg
     5401 tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt gtttggcaat gataatccca
     5461 ttcatgtgga agttggaagt ggaaagggtg cctttgtttc aggtatggcc aagcaaaacc
     5521 ctgacatcaa ctatatcggg attgatattc aaaagtctgt tttgagctac gctttggaca
     5581 aggtgcttga agttggagtg cctaacatca agctcttgtg ggtagatggt tctgacttga
     5641 ctgactactt tgaagacggt gagattgatc gcttgtatct gaacttttca gatccatggc
     5701 cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac ctttttggac accttcaaac
     5761 gtatcttgcc tgaaaatgga gaaattcatt tcaaaacgga taaccgtggc ttgtttgagt
     5821 acagtttagt gagcttttct caatatggca tgaaactcaa tggtgtctgg ctagatttgc
     5881 atgccagtga ttttgaaggc aatgtcatga cagaatacga gcaaaaattc tcaaacaagg
     5941 ggcaagttat ctaccgagtt gaggcagaat tttaagagat agcctaaaat taggctgtac
     6001 aagtgctttt gctttacata agttggcaaa cgtgctatac tgatagtaag aatatgaaaa
     6061 gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat
     6121 cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa gctccttttg aactcgtgga
     6181 tatcgagtat ggaaagattg gcagtgacat gattctcagt atttttgtag ataaacccga
     6241 aggaattacc ttgaacgaca cggcagactt gacagaaatt atcagtcctg tcctagacac
     6301 catcaagcca gatcccttcc cagaacaata tttcctagaa attaccagtc caggcttgga
     6361 acgtcctttg aaaaccaagg atgccgtcgc tggagcggtt ggaaaataca tccatgtcgg
     6421 actctaccaa gccatcgata agcaaaaggt ctttgaagga actttgttgg ccttcgaaga
     6481 ggacgagttg actatggaat atatggacaa gacgcataag aaaaccgtcc gaattccata
     6541 cagtttagta tcaaaagcac gtttagcagt taaattatag aaaaagaaag gatagctttt
     6601 gaggattcaa aagtgaagaa aacatgagta aagaaatgct agaggccttc cgcattttgg
     6661 aagaagacaa gggaatcaaa aaagaagata tcatcgacgc agtagtagag tcgcttcgtt
     6721 ccgcttatcg cagacgctat ggtcagtcag acagcgtaac tattgacttc aacgaaaaaa
     6781 caggtgactt tacagtttat actgtccgtg aagttgttga tgaagtattt gatagccgtt
     6841 tggaaatcag cttgaaagat gctcttgcca ttaattcagc ttatgaactt ggagacaaaa
     6901 tcaagtttga agaagcacca gctgagtttg gtcgtgtagc agcccaatct gccaaacaaa
     6961 ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac ttacaatact tacaaagaac
     7021 atgagcaaga aatcatgtct ggtacagtag aacgctttga caaccgcttt atctatgtca
     7081 accttggtag catcgaagcc caattgtcaa aacaagacca aattcctgga gaagtttttg
     7141 cttctcatga tcgtatcgaa gtttatgttt acaaggttga agacaaccct cgtggtgtga
     7201 acgtctttgt tagccgtagc catccagaaa tgatcaaacg tttgatggag caagaaattc
     7261 cagaagttta tgatggaact gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta
     7321 cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc tatcggtaca atcgttggac
     7381 gtggtggtgc taatatcaag aagattacta gcaaattcca cccagctcgt tacgatgcta
     7441 aaaatgaccg catggtacca atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc
     7501 cagctgaatt tatctacaat gccatcgctc ctgctgaggt tgaccaagtt atctttgatg
     7561 aaaacgacag caaacgtgcc ttggtggttg ttccagataa caagctttct cttgccattg
     7621 gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt atcgatatca
     7681 agtctgctag cgaatttgaa gccatggaag acgctgcttc agtagagttg gaagtagaaa
     7741 acgatactgt agaagaataa aagctgctag aggagggaaa gatgaaaaca agaaaaatcc
     7801 ctttgcgcaa gtctgttgtg tctaacgaag tgattgataa gcgtgatttg ctccgcattg
     7861 ttaagaacaa ggaaggacaa gtctttattg atcctacggg caaggccaat ggccgcggcg
     7921 cttatatcaa actagacaat gcagaagccc tagaggcgaa aaagaagaag gtctttaacc
     7981 gcagctttag catggaagtg gaagaaagct tttatgacga gttgatcgct tatgtggatc
     8041 acaaagtgaa aagaagagag ttgggacttg aataagcaaa agataagtaa tctcttgggg
     8101 cttgctcagc gagcagggcg catcatatcg ggtgaagaat tggtggtcaa ggccattcaa
     8161 gacggcaagg ccaagttggt ctttctagct catgatgctg gacccaatct ggccaagaag
     8221 attcaagata aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc aacactggaa
     8281 ttaagcatag cagtcgggaa atcgagaaag gttttggctg taacagatgc tggatttaca
     8341 aagaaaatga ggtctcttat ggaatagaag aggaggacat gatttgtcta agaaaagatt
     8401 gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga
     8461 gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat
     8521 tgctgccagc tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa
     8581 agtaagtgca gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg tagctaagga
     8641 agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa aaagtagcag cgaaaccgca
     8701 aagccgtaat ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag aacgacgtaa
     8761 gcaaaataag ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg
     8821 acgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc
     8881 taagaagcag caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag aggacaaacg
     8941 ttcaaatcaa gtggctccac gtattgactt taaagcccgt gcagcagccc taaaagcaga
     9001 gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc aagcagtatc aggctgctaa
     9061 agaagccttg gctcaagcta acaaacgcaa ggaaccagag gaaatctttg aagaagcggc
     9121 taagttagct gaacaagcac agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa
     9181 agaacctgca gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga
     9241 ttatgatcat gaagaagatg gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca
     9301 agtgagaaat caaaagaata gtaactggaa taacaacaaa aagaacaaaa aaggcaataa
     9361 caagaacaac cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc atgaattgcc
     9421 aacagaattt gaatatacag atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg
     9481 tgaaccagct gaaattgtta agaaactttt catgatgggt gtcatggcca cacaaaacca
     9541 atccttggat ggggaaacaa ttgaactcct catggtggat tacggtatcg aagccaaaca
     9601 aaaggttgaa gtggataatg ctgacatcga acgtttcttt gtcgaagatg gttatctcaa
     9661 tgaagatgaa ttggttgagc gtccaccagt tgttactatc atgggacacg ttgaccacgg
     9721 taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg
     9781 tattactcag catatcggtg cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct
     9841 tgatacacca ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga
     9901 tattacgatc ttggtcgtag cggcagatga cggggttatg cctcagacta ttgaagccat
     9961 caaccactca aaagcagcta acgttccaat catcgtagct attaacaaga ttgataaacc
    10021 aggtgctaac ccagaacgcg ttatcggtga attggcagag catggtgtga tgtcaaccgc
    10081 ttggggtgga gattctgaat ttgttgaaat ctcggctaaa ttcaaccaaa atatcgaaga
    10141 attgttggaa acagtccttc ttgtggctga aatccaagaa ctcaaagcag acccaacagt
    10201 tcgtgcgatc ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac
    10261 ccttcttgta caacaaggta ccttgaatgt tcaagaccca atcgttgtcg gaaatacctt
    10321 cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc
    10381 aacaccagtc tctatcacag gtttgaacga agcaccgatg gcgggtgacc actttgccgt
    10441 ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag cgtgccaaac gtgccctcat
    10501 gaaacaacgt caagctaccc aacgtgttag ccttgaaaac ctctttgata cccttaaagc
    10561 tggggaactc aaatctgtta atgttatcat caaggccgat gtacaaggtt ctgttgaagc
    10621 cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta tcgtccactc
    10681 agcggtcggt gctatcaacg aatcagatgt gacccttgcc gaagcttcaa atgcctttat
    10741 cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa caagcagaag ctgacgatgt
    10801 ggaaatccgt cttcacagca ttatctacaa ggttatcgaa gagatggaag aagctatgaa
    10861 agggatgctt gatccagaat ttgaagaaaa agttattggt gaagcggtta tccgtgaaac
    10921 cttcaaggtg tctaaagtcg gaactatcgg tggatttatg gttatcaacg gtaaggttgc
    10981 ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg gtgaactcgc
    11041 aagcttgaaa cactataaag acgacgtgaa agaagtgaca aacggtcgtg aaggtggatt
    11101 gatgatcgac ggctacaatg atattaagat ggatgatgtg attgaggcgt atgtcatgga
    11161 agaaatcaag agataagatt ttttgctcct ttcttaggtg gtgagggacg caagcaaacc
    11221 gatggtttca ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg atgggactga
    11281 taaatcagtt ccatcacttt caccacggcg aaagaagcag atgacttcaa attgaacttc
    11341 gtttcaattt aaactgaaaa tcaagaagtt taaaatagct aggtctgctg gcctagcttt
    11401 tggttcaaag tagagaaagg aatatcatgg caaatcattt ccgtacggat cgtgtgggca
    11461 tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc
    11521 aaggtgtgac catcacagat gttcagatgc tgggtgactt gtctgttgcc aaggtttatt
    11581 acaccatttt gagtaacctt gcttcggata accaaaaagc ccaaatcggg cttgaaaaag
    11641 caactggtac catcaaacgt gaacttggtc gcaatttgaa attgtacaaa atcccagatt
    11701 tgaccttcgt caaagacgag tccatcgagt atggaaacaa gattgacgag atgctacgca
    11761 atctggataa gaactaaaga agaggggttg cccctctttt ttggtggagg aaaataggtt
    11821 gaatttgaaa tggaaaaata ttcttttaaa atatattgaa actagaatag tacgccttta
    11881 cttctaaaaa attgttagaa atcgatttga ctgt
//
LOCUS       DAVKZI010000053        11836 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKZI010000053 DAVKZI010000000
VERSION     DAVKZI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11836
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.054"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(136..1767)
                     /locus_tag="VXB18_001874"
     CDS             complement(136..1767)
                     /locus_tag="VXB18_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0383027.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2060..7000
                     /locus_tag="VXB18_001875"
     CDS             2060..7000
                     /locus_tag="VXB18_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0383028.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSRANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EFNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKAAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7090..8286
                     /locus_tag="VXB18_001876"
     CDS             7090..8286
                     /locus_tag="VXB18_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0383029.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8422..8949
                     /locus_tag="VXB18_001877"
     CDS             8422..8949
                     /locus_tag="VXB18_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0383030.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9026..9382
                     /gene="glnR"
                     /locus_tag="VXB18_001878"
     CDS             9026..9382
                     /gene="glnR"
                     /locus_tag="VXB18_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0383031.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9419..10765
                     /gene="glnA"
                     /locus_tag="VXB18_001879"
     CDS             9419..10765
                     /gene="glnA"
                     /locus_tag="VXB18_001879"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0383032.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10861..10980)
                     /locus_tag="VXB18_001880"
     CDS             complement(10861..10980)
                     /locus_tag="VXB18_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0383033.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11469..11836
                     /locus_tag="VXB18_001881"
                     /pseudo
     CDS             11469..11836
                     /locus_tag="VXB18_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3799 a         2164 c         2554 g         3319 t
ORIGIN      
        1 tttagaaata gaggtgtact attctagttt caatatacta tatatctgca gaatactctt
       61 tcagcttcat tcagcctagt cttgcttagg aaaaagtaaa aagccatcca attatgatgg
      121 atagcttctt ggttcttaga tttgttctgc aaaaaccttt tcagcaaggt tcatagcgtg
      181 gtctgataca cgagtgtagt gtgagatgat gtcgataaag ttgaccccag cttgtgttga
      241 acattcgcct ttgttgaggc gtttgatgtg ggtttttctg agaacacgtt ctatcttatt
      301 gattgcttca tgacgttcta caagactgcg tgctttttca atatcattgt tttccacact
      361 atccagagca tctttgataa agtcactagt ttggcggtaa acttcctcta attctttcaa
      421 ggcggcatca gaaaattcaa catttttccg ttgaagatag tcagtcagat tgagtagagc
      481 ctccgtgtgg tctccaatcc gttccaaatc acgggaggaa tcaaggatat tggtgagcac
      541 ttcactttct ttttggctga gagcttcgct tgaaagggca atgagataac gtgttaattg
      601 ctcatcgatg gtgttaattg cttcttcggt tttatgccct ttttcagcaa ctttttcatc
      661 caagtcaatg atgtacttat aggaaaggtc aaaggcttta gcagcgtagt ttcctaagtg
      721 caagagctct tttttagcat ttcctagagc gatagatggg gcttgtttga tgaaatgttc
      781 atcaagatat aagggttcgt atttgacaac ctcgtcctct ccaggaataa tcttggttac
      841 aaagtaagcc agagctccga taaatggaaa ttggacaatg gtgttggtaa tattaaaggt
      901 tccgtgagca aaggcgatgg tcatttccgg tgctagattt agcgtagctt caaaccaatg
      961 aatcaggaca gtaaaaggaa ctagaaaaat aacgcagaca actgttccga taacgttgaa
     1021 ggcaacatga gctcctgcta cccgtttagc tgcaatatta gcccctaaag aggcaatgat
     1081 ggctgtaatg gttgtcccga tattgtcacc aaatagaact ggcaaagctc cctgtaggtc
     1141 aattagattg ccggcgtaga ggttttgtaa aatcccaatg gtagccgaag aagcttgaat
     1201 tagcaaggtc aagccagtac cgacaaagac acccaaaaca ggattcttac ttagctcaat
     1261 catatagtcc ttaaagacct gtaaatcctt gagtggagcc attgcgccgc tcataagatt
     1321 gagggcaaaa aagataccac cgacaccaaa gaggatgcgt ccgatattat tgactgtccg
     1381 atttttcgta aaaaagagac agacggcacc gataaagagc ataggtaggg catagttacc
     1441 taatttaaaa ccgatgagaa aggatgtgac agttgtccca atattagcac ccatgacaat
     1501 cccgatagcc tgacgtaagg ttaagagacc ggcactgacc aggccgactg tgataactgt
     1561 tacaccagaa ctagactgaa ttagagcagt catcccaata ccaaccagaa ctccaaagaa
     1621 aggattacta gtatatttgt caatgtaaaa acgaaggcga tctccagcag cttgttgcaa
     1681 accgtctccc atggtcttga tactatataa gaatagcccc agaccaccta aaaagtgaaa
     1741 taaaatttcc tgccaattaa tggacatttc tttttcctcc gaaaaataat cgcggaatat
     1801 ctcctattct attttaaagg ataaaagtaa atctaacaag tgttaatgtc aagtttgtaa
     1861 aagaaaatta taattgataa gtgtattatt tttaagagtt tttaacctta ttttagattt
     1921 gtgaaaacag ctattgtttt ttgtctaaaa atgttttagg ataaaaatgt gattatcatg
     1981 gttctagagt ttgataaaaa actacagaat ataaagcgct ttcttgaaaa caacaaaatc
     2041 aatcttttag gaggagaaaa tgaagaatcc attttttgaa agacgttgtc gttacagtat
     2101 tcgtaagtta tcagtaggag cctgctcgct gatgattggt gctgttttat ttgctggtcc
     2161 agccttggct gaagaaactg cagttcctga aaatagcaga gctaatacag agcttgtttc
     2221 aggagagagt gagcattcga ccaatgaagc tgataagcag aatgaagggg aacatgctag
     2281 agaaaacaag ctagaaaagg cagaaggagt agcgacagca tctgaaactg cagaagcagc
     2341 tagcgcagct aaaccagagg aaaaagcaag tgaggtggtt gcagaaacac catctgcaga
     2401 agcaaaacct aagtctgaca aggaaacaga agcaaagccc gaagcaacta accaagggga
     2461 tgagtctaag ccagcagccg aagctaataa gactgaaaaa gaagtccagc cagatgtccc
     2521 taaaaataca gaaaaaacat taaaaccaaa ggaaatcaaa tttaattctt gggaagaatt
     2581 gttaaaatgg gaaccaggtg ctcgtgaaga tgatgctatt aaccgcggat ctgttgtcct
     2641 cgcttcacgt cggacaggtc atttagtcaa tgaaaaagct agcaaggaag caaaagttca
     2701 agccttatca aacaccaatt ctaaagcaaa agaccatgct tctgttggtg gagaagagtt
     2761 caaggcctat gcttttgact attggcaata tctagattca atggtcttct gggaaggtct
     2821 cgtaccaact cctgacgtta ttgatgcagg tcaccgtaac ggggttcctg tatacggtac
     2881 actcttcttc aactggtcta atagtattgc agatcaagaa agatttgctg aagctttgaa
     2941 gcaagacgca gatggtagct tcccaattgc ccgtaaattg gtagacatgg ccaagtatta
     3001 tggctatgat ggctatttca tcaaccaaga aacaactgga gatttggtta aacctcttgg
     3061 agaaaagatg cgccagttta tgctctatag caaggaatat gctgctaagg taaaccatcc
     3121 aatcaagtat tcttggtacg atgccatgac ctataactat ggacgttacc atcaagatgg
     3181 tttgggagaa tacaactacc aattcatgca accagaagga gataaggttc cggcagataa
     3241 cttctttgct aactttaact gggataaggc taaaaatgat tacactattg caactgccaa
     3301 ctggattggt cgtaatcctt atgatgtatt tgcaggtttg gaattgcaac agggtggttc
     3361 ctacaagaca aaggttaagt ggaatgacat tttagacgaa aatgggaaat tgcgcctttc
     3421 tcttggttta tttgccccag ataccattac aagtttagga aaaactggtg aagattatca
     3481 taaaaatgaa gatatcttct ttacaggtta tcaaggagac cccactggcc aaaaaccagg
     3541 tgacaaagat tggtatggta ttgctaacct agttgcggac cgtacgccag cggtaggtaa
     3601 tacttttact acttctttta atacaggtca tggtaaaaaa tggttcgtag atggtaaggt
     3661 ttctaaggat tctgagtgga attatcgttc agtatcaggt gttcttccaa catggcgctg
     3721 gtggcagact tcaacagggg aaaaacttcg tgcagaatat gattttacag atgcctataa
     3781 tggcggaaat tcccttaaat tctctggtga tgtagccggt aagacagatc aggatgtgag
     3841 actttattct actaagttag aagtaactga gaagaccaaa cttcgtgttg cccacaaggg
     3901 aggaaaaggt tctaaagttt atatggcatt ctctacaact tcagactaca aattcgatga
     3961 tgcagatgca tggaaagagc taaccctttc tgacaactgg acaaatgaag aatttgatct
     4021 cagctcacta gcaggtaaaa ccatctatgc agtcaaacta tttttcgagc atgaaggtgc
     4081 tgtaaaagat tatcagttca acctaggaca attaactatc tcggacaatc accaagagcc
     4141 acaatcgccg acaagctttt ctgtagtgaa acaatctctt aaaaatgccc aagaagcgga
     4201 agcagttgtg caatttaaag gcaacaagga tgcagatttc tatgaagttt atgaaaaaga
     4261 tggagacagc tggaaattac taactggctc atcttctaca actatttatc taccaaaagt
     4321 tagccgctca gcaagtgctc agggtacaac tcaagaactg aaggttgtag cagtcggtaa
     4381 aaatggagtt cgttcagaag ctgcaaccac aacctttgat tggggtatga ctgtaaaaga
     4441 taccagccta ccaaaaccac tagctgaaaa tatcgttcca ggtgcaacag ttattgatag
     4501 tactttccct aagactgaag gtggagaagg tattgaaggt atgttgaacg gtaccattac
     4561 tagcttgtca gataaatggt cttcagctca gttgagtggt agtgtggata ttcgtttgac
     4621 caagccacgt accgttgtta gatgggtcat ggatcatgca ggggctggtg gtgagtctgt
     4681 taacgatggc ttgatgaaca ccaaagactt tgacctttat tataaagatg cagatggtga
     4741 gtggaagcta gctaaggaag tccgtggcaa caaagcacac gtgacagata tcactcttga
     4801 taaaccaatc actgctcaag actggcgctt gaatgttgtc acttctgaca atggaactcc
     4861 atggaaggct attcgtatct ataactggaa aatgtatgaa aagcttgata ctgagagtgt
     4921 caatattccg atggccaagg ctgcagcccg ttctctaggc aataacaagg tacaagttgg
     4981 ctttgcagat gtacaggctg gagcaactat taccgtttat gataatccaa attctcaaac
     5041 tccgctcgca accttgaaga gcgaagttgg aggagaccta gcaagtgcac cattggattt
     5101 gacaaatcaa tctggtcttc tttattatcg tacccagttg ccaggcaagg aaattagtaa
     5161 tgtcctagca gtttccgttc caaaagatga cagaagaatc aagtcagtca gcctagaaac
     5221 aggacctaag aaaacaagct acgccgaagg ggaggatttg gaccttagag gtggtgttct
     5281 tcgagttcag tatgaaggag gaactgagga cgaactcatt cgcctaactc acgcaggtgt
     5341 atcagtatca ggttttgata cgcatcataa gggagaacag aatcttactc tccaatattt
     5401 gggacaaccg gtaaatgcta atttgtcagt gactgtcact ggccaagacg aagcaagtcc
     5461 gaaaactatt ttgggaattg aagtaagtca ggaaccgaaa aaagattacc tagttggtga
     5521 tagcttagac ttgtctgaag gacgctttgc agtggcttat agcaatgaca ccatggaaga
     5581 acattccttt actgatgagg gagttgaaat ttctggttac gatgctcaaa agactggtcg
     5641 tcaaaccttg acgcttcgtt accaaggtca tgaattcaat tttgatgttt tggtatctcc
     5701 aaaagcagca ttgaacgatg agtacctcaa acaaaaatta gcagaagttg aagctgctaa
     5761 gaacaaggtg gtctataact ttgcttcacc agaagtaaaa gcagctttct tgaaagcaat
     5821 tgaagcggcc gaacaagtgt tgaaagacca tgaaactagc acccaagatc aagtcaatga
     5881 ccgacttaat aaattgacag aagctcataa agctctgaat ggtcaagaga aatttaagga
     5941 agaaaagaca gaacttgatc gcttaacagg tgaggttcaa gaactcttgg ctgccaaacc
     6001 aaaccatcct tcaggttctg ccctagctcc gcttcttgag aaaaacaagg ccttggttga
     6061 aaaagtagat ttgagtccag aagagcttgc aacagcgaaa cagagtctaa aagatctggt
     6121 tgctttattg aaagaagaca agccagcagt cttttctgat agtaaaacag gtgttgaagt
     6181 acacttctca aataaagaga agactgtcat caagggtttg aaagtagagc gtgttcaagc
     6241 aagtgctgaa gagaagaaat actttgctgg agaagatgct catgtctttg aaatagaagg
     6301 tttggatgaa aaaggtcaag atgttgatct ctcttacgct tctattgtga aaatcccaat
     6361 tgaaaaagat aagaaagtta agaaagtatt tttcttacct gaaggcaaag aggcagtaga
     6421 attggctttt gaacaaacgg atagtcatgt tatctttaca gcaccacact ttactcatta
     6481 tgcctttgtt tatgaatctg ctgaaaaacc acaacctgct aaaccagcac cacaaaacaa
     6541 agtccttcca aaacctactt atcaaccggc ttctgatcaa caaaaggctc ctaaattgga
     6601 agttcaagag gaaaaggttg cctttcatcg tcaagagcat gaaaatactg agatgctagt
     6661 tggggaacaa cgagtcatca tacagggacg agatggactg ttaagacatg tctttgaagt
     6721 tgatgaaaac ggtcagcgtc gtcttcgttc aacagaagtc atccaagaag cgattccaga
     6781 aattgttgaa attggaacaa aagtaaaaac agtaccagca gtagtagcta cacaggaaaa
     6841 accagctcaa aatacagcag ttaaatcaga agaagcaagc aaacaattgc caaatacagg
     6901 aacagctgat gctaatgaag ccctaatagc aggcttagcc agccttggtc ttgctagttt
     6961 agccttgacc ttgagacgga aaagagaaga taaagattaa atatcgaaaa atcttgtgaa
     7021 atctttcctt atatttccaa agtgtgatat aatagtttcg aataaaataa ataaaggagt
     7081 ttttgtaaca tggcaaaact tactgttaaa gacgttgact tgaaaggtaa aaaagtcctc
     7141 gttcgtgttg acttcaacgt accattgaaa gatggcgtaa tcactaacga taaccgtatc
     7201 acagcagctc ttccaactat taagtacatc atcgaacaag gtggacgtgc aattcttttc
     7261 tctcaccttg gacgtgtgaa agaagaagct gataaagctg gtaaatcact tgctcctgta
     7321 gcagcagact tggcagcaaa acttggtcaa gatgttgttt tcccaggtgt cactcgtggt
     7381 gctgaattgg aagcggcaat caacgctctt gaagatggac aagttctctt ggttgaaaac
     7441 actcgttacg aagatgttga cggcaagaaa gaatctaaaa acgatcctga acttggtaaa
     7501 tactgggcat cacttggaga tggtatcttc gtaaacgatg cattcggtac agctcaccgt
     7561 gcacacgcat ctaacgttgg tatctcagca aacgttgaaa aagcagttgc tggtttcctt
     7621 cttgaaaacg aaattgccta catccaagaa gcagttgaaa ctccagaacg tccattcgtg
     7681 gctatccttg gtggttcaaa agtttcagac aagatcggtg ttatcgaaaa cttgcttgaa
     7741 aaagctgata aagtccttat cggtggtggg atgacttaca cattctacaa agcacaaggt
     7801 atcgaaatcg gtaactcact tgtagaagaa gacaaattgg atgttgcgaa agctcttctt
     7861 gaaaaagcaa atggtaaatt gatcttgcca gttgactcaa aagaagctaa cgcatttgct
     7921 ggttacactg aagtgcgtga cactgaaggt gaagcagttt ctgaaggctt ccttggtctt
     7981 gacatcggtc caaaatctat cgccaaattt gacgaagctt tgactggtgc caaaacagtt
     8041 gtatggaacg gacctatggg tgtatttgaa aacccagatt tccaagctgg tacaatcggt
     8101 gtgatggacg ctatcgtgaa acaaccagga gttaaatcaa tcatcggtgg tggtgactca
     8161 gctgccgcag cgattaacct tggccgtgca gacaagttct catggattag tacgggtggt
     8221 ggagcatcaa tggaacttct tgaaggtaag gttcttccag gacttgcagc cttgacagaa
     8281 aaataagatt ttataaacaa atcaaagaag agagggatga aagttcctct tttcttttgc
     8341 ttaaaataaa aacgcttcct ctcaactatt actcataaaa atcaccgatt tatgataaaa
     8401 tggaaataga aagttgagat tatgagttat tttaaaaaat ataaattcga taaatcccag
     8461 ttcaaacttg gtatgcgaac ctttaaaaca ggtattgctg tttttctagt tctcttgatt
     8521 tttggctttt ttggctggaa aggtcttcaa attggtgctt tgacagccgt ttttagcctg
     8581 agggagagtt ttgatgagag tgttcatttt gggacttcgc gtattctagg aaatagtatc
     8641 ggtggactct atgccttggt cttcttctta ttaaatactt ttttccacga agccttttgg
     8701 gtgaccttgg tagttgttcc aatctgcacc atgttaacca ttatgacaaa tgtagccatg
     8761 aataacaaag caggggttat tggtggtgta gcagctatgt taatcattac cctatcaatt
     8821 ccaagtggcg agacaatttt gtacgtgttt gtgcgtgtat tagaaacgtt tatgggagtt
     8881 tttgtcgcaa ttatcgtaaa ttacgatatt gatcgtattc gtctcttttt agagaaaaaa
     8941 gaaaaataat gttacatttt ataacattat caattgacgt ttgtcttttt ttagactata
     9001 atagacagaa agaaggaaat tgtaaatgaa ggaaaaagaa tttcgccgaa atatggctgt
     9061 ttttcctatc ggcagtgtta tgaagttgac cgatctatcg gcgcgtcaga ttcgttatta
     9121 tgaagatcaa gagttgatca agcccgatcg aaacgaagga aatcgtcgca tgtattcctt
     9181 gaatgacatg gatcgtctgc ttgaaatcaa agattatatc tctgaaggtt ataatatcgc
     9241 tgccattaag aaaaaatatg ctgaacgtga agcgaaatcc aagaaagcgg ttagtcagac
     9301 tgaagtacgt cgtgcacttc acaatgaact cctccaacag gggcgttttg cttcagtaca
     9361 gtcacctttt ggtcgcggtt aggcaaccgc aagtagtcat agattaagga gaaaacttat
     9421 gccaatcaca gctgcagata ttcgtcgtga agtcaaggaa aaaaatgtta cctttattcg
     9481 tcttatgttc tcagatattt tgggaaccat gaaaaacgtc gaaattcctg ctacagatga
     9541 acagttagat aaggtcttgt cgaacaaggt tatgtttgat ggatcttcta ttgaaggttt
     9601 tgtacgtatc aatgagtcgg atatgtactt gtatccggac ttggatacat ggacagtctt
     9661 cccttgggga gatgaaaatg gaagtgttgc aggtctgatc tgtgatgtct atacaacaga
     9721 aggtgaacca tttgcgggtg accctcgtgg taatttgaaa cgagctcttc gtcacatgga
     9781 agaagttgga ttcaaatcct tcaaccttgg tccagagcca gaattcttcc tatttaagtt
     9841 ggatgaaaat ggggacccaa cacttgaagt gaatgacaag ggtggctact ttgatttggc
     9901 acctactgac cttgcggaca acacacgtcg tgagattgtg aatgtcttga ccaaaatggg
     9961 atttgaagta gaagcgagtc accacgaggt tgcggttgga cagcatgaga ttgactttaa
    10021 gtacgatgaa gttctccgtg cttgtgataa gattcaaatc tttaagcttg ttgttaaaac
    10081 cattgctcgc aaacacggac tttacgcaac atttatggcg aagccaaaat ttggtattgc
    10141 tggatcaggt atgcactgta atatgtcctt gtttgatgca gaaggaaata acgccttctt
    10201 tgatccaaat gatccaaaag gaatgcagtt gtcagaaaca gcttaccatt tcctaggcgg
    10261 tttgatcaag catgcttaca actatactgc catcatgaac ccaacagtta actcatacaa
    10321 acgtttggtt ccaggttatg aagcgcctgt ttacattgct tgggctggtc gtaaccgttc
    10381 gccacttgtg cgcgtacctg cttcacgtgg tatgggaact cgtcttgagt tgcgttcagt
    10441 ggatccaatg gcgaaccctt acgttgctat ggctgttctt ttggaagttg gtttgtatgg
    10501 tattgaaaat aaaatcgaag caccagctcc tatcgaagaa aatatctaca tcatgacagc
    10561 agaagagcgc aaggaagctg gtattacaga ccttccatca actcttcaca acgctttgaa
    10621 agctttgaca gaagatgaag tggttaaagc tgctctcgga gatcacatct atactagctt
    10681 ccttgaagcc aaacgaatcg aatgggcaag ttatgcaacc ttcgtttcac aatgggaaat
    10741 tgataattat ttagaccttt actaatacta atatagaaga aagattgcct gtgggtaaac
    10801 agtcacacag cagtctaagc catcaaatac ctataaccct taaaatagcg atttcggtcg
    10861 ctatttattt ttcgaaaaat cctcttgact cttttgcgaa ttagatttat catcagacgt
    10921 gtagaagaaa attaaggagt cactatggaa aaattcaatt tcaaaaacaa tatcgggcaa
    10981 gaaaacaagt tacttcaaat cgaaatctac aagtttacta acttttacaa gcttcaaaat
    11041 tacacatctg taaatatttt ttcgaaagat atatttgaag ccatagtaaa ttgagactag
    11101 aatagtacac tacatctgct aaaaatttct agaaactaat ttaactttcc taatcgattt
    11161 gtttacatct tatttcaatc tactatatta tctcaataaa tgatgatggc gactgttttg
    11221 tttgtgcttg tcgatttttg aatccctgat cgagcggaag aatatttctg ccgaggttgc
    11281 caaggggaaa atactgaaga tattgaattt tatgatgaac aattacaggc agaaaaggtg
    11341 gaggttttga atattcgatt ggaagtaaaa aattgaatta tctacaatct catcaacaat
    11401 aaacctattt caaccccatt atctataggc gtatttttac gcctttttat atacttgaag
    11461 cacataagaa acattatggg aagtttgctg atggaagtac tcaagaaatt gatgttcctt
    11521 atgatattcc tgatacttgg gagtgggtga ggataaaatc aatttattgg aattttgggc
    11581 aaaataagcc agagaaatcc tttaggtata tagatacgtc tagtattgat agaaaaaaga
    11641 acataatcaa ctacaaaaat ctacaatatc tttcacctga acaagcgcct tcccgtgcca
    11701 gaaaattagt ttcgcagaat agtgtcttat tttcaacagt tagaccatat ctaaaaaata
    11761 ttgctgtagt tagagaactt aaagagtatt tgatagctag tacagcattt attgttttgg
    11821 atactttact taacga
//
LOCUS       DAVKZI010000054        11808 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKZI010000054 DAVKZI010000000
VERSION     DAVKZI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.055"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            199..852
                     /locus_tag="VXB18_001882"
     CDS             199..852
                     /locus_tag="VXB18_001882"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0383034.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            862..1326
                     /locus_tag="VXB18_001883"
     CDS             862..1326
                     /locus_tag="VXB18_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0383035.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1339..2607
                     /locus_tag="VXB18_001884"
     CDS             1339..2607
                     /locus_tag="VXB18_001884"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0383036.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2621..2881
                     /locus_tag="VXB18_001885"
     CDS             2621..2881
                     /locus_tag="VXB18_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383037.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2892..4253
                     /gene="pdrM"
                     /locus_tag="VXB18_001886"
     CDS             2892..4253
                     /gene="pdrM"
                     /locus_tag="VXB18_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0383038.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKPKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4407..5375
                     /locus_tag="VXB18_001887"
     CDS             4407..5375
                     /locus_tag="VXB18_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0383039.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5391..6383
                     /locus_tag="VXB18_001888"
     CDS             5391..6383
                     /locus_tag="VXB18_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0383040.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6601..7644
                     /locus_tag="VXB18_001889"
     CDS             6601..7644
                     /locus_tag="VXB18_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0383041.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVITQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7708..9393
                     /gene="lpdA"
                     /locus_tag="VXB18_001890"
     CDS             7708..9393
                     /gene="lpdA"
                     /locus_tag="VXB18_001890"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0383042.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKGDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9457..10446
                     /locus_tag="VXB18_001891"
     CDS             9457..10446
                     /locus_tag="VXB18_001891"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0383043.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIKVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLTQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10519..11589)
                     /gene="xerS"
                     /locus_tag="VXB18_001892"
     CDS             complement(10519..11589)
                     /gene="xerS"
                     /locus_tag="VXB18_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0383044.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKIMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3509 a         2203 c         2660 g         3436 t
ORIGIN      
        1 gataatcttc gaaagaggta gtaaaatgct taatgattta aaaagtaatt ataaaaaata
       61 gccagtcttt ataaactgta ttcacgtatt caaatcgtat atatagtcga tttattaaat
      121 ctttagataa actgtaaaaa gtggtttcca tagccacttt ttgctataat agaggcagta
      181 aaaatgaagg agtcggctat ggaacactcg tcttggcatg ctttgattaa ggcgcaatta
      241 cctgagggtt atttcgggaa aatcaatcag tttatggagc aggtctattc tcaggggatt
      301 atttatccac ccaaggaaaa ggtttttcag gctctcttga caacactgct tgaagaagtt
      361 aaggtggtaa ttctagggca agacccctat cacggaccag gtcaagcgca gggcttgagt
      421 ttttctgtac ctgactctat cccagctcca ccatccttgc aaaatatctt gaaagaattg
      481 tcagatgata tcggagttaa gaaatctcat gatttgacag cttgggctga gcaaggagtc
      541 ttgcttctta atgcttgttt gactgttcct gctggacagg ccaatggtca tgctggtcaa
      601 atctgggagc cttttactga tgctgtgatt caggtggtca atcatctaga tagaccagtc
      661 gtttttgtac tctggggagc ttatgcacgt aagaagaagg cattagttac caatcctcat
      721 cacttgatta tcgaatcagc ccatccaagt cctttgtcgg tttatagagg attttggggt
      781 tccaagccct tttccaaggc caatgcattc ttaaaagaga caggacaaga gccaatcgat
      841 tggcttagat aaggagaaaa tatgcctcag ttagcgacga tttgctacat tgataatggg
      901 aaagaactgc tcatgctcca tcgtaataag aaacccaatg atgtccatga agggaaatgg
      961 attggtgtgg gtggtaagct agagagagga gagacgcccc aggaatgcgc ggcgcgtgaa
     1021 atccttgaag aaacagggct caaagccaag ccagttctaa aaggtgtcat cacttttcct
     1081 gaatttacac cagatttaga ctggtacacc tatgttttta aggtgacgga gtttgagggc
     1141 gacttgattg actgcaatga ggggacgcta gaatgggttc cctatgacga ggttttgagc
     1201 aagccgactt gggaaggtga ccacaccttt gttgagtggc ttttagagga taaacccttc
     1261 ttttcagcca agtttgttta tgatggggat aaattgttgg atacccaagt tgatttctat
     1321 gaataaagga gaaagcagat gctactaatc aaaaatggtc gtgtaatgga tcctaagtct
     1381 ggtttggatc aagtttgtga tgtcttagtt caagatggga aaattatcaa aattgcgcct
     1441 gagatcacgg aagaaggagc agaaacgatt gatgctactg gtcttgtggt tgctcctggt
     1501 ttggtcgata ttcatgtgca tttccgtgaa cctggtcaaa cacataaaga agacattcat
     1561 actggtgccc tggcagccgc tgcaggtggt tttactactg tcgtcatgat ggctaatacc
     1621 agtccaacca tttcagatgt ggagactttg caagcagttc tccagtcagc tgccaaagag
     1681 aagattaatg tcaagacagt tgcgaccatt actaaaaact ttaatggtaa aaacttgact
     1741 gactttaagg cgctcttaga agctggtgcg gttggtttct ctgatgacgg tattccgctt
     1801 gagagcagta agattgtcaa ggaagccatg gaggaagcca aaaaactcaa tacctttatc
     1861 agccttcatg aggaagatcc aggtttgaac ggtgttcttg gctttaatga aaatattgct
     1921 agagaacatt tccatatctg cggtgctact ggggtggctg agtacgctat gatggcgcgt
     1981 gatgtcatga ttgcctatgc aactaaagcc catgttcaca tccagcattt gtctaaggaa
     2041 gaaagtgtta aagtagtgga gtttgctcag gggttaggtg cagaagtcac agcagaagta
     2101 gcgccacagc atttctctaa gacagaagca cttcttttaa cacaaggtag caatgctaag
     2161 atgaatccac cgcttcgttt ggaatcagac cgtcgtgccg ttatcgaagg tctcaaatca
     2221 ggtgtcatca cagttattgc gactgaccac gcgcctcatc atgtagatga aaaaaatgtt
     2281 gaggatatta ccaaagcgcc atctggtatg actggcttag aaacatccct gtctctcggc
     2341 ttgacctatt tagtagaagc tggtgagttg agcttgatgg aattacttga aaaaatgaca
     2401 tacaacccag ccaagcttta caactttgaa gcaggttact tggctgagaa tggtccagca
     2461 gatatcacta tttttgatgc caaggctgac cgccttgtgg actcccattt tgcttccaaa
     2521 gcagctaatt caccattcat cggtgaaacc ttaaaagggc aggttaaata taccatctgt
     2581 aagggacaaa tcgtctatca agcttgatag gagttagaat atgaattatt ttcgaaaacg
     2641 tagggagagg caagcgaaat ctaatagtgg aatttactgt cccgcagcta atcgttccaa
     2701 aattcaatat gaaactaaag aaaaagctga ccatgcggtt caatatgata acggaggttt
     2761 agttagaagc tattattgtc gtacatgtgc gtgttggcat actacttcaa aatctaataa
     2821 acctccgcta agtttgaaaa actatggtct gaaactcttt ggtttagata aatcagaata
     2881 gaaagagaag tatgtataag acaaagtgtt tacgagagaa gttagtatta tttttaaaaa
     2941 ttttcttccc aatcctgatt taccaatttg ccaattattc tgcctctttt gttgatactg
     3001 caatgacagg tcaatacaac actatggact tggctggtgt atctatggca accagtatct
     3061 ggaatccttt ctttacattt ctaacaggga ttgtgtcagc cttggtgcct atcattggtc
     3121 accatcttgg tcgaggaaaa aaggaagaag ttgcgtctga tttttaccaa tttatttatt
     3181 tggccttggg cctatctgtg gtattgctgg ggatggtact tttcttggca ccaacaatct
     3241 tgaatcatat tgggttagaa gcagcagtag cggcagtagc ggttcgctat ctttggtttt
     3301 tatctatcgg gattatcccc ttgttgctct ttagcgtcat tcgttccttg ctggattcgc
     3361 tgggcttgac caaactgtcc atgtacctca tgcttttgtt actccctctc aatagcggat
     3421 ttaactatct cttgatttac ggtgcctttg gtgttccaga actgggaggg gctggtgctg
     3481 gtttaggaac atccttggcc tactgggtct tgcttgggat ttctgttctg gttttattta
     3541 aacaggagaa gcccaaagcc ttacaccttg agaaacgaat tccacttaat atggataaaa
     3601 ttaaggaagg agttcgttta ggtctgccta ttgggggaac tgtcttcgcg gaagtggcta
     3661 tcttttcagt ggttggcttg attatggcta agttttcgtc cttgattata gctagtcacc
     3721 agtcagctat gaacttttca agtcttatgt acgcctttcc tatgagtatc tcatcggcta
     3781 tggctattgt cgtttcctat gaagtgggag ccaagcgatt tgatgatgcg aaaacctata
     3841 ttggtctagg aagatggact gccctcattt ttgcggcctt caccttaacc ttcctttaca
     3901 tttttagggg aaatgtggcc agtctttatg gtaacgaccc aaaatttatc gatttgacag
     3961 tgcgtttttt aacttatagt cttttcttcc agttagcaga tacctttgcg gcgccgcttc
     4021 agggaatttt gcgggggtat aaggatacag ttattccttt ttaccttggt ttgcttggtt
     4081 attggggcgt agcaatccct gtggctacgc tatttgattc tctaacagat tttggagctt
     4141 attcttactg gatcggcttg attattagtt tgattgtgag tggggcgctc taccgttggc
     4201 gtttaactgt gattatgaag agatttgaat ctttagcaaa atccaaatgc taaaaagttt
     4261 gtgaaaaaat attcttgaca agaaaatccc ttgttttcac ggggttttct tttttatttt
     4321 gtgaaatttc ttttagaaaa actttgacag tatttgccaa aagcggtaaa atagtaaggt
     4381 aagaagaaag ttagaaaggc aagaagatgt caactttaga taaaaatctt ttgctagaaa
     4441 tgttccgtaa gatggaagaa atccgtcgca tggacttaaa aattgcacaa ttagtaaaga
     4501 aagggaaagt gccaggaatg acgcactttt ctgttggtga agaggcagct aacgtggggg
     4561 ctatgttagc tctcaatcca gatgatctga ttacctcaaa ccaccgtgga cacgggcaag
     4621 ctattgctaa agggattgac ctcaacggaa tgatggctga aatccttggt aaatacactg
     4681 gaacctgtaa agggaaaggt ggatctatgc atatcgctga ccttgatgct gggaaccttg
     4741 gtgccaatgg tattgtaggt ggtggtatgg ggatcgctgt cggtgcagcc ctcagtcagc
     4801 aaatgcaaaa taccggtaaa atcgttgtct gcttctttgg agatggtgcg accaatgaag
     4861 gtgttttcca cgaagcagtg aacatggctt ctatctggaa cctgccagtc attttctatt
     4921 gcattaacaa cggttacggt atctctgcgg atatcaagaa aatgaccaat atagaacata
     4981 tccatcaacg tagcgccgct tatggaattc ctggaatgtt catcgaagat ggtaacaatg
     5041 tcatcgatgt ctatgaagga tttcagaaag ctgtggacca tgttcgcagt ggcaatggtc
     5101 cagtcttgat tgaaagtgta acttatcgct ggctcggtca ctcatcatct gaccctggta
     5161 aatatcgtac gcgtgaagaa gtggaattgt ggaaacaaaa agatccaatc gaaaacctcc
     5221 gcaattacct tattgaaaat aacattgcaa gtgccgaaga attggaagaa atccaagcgc
     5281 aagtaaagga agcagtagaa gcttctgtta aatttgcaga ggaaagccca ttcccaccgc
     5341 ttgaatcagc ctttgaagat atttacgcag actaaggaga aagagataaa atggaaacaa
     5401 aaacaatgtc cttccgtgac accattatcc ttgctatgtc tgaggaaatg cgtcgcgatg
     5461 aaaatgtgtt cttgatggga gaagacgtcg gtgtcttcgg aggagacttc ggtacttctg
     5521 ttggaatgct tgaagaattt ggtccagaac gcgtccgtga ctgtccgatt tctgaagctg
     5581 ccatctctgg agcagcagca ggagcagcca tgacaggact tcgtccaatc gtcgatatga
     5641 ccttcatgga cttctctgtt attgccatgg acaatatcgt caaccaagct gctaaaacac
     5701 gttacatgtt tggtggtaaa ggtcaggttc caatgactgt tcgttgtgca gctggtaacg
     5761 gagttggctc tgccgcccag cactcacaat ctctagagtc ttggtttact cacattccag
     5821 gacttaaggt tgtggcacct ggaacacctg cggacatgaa aggcctgctt aagtcttcta
     5881 tccgtgataa aaacccagtt attatacttg agtacaagtc agaatttaac caaaaagggg
     5941 aagtgccagt tgatccagac tacacaattc cacttggggt tggtgaaatc aaacgccaag
     6001 gaacggatgt aacagttgtt acttatggaa aaatgcttcg ccgtgtggtt caagctgctg
     6061 aagaattagc agaagaagga atttcagttg aaattgttga cccacgtacc cttgttccgc
     6121 ttgataagga tatcatcata aactcagtga agaagactgg taaggttgtt ctggtcaacg
     6181 atgcccacaa aacaagtggc tatatcggtg aaatttcagc tattatttca gaatcagaag
     6241 catttgacta tctagatgca ccaattcgcc gttgtgcagg agaagatgtg ccgatgcctt
     6301 atgcacaaaa cctagaaaat gcaatgattc caacagttga aagtatcaaa gatgcaatcc
     6361 gaaaaactta taacaaagaa tagagttaca taagataagt tatgtaaata aaataaagct
     6421 gacgagaaac tttgtatctt ttaggtgcag agctcttcgt cattaatatc ttagattaga
     6481 gcacgggcta aaagctcgga aaaaagataa atctccttgg cttcatcgaa gccatcgtcg
     6541 atttcctatt tttcagtcgc ttttgacgcc ctttgtatca taaatagaat tggagaggtc
     6601 atggctgatg acaagctaag agcgactcct gcagctagaa agttagcgga tgatttaggg
     6661 ataaacctct acgacgtttc tggctcaggt gcaaacggtc gtgtccacaa agaagacgtg
     6721 gaaacttata aagacacaaa cgtggttcgc atttcgccac ttgcaaaacg aattgccctc
     6781 gaacataaca ttgcttggca ggaaatccaa ggaaccggtc atcgtggtaa aatcatgaag
     6841 aaggatgttt tggccctgct tcctgaaaat atcgaaaacg atagcatcaa atctcctgct
     6901 cagattgaaa aagtggaaga agtccctgat aacgtaacac catatggtga aatcgagcgt
     6961 attccaatga cacccatgcg taaggttatt acccaacgca tggttgaatc ttacttgact
     7021 gcgccaacct tcaccctaaa ctatgaagtt gatatgactg aaatgttggc tcttcgtaag
     7081 aaggttcttg agccaatcat ggaagcaact gggaagaaga ctactgtaac agaccttctt
     7141 tcacttgcag ttgttaagac tcttatgaaa cacccataca tcaacgcttc attgacagaa
     7201 gatggcaaga ctattatcac tcacaactat gtcaatcttg ccatggcagt tgggatggat
     7261 aatggattga tgacacctgt tgtttacaat gctgagaaga tgagtctttc agaactggtt
     7321 gtagccttta aggatgttat tggtcgtacc ttggatggta aattggctcc aagtgagtta
     7381 caaaattcaa cattcacaat cagtaatttg ggaatgtttg gtgttcagtc ctttggtccg
     7441 attattaacc aacccaactc agctatcctt ggtgtcagtt cgacaatcga gaagccagtt
     7501 gtcgtcaatg gtgaaattgt gattcgccca atcatgagtt taggattaac cattgaccac
     7561 cgtgtcgtag atggtatggc tggtgctaag tttatgaagg acttgaaaga gttgattgaa
     7621 acgccaatct caatgttaat ttaagagcaa gagtattcat ttttaagata tagataaagg
     7681 aaggaagaca tggccttaga agtaattatg ccaaaagccg gcgtggatat gacagaagga
     7741 caaatcgtcc aatggaataa aaaagtcgga gaatttgtaa aagaaggaga aatccttttg
     7801 gaaatcatga ctgataaagt cagcatggaa ttggaagccg aagaagatgg gtacttgatt
     7861 gccattctca aaggagatgg tgaaactgtc cctgtaacgg aagttatcgg ttaccttggt
     7921 gaagaaaggg aaaacatccc aacagctgga gcagcatcgc cagaagctag ccctgtacct
     7981 gtagcaagta cctcaaacga tgatggtaag agcgatgatg cttttgatat cgttgtgatt
     8041 ggtggaggtc ctgctggtta tgttgcagcc attaaagctg cccaactcgg cggtaaggtt
     8101 gcccttgttg agaaatctga acttggtgga acctgcttaa accgtggatg tattccaacc
     8161 aagacctacc ttcataacgc tgaaattatt gaaaatatcg gtcatgctgc aaatcgtggt
     8221 atcgtgattg aaaatcctaa cttcactgtt gatatggaaa aacttttaga aactaaatct
     8281 aaagttgtta atactcttgt tggtggtgtt gcaggacttc ttcgtagcta cggagttact
     8341 gttcataaag gaattggtac aatcactaaa gacaagaacg tcttggtaaa tggttctgaa
     8401 ttgcttgaaa ccaagaaaat cattcttgct ggtggttcaa aagtcagcaa gatcaacgtc
     8461 cctggtatgg aatctccact tgtcatgact agtgatgaca ttcttgaaat gaacgaagtg
     8521 ccagaaagcc ttgttatcat cggtggtgga gttgtcggta tcgaactcgg tcaggccttc
     8581 atgacgtttg gttcaaaagt gactgttatc gaaatgatgg accgtatagt tccagctatg
     8641 gatgcggaag tttctaagaa ccttcgcttg atccttgagc gtaaaggaat gaccatcttg
     8701 actggtacta aactgcaaga aatcattgag gaaaatggtc aacttcgtat caaggttgaa
     8761 ggaaaaggcg atatcatcgc aagcaaagct cttctttcaa ttggtcgtat gccagacctt
     8821 gaaggtattg gagaggttga gtttgaattg gatcgtggtt gtatcaaggt caatgaatac
     8881 atggaaactt cagttccagg catttatgca ccaggtgaca tcaacggtac taagatgttg
     8941 gctcacgcag ctttccgcat gggtgaagtt tccgctgaaa atgcccttaa aggaaatcat
     9001 gcagttgcca aattgaattt gactcctgca gccatctaca ctctccctga agtagcagca
     9061 gtaggtttga cagaagaaca agcccgtgag aaatacgatg ttgccatcgg taagtttaac
     9121 tttgctgcta acggtcgtgc tattgcatct gacgcagctc aaggtttcgt aaaagttatc
     9181 gctgataaga aatacggaga aatccttggt gtacacatta ttggtcctgc agccgcagaa
     9241 ttaataaacg aagcatcaag catcatcgaa atggaaatca ctgttgagga aatgctgaag
     9301 accatccacg ggcacccaac ttactctgaa gtgatgtacg aagcgtttgc agatgttcta
     9361 ggaatggcca tccattcacc taagaaaaaa taaaacgaag atagattaga ctggaaggtt
     9421 atttccagtt tctatcatat aaagtaaagg gatatcatga aatacattat caatcattca
     9481 aatgacactg cttttaatat tgccttggaa gaatacgcct ttaaacacct tttggatgag
     9541 gatcaaatct tcctactttg gattaacaag ccatctatca ttgttggtcg tcaccagaac
     9601 actatcgaag aaatcaaccg tgattatgtt cgcgaaaatg gtattaaggt agttcgccgt
     9661 attagtggtg gtggagctgt ttaccacgat ttaaataacc tcaactacac gatcatctcc
     9721 aaagaagatg aaaataaggc atttgacttc aagagcttct caactccggt tatcaatacc
     9781 ctgactcaac ttggggttaa agctgagttc acaggtcgta atgaccttga gattgatggt
     9841 aagaagttct gtggcaatgc ccaagcctat atcaacggcc gtatcatgca ccacggttgc
     9901 ttgctctttg acgttgattt gtcagtcctc gcaaatgccc ttaaggtttc aaaagataaa
     9961 tttgaatcaa aaggtgtgaa atccgtccgt gcccgtgtaa ctaatattat caatgaatta
    10021 ccaaaaaaaa tcacagtcga aaaattccgt gatttactct tggaatacat gaaaaaagag
    10081 tacccagaga tgactgaata cgtcttttca gaagaagaat tggccgaaat caatcacatc
    10141 aaggatacta agtttggaac ttgggactgg aactatggta aatcacctga atttaacgtc
    10201 cgtcgtggaa ccaaattcac tagtggtaag gttgaagtct ttgctaacgt tactgaatca
    10261 aaaatccaag acatcaagat ttatggtgac ttctttggta ttgaagacgt tgctgcagta
    10321 gaagatgtcc ttcgtggggt gaaatacgaa cgcgaagatg ttcttaaggc gctaaaaacc
    10381 attgatatca cacgctactt cgctggtatt agccgtgaag aaatcgctga agcggtagtt
    10441 ggataaatca aaaagaagtt ggccaactaa ccaacttctt tttttgatat ttatttacat
    10501 aatttaaaat acgtaaaatc ataaactatc tagagcattc ttttgttcat cattaacaat
    10561 atgggtatag aggtcggtga cttgtgtgct ggcatgtcct agttggtgac tgactaaaac
    10621 ttgtgattta gtcgcatcat agagcctagt tgctagtgta tggcgcagtt tatggggtgt
    10681 tacacgcact ttaaaatcct ctgagtattt agcaaccatt ttctcaacgc tagaagcatc
    10741 gatacgatta ggaacacctc tgtagagagt taaaaaaagg gctgtatctg ttttttccgt
    10801 tttatagcgt tgattccgaa tggccagata attctctaaa taaggtttag caaaagcagc
    10861 gacattgact gagtcacgtt tgccaccttt tcgagtaaca tcaataacca ttatttttag
    10921 attgagatct cttagatcta gattaacagc ttcagataag cgaacaccag atgccaagag
    10981 aagggcaata atggctaaat ctcgttcttt atttttgttg aatgatgaga gagctcgatt
    11041 tgaaagctgt tgtgggtgct cttgatcgat ataagttaga aaaccttctg tttcatcacc
    11101 tagaaagagt ttttgcttga tattttcagc tctggcagca agggtttctt tctttttctt
    11161 ggttgaaact tttttcatta cattacgata gaaataaggt tccccctgat cgttttcaac
    11221 ctcctcggtt agatacttgt aaagactaga aagtgctgat aaggttcgat tgatagttgt
    11281 ctgtgaaaca ccttgttttg ttgtattagc attcagcaag ggacgttcac gtagataaag
    11341 gataaaggat tccatgtctt tcttagacat attttccaaa actgataaag gaatatcgga
    11401 tattttatca gcgtttgaaa taccagactc caaaacccag ctgaaaaatc ggtcatattc
    11461 cttaaggtat tcgtacaggg ttgtaaaact gtagggcaca gccagcttag attggtagta
    11521 ttccagaaca taccagggca tgagttgttt tagtttgtcg attcgttcca gtaaaatctc
    11581 acgtttcatg tattttctcc ataagtaagt atactagtag tatagcatag acttgtatat
    11641 ttttcaagaa aattatagtt tttcagaaag atgttatagg agtttttcaa agtgataaaa
    11701 agacttagac ctacaaacaa aacagaataa ggaaaatctc acccactaaa cttctgttaa
    11761 tactacataa ctgaagagct atataaggag ctatgagata caaaacac
//
LOCUS       DAVKZI010000055        11614 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKZI010000055 DAVKZI010000000
VERSION     DAVKZI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.056"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VXB18_001893"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VXB18_001893"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0383045.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="VXB18_001894"
     CDS             complement(1169..1693)
                     /locus_tag="VXB18_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0383046.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /locus_tag="VXB18_001895"
     CDS             complement(1746..1982)
                     /locus_tag="VXB18_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0383047.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2050..2970)
                     /locus_tag="VXB18_001896"
     CDS             complement(2050..2970)
                     /locus_tag="VXB18_001896"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0383048.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEIYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3160..3564
                     /locus_tag="VXB18_001897"
     CDS             3160..3564
                     /locus_tag="VXB18_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383049.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLMIKHLKVKQ"
     gene            3780..4361
                     /locus_tag="VXB18_001898"
     CDS             3780..4361
                     /locus_tag="VXB18_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0383050.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="VXB18_001899"
     CDS             4358..5635
                     /locus_tag="VXB18_001899"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0383051.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLEDGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="VXB18_001900"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="VXB18_001900"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0383052.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDISAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="VXB18_001901"
     CDS             6302..6691
                     /locus_tag="VXB18_001901"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0383053.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6782..7834
                     /locus_tag="VXB18_001902"
     CDS             6782..7834
                     /locus_tag="VXB18_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0383054.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7978..9513
                     /locus_tag="VXB18_001903"
     CDS             7978..9513
                     /locus_tag="VXB18_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383055.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SIGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            9506..10564
                     /locus_tag="VXB18_001904"
     CDS             9506..10564
                     /locus_tag="VXB18_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0383056.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10567..11523
                     /locus_tag="VXB18_001905"
     CDS             10567..11523
                     /locus_tag="VXB18_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0383057.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3305 a         2071 c         2662 g         3576 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgaccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgcgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agctgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat
     2161 actgatccag acctgatggg caaaggactc tacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc taggctcagc attttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ccactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttgattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctc ttcgggtacg atgtcgtaaa tttcatgaga
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtttttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatataa
     3061 tataagtgat caatttattg atgaaatagg aggtagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttatagg aggtgtacta tgaaaatctt aaaacgttac
     3181 atattggaac tctgttttat tttaagtttt gctttacctt ttataaaagg agccaatgca
     3241 gataatggta tatgctttgt ggaaacctat tacggtttta cttttttgat ggaacatgct
     3301 attgtaacag ctgtctttat ctattcgttt ttaattgctt tcttactaaa aaaacgatgg
     3361 gcgaaatgga ttgctgctgg tagttattgc tttttagtcc tatggattgc gacagagggt
     3421 tatttcttcc gcatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aatattttgt taggaatttt gttgatgatt
     3541 aagcatttga aggttaagca atagtaatca aaatgcgcct gatgatagac aataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact cgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtattatgc agaaaatcct gacgctgctc acgacattca tgagttgaga gtagagttgt
     3841 tgggacaaaa aatgaccttt ttgacggatg cgggtgtttt tagcaagaaa atagttgact
     3901 ttggaagtca actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg
     3961 taggctgtgg ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga
     4021 ccatggttga tattaacact cgtgccctgg atttagctca gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgatattt caatctaata tttatgcaag agttcaaggg cgatttgacc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcatcgaga
     4201 aaagtaaaga tttcttggaa actggtgggg atttgacaat cgtcatccag aaaaaacaag
     4261 gggctccaag tgctaagtcc aagatggagg atgtgtttgg taattgtgaa atccttaaaa
     4321 aagacaaggg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaataca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctgg tagaaggcta
     4441 tgtgtcagga actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa
     4501 aggaatgacg actcgtgaaa tttctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattc tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattaa
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acagtagcag tgattacgga tatgagccag cctttgggac gagcgattgg
     5101 aaatcgtctg gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggc ttggcaaatg ttaacaagac
     5221 tgttgaagaa gttcgccaac atcttgagga tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgcct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatggctt tgccagtgtt
     5761 tgcgttaatc caacctgggt tgaacatgct aaaaaagggc ttgaaggcac agatgttaag
     5821 gtttgcacgg tagtaggttt ccctttggga gcaacaactt cagccgtgaa agcatttgag
     5881 acaaaagaag ctatccaaaa tggtgcagat gagattgata tggtgatcaa tgttggagct
     5941 ctcaaatcag gtaatttagc cttggttgag tcagatatta gcgcagtagt ggaagcaagt
     6001 ggtgataagt tagtgaaagt cattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 gttgtttgcc aattggccca aaaagctggg gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt acattaatgc gtgaaacagt tggatctgat
     6181 atgggagtca aggctgctgg tggagctcgt tcttatgcag atgctcttgc ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagccaaa gacggaaatg tttacacggg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagctatttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatt tcaccatgtg gtgcttgtcg ccaagtaatg gtcgaatttt ttgaacaaga
     6601 tttaaaagtg accttagtcg caaaagataa atcgacggtc gagatgacgg tcggggagtt
     6661 acttccatat tcttttacag acttaaatta gtctgagtcg ctctttgagt ggcaagggtc
     6721 tttgtgacca atcaatccat acttgcaaca tcgttgcaca tcttatttag gaggttcagt
     6781 aatgaacaag aaacaatggc taggtcttgg cctagttgca gtggcagcag ttggacttgc
     6841 tgcatgtggt aaccgctctt ctcgtaacgc agcttcatct tctgatgtga agacaaaagc
     6901 agcaatcgtc actgatactg gtggtgttga tgacaaatca ttcaaccaat cagcttggga
     6961 aggtttgcag gcttggggta aagaacacaa tctttcaaaa gataacggtt tcacttactt
     7021 ccaatcaaca agtgaagctg actacgctaa caacttgcaa caagcggctg gaagttacaa
     7081 cctaatcttt ggtgttggtt ttgcccttca caatgcagtt gaagaagcag ctaaagaaca
     7141 cactgacttg aactatgtct tgattgatga tgtgattaaa gaccaaaaga atgttgcgag
     7201 cgtaactttc gctgataatg agtcaggtta ccttgcaggt gtggctgcag caaaaacaac
     7261 taagacaaaa caagttggtt ttgtaggtgg tatcgaatct gaagttatct ctcgttttga
     7321 agcaggattc aaggctggtg ttgcgtcagt agacccatct atcaaagtcc aagttgacta
     7381 cgctggttca tttggtgatg cggctaaagg taaaacaatt gcagccgcac aatacgcagc
     7441 cggtgcagat attgtttacc aagtagctgg tggtacaggt gcaggtgtct ttgcagaggc
     7501 aaaatctctc aacgaaagcc gtcctgaaaa tgaaaaagtt tgggttatcg gtgttgaccg
     7561 tgaccaagaa gcagaaggta aatacacttc taaagatggc aaagaatcaa actttgttct
     7621 tgtatctact ttgaaacaag ttggtacaac tgtaaaagat atttctaaca aggcagaaaa
     7681 aggagaattc cctggcggtc aagtgatcgt ttactcattg aaggataaag gggttgactt
     7741 ggcagtaaca aacctttcag aagaaggtaa aaaagctgtc gaagatgcaa aagctaaaat
     7801 ccttgatgga agcgtaaaag ttcctgaaaa ataatggatg gaagtcattt cttaggaagc
     7861 ggccaagggc cgctttttta agagttgaga caaagtcatt ttgtctcagt aaagcttgct
     7921 actagacaaa ctagcaagtt ttattgaaat aaaataagac tctgaaagga agagcacatg
     7981 gcacacgaaa atgtcattga gatgcgtgat attaccaagg tgtttggtgg atttgttgcc
     8041 aacgacaaaa tcaacttgca cctacgaaaa ggtgaaattc atgcactttt aggagaaaat
     8101 ggggctggta agtccacgct aatgaacatg ttagcaggcc ttcttgaacc aactagtggt
     8161 gaaatcgcgg tcaacggtca agttgtcaat ctcgactccc catctaaagc agctagcttg
     8221 ggaatcggga tggttcacca gcactttatg ttggttgaag ccttcacagt ggctgaaaac
     8281 atcattttag gtagtgaatt gactaaaaat ggtgtgctag atatcgctgg agctagcaaa
     8341 gaaatcaagg ctctttctga acgttatggc ttagctgttg acccttctgc caaggtagca
     8401 gatatctcag ttggagccca acaacgtgta gaaattttaa aaacacttta taggggggct
     8461 gatatcctta tctttgacga accaacggct gttttgactc catcagaaat tgatgagttg
     8521 atggctatta tgaaaaatct tgtcaaagaa ggaaaatcaa ttatcttgat tacccacaaa
     8581 ttggatgaaa ttcgcgcagt ttctgaccgt gttacagtta tccgtcgtgg gaaatcaatt
     8641 gaaaccgttg aaattgcagg ggctaccaat gctgatttgg cggaaatgat ggtaggacgt
     8701 tctgtttcct ttaaaacaga gaagcaagcc tctaaaccaa aagaagtggt tttgtctatc
     8761 aaagatttgg tggtcaatga aaaccgtggt gttccagctg ttaaaaatct gtccttggat
     8821 gttcgtgctg gagagattgt tggtattgcg gggattgatg gaaatggtca gtctgaactg
     8881 attcaagcca ttacaggtct tcgtaaggtt gaatctggta gcattgagct aaaaggagat
     8941 tcaattgtag gcttgcaccc acgtcagatt acagaactaa gtattgggca cgttccagaa
     9001 gaccgtcacc gtgatggctt gattttggaa atgatgatat ctgaaaatat tgcccttcaa
     9061 acctactata aagaaccaca tagtaaaaat ggaattttga attattcaaa tattacttct
     9121 tatgctaaaa agctgatgga agagtttgat gttcgcgctg ccagtgaatt agttcctgca
     9181 gctgcactct caggaggaaa tcaacaaaaa gcaattattg ctcgtgaaat tgatcgagat
     9241 cctgatctcc ttatcgttag ccagccaact cgtgggttgg atgtcggtgc cattgagtat
     9301 atccacaaac gcttgattga agagcgtgat aatggcaagg ctgtccttgt tgtcagcttt
     9361 gaattggatg agattttaaa cgtctcagac cgtattgccg ttatccacga tggtaagatt
     9421 caaggtattg tatcaccaga aacaaccaat aaacaagaac ttggtgtctt gatggctggt
     9481 ggaaacttgg gaaaggagaa gagtgatgtc taaaaaatta caacaaattt cggttccctt
     9541 gatttctgta tttctaggaa ttttactcgg agccattgtc atgtggatct tcggttatga
     9601 tgctatttgg ggctacgaag aattgttcta tacagccttt ggcagtctgc gtgggattgg
     9661 agaaatcttc cgtgctatgg gtcctctggt cttgattggt cttggttttg cggttgccag
     9721 tcgagctggt ttctttaacg tcggacttcc tggtcaggct ttggcaggtt ggattctcag
     9781 tggttggttt gccctgtcgc atccagatat gccccgtccc ttgatgattc tagcaaccat
     9841 cgtgattgcc ttgattgctg gtgggattgt cggagcgatt ccaggtattc ttagggccta
     9901 tctagggacg tcagaggtta ttgtaaccat catgatgaac tacattgtct tgtatgtagg
     9961 gaatgccttt atccatgctt tccctaaaga cttcatgcaa agtacagatt cgaccattcg
    10021 tgttggggct aatgcaacct atcagacacc ttggttggct gagttgactg gtaactcacg
    10081 gatgaatatt ggtattttct ttgccatcat tgccgttgca gttatttggt tcatgctcaa
    10141 gaaaacaact cttggttttg aaatccgtgc agttggtctt aatccacatg cttcagaata
    10201 tgctggtatt tctgccaagc ggactattat cctatctatg attatttcag gtgccttggc
    10261 aggtcttggt ggagctgttg aaggtttggg aaccttccag aacgtctatg ttcaaggttc
    10321 gtcattagct atcggattta acggaatggc ggttagtttg cttgcggcca actcaccaat
    10381 tggtatactt tttgcagcct tcctatttgg cgttctccaa gttggggctc ctggtatgaa
    10441 tgcggcgcag gtaccatctg agcttgtcag cattgtaaca gcgtctatta tcttctttgt
    10501 cagtgttcat taccttatcg aacgctttgt caaaccgaaa aaacaagtta aaggaggtaa
    10561 gtaaagatgt ctattataac cttgctcccc ctcttggtgt cttctatgct gatttactca
    10621 gcacctctca tctttacaag tatcggtggt gttttctctg aacgtggtgg tgtggtaaac
    10681 gttggccttg aaggaattat ggttatgggt gccttttctg gagttgtctt taaccttgaa
    10741 tttgcagaac aatttggagc agcaactcca tggctatcct tgcttgtagc aggattggtt
    10801 ggtagtgttt tctctatcat ccacgcagca gcgacggttc atttccgtgc agaccatgtt
    10861 gtcagcggta cggtattgaa cttgatggcg cctgccttgg ctgttttctt agttaaagtt
    10921 ctttataaca aaggacaaac cgacaaccta agtcaaactt ttggacgctt tgatttccca
    10981 gtcttggcaa atatcccagt gattggtgat atcttcttca agtcaactag tctacttggt
    11041 tatctggcga ttgccttctc attccttgct tggtttattc tctttaagac tcaatttggt
    11101 cttcgtctcc gctctgtcgg tgaacatcct caagcagcgg ataccttggg aatcaacgtc
    11161 tacaagatga gatatttagg gattattatt tcaggttttc taggtggaat tggcggagcg
    11221 atttatgcgc aatcaatctc agttaacttc tcagtgacaa ctattgttgg acctggattt
    11281 atcgcccttg ctgcgatgat ctttgggaaa tggaatccaa tcggtgctat gctttctagt
    11341 ctcttctttg gactttcaca aagtttggct gttatcggtt ctcaattgcc gttcctacaa
    11401 ggagtgccag cggtttatct tcaaattgca ccttatgttt tgacaattct tgtcttagca
    11461 gccttctttg gaaaagcagt cgcaccaaaa gcagatggta tcaactacat caaatcaaaa
    11521 taagcataca aaaaaacgtc agtccaatga ctgaactacc ccccaaaagt tagacagaaa
    11581 aaatctaact tttggggtgt ttttattatg aaac
//
LOCUS       DAVKZI010000056        11365 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKZI010000056 DAVKZI010000000
VERSION     DAVKZI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.057"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(402..500)
                     /locus_tag="VXB18_001906"
                     /pseudo
     CDS             complement(402..500)
                     /locus_tag="VXB18_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(526..1158)
                     /locus_tag="VXB18_001907"
     CDS             complement(526..1158)
                     /locus_tag="VXB18_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0383058.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLVPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(1180..2052)
                     /gene="sdaAA"
                     /locus_tag="VXB18_001908"
     CDS             complement(1180..2052)
                     /gene="sdaAA"
                     /locus_tag="VXB18_001908"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0383059.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(2061..2732)
                     /gene="sdaAB"
                     /locus_tag="VXB18_001909"
     CDS             complement(2061..2732)
                     /gene="sdaAB"
                     /locus_tag="VXB18_001909"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0383060.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2974..3561
                     /locus_tag="VXB18_001910"
     CDS             2974..3561
                     /locus_tag="VXB18_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0383061.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3613..3933)
                     /locus_tag="VXB18_001911"
     CDS             complement(3613..3933)
                     /locus_tag="VXB18_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0383062.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            4359..4646
                     /locus_tag="VXB18_001912"
     CDS             4359..4646
                     /locus_tag="VXB18_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0383063.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            4698..6806
                     /locus_tag="VXB18_001913"
     CDS             4698..6806
                     /locus_tag="VXB18_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0383064.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTIPSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLSDVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSLFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHALLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            6803..7444
                     /locus_tag="VXB18_001914"
     CDS             6803..7444
                     /locus_tag="VXB18_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383065.1"
                     /translation="MIELDNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSTKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            7662..8459
                     /locus_tag="VXB18_001915"
     CDS             7662..8459
                     /locus_tag="VXB18_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0383066.1"
                     /translation="MKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVALNPD
                     FAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKADLAI
                     SGVSKTDERSKVFDFSIPYYTAKNKLIVKESDLTTYQSVNDLAQKKVGAQKGSIQETM
                     AKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNFEKE
                     QDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            8425..8895
                     /locus_tag="VXB18_001916"
     CDS             8425..8895
                     /locus_tag="VXB18_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0383067.1"
                     /translation="MRMPLKRPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVAVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQIEYQIAVAKKANEAKK"
     gene            complement(9185..10048)
                     /locus_tag="VXB18_001917"
     CDS             complement(9185..10048)
                     /locus_tag="VXB18_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0383068.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGARELSDHTEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            10514..10852
                     /locus_tag="VXB18_001918"
     CDS             10514..10852
                     /locus_tag="VXB18_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0383069.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            10830..11201
                     /locus_tag="VXB18_001919"
     CDS             10830..11201
                     /locus_tag="VXB18_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0383070.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
BASE COUNT         3456 a         1938 c         2444 g         3527 t
ORIGIN      
        1 ttctttgtgt gaatccctat tgacgacatc tataatttgg atatttgtgt ctttgatatc
       61 gagtagtttt gtgataaaat gtaattgtcc catatgaatc tttctaatga gttgtttgat
      121 cgcttttcat tatagatctt atgggacttt ttttctacaa taaaataggc tccataatat
      181 ctatagtgga tttacccact acaaatatta tagagccgaa taaaaaagaa aaacgcatat
      241 tatcaagtta aataaccttg gtaatatgcg ttttattatg tagagactta tactcttcga
      301 aaatctcttc aaatcacgtc aacgtcgcct tgccgtatat ggttactgac ttcgtcagtt
      361 ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttccatc cacaacctta
      421 aaacagtgtt ttgagcagcc cgcagctagt ttcctagttt gctctttgat tttcattgag
      481 tattacttca ttttcttctg aaatggaatt gttacccagt ctatgctatt gaaaatacgc
      541 caaaacctct aagggtttgt gagcgatata atcaggttga tagtttagta gatctgcttg
      601 ctctccaaat ccccaagtga tggccaattt ctgaatacct gtttctcgag ctcccagcat
      661 atcaaacttg gtatctccga tgatgatggc ttgttctggt actagttgat gtgtctgcaa
      721 ggcttggtga atgacatctg ccttatgggg tgcttcaggg ctagaaccat aaatgccatc
      781 aaagaaatga tggatttcca agttttttgc catgtcttga gcagtagatg tattctttgt
      841 cgtggtgatg tagagtggat aactgctcga taactcctca agcaagtcta taatctgagg
      901 aaagagttga gcttcataga tgccttttgc cttatagtaa gaacgatata tctgcacggc
      961 ttcagaaatt tggtctttgg acaggcaggt cgcaaaacta ctttcgagag gtggtcccat
     1021 aaaaccacga atagttttgg catcagggct aggcaccccc agctctttaa aggtataggt
     1081 aaaggcattg tgaatcccga tagaactatc aacgagggtt ccatccaaat cgaaaaaaat
     1141 cgctgtgata gaggtcatgg tttctcctat ttgataagct tattctccga aaatttcttt
     1201 ttggaggcga cgaccagtag gggtggtagc gagtccacct tcagctgttt cacgaaaggc
     1261 agttggcatg cttgctccta cttggtacat ggcatcgatc acttcatcca cagggatttt
     1321 agattcgata cctgccaagg ccatgtctgc tgcgatgaaa gcaaagctag ctcccatggc
     1381 attacgtttg acacagggaa cttcgaccaa acctgcaaca gggtcacaga tgaggcctag
     1441 catattttta atgacaaagg caatagcttg actggcctga taaggtgttc cacctgcagc
     1501 cagagtcaag gcggcagcac tcatagcaga ggctgaacca acttcagctt gacacccacc
     1561 ctcagcacct gagatggagg cattgtttgc gatgactagt ccaaaggcac cagcagcaaa
     1621 gaggaaatcc aattgttgct cgtggctgag gtctaatttt tcaatagcag cagtgagaac
     1681 ggaagggaga caaccggcac ttcctgcggt aggagtagcg cagaccaagc ccattttagc
     1741 attgtgttca ttgactgcga tagcatttcg ggcagcagag agaatcgtat aatctgacag
     1801 agtttttccg ttttcgatgt agtgatccaa tttggcagca tctccacctg tcaggccact
     1861 acgagattta ttttcattga ggccaagttg gacagaggct ttcataactt ccagattgcg
     1921 ttccatgaga aggaagactt cttcacgttc gcgaccggtc aattcaaact ctgttgtaat
     1981 catgagttct gcgacatttc cttgaaagtc cagatctgct tgctcgacca attctttgat
     2041 agaataaaac atgcttcctc ctatttaaag aaattgacat tgtggagatg agggattttt
     2101 cgaatttctt cgatagcctc atcacagttg cgactgtcaa cttcgataat cataatggct
     2161 ttttcaccag ctttttcacg agtgacattc atctgggcga tattgatacc atagcgggaa
     2221 agcgcctctg taacaagggc aatcatacct ggaatatctt gatgaacgat gatgatagtc
     2281 ggtgtattca tattgagaga gacggcaaaa ccattgagtt cggttacctg aatatttcct
     2341 ccaccgatag aaataccagt cacgctgatg gtcttgtggg catttttaac agtaatttta
     2401 gtggtgttag ggtgaggggc attgctgtct ttctgaatgg tccagacaat cttgatacca
     2461 cgcttgtggg caatttccag actatttgga atttcaggat catctgtatc cattcccaaa
     2521 atacctgcaa caagggctag gtctgttccg tgaccacgat aggtcttggc aaatgagtta
     2581 aaaagttgga attcaacttc tgtcggagta tcatcaaaaa tggaagagac aatcttccca
     2641 atacgaacag caccagcggt atggctacta gatgggccaa tcataactgg tccgatgata
     2701 tcaaagacag attgaaaacg aagtgatttc atcagtttcc ccttataaaa attcttatct
     2761 ctattatatc aaagaatgag gggcttggct ttaattgtgg atgaaaacct ttctaatacc
     2821 tcaaatagca taaaaatagt atcttttatg acaaaaaaca ccttatttag ggaaataaaa
     2881 aataattttg taatatttct acataaaagt gtcaagaaac ggtaatattt aaagggtatg
     2941 atagaactat agaaagaagg agaattttcg aatatgaaat caataactaa aaagattaaa
     3001 gcaactcttg caggagtagc tgccttgttt gcagtatttg ctccatcatt tgtatctgct
     3061 caagaatcat caacttacac tgttaaagaa ggtgatacac tttcagaaat cgctgaaact
     3121 cacaacacaa cagttgaaaa attggcagaa aacaaccaca ttgataacat tcatttgatt
     3181 tatgttggtc aagagttggt tatcgatggc cctgtagcgc ctgttgcaac accagcgcca
     3241 gctacttatg cggcaccagc cgctcaagat gaaactgttt cagctccagt ggcagaaact
     3301 ccagtagtaa gtgaaacagt tgtttcaact gtaagcggat ctgaagcaga agccaaagaa
     3361 tggatcgctc aaaaagaatc aggtggtagc tatacagcta caaatggacg ttatatcgga
     3421 cgttaccaat taacagattc atacctgaac ggtgactact cagctgaaaa ccaagaacgt
     3481 gtagcagatg cctacgttgc aggacgttac ggttcatgga cagctgctaa aaacttctgg
     3541 cttaacaatg gctggtatta agaactaacg aacaaataat atgtaaagag tcgaggaaat
     3601 ccctcggctt ttttatcttt ccttcgcttg gtaatagatc tctacttctt ttttgagatg
     3661 agacagcata gaagtttcct cggttagctc taggagtgag aaaccttttt ggataagttt
     3721 cgcatcatcc ctacaaatcc caatagggac atagcagata gccagcctat cgtagctttt
     3781 cttattcttg gcgtcctcca gtaaagtgta gcagatttgc ttacacatgt ttttatcttg
     3841 attgtataga tagagtgtgg aaaggttgag caggattgct attcgcaagt catataaatg
     3901 ttgatagttt ttatagactt ctaagcgttg caagattttc tcggattatt gacaaataaa
     3961 cggacattct gatagacgat tgccctagcg gcttagtgta aactttacaa atttggcttg
     4021 taattttttt tataaaattc acttcagtta cttgacagtt attatatttt cacttattat
     4081 atagataaaa ggatgggata ggagtttaaa aatttgaaag cgctatccat attgtttatt
     4141 ggactgattc ttgagtaata gttagagtgt gcttaatact actctggttg ttcaaggacc
     4201 tgatacagaa gcgcaccatt ctcccggtta agagtaagtt cgttgttaaa aaatgaaatg
     4261 agatagaagg aaggtgagtc caatggacta cgatacttgt tgataaatta ctatagctgt
     4321 ttttacggaa cagctctcga taataggaga aataaatcat gagaaaatta gttaaaattg
     4381 gtgttgcatc tttaatggta tgtggtatac ttgctactac aaatgcttta gcagtatggg
     4441 ttgagggtgg tcaatggaac tatggagtag gttggacagg aacttttgga tattctgatt
     4501 acttacattc tactcgatat catacagcaa ctgttagaca tgggggtaga acctctaagg
     4561 attatgcaaa acctgaggca tgggctagag cttccctcac caagattccg ccaacaggaa
     4621 tggaatattt ctatggattt gagtaaaatt cttccctctc ctatttggag agggaaaact
     4681 gtagtggagg cacttttatg aaaaaaatca gtaatttctg tatgttactc ctgcttctgt
     4741 gtaccacttt ttttgttttt aatgtaaact atacacgaga agtggttcgg attcaagaaa
     4801 tgggaaagac tgtagattct ttggatttgt atttgaaaga tattaacgaa cctgcagcgt
     4861 ctgttcttcg attttttgag gatgtatcaa aggagtataa agtctccatc atcaaaacag
     4921 acagtggtga tgaggtggtc aagtctggtg tttttgataa agataccttc ccctaccaag
     4981 agtttgggat ttcttctctt gattttacca cagatggtga aggagtctat agtaataaag
     5041 aaatttccaa taaacttggt acgattccga cctttctaaa agccaaacct attcagctta
     5101 tgacttttca aacctatatc aaggatacat ctcgtagttt aaatggtcgc tatacgatac
     5161 cttctacaca agagatggac aaggatagga ttgtacagaa atggagcgat tttttcaaga
     5221 tagaccaggc taccttgcta gagccgacct acaaaagtgc agtggaagtc ataaatcgag
     5281 atttgctttt atctgccatt gtttttgtct tggctatttt gcttcttgtg ttagtgacag
     5341 tgtatcaacc gatgatggag atgaaacgag ttggggtaca aaaattactt ggttttcaag
     5401 atagggctgt tttatctgat gttgtaaaag gcaaccttta cctcctccta ggtggggctc
     5461 ttgtgatcaa tctaggcgtg tttttcttgc ttgattataa gccaaaagat ttgtttccta
     5521 tgctgtggtt gtctcttttt ttgctgttgc agctttatct ctttatcagt tggttgactt
     5581 acctcttaat ccaaaaaatg acaatcagct ctctgctgaa aggtttttca tctttcaaat
     5641 ttggtctact ctttaattat ttgatgaaaa ttggaactac cattttactg acagtcttgc
     5701 tagttggggt aggaaaaagt ttggagcaag aaaacaaaga gttggattac cagaaacagt
     5761 ggatcagcca aggaaattat ctgaccttag aaactttcca actcaatgac aacttgtggc
     5821 aagagcagtt ggcaggctca gggaaggcat tggattattt ctatcgattt tatcaggatt
     5881 tggtagaaaa aacgcaggcg ggctatgtgc agagtagcag tcttcctgta aaaaattttg
     5941 tccaatcaga acagattcag caatatcagt taacagatac ggtggatgtt tactatgcca
     6001 atcgcaattt tctaaagagc aagggattca agctaccaga taccggtatt aaaaaagtta
     6061 ttttgatgcc agcaagtacg aaaggtgaag aagataaaaa tcagctcttg gggaagttaa
     6121 ttgcctttca ttcgatgaag tatgaagagc agcaaaaacg aacgatagag gagatggatg
     6181 tcgagattgc ctattatgaa ggagattggt catttttccc atatagtgat aagcgaaagg
     6241 aaaatctctc caatccaatt attagcttgg tcaatgattc tgatatgatg tgggatgaga
     6301 aagcctccct gtcaacaact ggcttaaata atccgattaa aattgaaaat acggttcaac
     6361 atcaaaaaga gattacagag ttagttgaga aattgtcaga tggaaattat ttaaaatttt
     6421 catctattca agccattcaa caagagaaag tggattctta tcgagatgct gttcggaatt
     6481 ttaacctact ctttgctttg tttggtctcc ttagcatgat gatttcctac ttcttactag
     6541 taataacttt cttattgaag cgcagggata ttattaccaa gaagtttatg gggtggaaac
     6601 tggtcgatcg ctaccgccct ctcctcgttc tgctcttgct gggctatagt ctgcctcttc
     6661 tagtcttgat tttctttgcc catgcgctct tgccactcct actttttgca ggttttacat
     6721 gtttggatat actatttgtg ctaggcttgg cttctaggat ggagaaaaga agtctagtag
     6781 agttattgaa agggggcatc ttatgattga gttggacaat attaccaaaa ccattggagg
     6841 aaaagtgatt ttggataact tatctctcag gattgatcag ggggatttgg tagccattgt
     6901 tggcaagagt ggtagtggta agtcaacctt gttaaattta ttaggtttga tagatggtga
     6961 ttacagcgga cggtatgaga tttttggtca gacaaatcta gcggtcaatt ctaccaagtc
     7021 gcaaacaata atccgtgaac atatctctta tctatttcaa aattttgccc tgattgatga
     7081 tgaaacggtc gagtacaatc ttatgctggc gctgaaatat gtgaaattgt ccaagaaaga
     7141 caagctcaaa aaggtggaag agattttaga gagagtaggt ttgtcagcta ctttgcacca
     7201 aaaggtctcc gagttgtctg gtggcgaaca acaacgaatt gcagttgcta gagccatctt
     7261 aaaacccagc cagctgattt tagccgatga accgacaggt tctctggatc ctgaaaatag
     7321 agatttggtc ttgaagtttc tcttagagat gaatcgagag gggaaaacag tcattatcgt
     7381 gacccacgat gcttatgtag cccaacaatg tcatcgaatc attgaattag gcgagggaaa
     7441 atgagttcgt tcagcttcat ttgaccgact gaatactcat atttttcaga gagaaatagc
     7501 ataaataggc ctaggaatga tatttttatg tcattttcct gggtttttct gttttaaatt
     7561 gaaaaaaaat tacaatttag gcttgacaaa ggatgcatat agatgtattg tttatacaaa
     7621 caaaaggaat aaacataaag taggctttat tatgaataaa gatgaagaag gtgttgatga
     7681 cgatgtttgg tttagtgatg ctccccctac tatttgcttg tagcaacaat caatcggctg
     7741 gaattgaagc catcaagtcc aaaggaaaat tggttgtagc cctcaatccg gattttgctc
     7801 catttgaata ccaaaaagtg gttgatggga aaaatcagat tgtgggttca gatatcgaat
     7861 tagccaaggc tatcgcaaca gaactaggtg tcgaattgga actatctccc atgagttttg
     7921 ataatgtact ggctagtgtt caatcaggaa aagccgacct tgccatatca ggtgtttcta
     7981 agacagatga acggagcaag gtgtttgact tttccattcc ctactatact gcaaaaaata
     8041 aactcattgt caaagaatct gacttgacta cttatcagtc tgtaaacgac ttggcgcaga
     8101 aaaaggttgg cgcgcagaaa ggttcgattc aagagacgat ggcgaaagat ttgctacaaa
     8161 attcttccct cgtatctctg cctaaaaatg ggaatttaat cacagattta aaatcaggac
     8221 aagtggatgc cgttatcttt gaagaacctg tttccaaggg atttgtggaa aataatcctg
     8281 atttagcaat cgcagacctc aattttgaaa aagagcaaga tgattcctac gcggtagcca
     8341 tgaaaaaaga tagcaaggaa ttgaaagagg cagtcgataa aactattcaa aagttgaagg
     8401 agtctgggga attagacaaa ctcattgagg atgcctttaa agcgtccatt gaaaaataga
     8461 aagaaggaaa agaacatgag taaagaaaaa gtaattttgg cctattctgg cggtttggac
     8521 acatcagttg ctattacctg gctgaagaaa gattatgatg ttgttgcagt ttgtatggat
     8581 gtgggtgaag ggaaagactt agatttcatc catgataagg ctctcaaggt tggggcagtc
     8641 gaatcttatg tcattgatgt taaggacgaa tttgctacag attatgtgct agtggctctt
     8701 cagtcacatg cctactatga acaaaagtac cccttggtat ctgccttgag ccgccctctt
     8761 atttctaaaa aattggttga aatagcgcat cagacaggag cgactacaat tgctcatggt
     8821 tgtacaggta aggggaatga ccaaatcgaa taccagattg cagtcgctaa gaaagcgaat
     8881 gaagctaaaa agtgatggag tgatgggttc agaataagag gttggtcgat tggcagcctc
     8941 tttcttgtcg ttgaaaaagt gagatatatt gacttttgaa aaaaatgtca taattgagtt
     9001 gggataaacg taaaagtcat actttctcgt taaatcgttc ggcgattcat ggtgacatgg
     9061 acacatagta gtaagcacac tatgtggctt agcagagcta aaaacttctg gtttaacaat
     9121 ggctggtatt aagaactaac gaacaaataa tatgtaaaga gtcgaggaaa tccctcgact
     9181 ttttttataa tttctttggt tgataatggg tctctacttc ttttttgaga tgagacagca
     9241 tagaagtttc ctcggtcagc tctaggagtg agaaaccttt ttggataagt ttagcattat
     9301 ctgtacaaat cccaatacgg acatagcaga tagccagcct atcgtagctt ttcttattct
     9361 tggcgtcctc tagtaaagtg tagcagattt gcttacacat gtttttatct tgattgtata
     9421 gatagagtgt ggaaaggttg agcaggattg ctattcgcaa gtcatataaa tgttgatagt
     9481 ttttatagac ttctaggcgt tgcaatattt ttccagtgat gagatggagg tattcaatgg
     9541 gaaaactgaa aagaatggta ttgaggattt ttagatcact ctcataccat gtatcttgtt
     9601 tttcaatttt tctccaaagt tttttgacaa cctgttctgt gtgatctgat agttcccttg
     9661 ccccgtgttg acggatataa atgacaactt caagcatatc tctgatttct tctataggga
     9721 gatcgtggtg ggtcttgagg tagtcttggc atttttgaaa taaattgaca agatcgctgg
     9781 tcccgataat ggaacgcata ttgagatagg tttgcataat ctctgtgcgt tgacttggtt
     9841 gataaagttg acagatatat tcaaactctt caaaactcat attgatttga cggagaagaa
     9901 attccatatt ttcatatttt ggggttgtct tgccactttc gatttttgat aagctggttc
     9961 ttgagagaac acccccacag acctcttctt gggtcagccc ctttgactca cgtatttctt
    10021 tatagacctt tccgaaatca taacgcatga ttttctcctt ttcgtgaaaa aagttaacaa
    10081 acaataaaat tttgttaaaa atattgtatc atagcaatgt aaaaagtaaa aaagaaagtc
    10141 gaaataaatt tgtgaaaaaa gttaacgtaa ttttaaaatg agcttaataa gaggtactat
    10201 gtaggtagaa aataaagata ggagaaaaag tatgaataaa aaaatatttt gtattctagt
    10261 atgtattata ttattgatta gtctggctat aatctttcca tggggctggc cgatataatg
    10321 taagggagtt tgagttgtta aaggaggctc agtccttggg caaaaatctg ctgtactaca
    10381 atgcttggaa agatatcaag aacaaagaat gatacggttg aaaataaatt aattcaagaa
    10441 ctactgggca gtgattgagg tttgggtgac atcaaagaaa agttagatta attctaaaga
    10501 attgagtatt tctatgttaa aaaaatatcc ttgtacgatg caacatgacc agtcagattg
    10561 tgctgcggca gttgtttcaa cagttctttt atcttacaaa aaggaactat caatcatgaa
    10621 gattcgggaa attattggta cagacatgta tggaacgact gtcagtggta ttgtttcagg
    10681 tctgaataag ttgaatttta cagtaaaagc tgttcgagta gcactggaag atttgactcc
    10741 aaaattaaca tttcctgcga ttcttcaagt taagaatgat ttaggtcaaa atcattttgt
    10801 ggtattacat agtataaagg agaaaataaa tggaactcgt attaccaaat aattatgttg
    10861 tgattgatga agaagagatg atgtaccttg atgggggggc tatatatata cccaggtggg
    10921 caattacagg agccattact ggtgcagcat atgcagcatt agcagcagca ggaggtggag
    10981 gccttcaact agttcttgca tcttatggat tacgctccgc actggtagct gggattgtta
    11041 aaggtttagg agtattagga attcatattg gaaatgcttt tgcaaatact gttattagaa
    11101 gtattgcatc tgctggaatt ggtgctggag ctgattggat ttttaccaat attattgatg
    11161 gctgggatgg gcgacgtgat aatcaattga gaataggata atagtattat gatggttgtt
    11221 ttaatttcag ttattgttgc attcctgtac cataaaatta cagagtatgt caacaacagg
    11281 aaaattgata ttgttatttt tctatcattg ctgatttctc attttatttg gaattactat
    11341 tttttaccaa ttgaaatatt gatag
//
LOCUS       DAVKZI010000057        10768 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKZI010000057 DAVKZI010000000
VERSION     DAVKZI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.058"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(137..1561)
                     /locus_tag="VXB18_001920"
     CDS             complement(137..1561)
                     /locus_tag="VXB18_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0383071.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2119..4398)
                     /gene="pulA"
                     /locus_tag="VXB18_001921"
     CDS             complement(2119..4398)
                     /gene="pulA"
                     /locus_tag="VXB18_001921"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0383072.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKSKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4510..6468)
                     /gene="ligA"
                     /locus_tag="VXB18_001922"
     CDS             complement(4510..6468)
                     /gene="ligA"
                     /locus_tag="VXB18_001922"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0383073.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6561..7739)
                     /locus_tag="VXB18_001923"
     CDS             complement(6561..7739)
                     /locus_tag="VXB18_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0383074.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7819..8659)
                     /locus_tag="VXB18_001924"
                     /pseudo
     CDS             complement(7819..8659)
                     /locus_tag="VXB18_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
     gene            complement(8662..10563)
                     /locus_tag="VXB18_001925"
     CDS             complement(8662..10563)
                     /locus_tag="VXB18_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0383075.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEELTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTEKQLR
                     QMELEMGEKSGEDLNKLMSDYDRLSENFHQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMDRLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAI
                     GYDGEVLSEPINLDLRKMNAVAIVGPNGIGKSTFIKSIVEQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3230 a         2372 c         1916 g         3250 t
ORIGIN      
        1 caatgtttta gaagtagagc tgtactattc tagtttcaat atactataat accaaaaagt
       61 tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca ggaaaacaat
      121 ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt
      181 caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga
      241 aattatctgg accacgctgg gttttattat taatgtggac tgtacctact tcaagttttt
      301 cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt
      361 cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa
      421 caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca
      481 ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc tctttttctt
      541 gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata acaggtgtaa
      601 tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag
      661 tagctaattt atctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt
      721 gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat
      781 cttctagtac aagagctgca tctttcccac caagttccaa catgatagga cgcataccag
      841 ctaaacgacc aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt
      901 ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa
      961 cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac
     1021 cttgtgttgg tggcttaaac atgacaacat tccctgcaat caaggcaggt gcaattttag
     1081 aagcagataa attaactgga taattaaaag gagcaatcgc tagcacgata ccaactggtt
     1141 cacgacggac aacagccagt ttgtttttac ttgctgcctc aaaaccacca ccttccattg
     1201 cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca
     1261 ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa
     1321 ttttttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc gcacgttcaa
     1381 ttgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata gcctcatcag
     1441 cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa
     1501 tcgtaatttc ttgttcggat gatttccatt ttccatttac taaattctga tatcttgtca
     1561 aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag aaaataacaa
     1621 ccctttttgc aaaatttttg agattatttt cacaagcttg atttttcaaa gtatactcaa
     1681 taaaaataaa aaaatccact acgtcaaggc gaggctaatg tggtttgaag aaattttcga
     1741 agagcgtgaa tgagtatcat ttatagtaaa ataaaaaaac tgaacaattt ggttggggac
     1801 agccaaacca atttctcaca atgttttaga aacaagggtg tgctattcca atttcagcct
     1861 actataactg tcatagattg ttgaaacaaa gtctaggtaa aagtcttcat aataaaaaga
     1921 cctcctatca aatgttcaaa aactttgata ggaggtcttg tttcgtgaaa atatttatca
     1981 aattttctat acaagtgagc tgttagccag gttcttttag ccaggttctt tctattcttt
     2041 caatttcaat gaatggattt tttatcaata ctcataactg ggaatttgtc tgtgtaaaaa
     2101 tagcgagata gatggtattt ataaaacact caagacagct agactaatat catttaaaac
     2161 attatcttct tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa
     2221 ttgatagggt tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc
     2281 atagataagg cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc
     2341 atcatagcta gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat
     2401 aaactcaata ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc
     2461 aggagcatta tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc
     2521 accagtcgca accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc
     2581 ctgcatgagc agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact
     2641 ttggtctgga tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac
     2701 atagttaagc acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc
     2761 tttagctaga attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata
     2821 aacttctccc cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat
     2881 ctggtaggca ttgtccttct tggacttatc ataaggggca agacctgttc ccatatccca
     2941 tccttctcca tagaggataa tgttggagtc gatttcatcc aagctttgac gaatcatctg
     3001 catggtcttg acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc
     3061 ctgcacccag tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc
     3121 tgtttcattt ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata
     3181 gtaatcaggg actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac
     3241 tacatccata atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc
     3301 acgaatgacc tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata
     3361 gttttgtgga tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg
     3421 acggtctgca attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa
     3481 agcagttgac tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc
     3541 tcgaagatgt tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tgtgcatttc
     3601 acagataact gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac
     3661 ctcgaagttt tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg
     3721 gctggtcgcg attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg
     3781 atactgataa gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt
     3841 attgtcctta tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac
     3901 gggtgcatca ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga
     3961 ccagagggaa aaatgagcct gattgtcctc tacacggcaa cctaattctc cttggtaacc
     4021 ccaatgatga tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt
     4081 tttatagaaa ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc
     4141 caaaatccag acctctgtta ataggggata gtgattaaaa cggatagaat attctttact
     4201 agtttgacct gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc
     4261 aaagctaaat aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc
     4321 ctgacttttt acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg
     4381 catagggtag ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa
     4441 atttttgtca atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta
     4501 aacgatccat tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg
     4561 tgctttttgc agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga
     4621 aacactacct gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt
     4681 gagtcgttcc aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac
     4741 taccgtctgt cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat
     4801 ttcagagcct tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact
     4861 ttcaatacta gccacttcct ctgaatctgc ctgatacaga ttttcaattg aatggaaata
     4921 ttgaagtaaa agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag
     4981 cttctcggca gaattttcct ttgacgcttg gatagcctga tacagtttag cagcggactt
     5041 ttccttaacc ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac
     5101 atccttgact aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat
     5161 attcatagca tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg
     5221 cggattgata caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact
     5281 tggacagttt gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg
     5341 taaaacggca gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat
     5401 atctttttca gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc
     5461 aagttgtact ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca
     5521 gtcaactgat aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca
     5581 ctttggagcc ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat
     5641 taccactcca tcaatatcgt aaggtagatt ttcccgttcc tgtcctactt cttggataaa
     5701 attccagatt tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag
     5761 ttgttctagg tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg
     5821 atagagaaac gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt
     5881 tcctgctgcc gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcgcttg
     5941 gttaacttgg tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag
     6001 ttcttctggc aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc
     6061 accaattgaa ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag
     6121 cgagatagat aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt
     6181 acgaacacgc gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata
     6241 aagaggatac tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg
     6301 agtcggactg tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg
     6361 gtaaaggcgg tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt
     6421 cgcatagcga ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta
     6481 ccataaaaca agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta
     6541 tttttgaaac tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac
     6601 gatatacaag acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca
     6661 ctttgcaaga ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa
     6721 attgtactca gtactctccc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa
     6781 aagtgaatat taaaaatcgt cataaacaat tcacaaacta aatttccaga aaaggaaaga
     6841 aaagttggaa gtggtaatcc catcataaaa actccaacac ctgtcaaagc cagtaaaatc
     6901 aaaagattat aaatattagc tttaatttta ctagctagaa gagccccaat gatggaacca
     6961 atagccccca tagttaaaat acttgcatag gctccttctg acccgtaaag ctgattcgaa
     7021 aaaggaagta gaaattcaaa agctgcaaaa aagaaattaa cgctggaagc taccagcaaa
     7081 aggaagaaaa tttcttgctg atgccagata tagtgtaacc catccttgat atctacaaaa
     7141 atatctctcc cagtaaaagc ctttttctct tgaacttttg cttcctcttt tggaaggaaa
     7201 gccactagaa caaaagcaat gaaaaaagtc agcgagtcta gcagtagcgt catatggaga
     7261 cttgcaaact gtaaaacaag gaaggaaaga acaggagagc taacacctac aacctgcaaa
     7321 accagctcta agcgagaatt atagatcaca atctcatctt tctccaccac ttcagttatg
     7381 atagctttat tggctgtgcg agaaaaggca aaagcaatag cctgcacaat gttagcaaca
     7441 atcaaagcgc caatcatcca gctatcattc cttatgaaag aaatagccag acaaagaatc
     7501 ccacaaacaa gatctgccgt cattaaaatc ttacgacgag aaaaacggtc tgaaataact
     7561 ccgccaaagg gattgacgag aatagatgtg acgagctcag aaatctgata cattcctaaa
     7621 actgtctgtc ctatagtccc catagaagcc aaccagacac tatttccata atcatagagc
     7681 atatttccca ttttattgat agccccacgg ctaatcaact gcactgcata gcgattcata
     7741 ttaaagctcc tctcaaattt tgaaactatt gtatcaaaac cgaaaggagc tttttatttt
     7801 ttcccttatt tgggaaaatt aacttttgac aaatttttcg tagtgttcct gataataggc
     7861 tacttgctct ggaagaccta acacatcaaa aatatgcatg gcctcttgca tctgcttaca
     7921 gccttcttta cactgtcctt tttgatataa ggcaaaacct tttaaataat ggaaaacatt
     7981 acgctcataa agcttaatac ctttgtcaat aatcttctct gtataagcct caaaatagtt
     8041 ggcattataa ctggtaacaa ttgagggcca aaatcaacac taatctctta tggcgactaa
     8101 tctcttggta aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta
     8161 catcgtagaa actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg
     8221 ttttgaagag ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat
     8281 ctctttgaca aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg
     8341 tcgaactctt agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt
     8401 ttgaatagta aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat
     8461 tccttgcctt atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga
     8521 aacgggagac tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc
     8581 aggattcgcc tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata
     8641 cttttccaag atgttccatc tttacacctg atctgataat tcttcccact caagcatagc
     8701 ttcttcctga cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc
     8761 atcgtttgtt tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat
     8821 ttcagcttct agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt
     8881 ctgggcctga tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc
     8941 ctcagtctga ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag
     9001 gtagagagtt gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa
     9061 gtaacgatca tgactgacaa aaagcaaggt accatcaaag tcaatcaaag cattttccaa
     9121 cacttccttg ctatcaatat ccaagtggtt ggtcggctcg tcaaggatca ggaagttgtt
     9181 gttttccata gacaatttag ctaaaagcaa acgtgctttc tccccaccag acagcatgcc
     9241 gactgatttt ttaacatcat ctcccgagaa aaggaaggca cctagacgat tacggatttc
     9301 aacttctggt gtcagtttaa aatcattcca gagttcatcc agcaccgtat tacttggtgt
     9361 cagcttgctt tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc
     9421 acccttgata aaaggaatct gctccacgat agatttgata aaggttgact ttccaatacc
     9481 attgggacca acgatggcga cagcattcat cttacgaagg tctaggttga taggctctga
     9541 caatacttcc ccatcataac caatagccgc attttcaaca gtcaatacaa cattccccga
     9601 cgttttctca gactggaagg tcatgttggc agatttcttg ccagcttcag gcttgtccaa
     9661 acggtccatt ttttccagtt gttttcggcg agattgggca cgtttggtcg ttgaagctcg
     9721 gactagattg cgattgacaa agtcttccag agccgcaatc tccttctgtt gcttttcata
     9781 attttttgcc tcagtagcta gcttctgctc cttcaactca acaaaacgag agtaattccc
     9841 tacatagcga tccaaggaat gcttggtcaa atctagcgta atcgtcgcaa ccttatccaa
     9901 gaaataacgg tcgtggctaa caataatgag ggcaccgcta tagtttacca agtaattctc
     9961 tagccaggca atggtttcaa tatccaagtg gttggttggt tcgtccaata ccaaaagatt
    10021 gggcttttca aggagcattt tagcaagtgc caaacgagta ttttgaccac ctgaaagttc
    10081 agctattttc atctgccaca tagactcgtc aaacttgaaa ccattcaaaa tcgctcgaat
    10141 atcagcttca taggtaaagc cacctgcttg gtgaaaattt tcagataagc ggtcgtaatc
    10201 tgacatcagc ttatttaagt cctcaccaga cttttcaccc atctccagct ccatctgacg
    10261 aagttgtttc tcagtccgac gcaagtcatc aaagacatga agcatctcat cgtagatggt
    10321 attttcagac tcaaaacggc tatcttgggc taggtaagac agagaaatat cttttttctt
    10381 attgatttct ccgctagtta gctcctcttc tccaactaaa atcttcaaaa gagtagactt
    10441 acctgcacca tttttcccaa caagggcaat ccggtctcgt tcatcaacct gcaggttaat
    10501 attatcgaaa agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat
    10561 catacaaaca gtatagcatg tttccctaag gcattcaaga taatcgtaag tattttagcg
    10621 aagaacttgt aacataaaat aaattatgta aaatttgtat tggattcctt cgctatcttg
    10681 ttggattttc taataagcta atcttgcttc aaatagttat cgcacaattc tattatttaa
    10741 ttcttttcat tatatacgta cgtatagc
//
LOCUS       DAVKZI010000058        10187 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKZI010000058 DAVKZI010000000
VERSION     DAVKZI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.059"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..276
                     /locus_tag="VXB18_001926"
     CDS             <1..276
                     /locus_tag="VXB18_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0383076.1"
                     /translation="SDFFEAWFQKFLLPTLNTPSVIIMDNARFHRMGKLELLCEEFGY
                     KLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            242..622
                     /locus_tag="VXB18_001927"
     CDS             242..622
                     /locus_tag="VXB18_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0383077.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(760..2064)
                     /gene="eno"
                     /locus_tag="VXB18_001928"
     CDS             complement(760..2064)
                     /gene="eno"
                     /locus_tag="VXB18_001928"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0383078.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2228..2674
                     /locus_tag="VXB18_001929"
     CDS             2228..2674
                     /locus_tag="VXB18_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0383079.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2671..3786)
                     /locus_tag="VXB18_001930"
     CDS             complement(2671..3786)
                     /locus_tag="VXB18_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0383080.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDLYEKFSPATLEIKGAGAGGDLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3795..4124)
                     /locus_tag="VXB18_001931"
     CDS             complement(3795..4124)
                     /locus_tag="VXB18_001931"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0383081.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4069..4440)
                     /locus_tag="VXB18_001932"
     CDS             complement(4069..4440)
                     /locus_tag="VXB18_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0383082.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4499..5932)
                     /gene="glgA"
                     /locus_tag="VXB18_001933"
     CDS             complement(4499..5932)
                     /gene="glgA"
                     /locus_tag="VXB18_001933"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0383083.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5929..7068)
                     /gene="glgD"
                     /locus_tag="VXB18_001934"
     CDS             complement(5929..7068)
                     /gene="glgD"
                     /locus_tag="VXB18_001934"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0383084.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7058..8200)
                     /locus_tag="VXB18_001935"
     CDS             complement(7058..8200)
                     /locus_tag="VXB18_001935"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0383085.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8190..10118)
                     /gene="glgB"
                     /locus_tag="VXB18_001936"
     CDS             complement(8190..10118)
                     /gene="glgB"
                     /locus_tag="VXB18_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0383086.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3074 a         2252 c         1816 g         3045 t
ORIGIN      
        1 agcgactttt ttgaagcttg gtttcagaaa tttctcttac caacattaaa cacaccatcg
       61 gttattatta tggataatgc aagattccat agaatgggga agctagaact cttgtgtgaa
      121 gagtttgggt ataaactttt acctcttcct ccctactcac ctgagtacaa tcctattgag
      181 aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat taccaagttg caataccttt
      241 tatgaggctc ttttgtcttg ttcttgtttc aattgactat ataaattgtc taagcgaaac
      301 aaccgataag aattggcaca aaagcgaccg tgtttttgtt accaatacag gaaaaacagt
      361 tcatagttct atcttgagca agtctctcca gcgagcaaac gaacgcctta aaaaaccaat
      421 tcccaaacat ctgtcccctc acatcttcag acacaccact attagcatct tatcagaaaa
      481 taaaattcct ttaaaaacaa tcacggacag ggttggtcat tccgactctg aagtcactac
      541 ttccatctac acccacgtca caaagaacat gaaagatgaa gcaatcaatg tactggataa
      601 agttatgaaa aagatttttt aaaaagtttt gccccttttt tgtcctctaa atacaaaaat
      661 agcccttcgg ataaaatccg aggggctaga aacgttgtta aatcaacggc cgaacttttg
      721 aatttcatgg ttcgggataa aatagttcac tgaactattt tattttttaa ggttgtagaa
      781 tgatttcaat ccacgatatt cagctacttc accaagttgg tcttcgatac gaagcaattg
      841 gttgtattta gcgatgcggt ctgtacgtga aagtgaacca gtcttgattt gtcctgcgtt
      901 agttgcaact gcaatatcag cgattgttga atcttcagtt tcacctgaac ggtgtgatac
      961 aacagcagtg taaccagctt ctttagccat ttcgatagct tcaaaagttt cagtaagagt
     1021 accgatttgg ttaactttga taaggattga gttagcagca ccttcttgga taccacgtgc
     1081 aaggtagtca gtgtttgtta cgaagaagtc gtcaccaaca agttgtactt tcttaccaag
     1141 acgttcagta agagctttcc aaccatccca gtcgttttca tccataccat cttcaatagt
     1201 gatgattggg tatttgttaa ccaattcttc aaggtagtcg atttgttctg cagatgtacg
     1261 aacagcagca ccttcacctt caaatttagt gtagtcgtaa actttacgtt ctttatcgta
     1321 gaattctgat gaagcacagt caaatccaat aaatacgtct ttacctggta catatccagc
     1381 agcttcaatc gcagcaagga tagtttcaac accatcttca gttccttcga aacgaggagc
     1441 gaatccacct tcgtcaccta cggcagtttc caaaccacgt gatttaagga ttttcttaag
     1501 agcgtggaag atttcagcac cgtaacgaag ggcttcttta aatgttggcg caccaactgg
     1561 caagatcatg aactcttgga aagcgattgg agcgtcagag tgagaaccac cgttgatgat
     1621 gttcatcatt ggagttggaa gaactttagt gttgaatcca ccaaggtagc tgtaaagtgg
     1681 gatttcaagg tagtcagcag cagcacgagc tacagcgata gacacaccga ggattgcatt
     1741 cgcacccaat ttacctttgt taggagtacc gtcaagtgcg atcatagcac ggtcaatagc
     1801 ttgttgatca cgtacatcgt agccaatgat agcttcagca atgatgttgt ttacgttgtc
     1861 aacagctttt tgtgtaccaa gaccaccgta acgagatttg tcaccgtcgc gaagttcaac
     1921 tgcttcgtgt tcaccagtag aagctcctga tggaaccata ccacgtccga aagcacctga
     1981 ttcagtgtaa acttctactt caagtgttgg gttaccgcgt gagtctagga cttcgcgagc
     2041 gtaaacatca gtaataattg acatttttta ctctccttat gagttaaatt ttttacacct
     2101 ctataatacc ttaaaacccc tcctttttca agaaaaaacg ttatctttgt gcaacttttc
     2161 cttaacttta taaagtaatc gctttctttt gtctgtttta ttctaacttt tatgatatac
     2221 tgttttcatg acagatttat caaaacaatt acttgaaaaa gctcatggtg ggttaaaaat
     2281 aaatccggat gagcaaagac gctatcttgg tacttttgag gaaagagttc ttggatatgt
     2341 agatattgac acagcaaata gccctcagtt agaaaaaggc tttttattta ttttagaaaa
     2401 ccttcaggaa aaagcagagc cactatttgt gaagatttca ccaactatcg aatttgataa
     2461 gcaagttttc tacttaaaag aagcaaaaga aactgatagt caagccacca tagtatctga
     2521 agagcatatt acttctcctt ttggcctggt tattcatagt aatgcaccag ttcaagtaga
     2581 agaaaaagac cttcgacttg cttttccaaa actttgggaa gttaaaaagg aagaaccagc
     2641 caaaacatcc ttatggaaga aatggtttag ctaaatcttg cacatattta ataagtgccc
     2701 aatattggca gccgtgcgct ccagatagag actggcattt ttcaaactat cttctaaagg
     2761 ttcacttttc tccaaaatag aaaagacagc ttggatattt tcaaatggta ggggaggtaa
     2821 atcttcagca agactaccgc aaatagcaat aacaggaact ccaacagggg ttctttttgc
     2881 aacacctata ggcgctttcc cagcaaagct ttgactatca agtcttcctt ctccaacaac
     2941 aaccaagtca gcatctgaaa ctttcttatc aaagttgatt aagtccaagc aggtatcaat
     3001 tccagacacg atacttgcct gagcaaaggc acacaaacca ccagcaaggt ctccacctgc
     3061 tcctgctcct ttaatttcta atgttgcagg tgagaatttt tcataaagat cttggatcgc
     3121 ctgatctacg actgcaaaca tagtcggatg tagacctttt tgattgccaa aagtgtaagt
     3181 cgcaccttga tgaccacata agggactcac gacatctgct aaaatatgaa tttgaacacc
     3241 ttcaggaatt ttatagcgat tttctgttga aacagaagct aagtttaata aggattgacc
     3301 ggaagcaggc aagacatttc catccctatc ataaaattga taacctaaac cagcagcaat
     3361 ccccagtcct ccatcattac tggccgtgcc accaacaccg atataaatat ctttaatccc
     3421 tttagaaatg agatggagaa tcaactctcc aataccacaa gtttggattt gaagtggatt
     3481 tcgtttctct agcggaattt ttccaagacc aaccaagtca gctacttcaa atagtgccag
     3541 ttcccctttt tgaaaatagc gcatggcttc tttttgtcca gaagggtctg tcacttggat
     3601 ccatttttct tttaggtcaa gagaatgtcg gatagcatct acagtacctt ctcccccatc
     3661 accaacaggg cagaggagac attctacatc tgctatcgat tgttggaagc ctctttttat
     3721 tgcttcagct acctgttgag ctgtcaagct ttccttaaac gaatccggtg caattacaat
     3781 cttcatattt tccctcattc taaacagtca atcaaaggaa gaacttctaa aaaatccctc
     3841 ttgtcaacat gatgtggtat ttcttttttg agcatttctt tggaacaaaa ggcgattcct
     3901 aactccgccg acttcaacat taatagatta ttgaccccat caccgattgc caccgttctt
     3961 tctttagaaa gttttagttt ctttctccat ttttccagag tttctttttt gacctgggga
     4021 cttataattt gtccaactaa ttttcctgtt aaaagacctt ctttgacttc aagctggttg
     4081 gcagtgaaat aggcaatacc aagggatttt gctaatctct ccaactattg gtgtaaatcc
     4141 accagacacc agaccaacta ggatgccatt cttttggaga atagagatga actctgggac
     4201 atttagcgat agatgaattg agttgaagac gttatcaaag accaaaatag gaagaccttc
     4261 caacaaggac actctttttc ttaaactgct ttcaaagacc aactctcctc gcattgctcg
     4321 acttgtaatc tgcgaaattt ccgcctcatg acctgcctct ctccctaaaa gatcaatcac
     4381 ttcttctagg attaaggttc catctacatc caaaacacac aagcctttta cttgagacat
     4441 cagttctcct ctctaaacag cctaaaaatc gtatgaagtc atcatacgat tttatctatt
     4501 aattaactaa actatggtac aagtcaaggt atgacttgca ggctgtatcc catgagaagt
     4561 cactctccat agcttgtttt tgtaggtttc tccaaatgtc tggatggttt ctatacaagt
     4621 ccaatgctgt ttggaaagtc caatttaacc aataaggaga tagattgtca aagctaaagc
     4681 cagtaccgct tccttcgatt ggattgaaag cgcgaactgt atctcgcaag cctccaactt
     4741 catggaccaa tggcaaggtt ccataacgca tagccatcat ttgagacaag ccacacggtt
     4801 caaaacgact tggcatgagg aagaggtcac aagcagcgta gatttcctga gcaagtttga
     4861 catcaaaagt gatatttgtt gatagcttgt ctgggtaaat ctgagcaaac catgagaaag
     4921 ctccttcaaa ggctggatcg ccagttccca aaagaacaat ctgaacatct tcttgcaaga
     4981 tatggtgaag actttcgacc accacatcaa aacctttttg acgtgtcaaa cgagaaacaa
     5041 ttcccaccag tggaacgtct gctctaacag gcaagccaac tctttcttgc aattttgcct
     5101 tatttttggc tttcccagac aaatcttcct gattgaaatg atagtctaaa agagcatccg
     5161 tctgaggatt ataaagatca gcatcaatcc cattcacgat accagatact ttaccagact
     5221 ccattttaag aatctgatcc aaattacatc caaactgact agtcataatt tcatgagcat
     5281 agctaggtga aacggttgaa acacggttcg catagagaat acctgccttc atccagttca
     5341 gacagttgtt ccatcgaagg gtgccatcag cgtaacgttc aaagccaact ccaaacaaat
     5401 cacccaacat tccttctgaa aattgtcctt ggaattctaa attatgaatg gttaaaactg
     5461 tttcaatgtc ctcataggct tgaatccaac ggtatttttc cttcaacaag aaaggaatca
     5521 tagctgtatg gtagtcatga acatggagaa gatcaggaat aaagtcaatc ctttccatag
     5581 cctcaatggc agccagttgg aaaaaggcaa agcgttctcc gtcatcaaaa tcaccgtaaa
     5641 catgaccacg gaagaaataa tattgattgt caataaagta gaaggttaca ccatttaata
     5701 ctgttttctt aattccacaa tactgtctgc gccaaccaac gctcacctca aaatgaagta
     5761 catcttcaat ctgatttcca aatttagcct ctaccatatc atagtagggt aaaatcactg
     5821 caacttcgtg cccagctttt accagtgatt ttggaagagc gccaatgacg tctcccaaac
     5881 cacctgtttt tgaaaagggt gcaccctctg ctgctacaaa taaaattttc atgaatgaat
     5941 atcctctgtt actttagcac ctttcttaac cacaactgga tgttctgcag ttcctcgaat
     6001 cacaacacca ggctcaactt caaccccttt gtccaagata gcatattcga cctgagcccc
     6061 ttctccaata acaacacgag ggaagagcag gctatcttta accaagctat ccttatggac
     6121 atgaatatta cgtgatagaa cagaattagc tacttgacct tcaataatac taccagaggc
     6181 aaactgagaa gtgcttacct tagatgtatt agcatagtaa gttggctctt cgtttttgac
     6241 ctttgtataa atcttttggt ttggtgagaa aagagaatag aatttttgtg attcaagcat
     6301 atcgatattc gcttgataat aagatttaac agagtgaata ttggctagat agcccgtgta
     6361 ctcgtaggcg aaagctccct cttttacagc caaatcccgt aaaacatagc gcaatttctt
     6421 tggatgttct tttttagctt cttcttccaa gtgttcaatc aaccaaggtg tatcaacgac
     6481 aaagatatct gtagacatat tgaacgtttc agctgttgac ttgctatcaa agagtttatg
     6541 agaaagaaca tggtctgttt catctacatc caagattgca tttacttctg aaatatcttt
     6601 cttagctagt tttttataaa ctacagtgat aggctctttt gttgtactat gtaggtggaa
     6661 aacttggttc aaatcaatgt taataagaac atcgcagttg agggcaaccg tttggtttga
     6721 gccagaacgt ttcaaataag taagaagctg ttggtagtat tcttttccaa ctgtactact
     6781 ttctacacgg gtattgtaaa ttcctagata gtaatgacta agaagggttg ataagcccca
     6841 ctcgcgtcct gaacgaatat ggtcaaatac tgagctgata ttatcctgct ggaaaatacc
     6901 aaagacacta cgaacacctg cattagcaag gcttgaaagt gggaagtcaa tcaaacgata
     6961 tttcccacca aatggcaaac ttgctactgg acggtggtcc gtcaatgtcg acatattgtg
     7021 aaaaccaact gtatttccta aaatggcaga atatttatca atcttcatct gttgctaccc
     7081 ccactacttc attatatcct acaacttgta cttcatctgt tccatcaatt tcgacaccgt
     7141 cagaaataat cgcaccttca ccaataatgg cacgtttaat cttagctcct tgaccaatga
     7201 tagctccact catgataact gaatcaagga cttccgctcc ttcgcgaact tgcgcgcctg
     7261 ttgaaaggat agaatgttta acagttccat caacgaaaca tccgtctaca actaatgagt
     7321 cttccacatg agcatttgcc ccgaggaagt ttggtggtga aatcaagttt cttgagtaaa
     7381 tcttccattg acggttacga ctatccaagg cattttctgg agaaatatac tccatgttcg
     7441 cttcccaaag tgactcaata gtaccaacat ctttccaata accactaaat tcgtaagcat
     7501 aaacactttc acctgactca aggtaatttg gaatgacatt tttaccaaag tctgacatgc
     7561 caaccttgct cttttcagca gcgactaaca tattacgaag gcgttgccaa tcaaaaatgt
     7621 agattcccat agaagctttt gtagatttag gttgagctgg tttttcttca aattcaacaa
     7681 tacgattgtt agcatctgtg ttcatgatac caaaacggct tgcttcttta agagggacgt
     7741 ctaaaactgc tactgtcaag ctggcattat tatccttatg agactggagc atatcatcat
     7801 agtccatttt gtagatgtga tccccagaca aaatcaagac atactcagga ttgacactgt
     7861 cgatatagtc gatattttgg taaatagcgt gactagtccc ctcaaaccaa cgatttcctt
     7921 cacttgcaga ataaggttga agaatagaga cacctgaatt aataccgtct agtccccagc
     7981 ttgaaccatt cccaatatgg ttgttgagag caagtggttg atactgtgta acgaccccaa
     8041 cattgtgaat ccctgagttg gcacagtttg atagggcaaa gtcaatgata cggtagcgcc
     8101 caccaaattg cacagctggt tttgcgatgc tttgagtgag tttaccgaga cgagttcctt
     8161 gcccaccagc aagaatcaaa gctaacattt catttttcat tttctactcc tttttggttt
     8221 ttatttgtga cggttttagt agatttcaag cgacgtttga ttttccatac acttgctccc
     8281 atagccggta gggtaaaggt taaggtctgc tcataatctt tccatagtcc ttcttgcgtt
     8341 tgaacagttt gattatgttc tttccaaacg cctccccact cttccaactc agtattccat
     8401 acttcttcgt aaattcctgc aacgggtagt ccgattgtaa aatctttccg ctcaacaggt
     8461 accatgttaa agatacagac taacatttct ccctttttac ccttacgaat aaaggaaaga
     8521 acactctggt ctcgattatc cgcatcaatg atttcaatac catcatagct ggtatcgatt
     8581 tcccacagac agcgatgatc tttgtaaaac tggtttagct gagaagtgaa atacttcatc
     8641 ttagcattca ttgggtcttc taggttagac cattccaact gttcttcaga tttccattct
     8701 aggaattgac cgtattcgct acccatgaag agcaatttct taccaggatg acaaatttgg
     8761 tacgtataga gattgcgcaa gcctgcgaat tgattgtaac gatctcccca catcttatgc
     8821 atcatactct tcttgccatg aaccacttca tcgtgcgaga atggcaagag ataattctcc
     8881 ttgaaaacat acataaagct gaaagtcacc aggttaaagt catatttacg atagatcgga
     8941 tcttcttcgt agaaacggag gatatcattc atccagccca tgttccattt gtagtcaaat
     9001 cctagaccac caatctcttt cattcccgta atcttggtcg cagacgaact ttcttctgca
     9061 atcatcatca catctggata ttctaactta ataacctcat tcaagcgttg aaggaaataa
     9121 taaccttcat agttgagatt tccgccatct ttattaggtg tccatggagc atcatcatag
     9181 tccaaataga gcatgttgct aacagcatcc acacgaatac catccaaatg atagacatca
     9241 atccaatgct taatgcaaga aattaagaag gactggactt cattttttcc aaggtcaaaa
     9301 ttaagggcac cccaaccatg gttatgagcc ttattatggt cttggtattc aaaagtcggt
     9361 gtcccatcat aataggctaa ggcatcatcg ttgatggtaa agtgacctgg tacccagtcc
     9421 acaataaccc caatattatg ggtatgacac tcctcgacaa aatcttgaaa ctcctctggt
     9481 cggccataag catgctctaa agcgaagtaa cccataagct ggtaccccca actcaaacct
     9541 agtgggtggg acatcaaggg cataaactca atatgagtat agttcatctc aactaggtaa
     9601 ggaatgagtt catctttcaa ttgggcaaaa ctataaggac tgccatcagg atttctcttc
     9661 caagagccag catgaacctc gtaaatattg acaggacgtt cagcaaagcc ccaacgtttt
     9721 cttcgtgcca gccaaagtcc atccctccat ttcttatcag gaagctctgt tacgattgcc
     9781 cctgttcctg gacgagcctc atacctgaca gcaaaagggt caatcttcat cagttgatga
     9841 ccattttgac gtgtgacatg atatttgtaa atatgccctt cttgagccat attggtaaag
     9901 acttcccaga ccccaaagtc atttcttacc attggaatct gattttcaat ccaattggta
     9961 aaatcaccaa ccaagtgaac agcctgagca ttaggtgccc aaacacggaa ggtatagcca
    10021 tactctccat ttagttcttc cctatgtgct cctagataat gttggagata aaaattttca
    10081 cccgtcataa aggtttttaa tgcttctcta ttatccatat actccctttc tcctgtaagc
    10141 gttttctatg tttttattat actacctttt tagagaagat tcaagta
//
LOCUS       DAVKZI010000059         9912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKZI010000059 DAVKZI010000000
VERSION     DAVKZI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.060"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(98..610)
                     /locus_tag="VXB18_001937"
     CDS             complement(98..610)
                     /locus_tag="VXB18_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0383087.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(635..1209)
                     /locus_tag="VXB18_001938"
                     /pseudo
     CDS             complement(635..1209)
                     /locus_tag="VXB18_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(1222..1626)
                     /locus_tag="VXB18_001939"
                     /pseudo
     CDS             complement(1222..1626)
                     /locus_tag="VXB18_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1677..1763)
                     /locus_tag="VXB18_001940"
     CDS             complement(1677..1763)
                     /locus_tag="VXB18_001940"
                     /inference="COORDINATES: protein motif:HMM:TIGR01168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0383088.1"
                     /translation="MKIGQRIMRFGIKKLNIGVVSVAVGFDF"
     gene            complement(2070..2879)
                     /locus_tag="VXB18_001941"
     CDS             complement(2070..2879)
                     /locus_tag="VXB18_001941"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0383089.1"
                     /translation="MTFLNKIHETATFLKEKGIQTPEFGLILGSGLGELAEEIENPVV
                     VDYADIPNWGRSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGYGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSKAYTP
                     EYRATAHQVAKKLGIKLDEGVYIGVTGPTYETPAEIRAYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(2876..3436)
                     /locus_tag="VXB18_001942"
     CDS             complement(2876..3436)
                     /locus_tag="VXB18_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0383090.1"
                     /translation="MTCYALLVRGINVGGKNKVVMAELRQELTELGIEKVESYINSGN
                     VFFTSTVPKARLIEKLETFFAVHYPFIQSFSLLSQEDYEAEVENLPAWWNEDLARKDV
                     LFYTELLDVEQVITTVESLELKDEVVHFGKLGIFWGKFSEESYPKTAYHKYLLKMPFY
                     CHITIRNAKTFDKIGQMLKNNKGDTQ"
     gene            complement(3438..4649)
                     /locus_tag="VXB18_001943"
     CDS             complement(3438..4649)
                     /locus_tag="VXB18_001943"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0383091.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVPAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGVIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(4663..5346)
                     /gene="rpiA"
                     /locus_tag="VXB18_001944"
     CDS             complement(4663..5346)
                     /gene="rpiA"
                     /locus_tag="VXB18_001944"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0383092.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHIVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSKKGK"
     gene            complement(5644..6483)
                     /locus_tag="VXB18_001945"
     CDS             complement(5644..6483)
                     /locus_tag="VXB18_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0383093.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(6497..7318)
                     /locus_tag="VXB18_001946"
     CDS             complement(6497..7318)
                     /locus_tag="VXB18_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV0383094.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(7455..8312)
                     /locus_tag="VXB18_001947"
     CDS             complement(7455..8312)
                     /locus_tag="VXB18_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0383095.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(8466..9200)
                     /locus_tag="VXB18_001948"
     CDS             complement(8466..9200)
                     /locus_tag="VXB18_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0383096.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(9200..9883)
                     /locus_tag="VXB18_001949"
     CDS             complement(9200..9883)
                     /locus_tag="VXB18_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0383097.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
BASE COUNT         2890 a         2287 c         1740 g         2995 t
ORIGIN      
        1 aattttgttc tttcacagag agctacctga gttctattca agctcagata gtactttctt
       61 ataaactaga caaactaact gtcattgtac catcagatta caagacatca tcgtcactca
      121 ccttggaatt caatgtcgta ccccaatggg taattttacg gtggggttga gctaaaattg
      181 gtctgttttc atagattgtt tgccatctat tccatagtag gcccgtcttt ttctcaatct
      241 taactcgcag atttctcata ttttctttga ttgggaagtt gaggacaaaa cctgcagtct
      301 ggttgcaacc gtttccttcc caagaatgac tacgaacaac ttggtttcca tctttatcta
      361 ctggaacttc ttcccaagtt atggagtagc gggcaatgta agctccactg tgttgaattg
      421 tcaatgtttt atctttcaca ggagtctgac tgattggttg aactggctta gaaacttgtg
      481 tcgccgtttc agcattcgta gctataaagc ggaaaacttc aacttctgca agactgaggg
      541 cattatagcc ttctagctca atccgaacat agcgcacttt tttatggtta atcgtaattt
      601 gtgctgacac atctttagga gatgttatac gtttttactc aatttcttta ccagaactgt
      661 ctaaaagaat gacatcaaag tttgccaatc tatcctgggc agtgtctgtt cggttgtaaa
      721 tattgatttg gcgaatggtt tcttctttag ccaaatctac ttgccaccaa ggcttagatt
      781 ggaagtttgt atgagtgaca gaattgtgac catagttacc atcgactttg ccatccacag
      841 ctcttctagc atctcctccg aaaactgtcg aactttgagt aacctgtttt cctaaggcaa
      901 tattttccat tggttcagcg cttggttgac tagaagatcg aggcagagcc tgtttcttaa
      961 agaatcgcac tttatccaat ttcggatcac gataaccatg tttatccaag gtagcttgtt
     1021 taccaatatt aaagttagga atatcattca ttggactttc aaaatagcca cgagaacggt
     1081 gtttaaagcg tgaattacct gtaaatgtaa caatatcacg attattatga atcaagggag
     1141 tcacaacatt gtcattatca accacataat gcttaatttt ccactaacag ctaatttacg
     1201 actttccaaa ccaacatccc agaaaccatt cttagcattc caaacagttc tggaagtaat
     1261 gactttagga gcactgaaag ttgtcacttt cctcaataca tggttataaa aatcaggata
     1321 tttttggtaa gcttcaacct ctgcaatctg agctaggtag catccaagag aatgacctgt
     1381 catatacaac ttagtaatac ttatatcctt ggctaattcc ccaacaacct tgcggatatc
     1441 atccgcttga gctggctctg ttatctctac ttttgactct tcccttttgt tttcaaggac
     1501 ttcacttgct tccagaagcg tttgaggagc tagtcttggc tcctctctaa gaggagtttc
     1561 tagttttgga gcatcatttt ctgactcttt caattcctcc ttagaatcta gtacacctat
     1621 taccacttca gatgttacat cttgctttac ttcattggct gaaattccag ctggagctag
     1681 aaatcaaagc cgactgcaac agatacaacc ccgatattta atttttttat gccaaagcgc
     1741 ataattcgtt gaccaatttt cattattctt tatctttctt ttcgtttatt tgtaagcaga
     1801 ctcaagcgaa atctccttgt cccctatata ggacaaggct aagaaattca gaaagtaaat
     1861 tcattcttat ctttccttat catcctagtc tgcttggtag gaagctaatg ctagtatcct
     1921 agaatcttgt ctttcacaat gctaactatc agactctttc agttacaaga gtaggaagaa
     1981 acccatagtc tacctatgtt tcttatttgt tccgaatagc cagtcaatca tgaaaaggta
     2041 gaggtattcc cccttttaaa tcttttttct tacaattcag caagaatcgc tttaagcaag
     2101 cccttgaagt cacctttgac acgttcggtt acttccacaa cttcttcgtg gttgagttct
     2161 tcttggaaac cagccgcaaa gttagtaata catgaaattc ccagaacttt caagccagag
     2221 tgggctgcca cgatcacttc aggaaccgta gacataccaa ctgcatctgc tcccagtgtc
     2281 ttataggcac gaatctctgc aggtgtttca taagtcggac cagttacacc gatatagaca
     2341 ccttcatcaa gcttgatacc aagtttctta gccacttgat gggcagtagc acggtattct
     2401 ggtgtgtagg ctttagacat atcagggaaa cgtggaccaa agtcatccaa gttttcaccc
     2461 atcaatggat tttgccccgt catattgata tgatctgaaa tagccatcaa agtaccaggg
     2521 ccataaccaa taccaccagc tgcattggtt acaatgacac cttcacatcc aagaactttc
     2581 atgacacgta ctgggaaagt cacaacttcc agagggttcc cttcgtagaa atggaaacgc
     2641 ccttgaagag ctaagacctt gcgacctgca aggtcaccat ataccaattt accagcgtga
     2701 ccaactactg ttgaacggcc ccagtttgga atatccgcat agtctactac aactggattt
     2761 tcgatttctt ctgccagttc tccaagtcct gatccaagga ttagaccgaa ctcaggcgtt
     2821 tggattccct tttctttcag gaaagtagca gtttcatgga ttttgtttaa aaatgtcatt
     2881 gtgtgtctcc tttattattt tttagcattt gaccgatttt gtcaaaggtt tttgcattgc
     2941 gaatggtaat gtggcaatag aaaggcatct tgagcaagta cttgtgatag gcagtcttag
     3001 ggtaggattc ttcagagaat ttcccccaga aaataccaag ttttccaaaa tgaacgacct
     3061 catctttcag ctctaaactc tcaactgtcg tgatgacttg ctccacatcc aaaagctcag
     3121 tgtaaaagag aacgtctttt cgtgccaagt cttcgttcca ccaagctggt agattctcca
     3181 cttctgcttc atagtcttct tgactcagta gggaaaaact ctgaataaat ggataatgga
     3241 ctgcaaagaa agtctctaat ttttcaatca atcgggcttt gggaactgtc gaagtaaaga
     3301 aaacattgcc actgttgatg tagctttcaa ccttttcaat tcccaactct gtcaattctt
     3361 gccgaagctc agccatgacg accttattct taccaccaac attgatgcct ctcaccagca
     3421 aagcatagca tgtcatctta taccaattta tctaagaaac tttccccaat catggcagtt
     3481 tccacaccaa agttatcggc aacagtcgct gaaatatctg caaaatgtcc tactggaatg
     3541 acaccatttc ctttaaaagc aggactgtaa gccaaaagtg ggatatattc gcgagtgtgg
     3601 tctgttcctg cgtaagttgg gtcgttcccg tggtccgcag taatcaagag aaggtcgttc
     3661 tctcgcatgg ctgcgataat ttcaggtaag cgttcatcaa actcatgcaa gcaatcacgg
     3721 taaccgtgag cattacgacg gtggccgtaa agggcatcaa agtcaaccag gtttgtgaat
     3781 gagaatcctt tttcaaactc agcaagtccc atagtcttca atagtgtatc aattccatgg
     3841 ctgtttgact tgttatggcc catgtcgtgg ttgataccgg caccgttaaa gatatcgttg
     3901 attttaccaa cagcataagt atcgatacca gcctcattca atttatccaa aacagttggg
     3961 gcaaatggag atacagccaa gtcacgacgg tttgccgtac gagtgaagtt acctggctca
     4021 ccaacatatg gacgggcaat gatgcgacca agaagggcag gacgctcaag ggtaatcgaa
     4081 cgagcgtatt cacagatacg gtacaattca tccagaggaa tgatgtcttc gtgagcagca
     4141 atttgcaaaa cagggtcagc tgaagtatag ataatcaact ctccagtttc catctgacgt
     4201 ggtccaaaat catcgataac ggctgttcct gagtaaggtt tgttagcttc acgaatgacc
     4261 ttacgtcctg aaaattcttc gatttttgtc aggatttctt ctgggaatcc gttccagaaa
     4321 gtatcgaaag gctccgtaat gttgagtccc atgatttccc agtgcccagt catggtgtcc
     4381 ttaccaaggg acacttcttc caattttgtc gcatatccag ttggattgct ttctgccggt
     4441 acagtcttaa gaggagtttc acgaggaata tttccaagac cgattttagc catgtttggg
     4501 acattcaaac caactgtttt tgaaatgtgt cccagtgtgt cagaggcacc atctggaacc
     4561 cctgcattga caaagttatt agcatctggt gctgcaccga ttcctacaga atccagtacc
     4621 accaaatgaa tacgattaaa tttagacatc ttatgccccc ttctattttc ctttttttga
     4681 agttaaaatc tgaactccat ctcgtccagc aacgattacc ttatccacca tttggttgaa
     4741 taaaccgtgc tccacaacac caacgatatg gtccaattct tgtccaaaag caattggatt
     4801 ttcaatgaca tccaaggcga ggtcaatgat aaaattctgc atatccgtca caaaacgttg
     4861 gccatctttt tcacggaaac ttggtttgta gccagctcgt tcaaaacgac gaaagacctg
     4921 ttctgcacca tactgaacca cttctactgg caatttaaaa gcacctagtt tttcgaccag
     4981 cttgctttca tccaccaccc aaatgtattc ttttgatggt gtcgcaacaa ccttctccat
     5041 cagaagagca ccaccaccac ctttgattcc attaaactga ctatccactt catctgcgcc
     5101 atcaactgtc acatcgacaa agtctacttg gtcaatagat ttgagtggga tattaaggcc
     5161 ttctgcctgt ttagtggtca cactagaagt cgttacagct ataatctgca atccttcttc
     5221 cttgatacga cgaccgattt cttcgacaaa ataataggca gtcgagcctg ttccaagtcc
     5281 aacgaccatt ccatccttga caaactcagc agccttgata cctgccattt tcttcagatt
     5341 ttccactcaa acacctccat taaagagcta cctctattat accatgtaaa ggcttttatt
     5401 tcatctaaaa gtacctttag aatactgctt atttatcctt gaaattaaat ttttttaata
     5461 aaagcagaac tctgacaaat cactttaagt acggatgtaa accaaatcaa ctctaacaaa
     5521 aatagattta caagagtaaa aaaacgaaca aatttagttt cttagcgaga agaatactaa
     5581 acgttcgttt tttgtgaatt aagaataatg atacaaatta tcaatatttt ttgtctaact
     5641 attttagaca tatcttttca ttactttagg aagacaatta ctaatctccg ttggcaaaac
     5701 cacatactgt tcttgagcta gttcttgggc tatggctgaa tgaagatggg tcgctactgc
     5761 cacacgttcg taaagactag cttgcttaaa ctggcctgca aatcctgcaa tcatcccagc
     5821 aagcgtatct cccattcccc cagtcgcctg atagggaccg ccaacctgta actggtaata
     5881 atctgattgg ccagcttgcc aaatacgagt agctgaacct ttctccacca aaattgttcc
     5941 ttgagggaag gaagttaggg cactagccgt tgcatcttcc ttttgctttt caatcgtaat
     6001 tccagataat ttttcccatt ctttttggtg aggagttagg ataagctggc ttgaggaaaa
     6061 tgacaaactt gtcctagcaa gaatggtcaa ggcacctccg tctacaatca aaatctgatt
     6121 ttgtcttaag ccagcaaaga cctgtttaac tagatcttct ccaaaagcat cgtctcgtaa
     6181 acccggcccc agcaagacaa cttctgcctt ctccaattgc tcttttaaca actgctggtc
     6241 ttgaagagaa aaggccatag cctcaggtaa atggctgtgc agggctggaa tattttccct
     6301 atctgttcca acggtcacca atcctgcacc gctttttaca gctgccaaag cagccatgat
     6361 gatggcacca ccataaggat aagttccacc aagaaacagc agacggccat agtctccttt
     6421 atgactagta cgagaacgtt caataataac tttttctagt aaggcttgat caatcacttt
     6481 catcgttctt cctcaactat cctttatctg attgttttaa aacaacttga tagactttct
     6541 tagtccactc ttctaagtct tctccagcat agtcaagata atgcacccta tcttgtattt
     6601 tagttggaat aatattttca aattggctct tattatgagt tggaataata caaatataca
     6661 actcactaaa taaattcaac atgtccttaa tttttgcaac atggtagcca tcaaaaatat
     6721 aaccagtaac tttaatcaaa tctgtataga taaaatgaaa actcactcca ggaataaact
     6781 tgtcttgtaa ttctttctct gaaggagctc gacctaataa acgctccatc gctaatcgat
     6841 aaccagaact tgtatttgac caccctaaca tgacataatc aaaataatct atcggatccg
     6901 atgcagcatt tctactatcc aaaaccaact cttcagcatc tcgcctaaag gctttcacag
     6961 cagataagag ctgacctgtt ttaaagatag aaatcgctgc atctatagtc gtagtatgac
     7021 tacagtagtc tgaagtcact aacctcttat gtagatcata agtcgaggct actcttttat
     7081 ctgtaggggt aaatggtggc agaaagggat gctgacagat gtaatctaaa atttcttttt
     7141 ttaaacaaga atcagcacac tcaatacttg tttgacgttt atgaagtttt tcgtaagcta
     7201 taaatttagc aattttttct aattcccact cttgaatatt tggataatca attagtgcta
     7261 ggtagtatat tccatcccat tgtaaactat attccctatt ataaattttt aaaatcatct
     7321 aatcacctca ctccattata caacaaaaag gaggcgcaga cctccttttg taatcttata
     7381 tctaaaattt aatattcatt tctgccattt taaatatagc tatagaaaat acactctctt
     7441 cagcgatttt tctcttattt tctatccaat gtccgaagtg ctgcttgata agtttgctcc
     7501 atcagcatag taatggtcat agggccgaca cctccaggga ctggcgtaat atagctagca
     7561 agtggggcaa ctgcctcata atccacatcc ccacagagct taccattttc atcacgattc
     7621 atcccaacgt caatgactac cgcacctggt ttgacaaagt cagcagtcac aaacttggca
     7681 cgaccgattg cgaccaccag aatatctgct ttagcagcca ccttagcaag attatgggtg
     7741 cgtgagtggg tcaaagtcac tgttgcattc ttggccaaaa gaagctgagc catgggtttt
     7801 ccaacgatat tagaacgacc gatgacaacc gcatttttac cttctaattc aatcccatat
     7861 tcatgaaaca tttccataat tcctgcaggt gttgatggaa tcatgactgg atgtccagac
     7921 caaaggcgtc ccatatttag aggatggaaa ccatccacat ccttttctgg gtcaatagcc
     7981 aatagaaccg cctcttcatc aatgtgtttt ggtaatggca actgaaccaa aatcccatgc
     8041 caagctggat cctgattgta tttagcaatc aggtctaaca attcctcttg agtaatggtc
     8101 tctggaactc gcactacttc gctacgggaa ccagccgcaa gagctgacct ctccttgttg
     8161 cgaacgtaga cttggctggc tggattatcc ccaaccaaaa tcactaccaa accaggcact
     8221 agagctgttt cttcctttaa ttttgcagtc ttttcagcca actgcccctg caatttggcc
     8281 gctaaagctt tcccatcaat aatctgtgtc atatcacttc tcttttcttt caaatatctt
     8341 ccattatacc aaaaactgct agtgccctct aacacttctt tcctaggtta tcctatagtt
     8401 tcaaactata agaaaaagct ctggttgaac ttttcactaa tcttgtcttg aaattttaaa
     8461 atagattata aaaccttact caagaaatct ttagtccgtt gttcttgggt ttgttcaaaa
     8521 atctgctcag gtgtcccatc ttcaacaacc acaccgtctg ccataaagat aacacgatct
     8581 gccacctcac gggcaaatcc catctcatgt gttacgataa ccatagtcat ccctgacttg
     8641 gcaaggtctt gcataacagc caatacctca cctaccattt caggatccaa ggctgaagtt
     8701 ggttcgtcaa agagcaaaac atctggttcc atagccaacc cacgcgcgat ggcaatccgt
     8761 tgttgttgcc cacccgacag actctgtgga taagcgtctg ccttatctgg caaaccaact
     8821 ttttccaaaa gctcttgggc tctcttctca gcaacttccc tgctttcacc tttagtcttg
     8881 ataggtgaca aggtaatatt ttccatcaca gtcatattag gaaagaggtt aaattgttgg
     8941 aaaaccatgc ccatcttctc acgcatggca aacaggtcat tcttcttgtc cgtaatatcg
     9001 actccctcaa agataagctt ccccttggtt gcttcctcca acaaattcat agagcgaagc
     9061 aaggtagatt tcccactccc tgaaggaccg atgataacga caacttctcc tcttttaatc
     9121 tcgaggttga tgcccttcaa tacttcattc tttccaaaag atttatgtaa attttcaatt
     9181 tttatcaagg tttctgtcat tatttcttat ctccttgtcc catatgtttt tcaaaagctt
     9241 tcaaggctac tgtcagaata gaggtcataa tcaagtagta aaatgctgca aataaaagtg
     9301 gtgttaaagg tagataggtt gttgtagaaa ctgttgtagc cccattccac aactccatga
     9361 ccccaatagc tgataagagg gagctgtcct tgataatggt gataaattcg ttccccaatg
     9421 ctggcaagat atttttgact gcttgtggca aaatcacata acgcatcgca tttttaggac
     9481 gaatccctag cgaataagcc gcctctagct gaccttttgg aaccgcattg attccggcac
     9541 gaacagtctc cgaaacataa gcaccactat tcatagagat aatcaaaatc cctggaatca
     9601 gacgcgaaaa atcaacacct aaaattccaa tctgaatagt cggagcattg atatgcataa
     9661 gagcaaaggc aatcataatt tgaaccatca tcggtgtccc acggaaaatc caaacgtaca
     9721 agttggccaa ccaaacaagc ggtttaaact ttgaacgttg cccaaaagcc aagacaacac
     9781 ccaaaatagt tcccaaaaag ataacacaga tagaaataag aatcgtcaca acagccccat
     9841 agttaaaata aggtaaatac ttaggtaaaa aagaaaaatt catagtcaca ctgctttcta
     9901 aaatagaata ct
//
LOCUS       DAVKZI010000060         9702 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKZI010000060 DAVKZI010000000
VERSION     DAVKZI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.061"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            203..298
                     /locus_tag="VXB18_001950"
                     /pseudo
     CDS             203..298
                     /locus_tag="VXB18_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(551..1171)
                     /locus_tag="VXB18_001951"
     CDS             complement(551..1171)
                     /locus_tag="VXB18_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0383098.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1171..1653)
                     /locus_tag="VXB18_001952"
     CDS             complement(1171..1653)
                     /locus_tag="VXB18_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0383099.1"
                     /translation="MAKKVKIKKTLVEQILSKSAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKYLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1653..2495)
                     /locus_tag="VXB18_001953"
     CDS             complement(1653..2495)
                     /locus_tag="VXB18_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0383100.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2590..3390)
                     /locus_tag="VXB18_001954"
     CDS             complement(2590..3390)
                     /locus_tag="VXB18_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0383101.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEKTFRKLFLKP"
     gene            3534..4913
                     /gene="glmU"
                     /locus_tag="VXB18_001955"
     CDS             3534..4913
                     /gene="glmU"
                     /locus_tag="VXB18_001955"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0383102.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4923..5468
                     /locus_tag="VXB18_001956"
     CDS             4923..5468
                     /locus_tag="VXB18_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0383103.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5480..5794
                     /locus_tag="VXB18_001957"
     CDS             5480..5794
                     /locus_tag="VXB18_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0383104.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5811..6503
                     /locus_tag="VXB18_001958"
     CDS             5811..6503
                     /locus_tag="VXB18_001958"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0383105.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6580..7071
                     /gene="rocS"
                     /locus_tag="VXB18_001959"
     CDS             6580..7071
                     /gene="rocS"
                     /locus_tag="VXB18_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0383106.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7169..7759
                     /locus_tag="VXB18_001960"
     CDS             7169..7759
                     /locus_tag="VXB18_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0383107.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7768..9531
                     /locus_tag="VXB18_001961"
     CDS             7768..9531
                     /locus_tag="VXB18_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0383108.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2998 a         1675 c         2071 g         2958 t
ORIGIN      
        1 ttttataatt ttaaagactt tttgactagc ctcatttttt taacttgata ctcagtgaaa
       61 agcaaagatt aaactaggaa gctagctgta ggctgctcaa agaacagctt tgaggttgca
      121 gataaaactt gtgaggtaac caacatatat aatgtgaagc tgacgtggtt tgaatagatt
      181 ttagaagggt atgagtctgg aagttttaat ggataatgca agattccata gaatgggtaa
      241 gctagagttc ttatgtgaag agtttgggca taaactttta ccttttcctc cctactcatc
      301 ttagtataga aaagtgaatc taaaatagta cataactgct tctaaaacat tcttataaat
      361 tgatttaaat tctcaaatca tattattcag ttcttatttc attttgctct acaatcctgt
      421 tgagaagaca cgtgttcata tcaaaaaggt attggcaagt tgcaatacct ttttacaagg
      481 ttcttttgtc ttatttttgt ttcaactgac tatatctcct atggttctag ttcagaaggc
      541 taggctataa ttatgattga taagaagtat cattccaagt attgagagtg aatgtttcaa
      601 aatcatgggt ttctataatg gtcaggctgg catttgctag accgccatct ttacgaagaa
      661 gtggttcttt atagcctagg agagtacgaa gactggcagt aagattggcg ccgtgtccga
      721 caattagaat acgctcagct ggactatctt ttaatgattt gataaattgg atggtccgct
      781 gagttgtact atagagggat tcggctccga acattcgagt gtcaaattga gcaagatttg
      841 aacgaaaagc ctggatttgt tgcgggtaaa tagcttccag ggttgcaatt ttcaaacctt
      901 ctaacttccc aagttgccat tcacggagat taggaacgat ttctaaagaa cagggggtat
      961 ggagttgact ttggataatc tcagcagatt tgaccgctcg aggtaaatca cttgaataaa
     1021 tctgatcaaa aggaatttcc ttgagatact gaccaagtcg ttttagggtt tcaatggatt
     1081 caggaagaag aggagaatca ccactagcac cttgaaaacg accttcttgg ttccagaggg
     1141 tacgaccgtg gcggacaaag tagagtttca ttacttgatg tcctccaaaa tatctacaaa
     1201 gtctgccttt acaaagctag ccaagtcttg tggcgcgacg ataatgctgt gtccgacttc
     1261 gcctgcagag acaatcattt gatccaaatc tagagcaatt ttatcgataa aaatgggata
     1321 attgtgtttc tgacgaattc cgacaggatt attggctcca tgaatgtaac cagttgtttt
     1381 ttctaagtac ttttgtggaa tcatgctcac ttttttattg ccagaaattt tagctagttt
     1441 cttttcagac aagtgctgag tgatagggac aattccgata atcggtccgg tcttgtctcc
     1501 caaaagcgcc aaggttttga aaatctgatc tcgttcataa ccttgaggaa gctctccttc
     1561 tagggcattg atttgaatcc cctgatgagg gatagctgat ttagatagga tttgttctac
     1621 caatgttttt ttgattttaa ctttttttgc cattatttat atttatcctc caattgactc
     1681 atccaaatac caagccagat tcccagcgca aagaagaagg cgatgatgac ataaccgaca
     1741 agtgaaagtc ctgtgtattg gatactttca gcgtttcctg catttggaat taagatcaaa
     1801 agggtacttg ataggacgat accgatgatg aaatgataga cgcgtgagtg gtagttgttt
     1861 aaggcataat ccatcaattt tgaaaaaacg atgagagttg cacctgcacc aattccaatc
     1921 ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag tcaacatagg agcatagagt
     1981 cccaaaatca aaagtaaatt cgatgggctg aggccaggaa ccaagacgcc aagggccaat
     2041 agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta aggttccaac gacaaaattt
     2101 aaggcataga gtcctaatcc agaaatgata aaggttgtcc ataaccaagc taaatcaatc
     2161 ttgtctcggt cagattctcg agttgattct ttgaggaggc taggaactgt accgataata
     2221 gctcccgcaa agctccataa tacaaagacc tgataatttt caagtaggta ttcaatcggg
     2281 taggaaaata agccgattcc tagaagcata ccgatggcaa ctggaataaa gtacaaaaca
     2341 ttttctttaa ggtctttaaa gggatgggcc agaaagccaa tcattcgttc atagattcct
     2401 aagattgctg ctagaacccc tccggaaatt cccggtagga taaatccaag agcaattaca
     2461 atccctttaa taacgcgtgc taaccatgag agcatatatt tcctccaact atttctattt
     2521 caaaaaatcc ttactatatt gtatcacaat cagacacaaa aagaaaaagc aaatgataaa
     2581 caaatgcttt taaggtttta aaaaaagctt tcgaaaggtt ttttctttat tttttaaggg
     2641 agagataacg ttgatatcta aatcgtggtc aaagccagca atttttcctt tagatgtgta
     2701 ttggtgaata tcataatcta aatcagtttt aggactgctc tccaaaaatc ctgagtctga
     2761 gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta tcaatactgt gttcttccat
     2821 gaagtagaca ccaacgtaga tgccgatgtt tttagcacct agtgatgcta gttttgctcg
     2881 aaagttttcg acaccttcgt tcatattaga catggttttg tcttccacgt caagccaata
     2941 gtaactaggg ctgtaaggag aggcagcatt gtagaaaact tcggcagcct tttccatttc
     3001 ttgggcactt tttccagcta cataagcgta gacagcaact gggacattcc gcttttgaag
     3061 ttcagtgata tgactcttat aggccttgtc tattccattg ataaatgaag catcattttc
     3121 ttttgtcgtt tgagcaccac tgtgaacacg aacaatagca cctgaaatat tttgtgagag
     3181 ggcatcgtag ttgatttcct caggacgctg ccagccagag aggtcaataa tcggtttgtc
     3241 taagtgtttc aaagcctgtg cttcaatctg tgctatattg gattttgttt taaacgattg
     3301 gttgtcatta agtgggcgat tgatgattaa aatgaacatc ataatcccca aaaaactaaa
     3361 taaaataagt ggatgaattt gttttctcat atcttataat tctaccctaa aaatcaaaaa
     3421 aaatcaaaaa aatgggttaa ggaagagact ttagagcatt ttttcattca agagtgcgga
     3481 atgatttgaa atatggtata ataaaaggga atttctacag aaaagagaag attatgtcaa
     3541 attttgccat tattttagca gcgggtaaag ggactcgcat gaaatctgat ttgccaaaag
     3601 ttttgcacaa ggttgcgggt atttctatgt tggaacatgt tttccgtagt gtgggagcta
     3661 tccaacctga aaagacagta acagttgtag gacacaaggc agaattggtt gaggaggtct
     3721 tggctggaca gacagaattt gtgactcaat ctgaacagtt gggaactggt catgcagtta
     3781 tgatgacaga gcctatctta gaaggtttgt caggacacac cttggtcatt gcaggagata
     3841 ctcctttaat cactggtgaa agcttgaaaa acttgattga tttccatatc aatcataaaa
     3901 atgtggccac tatcttgact gctgaaacgg ataatccttt tggctatgga cgaattgttc
     3961 gtaatgacaa tgctgaggtt cttcgtattg ttgagcagaa ggatgctaca gattttgaaa
     4021 agcaaatcaa ggaaatcaac actggaacat acgtctttga caacgagcgt ttgtttgagg
     4081 ctttgaaaaa tatcaatacc aataacgctc aaggcgaata ctatattaca gacgtcattg
     4141 gtattttccg tgaaactggt gaaaaagttg gcgcttatac tttgaaagat tttgatgaaa
     4201 gtcttggggt aaatgaccgt gtggcgcttg cgacagctga gtcagttatg cgtcgtcgca
     4261 tcaatcataa acacatggtc aacggtgtta gctttgtcaa tccagaagca acttatatcg
     4321 atattgatgt tgagattgct tcggaagttc aaatcgaagc caatgttacc ttgaaagggc
     4381 aaacgaaaat tggtgctgag actgttttga caaacggtac ttatgtagtg gacagcacta
     4441 tcggagcagg agcggtcatt accaattcta tgattgagga aagtagtgtt gcagacggtg
     4501 tgacagtcgg tccttatgct cacattcgtc caaattcaag tctgggtgcc caagttcata
     4561 ttggtaactt tgttgaggtg aaaggatctt caatcggtga gaataccaag gctggtcatt
     4621 tgacttatat cggaaactgt gaagtgggaa gcaacgttaa tttcggtgct ggaactatta
     4681 cagtcaacta tgacggcaaa aacaaataca agacagtcat tggagacaat gtctttgttg
     4741 gttcaaattc aaccattatt gcaccagtag aacttggtga caattccctc gttggtgctg
     4801 gttcaactat tactaaagac gtgccagcag atgctattgc tattggtcgc ggtcgtcaga
     4861 tcaataaaga cgaatatgca acacgtcttc ctcatcatcc taagaaccag taggagccta
     4921 tcatggagtt tgaagaaaaa acgcttagcc gaaaagaaat ctatcaagga ccaatattta
     4981 aactggtcca agatcaggtt gaattaccag aaggcaaggg aactgcccaa cgggatttga
     5041 ttttccacaa tggggctgtc tgtgttttag cagtaacgga tgaacaaaaa cttatcttgg
     5101 tcaagcagta ccgcaaagct atcgaggctg tctcttacga aattccagcc ggaaaattgg
     5161 aagtaggaga aaacacagcc cctgtggcag ctgcccttcg tgaattagag gaagaaacag
     5221 cctatacagg gaaattagaa ctcttgtacg atttttattc agctattggc ttttgtaatg
     5281 agaagttaaa actatattta gcaagcgatt tgacaaaagt ggaaaatccg cgtccgcagg
     5341 atgaggatga aaccttggaa gtccttgaag tgagcttaga agaagcgaaa gaattaatcc
     5401 aatcaggtca tatttgtgat gccaagacaa ttatggctgt tcagtattgg gagttgcaga
     5461 aaaaatagag gaggtcagta tgggtaaatc tttattaacg gatgaaatga ttgaaagagc
     5521 taatagaggc gaaaaaattt caggtcctcc tttgctagat gataatgagg aaactaagat
     5581 tttaccaacc tcttcttccc gttttggtta tgccaatcct aaggatcatg gttttagcca
     5641 ggaaaccttg aagattcagg tcgaaccatc tattcataaa agccgtcgta ttgaaaatac
     5701 caagagaaat gtcttcaatt ctaagttgaa taaaatctta tttgcggtca tctttctctt
     5761 gattttgctt gttttagcaa tgaaactttt gtaatagaaa aggaattgaa atgaaaatag
     5821 gaattattgc tgctatgcca gaagaactgg cttatctggt ccagcattta gataatgccc
     5881 aggagcaagt tgttttgggg aatacctatc atacaggaac cattgcttct catgaagtcg
     5941 ttcttgtaga aagtggaatt ggtaaggtca tgtctgctat gagtgtggcg attttggctg
     6001 atcatttcca ggtggatgcc cttattaata cgggttcagc tggggcagta gcagaaggta
     6061 tcgctgttgg ggatgtcgtg attgctgaca aattagccta tcatgacgtg gatgtcacag
     6121 cttttggcta tgcttatgga caaatggcgc aacaaccgct ttatttcgaa tcagacaaaa
     6181 cctttgttgc tcaaatccaa gagagtttat ctcaattgga ccaaaactgg catcttggtt
     6241 tgattgctac aggagatagt tttgttgcag gaaatgacaa gatagaagcg attaagtccc
     6301 atttcccaga agttttagcc gtggagatgg agggggcagc tattgctcaa gcagcgcatg
     6361 ccctcaatct cccagtctta gtcatcagag ctatgagtga caatgccaac catgaagcaa
     6421 acatcttttt tgatgagttt attatcgaag ctggacgtcg ctctgcccaa gtcttgttga
     6481 cctttttgaa ggctttagat taagcggaaa tttgacagtt tttctagctt atgataagat
     6541 ttaagtaaag aaaagctaga aaacgtttca gaggatatta tgagtattga aatgaccgtc
     6601 agtgagattg cagaggtctt aggattatct cgccaagcaa tcaataaccg tgtcaaagaa
     6661 ttaccagaag aagacacaga taaaaatgac aaaggggtaa cagttgttac cagaagtggc
     6721 ttgattaagc tagaagaaat ctataaaaaa acgatttttg aagatgagcc tgtcagtgaa
     6781 gatgtcaaac aacgtgaact gatggagatt ctagtggatg agaagaatgc agaaattctt
     6841 cgtctttatg aacaattaaa agccaaggat cgtcagttat cagaaaaaga cgagcagatg
     6901 cgtatcaaag accgtcagat tgctgagaaa gacaaacaat tagatcagca acaacaattg
     6961 acccttcaag ccatgaagga tcaagaaaat cttaagctag agctggacca agcaaaagaa
     7021 gaagtccaat ccactaagaa aggctttttt gctcgtttat ttggaggata atcaaggagc
     7081 tgtttaggtt aaatgctaac ctgatggctt cttttgtttg tgaatagtat agttgattag
     7141 aacagagaca gtagaggaga ggtacagaat ggaacgatta gaagattaca ttgcttttga
     7201 tttagaattt aatcagcacg aaggacaaac acacttgatt caagtatcgg cagtgcgttt
     7261 tagagatggt cgggaaatcg atgcctatga ttcctatgtt cataccagcg tccctctaaa
     7321 aagctttatc aatggtttga ccgggattac agctgagacc ttaaaagatg ctcctccagt
     7381 tgagaaagtc ttagaagaat tccaagagtt tgtgggttct ttgctgatga taggctacaa
     7441 tgctgctaaa agtgatttac ctattttagc agagcatggt ttagactata gccaacagta
     7501 caaggtggat ttgtatgatg aagcttttga acgtcggagt tcagatttac atggtattgc
     7561 caatctcaaa ttgcaaactg ttgcctcatt tcttggattt caaggtcagt ctcataatag
     7621 tttagaggat gctcggatga cggcgcgtgt ttacgaatcc ttcttagagt cggatcaagc
     7681 tagggaattg ttagagacag aaagtagctt atcaaacaat ccttttggtg gcttggactt
     7741 gtctcaatta tttgactagg agtgcctatg aaacctgaaa aacctaaaaa attgggtctt
     7801 aaacagattt acctcaatct tgataaaatc ctctttctat ttttcttgat ttttatgata
     7861 gtggagtatt tgtgggtacc attcaattca tggttggcta gcttcttatt agatcagaca
     7921 ggttatcttt ttatttccta taacaatgtc ttagccatcc ttactcattc tccattgatt
     7981 agtctagctt ttttagcctt gattgtaatt aaccttctgg ttgcttattt tcaaatagga
     8041 ctcctcttta ttggtgctcg tcatctcctc tataatgaaa agcgaaggct aattgagtat
     8101 atccgcaagg ttttccatga aagttttgga tttatgaaaa agctaacttg cgctaaagcc
     8161 ttgtttatct ttttctatat agctatgctt tttcctttta tacggaaaat gttgaagatt
     8221 tattatctta ataaaatcgt cattccagag tttatccaag cttatttaga agataaatat
     8281 tggatgtggt ggctgagcat cctacttcta tctcttatct ttctctatgt ctctgtcaga
     8341 ttgatgtttg cccttccgaa gattgtatat gatcagctga ctgttcgaga agcagtgatg
     8401 tttagcttgg agaaaaccaa gaagagagtt actttttatg cttggaattt attttacatc
     8461 ttgctcaaag cacatttatt attttatctt cctttgatcc ctttattatt ggctcaaact
     8521 ttggtagatg atatcactca gagagagtct ctgattcttg gtattttgaa ttttgtcgtg
     8581 attaaaaatc tctattatat ggctctgact tattttttgg ttaaatttgt ttcatttttg
     8641 acaggaaagg agctggatat gcttcctagg agagaaaaag atcacatcgt gcgatggggt
     8701 gtcatgactt gtgccagtct tttctttgcc ttagaaggtt atatttatct ggaggctccc
     8761 atggttcatc tacctcaact tatttctcac cgaggggttt ccaatgcaaa tgggattcaa
     8821 aatacagtag agtccttgga aactacagca caactcaaac cagacttggt ggagacggac
     8881 gtgcaggaaa caaaagatgg gcagtttgtc atgatgcatg atgctaactt gaaaaatcta
     8941 gcaggtatca ataaaagtcc tcaagactta aacttggagg agcttaaagg gattgatatt
     9001 tttgaaaatg gctaccagac taaaatttca agctttgaag attatctcag tcgagccaac
     9061 gaacttggtc aaaaattact aattgaaatt aaaaccagta aaaaagatag tccagacatg
     9121 atgaaccgct ttttagcccg ttatgctgca aagctcaaga tttatggaca tcaaatccag
     9181 tctttagact accatgttgt cgaaaaagta agacagtatg atgccgaact gccagtttat
     9241 ttcatcatgc cctacaattc tgtctttcct aaaacaagag cgacaggata tactatggag
     9301 tactcaacct tggatgaata ttttgtaagc aaactatgga caacggatca gaaactttat
     9361 gtctggactg tcaatgattc agaagctatc agcaaatctc ttcacttagg agtagatgga
     9421 gtgattacag atgatttgga aaaagttcag cgggaaatag aagtagccca agaagatcca
     9481 gaatatacgg atttgctctt gaaaaaagca ttggaattct ttgaatttta gtaataaaaa
     9541 agaggaacgg ttgttcctcc catgataggt aagtattctt gtgaatgctt gcttttttgt
     9601 ggttgcaatc cgtttacgag aattgtttgt attgttcttg tttcaattta ctttatagtg
     9661 ctttgaagtt ggaatgctac actataactt ataaaatata gt
//
LOCUS       DAVKZI010000061         9575 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKZI010000061 DAVKZI010000000
VERSION     DAVKZI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.062"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            10..873
                     /locus_tag="VXB18_001962"
     CDS             10..873
                     /locus_tag="VXB18_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0383109.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1256..1876
                     /locus_tag="VXB18_001963"
     CDS             1256..1876
                     /locus_tag="VXB18_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383110.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            1962..2405
                     /gene="tsaE"
                     /locus_tag="VXB18_001964"
     CDS             1962..2405
                     /gene="tsaE"
                     /locus_tag="VXB18_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0383111.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2395..2913
                     /locus_tag="VXB18_001965"
     CDS             2395..2913
                     /locus_tag="VXB18_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0383112.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2921..3937
                     /locus_tag="VXB18_001966"
     CDS             2921..3937
                     /locus_tag="VXB18_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0383113.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4021..5277
                     /locus_tag="VXB18_001967"
     CDS             4021..5277
                     /locus_tag="VXB18_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0383114.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5332..6498
                     /gene="recA"
                     /locus_tag="VXB18_001968"
     CDS             5332..6498
                     /gene="recA"
                     /locus_tag="VXB18_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0383115.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6805..8175
                     /locus_tag="VXB18_001969"
     CDS             6805..8175
                     /locus_tag="VXB18_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0383116.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8551..9507
                     /gene="lytA"
                     /locus_tag="VXB18_001970"
     CDS             8551..9507
                     /gene="lytA"
                     /locus_tag="VXB18_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0383117.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
BASE COUNT         2917 a         1648 c         2137 g         2873 t
ORIGIN      
        1 ttatctttaa tgaatacact cgcagagaaa ttcagattga aaagaaaaga gttgagactc
       61 tcccaacaaa ctcttgcaga aggaatttgt gaacaaagcc agattagtaa aattgagaga
      121 gggcatttca ttccctccgc agaccttttg ttcaaactct ctcaacgact tgaagtacca
      181 ttagattatt tttttaatga acaaattgaa attaaatcta acctctctaa tttcaagcaa
      241 ttgtctgctc gactattaga cgatagaaat tatgacgatt tggaatatat ttatagaata
      301 gagattgaac gaagtacttt tctaacacta gaagaccgaa cttaccttga atggattaaa
      361 gctattattg acttctatca atatgacagt aagtgtgagg caatttcttc attggaaaat
      421 atattattaa aagtctcttc aaatactctg atttatttaa aggcgttgaa tactctatct
      481 aatttctatt ccttagtggg tcgtgaacaa gaatatgagg caaactactc tcatttaata
      541 gagttgtatc agacaaaaaa tttggaccat caagagtttt tatttggcta catcagagtt
      601 cgttacaact acgctcacta cctagtatca aaggaaaaat ataatgaagc catccaagaa
      661 gctcttgaaa cgattgaact ctgtaaacaa agacagacaa gctaccaatt ggctcctcta
      721 cttattcttg taggaaatgc tggagccaaa tttctagaca gagaacaagt caaaaattat
      781 tatatagaag caagagagct atgcaagatt tataacaatc ctttaatgct gatgaagata
      841 gaaaattatt tgaaggaact agatactgtt tagttaatct tgacattata gtttttctga
      901 aacgttaaat aacctgtaag gctgatagtt agattaatac tatcagcctt ataattatgt
      961 gactctgagt ccgtctcgct ccgtgaggtg cgagacaaaa caaccacccg tttgacggat
     1021 tttcatgatt tcaaatctat attcttcgaa aatctcttca aatcacgtca gctctatctg
     1081 caatctcaaa acactgtttt gagcaacctg tggctagcta cctagtttga tctttgattt
     1141 tcattgagta ttagtctcta gtgtttgttt agcgtcttaa agagacattt gagaagatta
     1201 gaaacagttc tctcttttct cctagtataa tgattggtag gaagggagag agaagatgaa
     1261 atcaatgaga atcttatttt tgttagcttt aattcaaatc agtttgagta gctgtttcct
     1321 atggaaggaa tgcatcttgt cctttaaaca aagtacagct tttttcatcg gaagcatggt
     1381 tttcgtttca ggaatctgtg ctggagtaaa ttatctttat acccgtaagc aagaagtcca
     1441 tagtgtccta gccagtaaga agtcggtgaa gcttttttac agtatgttac tcttaattaa
     1501 tttgttagga gctgttcttg ttttgtcaga taacttgttc atcaaaaata cgctgcagca
     1561 agaattagtt gactttttat tgccatcctt ctttttccta tttgggctag atttgctgat
     1621 ttttttaccc ttgaaaaaat acgtgcgcga ttttcttgct atgctagaca gaaaaaagac
     1681 agtgttggtg actattttag caacacttct tttcttaaga aatccaatga ccattgtctc
     1741 acttctgatt tatattggac tgggcttgtt ttttgcagcc tatcttgtcc caaattcggt
     1801 taagaaggaa gtttcctttt atggtcatat tttccgagat cttgtattgg tcattgttac
     1861 gctcattttc ttttagagaa agcctgtttt ttatggatgt tatgatgata agtttagtag
     1921 gaaaatagac acaaaagaaa agtttttggt ataataagag tatgtacaca aaaaatgaag
     1981 aagagttgca agccttaggg gagcgtttgg gccatctatt agcaaagaat gatgttttaa
     2041 tcttaactgg agaactgggt gcaggtaaaa cgacctttac taaaggactt gcaaaaggat
     2101 tacagatttc tcaaatgatt aaaagtccca cctatactat cgtgagagag tatgaaggtc
     2161 gacttccact ttatcaccta gatgtttatc gtattgaagg agatgctgat tctatcgact
     2221 tggatgagtt tatctttggt ggtggcgtga ctgttattga gtggggaaat ctcttaggag
     2281 atgccttgcc agatgcttat ttagaattgg aaattctaaa agaagcagat ggacgccgtt
     2341 taaattttca ggcaaagggt ttgcgtgctg agaaattgtt agaggagctt caatatggag
     2401 tatgaattgc tcattaggga agcagagccc aaagatgcag ctgaattagt ggccttttta
     2461 aatcgtgtga gtttggagac agactttacc agcctagacg gagatggtat tctcttgact
     2521 agtgaggaga tggaaatatt cctcaacaag caagctagtt cggacaatca gataacctta
     2581 cttgcattct taaatggcaa aattgctggt attgtaaata ttacagctga tcagcgtaag
     2641 agagtccgtc atattggaga tctcttcatt gtgattggaa aaagatattg gaataatggc
     2701 ttgggaagtt tgttgctaga agaagcgata gagtgggcac aagcaagtgg cattctgcgt
     2761 cgtctccaac tgactgtcca aactcgtaat caagcagcag tccatcttta tcaaaagcat
     2821 ggctttgtca ttgaaggtag ccaagagcgt ggggcatata tagaagaagg gaaatttatc
     2881 gatgtttact tgatgggtaa actgataggt tagtagaaat atggttaaaa aaattattgg
     2941 aatggtgcta gctttacttt ctgtaactgt agtaggagta ggtgtttttg cttatactat
     3001 ttatcaacaa gggacagaaa ccttagctaa aacctataaa aaaatcggcg aagaaaccaa
     3061 ggttattgaa gcgactgaac ctctaaccat tctgttaatg ggagtggaca ccggaaatgt
     3121 tgaacgaact gaaacttggg tcggtagaag tgatagcatg atcttgatga cagtgaatcc
     3181 taaaacgaaa aaaacaacaa tgatgagttt agagcgggat attctgacgc gcattgaatc
     3241 agggaatggt caggctcatg aagcgaaact gaactcagca tatgcagatg gtggagcaga
     3301 gcttgctata gaaaccattc aaaaaatgat gaatatccat attgatcgct atgtgatggt
     3361 caatatgaga gggttgcaaa aactagtgga tgcagtagga ggtattacag tcaataatat
     3421 cctaggtttc ccaatttcta tcagtgacca agaagaattt aatactattt ctatcggtgt
     3481 tggggagcaa catattgggg gagaagaagc cctagtctat gcacgaatgc gttaccaaga
     3541 tcctgagggg gattatggtc gtcaaaaacg tcaacgtgaa gttattcaaa aagtcatgga
     3601 aaaagctctc agtttaaata gcattggtca ttatcaagag attttaaaag ctttgagtga
     3661 caatatgcag accaatattg atttgtctgc aaaaagtatc cctaacttgc taggctataa
     3721 agattcattt aaaaccattg aaactcagca gttgcagggt gaaggagaga tacttcaagg
     3781 tgtttcttac cagattgttt cgagagcaca tatgttggaa atgcaaaata tactccgacg
     3841 ttctttggga caagaagaag ttactcagct tgaaaccaat gcggttttat ttgaagattt
     3901 atttggcaga gcacctgttg gtgatgaaga taattaactt ttgatacaaa taaaaaatca
     3961 atcgtaggaa aattcctgcg attttttcaa aaaaatacga atagataggt aggaggaaac
     4021 atgaaagcag aaatcattgc tgttggaaca gagattttga caggacagat tgtcaacacc
     4081 aatgcccagt ttttgtcgga aaaactagct gagattgggg tagatgtata ttttcagacg
     4141 gctgtaggag acaatgaagt tcgtctcttg tctttgcttg agattgccag tcaacgtagc
     4201 agtctggtga ttttgacagg cggtttgggg ccaactgagg acgacctaac caaacaaacc
     4261 ctagctaaat ttttagggaa agcattagtc tttgatcctc aggctcagga gaagttggat
     4321 atcttttttg ccctgcgacc agactatgcc cgaacaccga ataacgaaag acaagctcaa
     4381 attgtagaag gagcgattcc actgccaaac gaaacaggac tggctgttgg aggaaaatta
     4441 gaagtagacg gagtgaccta tgtcgtcctt ccaggtccgc caagtgaatt gaaacccatg
     4501 gtcttaaacc aacttctacc caagttgatg acagggagca agctgtattc ccgagttctt
     4561 cgtttctttg ggattggcga gagccagttg gttacgattt tggctgattt aattgataat
     4621 cagatcgatc ctaccttggc cccttatgcc aagacaggag aagtcactct acgtctgtca
     4681 acaaaggcta gcagtcaaga agaggcgaat caagcgctgg atatcttgga aaatcaaatc
     4741 ttggactgcc agactttcga aggaatttct ttacgagact tttgctatgg ttatggggaa
     4801 gaaactagtt tagccagcat tgtggtagaa gaactgaaaa ggcaagggaa aaccatcgcg
     4861 gctgcagaga gtttgacggc aggtcttttc caagctaccg tggcgaattt ttctggagtt
     4921 tcaagtatat ttaagggtgg ttttgtgacc tatagcttgg aggaaaaatc aaggatgttg
     4981 gatattcctg ccaagaattt ggaagaacat ggtgtggtgt ctgaatttac agctcagaag
     5041 atggctgagc aggcacgaag caagacccag tctgattttg gaattagttt gactggagtg
     5101 gcaggaccag atagcctaga aggacaccca gttgggacag tcttcatagg cttggcgcaa
     5161 gatcaaggaa ctgaagttat caaggttaat attggaggca gaagccgagc agatgtacgt
     5221 cacattgcgg ttatgcatgc ctttaaccta gttcgcaagg ctttattaag tgactaactt
     5281 ttgatataat agtagatagg tctgaggatc attagaatgt aggagaatag aatggcgaaa
     5341 aaaccaaaaa aattagaaga aatttcaaaa aaatttgggg cagaacgtga aaaggccttg
     5401 aatgacgctc ttaaattgat tgagaaagac tttggtaaag gatcaatcat gcgtttgggt
     5461 gaacgtgcgg agcaaaaggt gcaagtgatg agctcaggtt ctttagctct tgacattgcc
     5521 cttggctcag gtggttatcc taagggacgt atcatcgaaa tctatggccc agagtcatct
     5581 ggtaagacaa cggttgccct tcatgcagtt gcacaagcgc aaaaagaagg tgggattgct
     5641 gcctttatcg atgcggaaca tgcccttgat ccagcttatg ctgcggccct tggtgtcaat
     5701 attgacgaat tgctcttgtc tcaaccagac tcaggagagc aaggtcttga aattgcggga
     5761 aaattgattg actcaggtgc agttgatctt gtcgtagtcg actcagttgc tgcccttgtt
     5821 cctcgtgcgg aaattgatgg agatatcgga gatagccatg ttggtttgca ggctcgtatg
     5881 atgagccagg ccatgcgtaa acttggcgcc tctatcaata aaaccaaaac aattgccatt
     5941 tttatcaacc aattgcgtga aaaagttgga gtgatgtttg gaaatccaga aacaacaccg
     6001 ggcggacgtg ctttgaaatt ctatgcttca gtccgcttgg atgttcgtgg taatacacaa
     6061 attaagggaa ctggtgacca aaaagaaacc aatgtcggta aagaaactaa gattaaggtt
     6121 gtaaaaaata aggtagctcc accgtttaag gaagccgtag ttgaaattat gtacggagaa
     6181 ggaatttcta agactggtga gcttttgaag attgcaagcg atttggatat tatcaaaaaa
     6241 gcaggggctt ggtattctta caaagatgaa aaaattgggc aaggttctga gaatgctaag
     6301 aaatacttgg cagagcaccc agaaatcttt gatgaaattg ataagcaagt ccgttctaaa
     6361 tttggcttga ttgatggaga agaagtttca gaacaagata ctgaaaacaa aaaagatgag
     6421 ccaaagaaag aagaagcagt gaatgaagaa gttacgcttg acttaggcga tgaacttgaa
     6481 atcgaaattg aagaataagc tgttaaagca gtggaaaaat ccgctacttt ttcgattttt
     6541 gattcaagtt tttagattat atatagtagc ttgaaataag atatgaacaa ctttattagg
     6601 aaagtcaaat taatttctag aaatgtttta gcagctacag cgtactattc caaactcaac
     6661 caactataat agatcgaaac tagaatagta cacatctact tctaaaacat tgttaaaaat
     6721 cgatttgact gtccttattt cattccgcta tatataagtt tgctgtttct tgtcgctcct
     6781 ctggaaagct gatataatag ctttatgaat aaaaaacgaa cagtggacct gatacatggt
     6841 tcgattcttc cctcgctctt aagcttcacc tttccaatct tgctatcaaa tatttttcaa
     6901 cagctctata acactgctga tgtcttgatt gttggacgat ttcttggtca agaatccttg
     6961 gctgcagtag gagcgacgac agcgattttt gacctgattg taggttttac acttggtgtt
     7021 ggcaatggca tggggattgt cattgctcgt tattatgggg ctcggaattt cactaaaatc
     7081 aaggaagcag tagcagccac ctggatttta ggtgctcttt tgagcattct agttatgttg
     7141 ctgggctttc ttggcttgta tcctctcttg caatacttag atactcctgc agaaattctt
     7201 cctcaatctt atcaatatat ttctatgatt gtgacctgtg taggtgtcag ctttgcttat
     7261 aatctttttg caggcttgtt gcggtctatt ggtgacagtc tagcagccct gggatttctg
     7321 attttctctg ccttggttaa tgtggttctg gatctctatt ttattacgca attgcatctg
     7381 ggagttcaat ccgcaggact tgctaccatt atttcgcaag gtttatcagc ggttctctgc
     7441 ttttattata ttcgtaaaag tgtgccagaa ctcttgccac ggtttaaaca tttcaaatgg
     7501 gacaaaagct tgtacgcgga tctcttggag caaggtttgg ctatgggctt gatgagttca
     7561 attgtatcta tcggcagtgt gattttacag ttttctgtta atacatttgg tgcagtgatt
     7621 attagtgccc agacggcagc tcgacgcatt atgacctttg cccttcttcc tatgaccgct
     7681 atttctgcat caatgacgac ctttgcttct cagaatctag gagctaagcg acctgaccgc
     7741 attgttcaag gtcttcgaat cggcagtcgt ttaagtatat cctgggcagt ttttgtttgt
     7801 attttcctct tttttgccag tccagccttg gtttccttct tggctagttc gacagatggt
     7861 tacttgatag aaaatggaag tctctatctg caaatcagtt cagcctttta tcccattttg
     7921 agcctcttgt tgatttatcg caattgcttg cagggcttgg ggcagaagat ccttcctcta
     7981 gtttctagct ttattgaact aatcggaaaa atcgtttttg tggttttgat tattccttgg
     8041 gcaggatata agggtgttat cctttgtgaa cctcttatct gggttgccat gacagttcaa
     8101 ctgtacttct cactattccg tcatcccttg ataaaagaag gaaaggcaat tttggcaacc
     8161 aaagtgcaat cctagttgga tttactgaat aaaattcatt tcctctagtg aacatcgaaa
     8221 aaacttgtgt tctcgtcttt agtttggtgt tgaaaatagt ttaacagact tttgacttct
     8281 tttatatgat ataataaagt atagtattta tgaaaaggac atatagagac tgtaaaaata
     8341 tacttttgaa aagcttttta gtctggggtg ttattgtaga tagaatgcag accttgtcag
     8401 tcctatttac agtgtcaaaa tagtgcgttt tgaggttcta tctacaagcc taatcgtgac
     8461 taagattgtc ttctttgtaa ggtagaaata aaggagtttc tggttctgga ttgtaaaaaa
     8521 tgagttgttt taattgataa ggagtagaat atggaaatta atgtgagtaa attaagaaca
     8581 gatttgcctc aagtcggcgt gcaaccatat aggcaagtac acgcacactc aactgggaat
     8641 ccgcattcaa ccgtacagaa tgaagcggat tatcactggc ggaaagaccc agaattaggt
     8701 tttttctcgc acattgttgg gaacggttgc atcatgcagg taggacctgt tgataatggt
     8761 gcctgggacg ttgggggcgg ttggaatgct gagacctatg cagcggttga actgattgaa
     8821 agccattcaa ccaaagaaga gttcatgacg gactaccgcc tttatatcga actcttacgc
     8881 aatctagcag atgaagcagg tttgccgaaa acgcttgata cagggagttt agctggaatt
     8941 aaaacgcacg agtattgcac gaataaccaa ccaaacaacc actcagacca cgttgaccct
     9001 tatccatatc ttgctaaatg gggcattagc cgtgagcagt ttaagcatga tattgagaac
     9061 ggcttgacga ttgaaacagg ctggcagaag aatgacactg gctactggta cgtacattca
     9121 gacggctctt atccaaaaga caagtttgag aaaatcaatg gcacttggta ctactttgac
     9181 agttcaggct atatgcttgc agaccgctgg aggaagcaca cagacggcaa ctggtactgg
     9241 ttcgacaact caggcgaaat ggctacaggc tggaagaaaa ttgctgataa gtggtactat
     9301 ttcaacgaag aaggtgccat gaagacaggc tgggtcaagt acaaggacac ttggtactac
     9361 ttagacgcta aagaaggcgc catggtatca aatgccttta tccagtcagc ggacggaaca
     9421 ggctggtact acctcaaacc agacggaaca ctggcagaca agccagaatt cacagtagag
     9481 ccagatggct tgattacagt aaaataataa tggaatgtct ttcaaatcag aacagcgcat
     9541 attattaggt cttgaaaaag cttaatagta tgcgt
//
LOCUS       DAVKZI010000062         8779 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKZI010000062 DAVKZI010000000
VERSION     DAVKZI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.063"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            61..747
                     /locus_tag="VXB18_001971"
     CDS             61..747
                     /locus_tag="VXB18_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0383118.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            748..1680
                     /locus_tag="VXB18_001972"
     CDS             748..1680
                     /locus_tag="VXB18_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0383119.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1691..2620
                     /locus_tag="VXB18_001973"
     CDS             1691..2620
                     /locus_tag="VXB18_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0383120.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2634..4073
                     /locus_tag="VXB18_001974"
     CDS             2634..4073
                     /locus_tag="VXB18_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383121.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4142..5719
                     /locus_tag="VXB18_001975"
     CDS             4142..5719
                     /locus_tag="VXB18_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0383122.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5779..7239
                     /locus_tag="VXB18_001976"
     CDS             5779..7239
                     /locus_tag="VXB18_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0383123.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNIEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPI
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7261..7716
                     /locus_tag="VXB18_001977"
     CDS             7261..7716
                     /locus_tag="VXB18_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEV0383124.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7803..8209
                     /gene="cdd"
                     /locus_tag="VXB18_001978"
                     /pseudo
     CDS             7803..8209
                     /gene="cdd"
                     /locus_tag="VXB18_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8222..8671
                     /locus_tag="VXB18_001979"
     CDS             8222..8671
                     /locus_tag="VXB18_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0383125.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKVKI"
BASE COUNT         3058 a         1136 c         1652 g         2933 t
ORIGIN      
        1 taaaattgta gtagatgtta ttgaattagt aaaaaaaata aaaaaacgga ggttttctga
       61 atggaaacta aaaaaattaa aaatttaaaa ggtcaaataa ttgtttcctg ccaagcgtta
      121 gaaggagagc cactttatac tccaaatgga ggagtgatgc cgttattagc aaaagccgcc
      181 tttcaagcag gcgctaaagg tattcgtgct aattctgtcc gcgatatttc agaaataaaa
      241 gaagaagttg acttaccaat tataggtatc ataaaaagag attacgatgg ctttgaacct
      301 tttatttcag caactatgaa agagattgat gaattagtta gtgaaggagt agacatttta
      361 gctttggatt gtactaatcg ttcaagacca ggttatgata atattactga ctttattcat
      421 gatattaaag tcaagtatcc aaaccaatta ttaatggctg atatttctac ttttgaagaa
      481 gggaaagtag ctgctgaatc gggagtagat tttgtgggta cgacattatc tggttataca
      541 ccatatagcc ctaaaaaaga taatcctgat tttgagttag ttgaaagatt ggtaaaagag
      601 cttgacgtac cagttattgc tgaaggaaga ataagtactc cggaacaagc tagaaaaatg
      661 ttagatttag gtgcttacgc agtggttgtt ggaggagcta tcactcgtcc tttggaaata
      721 gcgaagaagt ttattgaggt agtttagatg aatcaagaaa tattaaaaaa gagtaagatt
      781 caattgacag ttgaacatat tcaaaaatat tggattttat atttaatgat gattccagca
      841 actgttctac taattttatt tacgtatgga ccaatgtacg gcattattat ggcctttcaa
      901 gactttactg tcttcaaggg atatactgga agtccatttg tcggtttaaa acattttcaa
      961 agattgttct cagatccttt gttttataga ttgttcaaga atacgttcat ggtaggggtt
     1021 ttagactttt tattctcttt cccagctccg cttatttttg cactcatatt aaacgaagtc
     1081 agaaaagtaa gatttaagag tgtagttcaa tctattagtt atcttcctca ttttattccc
     1141 ctagtggtta tggttggtat tatttttgaa ctatttggtt catatggtat tattaacagt
     1201 ttactttcat cacttggaat ggagccaata agtttcttta caaaatctga atggttcttg
     1261 cctctctaca ttggttcagg agtatggaaa acaataggtt ggggttctat catttatatg
     1321 ggagcattaa ccaatataga ttcaacttta tatgaagcag cagatatgga cggggctaat
     1381 agatggcaca aaatgtggca tgtaactcta ccaagtttaa gacctacagt agttactttg
     1441 tttatactaa atgctggtgg tatcatgcaa gtaggatttg aaaaggtatt cttgatgtct
     1501 agtcctgcaa catatgaagt atctgatgta ttatctactt atgtttatag acaaggtatt
     1561 ttaaattctg atttcagtta ctcagctgca gtaggattat ttaataacat agtagctttg
     1621 ttatttgttt tattagctaa taagattgct aaaaaacttg gcgaagaagg aattgtataa
     1681 ggggggtaaa atgatttttt caaaaaatac aaaaaagagt aatagagaca aagaaacctt
     1741 cgttgattat ctctttatat tcattttaat aataataacc ttacttatgt tgtatccatt
     1801 atggtgggta gtgatgacgt cactttcaga accagtttgg ctatctaaaa acgttgttaa
     1861 attatttccc ttaaaaatag atattactgc atataagttt atttttgggg attctaaact
     1921 atggcaagca tatggtaata gtgtattgta tgctgcacta tctacaattg ttagtgttgc
     1981 ggtatgtagt atgtatgcct atccacttac aattcctgaa attaggggta aaaaattctg
     2041 gaatactctt attttgattc caatgttctt tagtggagga atgatcccgc tttatataca
     2101 agttgcaaac ctcggtttat tgaatactgc ttgggctctt gttttacctg gtgctgtttc
     2161 tacatattat ataattttgt ttagaacaca gtttaaatca atcccaatgg agcttcgtga
     2221 gtctgctaga attgatgggg caagtgaatt tagaattttt tggaatttag tattaccatt
     2281 atcaaaagtt attttcatga ttatagcact ttattgcata gttggttcat ggaatagttt
     2341 tactcctcca ttactttatt tgaatgacga cactaagatg cctttatcta tttatttgag
     2401 aaatttagtt gttacaaata caactgatac tgctgaatta tcactttctg caggtaatac
     2461 atattaccaa caaattgctg ctcaaggtgg aggtattggt atgcgtattg ctattaagat
     2521 gggtactatt gttgttagtg ttattccaat tatgatgatt tatccattta ttcagaaaca
     2581 ttttgttaag ggaatcctgc taggttctgt gaaaggttaa taaggtaatt attttgcaaa
     2641 atttaaaaaa atatctttta ttagatagcg gtttagtagt tgggtataca ttagaaaatg
     2701 ctcaattaaa attaaataag ctaaaaaaag atactgaaaa caatccacta tttggtgaag
     2761 agtattttgc cgaaaatcct aaattatggg aagttcgttt tgataattca tatccaaacg
     2821 ttatctatga taaagaattg aaattatata gatgttggta tcaaacattt gttagtgatg
     2881 aagcaagcga agagactcct ttagcagaac gtggagagaa ggaatacatt gtcaagtcat
     2941 ctagaatgac agcactttgc tatgctgaaa gtaaagatgg agtaaaatgg gaaaaaccaa
     3001 atctcaatct agtaaaattt aaaggttcaa aagataataa tattgttctg atgcatgcac
     3061 acggtgcagg tatcatgcta gatgaacagg agttggatcc taagaaacga tataaattag
     3121 tttcaaaatt agaattttct ccgaatcttc attacatggt tgttgttttt tcagaagacg
     3181 gtattcattt tgacgaacct attccatgga aaaaatggaa tcctgcagca gatagtcata
     3241 attttccatt tagagatcca aaaactggta aatacgctgt tattacaaga acctgggcaa
     3301 ataacgtacg tctaagtgca attactttca gtgatgattt tattaattgg tcagaaccta
     3361 aagaaatcct taggggagat ggatttgaag atcaaattta ttctatgcca gtaatttcat
     3421 acgcggatat ctatttaggt tttgcttcaa tgtaccacga aggcgacact ttaaatgaaa
     3481 actatgataa agtagactta gaattgaaat tctctgctaa tttggaacaa tgggatagtg
     3541 tatgtaaggg cgactatctc attgaaaggg gaggtggagt atacccgcag aatgctgatt
     3601 ttgatgctag ttgtattttc acggctgctc caataattga agatgataag atttggttct
     3661 actatatggg tggaaatggt aatcacactg gcttccgaga aagttcatta gctagaggat
     3721 atattaagaa agaccaattt gcttattata ctaataagag agaaggaatt ccagctaaaa
     3781 tatctacagt tagcttccaa acttacgatg atgaaattta tatcttagct gatattcctg
     3841 aaaatggtta tattaaagtt gcggtaggta ctaaatacgg taatgcttat tcagattttg
     3901 gtcaggaaga tatctctctt gttcaagttt ccgatggtaa gtataagttg gaatttaata
     3961 aaaaatctat cttagattta ggtaattctc cagttgcgtt caaatttgaa atcgagaatg
     4021 caaaattgta tggtattgaa ggtagtattc agcaacacta tctcaaatat taaccagaat
     4081 aattcgttaa caaataatct ctatattagt ggagatagat atataaaatg gaggtcttat
     4141 tatggtaaag cttaataagg tattaaaagg gagtgttgca ttcctgagtg caagtttatt
     4201 gctagcagct tgtggcaata acgctaattc aaagcccgct gaaaaaacag ctgatggtaa
     4261 aacgaaaatt tcgtttctat ctacatggca aattaatgat gttcgtccgc ctaaagatga
     4321 aacacttgtt ggtcaatggt tagaagaaca gctaggtatt gatattgatc ttgtaactat
     4381 tcctggcgag ggagtaagtt ctaaagtaaa ttctcttatt actagtaacc agttaccgac
     4441 tgttttgttg acaacaggag ataagagtga tatcgctggt atcaacaaac ttggtaaaca
     4501 gggtgcattc ttagatttgt cacaacacat ggacaaacta ccaaactata agaagtacct
     4561 tgaaaaaaat aatgcattag ctcaaataga agatgatgaa aaacatattt atgctttcac
     4621 aaaattcttt actgatgaga atatcatgta tactacacca attctgagaa aagacttact
     4681 tgttggttca gaatttgaag atctttcaaa aattaaaact gttgatgact atacaaaagt
     4741 tttgaaatat ttgactgaaa aacaaggttc tccagcattt attcaacgta atggctatga
     4801 aggcttcatg aagcgagtta caccattgtg gaatttaagc catcgtacat actatgacta
     4861 tgaatcagat tcatataaac atccagttga acaacctcaa ttgaaacaat tcgttgaatg
     4921 gttgaaagaa ttacgtaaag ataacgtact tcaccctgac tgggcagtta tgaaagatga
     4981 aacttgggaa ggtctattgg cttctaacaa gggttcattc actgttgacc gtatgaatat
     5041 cattggagat aataactttg ataaatcatt tgattggcag ccacttgttt atccaaaaat
     5101 taatggaaaa cgttatttgc aaccgaaaac accgtacatt tctgattcag gttgggtaat
     5161 caatgccaat gcaccaaaag aagaaattga taaagcgtta gaattcttta atttcttata
     5221 cgctgatgaa aatcaagaaa aacttgctat tggatttgaa ggtaaaacat ttacacgtga
     5281 aaaccctaat actcaagcag gtattaaatg gttgattcaa atttacggtg aaaatgctgg
     5341 aaatgataaa gcagaactgc tgtttaaaca tggtaaccaa gcatttactc gcgttcaaac
     5401 taaattagat attgaggcac agccaggaac attccctaaa gttatgtatg atcaagtaga
     5461 taaaattaag aaagatttag gtggttttag accagatact ccggttcttt cctttacaac
     5521 tgaagaatta gatgttttaa ctaaatctga agcaggatta aatactttct ttgatgaaaa
     5581 tattattaaa ttcattgaag gacaaagaga tatgagtgag tgggattcat ttatcaatga
     5641 agctaaatct aaagacttgg ataaagttac aaaagtatat aatgatgcct acaaacgtgt
     5701 caaagataga atgaaataga ctaaatggta gctctctggt ttttcagaga gctactactg
     5761 cctgaggggg agtaagcttt gtatgatgta gtaattatag gtgcaggaag ttcgggcgca
     5821 ttggctgcaa ttgcttcggg gcgtctaggg ttaaaaactt gtctaataga gaagggaagt
     5881 agaattggtg gagttcctat taatacacta atggggtcat ttgctaatct atattttgat
     5941 gattctggta gagtaaatgc aagtaaaatt gttggggaat taatagaacg tattatcaaa
     6001 aaaggtggta ctgtctttaa ctctatggaa gaattgatga atgtaaatga tttttatcag
     6061 attacaattc cctatcaacc agaagtttat gaatcggttt taactgatat gttgattgag
     6121 tctaaagttg atattttact aaatattgaa gttaataata ttatttatga tagtaaaaat
     6181 attaaaagtc ttgaaatttt aagtaatcag gaagttaaat tgattgattc taaagttttt
     6241 attgatgcta cagggaatgc aacaattgct tctgctagtg gagctgatgt ttatgaaaaa
     6301 aattcttctt acggttgttt aatgagagtt ggaggagttg atatctcaaa gactatagaa
     6361 catattgaaa aaacaaagca gtggaactat atagaaggat ataatcagtg gttagaagaa
     6421 gtattagcaa atcgaaagta cagagccact ggagcagttt taaaagatcc agtttcttat
     6481 gatcatgccc ctatgctttc aaaagacgac cattttatga atgatgaaaa atggaattac
     6541 attaaagaaa gatgggaaaa atttagattt atttacactt tagaagtatc actatttagg
     6601 aatgaattaa aaaaagctgt agaatctggg gattttaatt ttgaaattta tcatgatgat
     6661 aaatctggag tcactatgaa tggcgacggt ataagctatg gttcatgggg tcaaaatgta
     6721 gcattaatta atgttgcaaa agcatttgga ttcaatccca aatatatgga agatgaatca
     6781 catgctaata ttctttctag aaaatataat ttaacatttt tatcttttct taaaaaatat
     6841 gtaccaggtt ttgaaaattc ttttatcctt gatcagggaa ctagagctac caacagatca
     6901 tgtaggcaca ttgataattc atctatgatg gacgaaattc ttgattttcc aatttataca
     6961 tttaagacta tgtatagcta tcaaactcct aaagaaataa cgtacaaatc aattgtaggt
     7021 ggaaaattga ataatttgtt tgtaataggt aaaggtgctt accaatccga aagttttaga
     7081 tcacaaatta gttgtatgtt aatggggata tcatcggcag cagcggcaaa aactattatt
     7141 gaagataaaa gcaatactct aaacattaat agagatttgt ttaaatcgaa cttagatata
     7201 ttatttacat gggagttttc taattggatt actgattaac aaataataag ggaatattaa
     7261 atgaatgata ctaataaaaa tcaatacttt gtttatgaat ttgatactag ctttgtagaa
     7321 atgtcttatt ctcagttttt tgaaggatat tgtattcttt tttcaaaaga accctatcct
     7381 tctttatctg atatgccaat ggaatttaga aaagaatttt taatggaaat gagtatatta
     7441 ggtgatgcga tgcttgaagt gttaaatgcc tatagaatta attatgatat cttaggaaat
     7501 tcaacacctg tacttcatgc tcatttattt ccgagataca tgtgggaaga ggaagagaga
     7561 agaaaaactg tagttcatag atatgattct tcagttttta gcaatcctga gtttgaattt
     7621 actatagaaa agcatggacc aattattaaa aaactgaggt ctgctattga tagacattat
     7681 agagagtatc aacaattatt agatgattca aactgaactc cacattttcg attagattta
     7741 ataccttgta tattacaact aggttgtgga tgatataatt ttttgaaaaa tatattttag
     7801 gaatgactta taaagcaatt atatcagagg ctattaaatc aatggccaaa gcttatgctc
     7861 cttattctga ttttaaggtt ggagctgcgt tagtaactga agataaaaaa ttttttctgg
     7921 atgtaatata gaaaatgctg ctttttctcc tacttgctgt gcagaacgag tatcttttta
     7981 taaagctgta tttaaaggag aacgttcgtt ttcaagaata tgtattgtag gtggaaaaaa
     8041 tggtatctta tcatctttta tagcaccttg cggagtgtgt cgccaggtaa tgatagaatt
     8101 ttgtaattct gattcatttg aagttatatt ggctagtgat gttgatactt ataaagtata
     8161 taaacttaaa gaactactac cagttagttt taatcaagaa aatttataac aggagggaac
     8221 tatggaatta gttgaattta aaaatggaca tgttaatacg gttcatgagc atatcgcaat
     8281 aacgaaagta aaagagtttc taaataatca tgatatacca aaagataaag gtggcataca
     8341 taaaatttct actgatttct tttacaatat aattgatatg gaaactacaa ctgaagagaa
     8401 tagaccgtgg gaaagtcata aggaatatta tgatgtccat tatctgttaa atggagaaga
     8461 aataatttta tataatttct tgtctcaaat ggaattgtct gaatataaag tagatgatga
     8521 ttggcaacaa atgaatggga cagctttatt tagtattaaa ttaaagaaag atatgttact
     8581 tttgttggaa ccaaacgatg cacataaaac aggcctattg gttgaagaac cacttaatat
     8641 taagaaagtt gtttttaagg taaaaattta actgaaagta ctttcgggga ttaagaattt
     8701 taaaatattt aagaaattgt attctaaagt tctaaaatta tagatattta atttaaagct
     8761 tgttaaaata gaatagtaa
//
LOCUS       DAVKZI010000063         8761 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKZI010000063 DAVKZI010000000
VERSION     DAVKZI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.064"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            209..1258
                     /locus_tag="VXB18_001980"
     CDS             209..1258
                     /locus_tag="VXB18_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0383126.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRNRFK
                     FCRSFKYPARRCSWC"
     gene            1230..1874
                     /locus_tag="VXB18_001981"
     CDS             1230..1874
                     /locus_tag="VXB18_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0383127.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1916..3904)
                     /locus_tag="VXB18_001982"
     CDS             complement(1916..3904)
                     /locus_tag="VXB18_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0383128.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFKKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3906..4664)
                     /locus_tag="VXB18_001983"
     CDS             complement(3906..4664)
                     /locus_tag="VXB18_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383129.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            5092..5283
                     /locus_tag="VXB18_001984"
     CDS             5092..5283
                     /locus_tag="VXB18_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383130.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5637..5909)
                     /locus_tag="VXB18_001985"
     CDS             complement(5637..5909)
                     /locus_tag="VXB18_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0383131.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5968..6417)
                     /locus_tag="VXB18_001986"
     CDS             complement(5968..6417)
                     /locus_tag="VXB18_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0383132.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRHLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(6404..8533)
                     /locus_tag="VXB18_001987"
     CDS             complement(6404..8533)
                     /locus_tag="VXB18_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0383133.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2676 a         1819 c         1699 g         2567 t
ORIGIN      
        1 ttagaaatag attttactgt cctgatcgat ttgttctgtt cttgtttcat tttactatat
       61 gttcgtaaat gaaagttcta taatgaagtt agccacccag ccctcctaaa aattagatgg
      121 ttcaactagc tgatagctct tgtaggcata agaaaacacc tctgtgttat acttgttgtt
      181 caaccacaaa cacaagaaag gcacagagat gcaagacaat tatactacaa aagccaaaca
      241 tttgacaatc gatagccgtc gcttaatcga aagatggaaa aaagaaggga aatcaaatag
      301 agaaattgcc tctctacttg gaaaagctcc tcaaactatc cacactgaaa tcaagcgtgg
      361 gacagtccga caatgtcttg gaaaagggcg cttcaaagag gtttattctg ccgactatgc
      421 tcaacagtct tatgaaaaca atcgcaagcg ctcggtcaag aaatcaagct tgaccaagga
      481 actaaaggaa aagattctcc actatcataa ccaaaaattt tcgcctgaaa tgatggttat
      541 ggctaaaggg gttaacgtgg gaatttcaac catttactat tggattcatc atggaaaatt
      601 ggggttaagc aagcaggatt tgctttaccc tagaaaagga aaagcgctta agaaacaggc
      661 tagcaccaac tttaaacctg ctggtcaatc catcgaacag cggcctgaag ctatcaatct
      721 tcgcttggag aatgggcatt atgagattga tacggttcta cttacgagag cgaaaaacta
      781 ctgcttgctt gtcttgacgg atcgaaagag tagacatcag atcatccgat tgattccaaa
      841 taaaagtgct gaggtggtca atcaggctct aaaactcatc ttaaaacaac acaagattct
      901 ttccatcacg gcagataatg gaacggaatt caatcgcttg tttgatgtat tttctgagga
      961 gcacatctat tatgcgcacc cctatgcctc ttgggaaagg ggaactaatg agaatcacaa
     1021 caggctcatt cgtagatggt tacctaaggg aaccaagaaa atgactccca aagaagtcgc
     1081 attcatcgaa aagtggatta acaactatcc taaaaaatgc ttgaactaca agtcacccag
     1141 agaagacttc ttgatggcta acttgaactt gaaatttagc gtcagaaaca aatcacgaaa
     1201 tcgattcaaa ttttgcaggt cgtttaaata tcctgcgcgc aggtgttctt ggtgctaacg
     1261 atggaattat ttccattgct ggtgtggtta tcggggttgc cagtgccacg accaatatct
     1321 ggattatctt tttatcagga tttgcggcta tcttagctgg tgccttttca atggctggtg
     1381 gagaatatgt atccgtttca actccaaaag ataccgagga agctgccgtt tcgcgagaaa
     1441 aactcttgtt agaccaagat agggaactag ccaaaaaatc cctctatgct gcttatatcc
     1501 aaaatggaga atgcaaaact tctgcccaac tcttgaccaa taagatcttt cttaaaaatc
     1561 cactcaaggc tctggtagag gaaaaatatg ggattgagta tgaagaattt accaatcctt
     1621 ggcacgctgc catttctagc ttcgttgcct ttttccttag aagtttgcct ccaatgctgt
     1681 cagtgaccat attcccaagt gaatatcgca tccctgctac tgtccttatt gtcggtgtgg
     1741 cccttcttct cactggttac actagtgcca gacttggaaa ggatccgact agaacagcta
     1801 tgattcggaa ccttgctatt ggtctcttga ccatgggagt taccttcctg ctcgaacaac
     1861 ttttcagcat ttagaataca agaaatacct cgattttgaa gtcgaggtat cttttttaca
     1921 tttgcacaat cttgcgataa cttcttgaag taatcatgaa aatcagcaca taggcgatga
     1981 ggaagatagc gcagatagac aaggtcacaa tcaacatcat agtcgtatcc agtacaccaa
     2041 tcacttttaa aatcaggcta agcatatggt aggcaaaggc gagatgtatg aaggcaaaga
     2101 gcaaaggaag gaagaaaaca gttaaaacct gtttgttgat ggtttgcttg atttgctttt
     2161 ggtccaaacc gactttctgc aagataataa agcgttcacg gtcttcgtag ccttcagaaa
     2221 tttgtttgta gtagatgacc agaacagttc cgaccataaa gataatggat aggaaaatac
     2281 cgataaagaa gacaccacca aagagggcac tcatctgaga actagcatct gctagattgc
     2341 taccataaac atagctacct tctgtgtcta attgagcatt aaattgattg aggtagtttt
     2401 catactcctc agcgaccttg agttgttctt cttcgctggc atctacattc ataccaccgt
     2461 aaaactgatt atagatagcc gaatctggga attgatccaa aaaggcttgt aaatcaggaa
     2521 caacaaggta attgtaatca gtagtcaaga tattaaactt atttggaaca tggttgacaa
     2581 tgaaatcttt attaaattct tctttgacag aaaattgatg atcatttaga gttagagctt
     2641 tctgtccttt cagtccgtca tttttggcaa agagaccgac ctcatttcct gatagagaca
     2701 gtttttgacc agtcatattt tcataatctt tttggtcaaa taccatgaaa actgtttttg
     2761 gttggacacg gttttgtcct tttttaaaaa tagttaactt ggttccttct tgattcgcaa
     2821 cagcaaagta agtgtaacga agcacttctt tctctttaat cttataacct ttgtcacttg
     2881 caaactggct caagagtttg tccaaatctt ctttttcaac attttgccct gaaaccccaa
     2941 aatcatgagg atttagaact tttttaaagc tttctgagga attgaaaatg cttgtcgctg
     3001 ctgacatggt taccaaaacc attgttgaca agatagcgat ggtggctagt ccaactgcat
     3061 ttttcttcat acggaaaatc aagttagaaa cagatatgag attatttggt tggtaatagt
     3121 atttcttatt tttctttaag atttggagga aaacggtaat ccctgcatta aacaagagat
     3181 aagtcccaaa gataaccagt aaaacagcta tgaagaaggt tgttaaggct gtaagaggat
     3241 cttttaccgt aagggcaaga taatagccaa ttcctaaact tatggaacca agaatggttt
     3301 ggagaggaag gaagcgacct tttttctctc cactagcttt ctcacgagag agctggaggg
     3361 cattcatacg ggcgattcga agggcattca ggaacatgag gcctaggaaa atcaaaccga
     3421 agacaacaag cactgtaatg acaactttcg tctggaaggt agcaaccagc tcaaccttca
     3481 atttcattag tttgagcagg aaagcgaaaa ttaacttgtc aaacaaggct ccaataccga
     3541 tacccgctcc aacagttaga atcccaaata ccactaactc cttaaaggtc atactgataa
     3601 gatgacgctt ctccaagccc aacatgccat aaattcctag ttccttggaa cggttcttca
     3661 tgacaaaact attggcatag agaacgataa tggctgacgc aagggtgacg acaaacatac
     3721 caaatccaag tgtagcctga atggttgttc ctccacggat ttccgcaatc ttaggattga
     3781 aggttagaga ataaaagaga taggtgacag tgactgccaa gagaacagcc agcgcaaaag
     3841 gatagtagag tttgcggttt ttaatcaagt tcgataccgc taacttattg gttaatcgaa
     3901 acatactaat tcacctcgct tgccatgaca gtcaaggtat cagagatttc ttggaacatc
     3961 tgacgttctg tcttctctcc acggtagatt tgattgtaaa gaatgccgtc tttgataaag
     4021 agtacacgtt tagctctgct agctgctgct gttgagtggg ttaccatgag aatggtttgg
     4081 ccgcgctcat tgatttcatc aaatacatca agtaaggctg cagatgactt ggagtcaaga
     4141 gctcctgtcg gttcgtccgc aaggagaatt tcaggttcag tgatgatggc gcgtgctact
     4201 gctacacgct gtttctggcc accagaaatc tcgtaagggt acttctcttg taattggttt
     4261 attcccagat tctcagctgt caccaccaat ttcttcatca tctctgtaat aggtcttctt
     4321 gacaagacaa gcggaagcaa gatattgtcc tttacagata gagtatctag caagttaaag
     4381 tcttggaaga caaagcccaa cttttcacgc cggaaactag aagcctgtga atttttaata
     4441 gttgctgtat cagttccatt taagtaaacc tgaccacgac ttggtttgtc cagcatagct
     4501 aggatattga gaagagtgga tttaccagaa ccagactcac ccatgatggc aacatagtca
     4561 cccttttcta cggtaaagtg aatatccttg agggcttcta cttggttgcc ctgaaaacgt
     4621 gttttataaa ttttttgaac gtgttttaca tctaaaagtg tcatgagaat ctcctttctt
     4681 aatatcccat aaaatgaaat gtagcttgca tcatagtgca tcccagctga acgcgctcaa
     4741 tttctttgtg acttggtttt ctagttttct tatgtacgat ttgtttcatg atgttactcc
     4801 tttgttcttt atgagtctag tttacatcaa aaaaagaccg cttgccataa cctaacctta
     4861 caaaagagac tttaatctta catttttgta agattggggg aaatataagc aaaattactt
     4921 agaaaatgat ttgatttcct atttttaaag ttgtaaaata taagtgcgaa aaggcttact
     4981 ttgaaaagga ggaagcggga actaacattt tagtaaggtt acctagatga cacaccatta
     5041 aattgaacac tttcaaatcg aactacctat aaggaaagaa ggtgcgcttt aatgaaacat
     5101 aaagaacata tactcatcgg atttctctat ctgctctctc cattcatcgg tcagctctta
     5161 gttgaacaca cacactttat cggtacagaa tttaccggca ctgcttatgt tatttgctgg
     5221 ttatcagttg ttatcagcat ccaccatttt tccaaaaatg tattgtctca gcagcaaaaa
     5281 tagattaaaa aactgcattt aaattactgc ttttatagta aaatgaaata agaacaggac
     5341 aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat
     5401 tctagttcca atccactata gtttgtagat gaagctggcg aaatattatt aatactattc
     5461 aaaaatcaaa gtgcaaacta tatcaacttc acattgccga ctaaattata gcctgcggct
     5521 ggcttcctag tttgcacttt gatttttatt gagtataaaa gtaaaaaagc tttaaatcaa
     5581 gcagtttaga ctattgattt aaagcttttt gcgtattcca aatcttttgt aaaacctcac
     5641 caaaaccagc cttcattatc gtcaatggct tgagcttctt tgcgtttacg tgggcctgtt
     5701 ccgtacattt ctgcttcgat ttcttccttg gttggcatga tagaagctag gatgatatag
     5761 ataatcaccc caagtccaaa gtttgcgact gtaaaaatgg caaacagaaa acgtacaagg
     5821 gtaacatcaa agttccactt gtctgacaga cctgccaaaa ctcctgaaat catgcgattt
     5881 cgtctcattt tataaaattt actgttcatg atatttcctc tttctgctag gttagacata
     5941 gtatatcacg ggtaggctcg gctttcatca gtcctcaggt tgatttatta gtagcaattt
     6001 acctcgacaa agtccacagc gatagcgttg ggtatcaatc ctacgcttac gctgataagt
     6061 ttgctggcag gattggcaac gatagagctt gattggcttg gagttactat tgggcaagga
     6121 tggtacaaac cgtaatccat ctactgcttt caacagttcc ttaaaatccc gatccttgtg
     6181 ttgatagcct ttcccttgaa aatagaggtg ataatgacag agttcatgtc ggacaatttt
     6241 cctaaaaacg tccaacccca gttcctgata aaccttggga ttaaaatcca aatgcccatc
     6301 tttggggaaa aatcgcccac ctgtcgaacg tagatgccta ttccactgga catgatggat
     6361 aaaaggtctg ccgaagtctt ctagtgaaac ctgcttgacg taatcagtca gtttcatttg
     6421 gagctaggag agacagatta actttttcac gttcagtatc aattttctta acccaaacgc
     6481 tcaccaaatc tccaactgcc accacttgac tagggtgttt gataaacttg cgactcatat
     6541 gggaaatatg gatgagaccg tcctcatgaa ttccgatatc aacaaaagca ccgaaatcaa
     6601 caacgttacg caccactcct tctagctttt gtccaaccac taagtccttg atatctagga
     6661 catcttgacg gagaactgga gcatcaaagg aatcacggaa atctcgacct ggtttgagaa
     6721 gatctgcaat gatatcttta agagtttctg gaccaaggtc taactcttgc gccatttcct
     6781 tgactgaaag cgacttgagt ttactttggg cctcttcatt cagatcctta atgtccaagc
     6841 atttgaagag ttccttaacg gcagcgtaat tttctgggtg aactcctgta ttatcaagga
     6901 tattgctact ttcagggata cggaggaaac cagcagcctg ttcaaaagcc ttggccccca
     6961 aacgaggaac tttcttgatt tgggagcgtg aagtgatttt tccctcttcc tcacggtatt
     7021 tgacgatatt ttcagaaatt gttttattga gtccagccac gtgagaaaga agagctgggc
     7081 tagctgtatt aacattgaca ccgacttggt taaccaccgt atccacgaca aagtccagac
     7141 tctcagatag tttcttctga ctgacatcgt gttggtattg accgacacca attgacttag
     7201 gatcgatttt gaccaattcc gcaagaggat cttgcaaacg acgggcgata gaaatggcag
     7261 agcgtttttc aacggtcaag tctggaaact cctgacgagc aagttcgctg gcagaataga
     7321 cagaagcacc actttcatta acgataacat agctgacttc agggaaatct ttcagaactt
     7381 ccgctacaaa agcttcgctt tcacgactgg ccgttccatt tccaatggca ataatctcta
     7441 caccgtattg accaattaaa tctgctaaat ctttcttggc ttcttcgatt tgacgagctg
     7501 atgctggttt aacaggataa ataacctgag ttgtcagcat ttttcctgtt gcatccacga
     7561 cagctagctt ggcacctgta cgaaaggctg ggtcaaaccc aagaaccacg cgccctttca
     7621 gtggagcaac caagaggaga ttgcgcagat tgtcagaaaa aagttggata gctccctctt
     7681 cagctttctc agttaattct gtccgaatac gacgctcaat agcaggcaag acctttttct
     7741 taacggattg ctgaacaact tcatcaatat aagcattttt caccttgaaa cgagtagcaa
     7801 agaaggcaag aatacggtcc gtcgcatgtt caaaaccgat cttcaagaca ccaagtttct
     7861 ccccacgatt gagagccaag gtacgatagc cttgcatagt tccaactgtc tctgaaaaat
     7921 cataataaat ctgaaaaacc tgcttttcat caagactttc atccttggct tgagaagtga
     7981 gtttagagtg tctcagcact tcctgataag tcatagaacg caaggtcaca tcttccgata
     8041 aggcttcgac caaaatatca actgcaccgg tcaaggcttc cttgccagtc gcaaatcctt
     8101 cacagacgaa cttttcagct tctttctcta agtcaactat attctgcaaa atcaagcgag
     8161 caagaggaaa gagtccagct tcacgggcaa tggttgcctt ggtacgacgc ttttccttat
     8221 aaggaagata gagttcttca acgtctgcta atttttcggc aactaagata gcttcttcca
     8281 attccttggt caacttacct tgttcttgaa tcttagctaa gacagcttcc ttacggtcat
     8341 tgagatttgt cagactttta tccaaatcaa taatagcctt aatcgccacc tcatccagac
     8401 taccagtcat gtccttgcga taacgcgcga taaagggaat agtcgcccct tcagctgtca
     8461 aacttagaac ggtatcaatt tgctttaacg tcactcccaa atcctgagag attttttcat
     8521 attttttatc cataaatcta ttataccaca agctaaacgt ttcaaattaa ctcgtagaac
     8581 atttaaaaaa tatgtaggaa atagatttat atgctacagc gcaataactt gcacttaaag
     8641 agcattgcca ccttttttta accaagctat gatatcaaaa gtatttaatg gatcagacat
     8701 aatagccagt tctggaagat gttcctgacc tggaataaca cattgacttt tcaaattttt
     8761 a
//
LOCUS       DAVKZI010000064         8240 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKZI010000064 DAVKZI010000000
VERSION     DAVKZI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8240
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.065"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..241
                     /locus_tag="VXB18_001988"
     CDS             <1..241
                     /locus_tag="VXB18_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0383134.1"
                     /translation="CYREEQSGCLDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNVS
                     EVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            254..1729
                     /gene="galT"
                     /locus_tag="VXB18_001989"
     CDS             254..1729
                     /gene="galT"
                     /locus_tag="VXB18_001989"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0383135.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNKHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1742..2695
                     /gene="galE"
                     /locus_tag="VXB18_001990"
     CDS             1742..2695
                     /gene="galE"
                     /locus_tag="VXB18_001990"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0383136.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATNPYGYTKVMLEQILKDVHVADSEWSIALLRYFNP
                     IGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFGNDYDTLDGTGVRDYIHVVD
                     LAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFESVNKIPIPYKIVPRRSGDV
                     ATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNGYN"
     gene            2860..3519
                     /locus_tag="VXB18_001991"
     CDS             2860..3519
                     /locus_tag="VXB18_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0383137.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3544..4611
                     /locus_tag="VXB18_001992"
     CDS             3544..4611
                     /locus_tag="VXB18_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0383138.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQTEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4715..5725
                     /locus_tag="VXB18_001993"
     CDS             4715..5725
                     /locus_tag="VXB18_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383139.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLNPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISNQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFTLKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5737..7428
                     /locus_tag="VXB18_001994"
     CDS             5737..7428
                     /locus_tag="VXB18_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0383140.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNIIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7431..8141
                     /locus_tag="VXB18_001995"
     CDS             7431..8141
                     /locus_tag="VXB18_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0383141.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2789 a         1133 c         1626 g         2692 t
ORIGIN      
        1 ttgttataga gaggaacaat ctggatgttt agatatggtt gttatacaaa aacagaatga
       61 gatagaagag cttagtataa atatggaaaa gaaaataatg aattacatat ttgaagatga
      121 tgggaacgtt tctgaagtaa ttagtgcttt agatattatt catcaccttg ataaaattgc
      181 tcatactacg caagcaattt ataaatggat aatgtataga aaatatggga acataaatta
      241 gaaagaaaaa tatatgaaaa caattattga taattttgtt gatagagtaa ttgaatacgg
      301 aatgtataat gaaattgaca aaatatatgt gaaaaataga gtactagcgt taataggtga
      361 ggagggaatt gatcgcattt ccgatgaaaa tgacctgaaa caaataaaag attacttagt
      421 ggaaatcgcc ttaaaaaacg gtaaaattaa agatttaatc gaggaaaagg aatgtttagg
      481 agcagagtta atgaatttca tagttccttt acctagtcga ttaaatgata ttttttggag
      541 ttcatatgat atatcacctc aagaagcagt tgaagagttt tataagttaa gtaaagatag
      601 tgattatatt aaaacttctg ctattgctaa gaatattgag tttcgagcat caactaaata
      661 cggagagcta gagattacga taaatttgtc aaaacccgaa aaagatccaa aaacaattgc
      721 tgctgaaaaa ttagtaaaag caactaatta tcccaaatgt ttactatgta tggaaaatga
      781 aggatatcag gggcgaataa attatccagc acgttcgaat catagaatta ttcggttgaa
      841 acttggtgac gaagtatggg gattccagta ttctccctac tcgtacttta ataagcatgc
      901 gatatttttg aatagtcaac atgtaccaat ggctattacc tctaaaacat ttgaacaatt
      961 attggagatt gttgatattt tgccaggata ttttgctggt tcaaattctg atcttcctat
     1021 ctcaggaggc tccattctta gtcataacca ctaccaggga gggaaacata ttttcccaat
     1081 ggaaaaagca aaatttgaga gtgaattttg ttttaaagac tttgaggatg ttaatgctgg
     1141 tattgtaaaa tggccaatgt cagtaattag gttacaaagt gaaaataaaa atcgcttgtt
     1201 agatttagct actaaaattc taaataagtg gagagaatat tcagatttag aagtagacat
     1261 cattgctatg actgaagatg tcccacacca tacggtgact cctattgctc gtaaagtgga
     1321 cgggagatac gaattagata ttgttctaag agataatcat actactgaac aatacccaga
     1381 tggtgttttc catcctcatc aagatgtaca acatattaaa aaggaaaata tcgggttaat
     1441 cgaagtgatg ggacttgcga tattaccacc tcgtttgaaa ccagagttag aagaagttgg
     1501 aaaatatctt ttaggagagg ataatgcaat tgcggattat catttagaat gggccgacca
     1561 attgaaagaa aaatatcctc gcattaataa agaagaggtt aatagcgtag ttcaacacga
     1621 agcaggacaa gtgtttgcga gagttctgga agatgcagga gtttataaga atacaccgtc
     1681 tgggcatgaa gcgtttatga gatttgttaa gtcggttgga attaattagg aggaaaccca
     1741 gatggcaata ttggtaacag gcggagctgg ttatattggt agccataccg tagtagaatt
     1801 actaaattta ggaaaggaag ttatcattgt cgacaacctt tcgaactcta gcaaattggt
     1861 gctagaccgt attgaagcaa ttacaggaat acgtcccgtg ttttacgaat tagatgtttg
     1921 tgataaacaa gcattgagaa aggtatttga acaagaatcg attgatgctg caattcattt
     1981 tgcaggttat aaagctgtcg gagaatccgt gcaaaagcct gtgatgtact acaaaaataa
     2041 tattatgagt acattggcac ttgttgaagt gatgtcagaa tttaatgtta aaaagattgt
     2101 cttttcttca agtgcgacaa atccttatgg gtatacgaaa gtgatgcttg agcaaatttt
     2161 aaaagatgtt catgtggcag attcagaatg gagtattgcg ttgcttcgtt atttcaatcc
     2221 aattggtgct catgagtctg gtttgattgg ggaagatccc tcaggaattc ctaacaactt
     2281 gatgccttat attgcacaag tagcggtagg taagctatca gagctaagtg tgttcggaaa
     2341 tgattatgat acgcttgatg gtactggtgt gcgtgattat atccatgtag tagatttagc
     2401 aataggacat ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa
     2461 cctaggctcg ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa
     2521 taagatccct attccttata aaatagttcc aagacgttca ggagacgttg caacttatta
     2581 tgcaaatgca gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga
     2641 catgtgtaga gatacatgga attggcaatc aaaaaatccc aatggctata attgatgata
     2701 ctgtctatat gagtgctgta ttttggaaaa attacttaat cttttaatga aagataaatt
     2761 taaaaaaaat gtttgacagc gcttgacaaa ggaaacggtt tcattgtata atgtaaacac
     2821 aatgacaccg atgtcaaata taaaaaagaa ggtctttata tgaaaaactt aacaaaaatt
     2881 aagttcaaag aaaatgggga atttaatcat ttccctggga atacagttgt agcaaatctt
     2941 tatactaaac aagatttgat ggaagttgtt gatattattc aatcacgtta tagagaatta
     3001 ccatttatcg ataagtttac tttaactcca aggaattcta ttcacatgac tgtaattgaa
     3061 ttgttgtgcc atgaaaatcg tgaaacggag ttttggagca gtaatcttcc tctagataca
     3121 cctttacagg aaatacatga ttactttgct aaacaacttg aaatttttcc attgttggat
     3181 gaagaaattt atatgcgtat aactgaaatg ggaaaacaaa acatactagt tgaacctgca
     3241 gatgaagctt ctgcaaagag attagaagaa attcgtactt atgtctcaga aaaagcaggt
     3301 gtttgtttcc ctaatcatga tagatatcaa ttccatattt caattgggta tcttcggatt
     3361 cctctaaccg aagaggagga agaagagttt actaaagtca gagcagaatt aactgaaatt
     3421 ttattagaga agattccaac tattactgta aaccgtattg actatactgt atttgaagat
     3481 atgagacaat ttgttccata tcacgaaaaa tttaaataaa ataataaaaa aggagaactt
     3541 atcatgaaaa aaatgaaagt ttggtctact gtacttgcaa cgggagttgc tcttactaca
     3601 cttgctgctt gctctggagg ttcaaattct acgactgctt cttcatctga agaaaaagct
     3661 gataaaagtc aagaattagt aatctattcg aactcagtct caaatggtcg tggtgattgg
     3721 ttgactgcta aagcaaaaga agctggtttt aatataaaaa tggttgatat tgctggcgct
     3781 caattagcag accgtgttat tgctgagaag aataatgcag ttgcagatat ggtatttgga
     3841 attggtgctg ttgattcaaa taaaattaga gatcaaaaat tactagtaca gtacaagcct
     3901 aaatggttag ataagattga tcaatcttta tcagataaag ataattatta taatcctgtg
     3961 attgttcaac cattagtttt aattggggcg cctgatgtaa aagaaatgcc taaagattgg
     4021 actgaattag gtagtaagta taaaggtaaa tattcaattt atggtcttca aggtggtaca
     4081 ggacgggcaa ttctagcaag tatcttagtt cgttatcttg atgaaaaagg tgatttagga
     4141 gtatcggaaa agggctggga agttgcaaaa gaatactttg caaatgccta tactcttcaa
     4201 aaaggtgaaa gctcagttgt taaagcgtta gataaagaaa gcccaattca atacggtatg
     4261 atctggggtt ctggagcgtt aatcggacaa aaagaacaaa atgttgaatt caaagttatg
     4321 actcctgaga ttggtgtacc atttgtaact gaacaaacta tggttttaag cactagtaaa
     4381 aaacaagcgt tagctaaaga atttattgat tggtttggtc aaacagaaat tcaagtagaa
     4441 tatagtaaaa aatttggatc tattcctgcc aataaagatg ccctaaaaga gttacctgaa
     4501 gatacgaaaa aatttgttga tcaagtgaaa ccacaaaata ttgactggga agctgttgga
     4561 aagcatttgg atgaatgggt agaaaaagct gaattagaat acgtaaaata agaaataaga
     4621 gttatttttt atgtccaagt ctctctatta tttctaaatt tatggaagaa ataaagagag
     4681 gcttttggtt ttagtgatag agggagttag tgagatgatt aaatttgata atattcaaat
     4741 taaatatggt gattttgttg caattgataa tctgaattta gatatacatg aaggggaatt
     4801 ctttactttt cttgggcctt caggatgtgg taaatcaact actttgagag ctttggtagg
     4861 ttttctaaat ccatcatcag gaagtattga agttaatgga acagatgtca ctcatttgga
     4921 acctgaaaag cgtggaattg gtattgtatt tcaatcttat gcgctatttc caactatgac
     4981 tgtttttgat aatattgcat ttggtttaaa agttaagaag gtagctccag atgttattaa
     5041 agctaaagta tcagcagtag cagcaaaaat taagatctct aatcaacagt tacagcgtaa
     5101 tgtatcagaa ttatctgggg gtcaacaaca aagggtagca ttggctcgtg ctctggttct
     5161 tgaacctaaa attctttgtc tagatgaacc attgtcaaac cttgacgcaa aattacgtgt
     5221 agatttgaga aaagagttga aaagacttca aaaagagtta ggtattacta ctttatatgt
     5281 tactcatgat caagaggaag ccttgacttt atctgataga attgcagtct ttaacaatgg
     5341 atacatcgaa caggtcggta caccagtaga aatttatcat aattctcaaa ctgaatttgt
     5401 atgtgatttt attggagata ttaatgtttt gaccgatgaa acagtccacg aagtattatt
     5461 gaaaaataca agcgttttct tagaagataa aaaaggatac attcgattag agaaagttcg
     5521 attcaatcgt gaaactgaac aagatttcac tctaaaaggg acaattattg atgttgagtt
     5581 ttctggagtt acaattcact atacaataaa agtttctgaa agtcagattc ttaatgtaac
     5641 aagtattgat agtcaggctg ctattagatc tgtcggagaa agtgtggaat tatttatcac
     5701 tccatcagac gttctgcaat tttaaggagg tgcagtatgc gtcataaatt aaatttaaaa
     5761 gattggctta ttcgtttagg gttaatctgg ttcttagtaa catttattat ttatccaaac
     5821 tttgatctag tagtgaatgt atttgtaaaa ggaggagaat tttcccttga tgctgtacat
     5881 cgtgttctaa aatctcagag ggcacttcag agtattatga acagttttaa gttagcattt
     5941 tcactcatta ttacagttaa tgtcgtaggt attctttgtg ttctatttac agagtacttt
     6001 gatattaaag gtgctaaaat tttaaaatta ggttatatga cctctttaat ttatggagga
     6061 gtggttttag cgactggata taaatttgtc tatggtcctt atggattgat tacaaaattt
     6121 ttacaaaata ttatcccttc tttagaccct aactggttta ttgggtatgg tgcagtctta
     6181 ttcattatga cattttcagg aacggctaat catacattgt ttttaacaaa tacaattcga
     6241 agcgttgact atcacactat tgaggctgct cgaaatatgg gagcaaaacc atttactgtt
     6301 ttccgaaaag tagtgttacc aaccttaatt ccaactctat ttgcacttac tattatggtt
     6361 tttcttagtg gtttatctgc agtagcagca cccatgattg ttggtggtaa agaatttcaa
     6421 actataaatc caatgattat tacatttgca gggatgggga attctcgtga tttagctgcc
     6481 ttacttgcaa ttattttagg tattgcaact acaattttgc ttactatcat gaataagata
     6541 gaaaaaggtg gaaattatat ttctatctct aagactaaag cgcctcttaa aaaacaaaaa
     6601 attgcgtcta agccttggaa tatcattgct cacattgtag catatggatt gttcacagtt
     6661 ttcatgcttc cactaatttt tatagtatta tactcattta cagatccagt tgcaattcaa
     6721 acaggtaact taacattatc aaactttact ttagaaaatt atcgcttatt ctttagtaat
     6781 agtgcggcat tctctccatt cttggtcagc tttatttatt ctattattgc tgcgacaaca
     6841 gcaacaattc tcgcagttgt atttgctcgt gttgtcagaa aacataaatc tcgttttgat
     6901 ttcttatttg aatatggtgc tctacttcct tggttactac caagtacact tttagcagta
     6961 agtttattat ttacttttaa tcagccacaa tttcttgtct tgaatcagat tttggtaggt
     7021 agtttggtaa ttctacttat tgcatatata gttgtaaaaa tcccattttc ttatagaatg
     7081 gtacgtgcta ttttatttag tgttgatgat gagatggaag atgcagcaag aagtatgggt
     7141 gcttcacctt tttatactat gatgaaggtt atcattccat ttattttacc ggttgttctc
     7201 tctgttattg ctttaaactt taactcttta ttaactgact tcgacttatc tgtattcctt
     7261 taccatcccc tagctcaacc attaggtatt acgattcgat ctgcaggtga tgaaacagca
     7321 acatctaatg cacaagctct ggtatttgtt tatacaattg ttctgatgat tatttctgga
     7381 acggtattat acttcacaca aagaccgggg cgtaaagtaa ggaaataatc atgacagcca
     7441 ctagtcttgg gttatcaaat attgaaatag ttgtcaggat tgttttatca gtagtcattg
     7501 gtagtataat tggtttagag agagggagca aatcccagcc tgcaggcatc cgaacttata
     7561 gtattgtttg tctagctgca tgtttgatta tgatgacgaa tgaatacgta tcttataaat
     7621 ttgggacagg agatcctaca cgattaggag ctcaagttat atcaggtgtg ggttttctag
     7681 gcgctggaac gattcttatt acagataaaa agaaaattac aggtctgaca actgcagcag
     7741 gcatttgggc ttcggcagga attggattag ctattggagt aggtttttat gagggagctc
     7801 ttttagtagc tatttctgtt tggggtgtga tatccatgtt ccaaccacta aaaaaatatc
     7861 tgcaaaatcg ttctaaaatg attgaattgt atatagtggt taaatctaca gaagcctata
     7921 atcgtgtatt ggtttattgt gcagaaaatg gtatcagaat gaccgattca agaacagcgt
     7981 ttggagatgt taattctgac agaattgaat actttgatgt tccagataaa aaaatagcgt
     8041 catttattac tctggaatta tcaggtagat ttgaacatct tcgactgatg gaagaaattg
     8101 ctaatattgt aggtgttatt tatgtcgaag aaattagctg aaatttagta aacaaaggga
     8161 cagatgtttt tgtccttttg ttttttagat gttttaatca tctaattttt gagtagattt
     8221 ttgctcagag gtttttatga
//
LOCUS       DAVKZI010000065         7575 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKZI010000065 DAVKZI010000000
VERSION     DAVKZI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.066"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..908)
                     /locus_tag="VXB18_001996"
     CDS             complement(<1..908)
                     /locus_tag="VXB18_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0383142.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYL"
     gene            complement(910..1929)
                     /gene="galE"
                     /locus_tag="VXB18_001997"
     CDS             complement(910..1929)
                     /gene="galE"
                     /locus_tag="VXB18_001997"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0383143.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESSDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            complement(2194..2274)
                     /locus_tag="VXB18_001998"
                     /pseudo
     CDS             complement(2194..2274)
                     /locus_tag="VXB18_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(2275..3378)
                     /locus_tag="VXB18_001999"
     CDS             complement(2275..3378)
                     /locus_tag="VXB18_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0383144.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            complement(3395..4192)
                     /locus_tag="VXB18_002000"
     CDS             complement(3395..4192)
                     /locus_tag="VXB18_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0383145.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            complement(4179..4856)
                     /locus_tag="VXB18_002001"
     CDS             complement(4179..4856)
                     /locus_tag="VXB18_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0383146.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            5405..5821
                     /locus_tag="VXB18_002002"
     CDS             5405..5821
                     /locus_tag="VXB18_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383147.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKVPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNRLSEFKAPKILSDYQCGMHSLVHYRYGAF"
     gene            5867..6397
                     /locus_tag="VXB18_002003"
     CDS             5867..6397
                     /locus_tag="VXB18_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV0383148.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPNWKMDLFSEEEKRNYFQTTCEIS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LYNIVNIVSDIHKLGI"
     gene            complement(6471..7575)
                     /locus_tag="VXB18_002004"
                     /pseudo
     CDS             complement(6471..7575)
                     /locus_tag="VXB18_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2261 a         1629 c         1401 g         2284 t
ORIGIN      
        1 ataagataaa gtggtctttt tttagtctct aaataaatct tactgatata cttaccgaga
       61 atcccaatgg tcaagagttg aatgcctcca agaaagagaa taacagccat cagagaggtc
      121 caaccagatg tcggattgcc caaaatgagg gtccgaacca caacaaaaaa ggtcatcagc
      181 agagaaagaa aacaagatag gagaccagct acaaaggcta tagtcaaagg gaaatctgaa
      241 aaattaacaa tcccttcaat ggagtaaaaa aagagttgcc taaaactcca actggtcttg
      301 ccagcctgcc tttcgacatt tggatagtcc agatagtggg ttttaaagcc gacccaggca
      361 aagagtccct tagaaaaacg attggactca gtcaagctta aaatggcatc gaccacagac
      421 cttctcatca tacgaaagtc acggacaccc gacggcagag ctactgggct gattttttgc
      481 atgaggcgat aaaagagaac agcacagaaa ctgcgaaaga agggttctcc ctcccgacta
      541 gttctccgtg tcccaacgca gtccaagtct acatttttgt ctagtacatt tttcatctca
      601 aacaacatac taggaggatc ttggaggtct gcatccatca ccaccaccaa atctcctgtc
      661 gcatattgca agcctgcata aagggctgct tctttgccaa aatttcgaga gaaagaaata
      721 taatggactg ccggattttg ctcccgatag gcctttaaga gttccaaggt cccatcactt
      781 gatccatcat cgacaaagac atactcgatt tctgtttcca aatctggaag taaagcttcc
      841 agagcctgat aaaaaagagg aagtacttcc tcttcgttta aacaagggac gatgattgaa
      901 atcatcatct tagtcttcaa atccatttgg atgcttgctc tgccaacgcc atgcgtcttc
      961 acacatttgg gtgatgtcga gttctgcttc ccaaccgagt tctgctttag cttttgctgg
     1021 gtctgagtag caggcagcga tatcacctgg gcgacgttct acgatgcggt aaggaatagg
     1081 acgtcccacc gctttttcca tgttttggat aatttcaaga actgagtaac ctttaccagt
     1141 tccaaggtta taaacgttta gtcctgaacc tttttggatt tttttcaaag ctgcaacgtg
     1201 acccttagcc aaatcgacaa cgtggatata gtcacgaaca cctgttccat cttccgtatc
     1261 gtaatcgtct ccaaacactt gcacttgctc taattttcca acggctactt gagtcacata
     1321 tggcaagaga ttgtttggaa taccgtttgg attttctccc aaatcactac tctcatgggc
     1381 tccgattggg ttaaagtaac gaagcaagac aacattccat tctgagtctg ctttgtaaat
     1441 atcagtcaaa atttcctcta gcatgagctt agtacgaccg tatgggttgg tcactgaaag
     1501 tgggaaatct tccaagatgg gcactgtgtg cggatccccg taaactgtcg cagaagaact
     1561 gaagatgatg tttttacagt tgttttcttc cattgctttc aaaaggctga cagttccagc
     1621 gatattgttg tcatagtagg caagagggat acgtgttgat tcgccaacag ccttcaaacc
     1681 agcaaagtga atgacaccag tcggttcttc ctgcttgaaa atatctctga gggtatctgt
     1741 gtcacgaata tctgcctcat agaaaggaat ctcaactcct gtgattcttt caacaacttc
     1801 taaactctta cgattgctat tgacaagatt atccaccaca acaacttgat ggcctgcttg
     1861 gatcaattca ataacagtgt gggttccaat aaaaccggca ccaccagtta ccaaaatctt
     1921 ttcttgcatc ttttttcctc gattctcaga ttattttttc ttattttacc atttttgaca
     1981 gggaatgtca tttgccatcc taaactacct gataaaattt cagtaaaatg cttatactct
     2041 tcgaaaatcc aattcaaacc acgtcaacgt cgccttgcca tgggtatggt tactgacttc
     2101 gtcagttcta tctacaacct caaaacagtg ttttgagctg acttcgtcag ttctatccac
     2161 aacctcaaaa cagtgttttg agctgacttc gtcagttcta tccacaacct caaagcagtg
     2221 ctttgagtaa cccgcggcta gtttcctagt ttgttctttg attttcattg agtattattc
     2281 gctttttact cgtttgacat agttttcaat tgggtaattt agagggtcca aggtcaactc
     2341 cttgtcttgg atcagttggg ctagatggta accaatgata ggaccagttg tgaggcctga
     2401 tgaacctagt ccactggctg catagacacc tgccaattct ggcacctgcc caaagaaggg
     2461 agagaaatca ctggtatagg cacggattcc cacacgctca gcccttgaag tcgctctagc
     2521 taaaactggg taatgaggca aggccgcctc ctccatttgt tggagcaagg gttcatctac
     2581 cgtcaaatca aatcccatgt cattttcatg ggtagcgccc aaggataatt tcccacctgc
     2641 aaagggaatc aaatcccact ccccttctgg catgacaaca gggtaagctt ccatgtcttg
     2701 ggcaagctga taatctcgta gttgtccttt ttgaggacgg acatccactt cataacctaa
     2761 aggctctaac atgtccccca accaagctcc cgttgccaaa ataacctgat caaacacctc
     2821 ttcgccaatc tggtagcctg atgataagag tgtcagagtc actttttctt tgaccagctt
     2881 gacatgactg gcttctagca gacgagttac caagagttgg ccatctactc tcgctccacc
     2941 agaagcatag agcaggcggt caaatccctg caaaccaggg aataattcat tagctgaagc
     3001 ttggtccaga atggctaatt gccctatcaa gggagattct tctctgcgct ggagggccag
     3061 ttgataaagt tcttccaact tggattcatc ctttttcaag agaaagactc ccgaacgctg
     3121 gtaaaagtcg attttttgtc ctgatttctc taaatcagct aataaatcca cataaaaatc
     3181 agcccccaag cgcgccatct tgtaccaggc tttattacgg cgtttggaaa accaaggact
     3241 gataattcct gctgcggcct tggtggcttg accttgctca tggtcaaaaa cggtcacctc
     3301 taggtcactt tctctcgaga ggtagtaggc agctgttgct cccacaattc ctgctccaat
     3361 aatggcaact tttttcattg tcttcacttt ctaactagat atgacggaaa ggattggtcg
     3421 atgcttgact aggtaaaatc tctagttccc agcctttttt ctctttccat tgagtaagga
     3481 gtgctgcgat tttttccaca aaaagcactt cgatatagtg acctggatcc aatgctaaca
     3541 agccatcaga cagcatatcc tgagcagtat ggtagtagat gtcgccagtg atatagacat
     3601 ctgccccctt tgccaaagca tccttataga aagactgccc gcttccacca caaattgcta
     3661 ctcttgaaat aggcttctgc aaatcattct cttgataatg caccattcga aggctatcta
     3721 ggtcaaagac ttgcttgacc tgttgggcca attcccaaaa tgtctgaggc tgaatattcc
     3781 caatacgtcc aattccacgt tctggacctg tttcctgcag ataagtcgtc tcctcgattc
     3841 ctagcatctg acaaaaccag tcattgagcc cattttcaac gatatcaata ttggtatggc
     3901 tgacataaac tgcgatatca tgcttaatca ggtcgatgta aatctgattt tgcggacggc
     3961 tggcaagcaa gtccttgata ggacgaaaga taggcgcgtg cttgacgata atcaagtcca
     4021 cacccttttc aatggcctct gccaccgtct cttcacgaat atcgagggca accatgaccc
     4081 tttggatacc cttgtctaaa gtgccaattt gcagaccacg gctgtctccc tccatagaaa
     4141 attcctgagg gcaaaaggct tcataagctt ggatcacttc acttgctaac atggagcacc
     4201 tccttgatag cttgaatctt atctactaga acttgacgtt cttccagatt tttttctggg
     4261 atttgtccga gggcgaactc tagcttctca gcttcttttt gccatttttg gacaaatact
     4321 ggactgactt ctttggacaa gaagggacca aagcgaacat cactggctga tagcttcatt
     4381 tgtcctgctt ccaccaccaa aatctcataa aactttccag cttcttctaa gatgctttct
     4441 gctacaatct ggaatccatg atcctgtagc cagatacgca agtcgtcttc acgattattg
     4501 ggctggagga tcaaacgctc tacattagct aacttcccca aaccttcttc taaaatccta
     4561 gcaatcaaac gaccacccat gccagcaatg gtaatgacag acacttggtc agtctcttca
     4621 aaagctgcca agccattggc taaacggact tggattttct cctttaggcc gtgagcctca
     4681 acatttttaa ccgcagactg atagggacct tccaccacct cacctgcaat agcgcttttg
     4741 atttggcctc tctcaaccaa ctcgataggc agataagcat ggtcacttcc cacatctagt
     4801 aaaatagccc cctgtgacac aaaggaagct accaattcta atctctttga aatcatcttc
     4861 tctcactttc caaaactcta ttacctctta ttataccaca tttcaatctt caacttccca
     4921 gtaatataag cacctctggc gaaagaagtt tcaatgtcct aaagtaataa gtgaatccaa
     4981 ttgaaagatt ttaaacaatt tgcaaaaatg tcaaaaaata aaaaataaac agtttattca
     5041 gaaaattctt gacatataaa aacacatggt agaatataat tagaaagtta gaaaaaataa
     5101 aagtttgact aaaatttgta tttgaaggtg gtgttcagat aagaaattta gtcagacgaa
     5161 ccacgaattt gctctatgct ttctggaatt tatcataaca ggaggataca gtcatggaac
     5221 aaacattgtt tgaattagaa ctacttccag aggaagatgt cattgtcaca ggtctcccta
     5281 agtattgttc ttttacttgt ttaattacag gtcgctagtt atattttata taaaataagt
     5341 agctttactt acggaatagg ctagtgctgt gtctctagcc tattttaata attaggagtt
     5401 tgttatggat ttattagaga aagaatgttt aaaatgtgat aaaaatttcc aacagggtga
     5461 tatttggaat tactattatt tatcagataa ggtgcctgca caagggtgga aaatacacat
     5521 aagctcccaa ataaaagacg ctgtaaatat ttttaagatt gtgtataaac tatcccaact
     5581 aaataattgt agctttaaag tcgttaaaaa tttagaggaa ttaaaaaaaa ttaattcccc
     5641 tagggaaatg agccctactg ctaacaaatt tataactcta tatcctaagt cagaatctga
     5701 agctaagagt atgatttgta atcttacgaa tagactgtca gaatttaagg ctccaaaaat
     5761 actatctgac tatcaatgtg gaatgcattc tctagttcat tatagatatg gggcttttta
     5821 aaaaaaacaa gcttatgatg aaaaaaataa aaaagtcatc tatttattgc tagatgaaaa
     5881 aaggaagaac tatgtagaag ataagagaca aaatttccct agtctcccta actggaaaat
     5941 ggatttattt tcagaagaag aaaaaaggaa ttattttcaa accacatgtg aaatttcaag
     6001 taaagactct gcaataaata aatacaaaat ggaaaaaatt attaagagat caaataaagg
     6061 aaatgtttat cgggcaatta gaaaatcgga cgggcaaaaa gtaatcatca agcagtcaag
     6121 accttttgtg aattatgatg ctgaaggaga atggacagct cttgatgata taaaaaatga
     6181 agctcacatg ctaaaaaaat tagccgataa aagttatact actaatttaa ctgatgaatt
     6241 ttatatcgtg gatgattatt ttcttgttca ggaacaagtt gacgggttaa actttgaaga
     6301 atttattcga gaaacagaac actccttaaa tattagagaa aaaacactgt ataacattgt
     6361 gaatatagta agtgacatcc ataaactggg aatataaaat tgtagatata gctcctacaa
     6421 attttatata taccaaaaat gtactgcacc ccaaaagtta gacaattaat ttatccgaag
     6481 gatttagttc tgtactgcac aaggctaagt ccttttagtt ttaccttaat tcgtttgttg
     6541 ttgtagtaat caatgtagtc cacaatagct tgttcaaggt tttctaaaga tctaaagttc
     6601 ttctcataac cataaaacat ctccgatttc aaaatgccaa agaaagattc catcatgccg
     6661 ttgtctgggc tgtttccctt gcgtgacata gatgcttgaa ttcccttact ctctaggaac
     6721 cgatgataag aatcgtgttg atattgccag ccttggtcac tatggagaat catattctca
     6781 tagtgcttct ctgtgaatgc ctgttccaac attgtttgta cttgttctaa gttgggtgaa
     6841 gttgaaagat tataggcgat aatttcgcta ttaaagccat ctaaaactgg taataagtaa
     6901 agcttttgag tacttgctgg aatggcaaat tctgtcacat ctgtgtagca cttttccatt
     6961 gttttagagc cttcaaattg gccttgaatg agattctctg ctttcttacc aacgtctcct
     7021 ttatgagaag aatattttcg tttttgtcgc attttagctt gtaaattgag tacttttatc
     7081 aagccttgaa ctcttttatg atttaccaga taaccacgat ttcttagttc taaataaatc
     7141 cgacgataag cataatttcc cttgtgttcg ataaaaatgg attgaatttc agctttaagc
     7201 tcttggtcct tatctgtttt atctagctgt ttcaagtgat agtagtaggt ccaacgagct
     7261 agtttaatgg cttttagaag aagatctaac gaaaactcag tcattaattc ttgaacaatt
     7321 tctgtctttc ttctttctct ttttcctcct tcaatcggag ttctcttaac ttttttagga
     7381 tggcattctc cgctctcagg tactcatttt ctgcttgaag atgttctaat tctgtcctct
     7441 cttcaggtat cgtttttggc ttacgtccca ttttaggtac tctccctctt gttttctcaa
     7501 caatagtata cccgtttttc ctgtattgtg ctagccagtt aagaagtatc gtacgacttg
     7561 ggagaccgta ttcaa
//
LOCUS       DAVKZI010000066         7438 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKZI010000066 DAVKZI010000000
VERSION     DAVKZI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.067"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            25..870
                     /locus_tag="VXB18_002005"
     CDS             25..870
                     /locus_tag="VXB18_002005"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0383149.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1017..1719)
                     /locus_tag="VXB18_002006"
                     /pseudo
     CDS             complement(1017..1719)
                     /locus_tag="VXB18_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2067..4391
                     /gene="pflB"
                     /locus_tag="VXB18_002007"
     CDS             2067..4391
                     /gene="pflB"
                     /locus_tag="VXB18_002007"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0383150.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(4449..5711)
                     /locus_tag="VXB18_002008"
     CDS             complement(4449..5711)
                     /locus_tag="VXB18_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0383151.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGAFPSLIRLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFIRYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGY
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(5976..>7438)
                     /gene="rlrA"
                     /locus_tag="VXB18_002009"
     CDS             complement(5976..>7438)
                     /gene="rlrA"
                     /locus_tag="VXB18_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEV0383152.1"
                     /translation="RSIELDELSTLTSLQSKSLLSILQELQETFEEELTFNLDTQQVQ
                     LIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQSFNEFTQKEYISIATGYRVRQKC
                     GLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFGIEIYDLNDGSMDWVTHMIVQSNS
                     QLSHELLEITPDEYVHFSILVALTWKRREFPLEFPESKEFEKLKNLFMYPILMEHCQT
                     YLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWNQEKKTHTIQLILQHTRGKHLLSK
                     FKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVPYYNYYEHYGIESDKPLYHISKAI
                     VQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLPAIPIFIILNNQADVNLIKSIILR
                     NFTDKVASVTGYNILISPPPSEEHLTEPLIIITTKEYLPYVKKQYPKGKHHFLTIALD
                     LHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYLL"
BASE COUNT         2212 a         1379 c         1516 g         2331 t
ORIGIN      
        1 taaatataat ataaggagaa atatatgtat cttattgaaa ttttaaaatc tatcttcttc
       61 gggattgttg aaggaattac ggaatggttg ccgatttcca gtacaggtca cttgatttta
      121 gcagaggagt ttatccaata ccaaaatcaa aatgaagcct ttatgtccat gtttaatgtc
      181 gtgattcagc ttggtgctat tttagcagtt atggtgattt attttaacaa gctcaatcct
      241 tttaaaccga ctaaggacaa acaggaagtt cgtaagactt ggagactatg gttgaaggtc
      301 ttgattgcca ctttgccttt acttggtgtc tttaaatttg atgattggtt tgatacccac
      361 ttccataaca tggtttcagt tgctctcatg ttgattatct acggggttgc cttcatctat
      421 ttggaaaagc gcaataaagc gcgtgctatc gagccaagtg taacagagtt ggacaagctt
      481 ccttatacga ccgctttcta tatcggactc ttccaagttc ttgctctttt accagggact
      541 agccgttcag gtgcaacgat tgtcggtggt ttgttaaatg gaaccagtcg ttcagttgtg
      601 acagaattta ccttctatct tgggattccc gttatgtttg gagctagtgc cttaaagatt
      661 ttcaaatttg tgaaagccgg agaactcttg agctttgggc aattgttttt gctcttggtc
      721 gcgatgggag tagcttttgc ggtcagcatg gtggctattc gcttcttgac cagctatgtg
      781 aaaaaacacg acttcaccct ttttggtaaa taccgtatcg tgcttggtag tgttttgcta
      841 ctttacagtt ttgtccgttt atttgtataa gaaaaacctt gaaggggcaa ctcttcaagg
      901 ttttatactc ttagaaaatc tcttcaaacc gcgtcagctt tatctgcaac ctcaaaacag
      961 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagctttaa
     1021 aatccagtca gggtaatccc caataggcgg acacctcttt ctttctcgct taattcttca
     1081 tagagttgca gggctatttg gcttatctga ctagcatctt gtgttttttg agcaagactt
     1141 tttcgtttgg taagagttga aaagtcctcg tagcggattt tcaaaatgac aatttttcca
     1201 gctttttctt gttgatgtag attgagagcg actttttctg atagaagagt cagctctttt
     1261 ttgatatctt cctcagcacg gagaatcttc ccgtaggttt tctccttgcc gattgattta
     1321 cggatgcgat tggatttgac tggagagttg tgaatgccac gagcctttcg atacagatca
     1381 tagcctagtc taccaatctg tatagcgctt aaaaatagct cgaatctgga gtcccacaga
     1441 cttgtatttc tcataattcc ctgagataaa gacagcctgg ggacaacgtt cataagcttc
     1501 cttggaactc atggcagaat ggacaccaaa agctcttgcc tcataactac aggtagaaac
     1561 gactccccgt ccacctgttt gccgagggtc gcttccaata atgacaggtt ttcctctgag
     1621 tttaggatta tccctgattt ccactgcagc aaaaaaggca tccatgtcaa tatggatgat
     1681 ttttcttgac aaatcattta acaaaggaaa aatcaacatg cctagcacct ttttatactc
     1741 ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaac ctcaaaacag tgttttgagc
     1801 aatctgcggc tagcttccta gtttgctttt cgatttccat tgagtgttac tgcttatttt
     1861 cttttattat accctttttt ctgaaaaaaa gaaaaaagga ctttattttt tcaaaaatat
     1921 aatacagttt gaaataaaat atagactgtt ttagaaaaga aagtgtaaaa atagggaatt
     1981 ttcacttgtt gaaatcggtt actatatggt atacttgtct tatgaatgta acagatgact
     2041 gttactagaa aaaagaggac attaatatgg ttgttaagac agttgttgaa gcacaagata
     2101 tttttgacaa agcttgggaa ggcttcaaag gcgtagattg gaaagaaaaa gcaagtgtat
     2161 cacgatttgt acaagctaac tacacacctt atgatggaga cgaaagcttc cttgcaggac
     2221 caacagagcg ttcacttcac atcaagaaaa ttgtagaaga aactaaagca cactacgaag
     2281 aaactcgttt cccaatggac actcgtccaa catctatcgc tgatatccct gctggattta
     2341 tcgacaaaga aaatgaagtt atcttcggta tccaaaacga tgaactcttc aaattgaact
     2401 tcatgccaaa aggtggtatc cgtatggctg aaactacttt gaaagaaaat ggatacgaac
     2461 cagacccagc tgttcacgaa atcttcacta aatatgtaac aacagttaac gacggtattt
     2521 tccgtgccta cacttcaaat attcgtcgcg ctcgtcacgc acacactgta actggtcttc
     2581 cagatgcata ctcacgcgga cgtatcatcg gtgtttacgc acgtcttgct ctttacggtg
     2641 cagactactt gatgcaagaa aaagtaaatg actggaatgc aatcaaagaa atcgatgaag
     2701 aaacaatccg tcttcgtgaa gaagtaaacc ttcaatacca agcattgcaa caagttgttc
     2761 gcctgggtga cctttacggg gttgatgttc gcaaaccagc gatgaacgtg aaagaagcaa
     2821 tccaatgggt taacattgct ttcatggctg tctgccgtgt gattaacggt gctgctacat
     2881 ctctaggtcg tgtaccaatc gtattggaca tctttgcaga acgtgacctt gctcgtggta
     2941 catttactga atcagaaatc caagaattcg ttgatgattt cgttatgaaa cttcgtacag
     3001 ttaaatttgc tcgtacaaaa gcttatgacc aattgtactc aggtgaccca acctttatca
     3061 caacttctat ggctggtatg ggtaacgacg gtcgtcaccg tgttactaag atggactacc
     3121 gtttcttgaa cactcttgac aacatcggta actcaccaga accaaacttg acagttcttt
     3181 ggactgacaa attgccatac aacttccgtc gctactgtat gcacatgagc cacaaacact
     3241 cttctatcca atacgaaggt gtaacaacaa tggctaaaga cggatatggt gaaatgagct
     3301 gtatctcatg ctgtgtgtct ccacttgatc cagaaaatga agaacaacgc cacaacatcc
     3361 agtacttcgg tgctcgtgta aacgttctta aagcccttct tactggtttg aatggtggtt
     3421 acgacgatgt tcacaaagac tacaaagtat ttgatatcga accaatccgt gacgaagttc
     3481 ttgaatttga atcagttaaa gcgaactttg aaaaatctct tgactggttg actgacactt
     3541 acgtagatgc cttgaacatc atccactaca tgactgatag gtacaactac gaagctgttc
     3601 aaatggcctt cttgccaact aaacaacgtg ccaacatggg attcggtatc tgtggatttg
     3661 ctaacactgt tgatacattg tcagctatca aatacgctac agttaaacca atccgtgacg
     3721 aagatggcta catctacgat tacgaaacaa tcggtgacta cccacgctgg ggtgaagatg
     3781 acccacgttc aaacgaattg gcagaatggt tgatcgaagc ttacacaact cgtctacgta
     3841 gccacaaact atacaaagac gcagaagcta cagtatcact tttgacaatc acatctaacg
     3901 ttgcttactc taaacaaact ggtaactcac cagttcacaa aggtgtatac ctcaacgaag
     3961 atggttctgt gaacttgtct aaacttgaat tcttctcacc aggtgctaac ccatctaaca
     4021 aagctaaagg tggttggttg caaaacttga actcactttc tagccttgac tttagttatg
     4081 cagctgacgg tatctcattg actacacaag tatcacctcg cgctcttggt aagactcgtg
     4141 atgaacaagt tgataacttg gtaacaatcc ttgatggtta cttcgaaaac ggtggacaac
     4201 acgttaactt gaacgttatg gacttgaacg atgtttacga aaaaatcatg tcaggtgaag
     4261 acgttatcgt acgtatctct ggatactgtg taaatactaa atacctcact ccagaacaaa
     4321 aaactgaatt gacacaacgt gtcttccacg aagttctttc aatggatgac gccttggatg
     4381 cattgagcta atcaagttct tgaataataa aaagggctct ttgtcaactg tagtgggttg
     4441 aagaaaagct aagctcgaga aaggacaaat tttgtccttt cttttttgat gttcagagcg
     4501 atgaaaatcc gttttttgaa gttttcaaag ttccgataac caaaggcatt gcgcttgatg
     4561 tctttgatga gtttgttagt ggcctcaagt ttagcgttag aataaggcaa ttcaatggcg
     4621 ttagtgatgt agtttttata gcgaataaat gtgctcaaag tggttttaaa ggtgcggttg
     4681 agatgaggta acgtgtcttg aattaagccc caaaactggt cagtattctt ctcttgtaga
     4741 tgaaatagga gtagttgata caggtcatag taatctttaa gttcaggtac tagagtaaag
     4801 attttcttca gacactccct aggagttaag gtctctctga aagttctagc atagaaaggc
     4861 ttaagagaga gtttccgact atcttttagg ataaatttcc agtaatattt aagagctctg
     4921 tattccagag atttatcatc aaattgcttc atgatgttga ttctagtctg attaagagcc
     4981 ctgctcatgt gttggacaat gtggaaacga tcgagaacaa ttttagcatt gggaaataat
     5041 ttcttaatga gagggatata acttccagac atatcaacag tgacgacttt aacttttttt
     5101 ctagcttctt tcgagtactt gaagaaatga tttcggatgg ttgtttgacg tctgttatca
     5161 agaatggtca tgattttctt agtgttgaaa tcctgagcaa tgaaagccaa tttccccttc
     5221 tggtaggaga attcatccca ggagaggatt tcaggcaaag tggtgtaatc ctcttggaaa
     5281 tgaaattgct tgagcttacg atagacggta gaggtagagg tagagatggc taatttagaa
     5341 gcgatatgtg taagagcctc tctgttgagt aggagttggg caattttctg tctcaccatt
     5401 tccgagattt ggcaattttt ctgaacgaga gttgtttcag ctacagtgac tttccgacag
     5461 gacttgcatt gaaatcgtct ctttttcaaa cgaatgaggc tagggaaagc accaatctcg
     5521 ataaaaggga ttttagaagg cttttggaag tcgtatttga tttgttttcc tttacagtgt
     5581 ttacatttag gtgggtgata atcaagtgta gcgaagactt cgatatgggt atcgtgctga
     5641 atggctttat ttaaggtgat gtttttgtct tttattccga tgagtaatgt ggtatgattg
     5701 atgtgttcca taagatactt tctaatgagt tgtttaggcg cttttcatta taagtcttat
     5761 gggacttttt tgatactcaa aaagccctat aatctccaca gtgggattta cccactacag
     5821 aaattataga gccagaaaaa acacttttgt tcactagcag aaactagaga gcagaagtgt
     5881 ttttctgttc agatttaccc aaaactggga aatatgggga taagaataga gatggcttag
     5941 gaagcccctt tttgtgtgta gacagtacga tgaacttata acaaatagtg agccttttta
     6001 gcaatcattg cgacccgttt gtcaaaagcc tcttttcgga tatctacaat tgtctgatag
     6061 atgagacgct gttggctaac atgcaaatct aaggcaatcg tcaaaaagtg atgtttccct
     6121 ttgggatact gctttttaac gtaaggcagg tattctttcg ttgtaataat aatcaatggc
     6181 tctgtcaaat gctcctctga aggaggagga ctaattagaa tattgtatcc tgtaacagag
     6241 gcaactttgt cagtaaaatt ccgtaaaata atggacttta ttaagtttac atctgcttga
     6301 ttatttaaaa tgataaaaat cgggatagca ggtagtgagg aaaagatggt ttctgtcaag
     6361 tagagtgaga aaaggtacag ccgatgctgg tcgataactc cttcaatctt ctgctcagtc
     6421 atccactctt gaacaattgc tttcgaaata tgatacagtg gcttgtcgct ttcaatccca
     6481 taatgttcgt aataattata atagggaact agattttgta aaccaaacaa aaacgttctt
     6541 gttaagaaag tcagtgctgt taaaaaagaa agagaattcg aaatgtcatt tcctaagata
     6601 ttcttgaact tggatagtag atgctttcct cttgtatgct gaagaatcag ttgaatagta
     6661 tgagtctttt tttcttgatt ccatttgtcc ttggaaaacg aagaattagc agaacaataa
     6721 accaaaaaga tataatccag ttcttcctga gtaaaagtca tgttggcatg tggctctaag
     6781 taagtttggc aatgttccat caaaatcgga tacataaaga ggttttttaa tttttcaaac
     6841 tctttggact cagggaactc aagtggaaat tcccgacgtt tccaagtgag tgccactagt
     6901 atgctaaaat gaacatactc gtcaggtgtg atttctaaca gttcatgact gagttgagaa
     6961 ttagactgca caatcatatg tgtgacccaa tccatacttc catcattcaa atcataaatc
     7021 tcaataccaa aatgaaactg gaggagtgca attaaaaaac gaatgcgata ttcaggacca
     7081 actacttgat ttttcacaag gtccaaacct actgaacgta gtaacaagcc acacttttgt
     7141 cgtacgcggt agcctgttgc gatggaaata tactcttttt gtgtaaattc gttaaagctt
     7201 tgattacctt gtagtagaaa gaagcggagt atttttaaaa tagttgattg gttataaagc
     7261 tgatggaagt aataattcgt ttgatgagaa tggtgttcga ttaattgaac ttgttgcgta
     7321 tctaaattaa atgtcaactc ttcctcgaat gtttcttgta attcctgcaa aatgcttagg
     7381 agacttttag attgtaatga agttaaagta gacagttcat ctagttcaat agaccgaa
//
LOCUS       DAVKZI010000067         7416 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKZI010000067 DAVKZI010000000
VERSION     DAVKZI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.068"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(87..1502)
                     /locus_tag="VXB18_002010"
     CDS             complement(87..1502)
                     /locus_tag="VXB18_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0383153.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1515..3353)
                     /locus_tag="VXB18_002011"
     CDS             complement(1515..3353)
                     /locus_tag="VXB18_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0383154.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3371..4210)
                     /locus_tag="VXB18_002012"
     CDS             complement(3371..4210)
                     /locus_tag="VXB18_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0383155.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKKALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4510..7188)
                     /locus_tag="VXB18_002013"
     CDS             complement(4510..7188)
                     /locus_tag="VXB18_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0383156.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFNGDSEFFLCKRLKDKSQFVMERS
                     QFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKSFINDQGKIQYFPSYDCGWKQLL
                     PEKRSFQTLTDSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQVRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKVLREDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYGAMPLLGKVDEMTILRLESASIASELVAGLR"
BASE COUNT         2430 a         1556 c         1032 g         2398 t
ORIGIN      
        1 gaatttgatg tcttccaaac ctctttattt catatttaat gagatgttgc cttaaccgtg
       61 ataatatcta atcatcaata aacaaactat ttgaataagg attctccatt tgattcaatc
      121 actcctttat accaagtaaa ggacattttc ttatatcgat tgaatgtgcc atttccatca
      181 tcatttcgat caacataaat gagaccgtac cttttagaaa gttgtgcagt ggacatagaa
      241 acacagtcaa tacatcccca agacgtatag cccataattt caacaccatc ctgtagagct
      301 tcagcaactt gcaataaatg ttctttcata tactgaattc tataatcatc ttggacggtt
      361 aagttattaa gttcatcttt tattagttga tctttagcac ctaatccatt ttctactata
      421 aataatggga tttgataacg gtcataatat ctatttaaaa ttatacgtag tccaattgga
      481 tcaatttgcc atccccactc tgaagactct aaataaggat ttactaaacc accaataata
      541 ttcccttctc ctgaattata ctgtgttgga atagcagatt gagtcacact catgtaatag
      601 ctaaaggata aaaaatctac agtataattt tttaataact ctgcatcttc agctgcaaac
      661 tctatgttaa tgtcattttc cttaaaatat ctttttgcat aattcggata ataacctcta
      721 acatgcacat ctgaaaatag ataatttaga ttctcatact catgagtcgc ccatacatct
      781 tttggatttg gagtcattgg ataagctggc atagctaata ccatacatcc caccttaaac
      841 tctgaattaa tctcacgagc aatttttgta accaaacttg aggcgactaa ttcatgatgt
      901 atagcttgat ataattcttg tttcgaaaga ttctccttag gtatatctat tcctccacta
      961 gtaaatggta attccaaaac agagtttact tcgttaaatg taagccaata tttaacttta
     1021 tctttatacc tttctaaaac tgttcgagca aatttttcat aaaaatgaat cattctccta
     1081 tcaacccatc catgatattt tcttgctaaa tataatggag tctcatagtg tgaaagagtt
     1141 acaagtggct ctatcccgtg agcatgtagt tcatcaaaca attcatcata atatttcaaa
     1201 ccagcttcgt taggttcttc ttcatctcct tttggaaaaa ttctactcca tgcaatagaa
     1261 gtacgaaaaa cattaaagcc catttcagaa aacaaggata tatcttcctt atatttatga
     1321 taaaaatcaa tacctatcaa ttttaagtta tcttctgtag gattttctgt tgcttctcct
     1381 aatccacctt tgggtaacac atcctgaact gataagccct taccatcttc attatatgct
     1441 ccctctactt gattagctgc aacagctcca ccccaaagaa aatcatctgg aaaaatggtc
     1501 ataactttcc tccattataa tattaccagt aattccttag aatgctcgat tgtctgatta
     1561 ttaggtaata ctaatacatc tagaaaatca ttggtattcg ttacaattac tggtgtaact
     1621 gtttcgtagc ctttagtctt gattaaattc aagtccattt caaaaatcaa ctgatttttg
     1681 aaaactctgt ctccttcttc tacatgacta ataaaacctt gaccttttag ctcaacagta
     1741 tctaatccaa tatgaattag taactcaaca ccctcatcac tcttcaatcc aattgcgtgc
     1801 ttagtcggaa aaatatttgt aattttccca tcaaatggtg cataaacctt accttcactt
     1861 gggataatcg ctactccgtc tccaattagt ttatctgaaa atgttttatc ctggacatcg
     1921 cttaacggaa tgatttctcc tgatatagga gaaaatatca tttttttatt tgaaactcca
     1981 gctttaactt ctaaattgct agaactctct tcttcatcga ttccaaatat ataagctaat
     2041 acaaaggtaa taacaaccga aatgaccgcc acaattaaag catttacaat atttgatggc
     2101 acatcagaat aaataaattg aggcaacgct atcaaagatg ggacagcaaa tagatatgct
     2161 ttaacactag taagacctgc aaataatccc gctaatccac caccaatcat agctgcataa
     2221 agcggttttt tatattttaa agtcacacca tataatgcag gttcggtaat ccctgcaagt
     2281 aaggctgaga aacctgctgc aaaagcaatt tgttttgtat tattattttt actctttaat
     2341 gcaacagcca tcgaagcagc cccttgagct aagtttgacc ctaacattgc tggaagaatt
     2401 aatacgtctg gagtagcaat agatgccgcc aaaaaaatag gtgcaaaagc ccaatgcatt
     2461 ccagtcataa caataaatgg cataatagca ccaagaatag ctaatgtaag ccatccagct
     2521 acaccataca tttgcccaac tagatttgat aatccttcac caacaattac tccaataggt
     2581 ccgactacaa ctaaggcaat acagcttgat actaataata ctagcgtagg ttgcaaaaaa
     2641 ctcttagtaa cagctggtgt taatttagca atcatttttt caatatattt catcaaccaa
     2701 accataataa gaattggaac gactgacgaa ccataactag ctggtgtcac aggtgcacca
     2761 aataaactaa gaggattccc tgattgcacc atttgaacaa aatttggatg gagaagtaca
     2821 cctgctacag acatagctaa tgtagatgtt acttttaatt tttgtgatgc agaataagct
     2881 aataacagcg gtaagaaata atatggagca tccccaaaaa atgtcaaaaa agcaatagtc
     2941 tgagaatctg attgcaatat accaagcatt ggtaaaataa ttaccaagac tttcagcata
     3001 cctcccccta acattgctgg aatgattgga gtcatggaac cagcgatata ctcaatgatt
     3061 ctttctaaaa tattcccttt gtgcccttga acaactgaat cggattcaaa attgccaagt
     3121 ttaacgaatt ctttataata attagctaca tcattaccaa gtataatttg atattgtcca
     3181 ttctttttca taatacctat tacacctggt atcttcttca catcatcatc attgactaaa
     3241 ttttcatctt ttaattctaa tcttaaacgt gttacacaat gggtaactct attgacattt
     3301 ttttcacctc caattacatc gaggattttt tgtaccgtat ctttataact catggtattc
     3361 tcctattcta ttaatctaaa ttttttgtta agcgacgaat atgagccatc aaataaacta
     3421 attcactaga agtcagcaaa taattgtact cagtttgtat aaacattgcc acctgttcac
     3481 cacattcata ttctctagga tatttatttt tcattaatgc taacaagtct tcatcatcat
     3541 cgtcacaata agttgtattt tcaaccaagc gatgggcaaa taattttata tgagttatga
     3601 atctataata atcaatagaa tcttggttaa actcagtaca atagaaatct tgaatgattt
     3661 tctcaattcc cataattatt tcagtgattt tatacgactc ttgaaaatta ttttctaaat
     3721 tagcattaac aaaatgtagc gctatgaatg cagcttcgtc aattggaagt tcaataccta
     3781 actctttttt tattatttgt aaagcctttt tcccaagctc aaattcttct ttataatatt
     3841 tcgagatttc ccagcgtagg ggattcgaaa taataactcc ttctttataa cgttctatac
     3901 tcgaagaaat atgatccgtt agatttatat agataatctc atcaaaatta ttacccaatg
     3961 ttattttacc taggttaatt attttttcgg tgatgtacac caactccaaa ggaacgttaa
     4021 taaacatctc tgtaaaacgg gtcatattat ctctattttt gagaaaaaaa cttttctcaa
     4081 tatcaattgg atttacttta tctccaattt ttcttccaaa agctattccc cttccaaaaa
     4141 gaagaatatc gatatctttt ttactttgcg caattacggc attgtggttt agtattcgtt
     4201 ttatgatcat aaaatttccc ttttaaaata aaaggaacct acttaaaaaa catcaagaaa
     4261 cttcttctga tgtgattaaa taggttcctg ctcacttgta ttagtgataa catcctttta
     4321 tttcaatttt taatggtgac atgaagctta aataattaat aactctgtaa ccgtttttat
     4381 tttatgatat ttcaatctat ttgtcaagta cttatagaaa tttttttatt ttgtgtgctt
     4441 cgaatgtgac aatggcaaca gtctcactaa aaaacgaaag tcatacatag aaatttttaa
     4501 aaattttctc tatcgtaaac ctgccactag ttcagaagct atactagctg attccaaacg
     4561 tagtatggtc atttcatcta ccttccctaa taatggcatt gcaccatacc aaacaatagt
     4621 cttattcacc aaaagaatag gcgttactat ttttgattga gtaaaagaca ctttaatttt
     4681 ctggctcttc aactggtcta gccatgcttt atttgcaacc gtctctggta tacatatctc
     4741 aatttgacta atcctaaatt cttttagaaa attcatcagt tttgtctggt gcacataagg
     4801 taaaataagc agacattcct gtctttcccc tgctaagtcc tctctcaaca ccttctcata
     4861 tctactatca acataaacga attgtttctc ctcaccctcg atgacacgat aatccatctt
     4921 tcgataagct acttgtcgtt tctgaaacat cttttctaaa taaggaacat gaatatccac
     4981 ataatcgaaa atacgcacca aagacttatc cttgtagttt ctatgaatcc gacctgcata
     5041 ctgaattaaa ttatttttcc aagaaaaggg tgctgccaag ataagcgtgt ccaactgagg
     5101 taagtcaaaa ccttcgccaa tgtattttcc agtagacaac aaaacaaacc ctttatctaa
     5161 ctgttctaac gtctccagta aactcgttct ttctcggact ttggtttttc cgctaataat
     5221 gtaacagtca tcaacctctt tctctttcaa taacttttca aagacatcta tctgttgaat
     5281 tcgattaact aaaaccaaga tattccgtcc ttctgccact tgggctagaa tatccttgag
     5341 aatcaactga ttcctcgctg agtcagtagc aatccaatca ctaagctgta taaaattact
     5401 tgctttggtc ttttcaatct ccaaatgacc aaaagaagtg aatcttaatt gcaattgccg
     5461 tttaaaatcc gtttccctct tatcagcagt atggagtatc tcaccaattc tctgaaaaac
     5521 aataggctca tgaccattct tacgctcagg cgtagccgtc aaaccgtaaa gatacttccc
     5581 tctaaactga gcaacaactt tttcaaacat caaggcagag acatgatgac actcatccac
     5641 aatcatcatc tcatactcat ccaaaagact ttgactattt tccaacttaa atagagattg
     5701 aatcataacg acatcaacca gtttactcag ccatttctta gtcccaccgt actgtccaac
     5761 atagccgatt accttttcac gacctgatgc cgtataacgg atagcctcct cctcttcgaa
     5821 agtcaaaaag cagtttaagc gatctagcca ttggtctaag agttgcttat tatggactag
     5881 aataattgtt tttgttttcc gttcagagat aagagcagca cctaaaacgg tcttcccaaa
     5941 accagtctcc gcatgaagta aaccattttc tttagaagtc atatctgaca gggctaactc
     6001 ttgctcaaaa gtgagttctc ccttaaattc cacgctaata gacctttgta cctttctcct
     6061 atcttccaca gatacctgct taaatttatc ttgcaatgga tacagcaaac ctcttggcaa
     6121 ccataaataa tgatcggatt ctccaaataa atacattctc tcaggaattt gataggttgg
     6181 ctgtcgcata gcctgcttta aataaaattc gggattagaa aatgaagcca tatttttcaa
     6241 gaaaaacagt gtcttgggtg tcacagacga tttttcaagt tggatcatat tggataagac
     6301 gatcttcaac tccttgtcca attcttgctt gcctaactct tcttggatta acagtgccac
     6361 tttagcagtt gaaaccctct gaatttcttg tagatacctc cattggtctt cataaggctg
     6421 aaactgttca tccacaaaga ccgttcgcac ttgatggtaa gcttctcctt gaaaaggcaa
     6481 ggcaatcaaa tttccaaatc cccccttagg aaggacatcc tgatttggaa acatgcgatc
     6541 aaaagaatca aaggacagtt gcatactttc ctgcattgcc agttctatca gtttctttcc
     6601 aaacaagcga gcctctcgac tcggaatcgc ttcctcaaag aagaaccaaa tatggagtcc
     6661 gtgacccgaa cgagaaatct ctaaatgggc ttccatctgg cgttccctgg ctattcttcg
     6721 aatggttaaa ccagcttctt tccaatctcc ttcatcaaaa tccagtacca aaaaatgaca
     6781 gctatcatct aagtgcatag gaaagatacc gatagctgtc tccccacgaa aatgagattt
     6841 caaaacggaa tccgtcaatg tctggaaact ccgtttttca ggtagcaact gcttccaacc
     6901 acaatcatag gaaggaaaat actgaatttt cccttgatca ttgataaaac tcttagcata
     6961 aacatcataa cggccagcaa acacagaggt aaacaattgt aatttttctt gcgtcgtcaa
     7021 gcgactactt tgaagttgga acatctcctc gaactgagag cgttccataa caaactgact
     7081 cttgtcttta agacgtttac acaagaaaaa ctcactatcc ccattaaaag aagaaaagac
     7141 atcaagtact tctaccacaa ttccatccaa agacacaaaa acagccataa gagtcacctc
     7201 cttgattcct ataggctgat tataacaaga atagctgaaa ttgtacacga aaataaaatc
     7261 ctaatagtac tcattttgta tgtggctaat attccgtctc gctccggaat gtacgaggta
     7321 aatagagttt aaacgagcag tctataaaat tcaaaaaacg catcatatca ggtgtacatg
     7381 aactacaccc caaaagttag acagaaaaaa tctaac
//
LOCUS       DAVKZI010000068         7366 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKZI010000068 DAVKZI010000000
VERSION     DAVKZI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.069"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..99
                     /locus_tag="VXB18_002014"
                     /pseudo
     CDS             1..99
                     /locus_tag="VXB18_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(236..1204)
                     /locus_tag="VXB18_002015"
     CDS             complement(236..1204)
                     /locus_tag="VXB18_002015"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0383157.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1349..2129)
                     /locus_tag="VXB18_002016"
                     /pseudo
     CDS             complement(1349..2129)
                     /locus_tag="VXB18_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2154..2651)
                     /locus_tag="VXB18_002017"
     CDS             complement(2154..2651)
                     /locus_tag="VXB18_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0383158.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2724..4085)
                     /gene="radA"
                     /locus_tag="VXB18_002018"
     CDS             complement(2724..4085)
                     /gene="radA"
                     /locus_tag="VXB18_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0383159.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSININRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4099..4614)
                     /locus_tag="VXB18_002019"
     CDS             complement(4099..4614)
                     /locus_tag="VXB18_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0383160.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4616..5059)
                     /locus_tag="VXB18_002020"
     CDS             complement(4616..5059)
                     /locus_tag="VXB18_002020"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0383161.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5116..5212)
                     /gene="ffs"
                     /locus_tag="VXB18_002021"
     ncRNA           complement(5116..5212)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXB18_002021"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5245..5712)
                     /locus_tag="VXB18_002022"
     CDS             complement(5245..5712)
                     /locus_tag="VXB18_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0383162.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5913..7199)
                     /locus_tag="VXB18_002023"
     CDS             complement(5913..7199)
                     /locus_tag="VXB18_002023"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0383163.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
BASE COUNT         2293 a         1825 c         1220 g         2028 t
ORIGIN      
        1 attccttatc ttgaaacgac tggtatacct actagaattc tccttagaaa gcgtcgattc
       61 aagtgctatc actgttcaaa aatgatggtc gctgaaactt ctgatgacgt acagtcatat
      121 ttcttctctt tttattatat cacagtttta aatctagctt tactagattc accgctacta
      181 tctatttatt cggaaaaaag acgaaaaaac ctgagaatca tctcaggctt ggtcattaaa
      241 tttttttctc aatatcgaaa agtggagaaa gtggtcgttt ttcatgaata cgtacgatag
      301 catcccctag gagatgagcg attgaaatct gctcaatctt atcaatcaaa cgctcttctg
      361 gaagatagat ggtatccaaa acaaccaatt tcttaatagc tgatttttgg atattgtccg
      421 tagcaggacc agaaagaact gggtgcgtac agcttgcata gacttcaaca gcaccagctt
      481 ccgcaagagc atctgccgca tgacaaatcg ttccagcggt atcaatcata tcatcaatca
      541 agatacaagt cttgccttca accttaccga tgatgttcat aacttcacta gtattcatct
      601 tatcaacgct acgacgttta tcaataatag cgatagatgt tttcaaaaat tctgccaact
      661 tacgagcacg agtcacccct ccatggtccg ggctgacaac cacatagtca gaaccaacca
      721 taccacgacg ctcaaaataa tctgcaatca gaggagcacc catcaaatga tccacaggaa
      781 tatcaaagaa tccttgaatt tgcgcagcat gcaagtcgat ggtcaataaa cgatccactc
      841 cagctacttc aagcatattt gcgacaagtt ttgaagtgat tggctcacgc gctctcgcct
      901 ttctatcctg acgtgcatac ccatagtaag gcatgacaac attgacagat tctgcactcg
      961 cacgcttcaa agcatctacc ataatcaaaa tttcaagcag attgtcattt acaggcgaac
     1021 tagttgattg taggataaag acgtgtttcc cacggattga ttcttcaatg ttgacctgaa
     1081 tctctccatc tgaaaattgg cgaacacttg atttccccaa ctctatccca atctcctgcg
     1141 ccacacgttc tgccaattct ttattagaag aaagggcaaa cagctttaaa tcagaaaaag
     1201 acatgatttc ctccggtata tatgtatcgc ttgtgctttt cacaagattt tccatctacc
     1261 attgtagcgc tttttgcact atttttcaat caaaaataaa agaagggcac catatttgta
     1321 cccttgcatc attcttttga aaaatattct aggtcatcaa ctcattgtgt ttctcaacaa
     1381 agcaataagc atgataaaaa ccatagagag caatagccgt aaccactgga atcgctaaag
     1441 gcaactctgt ttccaactcc acaaaaggag agttaaacaa gaagtgagtt cccaaggcta
     1501 aacctagaaa aataaggccc tgtttcttgc caaccttctg tcctttatag gctctgtaaa
     1561 gcaagtaaac acctactaca gctagacctg aaaaagtcca gtgagaggca attcctgaga
     1621 tgatacgctc taaaattcgc gaaatagtaa agtcaaagcc ctctggcaaa tccgtacgaa
     1681 tataaccaat atcctcaatc atttggaatc ccaaaccgga agcaattcca agtaaaaaca
     1741 aagattttaa ttttcgcaca ggaatcaaag ccaaaacaaa aacaagtggc aataatttca
     1801 agggttcttc taccaaatgt actatctggg aaaagaaccc ccagtaaatc atggatataa
     1861 gtattagcaa aactagacaa ccagcctgaa aggaacatcc ctcccaataa agacagaatc
     1921 aaaaccttct ttggcaattc ccattttttc ccaatacgga agagaaaata aagagccgga
     1981 atcatgtaaa agagagctag aaagatagaa actcccatta gtccatattc cgcacctgac
     2041 ctcgaaccgt ccgtatagta gatggtttca tactgtaaac caatacatag caataaaata
     2101 aaaataaata aaatactgct tttcttcata cactttcttt ctaaatgaag tatttataat
     2161 tctacgactg tcatacttcc tgtatcaaca ttgtaaatgg caccagagat aatgacatcg
     2221 tctggtatta ggggagactc gataagcagt tgcatatcct cgcgtacact ctcttctata
     2281 tcttggaagg gcaagaagtc ctggtctgac acatctacac ctaattcctc ttttaaatac
     2341 tcctgaaaag gttcattttc aaaggtctga gcaccacagt ctgtatggtg caataccaca
     2401 atctctcttg tccccatttg ttgctgggaa ataactagcg aacgaatcat gtcttcagtc
     2461 actcgaccac ctgcattccg caagatatga gcatccccaa gtgccaagcc cagagcttgc
     2521 gcaacgtgca gacgagagtc catacaggtc acaatagcta ctcttgtttt gggtttaagt
     2581 ggcagattta actgcccatg tagggcaaca taagcctgat tggcttgcat aaactgttca
     2641 aaatacgaca cgattccctc cttgaaaatt tgatagtcaa atatttctcc tatcttatca
     2701 tttttaagag aatttgtcac ggattatgca aagacctttt tcaagacttc ctgaatcgtt
     2761 gtcacgccaa tgacctgaat ttccttaggc agagtgattc ctgtcaagga attctgaggt
     2821 acataaatct tagtaaagcc cagtttagca gcttcgttga tgcgttgctc aatacgattc
     2881 acgcgccgaa tctctcctgt caagcccagt tctccgacaa aacattcctg aggattagtt
     2941 ggcttgtctt tgtagctcga agcaatagca actgcaacag ccaagtcaat ggcaggttca
     3001 tccaatttaa caccaccagc agatttgaga taggcatcct gattttgcaa gagaagccct
     3061 gcccgttttt ccaaaacagc cataatcaag ctagcacggt taaaatcaag tcctgtcgta
     3121 gtacgcttgg catttccaaa catggtcggt gttaccaaag cctgaacctc cgccaaaatc
     3181 ggacgcgtcc cttccatggt tacaacgatg gaggaaccag tcgccccatc caaacgctct
     3241 tctaggaaaa cttgactcgg attgagtacc tcaaccaagc cgcccgactg catctcaaaa
     3301 atcccaatct cattagtgga accaaaacga tttttgaccg ctctcaaaat acgaaaggtg
     3361 tggtgacgct ccccttcaaa gtaaagcacc gtatccacca tatgctccaa catacgaggc
     3421 ccagccaagg ttccttcttt ggtcacatga cctacgataa agatggcaat gttattggtc
     3481 ttggccaact gcatgagttc agcggtcact tcacgtacct gagaaacaga cccctgcacc
     3541 cctgaaatct caggagacat gatggtctgg atggaatcaa taatgagaaa gtctggctgg
     3601 atacgctcca cttctgcacg aacactctgc atattggtct ctgcatagag ataaaactca
     3661 ctatcaatat cacctaagcg ctctgcacgt agtttaatct gctgggcaga ctcctcccca
     3721 ctgacataga gaactgtccc cacttgggac aactgggttg agacttgtag gagaagagtt
     3781 gatttcccaa tcccaggatc cccaccgatg aggacgagac ttcctggtac cactccgcct
     3841 ccaagcacac ggttgaattc ctccatctcc gtcttggttc gattgatatt gatggaagtc
     3901 acctcagcta gtttcatggg cttggttttc tcacctgtca aggacacacg cgcattcttg
     3961 acctcggcaa cctcaacctc ttccacaaaa gaagaccaag acccacagtt ggggcaacgt
     4021 cccagatatt taggggaatt atacccacaa ttttgacata caaatgtcgc ttttttcttt
     4081 gcgatgacaa acctctttct atatctctaa ctcacactca atcacttggc aaaaatcaat
     4141 cttctcattt ggcacaaact ggcgcatgag cattcgatga gcaacaacta ccacagtctg
     4201 atgttctcga tacttagaca tacattctag aaaccgagac ttcatttccg tagctgtctc
     4261 atattgaata ggactattag gaagcaactc ccccttgttt tctaaaaaca gtcttctagc
     4321 tgtttcaaag ttttctattc ctgttttata gacctgccat tcatgtaata aaggctctac
     4381 tcttaaagga aaacccgtag cacagaccac atacgaagcc gtttctaaag ctcttgtgac
     4441 tgcagaagat acgattattt cagctgacga gagtaaagga tttttgctca atttctggac
     4501 ttgctgccgt cccatctcag acaagggtgc caaatctatc ccaaatccta tataagaacg
     4561 ctcctctaac tcacggtaat ctggctcccc atgacgtaca aagataatct tcattctagt
     4621 gccctgtcga tccaaatcca ccagttcgaa cgccatcagc cgcatctcca tctgcaatta
     4681 agaaagtagc aaaaacagcc tggacaatac gctccccaac ttcaagaaca acctcttggt
     4741 ctgtgatatt cttcatctgc gcaaaaatat gcccttcatt tccaggattt ccataataat
     4801 ccccatcaat gaccccaact gagttaatta aaaccaagcc cttcttacga ggatttgaag
     4861 aacgatcata gaggtagaga acctcagtcg gctgcatata agccttaacc cctgtcggaa
     4921 ccaagacaat ctctcctggc gcaacaactg tacgcacagc aacctttaag tcgtaaccag
     4981 ccgcatgcgc tgtctcacgc ttgggcaata aattttcatc tgtaaaactc gaaaccaatt
     5041 caaaaccacg aattttcata attttctctt ttctattatc atttattcta gattattcta
     5101 tcttatttat tcggaaaaag cacaaaaaaa gagcacacaa ttcaaatcgc ttagggctgc
     5161 tggattcctc ccctgacccg cttcacgcag aactgttgct ccactattta ttatatcaca
     5221 ttcctattca ttttaaaagc aaaattattt tttccgtcta tttctaaaaa aatcctgcat
     5281 gatagctgcg cattcatctt ccaaaattcc tatttcaacc tccacacgat gattgagacg
     5341 ctcatctgtc aagatattgt acaaactccc agcagcgcca aatttctggt ttttagcccc
     5401 atagaccaca tttggaatgc gggcaagccc aatcgctcca ctacacatga cacaaggttc
     5461 aatggtcaca aaaagtgtgc aatccagcaa gcgccagctc tcctcactca agttcgcatc
     5521 ctctatagcc ataatttccg catgcataac cgctcgctgt aattcctcac gcgcattatg
     5581 cccacgacca atgatttccc catctttgac aatcacacaa ccaattggaa tttcatcgtg
     5641 ttcaagagca atctcagcct ctctcaaagc ctccctcata aagacttctt tttcttcaag
     5701 cgtataatac atctcttttc tcttttccta cttatcgatt ttattattat atcatgaatc
     5761 ccaacacaaa aaaagccacc gaatgcggtg actctatagg gagattatta tgaaaaagaa
     5821 aagtttagga tatttgttac aacaagttag gaggtcttct tgtaactgtc tatagtatac
     5881 ccgacctatc ttaaacaaat cttaaaaatc tcttaggacc aaacactttc taaaatattt
     5941 gtttgttcac gaccaggacc tactgagaaa gtagaaatac gaacgccaac caattcactc
     6001 acacgacgaa catagttacg cgcattctca ggaagatctt ccaaattgcg aactccggta
     6061 atatcttctg accaacctgg caactcttca tagataggct tgcaacgttt caattgctca
     6121 agactagctg gatagtagtc aatacgttga ccgtcaagat cataggccac acagattttc
     6181 acagtatcca aaccgctcaa aacatcaata gagttcaaag aaaggttagt aataccagaa
     6241 acacgacggc tatgacgcat cacaactgag tcaaaccaac ctacacgacg tggacgacca
     6301 gttgttgtac catattcatg acccacttca cggatacgtt ctcccacttc atcaaacaac
     6361 tcagttggga aaggaccatc tcctacacga ctcgtataag ctttacatac acctacaacc
     6421 ttgtcaatct tgcttggacc gacaccagaa ccaattgtca caccaccagc tacagggttt
     6481 gatgacgtaa caaatggata agtaccttgg tcgatatcta gcataacacc ttgtgcacct
     6541 tcaaaaagca cacgtttgcc attatcaagc gcatcattca agataacaga tgtatctatc
     6601 acgtatttct tgatttgttg accatattcg taatattctt caaaaatatc atcgaaaaca
     6661 atcgctttac tgtcatacaa tttttcaaaa agacgattct tttcagcaag gttacgttct
     6721 aaacgctcac ggaaaatatc tttatctaaa agatctgcaa tacgaattcc aacacgagca
     6781 gccttgtcca tataagctgg accaattccc ttaattgtcg taccaatctt attgtcgccc
     6841 ttagcttctt cttgcaagcg atccaactcg atatgataag gcaaaataac atgcgcacga
     6901 tcagaaatac gcaagttatc agttgttaca ccttcctcat gaagatagct caactctttt
     6961 acaagagatt taggatttac aaccatacca ttcccaatga cagatatttt ttcagggaag
     7021 aaaatcccag atggaatcaa gtgcaactta aatttcttac cgtcaatcac aatcgtgtga
     7081 ccagcattat caccaccttg gtaacgtgca atcacttctg cattcgctga aaggaagtct
     7141 gtaatcttcc ctttaccttc atcaccccat tgggtaccta caacaacaac tgaagtcata
     7201 attttgtctg agccctcagg ctcttccttt ctcacataca tggcaggact ctcacctgca
     7261 attatatctt acaatttatt ataataaaaa atcgcctttt tatcaagaag aaacaataga
     7321 aagatttgct atttccaact attaaaaaat gatttagaaa aattac
//
LOCUS       DAVKZI010000069         7160 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKZI010000069 DAVKZI010000000
VERSION     DAVKZI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.070"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            63..572
                     /locus_tag="VXB18_002024"
     CDS             63..572
                     /locus_tag="VXB18_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383164.1"
                     /translation="MGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVK
                     NLNYSLITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFL
                     SLDDKEEIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEF
                     VKRVKEIEW"
     gene            complement(762..968)
                     /locus_tag="VXB18_002025"
     CDS             complement(762..968)
                     /locus_tag="VXB18_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0383165.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            1020..1496
                     /locus_tag="VXB18_002026"
     CDS             1020..1496
                     /locus_tag="VXB18_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0383166.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            1505..2176
                     /locus_tag="VXB18_002027"
     CDS             1505..2176
                     /locus_tag="VXB18_002027"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0383167.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            2307..2645
                     /locus_tag="VXB18_002028"
     CDS             2307..2645
                     /locus_tag="VXB18_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0383168.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            2648..3277
                     /locus_tag="VXB18_002029"
     CDS             2648..3277
                     /locus_tag="VXB18_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0383169.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            3517..4668
                     /locus_tag="VXB18_002030"
     CDS             3517..4668
                     /locus_tag="VXB18_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0383170.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            4981..5730
                     /gene="truA"
                     /locus_tag="VXB18_002031"
     CDS             4981..5730
                     /gene="truA"
                     /locus_tag="VXB18_002031"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0383171.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            5720..6493
                     /locus_tag="VXB18_002032"
     CDS             5720..6493
                     /locus_tag="VXB18_002032"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0383172.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKRGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            6471..6932
                     /locus_tag="VXB18_002033"
     CDS             6471..6932
                     /locus_tag="VXB18_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0383173.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKRKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         2110 a         1256 c         1582 g         2212 t
ORIGIN      
        1 ttaagccaac tttaaaagat agtttatcaa aaagatatgt cttcggaaga caaagaaggg
       61 gtttgggaca aatttattat ggtctaagta attttcctga tatagttatt ttagataaga
      121 cttatgaaaa caaatctagg aaaagtataa aaattgaaga atggaagaaa cttcgaggat
      181 gcgtggaagt taagaattta aattatagtt taattacaga ggaaaaaatc aaatcaacca
      241 tatcgaacag ttttgaacat ataactggag agatggaaca actaactgga gagatgggac
      301 aacttattgg agacctttta tggtataaaa aagtaattta tacaaatgga attgaatgga
      361 gatttctaag tttagatgac aaggaagaga tagataatac aattgttgaa gtagttaaca
      421 aaagaataga aacagaagaa gcgggaaatt cttttgattg gtggaagaat attaaagatt
      481 tatcgttcaa ttatacggat atatgcctat ctaaagattg tagacaagag tggaatgaat
      541 ttgtaaaaag ggtaaaggaa atagaatggt agaagtctat tctcattgag aaatttagat
      601 tttaagttac agtaagattt atttagagac taaaaaaaga ccactttatc ttatcaaaga
      661 aaaaagtgac cttcctgatt ttacagaaaa aataaagtga aaagactata attttacatg
      721 gaaatgtgct aaactagagg gagtggatta tcgccattga tttaggcttc ctggtttcca
      781 atcagggcgc gagttgggca atttttaaca gcctctaaga catcctgact aggagaaatt
      841 tctttttcca gttggtcagg gtcatcgtaa aaacgcacga ttccattatc gtggtaatca
      901 aataaatcag aataagtttg gcaaagtcca caggcgatac atcgttcagg tataagtgtg
      961 attttcatgt tcatatttat attgtaataa gaaaagtaaa aaaaaacaag gagtaaggta
     1021 tggcaaaaga accgtggcaa gaagatattt atgatcaaga agaatcaaga gcagggcgtc
     1081 ggcatcgaaa ccacggaggg gctgatagga tggctaatcg tattttgacg atcctagcta
     1141 gtattttctt tgtaattgtg gtggtgatgg tcatcgttct catctatcta tcatcggggg
     1201 ggagcaatcg cacagcagcc ttaaaagact ttcatgattc tgatgcaagt gtagtacaaa
     1261 tctcatcttc aagcagttct cagcctgagc agagttcaga gccagaatct acttctagta
     1321 gttcagaaga agctgctaat cctgaaggaa cgattaaagt tctcgcagga gaaggggaag
     1381 cagctattgc cgctcgtgca ggaatctcca ttgctcagtt agaggccttg aatcctgggc
     1441 acatggctac aggatcttgg tttgctaatc caggtgatgt tataaaaata aaataggagc
     1501 cgatatgaaa acaattcaaa ttgctattga tggtcctgct tccagcggta agagtacggt
     1561 cgcaaagatt attgctaagg attttggatt cacctacctt gatacaggag ctatgtatcg
     1621 tgcagcgacc tatatggctc ttaagaacca attaggagtt gaagaagtcg aagcccttct
     1681 agccttgttg gaccagcatc caatcagctt tggacgttca gaaactggag accagcttgt
     1741 ttttgtagga gatgtggata ttacccatcc tatccgtgaa aatgaagtga ccaatcatgt
     1801 ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg gtttctctcc aacaagaaat
     1861 tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt ggaactgttg tattgccaca
     1921 agcagaattg aaaattttcc tagtagcttc tgttgatgag agagcagagc gtcgttacaa
     1981 ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc ctaaaaaagg aaattgctgc
     2041 gcgtgactac aaggatagtc atcgtgagac ttctcctctc aaacaagcag aggatgctgt
     2101 ctaccttgat acaactggtt tgaacattca agaagtagtt gaaaaaatca aagcagaagc
     2161 tgaaaaaaga atgtaaatgt agaaaagccg atagattgat atcggttttt ttctaaattt
     2221 gtcaaaatgc tgattttagg gtataatagt tgctgttcga gaaattttga ttttcaaaga
     2281 atagtgaatg atgataagga gaaaccatga acaatttacc aaattgtcca aaatgtaact
     2341 cagagtatgt ctacgaagac ggtgccctac tggtttgccc agagtgtgct catgagtgga
     2401 atcctgctga agttgcagaa gtagaagaag gtcttgtcgc tatcgatgcc aacggaaata
     2461 aattgactga tggtgataca gtaactctca tcaaggactt gaaagtaaaa ggtgcgccaa
     2521 aagatttgaa acaagggacg cgcgtgaaaa atatccgcat cgtagaaggc gatcacaata
     2581 tcgactgtaa gattgatggt tttggtgcca tgaaacttaa atcagagttt gtgaggaaga
     2641 tttaagcatg tcaaaacact ataaacttgt attttatagc cgtatcttct tgtttctagc
     2701 ggcttttacg ggagtttatc ttgaaattac taggcatggt ggttttggga tgcttctcta
     2761 ttacacggtt ctgtccaacc tcttggtaac tatttttacc ctttatcttc taaaggttat
     2821 gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg cgcttaaaag gtggggtcac
     2881 catgagtatc atgattacct gtgtgattta ccatttcctc ttggcgccca ttgcgactaa
     2941 tttctatacc ctagaaaatt tcctttgcca ctatatcgtt cccatctggt ttttagcgga
     3001 taccctcttt tttgacaaac agggtcaata caagatttgg gatccagcag tgtggaccat
     3061 tttacccttt ctgtatatga tgtttgctct ttttaatggc ttggttctaa aactcaatat
     3121 tccaaatgcc aaggataatc ctttccctta cttctttttg aatgtgaaca agggttggaa
     3181 tgttgtgttt aagtggtgtc tgattatctt tgttgcctat atggtagcag gatttatttt
     3241 ctactttatc aagcaaatca agagaaagtc atcctaatac tcttcgaaaa tctcttcaaa
     3301 ccacgttagt ttccatctgc aacctcaaaa cactgttttg aacaacctgc ggctagcttt
     3361 ctagtttgct ctttgatttt cattgagtat gagatacaag ggattcattt tcgaatttaa
     3421 gaaggagtct acaaaccaat gaggcttctt cttttcttgc ttatttgata actatcaaaa
     3481 aagtagaaga ttaagagaaa tatagaaaga gatttcatga aacaattttt agaacgggcc
     3541 agcattttgg ctctctccct cgttttgatt acctcctttt ccatttcgag tgccctacca
     3601 gccatgtttg actattatca gggttattct aaggaacaaa ttgagctctt ggtgagcttg
     3661 ccttcctttg gaatcatgat gatgttactg ctaaatggtt tcttagaaaa aatatttcct
     3721 gagcgcttac agattagttt gggcttgctg attttatcat tgagcggtac agctcccttc
     3781 tggtaccaag cctatccctt tgtctttgga acacggcttc tctttggttt gggtcttggg
     3841 atgatcaatg ccaaggccat ttctattatc agtgaacgct accaaggaaa aaggcgaatt
     3901 cagatgttag ggctacgcgc ttctgcagag gtcgttggag cttctctcat taccttggcc
     3961 gtcggtcagt tgttggcctt tggttggaca gctatctttc tagcctatag tgctggattt
     4021 ttggtgctgc ccctttatct gctctttgtc ccttatggaa aatcaaagaa agaagtcaag
     4081 aaaagagcga aggaagcaag tcgtttaact cgagaaatga aaggcttaat ttttacctta
     4141 gctatcgaag cggcagttgt agtttgtacc aatacagcta ttaccatccg tattccaagt
     4201 ttgatggtgg aaagaggatt gggggatgcc cagttatcta gttttgttct tagtatcatg
     4261 cagttgatcg ggattgtggc tggggtgagt ttttctttct tgatttctat ctttaaagag
     4321 aaactgctcc tctggtctgg tattaccttt ggcttggggc aaatcgtgat tgccttgtct
     4381 tcatccttgt gggtggtagt agcaggaagt gttctggctg gatttgccta tagtgtagtc
     4441 ttgacgacgg tctttcaact tgtctctgaa cgaattccag ctaaactcct caatcaagca
     4501 acttcatttg ctgtattagg ctgtagtttc ggagccttta cgaccccatt tgttctaggt
     4561 gcaattggct tactaactca caatgggatg ttggtcttta gtatcttagg aggttggttg
     4621 attgtaatct ctatctttgt catgtaccta cttcagaaga gagcttagga ttgattccta
     4681 agtttttctt ttgatactca atgaaaatca aagagcatag ttgattgagt ttggaatagt
     4741 acgctgtagc tgctaaaata tttctagaaa ttaatttgac ttttctaata gagttattca
     4801 tatcttattt caatctacta tagaaagcta gccgcaggtt gctcaaaata gtgttttgag
     4861 gttgcagatg gaaactgacg tggtttgaag agattttcga agagtatgag atttttatac
     4921 ccatacaata tttgttttag gtccttgttt acagactaat ttcttgataa aatagaggtt
     4981 atgacgagat ataaagcaac tatttcctat gatggttatg cctttgctgg ctttcagcgc
     5041 cagtctcatg cgcgtagcgt tcaggaagaa attgaaaaaa ccttgaccag attaaataaa
     5101 gggcaaacca ttactgttca cggtgctggt aggacagata gtggggttca tgccctggga
     5161 caggtcattc attttgacct gccttatcag atggatgagg agaaactccg ttttgccttg
     5221 gatacccagt ctcctgaaga tattgatgtg atttcgattg agcttgtggc agatgatttt
     5281 cattgccgtt atgccaaaca tagcaagacc tatgagttta ttgtggatag aggacgtccc
     5341 aaaaatccga tgcgccgtca ctatgccacc cactttccct acccactcga tgtggaacga
     5401 atgcagattg caatcaaaaa gctagaggga acccatgatt ttaccggttt tacagcctct
     5461 gggactagtg tagaggataa ggttcgcacc atcacagaag ctagtttaat agtcgatgag
     5521 acaggacaat ttttgacctt taccttttca ggaaatggtt tcttgtataa acagattcgc
     5581 aatatggtgg ggactcttct caaaatcggt aacaaccgca tgccagtaga gcagattgat
     5641 ctcatcttgg agaagaagga caggcaactt gcaggtccca ctgcagcacc aaatggtttg
     5701 tatttaaagg agattcgtta tgaagaataa tcgtatttta gcactttctg gaaatgatat
     5761 ttttagtggt ggtggactgt cagctgattt ggctacctat accttgaacg gcttgcatgg
     5821 gtttgtagca gtgacttgtt tgacagcctt gacagaaaaa ggatttgaag tctttccaac
     5881 tgatgatacc atttttcaac atgaattaga tagcttgcgt gatgtggaat ttgggggaat
     5941 taagattggt cttctcccta ctgtcagtgt ggctgagaag gccttggact ttatcaaaca
     6001 acgcccagga gtacctgtgg tgttggatcc tgtcttggtc tgcaaggaaa cgcatgatgt
     6061 agctgtcagt gagctctgcc aagagttgat tcgctttttc ccttatgtca gtgtgattac
     6121 gcctaatctc ccagaagcag aattattatc cggtcaggaa attaaaacct tggaagacat
     6181 gaaaactgca gcgcagaaat tgcatgattt aggagcgcca gcagtcatta tcaagagagg
     6241 caatcgtctt agtcaggaca aggctgtgga tgtcttttat gatggacaga cctttactat
     6301 cctagaaaat ccagttatcc aaggccaaaa tgctggtgca ggttgtacct ttgcctctag
     6361 cattgccagt cacttgatta aaggtgataa acttttgcca gcagtagaaa gctctaaggc
     6421 tttcgtttat cgtgctattg cacaagcaga tcagtatgga gtaagacaat atgaagcaaa
     6481 caaaaacaac taaaatcgcc cttgtatccc tattaaccgc cctttctgta gttctaggtt
     6541 atttcttaaa aatcccaaca cctacaggaa ttctaactct tttagatgct ggtgtcttct
     6601 ttgcggcctt ttactttggt agtcgtgaag gagcggtagt cggaggacta gcaagtttct
     6661 tgattgacct cttatcaggc taccctcagt ggatgttctt tagcttggtc aaccatggct
     6721 tgcagggatt tttcgcagga tttaaaagaa aaagtcagtg gttaggcctt attttagcaa
     6781 ctattgccat ggtaggaggc tacgccttgg gttctacttt gatgaatggc tgggcagcag
     6841 ccctcccaga aattctacca aatttcatgc aaaatatggt agggatgatt gtaggattta
     6901 ttcttagtca aagtatcaag aagattaagt aatactcttc gaaaatctct tcaaaccacg
     6961 tcagctttca tctgcaacct caaaccactg ttttgagcag cctgaggcta gctttctagt
     7021 ttgcactttg attttcattg agtataaaga ggttgagtaa aaagtatttc aaataagaaa
     7081 aacgcatagt atcaggtgtt gaatgaactg ccccccaaaa gttagacaga aaaaatctaa
     7141 cttttggggt gttttattat
//
LOCUS       DAVKZI010000070         7121 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKZI010000070 DAVKZI010000000
VERSION     DAVKZI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.071"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(36..1028)
                     /locus_tag="VXB18_002034"
     CDS             complement(36..1028)
                     /locus_tag="VXB18_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0383174.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1188..2942
                     /locus_tag="VXB18_002035"
     CDS             1188..2942
                     /locus_tag="VXB18_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383175.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            2926..4647
                     /locus_tag="VXB18_002036"
     CDS             2926..4647
                     /locus_tag="VXB18_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383176.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            4658..5287
                     /locus_tag="VXB18_002037"
     CDS             4658..5287
                     /locus_tag="VXB18_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0383177.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGSYCVGYFTPCLILWCYLN"
     gene            5188..5745
                     /locus_tag="VXB18_002038"
     CDS             5188..5745
                     /locus_tag="VXB18_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0383178.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFIAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGISFKNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            5733..7097
                     /locus_tag="VXB18_002039"
     CDS             5733..7097
                     /locus_tag="VXB18_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383179.1"
                     /translation="MVEIKNLSLDYGEERILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLCLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2567 a          941 c         1268 g         2345 t
ORIGIN      
        1 aattcatata aaaacatggc ttgtaaaaaa ttactttaat cacaataatc gcatttaaaa
       61 ttgtgatgtt tgcaagctaa attacggact tcacttggaa gttttccctt gtatctttta
      121 taatagatag aaaatttgct ggcagatgaa tatccaacag attctgctat ctcttttata
      181 ggtagttcag tgtttaaaag aagagtttca gctacattca ttctttttct ttgagtgtac
      241 tctgtaatgc tttgacaata tttttcctta aataaatttt ttaatttagt accactcatt
      301 ttagatattt tttcaagcgt gccttgattt acattcgttg caaaatgatc atctaagaat
      361 cttgctacat cttcaagtgc tttatcatca tcaatttcaa ttttatattt ttttctattt
      421 aagtatgtgt caattactat acttatccat tcatttgcct ttgctttaaa gaaaaaatca
      481 gcggcaggag cgtccatctt acaatttaat atttccattg ccactctttc taaggccttt
      541 gtaagtatta tttgattcgg ttgaagcaag gttgaataaa aagattctgg attaatgtta
      601 atagatgcta aatgtttttc tattagctct tttttaaaac caatggaaac agcaagataa
      661 caacaattct cgtgtaataa aaaaacaaaa tcatctttta tattatcaaa atcaaaagta
      721 cataaagagt ttgcggtaat agtttgatac ggattaaact tttctccgtt tgcactgaca
      781 atgtaacttg aataaattga aacatagtct gacatactat aagtgctatt ttgaactact
      841 tcctctttga tataaaaatc atgtatatcg ataatgaagc tgcctccttc ataaaaccaa
      901 tataggcctt ctgcataagt tgaattctct tttttccaac aaaatgtatg acctgcactt
      961 gaatacttct cattgttttt acattcatct actttcatat aatcttttac aaaatcataa
     1021 tatgacataa cacactatcc cttttagaca atattccaat tagccttatt aattcaaaac
     1081 tattgtatta gtaattataa cagatgtata atagaaaagc aatgatagat attatcaatt
     1141 aagcgaattt atatctaaaa gggatattaa agaaaggaga tatgcttatg aagatttaca
     1201 aaaaactatt tgcttatgtc caagataaga aatatcttgg ggttttggcc ataatttttt
     1261 ctgctatatc tgctctactt acagtatatg gatattattt aatctacaaa tttctagata
     1321 agttaataat taattcaaat ttatccggtg cagagagcat agcattaaaa tctgttatta
     1381 cactaacaag tggagcgata ttttattttg tctcaggaat gttttcacat atcttgggat
     1441 tcaggcttga aacaaattta agaaaaaggg gaatcgatgg tctggaaaaa gcaagtttta
     1501 ggttctttga cttaaatcca tctggtcaaa taagaaagat tatagatgac aatgctgcac
     1561 aaactcatca ggtggtagca cacatgattc ccgatagttc tcaggcaata atcacacccg
     1621 tacttgtact tgcacttggc tttatagtaa gtataagagt tggcataatt ttgcttgctc
     1681 ttactataat tggtggctta attttagggg cgatgatggg cgagcaagaa tttatgaaga
     1741 tataccaaga atccctatct aaactaagtg ctgaaactgt tgagtacgtg agaggaatgc
     1801 aagttgtaaa aatatttaaa gcaaatgtag agtcatttaa aagcttttac aaggctataa
     1861 aagattactc aaagtatgct tatgattatt ccctatcttg taaaaggcct tatgttttgt
     1921 atcaatggtt attttttgga ctgattgcaa ttttaattat tcctatagtt tattttatga
     1981 ctagcttagc tagcgcaaag gtgattttac ttgagcttat catgatttta tttttatcag
     2041 gagttctctt tgtttcattc atgagaatga tgtggtactc catgtatatt tctcaaggaa
     2101 attatgcagt agatacttta gaggcgcttt acgaagatat gcaaaaagac aaattagtgc
     2161 atggtaatgt caataatttt aaaaactata atatagaatt tgagaatgtt agctttgctt
     2221 ataatgataa agctgtcatt gaaaatttat cctttaattt agaagaagga aagtcctacg
     2281 cacttgtcgg ttcatctgga tcaggcaaat caacagtagc aaaacttata tcaggttttt
     2341 acaatgttaa taaaggaagc ataaagatag gcgggatagc aataagtgaa tattctgacg
     2401 aagccttaat taaagccatt tcctttgttt ttcaagattc aaaattattc aagaagagca
     2461 tttatgataa tgtagcttta gctaataaag atgcgacgaa agatgacgtt atgagagcct
     2521 taaaattagc aggatgcgat ttaatattag acaaattccc agaaagagaa aatacaatca
     2581 taggctcaaa aggtgtttat ttatccggtg gagaaaaaca aagaattgca attgctagag
     2641 caattttaaa ggattccaaa attattatta tggatgaagc atcagcatct attgacccag
     2701 ataacgagtt tgaattgcaa aaagctttca aaaatcttat gaaggataaa acagttatca
     2761 tgattgcaca caggctatct acaattaaag accttgatga aattattgtt atggatagtg
     2821 gaaaaattat agaaagaggg tctgacaaag aattaatgtc aaaagataca aggtataaga
     2881 gcctgcaaga gatgtttaac agtgcgaatg aatggagggt ttcaaatgaa agagttttat
     2941 aaaaaaagat ttgctcttac agatggagga gcaagaaatt taagtaaagc aacactggct
     3001 tcatttttcg tttattgtat aaacatgctt cctgccatat tacttatgat ttttgctcag
     3061 gaagttttgg aaaatatggg caaaagcaat ggcttttata tagtattctc agttttgact
     3121 ttgatagcaa tgtatatttt gctttctatc gaatacgata aattatataa cacaacctat
     3181 caagaaagtg cagatttaag aataaggaca gcggagaatt tatcaaaatt acctctatct
     3241 tacttttcta aacatgacat ttccgacatt tcacaaacaa tcatggctga tattgaaggc
     3301 atagagcatg caatgagcca ctcaatacca aaggtgggcg gcatggtact gtttttccca
     3361 ttaatatctg taatgatgct agcgggcaat gtcaagatgg gtttagctgt aattatccca
     3421 tctattttaa gctttatatt tataccttta tctaaaaaat atcaggttaa tggacagaat
     3481 agatattatg atgtcttaag aaaaaactca gaaagctttc aagaaaatat cgaaatgcaa
     3541 atggagatta aagcatataa tttatcgaag gatattaaag atgacttata taaaaaaatg
     3601 gaagatagtg agagagtaca cttaaaggcg gaagtaacta caattttaac tttgtctata
     3661 tcttcaatat ttagctttat atctcttgct gttgtgatat ttgtcggcgt aaatctaatt
     3721 attaataaag agataaattc tctctacctt ataggatatt tactagctgc tatgaagata
     3781 aaagactctt tagatgcatc taaagagggc ttgatggaaa tattttattt atcgcccaaa
     3841 atagaaagat taaaagaaat tcaaaatcaa gatttacaag aaggcgatga ctatagctta
     3901 aaaaaatttg atattgatct aaaagatgtt gagtttgcct acaataaaga cgcaaaagtt
     3961 ttaaatggtg taagttttaa agctaagcag ggagaggtca ctgctttggt aggtgcaagt
     4021 ggctgcggta aaacaactat cttgaaactt atatcaagac tttatgatta tgacaaggga
     4081 caaatcttaa tcgatggcaa agatataaaa gaaatatcaa cagaatctct ttttgataag
     4141 gtctctatag ttttccaaga tgtggttctc tttaatcaaa gcgttatgga aaatattaga
     4201 atcggaaagc aagatgcaag tgacgaagag gttaaaagag cagcaaaact tgcaaattgc
     4261 acagatttta tagaaaaaat ggataaaggt ttcgatacag ttattggtga gaacggagct
     4321 gagctatcag gaggagaaag acaaagatta tcaatagcca gagccttctt aaaagatgcg
     4381 ccgatattga tcttagatga gataacagca agccttgatg ttaacaacga gaaaaagatt
     4441 caagagtctt taaataattt agttaaagat aaaactgttg taatcatttc acatagaatg
     4501 aaatccatag aaaatgcaga caagatagta gttcttcaaa acggaagagt agaaagcgaa
     4561 ggtaagcatg aagagctttt acaaaaatca aaaatttaca aaaatttaat agaaaagaca
     4621 aaaatggcag aagaatttat ttattaggag gactacaatg gataataaaa aattaaaagt
     4681 aaaagattta gtaagcatcg gtgtttttgg cgtaatttat tttgccttca tgtttggagt
     4741 tggtatgatg ggcttgattc caatattgtt cttaatatac ccgacagtat tagccatagt
     4801 tgcaggaact gttgttatgt tatttatggc taaggttcaa aagccatggg cactatttat
     4861 atttggtatg atatcaccac ttgtgatgtt tgcagctggt catacctacg tagttgtggt
     4921 tttatcactt atagtaatga taatagcaga attaattaga aagattggta attataattc
     4981 atttaaatac aatatgcttt cttatgcaat cttcagcaca tggatatgta gctctttaat
     5041 gcaaatgctt ttagcaaaag aaaaatatat ggagtggtct ttgatgacga tgggaaaaga
     5101 ttatgttgat gtgttagaaa agttaataac ttatcctcat atggctttag tagccttagg
     5161 tgctttctta ggaggaattc ttggagcata tataggcaag gctctattga aaaaacactt
     5221 ttcaaatgga tcatattgtg tgggatactt tactccttgc ctaattttat ggtgttatct
     5281 gaattaaacc ctatagttaa gatgtttttg agtataccta ttgttattag aatgtttatt
     5341 ttaccattta tagcagcaag ctttatgata aagacctcgg atgtaggcgc aataatttca
     5401 tcgatggata agcttaagat ttcaaagaat gtatccatac ctattgcggt tatgtttaga
     5461 ttcttcccat cttttaagga ggagaagaaa aacatcaaaa tggctatgag agtaagaggg
     5521 ataagtttta aaaacccagt caaatatctt gaatatgttt ctatgccact actcattata
     5581 tcatctaata tatcagatga cattgcaaaa gcggcagaaa caaaggcaat agaaaatcca
     5641 attgccaaga ccagatacat tcgcgtaaag atacagctaa ttgattttgt ttatgtttta
     5701 gcggttgctg gacttattgt gggaggctta atatggttga aataaaaaat ttaagtcttg
     5761 attatggtga agagcgtata ttagatgata tatcactatc catagccgag ggagagtgcg
     5821 tgctatttac aggaaaaagt ggaaatggta agtcatcttt aataaattca ataaatggac
     5881 tagctgtaag gtatgataac gcaaagacaa agggcgaaat aattattgat ggtaagaata
     5941 taaaaaattt ggaactttat caaatctcaa tgcttgtttc aactgttttt caaaatccta
     6001 agacctattt ttttaatgtc aatacgacat tagaattatt attttatttg gaaaatatcg
     6061 gtcttgcaag agaagagatg gacaggcgtt tgaaggatat gcttaagata ttcccgataa
     6121 aaaatctttt gaacagaaat atatttaatc tatccggcgg tgaaaaacaa attctttgca
     6181 ttgcagcttc ttatatagca ggtacaaaga ttatagttat ggatgagcct tcatcgaatt
     6241 tagatattaa aagcataagt gttttggcaa agatgctaaa gatattaaaa gagaaaggta
     6301 taagcataat tgttgcagag catagaattt attatttgat ggacatagtt gaccgtgtat
     6361 ttttaataga taaaggaaag cttaaaaaaa cttatactag aagtgaattt ttaaagctag
     6421 ataaaaatga attaaatgct ttaagtttaa gagataaaga attaagtaaa ttaaaagttc
     6481 cttatttaaa agaaggtgga gagtatcaga taaaaaatct tagctacaaa tttactgatg
     6541 atgagtgttt aagcttaaaa gatatttcat tcaagcttgg gaaaatttat ggcataatag
     6601 gatccaacgg acgaggaaaa tcaacgcttt taagatgttt aataggtctt gagaaaaaat
     6661 caaaagaaga aatttatttt aagggagaga agctatctaa aaaagaaaga ctcaaaaact
     6721 cttcacttgt tatgcaagat gtaaatcatc aattattcac agatgaagta ttcaacgagc
     6781 ttagattagg agtaaagaat tttgatgaag aaaaggcgaa aatcatttta aaagatttat
     6841 gcctggacga atttattgaa aggcatccga tgagtttatc aggagggcaa aagcaaaggc
     6901 ttgcaatagc atctgttatg tgcaagaatt ctccatttgt cttttttgac gaaccttcaa
     6961 gtggtatgga ttattccaat atgataaaaa tatctgaact gattaataag tataaaacca
     7021 tggataaaat aatttttatt gtttcccatg atatagaatt tttaaatgaa gtggcagatg
     7081 aaatttttga attgtaaaat agagtctgtt aaacatgtct a
//
LOCUS       DAVKZI010000071         7003 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKZI010000071 DAVKZI010000000
VERSION     DAVKZI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.072"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            52..6468
                     /locus_tag="VXB18_002040"
     CDS             52..6468
                     /locus_tag="VXB18_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0383180.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPHEVVLADTSNSEDALSISDKEKV
                     AENKEKHENIHSAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKEDSNQS
                     QGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTYDRIFN
                     GSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFI
                     RGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDASSNFTKIHRIKFADQADEKGMISYY
                     LVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGEASLEI
                     NKTISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAYDDGSA
                     LQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIKATKY
                     DSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAVDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
BASE COUNT         2750 a          963 c         1357 g         1933 t
ORIGIN      
        1 agttaaagtt tattatctat tggagtttaa ataaatatgt aaggaattaa aatgaaaaaa
       61 agtacagtat tgtcattaac cacagctgca gttattttag cagcctatgc ccctcatgag
      121 gtagtcttag cagacacatc taactctgaa gatgctttaa gcatctctga taaagaaaaa
      181 gtagcagaaa ataaagagaa acatgaaaat atccatagtg ctatagaaac ttcacaggat
      241 tttaaagaga agaaaacagc agtcattgag ggaaaagaag ttgttagtaa aaatcctgtg
      301 acagacaata acactagcaa tgaagaagca agaatcaaag aagattccaa tcaatcccaa
      361 ggagatcata cggactcatt tgtgaataaa aacacagaaa atcccaaaaa agaagataaa
      421 gttgtctata ttgctgaatt taaagataaa gaatctggag aaaaagcaat caagcaacta
      481 tccaatctta agaatacaaa agttttatat acttatgata gaatttttaa cggtagtgcc
      541 atagaaacaa ctccagataa cttggacaaa attaaacaaa tagaaggtat tacatcggtt
      601 gaaagggcac aaaaagtcca acccatgatg aatcatgcca gaaaggaaat tggagttgag
      661 gaagctattg attacctaaa gtctatcaat gctccgtttg ggaaaaattt tgatggtaga
      721 ggtatggtca tttcaaatat cgatactgga acagattata gacataaggc tatgagaatc
      781 gatgatgatg ccaaagcctc aatgagattt aaaaaagaag acttaaaagg aactgataaa
      841 aattattggt tgagtgataa aatccctcat gcgttcaatt attataatgg tggcaaaatc
      901 actgtagaaa aatatgatga tggaagggat tattttgacc cacatgggat gcatattgca
      961 gggattcttg ctggaaatga tactgaacaa gatatcaaaa actttaacgg catagatgga
     1021 attgcaccta atgcacaaat tttctcttac aaaatgtatt ctgacgcagg atctgggttt
     1081 gcgggtgatg aaacaatgtt tcatgctatt gaagattcta tcaaacacaa cgttgatgtt
     1141 gtttcggtat catctggttt tacaggaaca ggtcttgtag gtgagaaata ttggcaagct
     1201 attcgggcat taagaaaagc aggcattcca atggttgtcg ctacgggtaa ctatgcgact
     1261 tctgcttcaa gttcttcatg ggatttagta gcaaataatc atctgaaaat gaccgacact
     1321 ggaaatgtaa cacgaactgc agcacatgag gatgcgatag cggtcgcttc tgctaaaaat
     1381 caaacagttg agtttgataa agttaacata ggtggagaaa gttttaaata cagaaatata
     1441 ggggcctttt tcgataagaa taaaatcaca acaaatgaag atggaacaaa agctcctagt
     1501 aaattaaaat ttgtatatat aggcaagggg caagaccaag atttgatagg tttggatctt
     1561 aggggcaaaa ttgcagtaat ggatagaatt tatacaaagg atttaaaaaa tgcttttaaa
     1621 aaagctatgg ataagggtgc acgcgccatt atggttgtaa atactgtaaa ttactacaat
     1681 agagataatt ggacagagct tccagctatg ggatatgaag cggatgaagg tactaaaagt
     1741 caagtgtttt caatttcagg agatgatggt gtaaagctat ggaacatgat taatcctaat
     1801 aaaaaaactg aagtcaaaag aaataataaa gaagatttta aagataaatt ggagcaatac
     1861 tatccaattg atatggaaag ttttaattcc aacaaaccga atgtaggtga cgaaaaagag
     1921 attgacttta agtttgcacc tgacacagac aaagaactct ataaagaaga tatcatcgtt
     1981 ccagcaggat ctacatcttg ggggccaaga atagatttac ttttaaaacc cgatgtttca
     2041 gcacctggta aaaatattaa atccacgctt aatgttatta atggcaaatc aacttatggc
     2101 tatatgtcag gaactagtat ggcgactcca atcgtggcag cttctactgt tttgattaga
     2161 ccgaaattaa aggaaatgct tgaaagacct gtattgaaaa atcttaaggg agatgacaaa
     2221 atagatctta caagtcttac aaaaattgcc ctacaaaata ctgcgcgacc tatgatggat
     2281 gcaacttctt ggaaagaaaa aagtcaatac tttgcatcac ctagacaaca gggagcaggc
     2341 ctaattaatg tggccaatgc tttgagaaat gaagttgtag caactttcaa aaacacggat
     2401 tctaaaggtt tggtaaactc atatggttcc atttctctta aagaaataaa aggtgataaa
     2461 aaatacttta caatcaagct tcacaataca tcaaacagac ctttgacttt taaagtttca
     2521 gcatcagcga taactacaga ttctctaact gacagattaa aacttgatga aacatataaa
     2581 gatgaaaaat ctccagatgg taagcaaatt gttccagaaa ttcacccaga aaaagtcaaa
     2641 ggagcaaata tcacatttga gcatgatact ttcactatag gcgcaaattc tagctttgat
     2701 ttgaatgcgg ttataaatgt tggagaggcc aaaaacaaaa ataaatttgt agaatcattt
     2761 attcattttg agtcagtgga agaaatggaa gctctaaact ccaacgggaa gaaaataaac
     2821 ttccaacctt ctttgtcgat gcctctaatg ggatttgctg ggaattggaa ccacgaacca
     2881 atccttgata aatgggcttg ggaagaaggg tcaagatcaa aaacactggg aggttatgat
     2941 gatgatggta aaccgaaaat tccaggaacc ttaaataagg gaattggtgg agaacatggt
     3001 atagataaat ttaatccagc aggagttata caaaatagaa aagataaaaa tacaacatcc
     3061 ctggatcaaa atccagaatt atttgctttc aataaccaag ggatcaacgc tccatcatca
     3121 agtggttcta agattgctaa catttatcct ttagattcaa atggaaatcc tcaagatgct
     3181 caacttgaaa gaggattaac accttctcca cttgtattaa gaagtgcaga agaaggattg
     3241 atttcaatag taaatacaaa taaagaggga gaaaatcaaa gagacttaaa agtcatttcg
     3301 agagaacact ttattagagg aattttaaat tctaaaagca atgatgcaaa gggaatcaaa
     3361 tcatctaaac taaaagtttg gggtgacttg aagtgggatg gactcatcta taatcctaga
     3421 ggtagagaag aaaatgcacc agaaagtaag gataatcaag atcctgctac taagataaga
     3481 ggtcaatttg aaccgattgc ggaaggtcaa tatttctata aatttaaata tagattaact
     3541 aaagattacc catggcaggt ttcctatatt cctgtaaaaa ttgataacac cgcccctaag
     3601 attgtttcgg ttgatttttc aaatcctgaa aaaattaagt tgattacaaa ggatacttat
     3661 cataaggtaa aagatcagta taagaatgaa acgctatttg cgagagatca aaaagaacat
     3721 cctgaaaaat ttgacgagat tgcgaacgaa gtttggtatg ctggcgccgc tcttgttaat
     3781 gaagatggag aggttgaaaa aaatcttgaa gtaacttacg caggtgaggg tcaaggaaga
     3841 aatagaaaac ttgacaaaga cggaaatacc atttatgaaa ttaaaggtgc aggagattta
     3901 agaggaaaaa tcattgaagt cattgcatta gatgcttcta gcaatttcac aaagattcat
     3961 agaattaaat ttgctgatca ggctgatgaa aaggggatga tttcttatta cctagtagat
     4021 cctgacaaag atgcttctaa atatgaaaaa cttggtgaaa tttctgaaga taaactcaaa
     4081 aatgcaaaga gcccagagga aaataccaat aataatcaag ctaaggatga agattcaaaa
     4141 ccagatgaaa aaagttcagt tgagggagaa gctagccttg aaataaataa aactatttca
     4201 acaattagag actttgaaaa taaagaccta aagaaactca ttaaaaagaa atttagagaa
     4261 gttgatgatt ttacaagtga aactggtaag agaatagagg aatacgatta taaatacgat
     4321 gataagggaa atattattgc ttatgacgat ggtagtgcct tacaatatga aactgaaaaa
     4381 tttgacgaaa taaaatcaaa aatttatggt gttctaagcc catctaaaga tggacacttt
     4441 gaaattcttg gaaagataag caatgtttct aaaaatgcca aggtatatta tggaaatagc
     4501 tataaatcga tagaaatcaa agcgactaag tatgattcac attcaaaaac gatgatattt
     4561 gatttatacg ctaatattaa tgatattgta gatggattag cttttgctgg agatatgaga
     4621 ttatttgtta aagatgacaa tcaaataaaa gctgaaacta aaattagaat gcctgaaaaa
     4681 aataaggaaa ctaaagcaga atatccctat gtatcaagtt atgggaatgt aatcgaatta
     4741 ggagaaggag atctttcaaa gaacaaacca gacaatttaa ctaaaatgga atctggtaaa
     4801 atctattctg attcagaaaa acaacaatat ctgttaaagg ataacatcat tctaagaaaa
     4861 ggctatgcac taaaagtgac tacctataat cctggaaaaa cggatatgtt agaaggaaat
     4921 ggagtctata gcaaggaaga tatagcaaaa atacaaaagg ccaatcctaa tctaagagtc
     4981 ctttcagaaa caacaattta tgctgatagt agaaatgttg aagatggaag aagtacccaa
     5041 gctgtattaa tgtcggcttt ggacggcttt aacattataa ggtatcaagt gtttacattt
     5101 aaaatgaacg ataaagggga agctgtcgat aaagacggaa atcttgtgac agattcttct
     5161 aaacttgtat tatttggtaa ggatgataaa gaatacactg gagaggataa gtccaatgta
     5221 gaagctataa aagaagatgg ctccatgtta tttattgata ccaaaccagt aaacctttca
     5281 atggataaga actactttaa tccatctaaa tctaataaaa tttatgtacg aaatccagaa
     5341 ttttatttaa gaggtaagat ttctgataag ggtggtttta actgggaatt gagagttaat
     5401 gaatcggttg tagataatta tttaatctac ggagatttac acattgataa cactagagat
     5461 tttaatatta agctgaatgt taaagacggt gacatcatgg actggggaat gaaagactat
     5521 aaagcaaacg gatttccaga taaggtaaca gatatggatg gaaatgttta tcttcaaact
     5581 ggctatagcg atttgaatgc taaagcagtt ggagtccact atcagttttt atatgataat
     5641 gttaaacccg aagtaaacat tgatcctaag ggaaatacta gtatcgaata tgctgatgga
     5701 aaatctgtag tctttaacat caatgataaa agaaataatg gattcgatgg tgagattcaa
     5761 gaacaacata tttatgtaaa tggaaaagaa tatacatcat ttgatgatat taaacaaata
     5821 acagacaaga cactaaacat taagattgtt gtaaaagatt ttgcaagaaa tacaaccgta
     5881 aaagaattca ttttaaataa agatacggga gaggtaagtg aattaaaacc tcatagggta
     5941 actgtgacca ttcaaaatgg aaaagaaatg agttcaacga tagtgtcgga agaagatttt
     6001 attttacctg tttataaggg tgaattagaa aaaggatacc aatttgatgg ttgggaaatt
     6061 tctggtttcg aaggtaaaaa agacgctggc tatgttatta atctatcaaa agataccttt
     6121 ataaaacctg tattcaagaa aatagaggag aaaaaggagg aagaaaataa acctactttt
     6181 gatgtatcga aaaagaaaga taacccacaa gtaaaccata gtcaattaaa tgaaagtcac
     6241 agaaaagagg atttacaaag agaagatcat tcacaaaaat ctgattcaac taaggatgtt
     6301 acagctacag ttcttgataa aaacaatatc agtagtaaat caactactaa caatcctaat
     6361 aagttgccaa aaactggaac agcaagcgga gcccagacac tattagctgc cggaataatg
     6421 tttatagtag gaatttttct tggattgaag aaaaaaaatc aagattaaga caaaagctat
     6481 agaaaaaaat ggtttatgta ctgagattag atagtgaggt gatgacatag ttttgtgaaa
     6541 acggccattt ataactcaat tatttagttt acttcacttc actattgata ctatttggag
     6601 ttattaatgg acttagttta gataactaat gaattgattg aaagggttag tattgacaat
     6661 attggtcata ttgattagaa aatagagtct atcaaaattt aaaggctaat agaggtgatg
     6721 agacaatttc aaggaattaa gtagcgtttg gttgcttaat tcctttttat ttggaaggaa
     6781 gtttttcgta accgcccaat aacgaagtct attggacggt tacgatatga tcactgactt
     6841 cgtcagtctt atctacaacc tcaaaactgt gttttgagca acctgcggct agcttcctag
     6901 tttactcttt gattttcatt gagtattaga acagaaaaaa tgcttggagt atttgtttgt
     6961 gtgtttattt ttatataaca aactataaac aaaacaaaaa tat
//
LOCUS       DAVKZI010000072         6925 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKZI010000072 DAVKZI010000000
VERSION     DAVKZI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.073"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(125..400)
                     /locus_tag="VXB18_002041"
     CDS             complement(125..400)
                     /locus_tag="VXB18_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0383181.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(507..1346)
                     /locus_tag="VXB18_002042"
     CDS             complement(507..1346)
                     /locus_tag="VXB18_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0383182.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1488..2336
                     /locus_tag="VXB18_002043"
     CDS             1488..2336
                     /locus_tag="VXB18_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0383183.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2429..3346)
                     /locus_tag="VXB18_002044"
     CDS             complement(2429..3346)
                     /locus_tag="VXB18_002044"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0383184.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3784..3989
                     /locus_tag="VXB18_002045"
                     /pseudo
     CDS             3784..3989
                     /locus_tag="VXB18_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4300..4593)
                     /gene="rpmA"
                     /locus_tag="VXB18_002046"
     CDS             complement(4300..4593)
                     /gene="rpmA"
                     /locus_tag="VXB18_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0383185.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4610..4954)
                     /locus_tag="VXB18_002047"
     CDS             complement(4610..4954)
                     /locus_tag="VXB18_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0383186.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4970..5284)
                     /gene="rplU"
                     /locus_tag="VXB18_002048"
     CDS             complement(4970..5284)
                     /gene="rplU"
                     /locus_tag="VXB18_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0383187.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5320..5407)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5502..6101)
                     /locus_tag="VXB18_002049"
     CDS             complement(5502..6101)
                     /locus_tag="VXB18_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0383188.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6568..6867
                     /locus_tag="VXB18_002050"
     CDS             6568..6867
                     /locus_tag="VXB18_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0383189.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2180 a         1400 c         1147 g         2198 t
ORIGIN      
        1 ctactatata tacaatattt tcggagcatt caacttttta actctattta ttactagatt
       61 tcataattaa aaagcctact gaccaagcta gaaagcttga tacaataggc tttttaaagg
      121 ctgattattt aacagcgtct ttaagagctt taccagcttt gaatgctgga actttagaag
      181 ctgcaattgt catttcttta ccagtttgtg ggttgcgacc tttacgttct gcacgctcac
      241 gaacttcaaa gttaccaaaa ccgatcaatt gaactttttc accagctgca agatagtcag
      301 ctactgctgc aaatacagct tcaactgctg ctgctgagtc tttcttagtc aattctgtag
      361 cttctgctac tttagcgatc aaatcttgtt tgtttgccat gttaacgatt cctccaaata
      421 atttctaatt aacaaatata atcatatcct aaaatccctt ttaggtcaag ttaaaaacgc
      481 tatttcttcc cattttattt atttttttag gagtggtaac gtatcaaaat agcccaagcg
      541 ttctcacccg tgtgagtttg aataatggaa cccgtttcca aaacagaaat tggcttttca
      601 acataagctt gtaagctttc tttcatctct tttgcccaat catcactacc agaatatgaa
      661 attccaatct ctgctacagc acgttcagaa agcgatgtta tcaactcatc taaccatttt
      721 ttaaatgttt tagttccacg acctttaacc attggctgca attcatggtc tttcatttgc
      781 atgacaacac ggatattgag aagagagctc aacaagccag ttacacggct aattcgtcca
      841 cctttgacaa gattttccaa agttgaaaca ccaatataaa gctctgtatg gtttttaacc
      901 tcttctacat gacataaaat tgcctccata tctttacctt cttgagctaa cttcgcagcc
      961 tcaacaactt ggaatttcag ggcttggtca gtgaaggaac tatcaacaac agtcacatct
     1021 gcagtagata ggctagcacc ttggcgtgct gcttctaccg tacccgaaag agcatgggac
     1081 atatgaatag caagaatctg gccaccatct ttgcataggt cttcaaaaat ctcagcaaag
     1141 acacctacag gtggctgact tgttttcgga agattcttac tttcttgcat caactgaaga
     1201 aatttacctt cttctttcaa atccgcatca gaataaacaa cattatcaat cattacagat
     1261 aatggaacaa ttgtaatatc taattgcttt actagttcag gttcaatagt aacagatgaa
     1321 tcggttacaa tcttaatttt tgtcatagta tcaatctttc tattttagga ttcagattgg
     1381 tttccttact tctaattata tcaaaaaaaa gattaaaaat cctaatggag tcaatcaaat
     1441 tttccgtaaa atttgatata atcaacttat aagaaaagag gtgtcctatg attaaaaaaa
     1501 tttaccccat ttttaccatt ttactaggtg ctgctattta tgcttttgga ctgacttatt
     1561 ttgtagttcc ccatcatctc tttgaaggag gggcgacagg tattaccctc atcacatttt
     1621 atctttttaa aatccctgtt tccctcatga acctgctgat taatattccc cttttcatcc
     1681 tagcttggaa gatctttgga gccaaatccc tctattctag tttactagga accttagctt
     1741 tgtccggctg gttagctttt tttgagcata ttccccttca tattgatctt caaggtgatt
     1801 tactaatcac agcccttata gcgggaatcc tattgggaat tggccttgga attattttta
     1861 atgctggagg tacaactggc ggaactgata ttctagctcg tattctcaac aaatacactc
     1921 atatatccat aggaaaactg ctctttatct tagatttttg tattctcatg ttgattctcc
     1981 taatcttcaa ggatttgaga ttggtttcct acacgctttt gtttgatttt attgtttctc
     2041 gtgttattga tttgattggt gaaggaggat atgccggcaa aggctttatg attatcacaa
     2101 aacgtcctga ccaacttgct aaggcgatta atgatgacct cggaagaggt gttactttta
     2161 tttctggtca aggctactat agtaaagaaa atttgaaaat catttactgt attgtcggaa
     2221 gaaatgaaat tgtgaaaacg aaggaaatga ttcatcgaat cgatcctcaa gcctttataa
     2281 ctattacaga agcccatgaa atcctaggag aaggcttcac ctttgaaaaa gaataaaaag
     2341 aggtagtgtc gtgacctcaa aagttagact aaatcatcta tcttttgggt tacagacaac
     2401 ctcttttttg ttttatttac tcaagctctt aagaccaatt ccgagttact tcttcatcag
     2461 cctttaactg atccactaat tggtcaactg agtcaaattt ggtcatatct cgaatgcgat
     2521 caagccaata aaccatgacg gtttccccat aaatatcttg attaaaatca aaaatattga
     2581 cttcaaaacg tgcttcttct ccatcaaagg tcacattttt cccgacacta gccatagcac
     2641 gatacttctg tctttgaatc tcaacatcaa cgacataaac gccatctgct ggcatataag
     2701 tacggtctaa aagcactaaa ttcgctgtcg gataaccaat tgtacgacca cgagcattac
     2761 catgaaccac catacctctt gatggaagcg gtgcccccaa aagttttcct gcttctttca
     2821 catttccatc taaaatagct tgacggatac gagttgaact aatctttcct ttctcatctt
     2881 ctacaggtgg aacaatgata acttctccat caaagtaatc ctttaaatct tctgctgttt
     2941 ttttgtcaga accaaatgta taatcaaaac ctgcaacaat aattttggca ttcatagcct
     3001 tgatataagt tgcaaagaat tcttgtgcag tgagactagc gaattgacta ctaaaatcaa
     3061 ggagatataa ttcttctaca ccttcgcgct ttaattttct ttcacgttca gcagggttca
     3121 aaatatgcaa aaacaaatct ggatgataag gctctaaagc gatctttgga gattcattaa
     3181 aggtcataac gacgataggc aataaatcct ttctcgcagc cttgttggca acacgaaata
     3241 attcttgatg ccccttatgt atgccatcaa aatagccgag aacaacgact gaatcagatg
     3301 gtgtgccaat atctttttgg ttttttatag gaatagtaat aatcataaaa taattatatc
     3361 atagcgatag ctatttctgg aacagaaaat ctgaaatgtt gtttttttca catgaagtgt
     3421 acctgttttc aaaaggcact ttattctatc gttgcttaac tatgaacttt gcaatattct
     3481 tctcaaaaac ttgtaggaca tcttcaaaat tttgcaagga gtgattagac ttgttcggta
     3541 accataaagt gtcatactat gcttatgtat gaaaaagcaa tgcaactaac tcctgagaac
     3601 tttaaattac taattggtgc cgaaaaggta gaatttagaa tcgaggtaca cctatggctg
     3661 taaaatttac aaaatgagac aacttgggca agatgtttga agaatttcct aaactccctg
     3721 atttgaagca agtcactttc cctgatgaca aagaaaaaag ccaaagcaat aaagaaaaac
     3781 tagatgactg ctttccaaca actcccatct agtgtgcttc agactgggct atttttcttt
     3841 ccatctgtta gcttggattc tcagaccgtt tcagctaaag aatatctttt cctttatcag
     3901 aaggaacggc tcaagccatt cagacaagtg aagggacgac aagccaatat ttgaaaccag
     3961 gtagcagttc ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg aaacttaaat
     4021 caatttttag cagtgttcta ttccagattc atactcaatg aaaattaaag tgcaaactag
     4081 gaagttagcc gcaggctgta cttgagtacg gcaaggtgaa actgacgtgg tttgaatttg
     4141 attttcgaag agtatcaatc cactatacat attaaaaagt atgggtacca aaacaaaaaa
     4201 acaggctctc cgaaaactcg gaaagcctta ttttaagctg tttctagctt cctcaccttt
     4261 acatttcaag gttcgggata aaaggttcaa tggacctttt tatttagcga ttgggtaaac
     4321 agaaacttgt tttttatcgc gtcctttacg ttcaaagcgt actacgcctt caactttagc
     4381 gaacaaagta tcgtctccac cacgaccaac gtttacacct ggatagatgt gtgtaccacg
     4441 ttgacggtaa aggattgatc cacctgttac agtttgtccg tcagctgctt tagctccaag
     4501 acgttttgct tgtgaatcac gtccgtttga tgtagaacct ccaccttttt tgtgggcgaa
     4561 aagttgcaag ttgttaagag tcatttttaa cataatgttt tcctccgtgt tagttttctg
     4621 tgataactct ggtttggacg aactcagaat agttctccga taagtttgcc atacctaaga
     4681 aaaatgattc aaagaataac tgggtcattt ctctctggtg tgaaggaaga tcttttggta
     4741 tttcaaccat cagatagcca ccttcatctt cgtttaattc taggattggt tcatagcctg
     4801 caaatttctc aatagaattg ataaagttaa tggcaagcgt agaaaccgat gcacacacga
     4861 catctaagcc gtattcgcca ctctcggcgt gtccagtaat ttccgcactc ctcagctcgc
     4921 catcttcggc tctctcaaag actgcttgta tcatgtgttc tccttaaaat taagcgttaa
     4981 ttgcgttgat gacaactttt gtatatggtt gacggtgacc ttgtttacgg tggctacctt
     5041 ttttaggttt gtacttgtaa gtaacaactt tcttttgttt tccttgtttt tcaacagttc
     5101 caactacagt agctccagca acaagtggag ttccgacaac agtgttttca ccaccaacaa
     5161 gaacaacttc gttaaaagta acttcttgac cagcttcaac gttcaatttt tcaatgtaaa
     5221 ctgcttgacc aacttcaact ttaacttgtt ttccgccagt tttgataatt gcgtatgtgc
     5281 tcattatgca cctcctatga tttttatggg tttccccgat tttttgtgaa gactcgccta
     5341 gcatcgtggg acaaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca
     5401 caggatcgtg catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat
     5461 aacacctaaa atcaagcttt ttcttttact tttttctgcc actaggcaaa aagcatactg
     5521 agataaaaaa tgctcatcat aataggaaca ccaagaatgg tcttttcatg atagaaaatc
     5581 gtcaaatagg ctgaaaagac aacgccaagg acaaaactac taagcaggct aacaaatatg
     5641 aacccttcac gcaaaaaagg agtgtgctta gttcggaaat aatctccaaa agctagcatt
     5701 gttcgtttga tattccctgt cataaaggca ttattgtagg caatacccga aacctcacca
     5761 aaagcagttg tcaccagtcc catacagaag gccaagggct gcactagata gatattatct
     5821 acagtttgtg gcacaaaacc aataattatt gataggattg ctaaaggaat caaggacaga
     5881 ataggttttt tcacaattct caatttttcc ttataaatcg ttaataaaaa gactcccatt
     5941 ataaacgtta ttaaggttaa aagcttatcc ctaacatccg aaacattatt ttgtattagc
     6001 tctaccgaaa gaaagacaac atttccagct tgtccagcta caagggtatt ccctcgaaca
     6061 ataaaagtgt aagcatccac atatccagca caaaatgtca aaaaagtgct aaccttttag
     6121 actgacgtga tatttttctt ataggtaata acctcatttt ccctcccatt gtattttctc
     6181 ttagaaatat tgtaccattt ctttctaaaa aatcgtagac taccatttag attttactat
     6241 tagcataaaa ataatagaca actatttatc caaaaataga tagaggtaac atgtttgcaa
     6301 acaaagcata cgaaccttta gtaaaatcat ttccatgaaa ctagaataga gcccctctta
     6361 gcaaaaatca ttattttaat ttatttctaa tcactccttg acataaataa ctctcaccaa
     6421 taaaagacta tgtcttaaaa aaatggtata ataaaatcaa tacttgggct tgatggctat
     6481 gctactaata acaattagga gagaaaatca ggcacttgtt aacaacaagg attatcccct
     6541 tgagatgaaa ggaactttag aaatcttatg atgaacatgc aaaacatgat gcgtcaagca
     6601 caaaaacttc aaaaacaaat ggaacaaagc caagctgaac ttgctgctat gcaatttgtt
     6661 ggcaaatctg ctcaagatct tgtccaagcg accttaactg gcgataagaa agttgtcagc
     6721 attgatttca atccagctgt cgttgaccca gaggaccttg agactctttc tgatatgacc
     6781 gttcaagcca tcaactctgc tcttgaacaa atcgatgaaa ctaccaagaa aaaactgggt
     6841 gctttcgctg ggaaattacc tttctaaaaa caaggagcta gaacaatgct tgtcgataac
     6901 aaaggctaag aaaggtgcaa aaatg
//
LOCUS       DAVKZI010000073         6653 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKZI010000073 DAVKZI010000000
VERSION     DAVKZI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.074"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..512
                     /locus_tag="VXB18_002051"
                     /pseudo
     CDS             1..512
                     /locus_tag="VXB18_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            679..879
                     /locus_tag="VXB18_002052"
     CDS             679..879
                     /locus_tag="VXB18_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383190.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATISDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            921..1325
                     /locus_tag="VXB18_002053"
     CDS             921..1325
                     /locus_tag="VXB18_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383191.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1556..2263
                     /gene="ccdA2"
                     /locus_tag="VXB18_002054"
     CDS             1556..2263
                     /gene="ccdA2"
                     /locus_tag="VXB18_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0383192.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2274..2831
                     /gene="sdbB"
                     /locus_tag="VXB18_002055"
     CDS             2274..2831
                     /gene="sdbB"
                     /locus_tag="VXB18_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0383193.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3205..4596
                     /locus_tag="VXB18_002056"
     CDS             3205..4596
                     /locus_tag="VXB18_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0383194.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4739..5656
                     /gene="adcAII"
                     /locus_tag="VXB18_002057"
     CDS             4739..5656
                     /gene="adcAII"
                     /locus_tag="VXB18_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0383195.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5664..>6653
                     /gene="phtD"
                     /locus_tag="VXB18_002058"
     CDS             5664..>6653
                     /gene="phtD"
                     /locus_tag="VXB18_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0383196.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELE"
BASE COUNT         2062 a         1211 c         1392 g         1988 t
ORIGIN      
        1 aaacaggaga gttaaaccac caagtaaaag gaacaaaacc aagaaaagtt gatagagata
       61 gacttaaaaa ctatcttact gacaatccag acgcttattt gactgaaata gcttctgaat
      121 ttggctgtca tccaactacc atcactatgc gttcaaagct atgggctaca ctcgaaaaaa
      181 agaaccacac ctactatgaa caagacccag aaaaagtagc cttatttctt aagaatttta
      241 atagtttaaa gcacctagca cctgtttaga ttgatgaaac aggattcgat acttattttt
      301 atcgagaata tggtcgctca ttaaaaggtc agttaagaag aggcaaagta tctggaagaa
      361 gatatcagag gatttctttg gttgcaggtc taacaaatgg tgaattaatc gctccaatga
      421 cttacgaaga gatgatgacg agcgactttt ttgaagtatg gtttcagaag tttttcttac
      481 caacattaac cacaccatcg gttattatag taaaatgaaa taagaatagg acaaatcgat
      541 caggacagta aaatcgaatt ctaacaatgt tttagaagtc catatgtact attctagttt
      601 caatatacca taactgttcc tagtcaacct gcaagccctg tcccagctcc aagctcagct
      661 ccgactcaag atcctagagt ggtagcaagc gcttcggcta gctcaacgag cacacaagct
      721 caagagcaag ttgacaagtc tgaacttcgt gccttgagtc aagagttaga ccaacgcttg
      781 aaagctttgg caacaatatc tgatccgaaa atcgatgcaa ccaaggctgt cctcctagat
      841 gctcaaaaag ctccggaaga tagtgccttg acagagtaag gtctgcatac tgcagtagag
      901 tctgtgaagg ctgggctgcc ttggactctc tcaaagatgt gaaagcaaat gctagcgaca
      961 gcaagcctgc acaggacaag aaggatgcaa aacaaggaac ggaagatagt aaggattcag
     1021 ataagatgac tgaaacaaac tcagttccgg caggagtgat tgtggtcagt ctacttgccc
     1081 tcctaggcgt gattgccttc tggctgattc gccgtaagaa agagtcagaa atccagcaat
     1141 taagcacgga attgatcaag gttctaggac agctagatgc agaaaaagcg gataaaaaag
     1201 tccttgccaa agcccaaaac cttctccaag aaacccttga tttcgtgaaa gaagaaaatg
     1261 gctcagcaga gacagaaact aaactagtag aggagcttaa agcaatcctt gacaaactca
     1321 agtaaaacat gatttatgaa atgtcagacc taaaagacat tttcgttcac aaaagcagcg
     1381 atgagtaatc cttgtcgttg ctttttggct attttggggg ataagatccg ccttgactag
     1441 caaaagaaaa gattggtcca atagtgcccg atacgatttt gcgtagcaga aagcttacaa
     1501 ataaaattga atatagtaaa ataggattag aattattaag aaagttggtt ctttattgga
     1561 aacgatagta tttttaatct ctgtttttct agcaggtgtt ttatcctttt tttctccttg
     1621 tatttttcct cttctgccag tctatgctgg gattttattg gatgatcaag aaagtgcaaa
     1681 aagcttttct ttgtttggga gaaaggttct ctggtcaggc ttgattcgaa cactttgctt
     1741 tatcgctggt atctctctca ttttctttat tctaggcttt ggtgctggtt actttggtca
     1801 tattctctat gcaaattggt ttcgatatgg catgggagct attattatca ttttgggtct
     1861 tcaccagatg gaaatttttc atttgaagaa attagaagtt caaaaaagtt ttacctttaa
     1921 aaaatcagat tctaatcgtt attggtcagc ttttttactt ggtattacct ttagctttgg
     1981 ttggacacct tgtattggtc cagttttaag ttctgtttta gcacttgcgg cttctggagg
     2041 caatggcgct tggcaaggag cgatttatac tctcatttac actctgggca tggcccttcc
     2101 tttcttggta ttggcactag cttcaggtct agtcatgcca tattttagta aaatcaagcg
     2161 tcatatgatg ctactaaaga aaattggtgg tttcctcatt gttttaatgg gaattttgtt
     2221 actattagga caagtaaatg ttctagctgg aatttttgaa taaaggagga caaatgaaaa
     2281 aagtaatgtt tgctggctta agtctcttgt cattagttgt attgatggcc tgtggtgagg
     2341 aagaaactaa aaagactcaa gcagcacaac agccaaaaca acaaacgact gtacaacaaa
     2401 ttgctgttgg aaaagatgct ccagacttca cattgcaatc catggatggc aaagaagtta
     2461 agttatctga ttttaagggt aaaaaggttt acttgaagtt ttgggcttca tggtgtggtc
     2521 catgcaagaa aagtatgcca gagttgatgg aactagcggc gaaaccagat cgtgatttcg
     2581 aaattcttac tgtcattgca ccaggaattc aaggtgaaaa aactgttgag caattcccac
     2641 aatggttcca ggaacaagga tataaggata tcccagttct ttatgatacc aaagcaacca
     2701 ccttccaagc ttatcaaatt cgaagcattc ctacagaata tttaattgat agccaaggaa
     2761 agattggaaa gattcaattt ggtgctatca gtaatgcgga tgcagaagca gcatttaaag
     2821 aaatgaacta gaatcgataa aatctgatta caagatgtag tcagattttg gtaacttcta
     2881 aaactaactt ccagtttccc acaacctagc ttttagtatg agaaaaacgc gtgacatcag
     2941 tggaaatccg tcttagacta acttccactg gttttctttt tcttaatata taagggttca
     3001 aaagcgaaaa gactcagaaa aagtgcacga caaatagccc taaaacagag tcatctgaga
     3061 ctaacttcca gttttgggag agagatggaa gttactttga gaagttacgg tagtcagatt
     3121 tttttagaaa aacattttat aaatattcac atatctccta tatttatggt aaaatagaat
     3181 catcagttta ttttggagtc aaagatgaat atatttagaa caaagaatgt tagtttagat
     3241 aaaacagaga tgcataggca tttgaagtta tgggatttga ttttgctggg tatcggagcc
     3301 atggtaggga caggcgtctt tacaatcaca ggtactgcag ctgcaacact tgctggccca
     3361 gccctagtga tttcaatcgt tatttctgcc ttgtgtgtgg gattatcagc cctctttttt
     3421 gcagaatttg cctcgcgagt acccgctaca ggaggtgcct atagttacct ctatgctatc
     3481 ttaggagaat tccctgcctg gttggctggt tggttaacca tgatggagtt catgacagcc
     3541 atatcaggcg tagcttcggg ttgggcagct tattttaaag gcttgctctc tcaatacggg
     3601 atagcctttc ctcaggcttt aaatggtacc tttaatcctc aagcagggac atttgttgat
     3661 ttattgccta ttcttgtctt ggtcttggtg acttcgcttg ttttactaaa tgccaaggca
     3721 gccttacgct ttaattcgat tctagttatt ttgaaatttt ccgctttagc tctctttgtt
     3781 ttagtaggaa tttggaatat taagtttgat aattggagca attttgctcc ttacggtttt
     3841 ggacaaatct atggagctag cactggtatt atggctggtg cgtccttgat gttcttcggt
     3901 tttttgggat ttgaatccat ctctatggct gtagatgaag tcaagactcc tcaaaaaaat
     3961 attcctagag ggattgtctt atcgctttct atcgtaacca ttctctatgc cttggtgacc
     4021 cttgttttga ctggtgtggt tcactatagt catttaaatg tcgatgatgc cgttgccttt
     4081 gcccttcgta gtgttgggat tagttgggca gccaactatg tgtcattagt ggctatcttg
     4141 accttgatta cagtttgtat ttcgatgacc tatgccctat cgcgtatgat ttacagttta
     4201 gcacgtgacg gcttagtgcc tgctgccttt aaggaactga cgaagactag caagatacca
     4261 aagaatgcta ctatcttgac aggtctagct tcagcagtag cagcaggaat gttcccacta
     4321 gccagtattg cagccttttt aaatatttgt accttagcct acttgatcat gttggcttat
     4381 ggtctgattc gcttacggaa agaaaaagga atgcccaaag ctggggaatt taaaacacca
     4441 ttggtacctc tgttaccaat tttatcgatc atcatttgtt tatccttcat gttacagtat
     4501 aatatgaata cctggattgc tttcctagtt gcgttgttag taggaagtat tatttacttc
     4561 acttatggct ataagcattc taccatagaa gaataaagtg aaagtctatt gagttgttga
     4621 cactcagcag atttttatat gtgaaagaaa tttcaaattt tttctaaaaa tatcttgaca
     4681 gattaaattt tcaggagtag aatatttact agttaattaa atggttaagg agttgttcat
     4741 gaagaaacaa aatttatttt tagtcctgtt aagtgtcttt cttttgtgct tgggggcttg
     4801 tggtcaaaag gaaagtcaga caggaaaggg gatgaaaatt gtgaccagtt tttatcctat
     4861 ctacgctatg gttaaggaag tatctggtga cttgaatgat gttcggatga ttcagtcaag
     4921 tagtggtatt cactcctttg aaccttcggc aaatgatatc gcagccatct atgatgcaga
     4981 tgtctttgtt taccattctc atacactcga atcttgggca ggaagtctgg atccaaatct
     5041 aaaaaaatcc aaagtgaagg tcttagaggc ttctgaggga atgaccttgg aacgtgtccc
     5101 tggactagag gatgtggaag caggagatgg agttgatgaa aaaacgctct atgaccctca
     5161 cacatggcta gatcctgaaa aagctggaga agaagcccaa attatcgctg ataaactttc
     5221 agaggtggat agtgagcata aagagactta tcaaaaaaat gcgcaagcct ttatcaaaaa
     5281 agctcaggaa ttgactaaga aattccaacc aaaatttgaa aaagcgactc agaaaacatt
     5341 tgtaacacaa catacagcct tttcttatct agcgaagaga tttgggctta atcaacttgg
     5401 tattgcaggt atctctcctg aacaagaacc aagtccacga caactaacag aaattcagga
     5461 atttgttaag acctataagg ttaaaacgat ttttacagaa agtaacgctt cttcaaaagt
     5521 agctgaaact cttgtcaaat caacaggtgt gggtcttaaa actctgaatc ctttagagtc
     5581 agacccacaa aatgacaaga cctatttaga aaatcttgaa gaaaatatga gtattctagc
     5641 agaagaatta aagtgaggaa agaatgaaaa tcaataaaaa atatctagca ggttcagtgg
     5701 cagtccttgc cctaagtgtt tgttcctatg aacttggtcg tcaccaagct ggtcaggtta
     5761 agaaagagtc taatcgagtt tcttatatag atggtgatca ggctggtcaa aaggcagaaa
     5821 atttgacacc agatgaagtc agtaagagag aggggatcaa cgccgaacaa attgttatca
     5881 agattacgga tcaaggttat gtgacctctc atggagacca ttatcattac tataatggca
     5941 aggttcctta tgatgccatc atcagtgaag aacttctcat gaaagatccg aattatcagt
     6001 tgaaggattc agacattgtc aatgaaatca agggtggcta tgtcattaag gtagacggaa
     6061 aatactatgt ttaccttaaa gatgcggccc atgcggacaa tattcggaca aaagaagaga
     6121 ttaaacgtca gaagcaggaa cgcagtcata atcacaactc aagagcagat aatgctgttg
     6181 ctgcagccag agcccaagga cgttatacaa cggatgatgg gtatatcttc aatgcttctg
     6241 atatcattga agatactggt gatgcttata tcgttcctca cggcgaccat taccattaca
     6301 ttcctaagag tgatttgtct gccagtgaat tagctgctgc ccaagcctat tggaatggga
     6361 agcagggatc tcgtccttct tcaagttcta gtcataatgc aaatccagct caaccaagat
     6421 tgtcagagaa ccacaatctg actgtcactc caacttatca tcaaaatcaa ggggaaaaca
     6481 tttcaagcct tttacgtgaa ttgtatgcta aacccttatc agaacgccat gtagaatctg
     6541 atggccttgt tttcgaccca gcgcaaatca caagtcgaac agccagaggt gtagctgtcc
     6601 ctcatggtaa ccattaccac tttatccctt atgaacaaat gtctgaattg gaa
//
LOCUS       DAVKZI010000074         6366 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKZI010000074 DAVKZI010000000
VERSION     DAVKZI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.075"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            144..1913
                     /locus_tag="VXB18_002059"
     CDS             144..1913
                     /locus_tag="VXB18_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0383197.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            1937..3892
                     /locus_tag="VXB18_002060"
     CDS             1937..3892
                     /locus_tag="VXB18_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0383198.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            3894..4331
                     /locus_tag="VXB18_002061"
     CDS             3894..4331
                     /locus_tag="VXB18_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0383199.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4393..5529
                     /locus_tag="VXB18_002062"
     CDS             4393..5529
                     /locus_tag="VXB18_002062"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0383200.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1956 a         1078 c         1293 g         2039 t
ORIGIN      
        1 gatatgatgc gttttatcat ttttaagcct ttttgcccag cctcgtcaaa agtaatgttt
       61 tgacacaaaa tttgtgacaa aactttagtt ttaaaggttt ttaactttgt atatactagt
      121 tttaagaaaa ggaggatgat ctaatggaag aaaaagtatc attgaaagtc agggttcaaa
      181 aactagggac atcgctttca aatatggtta tgcccaatat tggagcattt attgcttggg
      241 gagtattgac tgccctcttt atcgctgatg gctatctgcc aaatgaacag ttagctactg
      301 ttgttggtcc tatgttaacg tatttattgc caatcctgat tggttacaca ggtggatata
      361 tgatccatgg ccaacgtggt gccgttgtag gagctattgc tactgttggt gcaatcacag
      421 gttctagtgt tcctatgttt atcggagcta tggtaatggg cccactggga ggatggacta
      481 tcaagaaatt tgatgagaag ttccaggaaa aaattcgtcc cggatttgaa atgttagtta
      541 ataacttctc agctggtctc gttggttttg cattattgct tttggctttc tacgcaatcg
      601 gtccagtcgt atcgactctt actggagctg ttgggaatgg tgttgaggct attgtcaatg
      661 ctcgcctcct tcctatagct aatattatca tcgaaccggc taaagtcctt ttcctcaata
      721 atgccctcaa tcatggcatt tttactcctc tgggagtaga acaggtagct caagctggta
      781 agtcaattct cttcctattg gaagctaatc ctggaccagg cctgggaatt ctattagctt
      841 atgctgtatt cggtaaaggt tctgctaaat cttcttcttg gggggcaatg gttattcatt
      901 tcttcggagg gattcatgaa atttactttc cttatgttat gatgaagcct actctatttt
      961 tagctgctat ggcaggaggt atctctggaa cttttacttt tcaactctta gacgctggtc
     1021 ttaaatctcc agcttcacca ggttctatta ttgcgattat ggctacggcg ccaaaaggtg
     1081 tttggcccca tctaaatgtt cttctaggtg ttttagtggc agcagttgtt tctttctttg
     1141 tagcagccct tattcttcat gcagacaagt caactgagga ttcgctcgaa gctgctcaag
     1201 aggctaccca agcagctaaa gctcagtcta aaggtcagtt agtatcaact tctgttgatg
     1261 cagttatttc gacagactca gtggaaaaaa tcattttcgc ctgcgatgct ggtatgggaa
     1321 gctctgctat gggagctagt attcttcgag ataaggttaa aaaagcaggt ctagagattc
     1381 cagtatctaa tcaggcaatc tcaaatttgc ttgatacacc aaaaacatta attgttactc
     1441 aggaagaact gacaccaaga gctaaagaca agagtccaag tgctattcat gtttctgttg
     1501 ataatttctt agcgtcccct cgttatgatg aaattgtagc ttcattaaca ggagcttttc
     1561 caatagcaga aattgaagga gatataccaa cttcagcacc agtagatagt caggaaattg
     1621 accttaacca tattgatgct gtagtagttg cttatggtaa agcacaggga actgcaacta
     1681 tgggctgtga aacgattcgg gctatcttta gaaacaagaa tattcgtatt ccagtttcta
     1741 ctgccaaaat ttcagaatta ggtgaattta attctaaaaa cataatgatt gtaacaacta
     1801 tttctttaca ggcagaagtg cagcaagcag caccgaattc tcaatttctt attgtggata
     1861 gtttagtaac aacaccagaa tatgacaaaa tggctgctag aatgtacaaa tagaactaga
     1921 ggtttctaaa ttacgaatgc tattaaccaa acgagaagaa caattattga aggctttcct
     1981 acatgtaggg aagctttcaa tgcaagatat gactgaaatc ttacaggttt catctagaac
     2041 aatttatcga actttatcag atttgacaga tagcatggag caatatggaa tcgaaataac
     2101 gaagcatggg aaatactata ttttgactgg agagttggat gatttgccga cagaacttga
     2161 agtgttagtt gagtatagtc cccaagaaag acaagagttg attacctatc gccttctgac
     2221 tgagagtggt tttgtcacca atgaagcatt gcaagagtgc acgaaagtca gtaatgtaac
     2281 tattattcag gatatttcag atattgataa gcgtctttta gactttgatc tgaaaattga
     2341 acgacaaaaa ggttatcgga tttctggtga ttcagttggt aagagaagat ttttggctat
     2401 tttactgaca aactgtatct cagtagcaga tttttcaacc ggtaattttg ggagctttga
     2461 tattttagaa gcagatagaa ctaggctggc cagtcagatt gttaataagc aactgtcagg
     2521 ttttccagat atggatgcta ggatgaagat gttttttgcg atcttgttat ctcttatagg
     2581 tcaggagcaa aacattgaaa attcacctaa tactagtaag caggctttgg aaatttctca
     2641 aaaaattttt caagcttact ctaagcagac tgcacaattt tatagtattc aggaaattat
     2701 ctattttgcg agcatcttgg atgaattaat cattaaacgt caggacaatc cgctctttac
     2761 ggagaaattt gatggtgaat ttttctacaa tatttcaaat ctgattgata cggtttccat
     2821 gtataccaag attgactttt ttaaggacaa ggttttattc aattttcttt tccatcatat
     2881 tcggctcagt ttaggcgtcc ctatcctttt tcagggtgaa aatttgccag aatctgtcca
     2941 gattttagtt gaaaggaata aatttcttta tacagtcatc agtcttttag tgaatgatat
     3001 ttttccgaaa tatcttcata cagagtatga gtatggcatg attgccctac attttatctc
     3061 tagcttaggc cgtagtccag agatttatcc agtccgtgtt ttgcttttaa cggatgaacg
     3121 tcgggtcact agagatttat tagtcagtaa aattaagagt gttgctcctt ttgtagagtt
     3181 gatagatatt cagtctctag tagattacca cagtattgat ctcagtcagt atgattatat
     3241 tttatctacc aagccgctga ctaatcagga aatcgatgta atttctagtt ttccaaccgt
     3301 caaagaattg cttgaattac aggaacgact tcagtatgta caggcacatc gtacaattgt
     3361 cgcgcgtgat gctatcgctc cagagaaaag ttatgacttg caagattatt taatatctag
     3421 tagtcagctt ttgagtcaat tcgagttggt tcaattggag aataatcaat catttgagca
     3481 cacggtagaa caaatcatcc aatatcagaa gaatgtgagt gacagagatt acctaacaag
     3541 aaaattgtta tctcacttcc agaatagtcc tatggctatt cctaatactg gtctggtgct
     3601 tttacatagt cagtctagca aagtaacaac aaatagtttt actatgtttg aactcaaact
     3661 acctatctcc gcattgtcaa tgaaacgaga ggaagaagag gtcaaaaggt gtctgctaat
     3721 gctaatgtct aaagaagcta gcgaggaagc gagagattta atgacagcta ttagtcagtc
     3781 gattattgaa aatcatcttt atacagagat ttacaagacg ggaaatcaat ccattattta
     3841 tcagatgcta aatactattt ttaacgaaaa aattaagaaa ttggagaact aatatgaaac
     3901 ttgaaaaaca tttgattaag cttaataaac aattttctaa caaggaggaa gctatttgtt
     3961 attgtgggca agttctttat gagggtggat atgttaatga agactatatt gaagccatga
     4021 ttgagcgaga taaagagcta tctgtttaca tgggtaactt tatcgcaata ccgcatggaa
     4081 cagatgcagc aaaaaaggat gtcctcaagt ctggtattac agtcgttcaa gtccctagag
     4141 gggttgattt tgggaatgta tctaaccctc aagtggcaac ggttcttttt ggtattgctg
     4201 gtattggtaa tgaacactta gaaattattc agaaaatttc tatcttctgt gcagatgtag
     4261 ataatgttct taaattagcc gatgctcagt caaaagagga agtattgcgc ttatttgatg
     4321 ctgttgaata attgaatttc gtcatttgcc atctagtata tatgtccctc aaataggaaa
     4381 aggagaaatt gaatgaaaca ttctgttcat tttggtgccg gtaatatcgg tcgtggtttt
     4441 ataggtgaaa ttctatttaa aaatggtttc catattgatt ttgtggatgt caataatcag
     4501 ataattcatg ctctaaatga aaagggcaag tatgaaattg aaattgcaca gaaaggacag
     4561 tctcgtatag aagtaactaa tgtggctgga attaatagca aagaacatcc tgagcaagtc
     4621 attgaagcga ttcaaaagac ggatattatt actactgcaa tcggacctaa tatactccct
     4681 tttatcgctg aacttctagc caaaggaatc gaagctcgcc gagttgcagg gaatacacag
     4741 gtattggatg ttatggcctg tgaaaatatg attggcgggt ctcaatttct ttatcaagaa
     4801 gtcaagaaat atttaagtcc ggaaggtttg acatttgctg ataactacat aggttttcca
     4861 aatgctgcag tagacaggat tgttccagca caaagtcacg aagattccct ttttgttgtg
     4921 gtcgagccct ttaatgaatg ggtcgtggaa accaagcgtc ttaaaaatcc agatttacgt
     4981 ctaaaagatg tgcattatga agaagattta gaacccttta ttgagcgaaa acttttttca
     5041 gtcaattctg gacatgcaac ttcagcttac attggtgcgc attatggtgc caagacaatt
     5101 ttggaagctc ttcaaaatcc taatattaaa tctcggattg aatctgtatt agctgaaatt
     5161 cggagtctct tgattgccaa atggaacttt gataaaaaag aattggagaa ttatcacaaa
     5221 gtcattatag aacgatttga aaaccctttc atagtggacg aggttagtcg cgtagctcgt
     5281 actccaatcc gaaaattagg ctataatgaa cgattcatcc ggccgatacg tgaattgaaa
     5341 gaactcagtt tgtcatataa aaacctactt aaaacagttg gctatgcctt tgactatcgc
     5401 gatgtaaatg atgaagaaag tattcgatta ggtgaattgt tggctaaaca atcagtcaaa
     5461 gatgttgtta tacaagttac aggtttagac gaccaagaat tgattgagca aattgtagag
     5521 tatatttaat atttttcgaa aatctcttca aatcaggtta gcatcgcttt gtcttaggca
     5581 tatgttactg acttcgtcag ttctatctac aacctcaaag cagtgctttg agctgactcc
     5641 gtcagttcta tctacaacct caaagcagtg ctttgagctg actccgtcag tcttatctgc
     5701 aacctcaaag cagtgctttg agctgactcc gtcagtctta tctgcaacct caaagcagtg
     5761 ctttgagctg actccgtcag tcttatctgc aacctcaaag cagtgctttg agctgactcc
     5821 gtcagtctta tctgcaacct caaaacactg tttgagttat ctgcggtaat ctttctagct
     5881 tgtctttgat ttttgttgtt atttataagg taaaagaagc tggacaaaaa gtcttcaaaa
     5941 tcggaaaaag gcagcctatc gggtgttcaa aaatcttgat aggatgtcct ttattatgga
     6001 aagccttatt ggattttctc ctcagattga gtttttgatc agctttatga gataggtttt
     6061 gctagagatg tagcccatca tgttattttt atggacggtg ggaaaattgt tgaaaaaaat
     6121 aatgcccatc aattctttag tcgtccaaga gaagaacgaa ccaagcaatt ttggaacgaa
     6181 ttctttcgaa tgcgatctat atagtaaaat gaaacaagaa caggacaaat cgatcaggac
     6241 agtcaaagcg atttctaaaa atgttttaga agtagaggtg tactattcta gtttcaatct
     6301 actatataac tgaaaaatta gataaattag ttttggaaaa tgactaacca aaagatatcc
     6361 aaagta
//
LOCUS       DAVKZI010000075         6324 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKZI010000075 DAVKZI010000000
VERSION     DAVKZI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.076"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(341..1567)
                     /locus_tag="VXB18_002063"
     CDS             complement(341..1567)
                     /locus_tag="VXB18_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0383201.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTIISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1639..2304)
                     /locus_tag="VXB18_002064"
     CDS             complement(1639..2304)
                     /locus_tag="VXB18_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0383202.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2371..2571)
                     /locus_tag="VXB18_002065"
     CDS             complement(2371..2571)
                     /locus_tag="VXB18_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0383203.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            complement(2857..3720)
                     /locus_tag="VXB18_002066"
     CDS             complement(2857..3720)
                     /locus_tag="VXB18_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0383204.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDPIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFK
                     LRLQQYKALID"
     gene            complement(4115..5287)
                     /locus_tag="VXB18_002067"
                     /pseudo
     CDS             complement(4115..5287)
                     /locus_tag="VXB18_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(5300..6049)
                     /locus_tag="VXB18_002068"
     CDS             complement(5300..6049)
                     /locus_tag="VXB18_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0383205.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFQYVSDSSMVGYMGKTKELKMYQEELDKKHYIDRISSISCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            complement(6061..6284)
                     /locus_tag="VXB18_002069"
                     /pseudo
     CDS             complement(6061..6284)
                     /locus_tag="VXB18_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816181.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2177 a         1179 c          989 g         1979 t
ORIGIN      
        1 caaaacaccg ttttgaggtt gtggatagaa ctgacgaagt cagtaacata tatacggcaa
       61 agtgaagctg acgtggtttg aagagagttt cgaagagtat aagtaggctg aaaagaatcc
      121 agccacagca tggactatta tatagcagat tgaaataaga tgagaacaaa tcgattggga
      181 aagtaaaatt aatttctata aatgttttag caattgtttc gtactatttt agattcagtc
      241 tattataaca cattcagaaa agagaaaaaa gtctgttgat tttgaccatc ataaaaagac
      301 tggcaatcca gtctcaaaca tatattatag aaattctcca ctaaatactt tcacgaatat
      361 tcagaagcat aacaaaggca actagaagaa atagcaataa aacaaagcta actgccagag
      421 ttccaaagct agtagcaatg gttaccaaag ctattgtaaa taagctaggt aaaacaaccg
      481 taatggcacc gatagaggat tgaactgctc ccattgactc ctcaggtatt tgtttaaaga
      541 cgagttcttg caatctagga gagagaacac ctgcgaaaaa ggcatccaag gtactaaaga
      601 tgagaatcca gtcaaaacga actgtggcaa atcctactag aagaagcaac tggatgacaa
      661 gtgaggcata gagagctgtt tttatggaaa tggtatgttg cagatagcca cttacaaggc
      721 ttccgacaat cagggctgac agttcaaaag tggatagcaa ggcaagagat tgacctgttt
      781 gtaaattcaa aaagggttga ttcctcaaaa atagagtaga gacaggaact gtaacattta
      841 tcactgcttg actagtagag ataataaaca aaaccaagag caccttattc atattccata
      901 tcaatttcga tgattggagc aaatgctggc aaaaggattt tacagagagt ccttcttgat
      961 agttaatcgt tttttctact ttcaagaggt cagtttttat gaagaggata cctaaaaatg
     1021 cgattaaaaa ggtaagagcg ttcagcaagg aaatgaactg gatggagaga atccctagca
     1081 agactcctcc tagaatatta ctgattgttt tcactaaact aacagttgac tgtttaaatc
     1141 caatagcttc tgccagatgg tcttgcccaa taattctaat gaaaatcgga gtgagcatgg
     1201 ctcctgaaaa gtaactcaat gtgtcagaca agaggttaat cagacaaata aatgctacta
     1261 gcaacaagga gaaagactgc cctgaaagcg atagggacac tatagagtaa agcaaaaatt
     1321 ttgcaaaact aataattgta tattttagga cacgatgatg ttgaaaatct gccaaaactc
     1381 ccagaaagat ttgtagaact tggggaaggg tttctgaaat cgtgataagt aaaatcgcca
     1441 aaggggcaaa agacgcatct gctacataat tcaaaaaggc cagataaaaa atcgtatccc
     1501 caagcgttga aatccactgg ttgatagtta attgcctaaa atctctattt tgaagaaata
     1561 ctttcatcac aactccttct taagttcaaa tgggaatctt tccccaagga tagaccgcga
     1621 tactactaac aaccaaaatt acagtaacat caaaagctga ccaatgccat tgtagactat
     1681 atgcagtcca ataggccaat aaattgactt tgtcattcta aataagactg caaatataag
     1741 acctccaccc atatagaaga caaagtctgt caagacccaa ccgtgattac taatgtgcga
     1801 gaccccaaat aaaacagcgg aaccaagtac atctagcccc catttctttc ctttttccag
     1861 agctgtcatc accaatcccc gatggattat ctcttcaaaa atgggacctg caatcacagg
     1921 atagaaaaaa tacatcaaaa atgctgtagc ccctgtaaaa gtcggagcag catgttgata
     1981 agaaatttca tttcgagtag gtgggaaaag aaaaaaggta acgaaattcc aaacaacaaa
     2041 agcaagcaga gctaggaagg aatagaaaag ataggatcct ttaaactttc tactattgat
     2101 tttctgccat ttccccgacc aaatcatagc aataagagca aataaaacca caagaaaatt
     2161 caacatcata tccgacagat aataggcaaa gtcagatagc ccagtaacaa ggtcgctgcg
     2221 taaaactaga acactgaact tctggtcagc aataactagt agaaaaacta taataaagta
     2281 gcggtgtgag attatctttt tcattctatt tcctcctata ctatgaaata aagacagccc
     2341 ctacccaaga aaaggcaagg gctttggata ttaataacga cggcggtcag aatcaaagtc
     2401 aggtctatcg ttaaaatttt tcttccagaa attagtgatt gaccaaggtg tcccgaaccc
     2461 tccccaagca ccggctggga taacagcatt attcccaaat tcccctccat aaactgtctc
     2521 caactcagct tctgtcaatt ccattgtttc tgcaaattgt aaatttaaca tcttttacac
     2581 tccttcaatt atcttcattt gtaaaccact tctgcgacct aggatttgct tcaagtgctt
     2641 tacaagtaca gtataacacg aaaattggct tattttagaa aatcgcatat ttgatatttt
     2701 ttcttataga aatttcagat ttgcgatttt ggtatatttg attatttccc tggtataata
     2761 aagttattac taatgaggag ggaagtcata tgaagaaaca agttttaaca ttattgacaa
     2821 tcgttgctga gattattatc tttttcccat ttctaactaa tcgataagtg ctttgtattg
     2881 ctgtaagcgt agtttaaaaa gggctgttaa ttgtggattt tctaatactt gcagagattg
     2941 gataaagtgt tcaatctctt tttgattgct tcccttagtt tgaaggaaaa tgctcatctt
     3001 ctttaaaaac tgccacaata atttctcaaa aacatcgtat ggacggagca tactctccag
     3061 ctcggcttca aagattggga tataagaaaa aagtttgcgc tccatgagct ctgagatgat
     3121 atttaagagt ccttgcttca tatacaatcg attgtgtact aactctttaa attctttgga
     3181 tttttcgagt aaggaggttg ataaaaagat cggatcttga ttgctcaaga agggcatagt
     3241 attgcaaaag agatagagtt caaaccaggt ccaagactcg atagcataga gataggtggt
     3301 caaaaactcg ctatcctcct ctgctagtgg gtagctttta tctagtgagt ggatggcatc
     3361 tttgattaca atagcattca aacgacgata agtctctgcc atctgttctt gctcgacttc
     3421 ctccaacagt tgctctaagc cagctatatc ttgatgagca aagcgatcca caacctttct
     3481 accaatctgc atatgtggag attcttgata gttgttgagc ttgtgcccaa actcatcaaa
     3541 ggtcacattg atcccttgga tggctaatat gagcttatcc gcagacagca tagactgccc
     3601 tagttcaaac ttggacaact gagaagctgt tagaccctca caagccacat ctgtctgctt
     3661 aagctttctc gccaaacgta attccttgta aaattccccc agttccattt tttcaatcat
     3721 cctaccacct cctagctttt gcatattata tcattatttg tgttcatttg tcaaaacatt
     3781 ctgacacttt ggtgattgaa aaagccagcc ttaagctgac tctaaaagga ccgagccttg
     3841 tacaatacag aactcaatcc tcgttctaaa tagaatgtct aacttttttg ggcagtacac
     3901 gagcttgggg aacagccact ggaacgatga ggtgtgagct caaaatatcc tccaattatg
     3961 tttttcctaa tagcataccg gaagagtgaa aggattttat aatggagcgg ttacaaagaa
     4021 cctactttct attaaacagt atactatgaa aatgtgaaaa tttaacattt ttttgtacaa
     4081 attttataaa ttattgcctt tttaatatca atagttaatc tcttatccag attccccttg
     4141 tgtaaacttt atctttataa gcttcaaggc ccctattcca tctatttgca acaattagat
     4201 cactttgttt tgtaaatagt tcaaaattct tttcaaaaat tacgttatct atactaacgt
     4261 ttaaatttgg ttcatatact aaaattttta taccgacaat caatagttca ttaattatac
     4321 ttaaaatagc tgactctttg taattatctg aattatattt catccccaat ttatatattc
     4381 ctactatctt tggctttcgt tccaatattt gtttaactat gaactgtttt ctatttgtgt
     4441 ttgaaatatc aatcgcttct atcactgggg catttatttc tataaattct ttttttaatt
     4501 gtttagtatc tttgggaaga caatatcctc caaattcaaa agaaggatta ttataaaaat
     4561 ttccaattct tggatctaaa caaacacctt ttattacaac ttcagcattt aaacttctcc
     4621 tctcagcaaa aaaatctagt tcattaaaaa aagcaacacg gagagctaag aatgtgttag
     4681 aaaaaagctt aattgcttct gcttcagtag gagaaactaa cataacattt ttaatattgg
     4741 cagtactatg agtactaatc gaaaggaaca actctgcaat ttttcttcct tcaactgtct
     4801 catctccaac aactatgcga cttggatata aattatcata tatagaacaa ccttctctca
     4861 aaaattcagg gacaaaaatg atattttttg tatcaaacag cctttttaat ttgtttgaaa
     4921 agccgatcgg aactgttgac tttcaaataa tctttccatt aggttttacc ctcagaatct
     4981 tcgataccgt ttgttcgatt tcatatgtat taaaactacc aattttctca tcataatctg
     5041 tcggaagcgc aataatataa taatcaatat tatttttaat ttcagaaaat gtatcaaaaa
     5101 aagtaatatt taagttattc tcgcaaaaaa acttcataag ctcttcattt ttagatggaa
     5161 gaatgtcctt ttttaaatta tttattttta cagaatctat atcatatgca acaactttat
     5221 atttagatgc aaatagtaac gcgtaggcca gcccaacatg ccccaaacca attactgcta
     5281 tattcataaa actacttcct tatttcttaa tccaaaatct aatagaataa gctgccccat
     5341 tccttaaata caactcttta atattgttta aaagtttttc aactgatttc cagattatca
     5401 aaatctgaga tttatagcac gatattgatg atattctatc aatataatgt tttttatcaa
     5461 gttcctcttg atacattttt aattctttag tttttcccat ataaccaacc atactactat
     5521 cacttacata ttggaagtcc tcataatata ttactttata acgcataaat tcaagcgccc
     5581 ttccaatact attcacaaaa acatgatcaa catggtcacc aagtgaaagc ggacaatata
     5641 cgacacattt gtcgtctaaa tgcattaaca gctcttttat gatatcattc tttaatgtgt
     5701 cctcattttt taattcacta tagatatgac ggtatagaaa attgccattt ctatctttcc
     5761 tatagagaca ttcatagtac gataagtgtc taaaatcaca ttgtagacgt tcacaagcta
     5821 acctgtcttc tttcttcctt tcttcaatcg gatatttccc aaggttacac aacttatgaa
     5881 attgcttagc agagggctgt agctgttggc tcaaagggta accagaaaat atagtaataa
     5941 caagtacaat ttctccttct gaagttaatt ttgaaatata atcaccacag gaaaaaattg
     6001 cgtcatctaa atgtggagat aaaaagatat acttagtatt gttactcata accattccct
     6061 ctacaattta tctaaaaact cactaagtgt ctgattaaat tccacatcat caaaaaaatt
     6121 caccttattc ttaataatga atatttcgtt aaataaacat atatataaat atttcaatat
     6181 cctttcaata tcatcctcta attctcctca atattttgta tcagcccatt tacaatctta
     6241 ttaaaaaaga taagctcttt atctctaaaa ttaaatattt tcatacaact gttgtatcga
     6301 aaaatatata aaataatttt tact
//
LOCUS       DAVKZI010000076         6040 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKZI010000076 DAVKZI010000000
VERSION     DAVKZI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.077"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            70..312
                     /locus_tag="VXB18_002070"
     CDS             70..312
                     /locus_tag="VXB18_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0383206.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            314..568
                     /locus_tag="VXB18_002071"
     CDS             314..568
                     /locus_tag="VXB18_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0383207.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            615..1310
                     /locus_tag="VXB18_002072"
     CDS             615..1310
                     /locus_tag="VXB18_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV0383208.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(1647..2633)
                     /locus_tag="VXB18_002073"
     CDS             complement(1647..2633)
                     /locus_tag="VXB18_002073"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0383209.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2827..5295
                     /gene="gyrA"
                     /locus_tag="VXB18_002074"
     CDS             2827..5295
                     /gene="gyrA"
                     /locus_tag="VXB18_002074"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0383210.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5295..6038
                     /gene="srtA"
                     /locus_tag="VXB18_002075"
     CDS             5295..6038
                     /gene="srtA"
                     /locus_tag="VXB18_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0383211.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         1906 a         1002 c         1312 g         1820 t
ORIGIN      
        1 ctttttatat tgactgaaca cctaaaaagt aatacaatgg tgttaccatt aaaaaaggga
       61 gcacaaaaga tgactactat tacattaaaa gtttctgaag ctgataaaac atttatgaaa
      121 gcaatggcta agtttgaagg agtttccctt tcggaactta ttcgcaccaa aactcttgaa
      181 gccctagaag atgaatacga tgctcgtgtg gcagatttag cctatcaaga gtatttagaa
      241 gacttggaaa aaggagttga acccattact tgggaagaaa tgatgcatga tttaggcttg
      301 aaggatgaat aatttgtata aattagttcc aacaagacgt tttatcaagc aattgaaaaa
      361 attggaccgt tatacgcaga agctaattac aaactattta caaaccaatg ttttggaaga
      421 cccaagacga cacggaaagg ctttggttgg taatcgcgtt ggtcaatggc gctatagaat
      481 tggtaattat cgagttatcg tacaaattgt agatgatgaa ttagtcgttg ctactctaga
      541 agttggtcat cggagagata tttattgaat taaagctgag taataacagt atagaaagta
      601 aggagagtaa aaatttgaag aaaaaatggt tttttgcaga ttattatgac acaacaatta
      661 ttttacttgc tttaatctct gttattctgg tattacttgg atttgctgag atgactgatt
      721 tggacaatcc gccttatagt attattgatt tagtaatctg gggtgttttt gtaattgatt
      781 atagttggcg cttttttatt actaaaagaa aatggcgctt tattcttgaa aatatttttg
      841 atttattgac cattctccct ttaaatgcta tttttacagt gtttcgatta ggacgtatct
      901 tccgcttagc aaggctgaca aaattactga aactgactcg tttacttaga ataattggac
      961 ttacaggtaa actagaaaga aaaattagta gattcttacg aacaaatgga ttgatttata
     1021 tcttgtatgt taatatcttt attgttctag tagggagttc gattttatcc gttgttgaag
     1081 aaaaatcctt ctcagatagt ctttggtggg ctcttgtgac agtaactact gttggttatg
     1141 gtgatattgt tccagtttcc ctttttggga aatggctagc agttttactg atgcttgtcg
     1201 gtattggaac aatagggatg ctaacaagtg ctttgacgaa cttttttgta aaggataatc
     1261 cagatgaaca gataaaactt gataaactca aagacgaatt atcgagctaa agaatattaa
     1321 tagagaaaca atctgaaaaa atcgaagaac tacattgaat gataaaagac ttagttgaaa
     1381 aaatatcata aaggtgagac aaaataaaac ttgattcgag gagaaatcaa gtaagtcttg
     1441 acacaataga acgcatatta tcaggtataa aaacttgata ctatgcgttt tatagagaaa
     1501 taaaataaaa tctgaacaaa tcaattagga atttaaagca ttttataaca acgttttaga
     1561 gtgatggggt gctatttcaa cttcaaccta ctataataca gaaaaaaaca actccctgat
     1621 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     1681 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     1741 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
     1801 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
     1861 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
     1921 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
     1981 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
     2041 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
     2101 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
     2161 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
     2221 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
     2281 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
     2341 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
     2401 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
     2461 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
     2521 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
     2581 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
     2641 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
     2701 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
     2761 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
     2821 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
     2881 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
     2941 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
     3001 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
     3061 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
     3121 atgcttgtag atggtcatgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
     3181 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
     3241 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
     3301 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
     3361 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
     3421 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
     3481 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
     3541 gtcctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
     3601 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
     3661 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
     3721 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
     3781 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
     3841 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
     3901 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
     3961 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
     4021 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
     4081 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
     4141 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
     4201 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
     4261 aaacgccgta cagagttgat ggttggacag atcttgagtc tcgaggatga ggacttgatt
     4321 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
     4381 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
     4441 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
     4501 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
     4561 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
     4621 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
     4681 attgtgaaga gaactagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
     4741 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
     4801 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
     4861 atgagccgta tcgccactgg tgtgaaaggg gttaaccttc gtgaaggaga cacagttgtt
     4921 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
     4981 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
     5041 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
     5101 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
     5161 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
     5221 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
     5281 gaaggtgaag cataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
     5341 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
     5401 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
     5461 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
     5521 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
     5581 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
     5641 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
     5701 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
     5761 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
     5821 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
     5881 gagatggggt taatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
     5941 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct aatgaaatcc
     6001 taacagcttt caatcaacca tataaacaat tttattaata
//
LOCUS       DAVKZI010000077         6019 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKZI010000077 DAVKZI010000000
VERSION     DAVKZI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.078"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..1149
                     /locus_tag="VXB18_002076"
                     /pseudo
     CDS             1..1149
                     /locus_tag="VXB18_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1265..2068)
                     /locus_tag="VXB18_002077"
     CDS             complement(1265..2068)
                     /locus_tag="VXB18_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0383212.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2353..3108)
                     /locus_tag="VXB18_002078"
     CDS             complement(2353..3108)
                     /locus_tag="VXB18_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0383213.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(3178..5829)
                     /locus_tag="VXB18_002079"
     CDS             complement(3178..5829)
                     /locus_tag="VXB18_002079"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0383214.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKNLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5841..>6019)
                     /locus_tag="VXB18_002080"
     CDS             complement(5841..>6019)
                     /locus_tag="VXB18_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0383215.1"
                     /translation="ESLKLKHSRYYISKISKYDLKYNPGNYTMSPLAAFAEIEEIYIE
                     LSKIGLVKIVNKSN"
BASE COUNT         1849 a         1245 c         1155 g         1770 t
ORIGIN      
        1 atgattaaat tgattgatcg ttacggaata gagttcgtca aaaaagggaa aaatcgttac
       61 tattctcctg atttaaaaca agaaatgatt aataaagtct gacatgaagg ctggactaaa
      121 gatagagttt ctcttgaata ctgcctccca agtcgtacga tacttcttaa ctggctagca
      181 caatacagga aaaacgggta tactattgtt gagaaaacaa gagagagagt acctgagatc
      241 ggagaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaaa aagagaaaga
      301 agaaagacag aaattgttca agaattaatg actgagtttt cgttagatct tcttctaaaa
      361 gccattaaac tagctcgttc gacctactac tatcacttga aacagctaga caaaccagat
      421 aaggaccaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa gggaaattat
      481 gcttatcgct gtattcattt agaactaaga aatcgtggtt atctggtaaa tcataaaaga
      541 gttcaaggct tgatgaaagt actcaattta caagctaaaa tgcgacagaa acgaaaataa
      601 aggagacgtt ggtaagaagg cagagaatct cattcaaggc caatttgaag gatctaaaac
      661 aatggaaaag tgctacacag atgtgacaga atttgccatt ccagcaagta ctcaaaagct
      721 ttacttatca ccagttttag atggctttaa cagcgaaatt atcgcctata atctttcaac
      781 ttcacccaac ttagaacaag tacaaacaat gttggaacag gcattcacag agaagtacta
      841 cgagaatacg attctccata gtgaccaagg ctggcaatac cgacacgatt cttatcatcg
      901 gttcctaaga gtaagggaat tcaagcatct atgtcacgca agggaaacag ccaagacaac
      961 ggtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttatgg ctatgagaaa
     1021 acatttaaat cacttaatca attggaacaa gctattgtag actatattga ttactacaac
     1081 aataaacgaa ttaaggtaaa actaaaagga cttagccttg tgcaatacag aactaaatcc
     1141 ttcggataaa ttatttgtct aactttttgg ggtcagtaca cctaaaactt tgatgatata
     1201 cgttttcttg tgagaatatt tacttcattt ttgcctaaaa ttcaatgttt actcagtatt
     1261 tggattatga aaaatcgagg tctaaatcta gatacatttt ttctgaagac aaatcatttt
     1321 gaccaccgag caagagattt tcaaaaaaag ctgttaaaaa ctcagaacgt cgctgtaaaa
     1381 tctttgcatt atctaatacc aaggcatcac gaaaatattt ggaatgttgc tgaaatggtg
     1441 tattatcaat atcaaaacca aactcacgaa gatactgaat caaaaagacc gttactgtcc
     1501 gagtgtttcc ttcgcgaaat ggatgaatct gccagattcc tgaaataaaa tgctggattt
     1561 gtttaaccac atccgcctga gttagtgtcg catatgcaac ttgtttttcc tgattaaaat
     1621 cataatctaa ggtcatttga atcatggagt aatcagagta cacaacactt tcaccattca
     1681 aaacaggttc attctttgtg atattggtct gacgaaattg ccccaccgga atagagggtt
     1741 caaatatatc ttgaaacaac tccttatgaa tagcaagtaa ggtcgcagga ctaaagctaa
     1801 agcctcttcg agacaatagt tctacaatac gtagagaaac caagtctgcc tcttccgtac
     1861 ttgcatcaat agtatggtga taagccgttg catcctcata aacctgctca taagtcagtt
     1921 ctccccggga ctgtttctca gccaaagatt ccatatacgc tgatggcact agattgtcaa
     1981 ctttctgcag accaaaacct atccgccata aatcacgctt cgcttcataa gacaagtttg
     2041 gattgtcaat gttgtaagtt ggttgcatag aaatatcctt tcaattgttt ttcttcatta
     2101 ccagtaaatc acgaaattgg ttggaaactg gcttaaacta taaaaagtcc tcacaatagg
     2161 ttctatgata tatatatata tatatatact tcatgtaaat aataaaagag ttataatcag
     2221 cactactgat aaattcaata ccgatttcgc catcttaaaa cttagtcaaa cgaataccgt
     2281 tgatttccag ttcattaagt cgttgacctg tcaagacttc tcgttccttc aactggaaaa
     2341 gttaaggggg aactaataca aatcctctac gcttctatat tcaatgattt catttttgat
     2401 aatattcttt ttaaactcaa aatgttttaa aggattatcg attaacacta actttggaat
     2461 atcatctaga tttgtgacca aggataaaat aaaatccgat tgaaactcct tgactttttc
     2521 aaattctttt gcagttaaac gcacacgccc cttagatttt cggatacctt ttacttcggc
     2581 aaggtaagaa tactcttgga catctacctg aaagtcatat ccatcaccat aaagacgggc
     2641 atcggttaac tgtccacctt ggaatttttc ttctttatca aaatgaagga taaaataatt
     2701 ctcagcctcc attcccgttt cctgtagacg tttgaattta gttcgaacta ttggtttttc
     2761 aacgatggtt atgcctgttt tcttcccttc actggcaagt aacattttaa ctatttcagc
     2821 ataactatga acatcttcat ttccaaacat catatcaatt aaatctttac gaaaacgata
     2881 aacttcagct ttctgccacc aaccttttcg attattgtca aaataaggat caaataaatc
     2941 cattctattt tttacaactc cagttgtttc agcaattccc agagaaacca catagcgata
     3001 aaactccgac ttgctagagc attgaaattc ttttataaaa agcttgtcaa acttggcaag
     3061 accgtagcca attaaattta acaattcata atgagggtgt ttggacatca ctttctccat
     3121 caatagatat tgatttcatt ataccaaaaa acacggctca tcaccgtgtt tctgtgttta
     3181 tttcaccaac ttcttcatct catcaatacg tgctacggtc gcatcatact tggcttggta
     3241 gtcagcttgt ttgtcgcgtt ctttttggac gacttctggt ttggcgttgg ctacgaagcg
     3301 ttcgttagag agtttcttac cgaccatatc cagttctttt tgccatttag cgagttcctt
     3361 gtcgagacga gccagttctt cttcgacatt gagaaggtct gccagtggca agtagatttc
     3421 tgctcctgtg atgacgcttg acatagccag ttcaggtgca gggatggttg atgcgatttc
     3481 caaatgttct ggatttgtaa agcgcttgat gtagttgaca ttgctgttaa agaaggcttc
     3541 caagtcacta tcgctagtct taacaaggat tgtgataggt ttgcttggtg ctacatttac
     3601 ttccgcacgc gcattccgaa cagcacgaat caagtttttg agactttcca caccagtgtg
     3661 ggcagcaagg tcttcaaagg ctgggttgac agttgggtat gctgctgtca cgatagagcc
     3721 ttcagcgtac tgaccaaaga tttcttctgt cacgaacggc atgattgggt gaaggagacg
     3781 aaggatttta tccagcgtat agaggagaac agatcgagta attaccttat cgtcttcatt
     3841 gtcgctgtaa agaacttcct tggtcaactc aacataccag ttggcaaatt cttcccaaat
     3901 gaagttgtaa aggatatgac cagccacacc aaactcaaac ttatcaaagt tttcagtaac
     3961 ttttgcaatg gtttcgttga gattgtggag aatccagcgg tccgtcacat taccagcctc
     4021 acctgttgca acttttgtga cattgtcatg cgccacatcc agcgtcaaac ctccattgtt
     4081 catgaggata tagcgagaaa tgttccaaat cttgttaata aagttccatg aagcatccat
     4141 tttctcgtaa gagaaacgaa cgtcttgacc aggagctgag ccgtttgaca agaaccaacg
     4201 aagactatct gtaccatatt tatcaataac atccattggg tcaatgccat ttccaagaga
     4261 tttagacatc ttacgtcctt cttcatcacg aattagacca tggataagga cgttttggaa
     4321 tggttgacgg cctgtgaatt ccaatgactg gaagatcata cgagacaccc agaagaagat
     4381 gatgtcgtaa cctgttacca aggttgaagt tgggaaataa cgtttaaagt cttctgagtc
     4441 gacttcaggc cagcccatgg ttgaaaatgg ccagagggca gaactgaacc aagtatccaa
     4501 gacgtcttcg tcctgagtcc atccgtcacc ttctggagct tcttcgccga catacatttc
     4561 accatcagca ttgtaccagg cagggatttg gtgaccccac caaagctgac gagagataac
     4621 ccagtcgtgg acattttcca tccattgaag gaaggtatcg ttgaaacgag gtgggtagaa
     4681 ttcgaccttg tcctctgtgt cttggttggc aatggcgttc ttagccaatt ggtccatctt
     4741 gacgaaccat tgagtagaca agcgtggctc aactacgaca cctgtccgtt ctgagtgacc
     4801 gactgaatgg acacgttttt cgattttgac aagggcaccg atttcttcca acttagcaac
     4861 gactgcctta cgagcttcaa aacgatccat gcctgaaaat tcaaaggcaa gctcattcat
     4921 agttccgtcg tcgttcatga cgttgacttg tggcaagtta tgacgttggc caaccaagaa
     4981 gtcatttgga tcgtgggcag gtgtgatttt cacgacacca gtaccaaact caggatctgc
     5041 gtgctcatct ccaacgattg ggatgagttt attagcgatt ggaaggatga cgtttttacc
     5101 aatcaagtcc ttgtagcgcg ggtcttctgg attaaccgca accgcaacgt ccccaaacat
     5161 agtctcagga cgagttgtag caacttcaag ggcgcgtgaa ccatcttcca gcatgtagtt
     5221 catgtggtag aaggcacctt cgacatcctt gtgaatcacc tcaatatcag aaagggctgt
     5281 gcgagctgct gggtcccagt tgatgataaa ctcaccacgg tagatccagc ctttcttgta
     5341 aaggtccaca aagaccttac gaacagcttt tgacaaacct tcgtcaagag tgaaacgctc
     5401 acgagagtag tctacagaga gccccatctt gccccattgt tccttgatag tagtggcata
     5461 ttcgtctttc cattcccaga ctttcgtcaa gaaagactca cgaccaaggt catagcggga
     5521 aatgccctca ccacgcaagc gctcctctac cttagcctga gtggcaatcc ctgcgtggtc
     5581 catcccagga agccaaaggg tatcaaaacc ttgcatgcgt ttttgacgga tgataatatc
     5641 ttgcaaagtt gtatcccaag cgtgaccaag gtgaagttta cctgtaacgt ttggtggtgg
     5701 aataacgatt gaataaggct tagccttttg atcgcctgaa ggcttgaaaa catcagcatc
     5761 aagccatttt tggtaacgac cagcctcaac ctcggctgga ttgtatttag atgaaagttc
     5821 tttagacatg tgtgttctcc ttaattactt ttattgacaa ttttaaccaa accaattttt
     5881 gaaagttcaa tataaatctc ttcaatttca gcaaatgctg caagtggtga catagtataa
     5941 tttccaggat tatatttaag atcatacttg cttatctttg aaatataata cctagagtgt
     6001 ttcaatttta atgattcca
//
LOCUS       DAVKZI010000078         5995 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKZI010000078 DAVKZI010000000
VERSION     DAVKZI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.079"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..753)
                     /locus_tag="VXB18_002081"
     CDS             complement(<1..753)
                     /locus_tag="VXB18_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0383216.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLN"
     gene            complement(755..1312)
                     /locus_tag="VXB18_002082"
     CDS             complement(755..1312)
                     /locus_tag="VXB18_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0383217.1"
                     /translation="MARTELSDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIAGSVDFNHRYGDDVLELGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEE"
     gene            complement(1299..1748)
                     /locus_tag="VXB18_002083"
     CDS             complement(1299..1748)
                     /locus_tag="VXB18_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEV0383218.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQISILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPEFLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(2161..2556)
                     /locus_tag="VXB18_002084"
     CDS             complement(2161..2556)
                     /locus_tag="VXB18_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0383219.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(2652..2906)
                     /locus_tag="VXB18_002085"
     CDS             complement(2652..2906)
                     /locus_tag="VXB18_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0383220.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(2916..4250)
                     /locus_tag="VXB18_002086"
     CDS             complement(2916..4250)
                     /locus_tag="VXB18_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0383221.1"
                     /translation="MTDERIHVLRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(4250..4483)
                     /locus_tag="VXB18_002087"
     CDS             complement(4250..4483)
                     /locus_tag="VXB18_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0383222.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            4514..4591
                     /locus_tag="VXB18_002088"
                     /pseudo
     CDS             4514..4591
                     /locus_tag="VXB18_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4931..5113)
                     /locus_tag="VXB18_002089"
     CDS             complement(4931..5113)
                     /locus_tag="VXB18_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383223.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(5115..5894)
                     /locus_tag="VXB18_002090"
     CDS             complement(5115..5894)
                     /locus_tag="VXB18_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383224.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDSSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWVSREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT         1758 a         1354 c         1042 g         1841 t
ORIGIN      
        1 gtttaacttt aaaaacaact tattataatt accatagagc tctgtaagag cattaaagta
       61 ttctttcact agagctatag cgtcaatctt agatgtttct tggtttagtt ttatcaactc
      121 ccctttcaat tttttccatt taaagttgga atttaaaaga taatctaaat caatatagaa
      181 atctattata acagtctcat catctgggct aacagctttt acctcattta ttggtaagtc
      241 agtatgttgc gaataatttc tcaaagaatg gcaaaatcga taagtaaaat tgatatcata
      301 ctgatagctt gcaaaaccat gtatacaatc aaactcctca ctatctttgg aatatttttg
      361 tttaatttgg ttttcgttaa aatcgacaaa caattttcca ctggataata aatgaatcat
      421 gaaacgattt acatctgcct cttcaatttc taattccttt gactcaagtt tatttttaat
      481 acttaaaaaa tccgagacat ctgaaataaa caattcgaac atattcttga ttttttgaaa
      541 attcttttga atctcaaaaa tttggtccga gactgacatt atttccttgg ttggttcaat
      601 atcagagatg acaatacgtt tttcattgtt gttaatttct aaataagcta atcgctcgat
      661 aatatcacta tcatttaatt cagcatactc aacatcaatt tggcgtaact gcttctcaga
      721 tagagagctt acttcctctt ttacatcgct catcttattc ctcccattca ctcttcagca
      781 aggcatatct taaatcatca cagcagttgc cttgagcatc tttgcggtct cttatgcgag
      841 cttcgagggt aaagccaagc ttttccgcga ctcgtttact ttgaaggtta tatccaaagc
      901 aagttagttc aatcttgtga agacccaaat ctttaaaggc taagtcaatc aaggcacgcg
      961 cagcttctgg aacataacct cgaccccagt agtctgagtg taaggtatag ccaagctcta
     1021 gcacatcgtc cccatagcga tggttgaaat cgacagagcc agcgatctta tccgttcctt
     1081 tgacgacaat cccgtagcct gctgggagat tttccttttg attacgctcc ggaagaatgt
     1141 gctccagata ataaatctca tcttccaagg tcttgactgg aggaaaacct gctggatagg
     1201 cgacctctgg caaactagcg taggcatgga tatcctcagc atccgccaca gtacggactc
     1261 gtaaaacgag acgttctgtt tcgattttat ctgacagctc agttcttgcc atccttcttc
     1321 ctcgcttttt tgatgaaact gcccttcata tctacacgct tgtccagata gcgataaacg
     1381 cgctgatatc catctcccat gaaataggtt ggggcaaaca gttgattttt aaaatgtccc
     1441 ttttcatcca ggaattctgg ggcaacaagt cgctcaagaa tcttggcaaa gatgtggcaa
     1501 ataccgtctt cctcaacaat cctatctacc cgacaatcta aaacaagtgg acaggcgtct
     1561 aaaatagaaa tctgagttcg ttcagaaatt tcataatgca ctcccaaacg ttccaatttc
     1621 tcctgatgac tgataaaacc agcctgctcc atcgcaagca tagaagtttc atcagaaata
     1681 ttcacagtaa atttttgata ctgtttgatc tgctctgcgg cattctctct cgcaacgact
     1741 ccaatcacaa cccaatctcc tagactataa gaggaactac aggtcgtgat gttatagcca
     1801 aaattctaat cttgatatcc taaaataaaa acaggaaaac cataatatag tttacttgtg
     1861 ttaaaagatt gcttcataac aacccccttt gactaagacg taaaagaaaa gccctgccat
     1921 ctacatgaca gggacgaatg tgtttatccg cggtaccacc caatttcggg cagttgcccg
     1981 caactctcgt ctttaaagca aaaagacact tttatttcaa tttttcatcc attagcaacc
     2041 agttttgaca catttgtgga cttctcagcg ccgccacttt ctgtaaaatg tgggattcaa
     2101 aacacctcta atggctctat tgtagcaaga ttttttcgga aatgcaaggc tcaagaaaaa
     2161 ttacttgaac ttgatgccat tttctttcaa tttcttgatg gtagctgggc cgattccttt
     2221 caaggcaagg agttcttttt cagtccagtt tttgaaatct gaagcagact tgattccttc
     2281 atcatagaaa gtcttggcac gatcaagtgg aagtccaccc aaatttgctg caaaatcttc
     2341 tacagaatta gctacttttt gagcttgctc tttggtagct tctactgctt gttcaacttt
     2401 tttagaaaca gccttaccag ctgcgcttgc tgactgttct gcacgcttca cgactttttt
     2461 tgtctcatct acaaccttag tcacagtact tgaaaaggca cctgcgcgac ggaggccatt
     2521 tcgtaattgt tttttacgat tgagtttctt tgacatgata aaatcctttc aataaaaaat
     2581 ccctgctctg acaaggattt aacataaaca ttctatcaag attttagtga aaaatcaaga
     2641 atctttctcg tttaataatt tcgctcacca aacaagcctt ctggcaaatc atggaatccc
     2701 ttgcctactt tgaagttttc aaacttacca agcaagaact gataagcatc caagcgactc
     2761 tcgtagcgaa tcatggcatc tttggcacgc tcgtcctggt cttcttcgta aactttttgg
     2821 ctttccttgt gcgccatgtc gttaatcatg atttgggtat tgacccaagc ttcaaattcc
     2881 ttcataaatt cttgttcgta actcattttt tctccttatt ctaatccacg gaaatagtcc
     2941 gtatcaatct cacggtaggg ctggatatcc tgaacgtatt ccagtacacc ttggaattct
     3001 ccgttttcat cgtgtactgc agcataggtg atgtggacaa actttcctcg cgactcagac
     3061 ttgaaccaca tttcatactt gtccttggtc ccctcacgaa gtcccttcat gatagccttg
     3121 accttgtcca aatacttagg cggatgacag agttcgacat tgcgcccgac ttgggacggc
     3181 gtccgtttga aaatcatctc atcagctggc gtattgtcat tgtaatactg gaaaatatct
     3241 tctttattga caaaggtaat ctccataggg agatgattga ggatgagatt ggcctgctcg
     3301 actgaaagat agccattacc aaaagcctgt tgactatggc ggtccagcac agcttccttt
     3361 tccttagggg taaaggtaat ggtaaaatgg ccttctggcg tatctatgac ttgttgaact
     3421 tgaccttctg ccgtatctag ctgtacaggc tcctctgcaa tcttttcctc aataaagatc
     3481 tgtcgttctg gcacccattt ctctgacgga cggatgatgg catagccata ggcatcactc
     3541 tcctccgcaa tctgaagcca gtcatcctga gtaaaagact caaggagaat catgagcagg
     3601 atggactctt ccttgaaaat catactttca aactctgtcg caaaagcttc aaaagcttcc
     3661 tttacactgc taattgacac ttctggtagt gacttggctg tcgttagagc tgtttgaaag
     3721 agttccctaa tctgatcatc cactccccac ataactttgg gaggtgaatc gtgtccatag
     3781 cgctccatga taggaaagaa gagttcttcc ttacgttggt aatggatgtc aaattgaccc
     3841 acaagtccca tctgacgcac caaaccctta cgcatctccg ccagcatttc ctcgtcttcc
     3901 atagactcat aggtatctaa caatctacga atgcgaatca aggccgcacg gagagccaga
     3961 ttttcttctt tgaagacacg aactgggtga cctggatgct cagtatctga aacttcgaca
     4021 cctttgatag catttttaaa aagattggca tggacatcac agagttccat aacatcttca
     4081 aaagtgacgc ccgaatccga gttcatcagc tcgtgctcca taagggaaat ctcgatggct
     4141 gacacgcccg taaaggtcgc atcaaagcga tcttgaaccg actcaggaga ggcgccattg
     4201 tgcaattcta acaaaatatc ccgtaggaca tgaatccgtt catctgtcat tagtctaatc
     4261 caatcacttc gtagccattc gcttccagtg tgcgtacaat cttgtccata ggagttcctg
     4321 ctagcttaga accctgttta agtgatactt tacgaccaac tgtattgcgc attaagggat
     4381 tggcaagggg tttaaaaccc aactccacta gaatttccaa gacttctgga tgcttgtcca
     4441 ccacttctgc aacaggaatt gacacatcga tgatattgtc catgacgacc tccattgtat
     4501 gttctaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgcttaaa
     4561 acagtgtttt gaggttgtgg atagaactga cgaagtcagc tcaaaacacc gttttgaggt
     4621 tgtggataga actgacgaag tcagtaacat atatactgca aggtgaagct gacgtggttt
     4681 gaagagattt tcgaagagta taaaatgatt ttactgctta tattatacca tatggagaga
     4741 gattaaaaaa ctagcagtgg ggttcctgct agttttctgc gacttggatt accatctaga
     4801 taagtttaaa gaaccaatcc aatatcttgt aaaacagcaa ttgaactgca aaagaaatga
     4861 tcatccaaaa gaatttcaca atcccaataa tcggtttgat aaaaagaata gcaagaagac
     4921 caaaaaaatt tcattctctc tcctctggct taatgagcca ccgagccgta tccattagct
     4981 tatctgcaat aaaaagtttg cccagaccaa caacgacatg gtcagctttc tttatcgttt
     5041 tcatcacttt tacaccttgc acggtcaaaa agtaattacc ataaatttta gctagagttt
     5101 ttatgagtcc catattactc tccttcgatg atttcagcct cttttcggat tgtttcaaca
     5161 tcttcttgat attgaacttc actatagttg actagcttgg ataattcttt ctgcaagctt
     5221 tcccccattg gtttcatagt tgcaaaggtt aaaccacctg aaatgatacc acccaagata
     5281 ggaataaatt tccccattcc tttggccaac cctcccttgg taagattcac accaaatatt
     5341 tttaagactt ttttcaaaat agggtaccaa agcgtctttg ttaaagcttt attaggcact
     5401 gttttcatta cctgtttggc aattgttata ccaccagcac gtagcaaagc agcagttcca
     5461 ttcaccccta acattacgcc tagataaagc aagagggtat tttgagcatc ttcactcaac
     5521 tcctctcgtg aaacccaaag atcctcataa ccataaatat aacctaattc ttgagccaat
     5581 ttcagagaga aagcataaaa ttgagccaca tcagctggaa tggtaattgc catagcaagc
     5641 cctccaggta atcctgccaa aacagaagtc ccactcgcta ataatacatt gtcccgaata
     5701 caagcattag ctactcgatc taagatttct tgagataaga gagacgttgg accttgttcc
     5761 aataaggtag gaatgtcctg tggacccaat tctttggaaa acttatccac taaaaatttc
     5821 gaactatcaa ccttaacaac tggtagtttt accacttgtt gtaatacttg catagctaag
     5881 tcttgttcag ccatatacaa actccttatt tcttttttac accttatcat attatatttc
     5941 ctacaaaaaa agcattttct aattagataa cattaaaaaa tacagaaccc ctttt
//
LOCUS       DAVKZI010000079         5867 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKZI010000079 DAVKZI010000000
VERSION     DAVKZI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.080"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            100..579
                     /locus_tag="VXB18_002091"
     CDS             100..579
                     /locus_tag="VXB18_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0383225.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            673..744
                     /locus_tag="VXB18_002092"
     tRNA            673..744
                     /locus_tag="VXB18_002092"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:706..708,aa:Glu,seq:ttc)
     gene            997..2542
                     /locus_tag="VXB18_002093"
     rRNA            997..2542
                     /locus_tag="VXB18_002093"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2594..2666
                     /locus_tag="VXB18_002094"
     tRNA            2594..2666
                     /locus_tag="VXB18_002094"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2627..2629,aa:Ala,seq:tgc)
     gene            2791..5692
                     /locus_tag="VXB18_002095"
     rRNA            2791..5692
                     /locus_tag="VXB18_002095"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5769..>5867
                     /gene="rrf"
                     /locus_tag="VXB18_002096"
     rRNA            5769..>5867
                     /gene="rrf"
                     /locus_tag="VXB18_002096"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1732 a         1136 c         1669 g         1330 t
ORIGIN      
        1 tcttttttgt acagtttagg agctaaaggg aacagaatgg ataaaatgga acaaatgtgt
       61 tttctaatct gttagactgt atctagaaag gggaaaatta tgattaaaga attgtatgaa
      121 gaagtccaag ggactgtgta taagtgtaga aatgaatatt accttcattt atgggaattg
      181 tcggattggg accaagaagg catgctctgc ttacatgaat tgattagtag agaagaagga
      241 ctggcagacg atattccacg tttaaggaaa tatttcaaaa ccaagtttcg aaatcgaatt
      301 ttagactata tccgtaagca ggaaagtcag aagcgtagat acgataaaga accctatgaa
      361 gaagtgggtg agatcagtca tcgtataagt gagggaggtc tctggctaga tgattattat
      421 ctctttcatg aaacactaag agattataga aacaaacaaa gtaaagagaa acaagaagaa
      481 ctagaacgcg tcttaagcaa tgaacgattt cgagggcgtc aaagagtatt aagagactta
      541 cgcattgtgt ttaaggagtt tactatccgt acccactagt aagtcatgca aaaaaaatga
      601 aaaaaattag aaaaagtagt tgacaaagtt tgaaaagact gtataatagt aagagttgaa
      661 aataacaact caggtccgtt ggtcaagggg ttaagacacc gccttttcac ggcggtaaca
      721 cgggttcgaa tcccgtacgg actatggtat gttgcgtcag gaccacttga tgaaaaaaag
      781 tttaaaaaaa cttaaaaatc ttcaaaaaag tgttgacaag tgaaagtggc tgtgatatac
      841 taatatagtt gtcgcttgag agaagcaagt gacaaagacc tttgaaaact gaacaagacg
      901 aaccaatgtg cagggcgcta caacataagt tgtagtactg aacaatgaaa aaaacaataa
      961 atctgtcagt gacagaaatg agtgagaact caaactttta atgagagttt gatcctggct
     1021 caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag gaggagcttg
     1081 cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct ggtagcgggg
     1141 gataactatt ggaaacgata gctaataccg cataagagta gatgttgcat gacatttgct
     1201 taaaaggtgc acttgcatca ctaccagatg gacctgcgtt gtattagcta gttggtgggg
     1261 taagggctca ccaaggcgac gatacatagc cgacctgaga gggtgatcgg ccacactggg
     1321 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggacg
     1381 gaagtctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
     1441 gtaagagaag aacgagtgtg agagtggaaa gttcacactg tgacggtatc ttaccagaaa
     1501 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
     1561 tttattgggc gtaaagcgag cgcaggcggt tagataagtc tgaagttaaa ggctgtggct
     1621 taaccatagt aggctttgga aactgtttaa cttgagtgca agaggggaga gtggaattcc
     1681 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
     1741 ggcttgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
     1801 tagtccacgc tgtaaacgat gagtgctagg tgttagaccc tttccggggt ttagtgccgt
     1861 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1921 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1981 cttaccaggt cttgacatcc ctctgaccgc tctagagata gagttttcct tcgggacaga
     2041 ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     2101 caacgagcgc aacccctatt gttagttgcc atcatttagt tgggcactct agcgagactg
     2161 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     2221 ggctacacac gtgctacaat ggctggtaca acgagtcgca agccgatgac ggcaagctaa
     2281 tctcttaaag ccagtctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     2341 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     2401 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg taaggagcca
     2461 gccgcctaag gtgggataga tgattggggt gaagtcgtaa caaggtagcc gtatcggaag
     2521 gtgcggctgg atcacctcct ttctaaggat aaggaactgc gcattggtct tgtttagtct
     2581 tgagaggtct tgtggggcct tagctcagct gggagagcgc ctgctttgca cgcaggaggt
     2641 cagcggttcg atcccgctag gctccattgg tgagagatca ccaagtaatg cacattgaaa
     2701 attgaatatc tatatcaaat agtaacaaga aaataaaccg aaaacgctgt agtattaata
     2761 agagtttatg actgaaaggt cagaaaataa ggttaagtta ataagggcgc acggtggatg
     2821 ccttggcact aggagccgac gaaggacgtg acaaacgacg atatgccttg ggtagctgta
     2881 agtaagcgat gatccaggga tttccgaatg ggggaaccca acaggtaata cctgttaccc
     2941 acatctgtta aggatgtgag gaggaagacg cagtgaactg aaacatctaa gtagctgcag
     3001 gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga agggcaaacc
     3061 gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt atagaagaat
     3121 gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt ctttgtacct
     3181 agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg aggaccattt
     3241 cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg gaaaggtgaa
     3301 aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa caagttcgag
     3361 cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac gttatgatgc
     3421 gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg cgccttagta
     3481 tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg tgcggtaaga
     3541 cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg tgggtagcgg
     3601 agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt agggctagcg
     3661 tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca tcccggatta
     3721 ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga ctgcgagtgc
     3781 taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaataattg
     3841 ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta gaagcagcta
     3901 ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga aaatgtaccg
     3961 gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg agagcgttct
     4021 atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag aatgccggta
     4081 tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt ccaggggaag
     4141 gctcgtccgc cctgggttag tcgggaccta aggagagacc gaaaggtgta tccgatggac
     4201 aacaggttga tattcctgta ctagagtatg tagtgatgga gggacgcagt aggctaacta
     4261 aagcagacga ttggaagagt ctgtctaagc agtgaggtgt gaattgagtc aaatgcttaa
     4321 ttctataaca ttgagctgtg atggggagcg aagtttagta gcgaagttag tgacgtcaca
     4381 ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa ccgacacagg
     4441 tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac tcggcaaaat
     4501 gaccccgtaa cttcgggaga aggggtgctg actttaagtc agccgcagtg aataggccca
     4561 agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt atagggggtg
     4621 acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag gtatgaattg
     4681 aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa ttccttgtcg
     4741 ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc actgtctcaa cgagagactc
     4801 ggtgaaattt tagtacctgt gaagatgcag gttacccgcg acaggacgga aagaccccat
     4861 ggagctttac tgcagtttga tattgagtgt ctgtaccaca tgtacaggat aggtaggagt
     4921 ctaagagatc gggacgccag tttcgaagga gacgctgttg ggatactacc cttgtgttat
     4981 ggccactcta acccagatag gtgatcccta tcggagacag tgtctgacgg gcagtttgac
     5041 tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa ggttccctca gaatggttgg
     5101 aaatcattcg cagagtgtaa aggtataagg gagcttgact gcgagagcta caactcgagc
     5161 agggacgaaa gtcgggctta gtgatccggt ggttccgtat ggaagggcca tcgctcaacg
     5221 gataaaagct accctgggga taacaggctt atctccccca agagttcaca tcgacgggga
     5281 ggtttggcac ctcgatgtcg gctcgtcgca tcctggggct gtagtcggtc ccaagggttg
     5341 ggctgttcgc ccattaaagc ggcacgcgag ctgggttcag aacgtcgtga gacagttcgg
     5401 tccctatccg tcgcgggcgt aggaaatttg agaggatctg ctcctagtac gagaggacca
     5461 gagtggactt accgctggtg taccagttgt cttgccaaag gcatcgctgg gtagctatgt
     5521 agggaaggga taaacgctga aagcatctaa gtgtgaaacc cacctcaaga tgagatttcc
     5581 catgattata tatcagtaag agccctgaga gatgatcagg tagataggtt agaagtggaa
     5641 gtgtggcgac acatgtagcg gactaatact aatagctcga ggacttatcc aaagtaactg
     5701 agaatatgaa agcgaacggt tttcttaaat tgaatagata ttcaattttg agtaggtatt
     5761 actcagagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagaag
     5821 ttaagcccta gaacgccgga agtagttggg ggttgccccc tgtgaga
//
LOCUS       DAVKZI010000080         5847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKZI010000080 DAVKZI010000000
VERSION     DAVKZI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.081"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(177..248)
                     /locus_tag="VXB18_002097"
     tRNA            complement(177..248)
                     /locus_tag="VXB18_002097"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(213..215),aa:Arg,seq:cct)
     gene            complement(291..638)
                     /gene="rplS"
                     /locus_tag="VXB18_002098"
     CDS             complement(291..638)
                     /gene="rplS"
                     /locus_tag="VXB18_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0383226.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(757..1086)
                     /gene="crcB"
                     /locus_tag="VXB18_002099"
     CDS             complement(757..1086)
                     /gene="crcB"
                     /locus_tag="VXB18_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0383227.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1080..1454)
                     /gene="crcB"
                     /locus_tag="VXB18_002100"
     CDS             complement(1080..1454)
                     /gene="crcB"
                     /locus_tag="VXB18_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0383228.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1451..1717)
                     /locus_tag="VXB18_002101"
     CDS             complement(1451..1717)
                     /locus_tag="VXB18_002101"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0383229.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(1833..2276)
                     /locus_tag="VXB18_002102"
     CDS             complement(1833..2276)
                     /locus_tag="VXB18_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0383230.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2380..3315
                     /locus_tag="VXB18_002103"
     CDS             2380..3315
                     /locus_tag="VXB18_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0383231.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3369..3653
                     /locus_tag="VXB18_002104"
     CDS             3369..3653
                     /locus_tag="VXB18_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0383232.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3710..4288)
                     /locus_tag="VXB18_002105"
     CDS             complement(3710..4288)
                     /locus_tag="VXB18_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV0383233.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(4263..5276)
                     /gene="efeB"
                     /locus_tag="VXB18_002106"
                     /pseudo
     CDS             complement(4263..5276)
                     /gene="efeB"
                     /locus_tag="VXB18_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909774.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(5279..5830)
                     /locus_tag="VXB18_002107"
                     /pseudo
     CDS             complement(5279..5830)
                     /locus_tag="VXB18_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         1791 a         1303 c         1043 g         1710 t
ORIGIN      
        1 aataaattga ctatacaaac atttatatac tcgatatagt ctcaatttta tctgataatt
       61 gcccaaattt ttcaataata aaacgcataa tattatggag acacacaaaa tcacctatat
      121 tatgcgttct tttaatatca aagacttttt gacaaacttc tttgatgtct aattactgcc
      181 ccctgcagga atcgaacctg caactactcc ttaggaggga gttgttatat ccattgaact
      241 aagggagcta gataaaaact ctgctaaatg agcagagttt tttagtcgaa ttaacgacgg
      301 atttctttga tacgagctgc tttaccttga agagcacgca agtagtacaa tttcgcacga
      361 cgtactttac cgtaacgaac aacttcgatt ttttcaacac gtggagtgtg gattgggaag
      421 atacgctcaa cacctacacc gttagagatt ttacgaactg tgtagttttc tgagattcca
      481 gcacctttac gtgcgataac aacaccttca aaaatctgga tacgttcacg gttaccttcg
      541 acaactttcg catgtacacg aacagtgtca ccaggacgga atgatgggat atctgtacga
      601 agttgacctt cagtcaagct ttggattaat ggattcattt tattctccta tctttgtcaa
      661 tcttgaggaa tcttcctcag cggataaact gtatttttgt gcgtccatta cacacaagat
      721 atagtttacc aaatttctaa aaaaaagtaa agaaatttat agcaaaattc ctaaaaaaat
      781 cgcaaccaaa ccacctatgt aagtcaaagt caggtaagaa taaaagacct tcttatcact
      841 tagcagtctt tgaagttcgt cattcaaggt cgaaaaagtt gttaaaccgc cacaaaatcc
      901 tgttgctaga atagcatata cttccttaga ctctacatga ttgtagaata ctccaattaa
      961 aaaacaacct aaaagattag ctatgagcgt tccaagtggc aatttagaag cttgattgta
     1021 gcgggaaaag aaataccgta cgagtgctcc gaaaccacaa gcaattgcaa gatagacgat
     1081 taccatttct tcctccctag aaaataagct aagagtaggc ctccaccgat gctcaaaagc
     1141 aaatacagga ctaaactaag ataacgccct gtatcaagca gcttcacagt atcaagcatt
     1201 aggctggaaa aagttgttaa acctccgcaa aaacccgtcc ccagtgctaa aatcaagccc
     1261 ttactagtcc ccttatagac cagatagccc ttgacaagaa aaatcaagca gaaaattccc
     1321 agatagttga caaagagagt gccccaagga aagtctggac tggctggtaa ccaggtggaa
     1381 actagatatc ggacaagtcc gcccaacata gcagctagaa aaattcctag cggataaaat
     1441 tgttcttttt tcatttgata ttttgatcct gataatcacg cgaacgtttg agtatgtccg
     1501 aaaaagtcgc gacaatagtc tcctgatagc gcttgtcctc tacacgactc ctaacctttt
     1561 caaaaataac ttcttctctc ttagtatcta aaatcggttt acctgaagct ttcttataag
     1621 caaccacccc ctcaactaaa tgcattcgtt cttctaacag tttgacaatt tggtcgtcga
     1681 tttgatcgat ttcttgacga ataatatcta aatccataca gtctcctcct ttatttgaat
     1741 tattgtatca aaaagccatc aattaggcta gtaaaatccc aactctcgat aagaaaaatg
     1801 cactgattga ttacatcagc gcacttttat gtttatccta ctttagcagc caattcttct
     1861 gcgaattgtt ccaagcgttc aatatcttct tcctcggcag aaagatcaac tttaacacac
     1921 tctgaacctt tttctgctcc tgttgacaca aagacacggt caaagtcatc aacagcctta
     1981 cagaattcat cgtagaaggt atctcctgag ccgaccactc cgtagatttt gccattcaag
     2041 ttgagatctg ctaggtcttc gtagaagtcc atcatctcat ctggcaattc accatcacca
     2101 taagtatagg tcgcaacgat agcgatgtct gcttccaaga agtctgaagc gtcaacagtt
     2161 gtacattcat caacatcaac atccaagccc aagtcacgta atttgtctgc tacaatatct
     2221 gcaatttctt cggtattacc ggtcatactg gcaaatacaa tttttgctaa tgccatatcg
     2281 tcctcctcaa tttatctttc tccattatat cacatctttt tcattttaaa aataaaaatt
     2341 cttgtgctac aatgaaatga gaaagaattg aggttattta tggagatttg ccaacaaatt
     2401 ttagaaaaaa ttaaagaata cgacaccatt atcattcatc gtcatatgaa accagaccct
     2461 gatgccttgg gaagtcaggt gggattgaaa gccttgctgg aacatcattt cccagaaaaa
     2521 accatcaaag ccgtcggttt tgatgaacca actcttactt ggatggctga gatggatctt
     2581 gttgaagata gagcctacca aggcgcactt gtcatcgtct gtgatacagc taatactgct
     2641 cgtatcgatg ataagcgcta tagtcaaggt gattttctca ttaagattga ccaccatcca
     2701 aatgatgatg tatacggtga cctgtcttgg gtcgatacta gttcaagtag cgctagcgag
     2761 atgattaccc tatttgccca aacaacccaa ctagccttgg cagatcgcga tgctgagttg
     2821 ctctttgcag gaattgtcgg tgatacaggt cgcttcctct acccttctac cactgcacgg
     2881 actcttcgcc tggctgctta tttgagagaa cataactttg actttgcggc tctcactcgc
     2941 aaaatggaca ctatgagcta caaaattgct aaactgcaag gctacatcta cgaccatctg
     3001 gaagtggatg aaaatggtgc tgctcgcgtt atcctgagtc aagaagtctt gaaacaatac
     3061 aatgtaaccg atgctgaaac tgcagccatt gtcggtgcac ctggacgcat tgacagagtg
     3121 agtctctggg gaatttttgt cgaacaggct gatggccact accgcgttcg cttacgcagt
     3181 aaaatccatc ctatcaatga aatcgccaag gagcatgatg gtggaggcca ccctctagca
     3241 agtggtgcta attcctatag cctagaagaa aacgaaatca tctaccaaaa gttaaaaaac
     3301 ttgcttaaaa actgataaaa tacttgccaa acttttcaga atctgataga ctagtatggt
     3361 aacaatctat ggctcgcaaa gagaccatgg cagaaaggaa atattgcaaa atgaaaaaag
     3421 atatccatcc agaatatcgc ccagttgtct tcatggatac aactactggt taccaattcc
     3481 ttagcggttc aacaaaacgc tctaacgaaa cagttgagtt cgaaggcgaa acttacccat
     3541 tgatccgtgt ggaaatttca tcagactcac acccattcta cactggacgt caaaagttca
     3601 ctcaagcaga tggacgcgtg gatcgtttca acaaaaaata cggtctcaaa taatgataag
     3661 agaacagttt cggctgttct tttttgtttc ttgaaatcaa ctgctgtttt catgttccag
     3721 actcatctgt aggttcggtt tccatgctac taggcaggaa ggaaatagct gtttcaacac
     3781 gtccataatg agctgtacta ttgtcacgaa ccacactttc attgatggtc caagtggaat
     3841 tcattttctt aaaagcttct cggacttttt ccaaatcttt ggaggcaatg gcctgttcta
     3901 aggtttcaaa acgaggactt agacggttta ccaatttttc cttttccgca tctaggtcaa
     3961 caggattttg ttctttttca aaagctaata gagctgagga aatttcggtg agtttggctt
     4021 cagtaatatc tccagataga gctaactttt ccttaacaat cttaccaacc tcagaatcct
     4081 tattttctac tctttcgaag tctgatgcca tcttcgtaac gagtttctgg gtctcagtct
     4141 gaccaccatt tttaaccgtt ttggatgcat ctgtgatttt cacaaagaaa aaactcaagc
     4201 tttcttgggc acctgctggg gaaagaatta aaaatgacaa agctaaaact agtaaccagc
     4261 ttttagcctt ccaataattt ctgaccaatg tagcctcctt tctccacacc accaaagcaa
     4321 gtaaaaagtc cactacctat gtgagtgatg tattcattca tcttatcagt agcacctagg
     4381 ttagtttgaa ccttaacaaa gttatcagga tccttctgga aagaaatgaa gagcaatccc
     4441 gtatcaaact gaccagtctt ttcatcaatg ccatctgagt aagaataaga acgacgtaaa
     4501 agtggcttat ccacttcttt ggccaaacaa acatgcgaat catcaggtaa gagactcaaa
     4561 tccacttcat caaactcatt tttcttacca aagggggcac cgctttcctt gtaacgacca
     4621 aaggtatttt cttgttcttc gagactagtg cggtcccagg tctctaaaaa catctgaatc
     4681 cgacgaactg ccatataaga accattttcc atccagtcct tactatcagc ccagataacg
     4741 cggtcaaagt cttgctcctt ggttggattt gctgttccat ccttaaaacc aaagaggttc
     4801 cacggagtct ccattcgatc cccgatagct gcaaatccag actgactcca acgaaggggc
     4861 accgcatttc tccccttacg gatgagattg cgaatagcgt gaaaggcaat ttgctcatca
     4921 tctgcacaag catgaatcac aatatctcca ccagtatatt tttcacgtaa ttgctcctta
     4981 ggaaatagag gtaaatccct gaacagtcga gggcgcttgt tttccaagtt catccttttc
     5041 aagaaacttg cagatacacc aaaagtcagc gtcaaacgat gaggattgag cccaactgtc
     5101 tcaccagtat cgctcggagg aaagagagca ttctgtccat cttttttaac caattccccc
     5161 tcgaccaact tggcactata atccgtccaa tccttgaata gctggataat tttatctcta
     5221 tccgtcgtat gcaggtccaa gacaacaaaa tagatattct tttgcatggg cgtactattt
     5281 ggtacatcaa gcgaacctta tgaaaacgtc tactatattt aaaacgcttt cttgtcttct
     5341 tgaattgaga ttttattttt agacgcgaca atggtttgag cgtctgcttt cttaggatgt
     5401 tctggacgtg gcataatatt tcgccaacca tggcgcttca acagttgata gaaggcatca
     5461 cgtgtgtagg aacgacctaa ctccttttta taagcctgaa ataaggcatc aattgtaaca
     5521 aattctcctg cctctgcagc cttcaaatgg cgggcaagaa agactttctt ttcctcaact
     5581 gtcatatatg catggttacg accactacgt gtttcttgaa ggagagagtc gagtccgaac
     5641 tcctcatatt tttttacatt ttgctaaatc gttgtttgat tacagtctaa aagctctata
     5701 atctctttat aagatttgcc catcagacga aatataataa attgaaacta gaatagtaca
     5761 cctctacttc taaaacattg ttagaaatcg atttgactgt cctaatcgat ttgtcctgtt
     5821 cttgtttcat tttactatag aacgatt
//
LOCUS       DAVKZI010000081         5564 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKZI010000081 DAVKZI010000000
VERSION     DAVKZI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5564
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.082"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            96..929
                     /locus_tag="VXB18_002108"
     CDS             96..929
                     /locus_tag="VXB18_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEV0383234.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLGKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     K"
     gene            955..2016
                     /locus_tag="VXB18_002109"
     CDS             955..2016
                     /locus_tag="VXB18_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0383235.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            2033..3037
                     /locus_tag="VXB18_002110"
     CDS             2033..3037
                     /locus_tag="VXB18_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383236.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            3049..4743
                     /locus_tag="VXB18_002111"
     CDS             3049..4743
                     /locus_tag="VXB18_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0383237.1"
                     /translation="MRKSLNWKDWLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFHPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4745..5446
                     /locus_tag="VXB18_002112"
     CDS             4745..5446
                     /locus_tag="VXB18_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0383238.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
BASE COUNT         1926 a          758 c         1014 g         1866 t
ORIGIN      
        1 attttaaaaa ataatgaaac gttccaactt atctattgac acgttccaag aaatcggata
       61 caatgtaatt aacaataaag ataggagaaa ataatttgaa tccattaaaa gaatgctatg
      121 aaaaaaacgg tatactaatt gcagcacacc gtggtacaaa cggaggaaat atattacaaa
      181 acacatcaaa agcctatttg aattccatac gccataacgc agatatgttt gaggttgatg
      241 taattcgttc aaaagatgga gaattttttg catttcacga tgggcaagaa cctttagtat
      301 ttggtgaaaa aattgatatt agaactttga gttctgaaga gatccaaaga aaggaatgtt
      361 ttaattcact gaatgaaccc atattacaaa agattgaaaa aatttctgat gtattaaaaa
      421 attttgaggg acagtcttta ataaatatag atagaagttg gttttactgg gataccttcc
      481 taggtaagtt aaaaacatat ccatctttga atcaagttct tttaaaatca cctgtaaaaa
      541 aagaattatt ggaaatgctt agagactctg gtttgaatgt tatgtatatg ccaattatca
      601 aaacaattga agagttagat tttgttcttt catttgaagg aataaataca gtagctgtcg
      661 aacttgtatt ccaagattta gaaaatccaa tcataagtaa gaaagtaatt gatgatttac
      721 atgaaaaagg attacttatt tgggttaatg ctttaacctt aagtgattca attattcttt
      781 cggctaagat tgatgatgat acagctattg ctcatgatgg cgaatcttgg gggaaattgg
      841 tttcaatagg atttgatatt attcaaacag attggccatt attactttat caatatctag
      901 ttgaaaaaaa taaaaaaata aaaaaataaa aaataataat aaaggagaac tatcatgttc
      961 aaaaacttta aaaagattgc attcacttct tcactaattt tacttgctgc ttgctcaaac
     1021 aatgcttcaa atacaaatca gtctactgat gaaggaagtg ttgataaatc tcaagaaatt
     1081 gtaatctata caaattcggc ttctaatgga cgtgcagatt ggttacaaac caaagcatca
     1141 gagcaaggat acaatcttcg tttggtagat atttcaggtg gagaactagc tgaccgtttg
     1201 attgcagaaa agaataatgc tgtggctgat atggtaattg gattaaataa attagaattt
     1261 aaccgtatta aagctgaaaa acttcttgta aaatactcac caaaatgggc tgatgaagta
     1321 gatagctctt tgggagattc tgaagggtat tattcaccaa ttgtaaatca accattagtt
     1381 ttgattggta ataaagatgc taaaatgcca tccgactgga cagattttac tgattcatct
     1441 tataaaggta aatatggtat ttcaaaatta agtacaggta catctaagaa catctttgca
     1501 agtattgttt cgagatataa agatgaaaaa ggtgagttag gaatatctga tgaaggttgg
     1561 aaagttgcaa aagcttacct taaaaatgca cacgtttatg cagaaggtga agactatatc
     1621 tcttcaatta tggataataa taatgagcta aaatatagta tgatgtgggg atctggtgtt
     1681 ctacaaaatc aaaaagaacg tgaatataaa ttccaagtaa tgtcaccaaa agttggtgtt
     1741 ccttatgtaa ctgaacaagt tgggatttta aatacaagta agaagcaagc attattaaaa
     1801 gaatttgtag attggtttgg ctcttcagaa cttcaaaaag aatggtctga taaatttggt
     1861 tcaattccag ctaataaaaa agctctagag caagcaaaag atgaactcaa acagtttgct
     1921 aatagtgtta aaccacaaga acttgactgg gagtttatcg gaaaaaacat cgattcttgg
     1981 attgaaaaag cacagcttga atttgttgaa cagtaatagt taggattaag tgatgattac
     2041 atttaaggat attcaaatta agtataatga ttttattgcc atcgataatc tcaatttaac
     2101 aatcaatgaa ggagagtttt tcacattttt aggaccaagt ggttgtggga aatcaacaac
     2161 tcttcgtgca ctagttggat ttttggagcc ttcacagggg caaatactag ttgataatca
     2221 agatattacg aatttagatc cggaaaaacg cgaaattggt attgtgtttc aaagttatgc
     2281 attattccca acaatgactg tttttgataa tattgctttt ggtctaaaag ttaaaaaagt
     2341 ttctcctgaa attattaaag ctaaagttca tgaaattgcg aaaaaaatta atatctcaga
     2401 cgagcaacta aaccgaaata tttctgaatt atcaggggga caacaacagc gtgtagcttt
     2461 agcacgtgca ttagtattag aaccaaaaat tctttgtttg gatgaaccgt tatcaaacct
     2521 agatgccaaa ctacgagttt cgttgagaaa agaattgaaa cgattgcaaa aagaactagg
     2581 aatcactact ctttatgtca cacatgatca agaagaagca ttaacattat cagataggat
     2641 tgctgtgttt aataatggat ttattgagca agttggcacg ccgtatgata tttataatca
     2701 atccgaaact caatttgtct gtgattttat tggctcaatc aataaaatta gccaagaagt
     2761 tcttaaaaaa ttacaaggcg agaataaata ctttaaagaa actgaaggat acatacgctt
     2821 agagcgtgtt aagttagaga aaacttcacc tcaagattta tctataacag gagtaattag
     2881 tgatattgag tttaatggtg tacttattaa gtataaagta gacttgtcga atagtgaaag
     2941 tattcatatt atcgaaaaga atgatggact atcacgtcat ataatcgaag aaaaagtcac
     3001 tatgtacatt aatccgcgtg atataatgca attttaagga gattgtgcat gagaaagagt
     3061 ctaaactgga aagattggct cataagatta ggagttttat ggctaatctt tgccctgatt
     3121 atttatccaa atattgaact tttgtctgga gtgttttata aaaatggttc atttactcta
     3181 gaggcattca ataagattat acactctcag agagcgatga gtagtatatt taatagcttt
     3241 attttggcga tttcaatggt ctttactgta aatattgttg ggacattgat tgttctactc
     3301 acagagtact gggatattag gggttcaaaa atacttaaat taggttatat gagctctcta
     3361 gtatatggag gaattgtatt agcgacagga tataaatttg tttatggcgc taatggtctt
     3421 gtaactaaaa cgctctcaag tataattcca ggtcttgccc ctaactggtt tcaaggattt
     3481 ggtgcagtat tgtttattat gacatttgct tgtacctcaa atcacataat gtttttaaca
     3541 aatgcagttc gtagtgttga ttatcataca attgaagcag ctaaaaatat gggtgcaagt
     3601 cctttaaaag ttttctttag tgtggttttt ccaactttta aacctacgtt atttgcctta
     3661 accatcttaa cttttttgac aggtctttca gcagtttctg ctcctttgat agtagggggg
     3721 aaagattttc aaactattaa cccattgatt atcagtttcg ctaaaactac aagttcgaga
     3781 gatttagcag ctttactagc tatcatgtta ggtttagcaa ctattctatt attgacactt
     3841 ttgaatcatg tcgaaaaagg aggtaattat gtatctgttt cgaaaaccaa ggctagtatt
     3901 aagaagcaga taatttcttc tccattatgg aatactcttg ctcacattgt tgcgtatgta
     3961 ttgtttgcaa tctatatgtt accaatagtt ttgataattc tatactcgtt tacagactcg
     4021 ttgacgatca agacgggaac tttagatcta tctaaattta cgttagcgaa ctatgctaat
     4081 ttatttacag atgctcaatc atttcatcct tacctagtca gcgttgttta tgcaatttta
     4141 gctgcggtaa ttgctacaat tatagcaata gtaatttcac gtattgtaca taaaaacaag
     4201 agtaagttcg ataaattctt tgagtatggt gcactaatac catggatatt gccaggtaca
     4261 ttgattgcac taggattaat gttcacttat aatatacctc atttaatact atttaattta
     4321 gttttagtag gaacagtaat tattttactt attgcatata ctattcaaaa attaccattt
     4381 tcttatagaa tgattcgggc tgtatttttc agtatagata atgatatgga agaagcagca
     4441 cgtagtatgg gtgcatctag tttctacact atggtgcgag ttattatacc gtatatttta
     4501 ccagtcgtat tatcagtagt tgtgttaaac tttaattctt tattatctga ctatgactta
     4561 tctgtattct tgtaccatcc acttttccaa ccattgggaa tcgttattaa acagtctact
     4621 gatgaaacag caactttaaa tgcacaggca atgatgtttg tttattctgt aattttaatg
     4681 attatgtcta gtgcagctct ttatttatca agcctattcc aaggtaaacg aggtaagaga
     4741 taatatgaat ctttcatacg aactgagtat ttgggaaata cttcttaggt gctttttagc
     4801 gattcttttc ggtggcattg ttggctatga gcgaggagtc aaaaaccaag cagcagggat
     4861 tagaacctac ttactagttt gtttgggaac ttgtgttgta atgatgacaa atcagttcat
     4921 cactagtcgt tatggtagcg gtgatcctag tcgaatggga gcccaagtaa ttagtggctt
     4981 gggtttccta ggggcaggaa caatcatggt aactaatcaa aaagttaaag gtttaacaac
     5041 agcagctgga ttatggtctt cagcaactat tggtttagct ataggcattg gtttttatga
     5101 aggtgctatt ttagccggag ttgtactcat agcagtttta actctattta ctcctcttaa
     5161 agattattta aactcgaaaa ctaaaattgc tgattactac ttggttttta gttctttaga
     5221 aggttataat cgtttactta tatatttaaa tacatcgggt attaagattt tagaaattca
     5281 aaatggtata ggaaatcttg atgaagaacg tcaattaaat aaaattaagt caacaaaagt
     5341 gtcctgctat ttatcattaa aattaaacga aaactttgaa catttaaagt taatggaaga
     5401 aatgcataat attgctggtg ttatttatgt tgaagagatt aggtaagggt gactttgtct
     5461 aattttttct atatttctaa tcggagaaaa aaatgaatat aatttttgat ttagggaatg
     5521 tgttgattga atggaataaa gaaaaaattt tatcaaaaat ctgt
//
LOCUS       DAVKZI010000082         5212 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKZI010000082 DAVKZI010000000
VERSION     DAVKZI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.083"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..608
                     /locus_tag="VXB18_002113"
     CDS             <1..608
                     /locus_tag="VXB18_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0383239.1"
                     /translation="TYEEIAADFGVHESNLIRRSQWVEVTLVQSGVTISRTPLSSEDT
                     VMIDATEVKINRPKKQLANDSGKKKFHVMKAQAIVTSQGRIVSLDITVNYCHDMKLFK
                     MSRRNIGQAGKILTDSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHALSKERSKV
                     ENIFAKVETFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(1346..1606)
                     /locus_tag="VXB18_002114"
     CDS             complement(1346..1606)
                     /locus_tag="VXB18_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383240.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
     gene            complement(1665..2216)
                     /locus_tag="VXB18_002115"
     CDS             complement(1665..2216)
                     /locus_tag="VXB18_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383241.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATFIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAP"
     gene            complement(2206..2403)
                     /locus_tag="VXB18_002116"
     CDS             complement(2206..2403)
                     /locus_tag="VXB18_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383242.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(2407..3201)
                     /locus_tag="VXB18_002117"
     CDS             complement(2407..3201)
                     /locus_tag="VXB18_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383243.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(3609..4034)
                     /locus_tag="VXB18_002118"
     CDS             complement(3609..4034)
                     /locus_tag="VXB18_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383244.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEYMTTGDILIEAFKA"
     gene            complement(4163..4546)
                     /locus_tag="VXB18_002119"
     CDS             complement(4163..4546)
                     /locus_tag="VXB18_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383245.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            complement(4568..4774)
                     /locus_tag="VXB18_002120"
     CDS             complement(4568..4774)
                     /locus_tag="VXB18_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383246.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(4761..4922)
                     /locus_tag="VXB18_002121"
     CDS             complement(4761..4922)
                     /locus_tag="VXB18_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0383247.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
BASE COUNT         1707 a         1013 c          755 g         1737 t
ORIGIN      
        1 gaacttatga agaaattgcg gctgattttg gtgttcacga aagcaactta atccgtcgga
       61 gccaatgggt tgaagtaact cttgttcaaa gtggtgttac gatttcaaga actcctctca
      121 gctctgagga cacggtaatg attgatgcga cggaagtaaa aatcaatcgc cctaaaaaac
      181 aattagcgaa tgattctggt aaaaagaaat ttcacgttat gaaggctcaa gcgattgtca
      241 caagtcaagg gagaattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt
      301 tgttcaaaat gagtcgcaga aatatcggac aagctggtaa aatcttgact gacagtggtt
      361 atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca
      421 agccgctaac agctgaagat aaagcctgta accatgcgct atccaaggag agaagcaagg
      481 ttgagaacat ctttgccaaa gtagaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc
      541 atcgtaaacg ctttggatta cgaatgaatt tgattgctgg tattatcaat catgaactag
      601 gattctagtt ttgcaggaag tctattatat atgcacagac atatgaaatc tttttgagac
      661 agcagttatg atatatttat ccattcacaa catcttctgt actaatacta caatattggt
      721 acattttgat tacacaatcg tttcaaaaaa tatgatggaa gcctgagtat tttatagtaa
      781 ttcccttcct atcaactaga tcaaccagtt gagtgttgaa tgttgaaaca ccctagcctc
      841 agcaaaggac tatgatcagc atttcctagc caataggacg ctccaaatca cctattctaa
      901 gtccatcact agcttggtca gtaagataca ggctgcaagg caagactgac gtggttgatg
      961 agattttgga agagtattac aatcatagat tcaccagtag acttgaccgc agatttaact
     1021 atagtagatt gaaactagaa tagtacactt ctgcttctaa aacattgtta gaaatcgatt
     1081 taactgtcct gatcaatttg tcctgttctc gtttcattct accatactaa aaaaccacct
     1141 gaaacaaatc aagtgactag aggataaaaa cgaagactgg gcaaaaagtt ttgaaaagca
     1201 aaaaacgcat aatatcaggt cttgaaaaac cttgatacta tacgtttgat tgtgggaaga
     1261 ttgacttcat tttctcctga aattgaagtt ttttctagtt tccagatata gacgaattca
     1321 atatagccat ctcgctacaa ttattttaac catcgagaaa atttttcaga atttcaaaaa
     1381 tttcattttg atccaatgaa atgtcattat tttgaagaat agttgacttc acaggctcta
     1441 attctatcac aaagcggtgc atgtctgctt ttaccgcact acttgatgtt atagccgata
     1501 acttttcatc tcctagcaag gaagctgtca aacgggtaat gtcattcaaa tgctttttaa
     1561 tggacttact taaaccttga gcacctgtgg cagagcgctc cctcatatcc agccaagctt
     1621 tagccttaaa aataattaat actcaatgaa aatcaaagag caaactaggg agctagctgc
     1681 aggctgctca aaacactgtt ttgaggttgt agatggaagc tgacgtggtt tgaagagatt
     1741 ttcgaagagt atagaccaca attactcaat accgaatacc cctgaatggt ttcttttaca
     1801 tgcaccaata tattataata atcttcatcc aataataagg ctgataaact agcatcttgg
     1861 tcaaaatata agggaatttc tcgaccgtcc ttctttaatg gatattctgg taagatacta
     1921 aatagttcaa tcatagaagg aaactcagaa ttagttgttg taaatcgaaa aagctgcgct
     1981 ttctcatctt tctgacttcc ttgatactct cccaattcta aaaaatgatt caaggtagta
     2041 taaaattcct tattttttac ttcatcaatg atgaccatat cataatcttt tgttgtgcga
     2101 cttttaaatc cttgcgaatc caatacgata aaggtagcag ttcccccaat cagaacataa
     2161 tagttctgaa aatccgcaaa catttcttga aaaataactt tcgtattagc tggcatcatc
     2221 ttctcccaga tactgtaata tcatattttc tagtgcttca ctctcttcct ctatacgtgg
     2281 gtcatcatca tcttttaagg tcaaataaag agaaatcgga tctacaaatt gtttatcatg
     2341 attattttta aaatcattcc aaaactcaga tacaaaagga cgatatttcc atatctctag
     2401 catctttcat tttaaaacat gctgagaaag tggcaaggat aactgattga attttctctg
     2461 ccatatgaca tagctaatat tttcatccgt ttcagctaaa aaagttgaat gcgacaaagc
     2521 ataagcacca ccatatagaa ggttagaaac agattttatc tgctttatat cgccatctgg
     2581 caataaaatc cgttttttga tgggattaaa taaacatgac acggatttta agaataattc
     2641 tttctttgac accgtatatg tgtaaagctt attttgcttg tttaaccaat ataaggcttt
     2701 aaaagtcctc aaacacctat aaattgttga atttggaagt ccagtgactt gtgaaagcaa
     2761 atcaacatct actacttttt gaccttttgt caataaaaag gcaatccacg ttaattgttc
     2821 gctaggtgtt aattccttag ggacttcagt atcattcgca ttgagtacta gtcccaatgg
     2881 agggaagaag aggtttccct taaagtctac aaacggaact ctagcttgaa gtaattgctt
     2941 tttttcactg tctgataact tcgaaaacac caaaacaaca tccatattgg ctttttcacc
     3001 catagtgcga gcctgagtaa caaatgaact caaactcccc cttctctttt ctttaatcaa
     3061 taaaaatgat tccttatgaa aagtcatttg agtatactca aaccttttta caaaactgat
     3121 tggtaaagtc aaagtcagtt cctcaatact gacatcaaca taaaaggatt gaaaaattga
     3181 cattatcttt ttgacattca tgttttttcc ttattctatc atttttatta tattttatca
     3241 ttcggtataa taaaatataa gttttttgat aaaataacca aaaactactc gctatcccct
     3301 ctcacattac cctacatatc gtttgacatg cgactgatag tttaggaaaa cttcaaggag
     3361 aacttttctc tcatccacta tgcaggactt actatttcac ttctactcct ataggctcaa
     3421 tttgacactt ttctttttcg aattgctcat atgcctcctg aatagtgagt tcgatttatc
     3481 caaatttatt tttgtctatt ttgatgaata cttccacgaa gatagtctga aaatgaattt
     3541 gcaccaattt tccttctctt tttaagcata ttattccaga tatgattgcc ctcttattca
     3601 gtaataaatt acgctttaaa cgcttcaatc agtatatctc ctgttgtcat atattctaaa
     3661 gaaaattctt ctacatatga tttaacatct cttaggttat tacttcctaa tatcccatta
     3721 tgctttttcg ctaaggaaat agatgcccct tctcccttac caataatctt gttactatca
     3781 tgatttcttg ttaaatctct atataatgcg tattcttcag ttccaatgtc tatgctcaca
     3841 atctcagctg aacccttagc taccaactgg tctatcctag attttaaatg gggaattgta
     3901 ggtatattga tttcatcata cacctcttgt ggaataacaa ttttacccaa atagagcttt
     3961 tctaaaagat gttcagtgcc aacccataaa aatactgaaa tacaatctgc atcaataaat
     4021 acacgactag tcaaacgaca actcccccct cttcatatag cccatataca atatcatatc
     4081 tgaaagcatc tagtaacagt tcctcatact tcccttgcga aattctgtta ttttctaaaa
     4141 gttgttcagt tgaattaata tattatccta ataccgtttc ctttttactt tctgacaaag
     4201 gacgatataa acttgtatca tagcctaatc ttgaagctgt ctctataaca ctaatatcca
     4261 tatttttaat ttcttctgca tcaaggtatc catcattcct caatctatat aacatagctt
     4321 tatgactgat accataaaac tgacccaatt ttataatatc ttctacttca agatgagttc
     4381 tattggcatt ttctctaatt tcctcaacca tcctatacag tgaagatggg aaaattaaaa
     4441 aataagaagc aaactgatcc gcttttcttt cagtttcatc tccttcacca atcaagataa
     4501 gactgactga actcttcttc acctcatcat aataaagatg atacagttca tgtgctaaag
     4561 aaaatcttta ccttcctaat gacatgtctg aattgactgc aatgagactg aactgagttc
     4621 ctttataaca gactccgcta atattctttc cgagtccata aaataccagc gtcaaatttt
     4681 ctatcttttg taccaattta aaaatatcta tcggcgattc accatcagct cccaactttt
     4741 ttctaagatt tggagcttta ttacttaaat ccattcgtga tattcctttc acctttttcc
     4801 attttggcaa tcatgctttg attcaaagac aaatactcag caatcttatc ttgagtaaga
     4861 tttgaagata ttctaagttc ttttattctt tttccaacat cacatacatt tatcacatac
     4921 atttatcata ttcatacacc tctcataaaa agaatagcac actcttgtca taatttttta
     4981 aataaaaaaa ttatgacaaa acaaggaagc aatttattga tgttgcttaa aaatctaaaa
     5041 ttgatgagtt cctatcaaaa atcgtatctt caacctcaaa acagtactta aagctatccg
     5101 actcggttta cattgtcaaa tttagatttt atttgagcat aactttctag tttgctttct
     5161 gatttttgtt taatatagta gcaaacattg aaggaaatat ctccacaaaa aa
//
LOCUS       DAVKZI010000083         4796 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKZI010000083 DAVKZI010000000
VERSION     DAVKZI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.084"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            47..916
                     /gene="rfbA"
                     /locus_tag="VXB18_002122"
     CDS             47..916
                     /gene="rfbA"
                     /locus_tag="VXB18_002122"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0383248.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAKKEKGATVFGYHVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            917..1510
                     /locus_tag="VXB18_002123"
     CDS             917..1510
                     /locus_tag="VXB18_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0383249.1"
                     /translation="MTDNFFGKTLAARKIEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            1523..2572
                     /gene="rfbB"
                     /locus_tag="VXB18_002124"
     CDS             1523..2572
                     /gene="rfbB"
                     /locus_tag="VXB18_002124"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0383250.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            2638..3489
                     /gene="rfbD"
                     /locus_tag="VXB18_002125"
     CDS             2638..3489
                     /gene="rfbD"
                     /locus_tag="VXB18_002125"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0383251.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAKMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            3552..3886
                     /locus_tag="VXB18_002126"
                     /pseudo
     CDS             3552..3886
                     /locus_tag="VXB18_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272501.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
     gene            4057..4173
                     /locus_tag="VXB18_002127"
     CDS             4057..4173
                     /locus_tag="VXB18_002127"
                     /inference="COORDINATES: protein motif:HMM:NF015247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383252.1"
                     /translation="MPVRLTYDNNYFNDTYQGIPIGGYTQIVEKCWIMKILM"
     gene            4149..4734
                     /locus_tag="VXB18_002128"
                     /pseudo
     CDS             4149..4734
                     /locus_tag="VXB18_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         1526 a          821 c         1088 g         1361 t
ORIGIN      
        1 aggtctaatt ctgaatttca gtgaatataa gaaagggatc ctactaatga aaggtattat
       61 tcttgcaggt ggttcgggga cacgattata tcctttgact cgggctgcat caaaacaact
      121 tatgccggtt tatgataaac ccatgattta ctatccactt tcaacattga tgttggctgg
      181 gattagggat attttgataa tctcaactcc tcaagatttg cctcgtttta aagagcttct
      241 tcaagacgga tctgagtttg ggattaaact ttcttatgca gagcaaccaa gtccagatgg
      301 tttggcacaa gcctttatca ttggggaaga gtttattggt gatgatagtg ttgctttgat
      361 cttgggggac aatatctatc acggccctgg tttgagcaaa atgcttcaaa aagcagccaa
      421 gaaagagaaa ggtgcgactg tctttggcta ccatgtcaag gatccagagc gctttggtgt
      481 ggttgagttt gatacagaca tgaatgctat ttccatagaa gaaaaaccgg agtatcctcg
      541 ctccaactat gcagttacag gtctctattt ctatgataat gatgtagtag agattgccaa
      601 aagtattaaa ccaagtcctc gtggtgaact ggaaattaca gatgtaaaca aggcttatct
      661 agaacgtggt gatttgtctg ttgagcttat gggacgtggc tttgcttggt tggatactgg
      721 cactcatgaa agtttactag aggcttcgca gtacatcgaa acagtccaac ggatgcaaaa
      781 tgttcaggta gcaaacttag aagaaattgc ctatcgtatg ggttatatca gtcgagaaga
      841 tgtattggcc ttagcccaac cacttaagaa aaatgaatac ggacagtatc tgctccgttt
      901 gattggagaa gcatagatga cagataattt tttcggtaag acgcttgcgg cacgcaagat
      961 tgaagctatt ccaggcatgt tggagtttga tatccccgtt catggagata atcgtggctg
     1021 gtttaaagaa aatttccaaa aggaaaaaat gcttccgctt ggatttccag agtctttctt
     1081 tgcagaagga aaattgcaaa acaatgtatc cttctcacgt aaaaatgtcc ttcgagggct
     1141 ccacgcagag ccttgggata agtacatctc tgtagcagat ggagggaaag ttctgggttc
     1201 ttgggttgat ctacgcgagg gtgaaacctt tgggaatacc tatcagacag taattgatgc
     1261 aagcaaggga atctttgttc ctcgaggcgt agctaatggc ttccaagttc tatcagatac
     1321 agtgtcatat agctatctgg tcaatgatta ctgggctctc gagctcaaac ccaagtatgc
     1381 ctttgtgaac tacgctgatc caagccttgg tattgaatgg gaaaatattg cagaagcaga
     1441 ggtttcagaa gcagataaac atcatcccct acttaaggat gtaaaacctt tgaaaaaaga
     1501 agatttgtaa aaaggaaaga atatgactga atacaaaaat attatcgtga caggtggagc
     1561 tggctttatc ggttctaact ttgtccatta tgtttacgag aactttccag gtgttcacgt
     1621 gacagtccta gataagttga cttatgctgg aaatcgcgcg aatattgagg aaattttagg
     1681 taatcgtgtt gagttagttg ttggtgacat tgctgatgcg gagttggtag acaagttggc
     1741 tgctcaagca gatgctatcg ttcattatgc agcggaaagc cacaatgata attcgctcaa
     1801 tgatccatcg ccatttattc atactaactt cattggaacc tatactcttt tagaagctgc
     1861 tcgtaagtat gatattcgct tccaccatgt atcgacagat gaagtttatg gggatctccc
     1921 tttacgcgaa gatttgccag gtcatggaga agggccgggt gagaaattta cggctgaaac
     1981 caagtacaat ccaagctcgc cttactcatc aaccaaggca gcctcagatt tgattgtcaa
     2041 agcctgggtg cgttcttttg gagtcaaggc aacgatttcc aactgttcaa ataactacgg
     2101 tccttatcaa catatcgaaa aattcatccc acgtcagatt actaacatcc taagtggtat
     2161 caagccaaaa ctttacggtg aaggtaaaaa cgttcgtgac tggattcata ccaatgacca
     2221 ttcttcagga gtttggacaa tcttgacaaa agggcaaatc ggtgaaacct acttgattgg
     2281 ggctgatggt gagaagaaca ataaggaagt tttggaactt atccttaagg aaatgggaca
     2341 agctgcggat gcctatgatc atgtgactga ccgtgcagga catgaccttc gctatgcgat
     2401 tgatgctagc aagctccgtg atgagttggg gtggaaacct gaatttacca actttgaagc
     2461 tgggctcaag gcaacaatca agtggtatac agataaccaa gaatggtgga aagcagaaaa
     2521 agaagctgtt gaagccaatt atgctaagac tcaggagatt attacagtat aaaaagcagg
     2581 aaatagctgc tttttattgc tatattggga agagttatat attagaaagg tctagagatg
     2641 attttaatta caggggcaaa tggccaatta ggaacggaac ttcgctattt attggatgaa
     2701 cgtaatgaag aatacgtggc agtagatgtg gctaagatgg acattaccaa tgaagaaatg
     2761 gttgagaaag tttttgaaga ggtgaaaccg actttagtct accattgtgc agcctacacc
     2821 gctgttgatg cagcagagga tgaaggaaaa gagttggact tcgccatcaa tgtgacgggg
     2881 acaaaaaatg tcgcaaaagc atctgaaaag catggtgcaa ctctagttta tatttctacg
     2941 gactatgtct ttgacggtaa gaaaccagtt ggacaagagt gggaagttga tgaccgacca
     3001 gatccacaga cagaatatgg acgcactaag cgtatggggg aagagttagt tgagaagcat
     3061 gtgtctaatt tctatattat ccgtactgcc tgggtatttg gaaattatgg caaaaacttc
     3121 gtttttacca tgcaaaatct tgcgaaaact cataagactt taacagttgt aaatgatcag
     3181 tacggtcgtc cgacttggac tcgtaccttg gctgagttca tgacctacct agctgaaaat
     3241 cgtaaggaat ttggttatta tcatttgtca aatgatgcga cagaagatac aacatggtat
     3301 gattttgcag ttgaaatttt gaaagataca gatgtcgaag tcaagccagt agattccagt
     3361 caatttccag ccaaagctaa acgtccgcta aattcaacga tgagcctggc caaagccaaa
     3421 gctactggat ttgttattcc aacttggcaa gatgcattgc aagaatttta caaacaagaa
     3481 gtgagataag tagtagaatg attttctagt ctaataaaag aggcagataa tgaactccaa
     3541 aggagcttaa gatatacaat tatcttgttg ttggtgctgg tctctttggt gcagtctttg
     3601 cccatgaagc agccttaaaa ggaaaaaagt aaaagttatt gaaaaacgaa atcatatcgc
     3661 gggtaatatc tatactcgtg aagaggaagg aattcaagtt catcaatatg gtgctcatat
     3721 cttccatact tctgataagg agatctggga gtatgtaaat cagtttgcag agtttaaccg
     3781 ttataccaat tctcctgttg caaactataa gggtgagatt tataaccttc cttttaatat
     3841 gaatactttc aataaactct ggggagttgt aacgccagca gaagcacaag ctaagattga
     3901 ggaacaacgt gctattttaa atggtaaaac tcctgaaaat ttggaagaac aggcgatttc
     3961 tcttgtaggt acagacatct acgaaaaatt aatcaaagac tatacagaga aacagtgggg
     4021 caaatcaact actgaacttc catcctttat tattgtttgc cagtacgcct gacctatgat
     4081 aacaattatt ttaacgatac ctatcaaggg attccaattg gtggatacac tcaaatagtt
     4141 gaaaaatgtt ggatcatgaa aatattgatg tagaaacaaa cgttgatttc tttgtgaata
     4201 aagagcaata tctgaaagat tttcctaaga ttgtctttac tggtatgatt gatgaattct
     4261 ttgactataa gttgggcgaa ctagagtact gtagtcttcg ttttgaaaat gagaccttgg
     4321 atatggaaaa ttaccaagga aatgcagttg tgaactatac ggatgcagaa accccatata
     4381 ctcgcattat tgaacacaaa cattttgagt ttgggagtca agcaaagact atcattacta
     4441 atagaacatt ctaaaacatg ggaaaaaggt gatgagcctt attatccagt taataatgat
     4501 cgtaataatc atttgtataa atcatataaa aaacttgctg atgagcaagg gaatgttatc
     4561 tttggtggcc gcttaggaca ctatcgttat tacgatatgc accaagtaat tggagcagct
     4621 ttgcagtgcg tgagaaatga gttagattca tactcaatga aaatcaaaga gcaaactagg
     4681 aagctagccg caggttgctc aaagcactgt tttgaggttg cagatggaag ctgacgcggt
     4741 ttgaagagat tttcgaagag tataaacaag taaaactgac taccagttat tattta
//
LOCUS       DAVKZI010000084         4749 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKZI010000084 DAVKZI010000000
VERSION     DAVKZI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.085"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..1027)
                     /locus_tag="VXB18_002129"
     CDS             complement(join(<1..532,531..1027))
                     /locus_tag="VXB18_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0383253.1"
                     /translation="MKSTKEEIQTIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEIIE
                     LLDCNQTTIWRNVKKYEEFGLDSLLQETRGGRNHAYMTVEEEKAFLARHLKATEAGEF
                     VTIDALFQAYKKELGRSYTRDAFYQLLKRHGWRNITPRPEHPKKADAQTIVASKNKIS
                     IQEDKKKRFKTSRPFHKVRLMYQDEAGFGRISKLGSCWSPIGVGPHVHSHYIREFRYC
                     YGAVDAYTGESFFLRAGGCNTEWMNVFLEELSQAYPDDYFLLVMDNAIWHKSSILKIP
                     TNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRILEDVMNQLQDVIQGLEKEVIK
                     SIVNRRWTR"
     gene            1283..2088
                     /locus_tag="VXB18_002130"
                     /pseudo
     CDS             1283..2088
                     /locus_tag="VXB18_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            2105..2683
                     /locus_tag="VXB18_002131"
                     /pseudo
     CDS             2105..2683
                     /locus_tag="VXB18_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            2696..2866
                     /locus_tag="VXB18_002132"
     CDS             2696..2866
                     /locus_tag="VXB18_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383254.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(3377..4723)
                     /gene="gdhA"
                     /locus_tag="VXB18_002133"
     CDS             complement(3377..4723)
                     /gene="gdhA"
                     /locus_tag="VXB18_002133"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0383255.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT         1515 a          850 c          907 g         1477 t
ORIGIN      
        1 tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccagtc cttgtatgac
       61 atcttgaagt tgattcatga catcttccaa aattcgaaag gctttattct taaatccacg
      121 tttacgaatc tctttccaca cttgttcaat ggggttcatc tctggtgtgt atggaggaat
      181 aaatgcaaaa ccaatattag tcggaatctt taagatactt gatttatgcc atatagcatt
      241 gtccataacg agtaaaaaat aatcatctgg ataagcttgt gaaagctctt ctaaaaagac
      301 gttcatccac tcagtattac atccaccagc tcttaagaaa aatgattcgc ctgtataggc
      361 atcaacagct ccataacaat agcgaaattc tcgtatatag tgactatgga catgtggacc
      421 tactcctatt ggagaccaac aagatcccag tttactgatt ctaccgaaac cagcctcatc
      481 ttggtacatc aagcgaacct tatgaaaagg tctactggtt ttaaagcgct ttcttgtctt
      541 cttgaattga gattttattt ttagacgcga caatggtttg agcgtctgct ttcttaggat
      601 gttctggacg tggcgtaata tttcgccaac catggcgctt caacagttga tagaaggcat
      661 cacgtgtgta ggaacgacct aactcctttt tataagcctg aaataaggca tcaattgtaa
      721 caaattctcc tgcctctgta gccttcaaat ggcgggcaag aaaggctttc tcttcctcaa
      781 ctgtcatata tgcatggtta cgaccaccac gtgtttcttg aaggagagag tcgagtccga
      841 actcctcata tttttttaca tttcgccaaa tcgttgtttg attacagtct aaaagctcta
      901 taatctcttt ataagatttg cccatcagac gaaatagaac gatttgaagg cgtttatgat
      961 atttagctgt acgagagtct tttaaaagtg ttttgatggt ttggatttct tctttagttg
     1021 atttcatatc actattgtat aatgcttttt gattttagtc tagtataaat agcgagaaat
     1081 atctatccta tcttctagaa tgtcttccaa acgaggaaac tctcgtaaac aaagaggttt
     1141 tagaggccta tttaccgtgg actaaagttg tacaagaaaa gtgcaaataa gaaatctcca
     1201 gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatagact tcctgcgaaa
     1261 caaaatatgg tataatagtt ctatgaatta tgaagcaagt aaacaactaa ccgatgcacg
     1321 atttaagcgt cttgttggtg ttcaacgcac gacttttgaa gagatgttag ctgtattaaa
     1381 aacagcttat caacttaaac acgcaaaagg tgggcgaaaa cctaaattaa gcctagaaga
     1441 ccttcttatg gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc
     1501 tgatcttggt attcacgaaa gcaacttaat ccgtcggagc caatgggttg aagtaactct
     1561 tgttcaaagg tggtgttgcg atttcaagaa ctcctctcag ttctgaggac acggtaatga
     1621 ttgatgcgac ggaagtaaaa atcaatcgac ctaaaaaaag aattagcgaa ttattctggt
     1681 aaaaagaaat ttcacgctat gaagactcaa gcgattgtca caagtcaagg gagaattatt
     1741 tctttggata tcgctgtgaa ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga
     1801 aatatcggac aagctggtaa aatcttggct gacagtgatt atcaagggct catgaagata
     1861 tatcctcaag cacaaattcc acgtaaatcc agcaaactca agccgctaac agttgaagat
     1921 aaaacctata accatgcact atctaaggat agaagcaagg ttgagaacat ctttgccaaa
     1981 gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg ctttggatta
     2041 cgaatgaatt tgagtgctgg tattatcaat catgaactag gattctagtt ttgcaggaag
     2101 tctattatca aaaataccat caggattata taagattgat acaggaaaag ttttatttga
     2161 tggtataaat attaatcaaa tagataaaaa aatattaagt caaaatttag gagtagttcc
     2221 acaggattca tttttattga accgaagtat tcttgataat ataactttaa agaacgaagt
     2281 tacttcacaa aagatagagg aagtttgtaa agcagttcaa atctatgatg aaatcatggc
     2341 tatgccgatg aaatttaata ctatcatctc agagatgggt tcaaatattt caggtggtca
     2401 aagacaacgg atagcactgg cacgtgcatt aataaataat cctagtattg taattttaga
     2461 tgaagcaact agtgctttag acactattaa tgaggaaaga ataacaaagt atataaaaag
     2521 tcagggctgt actcaaataa ttgtagctca tagattgtca acgattaagg atgcggatat
     2581 tatttttgta atgaaaggtg gtaagattgt tgagtcagga aatcataagt acttaatgga
     2641 gcttggtgga gagtactaca gcttatatac aaaaaggaaa tgaggtgtaa agaaaatgaa
     2701 gaaagaaaat gaatatgtaa ttttaacaac agcctcacta ggggtgatga ttggaatagt
     2761 gtttgcaatt tttttagatt ttccagttga atatggtatt tctttaggct tgttgaatgg
     2821 aatagtattg ggttcgctga ttgtttacaa aaacaataag aattaagcat aattttttgc
     2881 tgtaaactaa ggagtagaga tggctatagt tgaaattata aatctaacaa aaagctttaa
     2941 agatattgaa gttattcata acacttaaat aatagagcaa ctacagtagt agcttaaaaa
     3001 catgattaaa tcgctattct taggagtagc ggtttttctt tttgtttaat actctttgaa
     3061 aatctcttca aaccacgtca gctttgcctt gccgtactca agtacagcct gcggctcgct
     3121 tcctagtttg ctctttgatt ttcattgagt ataaaaaggg ttaagtaagt atagtaaatt
     3181 gaaataagat atgaacaaat cgattagaaa agtcaaatta atttctagaa gtatgttaga
     3241 aattggtttg aattccgcaa tcaatttgtt cagtttttat ttcatttcat ttcattttat
     3301 ttaattagat tttccaattt tttaattcaa gctaaaaatc cccaatcgta gtgattgagg
     3361 attgagtaaa taaatcttaa acaatacctt gtgcaatcat ggcatttgct acattttcaa
     3421 aggcagcaat gttagctcct gcaaggtagt ctttatcaag accgtatgtt tctgaagtcg
     3481 ttttagctgt gttgaagatg tttgtcatga tgtctttgag atggccatca acttcttcac
     3541 gagtccatga gaggcgaaga ctgttttggc tcatttcaag agctgaaacg gctacaccac
     3601 cagcgttggc agcttttgca ggtccgtaga agataccatt ttctttgtaa actttgatgg
     3661 catcaaggtc gctcggcatg ttggcacctt cagatacaca gataacgcct tgagcaacca
     3721 aacgtttagc tgcttcaccg ttgatttcgt tttgagtggc acatggaaga gcaatgtcat
     3781 agtttccagc gtaagtccat acagtacctt cgtggtaggt tgcagttgct ttttcagctg
     3841 catactcagt caaacgagca cgacgttttt ctttaacatc aaccaaaaga tcgaagtcga
     3901 taccattttc atcgatgaca taaccatttg agtcagaaac agaaataaca gttgcaccga
     3961 gttcagttgc tttttgaaga gcatattgag caacgttacc agaacctgaa ataacgactt
     4021 tcttaccagc aaagctgtta ccgttagctt tgagcatttc ttcagtatag taaaccaaac
     4081 cgtaaccagt tgcttctgga cgaatcaagc taccaccaaa tccaagaggt ttaccagtca
     4141 agacaccagc atcaaattgg ttaagacgtt tgtattgacc gtaaaggtaa ccaatttcac
     4201 gtccaccaac accgatatca ccagcaggta cgtcaagtga tggtccgatg tgtttttgca
     4261 attcagtcat gaagctttgg cagaagcgca tcacttcagc atctgtttta cctttaggat
     4321 cgaagtctga tccaccttta cctccaccga taggaagtcc agtcaagaca tttttaaaga
     4381 tttgttcaaa tccgaggaat ttcaagatcc cttggtttac agttgggtgg aaacgaagtc
     4441 cacctttgta tggtccaaca gctgagttga attgaacacg gtaaccacgg tttacttgaa
     4501 tttttccatc acggtcaacc caaggaacac ggaaagaaac cacgcgctca ggctcagtaa
     4561 tacgtgccaa gatattttct tcgatatact cagggtgttt ttcaaataca ggttctaaag
     4621 tgttgaaaaa ttcttcaaca gcttggagga attcagcctc gtgcccgtta cgagctttca
     4681 cagtttcaaa cacgctttgg atatattctt tagcagatgt catatcgttc tccttttatt
     4741 gtcatattt
//
LOCUS       DAVKZI010000085         4294 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKZI010000085 DAVKZI010000000
VERSION     DAVKZI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.086"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            12..1037
                     /locus_tag="VXB18_002134"
     CDS             12..1037
                     /locus_tag="VXB18_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0383256.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1027..2034
                     /locus_tag="VXB18_002135"
     CDS             1027..2034
                     /locus_tag="VXB18_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0383257.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2034..3041
                     /locus_tag="VXB18_002136"
     CDS             2034..3041
                     /locus_tag="VXB18_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0383258.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3041..3835
                     /locus_tag="VXB18_002137"
     CDS             3041..3835
                     /locus_tag="VXB18_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383259.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT         1556 a          634 c          729 g         1375 t
ORIGIN      
        1 aaggagtttt tatgaaaaac aaattttttc taatagctat tttagctatg tgtatagttt
       61 ttagcgcttg ttcttctaat tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc
      121 ctgataaaat agttttagat catgctttcg gtcaaactat attagataaa aaacctgaaa
      181 gagttgcaac tattgcttgg ggaaatcatg atgtagcatt agctttagga atagttcctg
      241 ttggattttc aaaagcaaat tacggtgtaa gtgctgataa aggagtttta ccatggacag
      301 aagaaaaaat caaagaacta aatggtaaag ctaacctatt tgacgatttg gatggactta
      361 actttgaagc aatatcaaat tctaaaccag atgttatctt agcaggttat tctggtataa
      421 ctaaagaaga ttatgacact ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac
      481 cttggcaaac tttatggaga gatatgatta aaattgattc aaaagcctta ggtatggaaa
      541 aagaaggtga tgagttaatc aaaaatactg aagctcgtat atccaaagaa ttagaaaaac
      601 atccagaaat caaaggaaaa atcaaaggaa aaaaagtatt atttactatg attaatgctg
      661 cagatacatc aaaattctgg atttatacta gcaaagatcc aagagcaaat tatttaacag
      721 atttaggtct agttttccct gaatcattaa aagaatttga gagtgaagat agttttgcaa
      781 aggaaatttc tgcagaagaa gcaaataaga taaatgatgc tgatgtaatc ataacttatg
      841 gtgatgataa aactcttgaa gctttacaaa aagatcctct tttaggtaaa ataaatgcaa
      901 ttaaaaatgg tgccgttgct gtaattccag ataatacacc gttagcagcc tcatgcactc
      961 caacaccact ttcaataaac tatactattg aagaatacct aaatctttta ggaaatgcat
     1021 gcaaaaatgc gaaataaaaa acaaataaac ctaggcataa tttttgtaat ctgcctaggt
     1081 cttcttatta caatattttt gtcattaaag cttggaacaa aagaaattaa tatcagagat
     1141 tttttagcag cttttggaat gggcaataca aatgatgatt ttattaaatc aattatatat
     1201 aaaagaatac ctagaactat ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt
     1261 gtattgatgc aatcagttac tagaaaccca atagctgatc caggtatact cggtataaac
     1321 acaggagcaa gtcttagtgt agtaattggt ctttcttttt taggaatttc atcaagcata
     1381 agccatataa gttttgcaat cattggtggc ttagtaagtg caatttttgt atacgcgatt
     1441 gctgtaagcg gaaaagcagg ccttacccct ataaaactag ccttatcagg aacttgtgtt
     1501 agtatggctt taagcagttt tgtaagtttt ttaattttac cgaataataa cgtcttagac
     1561 aaatttagat tttggcaaat aggtagcctt ggagcagcta cattatcttc tatatctaca
     1621 ctactacctt ttataatttt aggtcacttg atagctatat ttatttcatc agatttaaac
     1681 gctttagcta tgggtgatga aatggctgtt ggtcttggag ttaatgttaa taggataaga
     1741 tcacttgcaa taattgcaag tgtgctttta tgttcaagta ttactgcaat tggtggacct
     1801 attggcttcg taggtcttat agttcctcac ttttgtggct tatttataag caaagatata
     1861 cgcacaatga ccatttcttc atcttttata ggtgcagagc tcttgcttat atgtgatata
     1921 atcggccgta tgttaggtaa accaggtgaa attgaagtag ggataattac tgcaataatc
     1981 gggggtccag tacttattta tgtaactatg aaaaatagag gggttaataa ctaatgcaaa
     2041 atttaattat aggtattcaa aaaagaaaaa atagaataac actattctcc tcactatttt
     2101 tattaataat aatcagtcta tcatttttca ttttacttat cggagatgaa agttattctt
     2161 tttcaacttt gattaaagtc ttaaatagtg aaactgttcc tggagctagt ttttcgatta
     2221 tggaaattag attaccaaaa ttattagcag gaattatagc tggctggtct tttggattgg
     2281 caggatttat ctttcaaact atgttaagaa atcctcttgc aagtcctgat ataatcggtg
     2341 tcacaagttc ttcatctatt gcagcggtct tttgcatatt ggtattaaaa acaaatagtt
     2401 taactactgg aattatttca ataacttgtg gactaacatc atctttaata ttatttttac
     2461 tagctaaaaa agatggtttt tcagcagcaa gactgataat attaggtatt ggttttcaag
     2521 ctgtcacaag agcaggcacc tcatttttat tgttgaaagt agcaagatat gaattacaag
     2581 aagttatgag atggctcagt ggctctttat cttttacaaa gttagatgac atacctcttg
     2641 ttctaatagt aagtattatt gctactatat tagttttatt ttttaataaa agactagaaa
     2701 ttattgaact tggtgaagaa atagcaatcg gacttggagc aaatcccgag ctttcaaggc
     2761 ttgttttaat tttttgcgct gtatctttaa ctgctttttc tacttcaatt acaggaccaa
     2821 tagcttgtat atctttttta gctggtccca tagccttaaa tattggcaag aaaagaagcc
     2881 caatattagc tggattggtt ggaattttac tagttttgtt atcagacata ttctctcaaa
     2941 atattttacc agctagatat ccagtaggtg ttgtaactgg cttgttaggt tcaccatact
     3001 taatatactt actaataaaa atgaacagga gaaatatata atgaaaggtc tgtggtcaaa
     3061 taatcttacc tgcggttatg atgaaaaaat aatcttggaa aatataaata taaaaatacc
     3121 tgaagaaaaa atatcagtta ttattgggtc aaatggttgt gggaaatcaa cactcattaa
     3181 aaccttgtct cgacttataa agccattaga gggagaagta ttgcttgata ataaatcaat
     3241 taattcttat aaagaaaaag atttagcaaa acacatagct atattacctc aatctccaat
     3301 aatccctgaa tcaataacag tagctgatct tgtaagccgt ggtcgtttcc cctacagaaa
     3361 gccttttaag agtcttggaa aagatgacct tgaaataata aacagatcaa tggttaaggc
     3421 caatgttgaa gatctagcaa ataacctagt tgaagaactt tctgggggtc aaaggcaaag
     3481 agtatggata gctctagccc tagcccaaga tacaagtatc ctacttttag atgagccaac
     3541 tacttacttg gatatctcat atcaaataga actattagac ctcttgactg atctaaacca
     3601 aaaatataag acaaccattt gcatgatttt gcacgatata aatctaacag caagatacgc
     3661 tgattaccta tttgcaatta aagaaggtaa acttgttgca gagggaaagc ctgaagatat
     3721 actaaatgat aaactagtta aagatatctt taatcttgaa gcaaaaatta tacgtgaccc
     3781 tatttccaat tcgcctctaa tgattcctat tggcaagcac catgttaact cttaataatt
     3841 gaatattgga attcatttaa aagtcgcaac ttttgaactg accctcaaaa gttaggccaa
     3901 aaaactaact aaaggaggtc agttttttaa tggcaactac agcacagaat ttaagataaa
     3961 attagtaaaa gaatatcatg aatgaaaaat aggatataga gaataacagc aatattaaaa
     4021 agatcaggac tgataataaa caaaaagaaa gtacaacgac tagttcaaaa gctaaaactt
     4081 caagtaaaaa gttattcaag aaaatctaga aaatactcat cctacaaagg acgggtagga
     4141 aaaatataag acaacaaaat aaaaagaaat atttattacc gaaaaaaagg ggaaatcgag
     4201 tcaagtacca acaggctcat ctattccaaa aagatattta ctcgatggaa aaactcctag
     4261 aattagtgct acaaatattg acaatggtat ctta
//
LOCUS       DAVKZI010000086         4226 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKZI010000086 DAVKZI010000000
VERSION     DAVKZI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.087"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            713..1705
                     /locus_tag="VXB18_002138"
     CDS             713..1705
                     /locus_tag="VXB18_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0383260.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VXB18_002139"
     CDS             1707..2525
                     /locus_tag="VXB18_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0383261.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VXB18_002140"
     CDS             2527..3312
                     /locus_tag="VXB18_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0383262.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3410..3628
                     /locus_tag="VXB18_002141"
     CDS             3410..3628
                     /locus_tag="VXB18_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0383263.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3613..3810
                     /locus_tag="VXB18_002142"
     CDS             3613..3810
                     /locus_tag="VXB18_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0383264.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4086..>4226)
                     /locus_tag="VXB18_002143"
     CDS             complement(4086..>4226)
                     /locus_tag="VXB18_002143"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383265.1"
                     /translation="SSKHCFEVVDRTDEVSNHTHGKATLTWFEEIFEEYKSKTFVNRD
                     TL"
BASE COUNT         1176 a          729 c          907 g         1414 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 aggaagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaactctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctttcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggttggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaaggaga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaatttct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa ggcagttgtc gctgagattt tgaaggattt
     3421 gccagaatgg tttggaatcc cagaaagcac acaaacctat atagaaggaa ccacgacact
     3481 gcaagtttgg accgcctatc aggagagtga tttgactgga tttgtaagct tatcctattc
     3541 gagtgaagat tgtgcagaga ttgattgtct cggcgtaaaa aagcttatca aggtagaaaa
     3601 attgggagcc aattgcttgc tactttagag agtgaagctc gtaaaaaagt tggttatctg
     3661 caggtcaaaa cagtggcaga agcttctaat aaagattatg atcgaacaaa tgacttttat
     3721 cgaggtcttg gctttaaaaa gttagagatt tttcctcaac tatggaatcc gcaaaatcct
     3781 tgtcagattt tgattaaaaa gcttgaataa tattacttga catctattct cagagtgcta
     3841 tactgtaagt gtaatcgccg atttagctta gttggtagag caaggcactc gtaaagccta
     3901 ggttataggt agataaacga ctgaggattt gaaaaaatag ataggtagaa gataaccgtt
     3961 aagccttact cttagcggtt atttatattg tttaatagcg ctaatatttt atcaattatg
     4021 cctgttttcg tgtttctggt agttgttcaa gtttattgct actatttttg atggtatgaa
     4081 tgtgcttata atgtatcccg gttaacgaaa gttttggact tatactcttc gaaaatctct
     4141 tcaaaccacg tcaacgtcgc cttgccgtgc gtatggttac tgacttcgtc agttctatcc
     4201 acaacctcaa aacagtgttt tgagct
//
LOCUS       DAVKZI010000087         4217 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKZI010000087 DAVKZI010000000
VERSION     DAVKZI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.088"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..274
                     /locus_tag="VXB18_002144"
     CDS             <1..274
                     /locus_tag="VXB18_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383266.1"
                     /translation="YLLYKVGFLGIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQD
                     AVASKQIVVINEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            588..1565
                     /locus_tag="VXB18_002145"
                     /pseudo
     CDS             588..1565
                     /locus_tag="VXB18_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1546..1797
                     /locus_tag="VXB18_002146"
     CDS             1546..1797
                     /locus_tag="VXB18_002146"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383267.1"
                     /translation="MFQLGDKTRIIFAIIGASCILVSMYLIPLIKTENKFWEILLFIL
                     GVLLIGIALLSQKKINFEIVLVSSQSFIASGLELLSFKQ"
     gene            1943..2317
                     /locus_tag="VXB18_002147"
     CDS             1943..2317
                     /locus_tag="VXB18_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0383268.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2525..3427
                     /locus_tag="VXB18_002148"
     CDS             2525..3427
                     /locus_tag="VXB18_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383269.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLEFPLDFVISMSL
                     AFCSLILSKIALDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSV
                     DDLKSRMIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3483..3836
                     /locus_tag="VXB18_002149"
     CDS             3483..3836
                     /locus_tag="VXB18_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0383270.1"
                     /translation="MELVLPNNYVVIDEEEMMYFDGGAYLSKRACQGICVALAMSPGT
                     FIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            3833..>4217
                     /locus_tag="VXB18_002150"
     CDS             3833..>4217
                     /locus_tag="VXB18_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383271.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQS"
BASE COUNT         1404 a          550 c          755 g         1508 t
ORIGIN      
        1 ttatttacta tataaggttg gatttttggg aatcatttac gataatgaag cattaagaga
       61 tttgtcaaaa caatatttaa acaaaaatat ttcggaatta caagatggtt ctttcgaggg
      121 cggtatacaa gatgctgttg cctctaaaca aatagtagtt ataaatgaat ttatagcttg
      181 tttaaattcc agatgcgtgc catcccaata tgatagattt ttttataaag atagacctta
      241 tattttttcc agaaagagtc ctattaaggg gtgaaaattt gttacatttg gattaacaag
      301 tgtcctaggg attagaaata actctagtat agctagatat ttttgagtaa ctagaaatat
      361 cattagtcta cccatatgat tgccagaaaa gatggctgat gaatcttatt tatactgttg
      421 cagtaggcgt tgtctaggat aaataagcta tcttgatggg ggagattgga ataattttag
      481 tagaaacatt aaaggattat ggacaagtag cgcaggatta ggtgatgcaa tgtgctaagt
      541 tggcttggtg ttagcagtag tattatttaa caatggaaag tagactaatg aaaaataagc
      601 gttatttttt tgacacaatt ttaataattt tactgcttat aagcacgata ttttgtgtca
      661 gcccagtatt tataaaattg gacatcttag gaactccctc tcatgccatc ttaacctttg
      721 tattggcgat accgttattc tatattttgt ctcaatgctt acatactttg ctattactag
      781 tttcctcaat cttttgtaaa ttaagaccaa tttattttta ttttatattt gtgatcatta
      841 taggagctag gaaatactat cgaattctct ttcaccaact aatgggattt agtccaggaa
      901 tagcagtgtt ttataaggag agtcaaacaa ctaagaatct gtttaaattt tactacttct
      961 tgtactttac aacactaatt tcatactatt ttttctttac ttttgtgtat gacaaatcgt
     1021 tgcttttgcc tcttattcca ttttctatta tcatagcatt agtacaaaaa ctttatagaa
     1081 ttgagaatca acaattattt ctgttaaaat caaaggtact aacaatactg gaatctaaga
     1141 gggattgtga gtttaatctt caggattatc atgaaatttg gaaattgcaa tcaaaatctg
     1201 agttgccatg cgtggcttta tcttatatca gtttgatcaa gccatatctt tcagagagcg
     1261 tgcgtgaaca aattgattta ttagaagtta agcgatttaa aaaaataaat catccaatat
     1321 cactttatgg tatgttggat gttataaaat taaatctata tttacggcat tataatgaaa
     1381 aaaataaata tgaatcaatg ttaaagaaaa ttttataggt aagaccagac tttgttttaa
     1441 tcgagcagaa tattgatgat agtttaaata gctcgcaacc attatcttta tctttagcca
     1501 tttcagaaat ccaacttttg cttgaagtgt atatggggat caaacatgtt tcaattagga
     1561 gataaaacca gaataatatt tgccattata ggggcaagtt gcatattagt cagtatgtat
     1621 cttattccac ttattaaaac tgagaataaa ttttgggaaa tacttttatt tatattaggt
     1681 gtattgctaa ttggaattgc gttactaagt caaaaaaaaa taaattttga aatagtatta
     1741 gtgagttcgc aatcatttat tgctagtggt ttagaactgt taagtttcaa acaataattg
     1801 attttaaacc ttaggtaacc tataaaaaca aataaggtag agaaaggata tcttatatag
     1861 gtagctaagt gataaaaaca cagtcgtcta tcacttgtta ggaaactatc ctaactatgc
     1921 ttaataaaaa aggagaaaat aaatggaact cgtattacca aataattatg ttgctcttga
     1981 gcaagaagag atgatgtatc ttgatggggg attttctatt ctgagatggc ctgttgcaac
     2041 agccattaat atagctttta atggtgtttt aggtggagga gcaatcagtc tagttagaaa
     2101 ttatattcgt aattatggtt tgcggcgagt tacaagcgca attgctggag cagctgcaag
     2161 atatgttggg gtacgagttg caaatagagt ggcaggattt gcactgtctg ctattaatgg
     2221 atttgcagct tggatgtcaa ttggcgatgc tattacaaca atctgggcca acaatgatgt
     2281 aaataggaga gacccaaatt taaacgcctt gtggtaacta gatatgggta ttaaaatgga
     2341 aaaaattttt gttattattt tttttgtatg tctatttata tcatccataa cttttttagc
     2401 ctatgatttt gttagcgaag aaataaaaaa gttgattatt tggattaatg tcgttttttt
     2461 gattttaatc atagcaatga taatttatcc aaaattaaga aaatgataag gacactgtaa
     2521 aattatgatg cgtaaactaa ttgttttctt actaatgctc cctctttttg tcttgtggct
     2581 agagttgcat gtcctagtga ataacttact attgaatcta gaatttcccc ttgattttgt
     2641 gattagtatg agtcttgctt tctgtagttt gattttatca aaaatagctt tagacatact
     2701 atacgcattg aaagatttgt acaagaaaga agctcttatt acgatttttc cttttatttt
     2761 tataggcagg aagaaagtaa atgtgaggtt ctcaccctat ttttcattcc atcgaaaaag
     2821 tttgtcggtt gatgatttaa aatctagaat gatatggagt tttattcttg aaatagctat
     2881 tatcctagta tttattttaa aaattccttt tgcaatcatc atgcttacta caatattttt
     2941 ctggactata atggatatca atcatctcgt ttttaataag acggaatttc tttttaatca
     3001 aaataaatgg gaaaaagaag attcgtttga aagcgatttg acgaaaacgt taaaggataa
     3061 gatacaaaaa tcagatctca gttattctga cttaatgtct cttcagctgt atgatgcgat
     3121 gaaccaatcc acctttttaa cggatagtga actttttgag gatattctga gtaaaattga
     3181 agattctcat aacacccttc tgtgtacagg tcttgtcgag ttactgctgt atgagatttc
     3241 tattagtaac aataacaact ggcaagaaaa ggttgataaa attaggatac acctcatcag
     3301 aatcaatcaa ttagattttt tctattatac aagttggtta aggcaaaatt ttgatttctg
     3361 tatgaataga gagtatcata aaatgaaatc tcggaaatta ttactgagta ataaaaagat
     3421 agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt tcaactaagg aggagaaaac
     3481 aaatggaact tgtattacca aataattatg ttgtgattga tgaagaagaa atgatgtatt
     3541 ttgatggggg agcttattta agcaagcgtg cttgtcaagg aatttgcgta gctttagcta
     3601 tgagtccagg aacttttata gcattgactg gagctgcagt tttaaccaaa aaactaataa
     3661 actatattaa ggttggaggt cttggaggct ggcttattgg tgcagcagca ggtgtattgg
     3721 ctacagcagc aggaaaaata gcttactgta ttggatatgg tgctcttaat agaggttgtg
     3781 atattagcgg gaacccttat ccttgggatg gatttatatc tgcgacagta agatgaataa
     3841 tgtagataag attcgaaaaa tacatattat cgtatgttgg atgtatatat ttttatcatt
     3901 cagggcgatt ataaatgaca cggagtattt tttgcttatt tttttagctt ttatctactc
     3961 aatagtatca ctacctctat attctgtgaa aaataaaata gtatctatct gtctagccat
     4021 aaattcgatt ctgttaatga gtttccccat tttaatcaat aagtttttcc cagaaagttt
     4081 tttgacttat accgtattaa taagtgtttt tatcctagag ttagcaatct ttcatttaat
     4141 tggggaagat tttgctacta aattgactaa cgaatataag aaaattagtc agtttagaag
     4201 caaggtgtct caatctc
//
LOCUS       DAVKZI010000088         4060 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKZI010000088 DAVKZI010000000
VERSION     DAVKZI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.089"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..151
                     /locus_tag="VXB18_002151"
     CDS             <1..151
                     /locus_tag="VXB18_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0383272.1"
                     /translation="LTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYME
                     RYRDR"
     gene            117..431
                     /locus_tag="VXB18_002152"
     CDS             117..431
                     /locus_tag="VXB18_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383273.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1105..1290
                     /locus_tag="VXB18_002153"
     CDS             1105..1290
                     /locus_tag="VXB18_002153"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383274.1"
                     /translation="MKKKGGMHVDNDWNGLAELFANLITKYAGVLDLDNLPDPTPAKN
                     QEMKNSFDMAKTQIETD"
     gene            1382..3061
                     /locus_tag="VXB18_002154"
     CDS             1382..3061
                     /locus_tag="VXB18_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0383275.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            3329..3895
                     /locus_tag="VXB18_002155"
     CDS             3329..3895
                     /locus_tag="VXB18_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383276.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         1573 a          505 c          853 g         1129 t
ORIGIN      
        1 tttaacttca attattaggc aagctttaaa aaatactgaa tataaagatc aaatatctag
       61 cacagtattg ccagatatca aaattaaatt accgatagac agtagaggta ctccagattg
      121 gaattacatg gaaagatata gagatagata aagagagaga gggagagata gataaaaagt
      181 ccacccccat tttttatgga gaattcaaaa atgtaaggtt aagcaaagaa gaatataaaa
      241 atctaaaaga aaaattaaac tcacacacag atataatgat aaataaacta tccagataca
      301 tggaaagcag tggtaagacc tatcaaaacc actatgtgac aatcttaaaa tggtatgaag
      361 aagataaaga caaactaaga cagaaaggtt taaataaaaa aatgaattat gatgtaggag
      421 aatctttata gataaaaaga ggtggaaagg cactattaaa gactttaagt ctaaaaaggt
      481 atcaaagtat gccagagata aaaaaatata aatatgacac tttaaaggcg attagaaaat
      541 taaagaaatg ctagaagact tttagatgac agttaccaag agggtctaat tttcactgct
      601 acttatgcag tgggaattgg acctttttat ataagcaaat tctatttcaa aattggttac
      661 caagaaagac ttcttttcac tgttaagtat aagagggtaa tttatagaat tttgttacat
      721 caagataaat attttatgat ggtcaaattt taaaaagatt aataactctc gataaatttt
      781 gaaccttaac aattgaatag accaagacaa gacgttaatt atttttggag cgtaataacc
      841 tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa agttctgcta agcaaaaaga
      901 aagtgagcga taagtaagag tttgaatata gggagggata ccctatccgc tatgaagaaa
      961 atgaggataa tgatacttct ttagtgaaag ccggctcatc ttaacagggg cggtggtgag
     1021 attccaatgt tgctgatcct aagcacccgt taatgtcatg aaacttagtt agatgagaaa
     1081 gttatagatt gattatataa gagtttgaag aaaaaagggg ggatgcatgt ggataatgac
     1141 tggaatggac tggctgagtt gtttgcgaat ctaattacaa agtatgctgg tgttttagat
     1201 ttggataatc tgccagatcc aacgccagca aaaaatcaag agatgaaaaa tagttttgac
     1261 atggcaaaaa cacaaattga gacggactaa taaaagtgtt ataatatact tgaaatgata
     1321 gtccaaactt aaattaaaaa aattatatat gatatagaaa aattatattg agattaatac
     1381 tatgtcaaaa gaaaaaataa aagtatacct ctatacacga gtatctacgt caatacagat
     1441 agaggggtat tcgttagagg cacaaaaatc acgaatgaaa gcttttgcta tttacaatga
     1501 ttatgaaatt gttggagagt atgaagatgc cgggaagtct ggcaagtcta ttgaaggtag
     1561 aatacagttc aatcgaatga tggaagatat aaaatctgga aaagatggag tatcttttgt
     1621 tcttgtgttt aagttatcaa gatttgcaag aaatgccgct gatgttcttt ctacacttca
     1681 gataatgcag gattatggag ttaatcttat ctgcgttgaa gatggcattg attcatctaa
     1741 agatgctggg aaactaatga tttctgtttt atcagctgtg gctgaaatag aaagagaaaa
     1801 catccgtatt caaacaatgg aagatcgcat tcaaaaagca agggaaggaa aatggaatgg
     1861 tggctttgct ccgtatggat ataaacttga agacggcaag ctgtttataa atgaggaaga
     1921 ggcagttgca ataagaacga ttttcgacca gtatgtaaat actacgatag gagccaatgg
     1981 gatatctaaa tacttagaga atcatggaat tagaaaaatc ccaagacaga atggtaagaa
     2041 tcctttgttt gatgcaggtc ttataagaaa gatattaaag aatcctgtat ataatgggaa
     2101 aatagcattt ggaagaagaa ctttagaaaa agttcatggt acaagaaatg aatataagca
     2161 ggttgaacaa gatgaatatc taatatctga agggatacat gaagctatag tttccgatga
     2221 agtttggcaa gctgctcagg ttaagctaaa atctcaagca aagaaatatg agcatgtgaa
     2281 taaaggaaaa gatacacgca cacacttgct ttctggaatt gtaaaatgcc cgatatgtgg
     2341 agtgggaatg tttgggaaca agtgtatcaa gaaaaagaaa gatggcacaa agtataaaga
     2401 tttttattac tatggttgta aacataggca gatgataaga ggtcataagt gtacattcag
     2461 taagcaaatt agagaagaat tgttagatga tgctgttgca gaggtgattg tcaagatagt
     2521 aagtaatccg aaatttgctt ctatgatgca agaaaaaatc aacatgaagg tggatacctc
     2581 tgaaatagaa aaagaaatag ataattacca aaaggaattg agaaagagtc attctacaaa
     2641 gtttaagcta attgaggaaa tagataattt agatgttgaa gataagcact ataagagaag
     2701 gaaacaggat ttagatgata gactatatcg tatgtatgac aaaatagatg aattagaatc
     2761 atcactaatt gatgcgaaag caaagaaaca gactattgaa gctgaaaaac ttacaggaga
     2821 taacatatat aaggttctga tctattttga taagctctat aaagtcatga atgatgtaga
     2881 gcgtaggcag ttaatttcag ctttgatttc tgaaattcaa gtttatgaag aaaaacaatc
     2941 taacggacaa tggctaaaat ccattacttt taaactacca attatagaag aaaatctcaa
     3001 cataggtttg gataatgatg aacaagttga atgtgtaagt ttattagaga aacgtagtta
     3061 atcctcaaaa ggttccccaa accttttgag tcccactgac gcatcacgct gaggcggtat
     3121 cactgcttgt acgagttgaa gcatcagcga agtaaaagta gatgttcagc caatgcgacg
     3181 aggtgagacc gaaggtcgat aaggtgtgtt ctgggtatag gactcgtaaa gtaagtagga
     3241 aatatgatga gatgatacag agagcctgaa ttggtcaggt gacgtgctta tttacattag
     3301 cctgataatg aaaatggaga gattatcgat ggttatattg gaattgtacc aaaatgatta
     3361 ttctaaagat ttagtagcat ttgattccat agaagatggg aaagcctttg tagctcaaat
     3421 cccgggatac actctggaaa cagaagatgg ttttgaagtg gagtatttta atcctaaaaa
     3481 cataccggat tatatggaaa ttatttttaa cggaaatatt gttcctttat ctaaatttat
     3541 gttcgatcct gaggaaaatg taaacattat ttggaaagag atttcaaatt tatccctcaa
     3601 aaatgataga gtgatcgaag gatattcaaa aattgatgca tatgtcgtta acaaccatga
     3661 agttaaagcc tatgtcgaaa caagagaaac gaactatcgt aaagcaaaag acttcttaga
     3721 aagccgcgga tatgaaatcg acagaagctt tttcggaagt gaagacggtg aagcgattct
     3781 ttacagaaaa aaagggatcg aagtttggca tttcttgtgt cacttagacc caatgtttgt
     3841 agagattgaa gatgtagaag gatatgttaa agaagaagtt ggagagattc aatagtcaac
     3901 caaagttcct tgtgagtata tacctttgct agtaaaagag tcaaaacgtt ataacgaagg
     3961 ggggaagaaa acccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag
     4021 ccgctcataa tttatactag atttgataac tgatttgaga
//
LOCUS       DAVKZI010000089         3966 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKZI010000089 DAVKZI010000000
VERSION     DAVKZI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.090"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            256..1659
                     /locus_tag="VXB18_002156"
     CDS             256..1659
                     /locus_tag="VXB18_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV0383277.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1848..2466
                     /locus_tag="VXB18_002157"
                     /pseudo
     CDS             1848..2466
                     /locus_tag="VXB18_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            2481..3221
                     /locus_tag="VXB18_002158"
     CDS             2481..3221
                     /locus_tag="VXB18_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383278.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3224..>3966
                     /locus_tag="VXB18_002159"
     CDS             3224..>3966
                     /locus_tag="VXB18_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383279.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLTGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSC"
BASE COUNT         1391 a          502 c          761 g         1312 t
ORIGIN      
        1 agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata tggggggaat
       61 ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat attaagtttg
      121 atagaatttc ttggagattt tgttatggat tataatttca atttggagca tcctttcttt
      181 ttcactaata atgattatag tacagatact agcataaagt actaagtaag tctgcctttt
      241 aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat tggaaaattt
      301 gttgaaagac aagggtggaa aatacacatt agttcagagt ataacagttc acatgaattg
      361 ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca tcttagtaca
      421 gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc tggtaaattt
      481 attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt agaaagtgcc
      541 ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga agcaccaata
      601 tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt tgttattgat
      661 gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt taaaattcca
      721 aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga taaaaaacag
      781 ggagactttc cctttattat agataatgca attagatttt caaacagtgg tgggatatat
      841 aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag accgtataca
      901 ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg caaagcacta
      961 aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa gatctgggag
     1021 cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg ggttaccaat
     1081 aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag agtttcaaag
     1141 atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt atatcatcaa
     1201 gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat aatagactgg
     1261 gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc ccctggtttt
     1321 agagcatggc gagaaacact tcccagtgag atagattggt atggtattag acaaatagct
     1381 cattatttat acatgccact agtaactaca tcggatttga catacaacta tgtaagtcaa
     1441 accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga acatatagat
     1501 tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga gaatatttcc
     1561 aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga gcaagatata
     1621 caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc ttagcaaacg
     1681 ataaagtttt agggccgata caatcaattg cctattcatt aaataagata aatacaacca
     1741 aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt atagacgctg
     1801 aacatgataa taacggactg tatacttcat caatagatgt gatacacatg aaagatgttg
     1861 tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag tcaccattta
     1921 gggtattatt aacaggaact tctggtagtg ggaaaacaac gattttaaat ttaattaatg
     1981 gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa aagagttcag
     2041 attcaatacc aacagttgat cagacaccat atatttttga cactactatt cgtgagaacg
     2101 taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg ttaaaaaagg
     2161 taaatctata tgaagaatta gaaaagatag atatactaaa ttatcaatgt ggtgaaaatg
     2221 gtagtaattt gtctggaggt caaaaacaaa aaatagcttt agctagagct ctgattagaa
     2281 ataataaagt gtacttattt gacgaaatat cagctaattt agataatgat aattcaaatt
     2341 ccatacatga tattctgttc aatttaggta tttcatttat tgaagtttca catcattatg
     2401 acttaaatga caagagatac actgatatat aaattggaaa atggaacact tttcaaaatt
     2461 aagtgattgg aggcaagaat atggataaag attatatatt aaaagtgaaa gggctgtatc
     2521 atcaattttt actgggaaac aataaaacgt tgcaagtgct gaaaaatgtt tctctttctg
     2581 cttcgagagg agaatttata agtattctag gaattagtgg ttctggaaag tcaactttat
     2641 taaaatgtat ttctagtttg cttgaaccaa caagtgggga agtaatttta aatggaatca
     2701 acccctataa aatcagaaat gcaaaattgt caagtataag acgtaacgaa gtatctttta
     2761 tatttcaagc atacaattta ataccttccc tgccggtaat agaaaatata gcacttcctt
     2821 tgcgattatc acaaaaaaaa ttaactatta aaaatgtaga aaacttactc aaaagaatga
     2881 agtttaatgc tggcttaaac gattttgttg gaactctgtc tggtggagaa caacagaagg
     2941 ttgctatagc tagagcggtt attgctgata gtgatataat atttgctgat gagccaactg
     3001 gggctttaga cagcgtttct cgtgaagtaa tttttgaatt attgagagag ttagtagggg
     3061 cgggtaagtg tgtaattatg gtaacgcacg atatagaatt ggcctcgaaa actgatcgtg
     3121 cattaatatt gaaagatgga aaaattttca aagaacttca tagacctagc ggggaagagt
     3181 tgtataaaat cttagaggta caatcaacta cggaggaata gagatgctca gattagttta
     3241 ctatcaattt ttacataata agaaacaatg gttaggcgtt tcaccagtaa tttttgtttc
     3301 gagtttagtt atgggattgg ctgttaatgg ggtaattaat gttgagaata attcgcaagt
     3361 atttgtcgga cttccagatc ctaaaccaat ttttatgttt ccgatagtat tcggaggagt
     3421 aacattattc tttgtgctct ctaacataat aaatatgttg gttgaaattt ttagagatga
     3481 ttacgaactt ctggaggtgt tgggagcaag tctccttcaa ctatcatttc ttgtgggggg
     3541 acagattttt atcatttcct cgattattag ttttattgca tatctatgct ctatatttgt
     3601 tacgtcaaat tattattatt ttttacaata ctttttcggg gaaaatatat tacctgatat
     3661 ccaatttcaa acgagtgctg ttggatgtat cattacagta gtgttgattt catttttagc
     3721 ctttctaagt ggttgctttt atacgttcaa gaagattaga aataggaaga gttctaaaat
     3781 aaggcatgtt ctttcaatag taaaaagaat actgctattg actggtttta gtgttatctg
     3841 gttgctttct ttgcaacaaa ttttccaaga tagcacaatt ttagcgaagg cccagataat
     3901 attcaatatt gtaatcttag atattgtgat tatttatcaa ttatctcctt ttatacagtc
     3961 atgttt
//
LOCUS       DAVKZI010000090         3870 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKZI010000090 DAVKZI010000000
VERSION     DAVKZI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.091"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..418
                     /locus_tag="VXB18_002160"
     CDS             <1..418
                     /locus_tag="VXB18_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0383280.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            628..3747
                     /gene="phtE"
                     /locus_tag="VXB18_002161"
     CDS             628..3747
                     /gene="phtE"
                     /locus_tag="VXB18_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0383281.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTAGYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1451 a          630 c          751 g         1038 t
ORIGIN      
        1 taaaaataag gcagaccaag atagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 tgcggaggcc ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccta tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtagatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 atttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggatttat catgagtcac ggtaatcata atcattactt cttcaagaag
     2041 gacttgacag aagagcaaat taaagctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaggtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcatcatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcagcctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3181 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3241 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3301 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3361 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta
     3421 tctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3481 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3541 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3601 gatcctgtac aagaaaaatt agaaaaattt acagctggtt acggattagg cttagatagt
     3661 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3721 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     3781 gaagttctct caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt
     3841 aatatataaa atttcttgac atacaactta
//
LOCUS       DAVKZI010000091         3738 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKZI010000091 DAVKZI010000000
VERSION     DAVKZI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.092"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            130..357
                     /locus_tag="VXB18_002162"
     CDS             130..357
                     /locus_tag="VXB18_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383282.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            645..3542
                     /gene="nanA"
                     /locus_tag="VXB18_002163"
     CDS             645..3542
                     /gene="nanA"
                     /locus_tag="VXB18_002163"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0383283.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLSGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1280 a          623 c          845 g          990 t
ORIGIN      
        1 ctaacactta taaaaagtga tagaatctat ctttatgtat atttaaagat agattgctgt
       61 aaaaatagta gtagctatgc gaaataacag atagagagaa gggattgaag cttagaaaag
      121 gggaataata tgatatttaa ggcattcaag acaaaaaagc agagaaaaag acaagttgaa
      181 ctacttttga cagttttttt cgacagtttt ctgattgatt tatttcttca cttatttggg
      241 attgtcccct ttaagctgga taagattctg attgtgagct tgattatatt tcccattatt
      301 tctacaagta tttatgctta tgaaaagcta tttgaaaaag tgttcgataa ggattgagca
      361 ggaagtatgg tataaatagc ataagctgat gtccatcatt tgcttataaa gagatatttt
      421 agtttaattg cagtggtgtc ctggtagata aactagattg gcaggagtct gattggagaa
      481 aggagagggg aaaattggca ccaatttgag atagtttgtt tagttcattt ttgtcattta
      541 aatgaactgt agtaaaagaa agttaataaa agacaaacta agtgcatttt ctggagtaaa
      601 tgtcttattt cagaaatcgg gatatagata tagagaggat cagtatgaat cggagtgttc
      661 aagaacgtaa gtgtcgttat agcattagga aactatcggt aggagcggtt tctatgattg
      721 taggagcagt ggtatttgga acgtctcctg ttttagctca agaaggggca agtgagcaac
      781 ctctggcaaa tgaaactcaa ctttcggggg ggagctcaac cctaactgat acagaaaaga
      841 gccagccttc ttcagagact gaactttctg gcaataagca agaacaagaa aggaaagata
      901 agcaagaaga aaaaattcca agagattact atgcacgaga tttggaaaat gtcgaaacag
      961 tgatagaaaa agaagatgtt gaaaccaatg cttcaaatgg tcagagagtt gatttatcaa
     1021 gtgaactaga taaactaaag aaacttgaaa acgcaacagt tcacatggag tttaagccag
     1081 atgccaaggc cccagcattc tataatctct tttctgtgtc aagtgctact aaaaaagatg
     1141 agtacttcac tatggcagtt tacaataata ctgctactct agaggggcgt ggttcggatg
     1201 ggaaacagtt ttacaataat tacaacgatg cacccttaaa agttaaacca ggtcagtgga
     1261 attctgtgac tttcacagtt gaaaaaccga cagcagaatt gccaaatggt cgagttcgcc
     1321 tgtatgttaa tggtgtttta tctcgaacaa gtctgaaatc tggcaatttc attaaagata
     1381 tgccagatgt aacgcatgtg caaatcggag caaccaagcg tgccaacaat acggtttggg
     1441 ggtcaaatct acagattcgg aatctcactg tgtataatcg tgctttaaca ccagaagagg
     1501 tacaaaaacg tagtcaactt tttaaacgct cagatttaga aaaaaaacta cctgaaggag
     1561 cggctttaac agagaaaacg gacatattcg aaagcgggcg taacggtaaa ccaaataaag
     1621 atggaatcaa gagttatcgt attccagcac ttctcaagac agataaagga actttgatcg
     1681 caggtgcaga tgaacgccgt ctccattcga gtgactgggg tgatatcggt atggtcatca
     1741 gacgtagtga agataatggt aaaacttggg gtgaccgagt aaccattacc aacttacgtg
     1801 acaatccaaa agcttctgac ccatcgatcg gttcaccagt gaatatcgat atggtgttgg
     1861 ttcaagatcc tgaaaccaaa cgaatctttt ctatctatga catgttccca gaagggaagg
     1921 gaatctttgg aatgtcttca caaaaagaag aagcctacaa aaaaatcgat ggaaaaacct
     1981 atcaaatcct ctatcgtgaa ggagaaaagg gagcttatac cattcgagaa aatggtactg
     2041 tctatacacc agatggtaag gcgacagact atcgcgttgt tgtagatcct gttaaaccag
     2101 cctatagcga caagggtgat ctatacaagg gtaaccaatt actaggcaat atctacttca
     2161 caacaaacaa aacttctcca tttagaattg ccaaggatag ctatctatgg atgtcctaca
     2221 gtgatgacga cgggaagaca tggtcagcgc ctcaagatat tactccgatg gtcaaagccg
     2281 attggatgaa attcttgggt gtaggtcctg gaacaggaat tgtacttcgg aatggacctc
     2341 acaagggacg gattttgata ccggtttata cgactaataa tgtatctcac ttaagtggct
     2401 cgcaatcttc tcgtgtcatc tattcagatg atcatggaaa aacttggcat gctggagaag
     2461 cggtcaacga taaccgtcag gtagatggtc aaaagatcca ctcttctacg atgaacaatg
     2521 aacgtgcgca aaatacagaa tcaacggtgg tacaactaaa caatggagat gttaaactct
     2581 ttatgcgtgg tttgactgga gatcttcagg ttgctacaag taaagacgga ggagtgactt
     2641 gggagaagga tatcaaacgt tatccacagg ttaaagatgt ctatgttcaa atgtctgcta
     2701 tccatacgat gcacgaagga aaagaataca tcatcctcag taatgcaggt ggaccgaaac
     2761 gtgaaaatgg gatggtccac ttggcacgtg tcgaagaaaa tggtgagttg acttggctca
     2821 aacacaatcc aattcaaaaa ggagagtttg cctataattc gctccaagaa ttaggaaatg
     2881 gggagtatgg catcttgtat gaacatactg aaaaaggaca aaatgcctat accctatcat
     2941 ttagaaaatt taattgggaa tttttgagca aaaatctgat ttctcctacc gaagcgaaag
     3001 tgaagcgaac tagagagatg ggcaaaggag agatgggcaa aggagttatt ggcttggagt
     3061 tcgactcaga agtattggtc aacaaggctc caacccttca attggcaaat ggtaaaacag
     3121 cgactttcct aacccagtat gatagcaaga ccttgttgtt tgcagtagat aaggaagata
     3181 tcggacagga aattattggt atagctaaag gaagcatcga aagtatgcat aatcttcctg
     3241 taaatctagc aggtgccaga gttcctggcg gagtaaatgg tagcaaagca gcggtgcatg
     3301 aagttccaga atttacaggg ggagttaatg gtacagagcc agctgttcat gaaatcgcag
     3361 agtataaggg atctgattcg cttgtaactc ttactacaaa agaagattat acttacaaag
     3421 ctcctcttgc tcagcaggca cttcctgaaa caggaaacaa ggagagtgac ctcctagctt
     3481 cactaggact aacagctttc ttccttggtc tgtttacgct agggaaaaag agagaacaat
     3541 aagagaagaa ttctaaacat ttgattttgt aaaaatagaa ggagatagca ggttttcaag
     3601 cctgctatct ttttttgatg acattcaggc tgatacgaaa tcataagagg tctgaaacta
     3661 ctttcagagt agtctgttct ataaaatata gtagattgaa ataagatgtg aacaactcta
     3721 tcaggaaagt caaattaa
//
LOCUS       DAVKZI010000092         3507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKZI010000092 DAVKZI010000000
VERSION     DAVKZI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.093"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..1032)
                     /gene="phtA"
                     /locus_tag="VXB18_002164"
     CDS             complement(<1..1032)
                     /gene="phtA"
                     /locus_tag="VXB18_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV0383284.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNISNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELE"
     gene            complement(1286..3019)
                     /gene="ptsP"
                     /locus_tag="VXB18_002165"
     CDS             complement(1286..3019)
                     /gene="ptsP"
                     /locus_tag="VXB18_002165"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0383285.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(3025..3288)
                     /locus_tag="VXB18_002166"
     CDS             complement(3025..3288)
                     /locus_tag="VXB18_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0383286.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT          922 a          755 c          673 g         1157 t
ORIGIN      
        1 ttccaattca gacatttgtt cataagggat aaagtggtaa tggttaccat gagggacagc
       61 tacacctctg gcggttcgac ttgtgatttg cgctgggtcg aaaacaaggc catcagattc
      121 tacatggcgt tgactcaaag gcagtttgta gagctgtttc aagagactat caatgtcatt
      181 actttgactt gcttgactgt tagtgttgct gttgttgctt atgttagtat ttgtagttcc
      241 tggattgctt acagaaggta cccagtttgt tcttgaagtg ttatcgctat tttgtcggcg
      301 ataggttctt gaatttgaca gatttccccg accagatagg aaggcttctg cagcagctaa
      361 ctcgctagct gataactcat tcttaggaat gtaatggtaa tggtcgccgt gaggaacgat
      421 ataagcatca cccgtgtcct caatgatatc agaagcatta aagatataac catcatctgt
      481 ggtgtagcgt ccctgtgaac gtgcaaaggc taccgcacca tcgtttgctg aagtccctcc
      541 ttcacgatgc tgactatgtt cttgtttttg ccgattgatt tcttcttttg tacggacatt
      601 atccgcgtgg gcagcatcct taaggtaaac atagtatttt ccatctacct tgataacata
      661 tccacccttg acctcattaa caatatcctc atcttttagc ttatagtttg gatctttcat
      721 gagtaattct tcactgaaaa tcgcatcata aggaacctta ccattgtaat aatgatagtg
      781 gtcgccatgt gaagtgacat agccttggtc tgttatcttg atgacgattt gctcagcatt
      841 gattccttca cgcttgctaa cctcatcagg agtcaaattc tccgtttttt gcgtcgcttg
      901 ttttccatct atataggaaa cacgattatt ttccttaacc gttctagctt gatacagtcc
      961 caactcgtaa gaacaaacac ttaaaatcaa agctgccgca gaaccaacaa ggtatttctt
     1021 attaattttc atcgaaactc tctttctatt tgatatttct agttgcaatt catttctaaa
     1081 ttgcagaaac tcctctctat tacttaactg gttaatagtt tactcctaaa tctccaactt
     1141 gtcaagaatt ttatgaacca tttaagtatt ttttgttctg accactactt tttcaaggtt
     1201 ggactttcta taaaaaagat tttcttgaaa attcttttta aaatatcaaa aaaatccctg
     1261 taactgagtt gcagggattt ttcgattaat caaaattaac gtattctttt tgaagttcaa
     1321 gaacttcttc cattgttgag cattctgtaa gggcacggtt tgcgtactct tccatcttag
     1381 ctgtgtcgag tttcttcatc aagctgcgtg tacgaagtac agatgttgct gacatagaga
     1441 actcatccaa gcccattccg acaagaagtg gaacagcttg ttggtcacca gccatctcac
     1501 cacacatacc agcccattta ccttcagcgt gagctgcttt gatcacattg ttaatcaagc
     1561 gtaggattga tgggttgtat ggttggtaaa ggtatgaaac ttgttcgttc atacggtctg
     1621 ctgccattgt atattggatc aagtcgtttg taccaattga gaagaagtca acttctttag
     1681 caaattggtc tgcaagcata gccgctgcag gaatctcgat catgatacca acttggatgt
     1741 tatccgcaac tgcaacacct tcagcaagaa ggtttgcttt ttcttcatca aagactgctt
     1801 tcgctgcacg gaattctttc aagagcgcaa ccattgggaa catgatacgc aattgaccgt
     1861 gaacagacgc acgaagaaga gcacggattt gtgtgcggaa catagcatct ccagtctcag
     1921 agatagagat acgaagagca cggaatccaa ggaatgggtt catttcgtga ggcatatcga
     1981 agtaaggaag ttccttatct ccaccgatat ccattgtacg aacgacaaca ggtttaccgt
     2041 tcattccttc aagaacagcc ttgtatgctt catactgctc atcttcagtt gggaagtctt
     2101 gagaatccat gtacaagaac tctgtacggt aaagtccaac agcttctgca ccgttgttgt
     2161 taacaccttc aacgtctttt ggagtaccaa tattggcagc caactcgaag tgtttaccgt
     2221 cagcagtcac tgtttgagca tctttcaaaa gtgcccattc agctttttgt ttcgcatagg
     2281 cttcaccagc tgctttaaat tctgccgctt gttcatctgt tgggttgata atcacttctc
     2341 cagtgatccc gttaacagca aggatgtcac cgtctttaac gatttcagtg atgttatttg
     2401 tacctaatac agcagcaatt tcaagtgtac gtgccatgat agctgagtgg cttgtacgtc
     2461 caccaatgtt ggttacaaaa gcttttacaa agtttttgtc caattgagct gtatctgaag
     2521 gagtcaagtc atgcgcaatc acaatcactt cttcattgat agaagctggg tttggcaatt
     2581 ttttaccaag aaggtttgcc aatacacgtt ttgtcacgtc gcggatatcc gctgcgcgtt
     2641 cttgcatgta tgggttgtct tccatgcctt caaagatagt gataaacata tctgtaactt
     2701 ctttcagacc tgcttctgca ttcactttct tcgcacggat agtttccttg atttggctga
     2761 tcatttctgg gtcagcaaga accattaagt gagcatcaaa aacttgagct gcttcttcac
     2821 cgagcgtacc tactgctttc tcgcgaataa cagaaagctc gtcttgtgat gcctgtagag
     2881 cggcatcaag gcgagcttct tctgcgtttg tatcttcgac tgtaatagtc tcaaatgaca
     2941 aatccggctg aacgagtaga tatgcttttg caactgcaac accgtcagat gctgcgattc
     3001 ctttaagcat ttctgtcatt tcccttatgc caatccttct ttttccattg tttctgagat
     3061 tgcagcgata gcgtcatctg catctgcacc ttcagctgag atagttacgt cagcaccttg
     3121 gccaacacca agactcataa cacccataat tgatttaagg ttaactgatt tacctttgta
     3181 ctcaagagtg atatctgaag caaatttgct agcagtttgt accaacaatg ttgctggacg
     3241 tgcgtgaata cctgtttctg ccactacgtg gaaatcttta gaagccatag tttgactctc
     3301 cttttgttct ttcttttttt gagttatatg tgataaccct tacaatttag tattatacca
     3361 tcttctagga tttttttcaa gcattttctg gattttcctt caatttcctt tcagataact
     3421 tgctgaaaat cttctatctt agagaacaaa acacaggata tagtttcttc aaaaacaatt
     3481 tataggataa tcattgctat ttcacaa
//
LOCUS       DAVKZI010000093         3341 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKZI010000093 DAVKZI010000000
VERSION     DAVKZI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.094"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>3341
                     /locus_tag="VXB18_002167"
     CDS             <1..>3341
                     /locus_tag="VXB18_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0383287.1"
                     /translation="FLHGLTKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMT
                     QSALNDLYYKLKNLTYYPYNLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKG
                     GLRGRISADSKAGNDTQYSYEGTITKQIKQQDGIEAKIQAQIEAADAAFDAEFDKREK
                     AITDAIELAKARAEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQ
                     EAKRIGLDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVE
                     ALSRTKNELDGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQ
                     AGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDVTFPVAL
                     VNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVFIRFGTN
                     YGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRANSLDAGVSRLT
                     EGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNAT
                     KDKANKSELTQTAEELASKIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYTATIDSE
                     SKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANKN
                     GIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESNQTTNEWLFNFNQEGTIWI
                     WMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSLEAGVNRLTEGLRTKADISS
                     LNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVS
                     EAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNLE
                     PDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLG
                     MYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDW
                     NPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESARQA
                     KAVRELVNRDFVGKATYQEDVKGIN"
BASE COUNT         1051 a          657 c          809 g          824 t
ORIGIN      
        1 ttcttgcatg gcttgaccaa gagtgagatt gagtatcaga tagctggtat cacttgtaag
       61 acggacaaga agtctctgac ggtcggtatg aagacaggtc ggtctttgga actggacaat
      121 gtcttcatga cccagagcgc tttaaatgac ctgtattaca aactgaaaaa cctaacttac
      181 tatccgtata atctcaacta ccaagggcat ttactgcttg aggttgggca gtgggtaacc
      241 attcagacca acaagaaaga aacctttaaa gttcctgtct taagtcagag ctttactttc
      301 aaaggtggtc taagaggtcg tatcagcgca gatagtaaag ctggaaatga tacgcagtat
      361 tcttacgagg gtacgattac caagcagatt aagcaacaag atggcattga agcgaaaatc
      421 caagcgcaga tagaagcagc agacgcagcc tttgacgctg aatttgacaa acgtgagaaa
      481 gctatcacgg atgccatcga acttgccaaa gccagagctg aagaagtcaa gagagaactg
      541 tctgacacta tcaatcagcg ctttaatagc tttgacaacg ggccattgaa agaaactaag
      601 cgcaaggctg aggaagcttt gcgaaatgct ggcgcaagta ccctgcttgc acaggaagct
      661 aagcggattg ggctggattc tgtcgctaga cttgaagcgt ttaagtcgca gactacgagc
      721 gcacaaacgg ctctgtcggg tgacttggac gctctgaaac ggactatcgc gaatgatatt
      781 cgaccgaagc aagcacaggc tgaagctgag attgccaagc aagttgaagc acttagccgg
      841 actaaaaatg aactggatgg cgtgaagtca gcgcaagcga cgtatgagga gacgacgact
      901 cgtagactgt cagaactgac caacttggcc aatggtaaag ccagcaagtc agaactcacg
      961 caaacagctg aggagctggc tagtcggatt gcgagtgtgc aggcaggtag ttcacggaat
     1021 tacttcagga attcacgttc aagaacgttc acaacaggag gtcaagcggt atacgactat
     1081 cgaacattca tagttcctga tttctggaag aacagtgaca ggttcaagcg tgattatgtt
     1141 cgcatatctt ttgatgtgac tttccctgtc gccctagtaa atgacatgcc tgctatggtg
     1201 cattttagtg ctcatccatg gtatgcctac agaaacttaa tttttaaagg tggaactgtc
     1261 gaacgccaac attttgagtt tacgattgac ttgtctagtt cttctgagga ctatcagact
     1321 aataatgtgt tcattcgttt tggtactaat tatggatttc ctgctggtct gcaggttgtc
     1381 attgagaacg ctatgttatc ggttggtaat tattttccag cctatcaacc agcgtatgaa
     1441 gaccaagaag accgtgtctc agtagtcgaa tccaacttta agcagcgtgc taattcactc
     1501 gacgctggtg taagccgtct gactgaaggg cttagaacta aagccgatat cagctcactc
     1561 aatgtgactg ctgaaaatat ccggcaatct gtgaagagcc ttgagacaga cacgcagaac
     1621 aagctaaatc agaagttgag tcaggctgaa tttgaggtgc gagccggctc tatccgtcag
     1681 gaaatcctga acgcaaccaa ggataaagcc aacaagtcag aactcacgca gacagctgag
     1741 gagctggcta gtaagatagc gagtgtgcag gcatccggtc gaaatctatt cttgaactca
     1801 ctattcaagc aggatattcc aaaaacagga atttggacaa cgagtacata tacggctact
     1861 atcgatagcg aaagtaagta tcttggacac aaggctctta aaattatagg tctgaatcca
     1921 tctggccgtg atggaggtaa tcccaaggtt acttatccag ctctgggtca attcgggaaa
     1981 gtaattcccg gaagtacgac taatcaagat gtaaccatta gtttttatgc taaggcaaat
     2041 aaaaatggaa taatgctaag atctcgatta gggaatatcg gatataaaac tggaaatgtg
     2101 acattgtcga cagaaattaa gcgatatgtt gtccatattc caaaaggttg gacaaacgaa
     2161 tccaatcaga ccacaaatga atggttgttc aatttcaacc aggaaggaac catttggatt
     2221 tggatgccga agtttgaaat aagcgatgta gatacttctt attcagaagc tcctgaagat
     2281 atagaaggtc agatttcaac agttgaatcg accttcaaac aacgagccaa ctcgctcgaa
     2341 gctggtgtga atcgtctgac tgaaggcctt agaactaaag ccgatatcag ctcactcaat
     2401 gtgactgctg aaaatatccg gcaatctgtg aagagccttg agacagacac gcagaacaag
     2461 ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ctggctctat ccgtcaggaa
     2521 atcctgaacg caaccaagga taaagcagat aagactttag ttgtatctga agctgggaaa
     2581 ttgcgtgaag aattttcaaa aatgaaggtg ggaggacgga atctatggat aaaatccaag
     2641 acggttggag ctgtaattga aaaattacct gaaaaccacg tcacaggtca aaaagaatgc
     2701 tataggctag agaacaactc tactttaacg ttcaaccttg aaccagattt cagctcaagg
     2761 ttgtaccaaa aagttacttt tagcgcttgg atcaagtacg aaaatgtagt ccaaggtcga
     2821 aatttttgga atgtatttaa ttgcttcaaa cattatcttt ttagaaaaaa tagtgagacc
     2881 ggagtacaga gtggtccaga ttatgctacg cttggtatgt ataaaggttc ggcagattgg
     2941 aaatatatta cattcactta tgactactct gaaaaaacaa attttgatca attgaagaca
     3001 tcattgcgat tcaatcttga aggtgctaca agcggtacag cttgggtaac aggaatcaag
     3061 gttgaaatcg gtagtgtggc gacggactgg aatcctgcgc ctgaggacgc tgatggtctc
     3121 atcactgagg ctaaggctac ctttgagcgg acagctcagg gcttgcgaac cgacttatca
     3181 gctattcagg aatatgtaaa taaagacggt cagcgacagg aagccctaca gcgctatact
     3241 cgtgaggaga gcgcgagaca agcgaaagca gtccgtgagc tggtcaatcg tgatttcgtt
     3301 ggtaaggcta cttatcaaga agatgttaag ggtatcaatc a
//
LOCUS       DAVKZI010000094         3317 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKZI010000094 DAVKZI010000000
VERSION     DAVKZI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.095"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>3317
                     /locus_tag="VXB18_002168"
     CDS             <1..>3317
                     /locus_tag="VXB18_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0383288.1"
                     /translation="FLHGLTKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMT
                     QSALNDLYYKLKNLTYYPYNLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKG
                     GLRGRISADSKARNDTQYSYEGTITKQIKQQDGIEAKIQAQIEAADKDFDQKVDKIKK
                     DFNDQVELAKARAEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQ
                     EAKRIGLDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVE
                     ALSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQ
                     AGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDVTFPVAL
                     VNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSETYQTNNVFIRFGTN
                     YGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQDERVSAVESNFKQRADSLDAGVSRLT
                     EGLRTKVDISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNAT
                     KDKASKSELTQTAEELASKIASVHLGRRNLLKGTKELARYKPVSEYNGFKVIRTVAGA
                     TRYQDSYVERTVIPTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSENSSGYKSRS
                     SDGLSIIRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICAPAIFEG
                     NLAGDWSPAYEDQDERVSVVESNFKQRADSLDAGVSRLTEGLRTKADISSLNVTAENI
                     RQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVTEAGKLREE
                     FSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNIEPDFSSRLY
                     QKVTFSAWVKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADW
                     KYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDAD
                     GLITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESTRQAIAVRELVN
                     RDFVGKATYQEDVKGIN"
BASE COUNT         1025 a          668 c          820 g          804 t
ORIGIN      
        1 ttcttgcatg gcttgaccaa gagtgagatt gagtatcaga tatctggtat cacttgtaag
       61 acggacaaga agtctctgac ggtcggtatg aagacaggtc ggtctttgga actggacaat
      121 gtcttcatga cccagagcgc tttaaatgac ctgtattaca aactgaaaaa cctaacttac
      181 tatccgtata atctcaacta ccaaggacat ttgttacttg aggttgggca gtgggtaacc
      241 attcagacca acaagaaaga gacttttaaa gttcccgtgt taagtcagag ctttaccttt
      301 aaaggtggtc tgagaggtcg tatcagtgca gatagtaagg ctagaaacga tacccagtat
      361 tcttacgagg gtacgattac caagcagatt aagcaacaag atggcattga agcgaaaatc
      421 caagcgcaga ttgaagcagc agataaagat tttgaccaaa aggtcgacaa aatcaaaaaa
      481 gactttaacg atcaagtaga actggccaaa gccagagctg aagaagtcaa gagagaactg
      541 tctgacacta tcaatcagcg ctttaatagc tttgacaacg ggccattgaa agaaactaag
      601 cgcaaggctg aggaagcttt gcgaaatgct ggcgcaagta ccctgcttgc acaggaagct
      661 aagcggattg ggctggattc tgtcgctaga cttgaagcgt ttaagtcgca gactacgagc
      721 gcacaaacgg ctctgtcggg tgacttggac gctctgaaac gaactatcgc aaacgatatt
      781 cgaccgaagc aagcacaggc tgaagctgag attgccaagc aagttgaagc acttagccgg
      841 actaaaaatg aactggctgg cgtgaagtca gcgcaagcga cgtatgagga gacgacgact
      901 cgtagactgt cagaactgac caacttggcc aatggtaaag ccagcaagtc agaactcacg
      961 caaacagctg aggagctggc tagtcggatt gcgagtgtgc aggcaggtag ttcacggaat
     1021 tacttcagaa attcacgttc aagaacgttc acaacaggag gtcaagcggt atacgactat
     1081 cgaacattca tagttcctga tttctggaag aacagtgaca ggttcaagcg tgattatgtt
     1141 cgcatatctt ttgatgtgac tttccctgtc gccctagtaa atgacatgcc tgctatggtg
     1201 cattttagtg ctcatccatg gtatgcctac agaaacttaa tttttaaagg tggaactgtc
     1261 gaacgccaac attttgagtt tacgattgac ttgtctagtt cttctgagac ctatcagact
     1321 aataatgtgt tcattcgttt tggcactaat tatggatttc ctgctggtct gcaggtcgtc
     1381 attgagaacg ctatgttatc ggttggtaat tattttccag cctatcaacc agcgtacgaa
     1441 gaccaagacg aacgtgtctc agcggtcgaa tccaacttta aacagcgtgc tgattcactt
     1501 gacgctggtg taagccgtct gactgaaggc cttagaacca aagtggatat cagctcactc
     1561 aatgtgactg ctgaaaatat ccggcaatct gtgaagagtc ttgagacaga cacgcagaac
     1621 aaactaaatc agaagttgag tcaggctgaa tttgaggtgc gagctggctc tatccgtcag
     1681 gaaatcctga acgcaaccaa agataaagcc agcaagtcag aactcacgca gacagctgag
     1741 gagctagcta gtaagatagc gagtgtgcac ttagggcgca gaaatctgct gaaaggcaca
     1801 aaagagcttg cgagatacaa gccggttagt gaatataatg gttttaaagt tatcagaaca
     1861 gtcgcaggag caactagata tcaggatagc tatgtggaaa gaaccgttat accaacggct
     1921 gggacagagt atatagctat cttttatgca cgagccagtg aaaatgacta tcctgtgcgc
     1981 tgtcattttt acaatcctaa cacggttgta tcatcagaaa acagcagcgg atataagtca
     2041 aggtcgtcag atggcttgtc tattatccgt ctctcgacag actggcagtt gtgctgggtt
     2101 aaatggaccc aaaccgcaac agatcaagcc aagacggtca tcattggccg ccatggccct
     2161 caagtaggcg gtaaagaggg ggtatgggtt gaaatctgcg cccctgccat ttttgaggga
     2221 aatcttgcag gtgactggtc accagcatac gaagaccaag acgaacgtgt ctcagtagtc
     2281 gaatccaact ttaagcagcg tgctgattca cttgacgctg gtgtaagccg tctgactgaa
     2341 ggccttagaa ccaaagccga tatcagctca ctcaatgtga ctgctgaaaa tatccggcaa
     2401 tctgtgaaga gtcttgagac agacacgcag aacaaactaa atcagaagtt gagtcaggct
     2461 gaatttgagg tgcgagctgg ctctatccgt caggaaatcc tgaacgcaac caaggataaa
     2521 gcagataaga ctcttgtcgt gactgaagct gggaaattgc gagaagaatt ttcaaaaatg
     2581 aaggtgggag gccggaatct atggataaaa tccaagacgg ttggagctgt aattgaaaaa
     2641 ttacctgaaa accacgtcac aggtcaaaaa gaatgctata ggctagagaa caactctact
     2701 ttaacgttca acattgaacc agatttcagc tcaaggttgt atcaaaaagt tacttttagc
     2761 gcttgggtca agtacgaaaa tgtagtccaa ggtcgaaatt tttggaatgt atttaattgc
     2821 ttcaaacatt atctttttag aaaaaatagt gagaccggag tacagagtgg tccagattat
     2881 gctacgcttg gtatgtataa aggttcggca gattggaaat atattacatt cacttatgac
     2941 tactctgaaa aaacaaattt tgatcaattg aagacatcat tgcgattcaa tcttgaaggt
     3001 gctacaagcg gtacagcttg ggtaacagga atcaaggttg aaatcggtag tgtggcgacg
     3061 gactggagtc ctgcgcctga ggacgctgat ggtctcatca ctgaagctaa ggctaccttt
     3121 gagcggacag ctcagggctt gcgaaccgat ttatcagcta ttcaggaata tgtaaataaa
     3181 gacggtcagc gacaggaagc cctacagcgc tatactcgtg aggagagcac gagacaagcg
     3241 atagcagtcc gtgagctggt caatcgtgat ttcgttggta aggctactta tcaagaagat
     3301 gttaagggta tcaatca
//
LOCUS       DAVKZI010000095         3296 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKZI010000095 DAVKZI010000000
VERSION     DAVKZI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3296
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.096"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1249..1752
                     /locus_tag="VXB18_002169"
     CDS             1249..1752
                     /locus_tag="VXB18_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383289.1"
                     /translation="MKLLDCILDYQERFNRKACQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFIGDIFYFKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            2038..>3296
                     /locus_tag="VXB18_002170"
     CDS             2038..>3296
                     /locus_tag="VXB18_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV0383290.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEESPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEEKAAREEETAKKVNDAA
                     LAQQKAYAEYIKANQEQGRVRKEKLAEAQRKIDEATKKLEEAKVKLEEAEKKATEAKQ
                     KVDAEKYALEAKIAELEYEVQRLEKEIKEIDESDSEDYLKEGLRAPLQSELDTKKAKL
                     SKLEELSDKIDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAEKDLDAKKTELEKTEA
                     DLKKVANEPETPAPAPKPETPAPAPEAPAPAPAPKPEQPAPAPKPEQPAPAPKPEKSA
                     DQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPAPAPKPEQPAPAPKTGWKQENGMWYF
                     YNTDGSMATGWLQNNGSWYYLNSNGAMA"
BASE COUNT         1194 a          508 c          657 g          937 t
ORIGIN      
        1 tcttttagtg attcaaaaag caggctattt gttttcggtt ttacttcttt tttctaattt
       61 ttcagttcca tttatcaaag aaaaggaatt cgaattattt aaaaatagca agtaatagaa
      121 acataggtta aatcttagaa cggcttaaaa tcagatatga taaagggaaa tagtcttatc
      181 taggtaacta agtgctacaa acacagtcga ggatcacttg ttaggattac attttaatca
      241 tgcttaataa gaatggagaa ttcctatggg gattgtatta ctctgaagtt tcgaatacct
      301 tagttctcgt gattttgagc tattctaggt ttagaatcct tcagaatgta aaattttaag
      361 cagtcaaaga cttagaatag cccgaaaaca tttattttat agcaattcta ggcttagaat
      421 tgctcatata tatgtatttg agctgctcga tagttaggac agctttattc tgagaaatct
      481 gagctatcaa tgcttcagaa tagtatttcg ccaatggttt ttattgaaga ggtgattgtt
      541 ttatgatagt ctaaaataaa actgatttat ggagtaaatg gagaatcgtt acatgaaaca
      601 tttttttgca ggaattggtg agataaaact tgttggctac ttattgtata tatgtgtagg
      661 actagcccct ctttttcata tatatgtcat aggttcggaa ctgagttttg tgaaaatagt
      721 gttatctatt ttaggagtta tatttgtaag tatgttaact attgctcgaa tttatcggac
      781 ttttctataa agaatagttt ggacttgaac tgtatctaaa aacagaggtt ggtcgattat
      841 cagcctcttt cttgtcgttg aaaagagtga gatatattga cttttgaaaa aaagatgtca
      901 taattgagtt gggataaacc taaaagtaat atagtagatt gaatctggaa tagtccgtta
      961 tgactgttaa aatatttcta gaaattaatt tgactttcct aatcgatttg ttcacatctt
     1021 gtttcaatct actatacttt ctcgttaaac cgttcggcaa ttcatggtga catggacaca
     1081 tagtagtaag cacactatgt ggcttggcag agctaaaaac tgttcccttg tgataagcct
     1141 aataagcaca acatagggag ttagagaagc cgactctaat caaccacttt gggcagtagt
     1201 gagaactgcc ccgtgctttt ttattttgag aaaatatgga gtttgtcgtt gaaattactt
     1261 gattgtattt tggattatca agaaagattc aatagaaaag catgtcaagt atcaacgaat
     1321 tataagtatt tagagacttt caaagtgaat ttttgcctga ctgatttaca tcatttattt
     1381 ggcttacaca aaatcacacg agattatgct agtcaaacaa aacctgctat tcaagctggt
     1441 gtttttattt tagaagattt tagaaatatc ctattgtaca atgatgtaat cgaaaggata
     1501 tctttatatg agtttatagg tgatattttc tattttaaaa taacaagttg ttgcatcgta
     1561 gctaaggatt tatctaaaaa tactatgaaa ttggacgtca tattttttga ggataaaaat
     1621 aaaagatccg cagttttagg tttacgaaga gacaaaagcg gagtatttaa accagttact
     1681 ctacatttta caagcgctaa gaaatatgct aaagttcgta aaacagatgt gaaagaaatg
     1741 aaatggctat aaagattgtc cgcaggctta agcttgcgtt ttttgttgtt taacgaaatt
     1801 aaaaaacaag ctctctcatc ggaagtgttt ttataggaat gaaggaagat gatgctatgt
     1861 ttaaaaagag aatcgaaaag ggcaaaagta gtgtctttat ctttttggag tagaagctta
     1921 tgatatagaa atttgtaata aaaatgtaat ataaaacatt tgacaaatat ttacgggggg
     1981 agtatactta atataagtat agtctaaaaa tgactatcag aaaagaggta aatttagatg
     2041 aataagaaaa aaatgatttt aacaagtcta gccagcgtcg ctatcttagg ggctggtttt
     2101 gttgcgtctc agcctacttt tgtaagagca gaagaatctc ccgtagctag tcagtctaaa
     2161 gctgagaaag actatgatgc agcgaagaaa gatgctaaga atgcgaaaaa agcagtagaa
     2221 gatgctcaaa aggctttaga tgatgcaaaa gctgctcaga aaaaatatga cgaggatcag
     2281 aagaaaactg aggagaaagc cgcgcgagaa gaagaaactg ctaagaaggt aaacgatgct
     2341 gctttagcgc aacaaaaagc atatgcagaa tatataaaag ctaatcagga acaaggtagg
     2401 gtccgtaagg aaaaattagc agaggcgcaa agaaaaatag atgaagcgac taaaaaacta
     2461 gaagaagcta aagtaaaatt agaagaagct gagaaaaaag ctactgaagc caaacaaaaa
     2521 gtggatgcag aaaaatatgc tcttgaagct aaaatcgctg agttggaata tgaagttcag
     2581 agactagaaa aagagatcaa agagattgat gagtctgact cagaagatta tcttaaagaa
     2641 ggcctccgtg ctcctcttca atctgaattg gataccaaaa aagctaaact atcaaaactt
     2701 gaagagttga gtgataagat tgatgagtta gacgctgaaa ttgcaaaact tgaaaaagat
     2761 gtagaagatt tcaaaaactc agacggtgag caagctgaac aatatcttgt tgcagctgaa
     2821 aaagacttag atgctaaaaa aactgaatta gaaaaaactg aagcggacct taagaaagta
     2881 gctaatgagc cagaaactcc agccccagct cctaaaccag aaactccagc cccagctcca
     2941 gaagctccgg ctccagctcc tgcaccaaaa ccagagcaac cagctcctgc accaaaacca
     3001 gagcaaccag ctccagcacc aaaaccagag aagtcagcag atcaacaagc tgaagaagac
     3061 tatgctcgta gatcagaaga agaatataac cgcttgactc aacagcaacc gccaaaagca
     3121 gaaaaaccag ctccagctcc tgcaccaaaa ccagagcaac cagctcccgc accaaaaacg
     3181 ggctggaaac aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggctaca
     3241 ggttggctac aaaacaacgg ttcatggtac tacctcaaca gcaatggcgc tatggc
//
LOCUS       DAVKZI010000096         3138 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKZI010000096 DAVKZI010000000
VERSION     DAVKZI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.097"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            270..1556
                     /locus_tag="VXB18_002171"
     CDS             270..1556
                     /locus_tag="VXB18_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0383291.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1571..1882
                     /locus_tag="VXB18_002172"
     CDS             1571..1882
                     /locus_tag="VXB18_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383292.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2128..2856
                     /locus_tag="VXB18_002173"
                     /pseudo
     CDS             2128..2856
                     /locus_tag="VXB18_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
BASE COUNT          979 a          538 c          680 g          941 t
ORIGIN      
        1 attataggag caacagagtg ggagtagtca tctaaggact aatttatata tttttacgag
       61 tcagtatctt gggatactgg tttttacttt tttagacttt ttgactactt gttaaaactg
      121 gggtaatttt cgactgttta atagttatta tgcaaagtct aaaagattag aattgtcaaa
      181 acaatccgtc taggcttgat tttatccttt atttactata aaatgagaag gaaaaatgtc
      241 aaacttttat attgcaaata ggagaaatta tgacaaaaac attaaaacgt cctgaggttt
      301 tatcacctgc agggacttta gagaagctaa aggtagctgt tcagtatgga gcagatgctg
      361 tctttatcgg tggtcaggcc tatggtcttc gtagccgtgc gggaaacttt actttcgaac
      421 agatggaaga aggcgtgcag tttgcggcca agtatggtgc caaggtctat gtagcggcta
      481 atatggttat gcacgaagga aatgaagctg gtgctggtga gtggttccgt aaactgcgtg
      541 atatcgggat tgcagcagtt atcgtatctg acccagcctt gattatgatt gcagcgactg
      601 aagcaccagg ccttgaaatc cacctttcta cccaagccag tgccactaac tatgaaaccc
      661 ttgagttctg gaaagagcta ggcttgactc gtgtcgtttt agcgcgtgag gtttcaatgg
      721 aagaattagc tgaaatccgc aaacgtacag atgttgaaat tgaagccttt gtccatggag
      781 ctatgtgtat ttcatactct ggacgttgta ctctttcaaa ccacatgagt atgcgtgatg
      841 ccaaccgtgg tggatgttct cagtcatgcc gttggaaata cgacctttac gatatgccat
      901 ttgggaaaga acgtaagagt ttgcagggtg agattccaga agaattttca atgtcagccg
      961 ttgacatgtc tatgattgac cacattccag atatgattga aaatggtgtg gacagtctaa
     1021 aaatcgaagg acgtatgaag tctattcact acgtatcaac agtaaccaac tgctacaagg
     1081 cggctgtgga tgcctatctt gaaagttctg aaaagtttga agctatcaaa caagacttag
     1141 tggacgagat gtggaaggtt gcccaacgtg aattggcaac aggtttctac tacggtatac
     1201 catctgaaaa tgagcagttg tttggtgctc gccgtaaaat ccctgagtac aagtttgtcg
     1261 ctgaagtggt ttcttatgat gatgcggcac aaacagcaac aattcgtcaa cgaaatgtca
     1321 ttaacgaagg ggaccaagtt gagttttatg gtccaggttt ccgtcatttt gaaacctata
     1381 ttgaagattt gcatgatgcc aaaggcaata aaatcgaccg cgctccaaat ccaatggaac
     1441 tattgactat taaggtgcct caacccgttc aatcaggaga catggttcgt gcattaaaag
     1501 aaggactcat caatctttat aaggaagatg gaaccagcgt cacagttcga gcttaagaaa
     1561 ggaaaaggaa atgatagagg cacagggttt cttagtggat aagcaaacaa gatgcattca
     1621 ttaccatagc aagctggata ttattgcttt acaatgctat gattgtaaaa agtattatgc
     1681 ttgttatcgg tgtcatgatt cattagaaaa tcaccctttt gagccgtatc ccttatcttt
     1741 gatacaggat aagcctattt tatgtggtgt ttgtctaaaa ctactaacat ataagcaata
     1801 taaagaaagc ttaagttgcc ccttttgttt ttctcgcttt aatccaggtt gccaaaatca
     1861 taaggaacgc tattttaaat agcaaatcat ctagttttga agtaggagaa aactcaattc
     1921 caagagaaaa tgaagtaaat cttcccacaa taaaacgcat aatatcaaga ttgttcaata
     1981 cctgatacta tgcgttttta agattttaaa gacttttttc ctttatctgg tattttgact
     2041 acttgttaaa accgggttaa ttttcaactg tttaacagtt attatgcaaa gtctaaaagg
     2101 ttagaattgt caaaacaatc cgtctagagt atgcgtgatg ccaaccgtgg tggatgttct
     2161 cagtcatgcc gttggaagta cgacctttac gatatgccat ttgggaaaga acgtaagagt
     2221 ttgcagggtg agattccaga agaattttca atgtcagccg ttgatatgtc tatgattgac
     2281 catatctcag atatgattga aaatggtgtg gacagtctaa aaatcgaagg acgtatggag
     2341 tctattcact atgtatcaac agtaaccaac tgctacaagg cggctgtgga tgcctatctt
     2401 gaaagtcctg aaaagtttga agctatcaaa caagacttgg tggacgagat gtggaaggtt
     2461 gcccaacgtg aactggctac aggattttac tatggtacac catctgaaaa tgagcagttg
     2521 tttggtgctc gtcgtaaaat ccctgagtac aagtttgtcg ctgaagtggt ttcttatgat
     2581 gatgcggcac aaacagcaac tattcgtcaa cgaaacgtca ttaacgaagg ggaccaagtt
     2641 gagttttatg gtccaggttt ccgtcatttt gaaacctata ttgaagattt gcatgatgct
     2701 aaaggcaata aaatcgaccg cgctccaaat ccaatggaac tattgactat taaagtccca
     2761 caacctgttc aatcaggaga catggttcga gctcttaaag aggggcttat caatctttat
     2821 aaggaagatg gaaccagcgt cacagttcgt gcttaatgta gttgtttagt tttaaaaaac
     2881 tatgcaaagc tccatataca acacttaaac gagattaaag aatggcgaaa tcccttgatg
     2941 cgcaagagat tagctgtctt ttttattttt taagtgataa agtcggagtt taggcatcaa
     3001 agcctatcaa attaaacaaa gaagcgatgt cttagatatt ttgaaaaaaa ttaataagca
     3061 gaaaactctc tattattttg ttgtagagag ttttttgtta ataaaatttc acaaaatgac
     3121 atttatatat tgcattaa
//
LOCUS       DAVKZI010000097         3075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKZI010000097 DAVKZI010000000
VERSION     DAVKZI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.098"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(152..2653)
                     /locus_tag="VXB18_002174"
     CDS             complement(152..2653)
                     /locus_tag="VXB18_002174"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0383293.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT          842 a          680 c          613 g          940 t
ORIGIN      
        1 tatatatcat actttcataa gaaggttcaa aaaatcctcc agattctact ctgaaggatt
       61 cctatcttat ttcacaacaa tgttaactaa tttagttggc ttcaatagtc cagtggacta
      121 ttgaaggtgg cagatagagc taataaactc gttatttaac gacgatatta acgagtttat
      181 tcggtaccgc aattactttc acgatttcct taccgtcaat ttctgctttg actttttcat
      241 cagctaaagc gatttcttgt aattcttcac gtgatatatc tttagcaacc atgagtttgg
      301 cacggacttt tcctttgatt tggacgacaa tttcaatttc atcttcaacc aatttgcttt
      361 cgtcccaagt tggccaagct acataagaga ttgactcacc tgtttctgcg actgtttgcc
      421 agagttcttc tgccaagtga ggtgcaaatg gtgcaatcaa ttgaataaag cctttggcat
      481 agtcaacata aagcttatct tccttgttag cagcattgac aaagaccata agttgggcaa
      541 tagctgtgtt gaatttgaga gactcaattt gctcagtaac agctttgact gtttcgttgt
      601 aaaccttgtc aagagcacca ttgttttccg caaggatttc tttacttgta atcaaacggt
      661 aaactcggtc aaggaactta cggcttcctt ccaaaccttc ttctgaccaa gcaatcgaag
      721 catcgagtgg tcccataaac atttcataaa cacgaagggt atcggcaccg tattgttcca
      781 ccacatcgtc tgggttaaca acgttcttga gcgatttaga catcttggct ggcgcttgct
      841 ccaactcttc ccctgtttct acatgaaaga aggaaccatc acgtttttca accttgtcgg
      901 ttgccacaag agcaccacgg tggtcacggt agcttgttcc caaaatcatc ccttggttaa
      961 agagtttttg gaatggttcc ttagtcggaa caacaccgag gtcatagagg aatttgtgcc
     1021 agaaacgagc gtaaagcaag tgaagtacag catgttccgc accacccacg tagatatcta
     1081 ctggcaacca ttgtttgagg aggtcctcat cagccaattt ctcagtattg tgtggatcaa
     1141 tatagcggag gtagtaccaa cttgaaccag cccattgtgg catagtgttg gtttcacgac
     1201 gacctttgac accatcttca cgagtcactt caagccaatc tgtcaagtta gctagtggac
     1261 tttcaccagt acctgaagga cggatatcct tggttacagg caagacaagc ggcaattcag
     1321 tttcaggaac agctgttgaa gttccatctt cccaatgaat gattggaatt ggctcacccc
     1381 agtaacgttg acggctaaag agccagtcgc ggagacggta ggtaaccttc tcctgaccac
     1441 agcctttttc ttccaaccaa gccacaatct tggcaatagc gtcttctttg ttgagttcat
     1501 ctaggaagtc tgaattgaca tgcaggccat cctctgtgta ggcagcttct ttgacatctc
     1561 caccttcaag tacttcgacg attggaaggt caaattgttt ggcaaattcc cagtcacgtt
     1621 ggtcgtgggc aggcacagcc ataaccgcac ctgttccata actagcaaga acatagtccg
     1681 caatccagat tggcatttcc ttaccattga cagggttgat ggcataggca cctgtccaaa
     1741 caccagtttt ttccttagca aggtctgtac gagccaagtc agacttaagg ctggcttggt
     1801 gtttatagtc tgctacagct tctgcttgct ctgaacttgt gatagcgtct actaattcat
     1861 gttcaggagc caagacagtg aaagtcgcac cgaaaagtgt gtctggacga gtagtaaaga
     1921 ctgtaaattc cttgtctgtt ccttttactt tgaaagttac attggcacca gttgatttac
     1981 caatccagtt gcgttgcata tccttgatag actctgacca atctagttca tctaagtcat
     2041 tgagcaagcg ctctgcgtaa gccgtgattt tgagcatcca ttggcgcatt ggtttgcgga
     2101 caactggata gcctccacgc tcagaagttc cgtcaggaag cacttcttca ttggcaatgg
     2161 cagttcccaa ttcctcaacc cagtttactg gcacttcagc ttcataggcc aagccttttt
     2221 cgtaaagctt ggtgaaaatc cattgagtcc acttgtagta gtttggatct gttgtgttga
     2281 cttcacgatc ccagtcataa gaaaatccaa gcgcattgat ttgacgtttg aagttggcaa
     2341 tgttttccgc tgtaaattct gctgggtcat taccagtatc catagcgtat tgctctgcag
     2401 gtaaaccaaa agcatcccaa cccattgggt gaaggacatt gtagccttgc gcacgtttgt
     2461 aacgactgag gatatcggtt gcagtataac cttctgggtg tcctacatgc agaccagctc
     2521 cagacggata agggaacata tcaagcgcat aaaacttagg ttttgatgca tctgttcctg
     2581 tcttaaatgt atgatgttct gcccagtagc cctgccactt aggctcaatt tctttatgat
     2641 tataaaaact catggtctct ctccaatttt gtgatgttac tattatacca tttttgaggg
     2701 aatttgaaat gtgtttaaag aaaaaactgt atactgtatc tcattaattt tgatgactat
     2761 gaattgctct atctcccact ttttatccca ttgttatgca gtaaatcaag gagtaagtca
     2821 agaagcttat ctcgtatagc acaaaatact tactttagac cgaagataaa actggaatgc
     2881 taattaatgt attcacaata aatagccgac aacctatgtc gctttttgat ttatgaagaa
     2941 cgtatagtgg actgaatctg aaatagtacg aaacaattgc taaaacactt atagaaatta
     3001 attttacttt cccaatcgat ttgttctcat cttatttcaa tctgctatag aattcaatac
     3061 gaggatcaat aaaag
//
LOCUS       DAVKZI010000098         2941 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKZI010000098 DAVKZI010000000
VERSION     DAVKZI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.099"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(116..2374)
                     /locus_tag="VXB18_002175"
     CDS             complement(116..2374)
                     /locus_tag="VXB18_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0383294.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLKEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KKKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2603..2833)
                     /locus_tag="VXB18_002176"
     CDS             complement(2603..2833)
                     /locus_tag="VXB18_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0383295.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
BASE COUNT          791 a          604 c          610 g          936 t
ORIGIN      
        1 agattcagtc tactatatat cataatggac aaagggcaag ctgtcaagaa attacagtta
       61 ttttagtaaa aaaagaagca gaaaaatttc attttctact ccttttctat aggatttatt
      121 tttctttttc agaactttta acttcagctt ttttggcaga tttaatctga atgtttccct
      181 tgctagtcat aactgctttg agatcttttt cgcttggatt ttcaaggtag tagtcagtga
      241 ttgtgtcctc aatatagtct tgaatagtcc gacgaagtgg gcgtgctccc atttttggat
      301 cataacctag gtcaaccaac tttttcttga ccttatcagt tacatccaaa cgaatgttgt
      361 tgctagagag gcgcttgtta acatctgcta gcatgagctc gacaatctga aggaggttat
      421 ccttgctgag agccttaaat tcgataatgc catcaaaacg gttcataaac tctgggctaa
      481 agaagttacc gagttcaccg aggacagaat tggtacgtcc ttctctagca gcaccaaatc
      541 caacgctagc ttcggtcttt cctgtacctg catttgaggt catgataatg atggcatcct
      601 tgaagctaac ggtgcgtcct tgcccgtctg tcaaacgacc atcgtccaag acttgaagaa
      661 acatgtgcat aacatctggg tgagcttttt ccacttcatc gagaaggatg agagaatatg
      721 gattgtggcg aactttttca gttaattgac cagcctcatc atagccaaca taacctggag
      781 gggcgccgac caacttagcc acactatgtt tttccatgta ttcactcata tcaaagcgaa
      841 tcatactatc agcagaacca aaaagttcga tagccagttg tttggaaagt tctgtcttac
      901 cgacaccagt tggcccaacg aagaggaagc ttccgattgg gcggttaggg gtaccaagtc
      961 cgacacgatt acggcgaata gccttggcaa tcttatcgac tgcatcatct tggccaataa
     1021 catgagactt gagatcttcg gctagatgga tgagttgaga ttgttctttc tctttcaaat
     1081 caccaacagg gatattggtt ttctgctcga taatgtgctc aatagttttc tcgctgatga
     1141 taggagtatc ctggtctgtg atctttttct tttgcatttc cttatacttg gcaatctggt
     1201 cgcggaagta ggccgccttc tcaaaatctt cttctcgtgt agcttgagac ttgagatttt
     1261 cagcctcaat caagcgctga tcaattactt taggatccac aaaattcaag gtcaagttca
     1321 tcttagaacc agcttcatct aggaggtcaa tggccttgtc aggcaagaag cgatcttgga
     1381 tgtagcgatt ggaaagagtt gcagctgctt caatcgcagc atctgtatat tgaacgtggt
     1441 ggtaatcttc gtatttcttt tgaatccctt tgagaatagt gattgtttcg tccaccgttg
     1501 gttcatcgac tttaacaggc tgcatacgac gctcgagggc agcatccttt tcaatgatac
     1561 ggtattcatt gagggtagta gcaccgacta gttgcagttc tccacgagca agggctggct
     1621 tgaggatatt tcctgcgtcc atattaccat cactcgcaga accagcacca acaatttcat
     1681 ggatttcatc gataaagagg atgatgtctt cacgtttgcg aatttcttcc atgagttttt
     1741 gcatgcgttc ttcaaattgt cctcgaatcc ccgttccttg aactaagcta accacatcca
     1801 gacggatgac ttgtttacct tggagtttat gtggcacatc gccatcgaca attttctgag
     1861 ctagaccttc gacaacggcc gtttttccga caccaggttc accgataagg acaggattat
     1921 tcttggttct acgattgaga atctcgatga cacggataat ctcatcgtcg cgcccaataa
     1981 cggggtcaat gtctccacga cgggcaattt cagttacatt aataccaaat tctttcagca
     2041 ggcctttttc ttggctaggt ggcggagttt gagcagatcc acgattttgg gaaccataac
     2101 cgccgtttcc accgtaacct ccacctgatt gggttggggg aataggagga gtattgctag
     2161 aaggtctgaa attgtttaga tcattgaaga aatcaccaaa gggatcgaag tcacgattgt
     2221 tcagatccgt catacctttg aagaggctat tgttaggatc tgttttgata atcttatagc
     2281 agttttgaca gaggtcaatt tgtttttgtt ttccattgag attggtgtaa agatgaattg
     2341 ttgagtcgtt aattttacag ttttgacaaa gcatacatct acctcatttc tttctttagc
     2401 ctgacttgtt taaaggtcaa aaatagtcaa attctatact ctcattataa caggattggg
     2461 gtgtaaagca agtaaaaaga ttgaagcttt gagaagttgt tacaatgaaa atttttgtga
     2521 atttggacta taaaaaaatc ctatttgtga gacaaaaagg attttactta gacatgcagg
     2581 gacaatccca gcttgtttta gattagtaga gaagttcgta aatttccatt gcgattaagt
     2641 caatgctatc aaacgtatac gtttcgcgat cttctacgtc acgaagggta aagattgggc
     2701 cgttttcttc gtcgtggctg tacgcaactt ctgcaacaac aactccttcg cgttcaaaat
     2761 tacgttttaa atttccgcca tcgtttgcca ttgcttcaag gcggttgatg attctaacca
     2821 aatgtgattc cattttgatt ctccttcatt tcttatcgtt actattttac cataaaggag
     2881 gccaacttga ctagaaaaaa ctaagatttc tcgctaattc tgctagttta aaggttttta
     2941 a
//
LOCUS       DAVKZI010000099         2908 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKZI010000099 DAVKZI010000000
VERSION     DAVKZI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.100"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(60..374)
                     /locus_tag="VXB18_002177"
     CDS             complement(60..374)
                     /locus_tag="VXB18_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0383296.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(504..743)
                     /locus_tag="VXB18_002178"
     CDS             complement(504..743)
                     /locus_tag="VXB18_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV0383297.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(795..2231)
                     /locus_tag="VXB18_002179"
     CDS             complement(795..2231)
                     /locus_tag="VXB18_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0383298.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFAAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVTADGMVHD
                     DYRIEYLDAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(2421..2759)
                     /locus_tag="VXB18_002180"
     CDS             complement(2421..2759)
                     /locus_tag="VXB18_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0383299.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT          964 a          604 c          358 g          982 t
ORIGIN      
        1 atatcaaact caaaacaatt tatcttaact taaatattta ttgacatttc atgtgttcat
       61 caaatattct caagaatcaa attagccatt ttttcaattc ccattggaat aggaatatag
      121 gcttgaggag gtatttgtac aactggtttt cctgctttag aaccagcctc ttcaaattgc
      181 ttaaagtaca tttttgtttg aggactgaca agatacaaat caaaagctgc tgctgcgata
      241 gctttccctc cttcagtagc actaatagca tcaactacaa tatctttccc ttttcctttt
      301 agaaactctg ttgttttctg tgccataagt gatgaagaca ttcctgctgc acaaataatt
      361 aaagcttttg ccataatatt ttctcctttt cttaaatcca atcaaagctg tgctaagttg
      421 gcttatttgt tatctatttt tattataaaa taaagcgttt ccaatgacaa ttccctcatt
      481 ttcctaaatg atatggaaaa aaattattta tacttcaatt tataaaataa aattattcct
      541 gagagtagaa atgaaacact atttgctaaa atcaaaggca agtctcctat acgaatacca
      601 tgagcaagcc acaatgcaat accaataact tgcataacat acatacctag agcaatagag
      661 cctgtgtcct ttgtcttaac tacacgaaaa acttgtggta aaaatgcaaa tgttgttaaa
      721 attgctgcaa tacttccaat catatgtcac ctcaatatgc taaacaaact gagaataatc
      781 tcagtttgtt tatactattc tactgattca ccgttagatg aaataacttc cttataccag
      841 ccaaaagatt ttttcgggga acgattataa cttcccttcc cattatcatc tttatctaca
      901 taaataaagc cataacgttt ccgcatttca ccggtaccag ctgaaaccaa atcaatacat
      961 ccccatggag tataacccat taaatcaaca ccatcttcaa ctacagcctt tttcatttca
     1021 cgaatatggg catctagata ttcaattcta taatcatcat gtaccatacc atctgctgta
     1081 acttgatcta tagctccaaa accattttca acaataaaga gtggtaagtg atagtggtct
     1141 gtaaaccaat ttaacgcata acgcaaacct tctggatcaa tttgccactc ccattcagaa
     1201 gccttaacat aattattttt cactaaatct tctgtttcaa gataatcaaa ataaggatta
     1261 ttttcacgat gagagtcgat agcaaaggac atatagtaac tgaaaccaat gtaatctaca
     1321 gtcccaccaa gtaaatcttc tttatcctgg gcagcaaaat caactgaaat accttttcgt
     1381 tcccaatact tgaaaatatg ctcaggatat ttacctaaaa catgcacatc agcaaaataa
     1441 taacgcttct gcatagcttt cattgccatt aagatatcct taggattgca agtagctgga
     1501 taaattggac acatcgcaat catacaacct atttgaaaat ctggattaat ctcatgacca
     1561 atttttacag ctcgtgcaga agcaactaat tcgtaatgtg ctgcttgata cataattgct
     1621 tctctattat caccttcctc atatacaata cctgagttag taaatggtgc aaaatcttcc
     1681 tgataattcg cttgattatt gatttcattg aaagtcatcc aatatttaac cttatctttg
     1741 taacgtttaa atacgacttc tgcaaaacga gcaaagaaat caatcaattt cctatttttc
     1801 caaccaccat attcggtcac taagtgataa ggcatttcaa aatgagatag agtgatgaca
     1861 ggttcaatac cattctttaa gcattcatca aaaagattat cataaaactg taatccttct
     1921 tcattcggct ctaactcatc accttttgga aagatacgcg tccatgcaat agaggtacgg
     1981 aagcacttga atcccatttc agcaaaaagt gctatgtctt ctttataacg atgataaaaa
     2041 tctatcgcct catgatttgg ataatattta ccctctaaaa ctcccgaagt aatttcacga
     2101 gctactccat gacgaccagc agtcataaca tcagcaacac taattccttt gccaccttct
     2161 tgccatccgc cttcaagttg atgagcagca acagcaccac cccataaaaa tctatcttta
     2221 aaagtagtca tcttttttcc tcctgacttt gatactctta ttataaacct taaaccaaaa
     2281 tatgaaaacg cattcttttt ccttattgtt aaggaaagaa gtaattttta atggaaatag
     2341 aacaatatct tcttgtattc tcgtaatgat atctttacga ttttcaatac tttcaaacta
     2401 caaaaactct cacaataatt ctaattccct gtgtctataa acgacttatc gctttctggc
     2461 atcccagaat catcttctat ataacgttca acttgcatct gcaagtgata tttttttctt
     2521 aaatctaaga ttttctgcat tgtctttgat tgatgatgtt catctaaagc ttcttgattt
     2581 atccactgat caataaggag aatagttccc tctttttcaa ttggtaaaaa atattcgtat
     2641 ttcaagttac ctttttgatt tctaatttct tcaacaaggc cactatcaag catttctctt
     2701 gcaaacttta ttgcactatc tccatcacct ttataatata catgaatagt caatgtcatc
     2761 ttatatcctc caaaatcatc cttcaatttt aaaaaaacaa gtttagatga ggatctaaac
     2821 ttgtttttta tgaactaatt atctaacgtt tcgccattac tttcaatcac ttctttatac
     2881 caataaaatg attttttctt atagcgat
//
LOCUS       DAVKZI010000100         2896 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKZI010000100 DAVKZI010000000
VERSION     DAVKZI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2896
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.101"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VXB18_002181"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VXB18_002181"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0383300.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1400..2176
                     /gene="recX"
                     /locus_tag="VXB18_002182"
     CDS             1400..2176
                     /gene="recX"
                     /locus_tag="VXB18_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0383301.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2265..2798
                     /locus_tag="VXB18_002183"
     CDS             2265..2798
                     /locus_tag="VXB18_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0383302.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT          923 a          529 c          527 g          917 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggtcttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttgggttt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 tggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atacccctat cttatcacat
     1381 tttgagttat aatagagcta tgaaaatcac aaaacttgaa aagaaaaaaa gactctatct
     1441 gatggagctt gataatggcg acaaatgcta tatcaccgaa gatacaattg ttcgttttat
     1501 gttatcgaga gataaggtga taagcgaaga ggaattgaaa gagattcaag actttgctca
     1561 attttcttat ggtaagaatc tggccctcta ccacttatcc tttaaagcac gcactgaaaa
     1621 agaagtcaga gaatatctga aaaaatacga tattgatgaa aacatcgttt ctcaagttat
     1681 tgctaatctt aaagaagata agtggattaa tgatggtcag tacgcttatg ctatcatcaa
     1741 taccaatcaa ctttcaggag acaagggtcc ttatgtgctg actcagaaac tagctcaaaa
     1801 agggatttca aaatctacta tagaagagaa cttgaaagaa tttgattttt ctgaagttgc
     1861 tcaacgtgta gctaataaac tattgaaaaa atatgaggga aaacttccag ctcgtgccct
     1921 gcaagataag attatccaga acttgactaa caagggcttc tcttattctg atgctaaaat
     1981 tgcctttgac gacttagata gccaagttga ccaagaaacg actcaagaac tcatcttcaa
     2041 ggaacttgat aagcaatata ctaagtatgc tcgaaagtat gaaggatacg aactgaagca
     2101 gcgtttaact caagttttag cacgaaaggg ctacgatttt tcggatatag caagcgctct
     2161 tagagaatat ctttaatatt tccaagtgaa attcacagat tttaggtaat tttatggtac
     2221 aatagtaaat gataaactta taaattgtag aaagttggtt agttatgaag cttccaaaag
     2281 aaggcgactt tattacaatt caaagttata agcatgatgg gagtctccac cgaacttggc
     2341 gggacaccat ggtactaaaa acaacagaaa acgccattat tggtgtcaac gatcatacac
     2401 ttgttaccga aagtgatggt cgtcgttggg tcactcgaga accggctatt gtttactttc
     2461 acaagaaata ttggtttaat atcattgcca tgattcgtga taatggaact tcttactatt
     2521 gcaatatggc tagcccctac tatctggatg aagaagcact gaagtatatt gattacgatt
     2581 tggatgttaa aatttttaca gatggggaaa aacgtctctt ggacgttgaa gagtacgagc
     2641 gtcacaaacg caaaatgaat tattctgatg acttggatta tattttaaaa gaacatgtca
     2701 aaattcttgt tgattggatt aacaatggac gtggtccttt ctcagaagcc tatgtaaaca
     2761 tttggtacaa gcgctatgta gaactaaaga atcggtaaag ttgtcaaagg tcaggaacaa
     2821 aatcctgacc tttttttggt agtataaaat aaattgtgta aacacaaaaa ggaataaatc
     2881 tattatagca gagtta
//
LOCUS       DAVKZI010000101         2811 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKZI010000101 DAVKZI010000000
VERSION     DAVKZI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.102"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(20..457)
                     /locus_tag="VXB18_002184"
     CDS             complement(20..457)
                     /locus_tag="VXB18_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0383303.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNEPAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(498..1505)
                     /locus_tag="VXB18_002185"
     CDS             complement(498..1505)
                     /locus_tag="VXB18_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000231692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0383304.1"
                     /translation="MVFNPLYTFWIDYVKFFYRPYYSCRKIFKEEDSINHRKASYINT
                     QDNNYNKHIKDYFSMVDNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILL
                     KKIFDVGLRKGYYSSNPAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFT
                     VLFFTGLRLGEALALTWQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINK
                     KLSQELQDWEKRQKHLLEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSILKK
                     IRIHDFRHSHASLLINQGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDL
                     L"
     gene            complement(1791..2558)
                     /locus_tag="VXB18_002186"
     CDS             complement(1791..2558)
                     /locus_tag="VXB18_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HEV0383305.1"
                     /translation="MTNTAKKLTILSANLNFYMSNKVQKKTSEKIVKMLLSEEQNPKP
                     TFIALQEVGNRVIYKVEKDEIEDYSVNIERIENKLFNEGYGVIRPKQYGKEKDASNPV
                     NTRLFYLKKSVESIKELTPLGLGIKEDFYNRQCGGIFTINNQTIAVYSLHFKWQKDER
                     GAFWKKYIEIAESNKYNHLILAGDFNESLINVTTELSDKITKMKNYMVDASHDLPTWK
                     DKQLDHIFITPNTKIENYSTLDNDFSDHKALQVTIIV"
BASE COUNT          810 a          446 c          420 g         1135 t
ORIGIN      
        1 aaattttata gtttagttac taactttttt tctttgctct taaaaatcta atagcagaac
       61 tgtatttctt atttctctct aagtcttttt cagtaattaa tggtagtctt gttaaatctg
      121 aattatgccg taaatccgcc aactttacaa ctctagcggg ttcatttttc tttactagat
      181 tgagataaga ttgataatct tgtccttttt tctttgtgag tatatcaacg gcttctataa
      241 tgttttttga aaaaccttcc ttttttaggt ctagtagggt tagtgaagta tcttcaatta
      301 catcatgtag ataggcgaca gctttctctt catcagttgc gacaaaacta gctactgttt
      361 cagggtgttt aatgtagtca attcctgctc tatcaatttg tccaaagtgt gcttttttag
      421 ctacttcatg tgcttttatt acttgtgatg tatccatgat ttaattataa actttccatt
      481 tataaaactc aattacttta tagtaaatca tctagtttat cagctaaatc cttttgctta
      541 cttgggtaca agtgagagta ggtatcaatc gtggttgtta tagaagcatg tcctagtcgc
      601 tcttttacaa ctagataatc ttccccttgg ttaatcagca gggaagcgtg tgagtgccta
      661 aaatcgtgta tgcgtatctt ttttagtatg ctatcacgtt caatgatttt cttgtactgc
      721 ttttcaatag cattttttgt aattgtgata ggactatttt gaaacacttg taatgttagg
      781 ctattgttgg taaattgctc taatagatgt ttttgtcgct tttcccaatc ttgtaattct
      841 tggcttaatt ttttattgat aacaattctt cttgttcctg ctttagtttt tgttgtgctg
      901 atatgagtta ctcctttatt aacatagaca gacttcgtga tatgaattgt attacttgaa
      961 aagtcgatgt cttgccatgt tagggcaaga gcttccccaa gtcttaatcc tgtaaagaat
     1021 agaacagtaa agagtagttt gatattgtat tcttcgggtt caaatagtgt caaaaacttc
     1081 tgaaattctt tgactgtcca aaattgcatt tttgtttttt caattggcaa cttttttatt
     1141 aattttgctg gattggagga gtaatagcct tttcgcaaac caacatcaaa aatttttttg
     1201 agtaaaatca tgattttgtt aatagtattt gtgcttaacg gtttatcaga atttttagct
     1261 actttttgcc taagatgttc tctaaattgg tagatgtctt cataggttag ttttccgaca
     1321 ttatcgacca tagaaaaata atctttgatg tgtttgttgt aattattatc ttgtgtattg
     1381 atatagcttg cttttcgatg atttatacta tcttcttcct taaaaatttt tctacaagaa
     1441 taataaggcc tgtaaaaaaa cttgacataa tcaatccaaa aggtataaag gggattgaaa
     1501 accaagtatt tatcaataag aggcccacta acaattcagt tcctattcta ctaagaaaaa
     1561 gtctacgaga agtaataaca tagggattaa cttttacttt cacagatttg ctcagtttca
     1621 gtattttcat cttcattcct ctcagaaatt aatgtatcta tacaaccaat taaaaagata
     1681 aatggatttt aataaggtca ggccctctaa tatttgcaat actagtaata atataagttt
     1741 tggttaaaac tgcaacggtt ctaattttaa ataatttcat ttcggaactc ctaaactata
     1801 atagtcacct gcaaagcttt gtggtcactg aaatcattat cgagagttga atagttttcg
     1861 attttggtat ttggtgtgat aaaaatgtga tcaagttgtt tatccttcca tgttggtaag
     1921 tcatgactgg catctaccat ataatttttc atttttgtta ttttgtcaga caattcagta
     1981 gttacattga ttaagctctc gttaaaatcg cccgccaaaa taagatgatt atacttgtta
     2041 gactcagcaa tttcaatata ttttttccaa aatgcacctc tttcatcttt ttgccatttg
     2101 aaatgaagag agtaaactgc aatagtttgg ttattgatag taaaaatacc accacattgt
     2161 ctattataga aatcttcttt tattcctaat cctaagggag ttaattcttt gatagattca
     2221 actgattttt ttaagtaaaa caatcgagta tttacaggat tgctcgcatc tttttctttt
     2281 ccatattgct tagggcgtat cactccgtat ccttcattaa atagtttatt ttctattcgt
     2341 tctatattca cactgtaatc ttcaatttca tctttttcta ctttataaat aacgcgatta
     2401 cccacctcct gcaatgctat aaaagttggt ttggggtttt gttcctctga caataacatt
     2461 tttacgatct tttctgatgt tttcttctgg actttattac tcatataaaa gtttaaattg
     2521 gcactcaaaa tagttaattt ttttgctgta ttagtcataa cagagttcct cctattgata
     2581 gatatttttt attttaggtt aaattttagt tcaattattg atatttattt ggtgattctc
     2641 tacttgtcgc gatagatttc atttttatgt taattatcaa atctgtccca tgtttcacag
     2701 tcatctttga tgtcatcttc attacaaagt agaacatcat aaaaataatc gaaagcttct
     2761 tgttcttcta ctaccatggc aaacacctta tatataggct tgtaaacctt t
//
LOCUS       DAVKZI010000102         2612 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKZI010000102 DAVKZI010000000
VERSION     DAVKZI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.103"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..456)
                     /locus_tag="VXB18_002187"
     CDS             complement(<1..456)
                     /locus_tag="VXB18_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383306.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLVNSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEK"
     gene            complement(514..1227)
                     /locus_tag="VXB18_002188"
     CDS             complement(514..1227)
                     /locus_tag="VXB18_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0383307.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1717..1824)
                     /locus_tag="VXB18_002189"
                     /pseudo
     CDS             complement(1717..1824)
                     /locus_tag="VXB18_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2246..>2612)
                     /locus_tag="VXB18_002190"
     CDS             complement(2246..>2612)
                     /locus_tag="VXB18_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0383308.1"
                     /translation="RNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEP
                     EEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQD
                     NNTIMAEAEKLLALLKESK"
BASE COUNT          811 a          493 c          406 g          902 t
ORIGIN      
        1 tttttctaaa aagtcgtcaa aattagaaaa aaatcgaaaa tacaatgcat tctcttggtg
       61 taaaatcgct ctttttaaag gataatactc tttaatatta ttaacttttt gttcgtaggc
      121 atattttgct acatgatcta ggtatatatc aaaaaagtca tgaggaaaat ctcccataca
      181 gccattacga ttcatattga ggctatattt tcgattagta agataattcg gaaatatatt
      241 tcctattact ctaagattat ctacttgtga atcccttctc ccaatataat ccccttcttt
      301 gactaatgat ggagatttcc aagtaaaaat taaatcgcca gagaaatttt tcttatcaaa
      361 aaacttaaaa agagattgat aaatactatt tactaattga caagtgtcag atgtaaattc
      421 ataattaaca gcttcattaa aatcaacttc agacatttca atgtactctt caatagtaat
      481 attagctttt ttgtagtcat tagctcgtct cctttaaaat gtgatctttt caagaatatt
      541 tttatctaaa caatccagca agtcttggta agaatagact tcgtaagtcg gctgggcttg
      601 tgtgtgattt tcgaggtgat gaggattata ccagatagtg tcaatccccg cattattgcc
      661 accttgaatg tcggcggtta gagaatctcc aatcatcagc gtcttttctt tactaaatcc
      721 agcaatttgc tggccaatct tttcataaaa aagagcatcc ggcttttgag tttgcaactg
      781 ttctgagata aagacttgat tgaaataagg tgctagacca gattgagcca aacgtcctgt
      841 ctgaatggca gtaatgccat ttgtcgcagc atacaagtta taatcacgct caatgaggct
      901 gtccaagaga tcatgagcgc ccgatagtgt ttgtccctgc tgggcgaggt aaaattggta
      961 acgctgggca agaaaactac cgtctttttc ctgtccaaaa tgagcaaata aacgagaaaa
     1021 gcgcgtgtta accagctctt gtttactgat tttcttcagc tccaagtctt tccagagagc
     1081 cttgttcata ggaacgtaat aatctttata agcctgaata tccgcaactc cttcttcttt
     1141 tagaagttgg gtcaaagcca catcctcagc agcatcaaaa tcaagaagag tgtggtcgag
     1201 gtcgaagagt agaaatttgt agaacaattt gaggttttcc tttctgaaaa ttcattaaga
     1261 acattatatc ataaagcacc tcatacaatt aactaattta atcacttaaa aaaaattcga
     1321 acactttcta tacaactgac agctcaaatc tttcagaata gaacaatact aactatcgaa
     1381 caccccgtct tcataaatac atatgtaatt ctaggcctag aattcctata aactaaatgc
     1441 tttcatactc ttccaagtaa ttgattgcct taaattttaa tttttgaagg tttctaaagc
     1501 tagaatagcc ccatcacaat cagttttgat tgattcacaa tttagaaaca ctatagtttc
     1561 actcctgtta aaataaaaag gaactgcata aagcaatccc tttctgattt tgaaatcatt
     1621 tacttaacat tttatagttg agataatcaa tagcttatct ataaaaagag ttatagtaaa
     1681 attccttatt tattgatttc aagctccgct aactgtataa gtaatcggaa catctttagc
     1741 tactttacta atcagttcaa caacaccttc tgcaatgtgt ttggaatgtg aaacgataac
     1801 aagaccaata ccaatacttt ccatcaaacc accccagttt ctaaaatagc agtaaagagt
     1861 aatcctgatg agaatgatcc aggatcaata tgtccaagaa accacatgct cctaagacaa
     1921 gagctaacag actggccatc aataatagta ttgttctttt tttcatcatt actccttaac
     1981 tagtgtttaa ctgattaatt agccagtaaa tagtttatct ttatttacac tatctgttaa
     2041 gatatagtaa aatgaaataa gaacaggaca gtcaaatcga tttctaacaa tgttttagaa
     2101 gtagaggtat actattctag tttcaatcta ctatattttg cacattttca tgaaaaaaat
     2161 gagaactaga actcacattc tgctctcatt tttcgttttc ccgttctcct atcctgtttt
     2221 taggagttag aaaatgctgc tacctttact tactctcctt taataaagcc aatagttttt
     2281 cagcttctgc cataatagta ttgttgtcct gggtgccaaa tagtaaatta ttttttaatc
     2341 ctgtgagagt ctctttggca ttggacttga taattggatc ctggattttt ccaagtaaat
     2401 cttcagcctc tctcagtttt tcttcaacct tttcagtctc gacctgaggt tcttctgatt
     2461 cctctggtga ttcttcttct ggttcctctg ttggttttgg agactctggt ttctcgcttt
     2521 gcggtttctc ttctcgagga gtttcttcct caggtttttc tgtctgaggt ttctccgttt
     2581 gattggtatc agcttgacca tttttgtttc tt
//
LOCUS       DAVKZI010000103         2592 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKZI010000103 DAVKZI010000000
VERSION     DAVKZI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.104"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..794
                     /locus_tag="VXB18_002191"
     CDS             <1..794
                     /locus_tag="VXB18_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0383309.1"
                     /translation="KIIYQFGYTNHRIKLILSNEDLGATNARNIDIKNSRGKYISFLD
                     DDDEYMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMV
                     HNIAGTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVLEFLVNYYAHS
                     KENGITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCK
                     ALKVIKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            804..2420
                     /locus_tag="VXB18_002192"
     CDS             804..2420
                     /locus_tag="VXB18_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383310.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          941 a          283 c          476 g          892 t
ORIGIN      
        1 ataaaattat ctatcaattt ggctatacca atcatagaat taagttaatt ttaagtaatg
       61 aagatttagg tgcaactaat gccagaaaca tagatatcaa aaattctaga ggtaagtata
      121 tatcattttt agacgatgat gatgaatata tgccagatcg aattttaaag ttgatggctt
      181 gttttaaaaa gagtagaatg aagaatttag ctttagttta tagttatgga ataataattt
      241 atccaaatgg tacacgagaa gaggagaaga ccgattttgt tggaaatccc ttgtttgttc
      301 aaatggttca caatatagca ggtacgtcat tttggttgtg taaaaaagag gtgctagaat
      361 taattaatgg ttttgagaaa atagattcac atcaggacgg tgttgtttta ttaaaactac
      421 ttgctcaagg ataccaaatt gatatagtgc tagaattctt ggtgaattac tacgctcaca
      481 gtaaagaaaa cggtatcact ggagtgacac aaaaaacaat taatgcagat gaagaatatt
      541 ataattactg taggaaatat tttaatttat tgagtttcaa cgagagaata ttggttacaa
      601 agaaatatta ttctttaaac ataaagcggt tactattaat aggagacaaa tgcaaggctt
      661 taaaagtaat caagaaggca agagaagaaa aaatttttaa cgaatttctt tttttgaaat
      721 atatgttatt atatcatttt ggttttttct attgtatata tgacaactat gttcaattaa
      781 aatttagaaa gtgagaaact attgtgtata ctattataaa atcaaatata aaaaaattta
      841 gtttattaac gatatttatt gttgctggtc aattattgct aatttatgca gcaactatta
      901 atgctctggt gttgaatgaa ttaattgcga tgaatttaga gcggtttttg aaattgtcaa
      961 tctaccaaat gattgtctgg tgtgggataa tattccttga ctgggtagtg aaaaattatc
     1021 aggttgaagt gatccaagag tttaatctag agattcgaaa tagagttgcc acagacatct
     1081 ctaactctac ctatcaagaa tttcatagta aatcatcagg aacatatctt tcgtggctaa
     1141 ataatgatgt tcagacttta aatgatcagg cttttaaaca acttttttta gtaataaaag
     1201 gaatttctgg tactatattt gcagttgtga ctcttaatca ctatcattgg tcattgactg
     1261 tagccacctt gttttcatta atgattatgc tacttgtacc aaaaatcttt gcatcgaaaa
     1321 tgcgagaagt tagtctaaat ttaactaacc aaaatgaagc ttttttaaaa tctagtgaga
     1381 ctatattgaa tggatttgat gtgttagcgt ccttgaatct tttatatgta ttgcctaaga
     1441 aaattaaaga agcaggaatt ttattaaaga tggttataca aagaaagaca actgtagaaa
     1501 cgttagcagg cgctattagc ttctttctca atattttttt tcagatatct ctcgtttttt
     1561 taacaggcta tcttgcaata aaaggaatag tgaaaattgg tactattgaa gcaataggag
     1621 cactaacagg tgttattttt acagcgctag gtgaattagg aggtcaatta tcctctatta
     1681 ttggtacgaa gcctattttt ttaaaattgt attcaattaa tccaattgag tcaaataaaa
     1741 tgaatgatat cgaaccaaat gaggtgaata gagattttcc gttatatgaa gcaaaaaata
     1801 tttgctataa gtatggagat aaagaaatat taaaaaactt aaatttttgt tttcaacgta
     1861 atgaaaagta tttaatttta ggtgaaagtg gaagcgggaa atctacatta ttaaaattat
     1921 tgaatggctt tttgagagat tatagtggag aattgcgatt ctgcggggat gatataaaaa
     1981 aaacctccta tttaaatatg gtttcgaatg ttctatatgt agatcaaaaa gcttatttgt
     2041 ttgaaggtac gattagagat aatattttat tggaagaaaa ttatactgat gaagaaatac
     2101 tacagtcttt agagcaagtt ggtttgagtg taaaagattt tcctaataac attttagatt
     2161 attatgttgg tgatgatggg agattactgt caggagggca gaaacaaaaa attactttag
     2221 ctagagggct aattagaaat aagaaaatag tattaattga cgagggaact tctgctatcg
     2281 ataggagaac ttcgttagcg attgaacgta agatattaga tagagaggat ttgactgtca
     2341 ttattgttac ccatgctccg catccggaac ttaaacaata ttttactaag atatatcaat
     2401 ttccaaagga ttttatttaa gaatataggg gagggaaaca tgagattcta ttgtgaagct
     2461 tatgaggtaa ttactgaaga gaaaaaagta tactttaatg atattgagtt agaagttaag
     2521 tattcctctg tcgaagaatt gtttataata tgtgagaaat tattagataa gaaaaaagta
     2581 tcattttttt at
//
LOCUS       DAVKZI010000104         2435 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKZI010000104 DAVKZI010000000
VERSION     DAVKZI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.105"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            30..548
                     /locus_tag="VXB18_002193"
     CDS             30..548
                     /locus_tag="VXB18_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0383311.1"
                     /translation="MNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKKDAHGIALK
                     LLSDPNREQFQHDNRQVELKILTRHIHRLKKKQSDWKVQYTRCLDIIFPELDKIVGKH
                     SEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQIEIRNSLD
                     KTIDFSYSLSFS"
     gene            complement(514..1989)
                     /locus_tag="VXB18_002194"
     CDS             complement(514..1989)
                     /locus_tag="VXB18_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0383312.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSARKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT          735 a          545 c          440 g          715 t
ORIGIN      
        1 aagatactgg acattatgcc tttaatctac tgaacttcct gcatgaacaa ggatataaag
       61 tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca cttcgcaaga
      121 ctaaaacgaa taagaaagac gctcatggca tcgctcttaa acttctttct gaccccaatc
      181 gtgaacaatt tcaacacgat aatcggcaag tagaactaaa aatactgact agacatattc
      241 atcgtctcaa gaaaaaacag tctgattgga aagtacaata cactcgttgt cttgatatca
      301 tctttcctga gttggataaa atcgttggaa agcattcaga atatacctac caactcttga
      361 cacgctaccc taatcctcag aaaaggattg aggcaggatt tgataagctg atagaaatta
      421 agcgattgac cgcttctaat tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc
      481 atcaaattga aataagaaat agtttagata aaactattga cttttcttat agtttgtctt
      541 tctcttaata acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc
      601 acgttccttg gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc
      661 caagatagga atccctggag gatagcacat gacaaattct ccacaaacct gtccaacaga
      721 atcatccaaa gttaaacttt ttcttgctga atagaaggct tcttgcggag acagcactaa
      781 ctcgggctga atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt
      841 aatatcagcc agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatagaaat
      901 ataggccaag atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa
      961 gaggtcataa acctcgatac ctgttaagcc aataccctga gtgtaaactg acagcttagt
     1021 tacgtcaaaa tcgcaaaccg aaacaccgtc tattaattct tttgagtagg catagtagcc
     1081 accgatagca ttgatttcac ggcgggcata ctcagatagc tcaatgactt tctcaaacga
     1141 ctctttacca cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaacaagta
     1201 agaggcagat gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg
     1261 ctccccgatt aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac
     1321 tgctgccata tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa
     1381 atgcgctcca tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt
     1441 caaccccttt aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt
     1501 agcatctgga tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat
     1561 accaatctta ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa
     1621 cgcattgata gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca
     1681 ggttgccaga atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg
     1741 gctagctcca aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg
     1801 gcctaaatta tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa
     1861 gagttcgaca agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac
     1921 aatccttttc ttgcgtaact tcaccaaggc ttcataaatt ggggcttggt tttgatctaa
     1981 ctctttcaaa acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa
     2041 ggttgactca tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat
     2101 tttggtttct gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt
     2161 acgtacttta ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg
     2221 aattaggaca agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat
     2281 gtggcttttc aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg
     2341 ggtttatatt tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt
     2401 ttaagaactt gtaaagtatt ttttgataaa aaaca
//
LOCUS       DAVKZI010000105         1821 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKZI010000105 DAVKZI010000000
VERSION     DAVKZI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.106"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>1821
                     /locus_tag="VXB18_002195"
     CDS             <1..>1821
                     /locus_tag="VXB18_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0383313.1"
                     /translation="SANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSN
                     RLTSSEQGTTTQISNLSNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSA
                     NKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQ
                     LFQVEVGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNAT
                     KNENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSS
                     KKLSTSRCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPH
                     PEDAVADANKKLEATQTKMTQLAGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHI
                     TGETLIDRAVIKSAMVDKLKTGNFEAGSVTTTILDAEAVTAEKLKVDDALIKKLTATD
                     AFIDQLISKRIFSIKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVG
                     MGNGAGHGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWW"
BASE COUNT          579 a          327 c          423 g          492 t
ORIGIN      
        1 agtgcgaata aagacatcgc tagtcaaatc gctagctatc gtcaatctgt agatggtaag
       61 ttcacggata tttcaagtca gataactact tataagcaag atgtgggcgg tcaaatcagt
      121 ggtctatcaa atagacttac aagcagtgag caaggaacca ctactcagat ttcaaatctt
      181 tcaaatcgga taaacagtaa taaacaaggc acagataatc agatttcaaa tttaaagact
      241 caggtcgcta caaacaagga taatgctgaa cgacaaatgg gtagaatatc tgatcaggtt
      301 tctgcaaaca aagcgaatgc tgatagtcaa tttgcgaatg tgaccaatca actagcgcga
      361 aaagtagaga ctactgactt ccagcgtgtt aaggaaacca gtaaacttta cgagcggatt
      421 ttgggcaata ctgaaaatgg aattgcggat aaggttgctc gcatggctct gactaatcaa
      481 ctgtttcagg ttgaggttgg gaaatatagt gtaagcggcc ctaacctcat taagaatagt
      541 gattttaaaa atgctacgaa tgaatggggc tcaactcaaa atttaggaag attggttaag
      601 catagctttt atcacaacgg gcagaaagac cttatgcgtt taagtaatgc aactaaaaac
      661 gaaaactttt tgtatagtca ccgttttaat cttgaacgaa atactgacta tgtactgaat
      721 tttagaggat ttaacaacag tgctctcgca agctatgatg tttatatttt gggacgaaga
      781 gcaggcgaga gcgatggatt cacaatcgtt aagaaagttg ttagcagcaa gaaactatct
      841 acctctagat gcgaagatgt ctcagtaact tttaattccg gagaaatgga taatgcttac
      901 attcgttttg ataacaatgg ctcatcatca ggaacagctg atttgtatat tacagaagtt
      961 gacttgtaca aaggttataa acctagaaca tggcaaccac atccagaaga tgcagtcgca
     1021 gatgcgaata agaagcttga agcaacgcaa acaaaaatga ctcaactagc tggctcatgg
     1081 gcagttcaaa acatcaactc ggctggagat atcatctctg gaatcaatct tggcgccaat
     1141 ggacataacc gctttgttgg gaaattgacc cacatcactg gagagaccct gattgacaga
     1201 gcagtcatca agtctgccat ggttgataag ctcaaaacgg gcaattttga agctggttcg
     1261 gtcacgacta cgatattaga cgctgaagcg gtaactgctg agaagttgaa agttgacgat
     1321 gcgcttatta aaaaattaac tgcaactgat gcttttattg accaactgat atctaaacgt
     1381 atcttctcta ttaaggttga gtccgtcatt tctagctcaa ccttcctaga agcctatcaa
     1441 ggccgaatcg gtggattcac acttggtcaa tttgaccagg gtggcggtcg ctggatttca
     1501 ggtgtcaatc agttctctgt tggtatgggg aatggtgccg ggcatggagt ccggacagcc
     1561 ttctgggcga actggggaaa taattggaac tatgccggac ctaaagcatg gaacgtcaat
     1621 actgatggga aaatgtactg taggaatgaa gtcggttttt atgatcaagt ggatttttcg
     1681 aattcatcga gagcaaactt ctatgggaat actacttttt ctcgttctcc tgtgttttca
     1741 aatggtatcg aacttggaag taaagatgtg cttggtgatg gttggaatcc caaaggcgga
     1801 aggaatgcgg ttgtttggtg g
//
LOCUS       DAVKZI010000106         1571 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKZI010000106 DAVKZI010000000
VERSION     DAVKZI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1571
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.107"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..1551
                     /locus_tag="VXB18_002196"
     CDS             <1..1551
                     /locus_tag="VXB18_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0383314.1"
                     /translation="LVRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQ
                     LLSLYPTLKNFAKYDCIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLF
                     YIHLDYRILALNTAENLESRNSSIVPVKDGKQILIDQLFDGECDDIYLLTVHSPMNKA
                     LEILSEKYKQISGKNIKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQ
                     EITSFRQTKSINQNISKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRY
                     FEKTKRKLTVPKSYQEFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRE
                     RLAQSRMNLAVLPQVLTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSP
                     LFDGLNVSAQFEFATATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILL
                     TSLGGFLPSKYVMQNRMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELI
                     ESVKHRYG"
BASE COUNT          553 a          196 c          267 g          555 t
ORIGIN      
        1 ttggttcgga ctgaaaagct atctaattta tattttattt cacttactaa tgaaaaagaa
       61 cattctttat ttgaatattt aactcaaaaa ataaaaaact caactcatat acaagtgcaa
      121 gaacgtttac aattgttgtc tctataccct actctaaaaa actttgcaaa gtatgattgt
      181 atatttgttg atgatgaaga tttgatgcac acgctattag acttatttga ttggtttact
      241 ataattgata gaccaaaaat atgtttgata ggttcacgtg tttggttcga aaaaagaaat
      301 cttttttata tacatttaga ttatagaata ttggcactca atactgccga aaatttagaa
      361 agtagaaata gttcaattgt accagttaaa gatggcaaac aaattttaat tgatcaatta
      421 tttgatggag aatgtgatga tatttattta cttactgtcc attcaccaat gaataaagcc
      481 ttagaaattt tatcagaaaa gtataaacaa atttctggga aaaatattaa aattatcgag
      541 aaaagatatg atgaactttt ggagatgatt gagtctggcg atgtttcatc cagttttgat
      601 atgattagaa tggatatggc ttggcttcca acatttggga aaaagtattt tcaagagatt
      661 acaagcttta gacaaacaaa aagtattaat caaaatattt ctaagtcggt gtctcgagag
      721 tatatgtata ttgatcagaa gcaatatact tttccattgg atgttagtag tcagatttta
      781 gtatatagaa aagacttatt tgaagattca tttttacaaa gacgatactt tgaaaaaaca
      841 aaaagaaaat taactgtacc aaaaagttat caagagtttg atgagttaag tgaatttttt
      901 acattaacag aaaatccatt ttcacctaca ctttatggcc atagtttagc tttaagttct
      961 tcagtgagag cagcatgtga atttattcct cggtttcgtg agagattagc acaatctaga
     1021 atgaatcttg ctgtacttcc tcaggtttta actgagtatg agaaaagtta tcagtttacc
     1081 gaaaaatcat ttaattcttc gtggaacgat ttcgttacga acttaaacag tggtaaaact
     1141 tcaatggaaa taattttttc aaattatact agtccattat ttgatggtct caatgtttct
     1201 gctcagtttg agtttgcaac tgccactata cctggtaata ctcctgtgat aggtggtggc
     1261 tcaattggaa tttctaaata ttcaaataga gtggaagaat gtctaaactt tattaattgg
     1321 ttatattctg aagagatttc tattttacta acatctctgg gtggtttttt accatcaaag
     1381 tatgtcatgc aaaataggat gttacaattt caatatccat ggttatctag tttagaagat
     1441 acatttagta ttgggagtag aacaaaatgg tacggcttta atactgattt tagatttgag
     1501 cagatgttag ggcaagagtt aatagaaagt gtgaagcata gatatggata aattaatact
     1561 aaatttttat t
//
LOCUS       DAVKZI010000107         1486 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKZI010000107 DAVKZI010000000
VERSION     DAVKZI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.108"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>1486
                     /gene="pcpA"
                     /locus_tag="VXB18_002197"
     CDS             <1..>1486
                     /gene="pcpA"
                     /locus_tag="VXB18_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0383315.1"
                     /translation="AAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLT
                     VEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQAFSYYPDET
                     GRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFDFSELEEIEL
                     PASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSN
                     LFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELAS
                     YSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAFYGNLELKEL
                     ILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTEFSV
                     KKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQG
                     VVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWV"
BASE COUNT          561 a          206 c          257 g          462 t
ORIGIN      
        1 cagctgcggt tattttagca gcatatgtcc ctaatgaacc aatcctagca gatactccta
       61 gttcggaagt aatcaaagag actaaagttg gaagtattat tcaacaaaat aatatcaaat
      121 ataaggttct aactgtagaa ggtaacatag gaactgttca agtgggtaat ggagttactc
      181 ctgtagagtt tgaagctggt caagatggaa aaccattcac gattcctaca aaaatcacag
      241 taggtgataa agtatttacc gttactgaag tagctagtca agcttttagt tattatccag
      301 atgaaacagg tagaattgtc tactatccta gctctattac tatcccatca agcataaaaa
      361 aaatacaaaa aaaaggcttc catggaagta aagctaaaac tattattttt gacaaaggca
      421 gtcagctgga gaaaattgaa gatagagctt ttgatttttc tgaattagaa gagattgaat
      481 tgcctgcatc tctagaatat attggaacaa gtgcattttc ttttagtcaa aaattgaaaa
      541 agctaacctt ttcctcaagt tcaaaattag aattaatatc acatgaggct tttgctaatt
      601 tatcaaattt agagaaacta acattaccaa aatcggttaa aacattagga agtaatctat
      661 ttagactcac tactagctta aaacatgttg atgttgaaga aggaaatgaa tcgtttgcct
      721 cagttgatgg tgttttgttt tcaaaagata aaactcaatt aatttattat ccaagtcaaa
      781 aaaatgacga aagttataaa acgcctaagg agacaaaaga acttgcatca tattcgttta
      841 ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg tttagaaaaa atcggtactt
      901 ttgcatttgc ggatgcgatt aaacttgaag aaattagctt accaaatagt ttagaaacta
      961 ttgaacgttt agccttttac ggtaatttag aattaaaaga acttatatta ccagataatg
     1021 ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa attaaaaagt ttaacaattg
     1081 gtaataatat caactcattg ccgtccttct tcctaagtgg cgtcttagat tcattaaagg
     1141 aaattcatat taagaataaa agtacagagt tttctgtgaa aaaagataca tttgcaattc
     1201 ctgaaactgt taagttctat gtaacatcag aacatataaa agatgttctt aaatcaaatt
     1261 tatctactag taatgatatc attgttgaaa aagtagataa tataaaacaa gaaactgatg
     1321 tagctaaacc taaaaagaat tctaatcagg gagtagttgg ttgggttaaa gacaaaggtt
     1381 tatggtatta cttaaacgaa tcaggttcta tggctactgg ttgggttaaa gacaaaggtt
     1441 tatggtatta cttaaacgaa tcaggttcca tggctactgg ttgggt
//
LOCUS       DAVKZI010000108         1385 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKZI010000108 DAVKZI010000000
VERSION     DAVKZI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.109"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(205..621)
                     /locus_tag="VXB18_002198"
     CDS             complement(205..621)
                     /locus_tag="VXB18_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0383316.1"
                     /translation="MITIKKQEFVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLAI
                     YVALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSTLMKEALEDYKDAYQVQ
                     LVTEQTERTLGFYCSMGFEILSTYDCIGMTWINREK"
     gene            complement(633..1328)
                     /locus_tag="VXB18_002199"
     CDS             complement(633..1328)
                     /locus_tag="VXB18_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0383317.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELTFIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMEELVSLLNQMLARKDRFYYAIIDRSTGKVLG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAF
                     NLPSRRAAERLGFIYEGTFRQAVVYKGRTRDTDWLSMTDKDWPKVKDRLETWLRPENF
                     DKNGQQYKSLREL"
BASE COUNT          409 a          334 c          228 g          414 t
ORIGIN      
        1 ttttctcaaa ttataccatt tttaaaaaaa tttctatcag catcacctca ccctacaaaa
       61 aagccacctg attaggtgac ttcattagga gattatgatg aaaaaagttt taggatttca
      121 ttaaataaag ttaggaggtc tttatttaat gactatatga tactagacca gccttaaact
      181 ttgcttaaga acaaccaagt tttattattt ttctctgttt atccaagtca ttcctataca
      241 atcataggtg gataagattt caaagcccat agaacaatag aagcccaagg ttctttctgt
      301 ctgttctgtt accagctgga cttgataggc atctttgtaa tcctctaaag cctctttcat
      361 tagggtacta ccaatccctt gacgttgata gattggtaaa acgattaaat cctgaaccaa
      421 tactgatgag aatccatctc caaccaaacg aatcaagccc accacagcat cgccatcaag
      481 cgccacataa atcgctaatg aatgagataa ggcctgctcc agcatctctg gttgatgggt
      541 ataatttgtc caaccgacag cctgatagag atgcaaaaca tcctctagct tgacaaattc
      601 ttgcttttta atagtaatca tctcaacacc tcttaaagct ctctcaagct cttgtactgc
      661 tgtccatttt tatcaaaatt ttcaggacgc aaccatgttt ccaaacgatc tttgactttg
      721 ggccagtcct tatcagtcat agacaaccaa tccgtatccc tcgtacgccc cttataaacc
      781 actgcctgac ggaaggttcc ttcataaata aagcccaaac gttctgcagc tcgtcttgat
      841 ggcagattaa aagcatcgca tttccactca tagcgacgat agttaagctc ttcaaagaca
      901 tagcgagcca gtagatactg ggcttctgtc cctatccgtg tccccctgag ttctggagaa
      961 aaagtgacag ctcccacttc tattactcgg ttattctggt caatgcgcat gagagaaaaa
     1021 gttcccaaaa ccttaccagt tgacctgtct atgattgcat agtaaaaacg gtccttacga
     1081 gccaacatct gatttaaaag gctgaccagt tcctccatgt ctgctactgg ttcctgaaag
     1141 aggtaggtcc acatctcctg aggagtatcc gggccataaa cagctaacaa atcctccgca
     1201 tgtttttcta ccgagagagc ctctatccga gcataacgtc cttctaagaa atcaataaaa
     1261 gtcagttcac ctggtgtata accttccatt gactcaccaa tcatctgacc atattcgttt
     1321 actggtataa ctttctcctt gtttcgcttt tcaaacttta tagttgccca tagtatagcg
     1381 tattg
//
LOCUS       DAVKZI010000109         1336 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKZI010000109 DAVKZI010000000
VERSION     DAVKZI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.110"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            27..>1336
                     /locus_tag="VXB18_002200"
     CDS             27..>1336
                     /locus_tag="VXB18_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEV0383318.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTE"
BASE COUNT          507 a          158 c          240 g          431 t
ORIGIN      
        1 acaagctaat gtaggatagt taaaatatgg aagaaaatta taatttatct ataactcaaa
       61 taaagaattc tattaaagaa aattccttag ttttgtttgt tggtgcagga atatcagcta
      121 attctaatct accaacttgg ggagaattga ttcaatcatt aaaaaaagaa ttgaacatac
      181 cagaagaaag aacagatagt ccactgagaa ttgctcagta ttattatgat acttttggga
      241 aaaatcagta cacaaagaag atagaagaaa ttttctttaa gaagggattg agtaaaccaa
      301 atgagttaca taaattaata gaaaaaattg caccaaaaca tattattacg acaaactatg
      361 attcacttct ggagagtcaa tttgaaagtg gcttgttaaa gtacaatgta gtcgctgagg
      421 ataaagacat cccttatacg agttcggaaa gatacttgat taaaatgcat ggtgacttca
      481 gtaagaaaaa tattgttttg aaagaagatg attatttaga ctatcatttg aacttcccaa
      541 tgatttctac tttaatccag tcattgataa tgaatcatac tctattgttt gtggggtatt
      601 ctctaagtga ttcgactttt aattcaattt ttagaatgat tcaaaataca tttaaattgg
      661 atgctaaaaa tgcttatttt tatactcccg aggaaccgtc tatgatcatt cgagagtatt
      721 ataagaagca aggaattttc attatctcta atgaagagaa tctaggtcag gagacatcag
      781 aaaaacagaa caaattgtat tgcaggacaa aagatttttt agaggttcta tcagaaaacc
      841 gaagtcaaga tgtaaataat gctgatgatt tatggaatca actggctttt ttagatagac
      901 ttagttttat tgatgcgaaa gatttttcta gatattctga tttaaagaaa agggctttaa
      961 actgggatga tgagtattgc tggtttggaa atgatcaatt aagatttgaa attgatggtc
     1021 atgaagaatt acgaattatg gtatctaaaa aatctttatt aaatcgcttt ctagatatgg
     1081 agattggtga gcctagggat ttaaagggga atcgattctt aagtaaggct tttaagttgt
     1141 atgaagaaaa acaatattct ttagcaaaag caaaatttag agaactagct aatatagcat
     1201 ttcgtcagaa agactatttt aatttcttag tttgtgaatt taattttcag caaattcaaa
     1261 taattgatag atacgaaaaa acacctagtt atgcagagcc actttatgat ggagaattaa
     1321 gcgaattaac agaaca
//
LOCUS       DAVKZI010000110         1304 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKZI010000110 DAVKZI010000000
VERSION     DAVKZI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.111"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            37..821
                     /locus_tag="VXB18_002201"
                     /pseudo
     CDS             37..821
                     /locus_tag="VXB18_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(856..1065)
                     /locus_tag="VXB18_002202"
                     /pseudo
     CDS             complement(856..1065)
                     /locus_tag="VXB18_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1231..1304)
                     /locus_tag="VXB18_002203"
     tRNA            complement(1231..1304)
                     /locus_tag="VXB18_002203"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1268..1270),aa:Asn,seq:gtt)
BASE COUNT          432 a          265 c          214 g          393 t
ORIGIN      
        1 attatggttc tgattttcta gtataaaaaa attcaaacta gaattcttct tagaaaaggc
       61 cgttttaagt gctatcattg ctcaaaaatg gaggtcgctg agacttctat cgtcaagaag
      121 aatcatcaaa ttccttgtat catcaaccaa aagattgatc agaagctaat tgaaaagact
      181 tctatgaccg acattgatca tcagttgtct atttcaactt caactgtcat tcgcaagatc
      241 aatgattttc actttgagca tgatttttcg cgtcttcctg agattatgtc ctaggacgtt
      301 gaaacagtct ggggagtgac tgtttcaatc gggagataga gatgagcttt attgctcagg
      361 actttgataa gctcaatatc ataactgttc ttgagagcag aacacaagcc atcatccgaa
      421 atcccatgaa tacaaggcta tcaagcgata ctgaaagctc attcaacaag atagtcagaa
      481 actgagtgat aaacgatttt atcgccctac ttttcgtatg cacttgacta ataaagaaat
      541 tctagataaa cttttgagct attccgaaga cttgaaacac cactataatc tctatcagct
      601 cttgcttttc caccctgttt aaaaccttcc tcaaagataa agagaaaatc gtcaacgccc
      661 ttcaattacc ttattccaac gccaaactgg aagccaccaa taatctcatc aaacttatca
      721 agcacaatgc ctttggtttt aggaactttg aaaacttcaa aaaagaaagg acgaaatttg
      781 tcctttctag atcttcgctt tcttcaaccc actacagttg acaaagaacc gaaaaatgtc
      841 tcgcctctaa tatagtcaat tgaaacaaga gcaggacaaa agagcctcgt aaaaggtatg
      901 gcaacgtggt aatacctttt tgaggttctt tttgatatga gcccatgttt tctcaatagg
      961 attgtactca ggtgagtagg gaagaagagg taaaagttta tgcccaaact cttcacataa
     1021 aagttctagc ttacccattc tatggaatct tgcattgtcc ataatatagt agattgaaac
     1081 tagaatagta cacctctact tctaaaacat tgttagaatt cgattttact gtcctgatcg
     1141 atttgtccta ttcttatttc attttgctat aacacgaaat agattattat tacataacaa
     1201 aaaagaggtc taaacctctt aactaaatta ctccgccagt aggactcgaa cctacgacat
     1261 catgattaac agtcatgcgc tactaccaac tgagctatgg cgga
//
LOCUS       DAVKZI010000111         1294 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKZI010000111 DAVKZI010000000
VERSION     DAVKZI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.112"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            110..>1294
                     /locus_tag="VXB18_002204"
     CDS             join(110..449,449..>1294)
                     /locus_tag="VXB18_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0383319.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYAYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKEIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRI"
BASE COUNT          464 a          219 c          285 g          326 t
ORIGIN      
        1 gaaattgagt tatgaagata aagttcagat ctatgaacta agaaagcaag gacaaagctt
       61 caaacagctt tcaaaaagat ttggtgtgga tgtttctggt ctaaagtaca tggtgaaatt
      121 aattgaccgt tatggcatag aaatcgttaa aaaagggaag aatcgtcact attcttctaa
      181 attgaaacaa gaaatgatgg ataaagcctt actggaaggt tgttcacaaa gaagtattag
      241 tcttgattat gccctcccaa accaaggaat gctttcattt tggccggcac aatacaagaa
      301 aaacgggtat actattgttg agaaaacaag agggagacca gctaaaatgg gacgtaaacg
      361 gaagaagact tgggaagaaa tgacagaact agaacgactc caggaggaga atgaacgctt
      421 acggactgag gtggcctacc taaaaaagtt aaaagagtta gaggaaaggg acgaagccct
      481 agagcgagaa aggcagagac agttagagaa atggtttcag gaggatttcg actagatttt
      541 cttcttgaaa cagcacgttt agctcgctcg acttactatt atcagttgaa acaactggat
      601 ggggttgata aagataaaga gattaaaacc gaaattcagg gcattgataa tgaacataaa
      661 ggcaactatg cctatcgtcg aatccattta gaactaagga atcgtggttt tgtggtcaat
      721 cataagaaag ttcaacggtt gatgagaatt cttggtttaa cggctcgaat tcgccgtaaa
      781 cggaagtatt cttcctacca aggagagatt ggcaagaaag cagagaatct cattcaacgc
      841 cagttcgaag catcgaggcc aatggaaaag tgctatacag atgtgacaga gtttgccatt
      901 ccaaatagca cacagaaact ctatttatca ccagttttag atggttttaa cagtgaaatc
      961 attgcttatc atctttctac ttcgccaaac ttagaacaag tgaagagtat gttagaacag
     1021 gcctttacag agaaatacta tgagaatacg attctccata gtgaccaagg ctggcaatac
     1081 caacacgatt cttatcatcg gttcctagag agtaaggaaa ttcaagcatc catgtcacgc
     1141 aagggcaaca gcccagacaa cggcatgatg gaatctttct ttggcatttt aaaatccgaa
     1201 atgttttatg gctatgagaa gaactttaga tctttagaaa accttgaaca agctattgtg
     1261 gactacattg attactacaa caacaaacga atta
//
LOCUS       DAVKZI010000112         1065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKZI010000112 DAVKZI010000000
VERSION     DAVKZI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.113"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>1065
                     /gene="phtD"
                     /locus_tag="VXB18_002205"
     CDS             <1..>1065
                     /gene="phtD"
                     /locus_tag="VXB18_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0383320.1"
                     /translation="LRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPID
                     EKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKT
                     DLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDI
                     LAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYV
                     TPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDLGNTEAKGAEAIYNRVK
                     AAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLL
                     ATVKYYVEHPNERPHSDNGF"
BASE COUNT          345 a          222 c          230 g          268 t
ORIGIN      
        1 cccttcgtta tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac
       61 aatcgactcc ggaacctagt ccaagtctgc aacctgcacc aaatcctcaa ccagctccaa
      121 gcaatccaat tgatgagaaa ttggtcaaag aagctgttcg aaaagtaggc gatggttatg
      181 tctttgagga gaatggagtt tctcgttata tcccagccaa ggatctttca gcagaaacag
      241 cagcaggcat tgatagcaaa ctggccaagc aggaaagttt atcgcataag ctaggagcta
      301 agaaaactga cctcccatct agtgatagag aattttacaa taagacttat gacttactag
      361 caagaattca ccaagattta cttgataata aaggtcgaca agttgatttt gaggctttgg
      421 ataacctgtt ggaacgactc aaggatgtct caagtgataa agtcaagtta gtggatgata
      481 ttcttgcctt cttagctccg attcgtcatc cagaacgttt aggaaaacca aatgcgcaaa
      541 ttacctacac tgatgatgag attcaagtag ccaagttggc aggcaagtac acaacagaag
      601 acggttatat ctttgatcct cgtgatataa ccagtgatga gggggatgcc tatgtaactc
      661 cacatatgac ccatagccac tggattaaaa aagatagttt gtctgaagct gagagagcgg
      721 cagcccaggc ttatgctaaa gagaaaggtt tgacccctcc ttcgacagac catcaggatt
      781 taggaaatac tgaggcaaaa ggagcagaag ctatctacaa ccgcgtgaaa gcagctaaga
      841 aggtgccact tgatcgtatg ccttacaatc ttcaatatac tgtagaagtc aaaaacggta
      901 gtttaatcat acctcattat gaccattacc ataacatcaa atttgagtgg tttgacgaag
      961 gcctttatga ggcacctaag gggtatagtc ttgaggatct tttggcgact gtcaagtact
     1021 atgtcgaaca tccaaacgaa cgtccgcatt cagataatgg ttttg
//
LOCUS       DAVKZI010000113         1054 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKZI010000113 DAVKZI010000000
VERSION     DAVKZI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.114"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..555
                     /locus_tag="VXB18_002206"
     CDS             <1..555
                     /locus_tag="VXB18_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0383321.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VXB18_002207"
     CDS             complement(503..1048)
                     /locus_tag="VXB18_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0383322.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVKZI010000114         1044 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKZI010000114 DAVKZI010000000
VERSION     DAVKZI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.115"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            83..433
                     /locus_tag="VXB18_002208"
     CDS             83..433
                     /locus_tag="VXB18_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0383323.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            648..764
                     /locus_tag="VXB18_002209"
                     /pseudo
     CDS             648..764
                     /locus_tag="VXB18_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            757..990
                     /locus_tag="VXB18_002210"
     CDS             757..990
                     /locus_tag="VXB18_002210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383324.1"
                     /translation="MFSQLHMREEQVLLAQDYPLETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT          323 a          207 c          232 g          282 t
ORIGIN      
        1 atatttctat aaattaattt gactttcctg atagagttat tcacatctta tttcaactca
       61 ctatagaagg aggaatagga ggattctcag acatccgggc atcagcccaa ctaatgattt
      121 gattgctaag aaaatattca gcaatccaga aatcacttgt caatttattc gcgatatgct
      181 ggacttgcca gcaaaaaatg tgaccatttt ggagggaagc gatattcacg tattactctc
      241 catgccttac tcggtgcagg atttttatac cagtatagac gtcttggcgg agttggataa
      301 cggtactcaa gtaattattg agattcaagt ccatcatcag aattttttca tcaatcactt
      361 gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa aaaattcgtc agcgagaagg
      421 tgatactcac tagagctaca aacacatcgc tcctgtttac gccattgcta tcgtggatag
      481 taattatttc tcagatgacc tggcttttca tagctttagt atgcgcgaag acacaacagg
      541 tgaggtattg gcgattacca acaatggaca ggaaaaccat ctggttaaga tggcattctt
      601 ggaattaaaa aatacagaga aaccagcaaa gacaaggttc gcaagccatg gttggagttt
      661 ttcggcaaca agccctttac ccagcaacct gagcgagcca tcagccaagc agaccaactg
      721 ctggactaca agagctggtc cgaggaggac aggaaaatgt ttagtcaact acatatgcga
      781 gaagaacaag tcttgttagc acaggactat cccttggaaa ctgctagggc tgaaggcctt
      841 gaacaaggac tagagcgtgg gaaagttgaa ggaagggaag aaaggaaact ttttgccttc
      901 ctagacatag tacgccaagg tcttctgact tctgaggttg ccagccagca attaggtatg
      961 tcagtatctg aatttgaggc actgttgtaa aatggctcca taatatccat agtgggtaaa
     1021 tcccctatgg atattatgga gcct
//
LOCUS       DAVKZI010000115         1019 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVKZI010000115 DAVKZI010000000
VERSION     DAVKZI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.116"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            22..234
                     /locus_tag="VXB18_002211"
     CDS             22..234
                     /locus_tag="VXB18_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0383325.1"
                     /translation="MSIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKIEDMYDIKV
                     ADEAYKKWVECGKKSISHEEMMRRYG"
     gene            227..958
                     /locus_tag="VXB18_002212"
     CDS             227..958
                     /locus_tag="VXB18_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0383326.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDKEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
BASE COUNT          389 a          141 c          159 g          330 t
ORIGIN      
        1 aataatgttg ttactacaca aatttctatt caacttagtc aagagttaaa ttctttatta
       61 aatgctattg ttgaagaaaa taatacaaca aagactgact ttattagaca agctgttata
      121 gagaaaattg aagatatgta tgatattaag gtcgctgatg aagcttataa aaaatgggtt
      181 gaatgtggca aaaaatctat ctcacatgaa gaaatgatga gacgctatgg ctaaattata
      241 cgcaatatct gatatacatg gatacttgga tgaattcaga gacgctctca ataaagtaaa
      301 tttaaacgat aaagataatc gcctattttt actaggagat tatcttgata atggacttca
      361 atcttttcaa gtcatttcca aaataatcga acttgaggag gtttatccta atcaaattat
      421 tactcttcta gggaatcatg aagaatggtt ttatgattgg ttgattttag ataaacctac
      481 tgcttcagca tttccagaaa caataaaaag cttcttctct ccagaggaat tgaactatat
      541 ttttaaatcg aatgctaaca actttgaaac aggtgttaga aatgaaatta aaaataatat
      601 caaattcaac ccatttataa actggtttaa aaagcgatat agggataaac gctattatga
      661 aactgatacc caaatttttg ttcatgcagg cattgataaa gaagcaggaa tgctttggaa
      721 agaactaacg agttcaaaga tatttacaaa caaatttcca attaccactg gtagatttca
      781 taaagctatt atttcgggcc atattgcttc ttgggaagta gctaaagata gaagatacct
      841 aggtaagatt tactatgata gtaaaagtca ttacttaatt gatggagatg taacgaatag
      901 caaaacaata cctgttcttt actatgatac aattacccaa aaatatcact ttctataact
      961 tttaatcatg tgcttttata tgaaattagt aattattagt aacaattcca agaaatttc
//
LOCUS       DAVKZI010000116         1002 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVKZI010000116 DAVKZI010000000
VERSION     DAVKZI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.117"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(57..140)
                     /locus_tag="VXB18_002213"
     tRNA            complement(57..140)
                     /locus_tag="VXB18_002213"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Leu,seq:caa)
     gene            complement(150..221)
                     /locus_tag="VXB18_002214"
     tRNA            complement(150..221)
                     /locus_tag="VXB18_002214"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(187..189),aa:Gln,seq:ttg)
     gene            complement(232..304)
                     /locus_tag="VXB18_002215"
     tRNA            complement(232..304)
                     /locus_tag="VXB18_002215"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(269..271),aa:His,seq:gtg)
     gene            complement(319..389)
                     /locus_tag="VXB18_002216"
     tRNA            complement(319..389)
                     /locus_tag="VXB18_002216"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(355..357),aa:Trp,seq:cca)
     gene            complement(394..474)
                     /locus_tag="VXB18_002217"
     tRNA            complement(394..474)
                     /locus_tag="VXB18_002217"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(438..440),aa:Tyr,seq:gta)
     gene            complement(487..559)
                     /locus_tag="VXB18_002218"
     tRNA            complement(487..559)
                     /locus_tag="VXB18_002218"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(524..526),aa:Phe,seq:gaa)
     gene            complement(563..636)
                     /locus_tag="VXB18_002219"
     tRNA            complement(563..636)
                     /locus_tag="VXB18_002219"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(600..602),aa:Met,seq:cat)
     gene            complement(647..736)
                     /locus_tag="VXB18_002220"
     tRNA            complement(647..736)
                     /locus_tag="VXB18_002220"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(698..700),aa:Ser,seq:tga)
     gene            complement(820..893)
                     /locus_tag="VXB18_002221"
     tRNA            complement(820..893)
                     /locus_tag="VXB18_002221"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(857..859),aa:Ile,seq:gat)
     gene            complement(928..998)
                     /locus_tag="VXB18_002222"
     tRNA            complement(928..998)
                     /locus_tag="VXB18_002222"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(964..966),aa:Gly,seq:tcc)
BASE COUNT          282 a          274 c          228 g          218 t
ORIGIN      
        1 aaatttctta tgacataaca aaaagacaag gtcctaaaac cttgtcttta atactatacc
       61 ggcggccggg gtcgaaccgg cacgtccttg cggacactgg attttgagtc cagcgcgtct
      121 gccaattccg ccacgccggc aaatagtaac tggggtagct ggattcgaac caacgcatga
      181 gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc aatataaaat aggcgagtga
      241 tggggatcga acccacgcat gccagagcca caatctggtg tgttaaccac ttcaccacac
      301 ccgccataat tctattaaca cgggcagtag gaattgaacc cacactgaag gttttggaga
      361 ccttagttct acctttaaac tatgcccgta aaatggaagg ggagggattc gaacccccga
      421 acccgaagga gcggatttac agtccgccgc gtttagcctc ttcgctaccc ttccaaaata
      481 tataaatggc gcgagacgga atcgaaccgc cgacacatgg agcttcaatc cattgctcta
      541 ccaactgagc taccgagcct tattgcggga gcaggatttg aacctacgac cttcgggtta
      601 tgagcccgac gagctaccga gctgctccat cccgcgttaa tataaaagga ggatgtggga
      661 ttcgaaccca cgcacgcttt tacacgcctg acggttttca agaccgttcc cttcagccgg
      721 acttgggtaa tcctccaaaa tagttttata cgggaacaag cccgtgtcct cttagtgaac
      781 agataatatt ccaatcccct agtaatggac taaacactat gggcacgagt ggactcgaac
      841 caccgacctc acgcttatca ggcgtgcgct ctaaccacct gagctacgcg cccaagtcaa
      901 aaacttggta caaagaacaa agttcaaagc gggtgacgag aatcgaactc gcgacaacag
      961 cttggaaggc tgtagtttta ccactaaact acacccgcta aa
//
LOCUS       DAVKZI010000117          956 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVKZI010000117 DAVKZI010000000
VERSION     DAVKZI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.118"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..842
                     /locus_tag="VXB18_002223"
                     /pseudo
     CDS             1..842
                     /locus_tag="VXB18_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            835..>956
                     /locus_tag="VXB18_002224"
     CDS             835..>956
                     /locus_tag="VXB18_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0383327.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEV"
BASE COUNT          354 a           83 c          201 g          318 t
ORIGIN      
        1 atgttaaaaa aacttgacaa gaatggattt ggaaaggtta agacagtgat aacatgccat
       61 ggatgggttg aatataactt aaaaaagaaa ttcttgactt attttgattt ttggacatat
      121 tctatgggag atgcttttat ttgtgtatct gaaactatga aaaaaagatt ggagagtata
      181 ataaaaaata agaagatagt tgcaataaat aacggaatta atgtatcaaa tagcgattta
      241 gatgtagtag gtgttcaaga ctttaaaaaa gaattttgta ttccaaataa caaaaaaatc
      301 atttgttatg ttggaaggtt ggatccagaa aaaaggccgg atagattcct tgaatttgca
      361 gaaaaattat ttttagtcag agaagatgtg atttttatta tggctggaaa tggtagtatg
      421 tgggctgctt tgaaagaaaa aatttgctat ttgaaatgta gagataattt caggttactt
      481 ggtgaaatct atccagtact atagtttacc aaatatcgga tttattgtat attccttctg
      541 atacagaagg aatacctatg tgtgttttag agtcaatgtc acaaggaact ccggttttag
      601 ctagtaatgt tggcgggtta agtgaaatta ttgaacatag ggttgatgga tttttatttg
      661 agaaggaaga tgttgaggga gtgtgtgctt gtgctaattt tttactcaat gattctgagt
      721 atttgaaata tataggtgag aatagtaaat caaaaataag aaaacatttt tctgtgcaaa
      781 aaatgtttgt agaaaccatg agagtatatg atgaattatt agagaagagt agtcatggat
      841 aggaatatag atcaagaatt agtaagtatt ataataccaa cacataatag gtatgaatct
      901 ctgattagag ctgtgaaaag ttgtttacat caaagttata aaaatatcga agttat
//
LOCUS       DAVKZI010000118          941 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVKZI010000118 DAVKZI010000000
VERSION     DAVKZI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.119"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..728)
                     /locus_tag="VXB18_002225"
     CDS             complement(<1..728)
                     /locus_tag="VXB18_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383328.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSDVDLDIFYKV"
BASE COUNT          361 a          161 c          122 g          297 t
ORIGIN      
        1 aaaactttat aaaaaatatc taagtcaaca tcactctgat tctgaagcaa gtaggagtca
       61 agcaaatttt caaaaatagc taacaatatg attggtgtaa ggtttttgta ttcacatgtc
      121 aagtattccg agtatcgtgc agatgatatt tcttttatat aactttttga aagcaagatt
      181 ttttcaaatt catcatctat tattaatctt ctatttccaa tccaagcggt attaccaccc
      241 aaataagatt gtacaaatag caatatataa gaaaacatga acgtaaatac tgaaaaaggt
      301 agaattctat gcgtaaaaaa atagacgata atggtagcca ggagtaaaga tatctctcgt
      361 gacaatcgaa ttcttttcag catctttttt aacagtccgt aaggttgtcc ttggcaatat
      421 tcttgaacta aattaatcgg aatgacatct ctcaccattt ctggaaagta gagtaagttt
      481 ataggttgaa atctccagct cccatcataa gtaaatggat atagaaccaa atacttaaaa
      541 gatttttttc ttataaactt aattatcaca atatgaatga ctgttgcaat gaagtatatt
      601 aaatataaaa gtaaaaccgc catcaatata cttacaaaaa tccccttgga atcaatcaat
      661 ggaaaataaa atattgcaac tagaagcgaa taaagtcccg ctaataaata tttctgatca
      721 tctttcattc aaaacaccat attatttact aagaatgcat caatacaata gagcaactct
      781 gtaagtcaat atttgataaa gcaaagcttt aaacccttcc ccagacgtta gcttttattc
      841 aacccactac agttgacaag gagcccaaat tattgataaa aactttagtc atcatcgtct
      901 ctataaaaat attttctata cactcttgat aataccaaaa t
//
LOCUS       DAVKZI010000119          934 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVKZI010000119 DAVKZI010000000
VERSION     DAVKZI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..934
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.120"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>934
                     /locus_tag="VXB18_002226"
     CDS             <1..>934
                     /locus_tag="VXB18_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383329.1"
                     /translation="MLFVYILQMTNRLKDSSIILISDRVIYIFLLFLFIIFKWHEYKV
                     MIWADVLGRTFSLLLSFWTCKDIVFQSLSEFILDLRESFDNIRVGINLMLSNIASSMI
                     IGIVRMGIQWNWNIETFGKVSLMLSISNLLMTFINAIGLVVFPLLKRTKTENLSKIYS
                     NLRNVLMLIMFAILLFYYPLKIILDLWLPAYRDALIFMALIFPMSIYEGKMALVINTY
                     LKALRMERDILKINTLIMLFSMLVTLITTLLLNNLELTVISIVVLLALRSIIAELILS
                     KKLDISVEQDIVLELLMTIIFISSSWYLPIWLAV"
BASE COUNT          280 a          118 c          162 g          374 t
ORIGIN      
        1 gaatgttatt tgtttatatt ttgcagatga caaatcgatt aaaggatagc tctataattc
       61 tgataagtga tcgcgttata tatatttttc ttttatttct gtttattata tttaaatggc
      121 atgaatacaa ggtaatgatt tgggcggatg ttttaggaag gacattttct ctcctacttt
      181 ctttttggac ttgtaaagat attgtttttc aatccttatc cgagttcata ttggatctga
      241 gagagtcttt tgacaatatc cgtgttggaa tcaacttaat gttatccaat attgcaagta
      301 gtatgattat tggtattgtt cgaatgggaa ttcaatggaa ttggaatatc gaaacattcg
      361 ggaaagtatc actgatgcta agcatctcta atttattaat gacttttatt aatgcgattg
      421 gtttagttgt ctttcctttg ttaaaacgga caaaaacgga aaatttatct aaaatttatt
      481 ccaacttaag aaatgttttg atgctgatca tgtttgcaat attgctcttt tattatcctt
      541 taaaaattat tctagatctt tggttgccag cttatcggga tgcgttgatt tttatggctc
      601 ttatttttcc tatgtcaatt tatgaaggga agatggcctt ggtgattaat acatatttaa
      661 aggcgctaag gatggaaaga gatattctca aaataaatac tttgattatg ttgttcagta
      721 tgttagttac cctaataact actctattat taaataattt agagctaacg gttatatcta
      781 tagttgtttt gctagcttta cgtagtataa tagcagaact aattctatct aaaaaacttg
      841 atatatcagt tgagcaagac attgtgttag aattacttat gacaattata tttatttctt
      901 caagttggta cttaccgatt tggctcgcag taat
//
LOCUS       DAVKZI010000120          903 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVKZI010000120 DAVKZI010000000
VERSION     DAVKZI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.121"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            84..266
                     /locus_tag="VXB18_002227"
     CDS             84..266
                     /locus_tag="VXB18_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0383330.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            276..626
                     /locus_tag="VXB18_002228"
     CDS             276..626
                     /locus_tag="VXB18_002228"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0383331.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKQG"
     gene            634..>903
                     /locus_tag="VXB18_002229"
     CDS             634..>903
                     /locus_tag="VXB18_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0383332.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHI"
BASE COUNT          372 a          115 c          150 g          266 t
ORIGIN      
        1 cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac ttaaacatca
       61 aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat ttgatataca
      121 gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa aataaaggtc
      181 gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta tcctttaacg
      241 aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa agtacaaaac
      301 ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa ataaaatggt
      361 gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata aaagttattc
      421 ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga actcaagcta
      481 taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa tattatggag
      541 attctgcctg ggaacattta agagcagtga ccggtattga tttacttagt attctaacag
      601 atattgcaaa taaaaaacag gggtaaaatc aaaatgacag tattaaaagg agataactta
      661 gaaatattaa aaactattga atcctcaagt attgatttaa tctatatgga ccctcctttc
      721 tttacacaga aaacccaaaa attatctaat aacaaaaata ttatgtattc attcgaagat
      781 acgtggactt cgattgagga ttacaaagaa tttttgtctg taagattaga agaatgcaaa
      841 agagtgctaa aaaatagtgg cagtattttc gttcattgtg ataaaattgc aaatcatcat
      901 att
//
LOCUS       DAVKZI010000121          581 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVKZI010000121 DAVKZI010000000
VERSION     DAVKZI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.122"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
BASE COUNT          220 a          105 c           67 g          189 t
ORIGIN      
        1 ttattatatc caatcactag tccaataatt ggactagtga ttggatataa taaaaataac
       61 aaaaaatgaa tttcaccaat tcctgcaaaa aaatgtttca tagctatagt tttacgccca
      121 taaataccca tcaaatttac cgtctacgat atctaaacca tatgcaatgg ctcctcctaa
      181 tgagaagact tcagcaacag tagccgcaat attaagagca ttagtaatag ttgccatact
      241 aactccacca atatatcttg ttataacact tagttaccta gataagatat cctttagctt
      301 gcttccaaaa tttaagtctg cacctataat atgagttcat attagtactg ctaaatccta
      361 tctatagtaa tgtcaaacac ctaaataaag tcatctctcc aattcattca agaaatgaag
      421 aaaggcaaaa aatctttaaa ataagaaaaa tgcatattat caggtgttca aaaatattga
      481 tgatatacgt tatatagata gaaagattta ctcaatctca ttttcaaatt gagttttttc
      541 ccagcctcgt ttttaattta tatcttcaat agaatctaat g
//
LOCUS       DAVKZI010000122          529 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVKZI010000122 DAVKZI010000000
VERSION     DAVKZI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.123"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>529
                     /locus_tag="VXB18_002230"
     CDS             <1..>529
                     /locus_tag="VXB18_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV0383333.1"
                     /translation="KMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLAIS
                     TSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQA
                     VIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSR
                     FRVQIMNQFERKSHE"
BASE COUNT          159 a          109 c           91 g          170 t
ORIGIN      
        1 caaaaatgat ggttgctgag actcccctgg taaagaaaaa tcaccaaatc cctcgtatca
       61 tcaaccaaaa aattgctcaa aagttaattg aaaaaatttc tatgactgat attgcccatc
      121 agctggccat ttcaacttca actgtcattc gcaagctcaa tgactttcac tttgagcatg
      181 atttttctcg gcttccaaag attatgtctt gggatgagta tgccttcact aagggaaaga
      241 tgagtttcat tgcgcaagat tttgataatc ttaatattat cactgttctt gaaggcagaa
      301 cacaagctgt catccgaaat cactttcttc gctacgatag agccgttcgt tgtcaagtga
      361 aaatcattac gatggatatg tttagtcctt actatgactt ggctaaacag ctttttccgt
      421 gtgctaaaat cgttctagat cgtttccata ttatccaaca tctcagccgt gccatgagtc
      481 gttttcgtgt tcaaattatg aatcagtttg aacgaaaatc tcatgaata
//
LOCUS       DAVKZI010000123          460 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVKZI010000123 DAVKZI010000000
VERSION     DAVKZI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.124"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..397)
                     /locus_tag="VXB18_002231"
     CDS             complement(<1..397)
                     /locus_tag="VXB18_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0383334.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIP"
BASE COUNT          153 a           79 c           56 g          172 t
ORIGIN      
        1 tcggaatatt atcttcaata tcaacgaatc tttttggaga aaaacctaag caaactataa
       61 attgaggatt ttcacttaaa attgcagata tcttattttt aatctctgag aatttatgta
      121 agtaaacata ttctacatct aaagataact gatcaatttc tgcaaaatac tcagcatact
      181 ttttgcgtgc attattaaat aacaagaaaa aacatttact agaagcgcct tttcgaagaa
      241 actgagcttg agaattcata ttataaccca attttttcgc agtctcttct actaacttta
      301 ttttagctgc tgagacatta ccttttttat ttaaaacgtt tgaaactgtc ccatgtgaga
      361 ctccagacac tcttgcaata tcttttattg taaccataat taacctctag tttaagagat
      421 cttttagtat atttgagatc tctttacgct ctttaatttg
//
LOCUS       DAVKZI010000124          412 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVKZI010000124 DAVKZI010000000
VERSION     DAVKZI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.denovo.125"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>412
                     /locus_tag="VXB18_002232"
     CDS             <1..>412
                     /locus_tag="VXB18_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0383335.1"
                     /translation="LNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRA
                     HGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPK
                     LYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQD"
BASE COUNT          113 a           97 c           74 g          128 t
ORIGIN      
        1 ctcaaccttg aattggtcga attcttttta cagtttcacc agctaaacca actcattgta
       61 gatatcgatt ctacccattt cacaacttat ggcaagcaag aaggtgttgc ttataacgcc
      121 cactatcgtg ctcatggcta tcatcctctt tatgctttcg aggggaagac aggttattgt
      181 ttcaatgccc agcttcgtcc tggtaatcgt tattgttctg aagaggcaga cagctttatc
      241 acacctgttt tagaacggtt taatcaactt ctctttcgaa tggatagtgg ctttgcgacc
      301 ccaaaattat acgatttaat tgaaaaaaca gggcaatact acctcataaa actcaagaaa
      361 aatactgttc tgagccgtct tggagacctt tccctccctt gcccacagga tg
//
LOCUS       DAVKZI010000125        26920 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00038917
            SAMN33606648-rid17948123.guided.028, whole genome shotgun sequence.
ACCESSION   DAVKZI010000125 DAVKZI010000000
VERSION     DAVKZI010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606648
            Sequence Read Archive: SRR23726175
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722052.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722052.1
            Genome Coverage       :: 284x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,261
            CDSs (total)                      :: 2,212
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 70 of 151
            Pseudo Genes (incomplete)         :: 78 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 33 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606648-rid17948123.guided.028"
                     /strain="AUSMDU00038917"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            62..271
                     /locus_tag="VXB18_002233"
     CDS             62..271
                     /locus_tag="VXB18_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0383336.1"
                     /translation="MKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLP
                     DIKIKLPIDSRGTPDWNYMERYRDR"
     gene            237..551
                     /locus_tag="VXB18_002234"
     CDS             237..551
                     /locus_tag="VXB18_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383337.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1225..1410
                     /locus_tag="VXB18_002235"
     CDS             1225..1410
                     /locus_tag="VXB18_002235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383338.1"
                     /translation="MKKKGGMHVDNDWNGLAELFANLITKYAGVLDLDNLPDPTPAKN
                     QEMKNSFDMAKTQIETD"
     gene            1502..3181
                     /locus_tag="VXB18_002236"
     CDS             1502..3181
                     /locus_tag="VXB18_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0383339.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            3449..4015
                     /locus_tag="VXB18_002237"
     CDS             3449..4015
                     /locus_tag="VXB18_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383340.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4336..4524
                     /locus_tag="VXB18_002238"
     CDS             4336..4524
                     /locus_tag="VXB18_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0383341.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4586..5344
                     /locus_tag="VXB18_002239"
     CDS             4586..5344
                     /locus_tag="VXB18_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0383342.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5402..6256
                     /locus_tag="VXB18_002240"
     CDS             5402..6256
                     /locus_tag="VXB18_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0383343.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6368..7252
                     /locus_tag="VXB18_002241"
     CDS             6368..7252
                     /locus_tag="VXB18_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0383344.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7415..9154
                     /locus_tag="VXB18_002242"
     CDS             7415..9154
                     /locus_tag="VXB18_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0383345.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKIPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9429..9731
                     /locus_tag="VXB18_002243"
     CDS             9429..9731
                     /locus_tag="VXB18_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383346.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9787..10214
                     /locus_tag="VXB18_002244"
                     /pseudo
     CDS             9787..10214
                     /locus_tag="VXB18_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            10293..10880
                     /locus_tag="VXB18_002245"
     CDS             10293..10880
                     /locus_tag="VXB18_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0383347.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            11129..11418
                     /locus_tag="VXB18_002246"
                     /pseudo
     CDS             11129..11418
                     /locus_tag="VXB18_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821711.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            11523..11825
                     /locus_tag="VXB18_002247"
                     /pseudo
     CDS             11523..11825
                     /locus_tag="VXB18_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            11981..13210
                     /locus_tag="VXB18_002248"
     CDS             11981..13210
                     /locus_tag="VXB18_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0383348.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            13230..15926
                     /gene="ppc"
                     /locus_tag="VXB18_002249"
     CDS             13230..15926
                     /gene="ppc"
                     /locus_tag="VXB18_002249"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0383349.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDKEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    16009..16226
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16339..17343
                     /locus_tag="VXB18_002250"
     CDS             16339..17343
                     /locus_tag="VXB18_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0383350.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            17412..18278
                     /locus_tag="VXB18_002251"
     CDS             17412..18278
                     /locus_tag="VXB18_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0383351.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPIF
                     KQTILKGAKLSK"
     gene            18275..19033
                     /locus_tag="VXB18_002252"
     CDS             18275..19033
                     /locus_tag="VXB18_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0383352.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMGLTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            19123..20883
                     /gene="dnaG"
                     /locus_tag="VXB18_002253"
     CDS             19123..20883
                     /gene="dnaG"
                     /locus_tag="VXB18_002253"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0383353.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLTQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            20886..21995
                     /gene="rpoD"
                     /locus_tag="VXB18_002254"
     CDS             20886..21995
                     /gene="rpoD"
                     /locus_tag="VXB18_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0383354.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            22009..22338
                     /locus_tag="VXB18_002255"
     CDS             22009..22338
                     /locus_tag="VXB18_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0383355.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            22453..23496
                     /gene="cpoA"
                     /locus_tag="VXB18_002256"
     CDS             22453..23496
                     /gene="cpoA"
                     /locus_tag="VXB18_002256"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0383356.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            23512..24837
                     /locus_tag="VXB18_002257"
     CDS             23512..24837
                     /locus_tag="VXB18_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0383357.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            24868..25044
                     /locus_tag="VXB18_002258"
     CDS             24868..25044
                     /locus_tag="VXB18_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0383358.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            25103..25237
                     /locus_tag="VXB18_002259"
     CDS             25103..25237
                     /locus_tag="VXB18_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0383359.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            25301..26611
                     /gene="obgE"
                     /locus_tag="VXB18_002260"
     CDS             25301..26611
                     /gene="obgE"
                     /locus_tag="VXB18_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0383360.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENIEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            26621..26779
                     /locus_tag="VXB18_002261"
     CDS             26621..26779
                     /locus_tag="VXB18_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0383361.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         8858 a         4270 c         5849 g         7943 t
ORIGIN      
        1 ttttatatct gtttcatttt taggagcagt cttttatcat aaatataaag caagcctaga
       61 tatgaaaatt cattgtttaa aattaaaaaa taaagaattg aataaagaag tagcattcta
      121 tttaacttca attattaggc aagctttaaa aaatactgaa tataaagatc aaatatctag
      181 cacagtattg ccagatatca aaattaaatt accgatagac agtagaggta ctccagattg
      241 gaattacatg gaaagatata gagatagata aagagagaga gggagagata gataaaaagt
      301 ccacccccat tttttatgga gaattcaaaa atgtaaggtt aagcaaagaa gaatataaaa
      361 atctaaaaga aaaattaaac tcacacacag atataatgat aaataaacta tccagataca
      421 tggaaagcag tggtaagacc tatcaaaacc actatgtgac aatcttaaaa tggtatgaag
      481 aagataaaga caaactaaga cagaaaggtt taaataaaaa aatgaattat gatgtaggag
      541 aatctttata gataaaaaga ggtggaaagg cactattaaa gactttaagt ctaaaaaggt
      601 atcaaagtat gccagagata aaaaaatata aatatgacac tttaaaggcg attagaaaat
      661 taaagaaatg ctagaagact tttagatgac agttaccaag agggtctaat tttcactgct
      721 acttatgcag tgggaattgg acctttttat ataagcaaat tctatttcaa aattggttac
      781 caagaaagac ttcttttcac tgttaagtat aagagggtaa tttatagaat tttgttacat
      841 caagataaat attttatgat ggtcaaattt taaaaagatt aataactctc gataaatttt
      901 gaaccttaac aattgaatag accaagacaa gacgttaatt atttttggag cgtaataacc
      961 tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa agttctgcta agcaaaaaga
     1021 aagtgagcga taagtaagag tttgaatata gggagggata ccctatccgc tatgaagaaa
     1081 atgaggataa tgatacttct ttagtgaaag ccggctcatc ttaacagggg cggtggtgag
     1141 attccaatgt tgctgatcct aagcacccgt taatgtcatg aaacttagtt agatgagaaa
     1201 gttatagatt gattatataa gagtttgaag aaaaaagggg ggatgcatgt ggataatgac
     1261 tggaatggac tggctgagtt gtttgcgaat ctaattacaa agtatgctgg tgttttagat
     1321 ttggataatc tgccagatcc aacgccagca aaaaatcaag agatgaaaaa tagttttgac
     1381 atggcaaaaa cacaaattga gacggactaa taaaagtgtt ataatatact tgaaatgata
     1441 gtccaaactt aaattaaaaa aattatatat gatatagaaa aattatattg agattaatac
     1501 tatgtcaaaa gaaaaaataa aagtatacct ctatacacga gtatctacgt caatacagat
     1561 agaggggtat tcgttagagg cacaaaaatc acgaatgaaa gcttttgcta tttacaatga
     1621 ttatgaaatt gttggagagt atgaagatgc cgggaagtct ggcaagtcta ttgaaggtag
     1681 aatacagttc aatcgaatga tggaagatat aaaatctgga aaagatggag tatcttttgt
     1741 tcttgtgttt aagttatcaa gatttgcaag aaatgccgct gatgttcttt ctacacttca
     1801 gataatgcag gattatggag ttaatcttat ctgcgttgaa gatggcattg attcatctaa
     1861 agatgctggg aaactaatga tttctgtttt atcagctgtg gctgaaatag aaagagaaaa
     1921 catccgtatt caaacaatgg aagatcgcat tcaaaaagca agggaaggaa aatggaatgg
     1981 tggctttgct ccgtatggat ataaacttga agacggcaag ctgtttataa atgaggaaga
     2041 ggcagttgca ataagaacga ttttcgacca gtatgtaaat actacgatag gagccaatgg
     2101 gatatctaaa tacttagaga atcatggaat tagaaaaatc ccaagacaga atggtaagaa
     2161 tcctttgttt gatgcaggtc ttataagaaa gatattaaag aatcctgtat ataatgggaa
     2221 aatagcattt ggaagaagaa ctttagaaaa agttcatggt acaagaaatg aatataagca
     2281 ggttgaacaa gatgaatatc taatatctga agggatacat gaagctatag tttccgatga
     2341 agtttggcaa gctgctcagg ttaagctaaa atctcaagca aagaaatatg agcatgtgaa
     2401 taaaggaaaa gatacacgca cacacttgct ttctggaatt gtaaaatgcc cgatatgtgg
     2461 agtgggaatg tttgggaaca agtgtatcaa gaaaaagaaa gatggcacaa agtataaaga
     2521 tttttattac tatggttgta aacataggca gatgataaga ggtcataagt gtacattcag
     2581 taagcaaatt agagaagaat tgttagatga tgctgttgca gaggtgattg tcaagatagt
     2641 aagtaatccg aaatttgctt ctatgatgca agaaaaaatc aacatgaagg tggatacctc
     2701 tgaaatagaa aaagaaatag ataattacca aaaggaattg agaaagagtc attctacaaa
     2761 gtttaagcta attgaggaaa tagataattt agatgttgaa gataagcact ataagagaag
     2821 gaaacaggat ttagatgata gactatatcg tatgtatgac aaaatagatg aattagaatc
     2881 atcactaatt gatgcgaaag caaagaaaca gactattgaa gctgaaaaac ttacaggaga
     2941 taacatatat aaggttctga tctattttga taagctctat aaagtcatga atgatgtaga
     3001 gcgtaggcag ttaatttcag ctttgatttc tgaaattcaa gtttatgaag aaaaacaatc
     3061 taacggacaa tggctaaaat ccattacttt taaactacca attatagaag aaaatctcaa
     3121 cataggtttg gataatgatg aacaagttga atgtgtaagt ttattagaga aacgtagtta
     3181 atcctcaaaa ggttccccaa accttttgag tcccactgac gcatcacgct gaggcggtat
     3241 cactgcttgt acgagttgaa gcatcagcga agtaaaagta gatgttcagc caatgcgacg
     3301 aggtgagacc gaaggtcgat aaggtgtgtt ctgggtatag gactcgtaaa gtaagtagga
     3361 aatatgatga gatgatacag agagcctgaa ttggtcaggt gacgtgctta tttacattag
     3421 cctgataatg aaaatggaga gattatcgat ggttatattg gaattgtacc aaaatgatta
     3481 ttctaaagat ttagtagcat ttgattccat agaagatggg aaagcctttg tagctcaaat
     3541 cccgggatac actctggaaa cagaagatgg ttttgaagtg gagtatttta atcctaaaaa
     3601 cataccggat tatatggaaa ttatttttaa cggaaatatt gttcctttat ctaaatttat
     3661 gttcgatcct gaggaaaatg taaacattat ttggaaagag atttcaaatt tatccctcaa
     3721 aaatgataga gtgatcgaag gatattcaaa aattgatgca tatgtcgtta acaaccatga
     3781 agttaaagcc tatgtcgaaa caagagaaac gaactatcgt aaagcaaaag acttcttaga
     3841 aagccgcgga tatgaaatcg acagaagctt tttcggaagt gaagacggtg aagcgattct
     3901 ttacagaaaa aaagggatcg aagtttggca tttcttgtgt cacttagacc caatgtttgt
     3961 agagattgaa gatgtagaag gatatgttaa agaagaagtt ggagagattc aatagtcaac
     4021 caaagttcct tgtgagtata tacctttgct agtaaaagag tcaaaacgtt ataacgaagg
     4081 ggggaagaaa acccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag
     4141 ccgctcataa tttatactag atttgataac tgatttgaga cagattttat ttctataaat
     4201 attgtgaaaa ttttttaata ccaaagattt aaagttactg tgttaaaaat cctctccact
     4261 tttaaactaa tgtattataa aagccagttg acacaagtgt tacacctgtg atagaattaa
     4321 cttgaggtga tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa
     4381 aatctagaga aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta
     4441 acaaagtccc aggttattga attactccta aataccgttg attatttcga tgatattatg
     4501 ggggctattt actcaaaaaa ataagagcaa aattgctatt attttttaca aattggtgta
     4561 acactagtga tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag
     4621 tgaggtttca attaataaat acaatgctca agtaggtgcc tacttacaag gagaagaagc
     4681 tgttttatat caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga
     4741 ttatataatg gagactagag cattactaaa aatgatgggc ttaaacgttc cggttcatga
     4801 ctatcctatt gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga
     4861 gattgtgaat atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt
     4921 ctttactgga agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga
     4981 ctatcctata tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt
     5041 agatggtcgc gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc
     5101 aagtgtaatt gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga
     5161 tatcggtgtt actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt
     5221 gggaaattat ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga
     5281 aatggtaaaa ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttgtttt
     5341 ctaaaataaa tatggtatat aaccaatata aaaagcatca aaatgaacaa ggaggaatct
     5401 gatgcttgga gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa
     5461 aacaaaggac tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac
     5521 ctgtgctgtt gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat
     5581 gaagaaatat ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct
     5641 aaacagcgat aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc
     5701 tccatgtgct tggatcatgg actgtggttt ttatgcgaaa actggtatgt ggccatcatc
     5761 tagaggactt acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg
     5821 cgctatggct acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag
     5881 agagtacgag caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta
     5941 tatagaaaaa gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta
     6001 tcgttttaac gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag
     6061 tagagacttc gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct
     6121 cgcagcaatc acttgtagca tagcagaggc agcttacggt attcctgatt ggatcaagga
     6181 taaggcctat tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag
     6241 aataaaagcg tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata
     6301 ataggattac atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat
     6361 aaaatcaatg aaaaaagcaa tggtaattat caaccctact tctggtggcg agaaggcttt
     6421 ggattacaaa gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa
     6481 aattaccgaa aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta
     6541 tgatgcagtg gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga
     6601 tgagagagac tacattccta agttagggat tatcccaggc ggtacgggta acctcattac
     6661 aaaacttttg gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt
     6721 aaccaataag attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat
     6781 cggttctctg cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat
     6841 tttaacctat gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa
     6901 ggttgagaca gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac
     6961 aaattacttc gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt
     7021 gattctgaaa gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg
     7081 ggatgttgtc gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc
     7141 agatagtgaa ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat
     7201 caaagtccta gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga
     7261 gaaagccttt tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat
     7321 tccttgcaaa tagttcacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg
     7381 taaaatttga atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag
     7441 gcctgagtcg gagtatgcct atctttataa ggataagaaa ctccatattc gaattcgaac
     7501 taagaaaggg gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga
     7561 ggagttttat caggatacaa aagaaatggt caagataact tctggtacct tatttgacca
     7621 ttggcaggtt gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga
     7681 tacagaaggt caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa
     7741 tcttcatgca attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa
     7801 gattcctgac tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa
     7861 tggcaatgct ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa
     7921 gagcgatgat ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca
     7981 agacttgggt attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa
     8041 gtacaatacg acagattact ttgaaattga ccgtcatttt ggagacaagg agacctttcg
     8101 ggaactggtg gatcaagcgc atcatcgtgg catgaaagtc atgctggatg cggtatttaa
     8161 tcatattggt tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggtg aacagtctgc
     8221 ttataaggat tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa
     8281 gagagactta ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc
     8341 caatccagag gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa
     8401 tatcgatgct tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt
     8461 tcgtaaggca gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac
     8521 atctcagcct tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga
     8581 tagtatcaag gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat
     8641 caatggagag tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga
     8701 ttcacatgat acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc
     8761 agccttagcc tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagtt
     8821 agccttgact ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc
     8881 aagtgacaat gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc
     8941 agtaatcatt tcgcatggca agtatagcct tcaagaaatc aaatctgatc tagtagctct
     9001 ggaatggaaa tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta
     9061 tcttttagag aaagaagcag tagcactagc aagcaattgc caagaattgg agaatcagct
     9121 tgtcatctct ccagatggat ttgtgatttt ctaaaaacta gttgatgaag attatggtac
     9181 atttcatatc ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa
     9241 tgaattgtag aggacatgaa acaagacaaa gaattgttag agattttgaa gtttagccta
     9301 aagcacatat taagctgtta gcaaatcaac aaaaacatag tgatgcagga gcaactattg
     9361 aagatgaata ttatgtattt atcgctgaga gtaaaattga tgacaagaag gaagttattc
     9421 agtgttgcat gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc
     9481 tttttaatcc gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag
     9541 ggagtggaaa tttacaacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta
     9601 taatgtggtt gattatttta tggaatgcta agccggatac acctttattt aattttaaag
     9661 acgaagtaat taagtataaa acatatgagc cttttgaaag cagtataaaa ttggtatcaa
     9721 tcaatgagta acaaagtatc agcatgattc gaaacattta cttgtaattt gcggaggaac
     9781 atcaatatgg atggaataac aaaagatttt ataaaaacgg ctaaactaat gaaacaatta
     9841 tggccccaat tgaccgataa agaagctatt gatgaagtaa aaaatatacg aatggcaaaa
     9901 atactgcaat ctttactgaa gttgaaggtg acacaattgt aggtctagca ctatgttcac
     9961 tcagatttga ttatgttgaa ggttgtaaat atagtcctgt tggattctta gaagggatta
    10021 ttgttgacga ggaatatcgt ttaaaggata ttgctaaaaa tctctgtaca aaatgtgagg
    10081 aatgtgcgaa aaataaagga tgtaaggaat ttgcaagtga ctgtacttta acgaatacgg
    10141 attctataag atttcatctc aatattggat ttcaggaggc aaatagaatt attcatttta
    10201 agaaaaaatt ataatttaga aacgtgaata aacttgttta aactttatgt atctttagaa
    10261 agtgtgttaa cttgaaagaa caaatttttt tgatgggtgg gaatccccca atgaagaaat
    10321 atagtattgt tgataaaatt gtattatcaa ccaagattaa aagaattatc atttttacag
    10381 tttttcgaga aaattgggaa ccgtacatga aaaagtacac ggaagttttt caaagtcaat
    10441 ttcctaatct aaacattgat tacttgctcc tggacactga gcagattgat cttgatagct
    10501 atctagatgc tgacataatt atcatcggtg gtggaaatac ggaaaaatat attgctactt
    10561 atgttaatca ggagttcaaa agttatatcg atcatatgct taataaagag gcaaaaatta
    10621 taggattttc tgcaggagcc ctactattag gagaaaaagt ctatgtctca cctaatgata
    10681 attcagatca tcagataaag ataaaaaatg gattaggact ctttagtcag tttttaatta
    10741 gtgtccatta tgattcctgg aatgataaag caaataagga tagagctgaa gaactcgtta
    10801 atgttcccat aattccacta aatgatcatt cttgtcttgt attggataaa cttggaaaca
    10861 tcatagagaa aattgactaa ctttcataat gtaaaaatgg atctaggaaa taaaagtgta
    10921 gacgaactgg ataggttact agtgaaaact gcaaaaagtg ttgtaaagtg aatcggagtg
    10981 tgcttgatgg attttagtag taagatagcc ataaataaag gctggtcaga tgataaaaaa
    11041 tattgtgtga cagatcaaaa tcagtaaaaa tatttcttgc gtgtttctga taagtcgaag
    11101 ttagattata aaaaaatttg aatttgatat gatggagaaa gtagcttctc ttggagttcc
    11161 gatgtgtaaa ccaattagca ttgaactctg cgatgacgaa gtacattctt tacacgaatg
    11221 gatagacgga agagatgcaa tagatagcat tttagcttat tcagaaaacc aacaatacac
    11281 atatggtgta gaagcaggaa agatacaaag atacttagaa agattcatac aattcctgct
    11341 acagaagttt gtgaagattg ggaaattttt tttaatctaa aaattgatga taaaatctcc
    11401 aacgaaatga tatggtaagt ccgaaacgct cagtgtgtaa gcttgttgct aaaagcgtaa
    11461 aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa tacaataaaa
    11521 ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagatc cttgtaggtg
    11581 ttcagcgcac gacttttgaa gagatgttag ctgtgttaaa aacagcttat caacgtaaac
    11641 gcgcaaaagg tggacgaaaa agcaaattaa gcctagacga tctccttatg gtaactattc
    11701 aatacatgcg agaatagagc acttatgaac aaattgcggc tgattttggc attcacgaaa
    11761 gcaacttaat tcgtcggagt caatgggttg aagcaactct tattcaaaat ggttttacga
    11821 tttcaaattc tgccttaatt ctgtaaaaac agtaaaattc gaaggattgt aaggtaagag
    11881 tttttttctt tctgaaaaaa tggtataata gcaatcaaaa ctagaaaata aaacggaatt
    11941 tggaacagat ttgtctgtat cctagtagag tggtgatact atgaagatta gtaagaggca
    12001 cttattaaat tattccatct tgattcccta cttgctttta tctattttgg gcttgattgt
    12061 ggtctattcg accaccagtg ctattttaat tgaagaaggc aagagcgcct tgcagttggt
    12121 tcgaaaccaa ggaatctttt ggattgttag tttgatactg attgccttaa tttataaatt
    12181 gagactagat tttttgagaa atgagcgact aatcatttta gttatattaa tagaaatgct
    12241 tttattgttc ttggctcgtt ttattggtat ttcagtaaac ggggcatacg gttggatttc
    12301 ggttgcagga gtaactattc agccagctga gtacttaaaa atcattatta tttggtattt
    12361 agctcaccga ttctccaaac agcaagaaga aatagctact tatgattttc aagttttgac
    12421 tcaaaatcaa tggcttcccc gtgcttttaa tgattggcga ttcgttctcc tagttctgat
    12481 tggaagtttg ggaattttcc ctgatttagg aaatgcgact attttagtct tggtttcctt
    12541 gattatgtat acagttagtg gaatcgctta tcgctggttt tcaaccattc tggcgctcgt
    12601 atctgccact tctgtctttg tcttgaccac tatcagccta atcggtgttg agaccttttc
    12661 aaaaattcca gtatttggct atgtagccaa gcgctttagt gcctttttta atccttttgc
    12721 cgatcgtgct gatgcaggtc accagttagc taattcttat tttgccatgg tcaatggtgg
    12781 ttggtttggt ctaggtcttg gaaactcgat tgaaaaacga ggttatttgc cagaagctca
    12841 tacagacttt gtcttttcta tcgtgattga agaatttggc tttgttggtg ccagtcttat
    12901 tttagctctc ttgtttttca tgattttgcg gattatcttg gtcggtatcc gagcggagaa
    12961 tcctttcaat gccatggttg cactcggtgt cggagggatg atgttggttc aggtatttgt
    13021 caatatcgga gggatttcgg gcttgattcc atctacagga gtgactttcc ctttcttatc
    13081 ccagggtgga aatagtcttc tagtcttatc agtggcagta gcctttgtct taaatattga
    13141 tgccagtgaa aaacgcgcta agttgtaccg agaattggaa aatcaaccaa tgaaccttct
    13201 gttgaagtag gataaagaaa ggatagttta tgtctcttca aaaattagaa aattatagta
    13261 ataaaagtgt tgtgcaagaa gaagtcttga ttctaacaga attactggaa gatattacta
    13321 aaaatatgct tgccccagag acctttgaaa aaataataca gttgaaagaa ttatcaacgc
    13381 aggaagatta tcaaggtcta aaccgtctag tgactagctt atcaaatgat gaaatggtct
    13441 atatttcacg ctatttctct atcttgcctc ttttgattaa tatttcagag gatgtggatt
    13501 tagcttatga aatcaatcat caaaataata ttgatcagga ctatttaggt aaattatcta
    13561 caacgattaa attggtagca gaaaaggaaa atgccgttga gatcctagaa cacttgaatg
    13621 ttgtccctgt tttgacagcc catccaacac aagtgcaacg caaaagtatg ttggatttaa
    13681 caaatcatat tcatagtctt ttgcgtaaat accgtgatgt taagttgggg ttgatcaata
    13741 aagataaatg gtacaatgat ttgcgtcgtt acatcgaaat tatcatgcag acagacatga
    13801 ttcgtgagaa aaaattaaaa gtgactaacg aaatcacgaa tgctatggaa tattataaca
    13861 gctccttttt gaaagctgta cctcatttga cgacggagta taagcgctta gcgcaagcgc
    13921 atggtctgaa tttaaaacag gctaaaccaa tcaccatggg tatgtggata ggtggtgacc
    13981 gtgatggaaa tccatttgtt acagcaaaga ccttgaagca gtctgcactc actcagtgtg
    14041 aagtcatcat gaactactat gataaaaaga tttaccaact ttatcgtgaa ttttctcttt
    14101 caactagcat tgtcaacgtc agcaagcaag tcagagaaat ggctcgtcaa tccaaggata
    14161 actcgattta ccgcgaaaaa gagctttacc gtcgtgcctt gtttgatatt caatcaaaaa
    14221 ttcaggcaac taaaacctat ctgattgagg ataaagaagt tgggactcgt tatgaaaccg
    14281 ccaatgattt ctacaaggat ttgattgcca ttcgagattc tctactagaa aataagggcg
    14341 agtccttgat ttcaggtgat tttgtggaat tattgcaggc agtagagata tttggttttt
    14401 acttagcatc aattgatatg cgacaagact ctagcgtcta tgaagcctgt gtggcagaac
    14461 tcttgaaatc agcaggaatt cattctcgtt atagcgagtt gagcgaagaa gaaaagtgtg
    14521 accttctctt gaaagaatta gaagaagatc cccgaattct ttctgcgact cacgcagaaa
    14581 aatcagaatt attagcaaaa gaattagcta tttttaagac ggctcgtgtt ttgaaagata
    14641 agttgggaga tgatgtcatc cgtcagacca tcatttcaca tgcaaccagc ctttctgata
    14701 tgctagaatt agctattctg ttaaaagaag taggactggt ggatacggaa agggcgcgtg
    14761 ttcagattgt tccccttttt gaaacaattg aagacttgga tcattcagag gaaacaatga
    14821 gaaaatatct ttctcttagc cttgccaaaa aatggattga ctcacgaaat aactaccaag
    14881 aaatcatgct tggctactct gacagtaata aagatggcgg ttacttgtca tcatgttgga
    14941 ccctctacaa ggctcaacaa caattgactg ctattggaga tgaatttggc gttaaggtta
    15001 ccttcttcca tggtcgtggt ggtactgtcg gtcgtggtgg tgggccaacc tatgaagcca
    15061 ttacgtctca accgctcaag tctatcaagg atcgtatccg cttgacggag cagggtgaag
    15121 taattgggaa taaatacggt aacaaagacg ccgcttacta taaccttgaa atgctagtat
    15181 cggcagctat taaccgtatg attactcaga agaagagcga taccaatacc ccaaatcgtt
    15241 atgaagccat tatggatcaa gtagtggacc gtagttacga tatctaccgt gatttggtct
    15301 ttggtaatga gcatttctat gattatttct tcgagtcaag tccaatcaag gctatttcaa
    15361 gttttaatat tggttctcgt ccagccgctc gtaagactat tactgaaatc ggtggattgc
    15421 gtgccatccc ttgggtattc tcatggtcac agagtcgtgt tatgttccct ggatggtacg
    15481 gggttggttc aagcttcaag gaatttatca ataaaaatcc agagaatatt gctatcttac
    15541 gagatatgta ccaaaattgg cctttcttcc aatcgcttct ttcaaatgtt gatatggttt
    15601 tgtcaaaatc aaatatgaat attgcttttg aatatgctaa actttgtgaa gacgagcaag
    15661 ttaaggccat ctatgagact attttaaatg aatggcaagt tactaagaac gttatcttgg
    15721 ctattgaagg acatgacgaa ctcttagctg acaatccata tctaaaagct agtctggatt
    15781 accgtatgcc ttactttaat attctcaact atattcagtt agagttgatt aaacgccaac
    15841 gtcgtggaga attgtccagt gatcaagaac gattgattca tatcaccatc aacggaattg
    15901 cgacaggatt gcgtaattca ggttgataat tttcaagagt gaatgctaaa agtgaatatc
    15961 aaaaaaattc taatagacta ttgacaagta gtttaaaaat gatataattt aaccattcag
    16021 aaaagtaatc atacaaactt tttagagagt ctgtggtagc tgaaaacaga taagtggcaa
    16081 tgatgaaaat tgggctgaat gctatttaga atttgaaatt ataaaaattc ggtaagcaca
    16141 ccttacagtg catctcgtta ttgcgagact gagcgatagg gaaattccct ataattgagg
    16201 tggtaccgcg catcgacgtc ctcacacaag ttttttgtgt gaggattttt ttgatggagg
    16261 ttagtatgga aagaaaacaa tggcgtcgct tgtttagata agtgaaatat gttaaaggaa
    16321 ataaaaagga gaaacagaat gaaaaataaa cgtttaattg gaattattgc tgcattagca
    16381 gtcttagtag caggaagctt gatttattct tcaatgaata aatcagaagc tcagaataat
    16441 aaggatgaga agaaaataac taagattggt gtgcttcaat ttgtgagcca tccatccctt
    16501 gatttgattt ataaagggat ccaagatgga cttgcagaag aaggatataa agatgatcaa
    16561 gttaaaattg attttatgaa ctcagaaggt gaccaaagta aggttgcgac aatgagtaaa
    16621 caattggttg caaatgggaa tgaccttgtg gttggtatcg caacaccagc agcccaaggg
    16681 ttggctagtg caacaaaaga cctaccagtt atcatggccg ctattacaga cccaattggt
    16741 gctaacttgg ttaaagattt gaaaaaacca ggtggcaacg ttacaggggt atctgaccac
    16801 aatccagctc aacaacaaat tgaactcatc aaggctctga caccgaatgt gaaaacaatc
    16861 ggagctcttt actcaagtag cgaagacaat tcaaaaacac aggtcgaaga atttaaggct
    16921 tatgctgaaa aagcaggtct gacagtggaa acatttgcag ttccttcaac aaatgaaatt
    16981 gcctcaactg tcactgttat gactagcaag gtagatgcta tttgggttcc aattgataac
    17041 accattgcat caggatttcc aacggttgtc tctagcaatc aaagttctaa gaaaccaatt
    17101 tatcccagtg cgacagctat ggtagaagta ggtggtttgg catcagttgt aattgaccaa
    17161 catgaccttg gtgtggcaac aggtaaaatg attgtgcaag tcttgaaagg tgcaaaacca
    17221 gccgataccc cagtcaatgt cttttcaact ggtaagtcag tcatcaataa aaaaatagca
    17281 caagaactag gtattactat tcctgagtct gttctcaaag aagcaggaca agtcatcgaa
    17341 taaataaggt agggaggagg agactcttcc cattttttaa aaagatgaat atagaaagga
    17401 ttaaataaaa tatgattgtt tccattattt ctcaaggatt tgtctgggct attctaggtc
    17461 tgggaatctt tatgacattt aggattttaa actttccaga tatgacgaca gaaggttcct
    17521 tccctcttgg gggagctgtt gctgtcactt tgataaccaa aggcgtgaac ccatttttag
    17581 cgacacttgt tgctgtagga gcaggttgtt tggctggaat ggcagcaggc cttctttata
    17641 caaaagggaa gatcccaacc ttgctctcag ggattttggt gatgacttct tgtcactcaa
    17701 tcatgctctt gattatggga cgtgcaaatt taggcctgct tggaaccaag caaattcagg
    17761 atgttttgcc ttttgattcg gatttgaatc aactcttgac aggtctcatc tttgtgagca
    17821 ttgttattgc tctcatgctc tttttcttgg acactaaact cggacaagcc tatattgcta
    17881 caggggataa tcctgatatg gctagaagtt tcgggattca tactggacgc atggagctca
    17941 tgggcttggt cttatcaaat ggtgtgattg cccttgcagg tgccctcatt gctcagcaag
    18001 aaggctatgc cgatgtgtct cgagggatcg gggttatcgt tgtgggactt gcaagtttga
    18061 ttattggaga agttattttc aagagtttga gcttggcaga gcgtttggtt actatcgttg
    18121 taggttctat cgcttatcaa tttttagtgt gggcagttat cgcacttggc tttaatacaa
    18181 gttaccttcg tttatacagt gccttgattt tagcagtctg cctcatgatt ccaatattta
    18241 agcaaacaat cttgaaagga gccaagttaa gcaaatgaca gcaattgtag aattaaaaaa
    18301 tgcaaccaaa atcgttaaaa atggctttga tgaagaaaag attattttaa atgatgtttc
    18361 cttagaaatt tttgaacggg actttatcac gattttgggc ggaaatggtg ctggaaaatc
    18421 aaccctcttt aacactatag cagggacctt atcactaact agtggaacta tccgtatttt
    18481 aggtgaagaa ctcactaagt tttcacccga gaagcgtgcc aagtacctgt ctcgtgtctt
    18541 ccaagatcca aagatgggga cagctccccg tatgacggtc gctgaaaatc ttttaatcgc
    18601 caagtttcgt ggtgaaaagc gtggattgtt accacgacgc ttgactagct ataaggatga
    18661 atttcaggca accattgaaa aagtaggaaa tggtcttgag aaacacttga atacaccgat
    18721 tgagttctta tcaggtggac aaagacaggc tttgagtctc ttgatggcaa ccttgaagcg
    18781 acctgaatta ctcttgttag acgagcatac tgctgccctg gatccaaaga ctagtgttgc
    18841 tttgatggga ttgacagatg aatttgttaa gaaagatcag ctaacagccc ttatgattac
    18901 tcatcatatg gaagatgctc tcaaatacgg caatcgcttg attgtcatga aagaaggacg
    18961 gattatccaa gatttaaacc aagaagaaaa agcaaaaatg aaaatctctg attattatca
    19021 actctttgaa taaagtaggg aaaatgagtg aaatggttta ctttttttct gaaataaagt
    19081 atactatata aagtaaacta tgataacatg gaggtattgt gtatggttga caaacaagtc
    19141 attgaagaaa tcaaaaacaa tgccaacatt gtggaagtca taggagatgt gatttcttta
    19201 caaaaggcag gacggaacta tctagggctc tgtccttttc atggtgaaaa aacaccttct
    19261 ttcaacgttg tagaggacaa gcagttttac cactgttttg gttgtggtcg ctcaggtgat
    19321 gtctttaaat tcatcgagga gtaccaaggg gttaccttta tggaggctgt ccaaatctta
    19381 ggtcagcgtg tcgggattga ggttgaaaaa ccgctttata gtgaacagaa gccagcctcg
    19441 cctcaccaag ctctttatga tatgcacgaa gatgcagcca aattttacca tgctattctc
    19501 atgacaacga ctatgggaga agaggccaga aattaccttt atcagcgggg tttgacagat
    19561 gaagtgctta aacatttttg gattggttta gcacctccag aacgaaacta tctctatcaa
    19621 cgtttgtctg atcagtatcg tgaagaggat ttactggatt caggcctgtt ttatctctcg
    19681 gatgccaatc aatttgtaga cacctttcac aatcgcatta tgtttcccct gacaaatgac
    19741 caaggaaagg tcattgcctt ctcaggtcgt atctggcaaa aaacggattc acaaacttct
    19801 aagtataaaa acagccgatc gactgcaatt tttaacaaaa gttacgaatt atatcatatg
    19861 gatagggcaa aaagatcttc tggaaaagct agtgagattt acctgatgga aggattcatg
    19921 gatgttattg cagcctatcg ggctggaatc gaaaatgctg tggcgtcgat gggaacggcc
    19981 ttgagtcgag agcatgttga gcatctgaaa aggttaacca agaaattggt tcttgtttac
    20041 gatggagata aggctgggca agccgcgata ttgaaagcat tggatgaaat tggtgatatg
    20101 cctgtgcaaa tcgttagcat gcctgataac ttggatcctg atgagtatct acaaaaaaat
    20161 ggtccagaag acttggccta tctattaaca aaaactcgta ttagtccgat tgagttctac
    20221 attcatcagt acaaacctga aaacagtgaa aatctgcagg ctcagattga gtttattgaa
    20281 aaaatagctc ccttgattgt tcaagaaaag tccatcgctg ctcaaaacag ctatattcat
    20341 attttagctg acagtctggc gtcctttgat tatacccaga ttgagcagat tgttaatgag
    20401 agtcgtcagg tgcaaaggca gaatcgcatg gaaggaattt ccagaccgac gccaatcacc
    20461 atgcctatca ccaagcagtt atcggctatt atgagggcag aagcccatct actctatcgg
    20521 atgatggaat cccctcttgt tttgaacgat taccgtttgc gagaagactt tgcatttgct
    20581 acacctgaat ttcaggtctt atatgacttg cttggccagt atggaaatct tcctccagaa
    20641 gttttagcag agcagacaga ggaagttgaa agagcttggt accaagtttt aactcaggat
    20701 ttgcctgctg agatatcgcc gcaggaactt agtgaagtag agatgactcg aaacaaggct
    20761 ctcttgaatc aggacaatat gagaatcaaa aagaaggtgc aggaagctag ccatgtagga
    20821 gatacagata cagccctaga agaattggaa cgtttaattt cccaaaagag aagaatggag
    20881 taataatggc aacaaaacaa aaagaagtaa caacatttga cgtacaggta gcagaattta
    20941 tccgtaatca taagcaaaaa gggacagcaa cagatgatga aatcaatgca agtttggtta
    21001 ttccttttac cttggacgct gatgggattg aagatctctt gcaacggatt caggatgcag
    21061 gaatttctat cacagataac gaaggaaatc caagtgcgcg tgttcttagc aatgaagaag
    21121 aaccagaact cagcgatgag gacttgattg ggtcaacttc tgctaaggtc aatgaccctg
    21181 tccgtatgta cttgaaagaa ataggggtcg ttcctctctt gaccaatgaa gaggagaaag
    21241 agttggcact ggctgttgaa gctggtgata tcgaagccaa acaacgtctt gcggaagcca
    21301 atcttcgttt ggttgtttcc attgccaaac gctatgtcgg tcgtggtatg cagttccttg
    21361 acttgattca agaaggaaat atgggcttga tgaaggcggt tgacaagttt gactattcta
    21421 aagggttcaa gttttcaact tatgcaactt ggtggattcg tcaggctatc actcgtgcta
    21481 ttgcggacca agctcgtacc atccgtatcc cagttcacat ggttgaaact atcaataaat
    21541 tggttcgtga acagcggaat ctccttcaag aattggggca agatccgaca ccagaacaga
    21601 ttgctgaacg aatggatatg acacctgata aggttcgtga aatcttgaag attgcccaag
    21661 aaccagtatc tctcgaaact cctatcggtg aagaggacga tagccacctt ggagacttta
    21721 tcgaagatga agtgattgaa aatccagtgg attatacgac tcgtatcgtc ttgcgtgagc
    21781 aattggatga aatcttagat actcttacag accgtgaaga aaatgttctg cgtctacgtt
    21841 ttggactaga tgatggaaaa atgcgcacac ttgaagatgt ggggaaagtc tttaacgtaa
    21901 ctcgtgagcg tatccgtcag attgaagcaa aggctttgag aaaactacgc caaccaagtc
    21961 gtagcaaacc gcttcgtgat tttattgaag actaagagtg aggaaaatat ggcttataca
    22021 gaagagcaaa ttgaaaacat caaaacacgg attttaacag ccttggaaga agtcatcgac
    22081 cctgagttgg gaatcgatat tgtcaatctt ggtttgatct atgagattcg ttttgacggt
    22141 gacacagggc aaacagagat tgacatgact ttgacaacta tgggttgtcc cttagcagac
    22201 cttttgacag accagattta tgatgctatg atagaggttc cagaagtaac ggatactgag
    22261 gttaaattag tctggtatcc agcctggaca gttgaaaaaa tgagtcgcta tgcccgcatt
    22321 gccctaggca ttaagtaaac atataaaagc atgtgagaga ctgttggaaa agcgaggaaa
    22381 tttcccctct tttcctctag tctctccttt cttttgctga ttttattcaa agaaaatgat
    22441 ataatagtag ttatggagaa aaagaaatta cgcatcaata tgttgagttc aagtgagaaa
    22501 gtagcaggac agggagtttc aggtgcttac cgtgaattag ttcgtcttct tcaccgtgct
    22561 gccaaggacc aattgattgt tacagaaaat cttccaatcg aggcagatgt gactcacttt
    22621 catacgattg attttcccta ttatttatca accttccaaa agaaacgctc agggagaaag
    22681 attggctatg tgcatttctt gccagctaca cttgagggaa gtttgaaaat tccatttttc
    22741 ttaaagggaa ttgtgaaacg ctatgtattt tctttttaca accggatgga gcacttggtt
    22801 gtggtcaatc ctatgtttat tgaggatttg gtagcagctg gtattccacg tgaaaaagtg
    22861 acctatattc ctaactttgt caacaaggaa aaatggcatc ctctaccaca agaagaggta
    22921 gtcagactgc gcacagatct tggtcttagt gacaatcagt ttatcgtagt aggtgctggg
    22981 caagttcaga aacgtaaagg gattgatgac tttatccgtc tggctgagga attgcctcag
    23041 attaccttta tctgggctgg tggcttctct tttggtggta tgacagatgg ttatgaacac
    23101 tataagaaaa ttatggaaaa tccccctaaa aatttgattt ttccaggcat tgtatcgcca
    23161 gagcggatgc gcgaattgta tgctctagcg gatcttttct tgttgcctag ttacaatgag
    23221 ctctttccta tgactatttt agaagctgcg agttgtgagg ctcctattat gttgcgtgat
    23281 ttagatctct ataaggtgat tttggaggga aattatcggg cgacagcggg tagagaagag
    23341 atgaaagagg ctattttgga atatcaagca aatcctgctg ccttaaaaga tctcaaagaa
    23401 aaggctaaga atatttccag agagtattct gaagagcatc tgttacaaat ctggttggat
    23461 ttttatgaga aacaagccgc tttagggaga aagtaaaaag tgaggtaatc tatgcgaatt
    23521 ggtttattta cagataccta ttttcctcag gtttctggtg ttgcgaccag tattcgaacc
    23581 ttgaaaacag aacttgaaaa gcagggacat gctgttttta tctttacgac gacagataag
    23641 gatgtcaatc gctacgaaga ttggcaaatt atccgcattc caagtgttcc tttctttgct
    23701 tttaaggatc gtcgctttgc ctaccgaggt tttagcaagg cacttgaaat tgctaaacag
    23761 tatcagctag atattatcca tactcagaca gaattttctc ttggcctgtt ggggatttgg
    23821 attgcgcgtg aattgaaaat tccagtcatc catacctatc acacccagta tgaagactat
    23881 gtccattata ttgctaaggg gatgttgatc cggccgagta tggtcaagta tctggttaga
    23941 ggtttcctgc atgatgtgga tggggttatt tgccctagtg agattgtccg tgacttgcta
    24001 tctgattata aggtcaaggt tgaaaaacgg gtcattccta ctgggattga attagccaag
    24061 tttgagcgtc cggaaatcaa gcaggaaaat ttgaaagaac tgcgtagtaa actagggatt
    24121 caagatggtg aaaagacgtt gcttagtctt tcgagaatct cctatgaaaa aaatattcaa
    24181 gcagttttag cagcctttgc tgatgttctg aaagaggaag acaaggttaa actggtagta
    24241 gctggggatg gcccttatct gaatgacctc aaagagcaag cccagaacct agagattcaa
    24301 gactcagtca tctttacagg gatgattgct cctagtgaga cggctcttta ctataaagcg
    24361 gcggatttct tcatttcagc atcgacaagc gaaacgcaag gtttgaccta cttggaaagc
    24421 ttagccagtg gaacacctgt cattgctcac ggaaatcctt atttgaacaa cctcatcagt
    24481 gataaaatgt ttggaacctt gtactatgga gaacatgatt tggctggtgc tattttggaa
    24541 gccctgattg caacaccaga catgaacgag cataccttat cagagaaatt gtatgagatt
    24601 tcagctgaga actttgggaa acgagtgcat gagttttatc tggatgccat tatttcaaat
    24661 aacttccaga aagatttggc taaagatgat acggtcagtc agcgtatctt taagacagtt
    24721 ttgtatcttc agcaacaggt ggttgctgta cctgtaaaag gatctagacg catgttgaag
    24781 gcttcaaaaa cacagttgat cagtatgaga gactattgga aagaccatga agaatagaaa
    24841 gaggaacagc tatgaaaaaa acaattaatg agaagcggtc gtgataaaaa gattgcgggt
    24901 gtttgtgctg gggtggccca ttatctggat atggatccga ctatcgttca agtcatttgg
    24961 ggtgttctta cttgctgtta cggagctgga attgtagctt acattatttt atggattatc
    25021 gcaccagtag caactgacta ttgaaaacta gctcaattca tgctaagata atagaaaata
    25081 gaatgtaacg aaggagagaa aaatggcatt tggagataat ggaaatcgta aaaaaactat
    25141 gtttgagaaa ataaccttgt ttatcgtgat tatcatgcta gtagcaagtt tattgggaat
    25201 ttttgcaact gcaattggtg ccctcagtaa tctataaaat agattcaaga aaatttagtg
    25261 actgggattt cccagccctt ttttaaagtg agaagaaata atgagtatgt ttttagatac
    25321 agctaagatt aaggtcaagg ctggtaatgg tggcgatggt atggttgcct ttcgtcgtga
    25381 aaaatatgtc cctaatggag gcccttgggg tggtgatggt ggtcgtggag gcaatgtggt
    25441 cttcgttgta gacgaaggac tacgtacctt gatggatttc cgctacaatc gtcatttcaa
    25501 ggctgattct ggtgaaaaag ggatgaccaa agggatgcat ggtcgtggtg ctgaggacct
    25561 tagagttcga gtaccacaag gtacgactgt tcgtgatgcg gagactggca aggttttaac
    25621 agatttgatt gaacatgggc aagaatttat cgttgcccac ggtggtcgtg gtggacgtgg
    25681 aaatattcgt ttcgcgacac caaaaaatcc tgcaccggaa atctctgaaa atggagaacc
    25741 aggtcaggaa cgtgagttac aattggaact aaaaatcttg gcagatgtcg gtttagtagg
    25801 attcccatct gtagggaagt caacactttt aagtgttatt acctcagcta agcctaaaat
    25861 tggtgcctac cactttacca ctattgtacc aaatttaggt atggttcgca cccaatcagg
    25921 tgaatccttt gcagtagccg acttgccagg tttgattgaa ggggctagtc aaggtgttgg
    25981 tttgggaact cagttcctcc gtcacatcga gcgtacacgt gttatccttc acatcattga
    26041 tatgtcagct agcgaaggcc gtgatccata tgaggattac ctagctatca ataaagagct
    26101 ggagtcttac aatcttcgcc tcatggagcg tccacagatt attgtagcta ataagatgga
    26161 catgcctgag agtcaggaaa atattgaaga ctttaagaaa aaattggctg aaaattatga
    26221 tgaatttgaa gagttaccag ctatcttccc aatttctgga ttgaccaagc aaggtctggc
    26281 aacactttta gatgctacag ctgaattgtt agacaagaca ccagaatttt tgctctacga
    26341 cgagtccgat atggaagaag aagcttacta tggatttgac gaagaagaaa aagcctttga
    26401 aattagtcgt gatgacgatg cgacatgggt actttctggt gaaaaactca tgaaactctt
    26461 taatatgacc aactttgatc gtgatgaatc tgtcatgaaa tttgcccgtc agcttcgtgg
    26521 tatgggggtt gatgaagccc ttcgtgcgcg tggagctaaa gatggggatt tggtccgcat
    26581 tggtaaattt gagtttgaat ttgtagacta ggagactggt atgggagata aaccgatatc
    26641 tttccgagat gcggatggta attttgtttc cgccgcagac gtttggaatg aaaagaaatt
    26701 ggaagaacta tttaatcgtc tcaatccaaa tcgtgccttg agattggcac gaactaaaaa
    26761 ggaaaatcca tctcagtaaa gaagctaaaa aatcccgtgc ctcatcagac acgggatttt
    26821 gtggtacgac gggcatgtat agcgaactga atctggaata gcacagcata tcttctaaaa
    26881 tatagtaaaa tgaaatgaga acaggacaaa tcgatcagga
//
